p.value	UP.DOWN	statistic	FDRp.value	path.name
hsa04211__43 59 60 61	4.21815624656157e-12	UP	6.93099629760537	2.64332757656219e-09	Longevity regulating pathway - mammal: ULK3 RB1CC1 ATG13 ATG101
hsa04750__8	4.21815624656157e-12	DOWN	-6.93099629760537	2.64332757656219e-09	Inflammatory mediator regulation of TRP channels: ASIC2
hsa04530__11 24 23	4.22032077152026e-12	DOWN	-6.93099629760537	2.64332757656219e-09	Tight junction: TJP1 YBX3 CDK4
hsa05120__20	3.60094073086607e-11	UP	6.62102829235388	1.01343931995038e-08	Epithelial cell signaling in Helicobacter pylori infection: CXCL8
hsa04530__11 36 14	3.8107661766693e-11	DOWN	-6.61265077869843	1.01343931995038e-08	Tight junction: TJP1 CTNNB1 CTNNA1
hsa05034__84	4.77638136587989e-11	DOWN	-6.57914072407665	1.01343931995038e-08	Alcoholism: FOSB
hsa04925__33	5.44622539183532e-11	DOWN	-6.55959319221395	1.01343931995038e-08	Aldosterone synthesis and secretion: CYP11B2
hsa05169__45	6.09284993320262e-11	DOWN	-6.54283816490305	1.01343931995038e-08	Epstein-Barr virus infection: RB1
hsa04722__53	6.32463649548527e-11	DOWN	-6.53725315579942	1.01343931995038e-08	Neurotrophin signaling pathway: JUN
hsa05012__71	6.81437368192247e-11	DOWN	-6.52608313759216	1.01343931995038e-08	Parkinson's disease: PRKACA*
hsa04071__65	6.94248975990043e-11	UP	6.52329063304035	1.01343931995038e-08	Sphingolipid signaling pathway: BAX*
hsa04110__59 15 16 17 18 19 20	7.76213904072337e-11	UP	6.50653560572946	1.01343931995038e-08	Cell cycle: CDC45 MCM7 MCM6 MCM5 MCM4 MCM3 MCM2
hsa03460__25 40	8.51684410042303e-11	UP	6.49257308297038	1.01343931995038e-08	Fanconi anemia pathway: MLH1 PMS2
hsa04115__11 12	8.67617305059026e-11	UP	6.48978057841857	1.01343931995038e-08	p53 signaling pathway: CDK2 CCNE1
hsa04914__39	8.67617305059026e-11	DOWN	-6.48978057841857	1.01343931995038e-08	Progesterone-mediated oocyte maturation: PIK3R5
hsa03460__7	8.83841516696346e-11	UP	6.48698807386675	1.01343931995038e-08	Fanconi anemia pathway: FANCI
hsa04970__18	9.34314480429015e-11	DOWN	-6.4786105602113	1.01343931995038e-08	Salivary secretion: VAMP2
hsa05030__77	9.87601909725459e-11	DOWN	-6.47023304655586	1.01343931995038e-08	Cocaine addiction: BDNF
hsa05020__49	1.02476567743785e-10	UP	6.46464803745223	1.01343931995038e-08	Prion diseases: BAX
hsa04914__34	1.18757914193418e-10	DOWN	-6.44230800103771	1.06973251485033e-08	Progesterone-mediated oocyte maturation: MAPK14
hsa05034__99	1.20962956290035e-10	DOWN	-6.43951549648589	1.06973251485033e-08	Alcoholism: PDYN
hsa04211__29	1.30190282166661e-10	DOWN	-6.42834547827863	1.06973251485033e-08	Longevity regulating pathway - mammal: EIF4E
hsa04919__40	1.32602534640487e-10	DOWN	-6.42555297372682	1.06973251485033e-08	Thyroid hormone signaling pathway: RCAN2
hsa04066__88	1.42695970347859e-10	DOWN	-6.41438295551955	1.06973251485033e-08	HIF-1 signaling pathway: BCL2
hsa04151__2	1.48020465067102e-10	DOWN	-6.40879794641592	1.06973251485033e-08	PI3K-Akt signaling pathway: EIF4E
hsa04210__74	1.48020465067102e-10	UP	6.40879794641592	1.06973251485033e-08	Apoptosis: BAX*
hsa04211__38	1.56373080088571e-10	UP	6.40042043276048	1.08824080550528e-08	Longevity regulating pathway - mammal: BAX
hsa04931__149	1.74482937401554e-10	DOWN	-6.38366540544959	1.15133571408271e-08	Insulin resistance: ACACB*
hsa04068__58	1.77694176202228e-10	DOWN	-6.38087290089777	1.15133571408271e-08	FoxO signaling pathway: KLF2
hsa04152__64	2.21033197817767e-10	DOWN	-6.34736284627599	1.38440459566528e-08	AMPK signaling pathway: ACACB
hsa03460__27	2.29196777634308e-10	UP	6.34177783717236	1.3892282102415e-08	Fanconi anemia pathway: BRCA1
hsa04924__31	2.69722274822249e-10	DOWN	-6.31664529620602	1.58377548247189e-08	Renin secretion: C02135
hsa04710__7	2.89912554691329e-10	DOWN	-6.30547527799876	1.65074451595456e-08	Circadian rhythm: PER1
hsa04960__4	3.17227803509221e-10	DOWN	-6.29151275523969	1.75315012586419e-08	Aldosterone-regulated sodium reabsorption: ATP1B4
hsa04022__65	3.34806618084428e-10	DOWN	-6.28313524158424	1.77917753622395e-08	cGMP-PKG signaling pathway: PDE2A
hsa05012__70	3.40874887195648e-10	DOWN	-6.28034273703242	1.77917753622395e-08	Parkinson's disease: PRKACA
hsa04914__30	3.59726739663366e-10	UP	6.27196522337698	1.79197620765717e-08	Progesterone-mediated oocyte maturation: CDK1*
hsa04152__44	3.66240007485521e-10	DOWN	-6.26917271882516	1.79197620765717e-08	AMPK signaling pathway: SLC2A4
hsa04010__54	3.7286378153231e-10	DOWN	-6.26638021427335	1.79197620765717e-08	MAPK signaling pathway: NR4A1
hsa04910__17	3.93444590784331e-10	DOWN	-6.2580027006179	1.79197620765717e-08	Insulin signaling pathway: C00031
hsa04664__3 4 5	4.00544904177919e-10	DOWN	-6.25521019606609	1.79197620765717e-08	Fc epsilon RI signaling pathway: FCER1G MS4A2 FCER1A
hsa04728__74	4.00548167757324e-10	DOWN	-6.25521019606609	1.79197620765717e-08	Dopaminergic synapse: GRIN2A
hsa04540__14 31	4.15132903942082e-10	DOWN	-6.24962518696246	1.8140342476911e-08	Gap junction: GJA1 TJP1
hsa04261__66	4.62066964539266e-10	DOWN	-6.23287015965157	1.97323596902109e-08	Adrenergic signaling in cardiomyocytes: C01245
hsa05215__13	5.0510152411437e-10	DOWN	-6.21890763689249	2.08558912140264e-08	Prostate cancer: BCL2
hsa04110__10 11 12 13 14 9 15 16 17 18 19 20	5.23389505051563e-10	UP	6.21332262778886	2.08558912140264e-08	Cell cycle: ORC3 ORC5 ORC4 ORC2 ORC1 ORC6 MCM7 MCM6 MCM5 MCM4 MCM3 MCM2
hsa05221__35	5.23389505051563e-10	UP	6.21332262778886	2.08558912140264e-08	Acute myeloid leukemia: EIF4EBP1
hsa04530__11 13	5.32774230054959e-10	DOWN	-6.21053012323704	2.08558912140264e-08	Tight junction: TJP1 EPB41
hsa04919__39	5.61924476930322e-10	DOWN	-6.2021526095816	2.14951106812895e-08	Thyroid hormone signaling pathway: ESR1
hsa04933__19	5.7198272169477e-10	DOWN	-6.19936010502978	2.14951106812895e-08	AGE-RAGE signaling pathway in diabetic complications: TGFBR2
hsa04713__60	6.47477909313586e-10	DOWN	-6.17981257316708	2.33643847146769e-08	Circadian entrainment: PER1
hsa04152__62	6.59027349589077e-10	UP	6.17702006861526	2.33643847146769e-08	AMPK signaling pathway: EIF4EBP1
hsa04550__36	6.59027349589077e-10	DOWN	-6.17702006861526	2.33643847146769e-08	Signaling pathways regulating pluripotency of stem cells: AKT3*
hsa04728__70 73	6.82732339424032e-10	DOWN	-6.17143505951163	2.37565567736621e-08	Dopaminergic synapse: KIF5A GRIA1
hsa05030__73	8.43441045107685e-10	DOWN	-6.13792500488985	2.88019791996587e-08	Cocaine addiction: NFKB1
hsa04151__103	8.58387884609305e-10	DOWN	-6.13513250033803	2.88019791996587e-08	PI3K-Akt signaling pathway: BCL2*
hsa05030__37	9.04795166003745e-10	DOWN	-6.12675498668259	2.93251778165899e-08	Cocaine addiction: PRKACA
hsa04213__60	9.20801219360727e-10	DOWN	-6.12396248213077	2.93251778165899e-08	Longevity regulating pathway - multiple species: CAT
hsa04914__11	9.20801219360727e-10	UP	6.12396248213077	2.93251778165899e-08	Progesterone-mediated oocyte maturation: CDK1
hsa03460__48	9.37083285552146e-10	UP	6.12116997757896	2.93463248925414e-08	Fanconi anemia pathway: RAD51
hsa04114__80	9.70494053773353e-10	UP	6.11558496847533	2.98943988039366e-08	Oocyte meiosis: CDC25C*
hsa04540__14 16	1.00506542646476e-09	DOWN	-6.1099999593717	2.99764751797981e-08	Gap junction: GJA1 GJA1
hsa04540__14 15	1.00506542646476e-09	DOWN	-6.1099999593717	2.99764751797981e-08	Gap junction: GJA1 GJA1*
hsa04610__11	1.0227985399842e-09	UP	6.10720745481988	3.00287258848487e-08	Complement and coagulation cascades: F2R
hsa04931__61	1.07784807207284e-09	DOWN	-6.09882994116444	3.1158100421921e-08	Insulin resistance: ACACB
hsa04115__38	1.1557604846061e-09	UP	6.08765992295717	3.29041507662859e-08	p53 signaling pathway: GTSE1
hsa04012__22	1.1760807629756e-09	UP	6.08486741840536	3.29829216959872e-08	ErbB signaling pathway: EIF4EBP1
hsa04066__42	1.2830218705088e-09	DOWN	-6.07090489564628	3.49391028215368e-08	HIF-1 signaling pathway: HK1
hsa04550__34	1.2830218705088e-09	DOWN	-6.07090489564628	3.49391028215368e-08	Signaling pathways regulating pluripotency of stem cells: MAPK1*
hsa04360__108	1.37534629826098e-09	DOWN	-6.05973487743902	3.69182242061769e-08	Axon guidance: CFL1
hsa04530__1 5	1.44880802873924e-09	DOWN	-6.05135736378358	3.83423983943808e-08	Tight junction: IGSF5 IGSF5
hsa04728__68	1.49989260888185e-09	DOWN	-6.04577235467995	3.8606824823137e-08	Dopaminergic synapse: CACNA1C
hsa04925__18	1.49989260888185e-09	DOWN	-6.04577235467995	3.8606824823137e-08	Aldosterone synthesis and secretion: PDE2A
hsa04071__59 60	1.52608901347551e-09	DOWN	-6.04297985012813	3.87502872475741e-08	Sphingolipid signaling pathway: TP53 BCL2
hsa04919__49	1.55272522263078e-09	DOWN	-6.04018734557632	3.89009425776432e-08	Thyroid hormone signaling pathway: ACTB
hsa05205__415	1.57982633216608e-09	DOWN	-6.0373948410245	3.90591273439483e-08	Proteoglycans in cancer: MAPK1******
hsa04152__54	1.72236501664858e-09	DOWN	-6.02343231826542	4.09661248896542e-08	AMPK signaling pathway: SLC2A4*
hsa04152__78	1.72236501664858e-09	UP	6.02343231826542	4.09661248896542e-08	AMPK signaling pathway: CCNA2
hsa05030__76	1.72236501664858e-09	DOWN	-6.02343231826542	4.09661248896542e-08	Cocaine addiction: PDYN
hsa05031__97	1.84534837429495e-09	DOWN	-6.01226230005816	4.28075258679038e-08	Amphetamine addiction: ARC
hsa05166__60	1.84534837429495e-09	UP	6.01226230005816	4.28075258679038e-08	HTLV-I infection: POLD3
hsa04630__31	1.97687243784868e-09	UP	6.0010922818509	4.52993086672887e-08	Jak-STAT signaling pathway: BCL2L1
hsa05205__284	2.01115458140697e-09	DOWN	-5.99829977729909	4.55296320296831e-08	Proteoglycans in cancer: PRKCA*
hsa04933__12	2.04601566041259e-09	DOWN	-5.99550727274727	4.57674217370863e-08	AGE-RAGE signaling pathway in diabetic complications: EGR1
hsa04919__28	2.47052543197514e-09	DOWN	-5.96478972267731	5.46131445491916e-08	Thyroid hormone signaling pathway: RCAN1
hsa04066__89	2.55642883855165e-09	DOWN	-5.95920471357367	5.52129860648109e-08	HIF-1 signaling pathway: CDKN1A
hsa04724__3	2.55642883855165e-09	DOWN	-5.95920471357367	5.52129860648109e-08	Glutamatergic synapse: GRIK1
hsa04010__13	2.73705052143054e-09	UP	5.94803469536641	5.84422492019088e-08	MAPK signaling pathway: STMN1
hsa03460__16 49	3.13633489617167e-09	UP	5.92569465895189	6.62154299989503e-08	Fanconi anemia pathway: FANCM C19orf40
hsa03460__28	3.19006854830959e-09	UP	5.92290215440008	6.66015422474858e-08	Fanconi anemia pathway: RAD51C
hsa04722__84	3.35670325340906e-09	DOWN	-5.91452464074463	6.93103891555562e-08	Neurotrophin signaling pathway: NFKB1*
hsa04014__26	3.65343827151617e-09	DOWN	-5.90056211798555	7.42760082879893e-08	Ras signaling pathway: PRKCA
hsa04340__50	3.7157768914694e-09	DOWN	-5.89776961343374	7.42760082879893e-08	Hedgehog signaling pathway: BCL2
hsa04960__3	3.7157768914694e-09	DOWN	-5.89776961343374	7.42760082879893e-08	Aldosterone-regulated sodium reabsorption: SCNN1A
hsa04664__23	3.97564889609863e-09	DOWN	-5.88659959522648	7.86341502712561e-08	Fc epsilon RI signaling pathway: AKT3
hsa04622__45	4.3254540849081e-09	UP	5.8726370724674	8.43426495946298e-08	RIG-I-like receptor signaling pathway: MAPK14
hsa04115__43 57	4.39892477928351e-09	UP	5.86984456791559	8.43426495946298e-08	p53 signaling pathway: CDK1 CCNB3
hsa04211__56	4.39892477928351e-09	DOWN	-5.86984456791559	8.43426495946298e-08	Longevity regulating pathway - mammal: CAT
hsa04724__66	4.54952743001186e-09	DOWN	-5.86425955881196	8.63491115251746e-08	Glutamatergic synapse: PLA2G4B
hsa04961__12	5.2916574941266e-09	DOWN	-5.83912701784562	9.94302443146387e-08	Endocrine and other factor-regulated calcium reabsorption: SLC8A1
hsa04213__71	5.56426036712851e-09	DOWN	-5.83074950419017	1.03517279503312e-07	Longevity regulating pathway - multiple species: SIRT1**
hsa04540__1	5.65806749084212e-09	DOWN	-5.82795699963836	1.04230478581297e-07	Gap junction: C00681
hsa05030__69	5.75353485873244e-09	DOWN	-5.82516449508654	1.04960116500566e-07	Cocaine addiction: PRKACA**
hsa04750__40	5.94906685153317e-09	DOWN	-5.81957948598291	1.07483621288758e-07	Inflammatory mediator regulation of TRP channels: C00219
hsa04066__45	6.15105692075808e-09	DOWN	-5.81399447687928	1.09834365470116e-07	HIF-1 signaling pathway: ALDOA
hsa04066__44	6.25453810819713e-09	DOWN	-5.81120197232747	1.09834365470116e-07	HIF-1 signaling pathway: GAPDH
hsa05231__39	6.25453810819713e-09	UP	5.81120197232747	1.09834365470116e-07	Choline metabolism in cancer: EIF4EBP1
hsa03320__22	6.68565903816743e-09	DOWN	-5.80003195412021	1.15250948006574e-07	PPAR signaling pathway: ACADM
hsa04925__3	6.68565903816743e-09	DOWN	-5.80003195412021	1.15250948006574e-07	Aldosterone synthesis and secretion: ITPR1
hsa04211__42	7.1456279129563e-09	DOWN	-5.78886193591295	1.22060316804044e-07	Longevity regulating pathway - mammal: PPARGC1A
hsa04530__11 62	7.63631383279232e-09	DOWN	-5.77769191770569	1.28112800819793e-07	Tight junction: TJP1 SHROOM1
hsa04919__32	7.63631383279232e-09	DOWN	-5.77769191770569	1.28112800819793e-07	Thyroid hormone signaling pathway: PLN
hsa04151__26	8.295904318991e-09	DOWN	-5.76372939494661	1.3554786274247e-07	PI3K-Akt signaling pathway: RBL2
hsa04713__61	8.295904318991e-09	DOWN	-5.76372939494661	1.3554786274247e-07	Circadian entrainment: FOS
hsa05200__189	8.295904318991e-09	UP	5.76372939494661	1.3554786274247e-07	Pathways in cancer: BIRC5
hsa05166__64	8.57497028161789e-09	UP	5.75814438584298	1.3889973413069e-07	HTLV-I infection: CCNB2
hsa04910__48	8.71790473615004e-09	DOWN	-5.75535188129116	1.40008059822444e-07	Insulin signaling pathway: PPARGC1A
hsa05034__62	8.86315440300176e-09	DOWN	-5.75255937673935	1.41134467146104e-07	Alcoholism: NPY
hsa04930__3	9.31316094469272e-09	DOWN	-5.7441818630839	1.47054028698131e-07	Type II diabetes mellitus: SLC2A4
hsa03460__16 34	1.01129792748346e-08	UP	5.73021934032483	1.58352400478452e-07	Fanconi anemia pathway: FANCM STRA13
hsa04922__17	1.02807695135582e-08	DOWN	-5.72742683577301	1.59649305090709e-07	Glucagon signaling pathway: PKM
hsa04923__66	1.08005369756684e-08	DOWN	-5.71904932211757	1.66345975223614e-07	Regulation of lipolysis in adipocytes: LIPE
hsa04666__38	1.09794013182961e-08	DOWN	-5.71625681756575	1.67725976236409e-07	Fc gamma R-mediated phagocytosis: CFL1
hsa04919__101	1.2114605263369e-08	DOWN	-5.69950179025486	1.83575349111858e-07	Thyroid hormone signaling pathway: NOTCH1
hsa05210__21	1.23145768406574e-08	UP	5.69670928570304	1.85112719068762e-07	Colorectal cancer: BIRC5
hsa04024__9 95	1.29339263055523e-08	DOWN	-5.6883317720476	1.89865996313538e-07	cAMP signaling pathway: ATP1B4 FXYD1
hsa05031__10	1.29339263055523e-08	DOWN	-5.6883317720476	1.89865996313538e-07	Amphetamine addiction: CACNA1C
hsa05031__53	1.29339263055523e-08	DOWN	-5.6883317720476	1.89865996313538e-07	Amphetamine addiction: CACNA1C*
hsa04270__10 3 71	1.35834970674027e-08	DOWN	-5.67995425839215	1.96333776843459e-07	Vascular smooth muscle contraction: ACTA2 MYL9 MYH11
hsa04919__21 53	1.35834970674027e-08	DOWN	-5.67995425839215	1.96333776843459e-07	Thyroid hormone signaling pathway: THRA C02465
hsa05200__194	1.38069812687174e-08	DOWN	-5.67716175384034	1.98040593923053e-07	Pathways in cancer: BCL2
hsa04520__43	1.4034035822723e-08	DOWN	-5.67436924928852	1.98270325645839e-07	Adherens junction: ACTB
hsa04913__35	1.4034035822723e-08	DOWN	-5.67436924928852	1.98270325645839e-07	Ovarian steroidogenesis: HSD17B2
hsa04622__21 22 23	1.42647159700118e-08	UP	5.67157674473671	2.00025382892927e-07	RIG-I-like receptor signaling pathway: CHUK IKBKB IKBKG
hsa05205__270	1.54744924503147e-08	DOWN	-5.65761422197763	2.15382009734381e-07	Proteoglycans in cancer: MAPK1****
hsa05164__20	1.5728133252969e-08	DOWN	-5.65482171742582	2.17302664575947e-07	Influenza A: ATF2
hsa05200__168	1.70581356822388e-08	UP	5.64085919466674	2.33957933919172e-07	Pathways in cancer: E2F1
hsa04261__4	1.7907899134983e-08	DOWN	-5.63248168101129	2.43832916482848e-07	Adrenergic signaling in cardiomyocytes: SLC8A1
hsa04114__59	1.84970956662763e-08	UP	5.62689667190766	2.50043473071462e-07	Oocyte meiosis: REC8*
hsa04740__37	1.87987100951544e-08	UP	5.62410416735585	2.5051614375032e-07	Olfactory transduction: CNGB1*
hsa05205__215 216	1.87987100951544e-08	DOWN	-5.62410416735585	2.5051614375032e-07	Proteoglycans in cancer: EIF4B RPS6
hsa04611__34	1.91050976756273e-08	DOWN	-5.62131166280403	2.52806186848618e-07	Platelet activation: C02198*
hsa05221__21	1.94163315174182e-08	DOWN	-5.61851915825222	2.55127880568034e-07	Acute myeloid leukemia: PIM1
hsa04722__50	2.03798580035382e-08	UP	5.61014164459677	2.65928841587835e-07	Neurotrophin signaling pathway: RHOA
hsa04010__67	2.07112298236116e-08	UP	5.60734914004496	2.68388971300457e-07	MAPK signaling pathway: ELK1
hsa04530__11 43	2.10478299668124e-08	DOWN	-5.60455663549314	2.70882688408497e-07	Tight junction: TJP1 ACTN4
hsa05020__48	2.13897382584157e-08	DOWN	-5.60176413094133	2.73410327806552e-07	Prion diseases: SOD1
hsa04213__61	2.20898044815373e-08	DOWN	-5.5961791218377	2.80450963654112e-07	Longevity regulating pathway - multiple species: ATG5
hsa04919__31	2.24481280073009e-08	DOWN	-5.59338661728588	2.83087466615559e-07	Thyroid hormone signaling pathway: ATP2A2
hsa04110__60 10 11 12 13 14 9	2.35572795531756e-08	DOWN	-5.58500910363044	2.95094188536113e-07	Cell cycle: CDC6 ORC3 ORC5 ORC4 ORC2 ORC1 ORC6
hsa04970__32	2.51191930879002e-08	DOWN	-5.57383908542317	3.12575919285857e-07	Salivary secretion: RYR3
hsa05110__51	2.55250248573693e-08	UP	5.57104658087136	3.15536327019717e-07	Vibrio cholerae infection: PDIA4
hsa04310__13	2.59373852064387e-08	DOWN	-5.56825407631954	3.16469784434405e-07	Wnt signaling pathway: NFATC1
hsa04916__6	2.59373852064387e-08	DOWN	-5.56825407631954	3.16469784434405e-07	Melanogenesis: DCT
hsa04730__7	2.85501672010631e-08	DOWN	-5.55149904900865	3.46101704327726e-07	Long-term depression: GNA13
hsa04152__24	2.99505927072356e-08	DOWN	-5.54312153535321	3.60751049339075e-07	AMPK signaling pathway: SIRT1
hsa04725__64	3.04320416222305e-08	DOWN	-5.54032903080139	3.64215326166696e-07	Cholinergic synapse: KCNJ3
hsa04960__27	3.24340235412831e-08	DOWN	-5.52915901259413	3.85718545785259e-07	Aldosterone-regulated sodium reabsorption: KCNJ1
hsa04310__14	3.51167168734808e-08	DOWN	-5.51519648983505	4.13826605812659e-07	Wnt signaling pathway: PRKCA
hsa04611__43	3.56785045990691e-08	DOWN	-5.51240398528324	4.13826605812659e-07	Platelet activation: MYL12B
hsa04664__47	3.56785045990691e-08	DOWN	-5.51240398528324	4.13826605812659e-07	Fc epsilon RI signaling pathway: MAPK8
hsa04725__61	3.56785045990691e-08	DOWN	-5.51240398528324	4.13826605812659e-07	Cholinergic synapse: FOS
hsa04530__30	3.92368310705533e-08	UP	5.49564895797235	4.48511852420926e-07	Tight junction: AKT3
hsa04915__3 11	3.98624158351755e-08	DOWN	-5.49285645342053	4.48511852420926e-07	Estrogen signaling pathway: ESR1 C00951
hsa04915__12 14	3.98624158351755e-08	DOWN	-5.49285645342053	4.48511852420926e-07	Estrogen signaling pathway: ESR1 FOS
hsa04915__12 13	3.98624158351755e-08	DOWN	-5.49285645342053	4.48511852420926e-07	Estrogen signaling pathway: ESR1 C00951*
hsa05020__52	3.98624158351755e-08	DOWN	-5.49285645342053	4.48511852420926e-07	Prion diseases: FYN
hsa04014__38	4.17977529844252e-08	DOWN	-5.48447893976509	4.67487963438899e-07	Ras signaling pathway: MAPK8
hsa04010__58	4.31382664948398e-08	UP	5.47889393066146	4.76804722022377e-07	MAPK signaling pathway: CDC25B
hsa04728__44	4.31382664948398e-08	DOWN	-5.47889393066146	4.76804722022377e-07	Dopaminergic synapse: FOS
hsa04261__39	4.52275052706697e-08	DOWN	-5.47051641700601	4.96973581307534e-07	Adrenergic signaling in cardiomyocytes: SCN1B
hsa04919__100	4.66744782284802e-08	DOWN	-5.46493140790238	5.09891538321595e-07	Thyroid hormone signaling pathway: CTNNB1*
hsa04010__78	5.12897994728252e-08	DOWN	-5.44817638059149	5.57072446297333e-07	MAPK signaling pathway: MAP3K4
hsa04211__50	5.46092491129383e-08	DOWN	-5.43700636238423	5.8971712116788e-07	Longevity regulating pathway - mammal: PPARGC1A*
hsa04530__14 20 43	5.54711002062098e-08	DOWN	-5.43421385783241	5.95601127356961e-07	Tight junction: CTNNA1 ACTB ACTN4
hsa04520__1 13	5.6346126265667e-08	DOWN	-5.4314213532806	6.01558927574933e-07	Adherens junction: SMAD4 SMAD2
hsa04213__55	5.72345217668986e-08	DOWN	-5.42862884872878	6.07591335593235e-07	Longevity regulating pathway - multiple species: CRYAB
hsa04550__66	5.90522128409247e-08	DOWN	-5.42304383962515	6.23365774876953e-07	Signaling pathways regulating pluripotency of stem cells: MYC
hsa04066__46	6.09257851373332e-08	DOWN	-5.41745883052152	6.35997501516939e-07	HIF-1 signaling pathway: ENO1
hsa04913__19	6.09257851373332e-08	DOWN	-5.41745883052152	6.35997501516939e-07	Ovarian steroidogenesis: STAR
hsa05160__55	6.28568963742383e-08	UP	5.41187382141789	6.5253098501212e-07	Hepatitis C: MAPK14
hsa05205__233 234	6.90127576545289e-08	DOWN	-5.395118794107	7.12499844136592e-07	Proteoglycans in cancer: ITGA2 C00925
hsa04919__104	7.11915666734181e-08	DOWN	-5.38953378500337	7.30977889504659e-07	Thyroid hormone signaling pathway: MYC
hsa04211__51	7.23058109310882e-08	UP	5.38674128045156	7.38383797497363e-07	Longevity regulating pathway - mammal: NFKB1
hsa05131__38	7.69341069671308e-08	UP	5.37557126224429	7.77199930060424e-07	Shigellosis: CXCL8
hsa05133__73	7.69341069671308e-08	DOWN	-5.37557126224429	7.77199930060424e-07	Pertussis: FOS
hsa04115__29	7.81352712860842e-08	DOWN	-5.37277875769248	7.80937099715703e-07	p53 signaling pathway: IGF1
hsa04920__40	7.81352712860842e-08	DOWN	-5.37277875769248	7.80937099715703e-07	Adipocytokine signaling pathway: PPARGC1A
hsa04668__40	8.44187343060533e-08	DOWN	-5.3588162349334	8.39274083391927e-07	TNF signaling pathway: JUN
hsa04630__24	8.57328605389838e-08	UP	5.35602373038159	8.4341384792016e-07	Jak-STAT signaling pathway: MCL1
hsa04916__9	8.57328605389838e-08	DOWN	-5.35602373038159	8.4341384792016e-07	Melanogenesis: PRKACA
hsa04022__37 38	9.69832605859203e-08	DOWN	-5.33368369396707	9.44204904875358e-07	cGMP-PKG signaling pathway: ATP2A1 PLN
hsa04066__56	9.69832605859203e-08	DOWN	-5.33368369396707	9.44204904875358e-07	HIF-1 signaling pathway: TEK
hsa04621__28	9.84862657691749e-08	UP	5.33089118941525	9.53895326702472e-07	NOD-like receptor signaling pathway: CASP8
hsa04664__46	1.00011806902389e-07	DOWN	-5.32809868486344	9.63703513690202e-07	Fc epsilon RI signaling pathway: PLA2G4B
hsa04922__59	1.03131804853437e-07	DOWN	-5.3225136757598	9.78710410705091e-07	Glucagon signaling pathway: CPT1C
hsa04970__27	1.03131804853437e-07	DOWN	-5.3225136757598	9.78710410705091e-07	Salivary secretion: PRKCA
hsa05030__78	1.03131804853437e-07	DOWN	-5.3225136757598	9.78710410705091e-07	Cocaine addiction: GRIA2
hsa05166__34 35 36	1.07988795136766e-07	DOWN	-5.31413616210436	1.01965299528635e-06	HTLV-I infection: MYC TRRAP KAT5
hsa04971__52 53	1.09656875041096e-07	DOWN	-5.31134365755254	1.0302263410111e-06	Gastric acid secretion: EZR ACTB
hsa04621__44	1.13067494739017e-07	UP	5.30575864844891	1.05698419211251e-06	NOD-like receptor signaling pathway: MAPK14
hsa05166__65	1.14811077297066e-07	UP	5.3029661438971	1.06797036753063e-06	HTLV-I infection: PTTG2
hsa04152__56	1.16580665005478e-07	UP	5.30017363934528	1.07908901253839e-06	AMPK signaling pathway: FASN
hsa04213__52	1.39985505112682e-07	DOWN	-5.2666635847235	1.28308665417917e-06	Longevity regulating pathway - multiple species: SOD2
hsa04921__58	1.39985505112682e-07	DOWN	-5.2666635847235	1.28308665417917e-06	Oxytocin signaling pathway: MEF2C
hsa04261__8 38	1.51025518573619e-07	DOWN	-5.25270106196442	1.37755800679529e-06	Adrenergic signaling in cardiomyocytes: ATP2A2 PLN
hsa04066__47	1.53332400476384e-07	DOWN	-5.24990855741261	1.39184338403443e-06	HIF-1 signaling pathway: PGK1
hsa05211__48	1.70461837979222e-07	DOWN	-5.2303610255499	1.53989323828345e-06	Renal cell carcinoma: JUN
hsa04020__16	1.75686557805832e-07	UP	5.22477601644627	1.57949780917301e-06	Calcium signaling pathway: C06124
hsa04390__12	1.81065941014743e-07	DOWN	-5.21919100734264	1.62010906269858e-06	Hippo signaling pathway: CTGF
hsa04962__10	1.86604393228232e-07	DOWN	-5.21360599823901	1.66175191884289e-06	Vasopressin-regulated water reabsorption: AQP2
hsa04066__43	1.89434679752281e-07	DOWN	-5.2108134936872	1.67899888327611e-06	HIF-1 signaling pathway: PFKL
hsa04923__16	1.92306440273355e-07	DOWN	-5.20802098913538	1.69644977123772e-06	Regulation of lipolysis in adipocytes: PLIN1
hsa04390__89	2.04220042003915e-07	DOWN	-5.19685097092812	1.79312831273531e-06	Hippo signaling pathway: ID2
hsa04340__52	2.07308107531657e-07	DOWN	-5.1940584663763	1.803388583574e-06	Hedgehog signaling pathway: BCL2*
hsa04724__67	2.07308107531657e-07	DOWN	-5.1940584663763	1.803388583574e-06	Glutamatergic synapse: PLD1
hsa05166__136 139	2.10441277857249e-07	UP	5.19126596182449	1.8222081156395e-06	HTLV-I infection: TP53 TBPL2
hsa04068__59	2.20117800602559e-07	DOWN	-5.18288844816904	1.88859062708771e-06	FoxO signaling pathway: S1PR1
hsa04921__41	2.20117800602559e-07	DOWN	-5.18288844816904	1.88859062708771e-06	Oxytocin signaling pathway: PTGS2
hsa04270__65	2.23434663241177e-07	DOWN	-5.18009594361723	1.89972695333531e-06	Vascular smooth muscle contraction: NPR2
hsa04151__109	2.23437816225175e-07	UP	5.18009594361723	1.89972695333531e-06	PI3K-Akt signaling pathway: RXRA
hsa04970__45	2.26802996035453e-07	DOWN	-5.17730343906541	1.91107101812685e-06	Salivary secretion: KCNMA1
hsa04068__55	2.26806193210371e-07	DOWN	-5.17730343906541	1.91107101812685e-06	FoxO signaling pathway: ATM
hsa04210__84	2.33690751612495e-07	DOWN	-5.17171842996178	1.9602898316066e-06	Apoptosis: FAS**
hsa04390__58	2.37208316061812e-07	DOWN	-5.16892592540997	1.98095300391175e-06	Hippo signaling pathway: SMAD7
hsa04020__42	2.48070644569021e-07	DOWN	-5.16054841175452	2.05341295658674e-06	Calcium signaling pathway: MYLK4
hsa04722__38	2.48070644569021e-07	DOWN	-5.16054841175452	2.05341295658674e-06	Neurotrophin signaling pathway: ATF4
hsa05164__78	2.55577495630025e-07	UP	5.15496340265089	2.10627243109131e-06	Influenza A: GSK3B
hsa04068__52	2.63303553256698e-07	DOWN	-5.14937839354726	2.15107555030146e-06	FoxO signaling pathway: CAT
hsa04520__44 52 45	2.63303553256698e-07	DOWN	-5.14937839354726	2.15107555030146e-06	Adherens junction: ACTB ACTN4 CTNNA1
hsa03320__20	2.71254970444563e-07	DOWN	-5.14379338444363	2.1969314201092e-06	PPAR signaling pathway: SCP2
hsa04210__75	2.71254970444563e-07	UP	5.14379338444363	2.1969314201092e-06	Apoptosis: BAK1*
hsa04390__60	2.79438065400669e-07	DOWN	-5.13820837534	2.24386378157204e-06	Hippo signaling pathway: CTGF*
hsa04916__4	2.79438065400669e-07	DOWN	-5.13820837534	2.24386378157204e-06	Melanogenesis: TYR
hsa04915__66	2.83618512692132e-07	DOWN	-5.13541587078819	2.26774121424901e-06	Estrogen signaling pathway: AKT3*
hsa05132__13	2.92161342740529e-07	DOWN	-5.12983086168455	2.32614899580277e-06	Salmonella infection: FOS
hsa04213__13	3.09998605182876e-07	DOWN	-5.11866084347729	2.44742596276733e-06	Longevity regulating pathway - multiple species: RPS6KB1*
hsa04932__28	3.09998605182876e-07	UP	5.11866084347729	2.44742596276733e-06	Non-alcoholic fatty liver disease (NAFLD): GSK3A
hsa04961__13	3.24061948640429e-07	DOWN	-5.11028332982185	2.54775063387182e-06	Endocrine and other factor-regulated calcium reabsorption: ATP2B1
hsa04932__31 133	3.28884232756279e-07	DOWN	-5.10749082527003	2.5748894722877e-06	Non-alcoholic fatty liver disease (NAFLD): PPARA RXRA
hsa04550__17	3.38740262814554e-07	DOWN	-5.1019058161664	2.64104960094833e-06	Signaling pathways regulating pluripotency of stem cells: AKT3
hsa04151__99	3.43774127057127e-07	UP	5.09911331161459	2.65823697424009e-06	PI3K-Akt signaling pathway: MYB
hsa04921__46	3.43774127057127e-07	DOWN	-5.09911331161459	2.65823697424009e-06	Oxytocin signaling pathway: C00942*
hsa04530__5 11 31	3.64641308080945e-07	DOWN	-5.08794329340733	2.80803695854137e-06	Tight junction: IGSF5 TJP1 MLLT4
hsa05217__19	3.70046105076183e-07	DOWN	-5.08515078885551	2.83802706709448e-06	Basal cell carcinoma: HHIP
hsa04068__45	3.75528177944869e-07	DOWN	-5.0823582843037	2.85675079497332e-06	FoxO signaling pathway: RBL2
hsa04621__43	3.75528177944869e-07	UP	5.0823582843037	2.85675079497332e-06	NOD-like receptor signaling pathway: MAPK1
hsa04666__41	3.81088588189402e-07	UP	5.07956577975188	2.88736071454793e-06	Fc gamma R-mediated phagocytosis: MARCKS
hsa05166__62 63	3.86728411250282e-07	UP	5.07677327520007	2.91832403509751e-06	HTLV-I infection: ANAPC10 CDC20
hsa04630__28	4.04135324471207e-07	UP	5.06839576154462	3.03748109872559e-06	Jak-STAT signaling pathway: CCND1
hsa04530__20 22	4.10103838089759e-07	DOWN	-5.06560325699281	3.05787742766134e-06	Tight junction: ACTB MYL12B
hsa04914__42	4.10103838089759e-07	DOWN	-5.06560325699281	3.05787742766134e-06	Progesterone-mediated oocyte maturation: ARAF
hsa04066__48	4.41244969766607e-07	DOWN	-5.05164073423373	3.26417046532069e-06	HIF-1 signaling pathway: PFKFB3
hsa04621__42	4.41244969766607e-07	UP	5.05164073423373	3.26417046532069e-06	NOD-like receptor signaling pathway: MAPK8
hsa04725__50	4.47741263514654e-07	DOWN	-5.04884822968191	3.29923856527073e-06	Cholinergic synapse: BCL2
hsa04919__102	4.88700081802958e-07	DOWN	-5.03209320237102	3.58698224104593e-06	Thyroid hormone signaling pathway: BMP4
hsa04722__85	4.95868845598547e-07	DOWN	-5.02930069781921	3.61138589488244e-06	Neurotrophin signaling pathway: BAX
hsa04724__68	4.95868845598547e-07	DOWN	-5.02930069781921	3.61138589488244e-06	Glutamatergic synapse: MAPK1
hsa05217__4	5.33260885114172e-07	DOWN	-5.01533817506013	3.86871506999818e-06	Basal cell carcinoma: PTCH1
hsa04152__68	5.41058819503233e-07	DOWN	-5.01254567050832	3.91019046864067e-06	AMPK signaling pathway: PPARGC1A**
hsa04024__113	5.48966642523124e-07	DOWN	-5.0097531659565	3.9521391620726e-06	cAMP signaling pathway: PTCH1
hsa04920__2	5.65117917707338e-07	DOWN	-5.00416815685287	4.03747744247942e-06	Adipocytokine signaling pathway: C00638
hsa05160__7	5.65117917707338e-07	UP	5.00416815685287	4.03747744247942e-06	Hepatitis C: IRF3
hsa04024__112	5.81726830380996e-07	DOWN	-4.99858314774924	4.12477250673922e-06	cAMP signaling pathway: GLI1
hsa05220__15	5.81726830380996e-07	DOWN	-4.99858314774924	4.12477250673922e-06	Chronic myeloid leukemia: MYC
hsa04390__76	5.90206773959978e-07	DOWN	-4.99579064319742	4.16916739951428e-06	Hippo signaling pathway: MYC
hsa04710__11	6.07525557302877e-07	DOWN	-4.99020563409379	4.27543266731126e-06	Circadian rhythm: CRY1
hsa04024__114	6.25333670094348e-07	DOWN	-4.98462062499016	4.38433569443015e-06	cAMP signaling pathway: HHIP
hsa04261__72	6.3442535378588e-07	DOWN	-4.98182812043835	4.43154364224412e-06	Adrenergic signaling in cardiomyocytes: ATP2B1
hsa04722__35	6.62471244225995e-07	DOWN	-4.9734506067829	4.57640980845825e-06	Neurotrophin signaling pathway: FOXO3
hsa04916__8	6.62471244225995e-07	DOWN	-4.9734506067829	4.57640980845825e-06	Melanogenesis: TYR*
hsa04933__26	6.62471244225995e-07	DOWN	-4.9734506067829	4.57640980845825e-06	AGE-RAGE signaling pathway in diabetic complications: IL6
hsa04610__44	6.81828249719488e-07	DOWN	-4.96786559767927	4.69287648799604e-06	Complement and coagulation cascades: C3
hsa04390__90	7.01729689887618e-07	UP	4.96228058857564	4.79472759017758e-06	Hippo signaling pathway: BBC3
hsa05219__27	7.01729689887618e-07	DOWN	-4.96228058857564	4.79472759017758e-06	Bladder cancer: RPS6KA5
hsa05166__114 112 113	7.32634868511343e-07	DOWN	-4.9539030749202	4.96975060625564e-06	HTLV-I infection: DLG1 CTNNB1 APC2
hsa05217__3	7.32634868511343e-07	DOWN	-4.9539030749202	4.96975060625564e-06	Basal cell carcinoma: GLI1
hsa04010__64	7.53962423419342e-07	UP	4.94831806581657	5.09602659570123e-06	MAPK signaling pathway: DDIT3
hsa05200__184	8.09930404672395e-07	DOWN	-4.93435554305749	5.45469258200513e-06	Pathways in cancer: GLI1
hsa04360__4	8.21594422026966e-07	DOWN	-4.93156303850567	5.51348542495953e-06	Axon guidance: GNAI1*
hsa04152__58	8.57565262949095e-07	UP	4.92318552485023	5.73439547715783e-06	AMPK signaling pathway: SCD
hsa04270__24	8.69889057274663e-07	DOWN	-4.92039302029841	5.79617566886203e-06	Vascular smooth muscle contraction: ACTA2
hsa04211__57	8.82383303090635e-07	DOWN	-4.9176005157466	5.85865097705761e-06	Longevity regulating pathway - mammal: ATG5
hsa04340__33	9.07892212710181e-07	DOWN	-4.91201550664297	5.98571743046467e-06	Hedgehog signaling pathway: HHIP*
hsa04916__15	9.07892212710181e-07	DOWN	-4.91201550664297	5.98571743046467e-06	Melanogenesis: MITF*
hsa04913__36	9.20911479889369e-07	DOWN	-4.90922300209115	6.02924275509451e-06	Ovarian steroidogenesis: CYP19A1
hsa04913__37	9.20911479889369e-07	DOWN	-4.90922300209115	6.02924275509451e-06	Ovarian steroidogenesis: CYP19A1*
hsa04723__9	9.34110405994195e-07	DOWN	-4.90643049753934	6.03159262152265e-06	Retrograde endocannabinoid signaling: PRKCA
hsa04725__20	9.34110405994195e-07	DOWN	-4.90643049753934	6.03159262152265e-06	Cholinergic synapse: PRKCA
hsa04726__18	9.34110405994195e-07	DOWN	-4.90643049753934	6.03159262152265e-06	Serotonergic synapse: PRKCA
hsa05200__186	9.34110405994195e-07	DOWN	-4.90643049753934	6.03159262152265e-06	Pathways in cancer: PTCH1*
hsa04360__3	9.47491365875616e-07	DOWN	-4.90363799298752	6.09704204274069e-06	Axon guidance: GNAI1
hsa04920__10	1.00288409398077e-06	UP	4.89246797478026	6.43146488938519e-06	Adipocytokine signaling pathway: PCK1
hsa04210__102	1.01721190433682e-06	DOWN	-4.88967547022845	6.50116043622068e-06	Apoptosis: PIDD1
hsa05166__26	1.03173663793813e-06	DOWN	-4.88688296567663	6.57163777181612e-06	HTLV-I infection: NFATC1
hsa04922__51	1.04646088650155e-06	DOWN	-4.88409046112482	6.64290542478517e-06	Glucagon signaling pathway: G6PC
hsa04550__53 64	1.13914546786385e-06	DOWN	-4.86733543381392	7.20691694988613e-06	Signaling pathways regulating pluripotency of stem cells: SMAD1 SMAD4
hsa04911__4	1.15534166541916e-06	DOWN	-4.86454292926211	7.28485566886778e-06	Insulin secretion: CACNA1C
hsa04921__34 35	1.17175931329558e-06	DOWN	-4.86175042471029	7.36366471465685e-06	Oxytocin signaling pathway: MYL9 ACTB
hsa04062__60	1.18840130960335e-06	UP	4.85895792015848	7.41862478652722e-06	Chemokine signaling pathway: GSK3A
hsa04620__39	1.18840130960335e-06	DOWN	-4.85895792015848	7.41862478652722e-06	Toll-like receptor signaling pathway: IL6
hsa04390__17 51	1.20527058853273e-06	DOWN	-4.85616541560666	7.47426876519143e-06	Hippo signaling pathway: YWHAQ YAP1
hsa04911__25	1.20527058853273e-06	DOWN	-4.85616541560666	7.47426876519143e-06	Insulin secretion: PRKCA
hsa05140__62	1.22237012077782e-06	DOWN	-4.85337291105485	7.55537321362346e-06	Leishmaniasis: C00584
hsa04110__43 83 84 85	1.29313149855393e-06	DOWN	-4.84220289284759	7.96653798617325e-06	Cell cycle: SMC1B SMC3 STAG1 RAD21
hsa04919__26	1.38713610361099e-06	DOWN	-4.82824037008851	8.46243096975668e-06	Thyroid hormone signaling pathway: THRB
hsa05161__30	1.38713610361099e-06	DOWN	-4.82824037008851	8.46243096975668e-06	Hepatitis B: MYC
hsa05218__8	1.38713610361099e-06	UP	4.82824037008851	8.46243096975668e-06	Melanoma: CDK4
hsa04921__56	1.44665733613952e-06	DOWN	-4.81986285643307	8.79698749063484e-06	Oxytocin signaling pathway: JUN
hsa04530__11 20 16	1.46703790447592e-06	DOWN	-4.81707035188125	8.86355055469536e-06	Tight junction: TJP1 ACTB CTTN
hsa04920__28	1.46703790447592e-06	DOWN	-4.81707035188125	8.86355055469536e-06	Adipocytokine signaling pathway: SLC2A1
hsa04620__20	1.48769439740365e-06	UP	4.81427784732943	8.95954414333799e-06	Toll-like receptor signaling pathway: IFNB1*
hsa04270__48	1.50863038729737e-06	DOWN	-4.81148534277762	9.02775954691641e-06	Vascular smooth muscle contraction: KCNMB2*
hsa05031__98	1.50863038729737e-06	DOWN	-4.81148534277762	9.02775954691641e-06	Amphetamine addiction: FOS
hsa05010__61	1.52984949047998e-06	UP	4.8086928382258	9.1256736273393e-06	Alzheimer's disease: GAPDH
hsa05200__217	1.57315172480577e-06	UP	4.80310782912217	9.35427876870267e-06	Pathways in cancer: E2F1*
hsa04068__47	1.595242312947e-06	DOWN	-4.80031532457036	9.42597580511765e-06	FoxO signaling pathway: GADD45G
hsa04068__54	1.595242312947e-06	DOWN	-4.80031532457036	9.42597580511765e-06	FoxO signaling pathway: GADD45G*
hsa04152__27	1.61763092941949e-06	DOWN	-4.79752282001854	9.46893618809728e-06	AMPK signaling pathway: ADIPOR1
hsa04810__8 79	1.61763092941949e-06	DOWN	-4.79752282001854	9.46893618809728e-06	Regulation of actin cytoskeleton: ARPC5 ACTB
hsa04810__8 82	1.61763092941949e-06	DOWN	-4.79752282001854	9.46893618809728e-06	Regulation of actin cytoskeleton: ARPC5 ACTB*
hsa04010__79	1.64032141803736e-06	UP	4.79473031546673	9.57193771581431e-06	MAPK signaling pathway: HSPB1
hsa04970__12	1.71018112161165e-06	UP	4.78635280181128	9.94870070436005e-06	Salivary secretion: BEST2
hsa04360__123	1.73418062975212e-06	DOWN	-4.78356029725947	9.99547669725226e-06	Axon guidance: ENAH
hsa05200__185	1.73418062975212e-06	DOWN	-4.78356029725947	9.99547669725226e-06	Pathways in cancer: HHIP
hsa05223__21	1.73418062975212e-06	DOWN	-4.78356029725947	9.99547669725226e-06	Non-small cell lung cancer: FOXO3*
hsa04020__64	1.75843980350063e-06	DOWN	-4.78076779270765	1.00428826467407e-05	Calcium signaling pathway: C01330*
hsa04020__12	1.75843980350063e-06	DOWN	-4.78076779270765	1.00428826467407e-05	Calcium signaling pathway: C01330
hsa04340__14	1.75843980350063e-06	DOWN	-4.78076779270765	1.00428826467407e-05	Hedgehog signaling pathway: PTCH1
hsa05168__122	1.7830249203288e-06	UP	4.77797528815584	1.01524358342358e-05	Herpes simplex infection: CASP3
hsa04931__40	1.80794016527339e-06	UP	4.77518278360402	1.02632011194825e-05	Insulin resistance: PRKCZ
hsa04924__23	1.85877803531017e-06	DOWN	-4.76959777450039	1.05200118323729e-05	Renin secretion: ITPR1
hsa04919__46	1.88470928788856e-06	DOWN	-4.76680526994858	1.0602900454918e-05	Thyroid hormone signaling pathway: ATP1B4
hsa05020__46	1.88470928788856e-06	DOWN	-4.76680526994858	1.0602900454918e-05	Prion diseases: PRKACA
hsa04911__54	1.96460518935495e-06	DOWN	-4.75842775629313	1.10193825396954e-05	Insulin secretion: RAB3A
hsa04270__46	2.01966604899341e-06	UP	4.7528427471895	1.12945015061268e-05	Vascular smooth muscle contraction: ITPR1*
hsa04931__124	2.04774938679675e-06	DOWN	-4.75005024263768	1.13837902301512e-05	Insulin resistance: FOXO1*
hsa05213__31	2.04774938679675e-06	DOWN	-4.75005024263768	1.13837902301512e-05	Endometrial cancer: MYC
hsa04914__29	2.07617790423565e-06	UP	4.74725773808587	1.14404518896159e-05	Progesterone-mediated oocyte maturation: CDK2
hsa04725__25	2.07620760742897e-06	UP	4.74725773808587	1.14404518896159e-05	Cholinergic synapse: CACNA1A
hsa04914__15	2.07620760742897e-06	UP	4.74725773808587	1.14404518896159e-05	Progesterone-mediated oocyte maturation: ANAPC10
hsa04211__23	2.16387965004332e-06	DOWN	-4.73888022443042	1.17512423769694e-05	Longevity regulating pathway - mammal: SOD2
hsa04750__59	2.16387965004332e-06	DOWN	-4.73888022443042	1.17512423769694e-05	Inflammatory mediator regulation of TRP channels: TRPV2
hsa05014__5	2.16387965004332e-06	UP	4.73888022443042	1.17512423769694e-05	Amyotrophic lateral sclerosis (ALS): TOMM40
hsa05161__207	2.16387965004332e-06	UP	4.73888022443042	1.17512423769694e-05	Hepatitis B: CDK2
hsa05161__219	2.16387965004332e-06	UP	4.73888022443042	1.17512423769694e-05	Hepatitis B: CDK2*
hsa04925__34	2.19388577737803e-06	DOWN	-4.73608771987861	1.18457223439463e-05	Aldosterone synthesis and secretion: STAR
hsa05200__192	2.19388577737803e-06	DOWN	-4.73608771987861	1.18457223439463e-05	Pathways in cancer: PTGS2
hsa05169__31	2.22429126920136e-06	DOWN	-4.73329521532679	1.19754822201414e-05	Epstein-Barr virus infection: MYC
hsa04022__48	2.28632070769055e-06	DOWN	-4.72771020622316	1.22045358231549e-05	cGMP-PKG signaling pathway: SLC8A2
hsa04664__30	2.28632070769055e-06	DOWN	-4.72771020622316	1.22045358231549e-05	Fc epsilon RI signaling pathway: PRKCA
hsa05162__23	2.28632070769055e-06	UP	4.72771020622316	1.22045358231549e-05	Measles: IRF3
hsa04261__36	2.38248897763619e-06	DOWN	-4.71933269256772	1.26818605920068e-05	Adrenergic signaling in cardiomyocytes: MAPK1
hsa04930__7	2.41539939740304e-06	DOWN	-4.7165401880159	1.28207216602269e-05	Type II diabetes mellitus: C00002
hsa04530__5 15	2.44874601581289e-06	DOWN	-4.71374768346409	1.29611091935561e-05	Tight junction: IGSF5 MPDZ
hsa05110__12	2.51676998649468e-06	UP	4.70816267436046	1.32465288644916e-05	Vibrio cholerae infection: C00080
hsa05120__35	2.51676998649468e-06	UP	4.70816267436046	1.32465288644916e-05	Epithelial cell signaling in Helicobacter pylori infection: C00080
hsa04066__29	2.65829957555599e-06	DOWN	-4.6969926561532	1.39523600627645e-05	HIF-1 signaling pathway: LDHA
hsa04520__44 49	2.69485784425831e-06	DOWN	-4.69420015160138	1.41048409174411e-05	Adherens junction: ACTB VCL
hsa04010__120	2.80745041769561e-06	DOWN	-4.68582263794594	1.46533314856946e-05	MAPK signaling pathway: NFATC1
hsa04726__45	2.84594789377117e-06	DOWN	-4.68303013339412	1.48131193695181e-05	Serotonergic synapse: TRPC1
hsa04066__60	2.88500520003669e-06	DOWN	-4.6802376288423	1.49749303062678e-05	HIF-1 signaling pathway: NOS3
hsa04922__37	2.96461330105995e-06	DOWN	-4.67465261973867	1.53457531479109e-05	Glucagon signaling pathway: PYGB
hsa04022__57	3.04632653499632e-06	DOWN	-4.66906761063504	1.56394742056232e-05	cGMP-PKG signaling pathway: C00144
hsa04390__75	3.04632653499632e-06	DOWN	-4.66906761063504	1.56394742056232e-05	Hippo signaling pathway: NKD1
hsa05134__70	3.04632653499632e-06	DOWN	-4.66906761063504	1.56394742056232e-05	Legionellosis: IL6
hsa04668__48	3.13019795317493e-06	UP	4.66348260153141	1.60262723542662e-05	TNF signaling pathway: CASP3
hsa04068__51	3.26017084511592e-06	DOWN	-4.65510508787597	1.65563811296563e-05	FoxO signaling pathway: BCL6
hsa04068__56	3.26017084511592e-06	DOWN	-4.65510508787597	1.65563811296563e-05	FoxO signaling pathway: BCL6*
hsa04916__10	3.26017084511592e-06	DOWN	-4.65510508787597	1.65563811296563e-05	Melanogenesis: CAMK2A
hsa04920__9	3.30463389961937e-06	UP	4.65231258332415	1.67369463541369e-05	Adipocytokine signaling pathway: G6PC
hsa04010__66	3.39531096787265e-06	UP	4.64672757422052	1.70582601835099e-05	MAPK signaling pathway: TP53
hsa04020__8	3.39531096787265e-06	DOWN	-4.64672757422052	1.70582601835099e-05	Calcium signaling pathway: PDE1A
hsa04915__21	3.39531096787265e-06	DOWN	-4.64672757422052	1.70582601835099e-05	Estrogen signaling pathway: CREB3
hsa04931__13	3.4415395516837e-06	DOWN	-4.64393506966871	1.71985447276959e-05	Insulin resistance: AKT2
hsa05221__26	3.4415395516837e-06	UP	4.64393506966871	1.71985447276959e-05	Acute myeloid leukemia: BAD
hsa04630__34	3.68188217254487e-06	DOWN	-4.62997254690963	1.83022661434175e-05	Jak-STAT signaling pathway: AOX1
hsa04919__45	3.68188217254487e-06	DOWN	-4.62997254690963	1.83022661434175e-05	Thyroid hormone signaling pathway: SLC9A1
hsa05161__100	3.73184439390103e-06	UP	4.62718004235782	1.85016770874407e-05	Hepatitis B: MMP9*
hsa05164__36	3.83372560441234e-06	DOWN	-4.62159503325419	1.895676423866e-05	Influenza A: IL33
hsa05217__5	3.88566077879678e-06	DOWN	-4.61880252870237	1.91631406912314e-05	Basal cell carcinoma: BMP2
hsa04932__35	4.10022521968871e-06	DOWN	-4.60763251049511	2.01683853083641e-05	Non-alcoholic fatty liver disease (NAFLD): PRKAG2
hsa04913__40	4.15561465692552e-06	DOWN	-4.60484000594329	2.03874672072142e-05	Ovarian steroidogenesis: HSD17B1
hsa04340__32	4.21172072888599e-06	DOWN	-4.60204750139148	2.06089147124395e-05	Hedgehog signaling pathway: PTCH1***
hsa04010__65	4.26855226429182e-06	UP	4.59925499683966	2.08327524794918e-05	MAPK signaling pathway: ELK4
hsa05161__213	4.32611819463441e-06	UP	4.59646249228785	2.1059005408596e-05	Hepatitis B: E2F1
hsa05210__9 11	4.38442755529294e-06	DOWN	-4.59366998773603	2.12876986470166e-05	Colorectal cancer: SMAD2 SMAD4
hsa04730__30	4.50331323530124e-06	DOWN	-4.5880849786324	2.1752507889797e-05	Long-term depression: C00025*
hsa05010__47	4.50331323530124e-06	DOWN	-4.5880849786324	2.1752507889797e-05	Alzheimer's disease: C00533
hsa03320__38	4.56390815506905e-06	DOWN	-4.58529247408059	2.19324384229533e-05	PPAR signaling pathway: SORBS1
hsa05205__17	4.56390815506905e-06	DOWN	-4.58529247408059	2.19324384229533e-05	Proteoglycans in cancer: AKT3
hsa04550__60	4.62528370830446e-06	UP	4.58249996952877	2.20581423550865e-05	Signaling pathways regulating pluripotency of stem cells: MAPK14
hsa04922__50	4.62528370830446e-06	DOWN	-4.58249996952877	2.20581423550865e-05	Glucagon signaling pathway: PCK1
hsa04972__23	4.62528370830446e-06	DOWN	-4.58249996952877	2.20581423550865e-05	Pancreatic secretion: KCNMA1
hsa04022__50	4.687449466993e-06	DOWN	-4.57970746497696	2.22980191100756e-05	cGMP-PKG signaling pathway: ATP2B1
hsa03320__53	4.75041511395525e-06	DOWN	-4.57691496042514	2.25404797957624e-05	PPAR signaling pathway: ADIPOQ
hsa04722__37	4.94420990047092e-06	UP	4.5685374467697	2.33421366909167e-05	Neurotrophin signaling pathway: NFKB1
hsa04924__49	4.94420990047092e-06	DOWN	-4.5685374467697	2.33421366909167e-05	Renin secretion: PDE1A
hsa04152__15	5.01047418763755e-06	DOWN	-4.56574494221788	2.35367024964274e-05	AMPK signaling pathway: FOXO1
hsa04520__69	5.01047418763755e-06	DOWN	-4.56574494221788	2.35367024964274e-05	Adherens junction: IQGAP1**
hsa04068__88	5.1455631572105e-06	DOWN	-4.56015993311425	2.41110054174527e-05	FoxO signaling pathway: FBXO32
hsa05100__55	5.21440870593936e-06	DOWN	-4.55736742856244	2.43728207921892e-05	Bacterial invasion of epithelial cells: ACTB*
hsa04510__44	5.42627734194299e-06	DOWN	-4.54898991490699	2.53001864156597e-05	Focal adhesion: BCL2
hsa04620__21	5.57207533142837e-06	UP	4.54340490580336	2.59156671974107e-05	Toll-like receptor signaling pathway: IFNA1
hsa04066__52	5.72161910109682e-06	DOWN	-4.53781989669973	2.64801041649284e-05	HIF-1 signaling pathway: FLT1
hsa05161__97	5.72161910109682e-06	DOWN	-4.53781989669973	2.64801041649284e-05	Hepatitis B: BCL2
hsa04810__82 83	5.79782415015146e-06	UP	4.53502739214791	2.67668589143356e-05	Regulation of actin cytoskeleton: ACTB ARPC5
hsa04360__82	5.9531587158075e-06	DOWN	-4.52944238304428	2.73495971320349e-05	Axon guidance: ILK
hsa04360__117	5.9531587158075e-06	DOWN	-4.52944238304428	2.73495971320349e-05	Axon guidance: CFL1*
hsa04261__34	6.03231188761752e-06	DOWN	-4.52664987849247	2.75783796516626e-05	Adrenergic signaling in cardiomyocytes: AKT3
hsa04932__96	6.03231188761752e-06	DOWN	-4.52664987849247	2.75783796516626e-05	Non-alcoholic fatty liver disease (NAFLD): IL6*
hsa04115__20	6.11247164751704e-06	UP	4.52385737394065	2.78770248196226e-05	p53 signaling pathway: RRM2B
hsa05231__48	6.27585974106093e-06	DOWN	-4.51827236483702	2.85528824538826e-05	Choline metabolism in cancer: WAS
hsa04724__52	6.35911282754186e-06	UP	4.51547986028521	2.88617705385294e-05	Glutamatergic synapse: CACNA1A
hsa04022__39	6.44342201074343e-06	DOWN	-4.51268735573339	2.91739517064745e-05	cGMP-PKG signaling pathway: KCNJ8
hsa04010__86	6.88126006354627e-06	UP	4.49872483297432	3.10814607197198e-05	MAPK signaling pathway: MAP4K2
hsa04972__21	6.97217829791916e-06	DOWN	-4.4959323284225	3.14166019707197e-05	Pancreatic secretion: KCNQ1
hsa04071__57	7.06424483856652e-06	UP	4.49313982387068	3.17553015590108e-05	Sphingolipid signaling pathway: BAX
hsa04310__16	7.15747346170312e-06	DOWN	-4.49034731931887	3.2097595786492e-05	Wnt signaling pathway: CAMK2A
hsa04550__69	7.34747284017861e-06	DOWN	-4.48476231021524	3.28711939683229e-05	Signaling pathways regulating pluripotency of stem cells: ID1
hsa04390__94	7.44427193274611e-06	DOWN	-4.48196980566342	3.32251471772683e-05	Hippo signaling pathway: GLI2
hsa04022__3	7.54228978557943e-06	DOWN	-4.47917730111161	3.35828495428999e-05	cGMP-PKG signaling pathway: MYL9
hsa04071__11	7.64154096965046e-06	DOWN	-4.47638479655979	3.39443392008823e-05	Sphingolipid signaling pathway: PRKCA
hsa04010__61	8.26378488435118e-06	UP	4.4596297692489	3.66218202775846e-05	MAPK signaling pathway: ATF4
hsa04726__10	8.37209136742407e-06	DOWN	-4.45683726469709	3.69276048811968e-05	Serotonergic synapse: PRKACA
hsa05213__11	8.37209136742407e-06	DOWN	-4.45683726469709	3.69276048811968e-05	Endometrial cancer: FOXO3
hsa04024__108	8.48175379923072e-06	UP	4.45404476014527	3.73236894350223e-05	cAMP signaling pathway: AMH
hsa04115__17	8.93428792573555e-06	UP	4.44287474193801	3.9223193954339e-05	p53 signaling pathway: TP73
hsa04630__36	9.05097538014196e-06	UP	4.4400822373862	3.96428502081276e-05	Jak-STAT signaling pathway: GFAP
hsa04913__21	9.16911818144621e-06	DOWN	-4.43728973283438	3.988141912717e-05	Ovarian steroidogenesis: CYP17A1
hsa04913__22	9.16911818144621e-06	DOWN	-4.43728973283438	3.988141912717e-05	Ovarian steroidogenesis: CYP17A1*
hsa05168__123	9.16911818144621e-06	UP	4.43728973283438	3.988141912717e-05	Herpes simplex infection: CYCS
hsa04151__105 62	1.00383382445579e-05	UP	4.41774220097167	4.33610058885615e-05	PI3K-Akt signaling pathway: CCND1 CDK2
hsa04520__17	1.00383382445579e-05	DOWN	-4.41774220097167	4.33610058885615e-05	Adherens junction: SNAI1
hsa05210__16	1.00383382445579e-05	DOWN	-4.41774220097167	4.33610058885615e-05	Colorectal cancer: MAPK8
hsa05200__216	1.01687600277651e-05	DOWN	-4.41494969641986	4.38236240646114e-05	Pathways in cancer: IL6
hsa04062__59	1.05698059072116e-05	DOWN	-4.40657218276441	4.52406954433953e-05	Chemokine signaling pathway: FOXO3
hsa04723__42	1.05698059072116e-05	DOWN	-4.40657218276441	4.52406954433953e-05	Retrograde endocannabinoid signaling: KCNJ3
hsa04723__50	1.05698059072116e-05	DOWN	-4.40657218276441	4.52406954433953e-05	Retrograde endocannabinoid signaling: KCNJ3*
hsa04022__46	1.0845513054713e-05	DOWN	-4.40098717366078	4.62102472331196e-05	cGMP-PKG signaling pathway: VASP
hsa04950__21	1.0845513054713e-05	UP	4.40098717366078	4.62102472331196e-05	Maturity onset diabetes of the young: PKLR
hsa04722__70	1.09859285532538e-05	UP	4.39819466910897	4.67026238723165e-05	Neurotrophin signaling pathway: ZNF274
hsa04022__49	1.11280787106826e-05	DOWN	-4.39540216455715	4.69879997693767e-05	cGMP-PKG signaling pathway: ATP1B4
hsa05132__8	1.11280787106826e-05	DOWN	-4.39540216455715	4.69879997693767e-05	Salmonella infection: TJP1
hsa05200__227	1.11280787106826e-05	DOWN	-4.39540216455715	4.69879997693767e-05	Pathways in cancer: FOXO1
hsa04976__38	1.12719838343656e-05	DOWN	-4.39260966000534	4.7488918441195e-05	Bile secretion: ABCC2
hsa04068__72	1.18655679978335e-05	DOWN	-4.38143964179808	4.98778574226601e-05	FoxO signaling pathway: SMAD2
hsa04915__40	1.21734344879455e-05	DOWN	-4.37585463269445	5.10577754527892e-05	Estrogen signaling pathway: CREB3**
hsa04024__109	1.26495664328873e-05	DOWN	-4.367477119039	5.29366042926399e-05	cAMP signaling pathway: BDNF
hsa04976__59	1.2812188363116e-05	DOWN	-4.36468461448719	5.33793834463304e-05	Bile secretion: ABCB4
hsa05211__40	1.2812188363116e-05	UP	4.36468461448719	5.33793834463304e-05	Renal cell carcinoma: PAK4
hsa04360__81	1.29768038801505e-05	DOWN	-4.36189210993537	5.35899219578084e-05	Axon guidance: FYN*
hsa04660__34	1.29768038801505e-05	DOWN	-4.36189210993537	5.35899219578084e-05	T cell receptor signaling pathway: FOS
hsa04933__58	1.29768038801505e-05	DOWN	-4.36189210993537	5.35899219578084e-05	AGE-RAGE signaling pathway in diabetic complications: CCL2
hsa05223__7	1.29768038801505e-05	DOWN	-4.36189210993537	5.35899219578084e-05	Non-small cell lung cancer: FOXO3
hsa04550__67	1.34828446140563e-05	DOWN	-4.35351459627992	5.55575987495872e-05	Signaling pathways regulating pluripotency of stem cells: MYC*
hsa04540__16 17	1.36556684096688e-05	DOWN	-4.35072209172811	5.61466103758594e-05	Gap junction: GJA1 GJA1**
hsa04151__102	1.38306040361011e-05	DOWN	-4.34792958717629	5.66180936466969e-05	PI3K-Akt signaling pathway: C8orf44-SGK3
hsa05132__86	1.38306040361011e-05	DOWN	-4.34792958717629	5.66180936466969e-05	Salmonella infection: MYH9
hsa05200__146 147	1.40075068542226e-05	DOWN	-4.34513708262448	5.68475659832507e-05	Pathways in cancer: RARB RXRA
hsa05222__14 15	1.40075068542226e-05	DOWN	-4.34513708262448	5.68475659832507e-05	Small cell lung cancer: RXRA RARB
hsa05223__29 34	1.40075068542226e-05	DOWN	-4.34513708262448	5.68475659832507e-05	Non-small cell lung cancer: RARB RXRA
hsa05169__104	1.40076759181719e-05	UP	4.34513708262448	5.68475659832507e-05	Epstein-Barr virus infection: IRF3
hsa05205__30	1.47378238212029e-05	DOWN	-4.33396706441722	5.9681833965604e-05	Proteoglycans in cancer: FLNA
hsa04340__15	1.55041757583556e-05	DOWN	-4.32279704620996	6.23818977514994e-05	Hedgehog signaling pathway: HHIP
hsa04919__87	1.55041757583556e-05	UP	4.32279704620996	6.23818977514994e-05	Thyroid hormone signaling pathway: BAD
hsa05160__15 16	1.55041757583556e-05	DOWN	-4.32279704620996	6.23818977514994e-05	Hepatitis C: TRAF6 RIPK1
hsa05200__188	1.57016176272279e-05	DOWN	-4.32000454165814	6.30413237640198e-05	Pathways in cancer: KLK3
hsa04660__40 41	1.59014550064002e-05	DOWN	-4.31721203710633	6.35719871426085e-05	T cell receptor signaling pathway: LAT GRAP2
hsa04660__41 46	1.59014550064002e-05	DOWN	-4.31721203710633	6.35719871426085e-05	T cell receptor signaling pathway: GRAP2 LCP2
hsa04115__39	1.63084265382954e-05	UP	4.3116270280027	6.50605806060661e-05	p53 signaling pathway: BAX
hsa04022__51	1.67253138094715e-05	DOWN	-4.30604201889907	6.64415743086615e-05	cGMP-PKG signaling pathway: GTF2I
hsa05221__13	1.67253138094715e-05	DOWN	-4.30604201889907	6.64415743086615e-05	Acute myeloid leukemia: NFKB1
hsa04740__21	1.71523450936687e-05	DOWN	-4.30045700979544	6.7994211879754e-05	Olfactory transduction: PDE1A
hsa04610__17	1.75897535786366e-05	UP	4.2948720006918	6.94351827190296e-05	Complement and coagulation cascades: PLG
hsa04933__56	1.75897535786366e-05	DOWN	-4.2948720006918	6.94351827190296e-05	AGE-RAGE signaling pathway in diabetic complications: NFATC1
hsa04530__13 45 20	1.78124235101914e-05	DOWN	-4.29207949613999	6.9873786587995e-05	Tight junction: EPB41 TJP2 ACTB
hsa05031__11	1.78124235101914e-05	UP	4.29207949613999	6.9873786587995e-05	Amphetamine addiction: GRIN3A
hsa05031__54	1.78124235101914e-05	UP	4.29207949613999	6.9873786587995e-05	Amphetamine addiction: GRIN3A*
hsa04064__55	1.89666498835111e-05	DOWN	-4.27811697338091	7.42465315231613e-05	NF-kappa B signaling pathway: CXCL12
hsa05160__66	1.92058891208926e-05	UP	4.2753244688291	7.50267477300565e-05	Hepatitis C: GSK3B
hsa03320__65	1.9448000775092e-05	DOWN	-4.27253196427728	7.58149241833981e-05	PPAR signaling pathway: ME1
hsa04152__52	2.01918977374286e-05	UP	4.26415445062184	7.8551916870866e-05	AMPK signaling pathway: PCK1
hsa04360__114	2.07027976461043e-05	DOWN	-4.25856944151821	8.03730511922107e-05	Axon guidance: RAF1
hsa04261__14 16	2.09628401199431e-05	UP	4.25577693696639	8.12147970832436e-05	Adrenergic signaling in cardiomyocytes: TNNI3 TPM1
hsa03320__43	2.12259904190131e-05	DOWN	-4.25298443241458	8.18965831567261e-05	PPAR signaling pathway: ILK
hsa04724__5 71	2.12259904190131e-05	UP	4.25298443241458	8.18965831567261e-05	Glutamatergic synapse: GRIN3A DLG4
hsa04151__24	2.14922836090395e-05	DOWN	-4.25019192786276	8.2584868918988e-05	PI3K-Akt signaling pathway: MYC
hsa05200__209	2.14922836090395e-05	DOWN	-4.25019192786276	8.2584868918988e-05	Pathways in cancer: FIGF**
hsa04152__61	2.17617551252394e-05	UP	4.24739942331095	8.32797105505596e-05	AMPK signaling pathway: RPS6KB1
hsa05168__29	2.17617551252394e-05	UP	4.24739942331095	8.32797105505596e-05	Herpes simplex infection: IKBKG
hsa04520__10	2.37401046903109e-05	UP	4.22785189144824	9.06659689290532e-05	Adherens junction: NLK
hsa04924__52	2.49462265646223e-05	UP	4.21668187324098	9.50790257909234e-05	Renin secretion: KCNJ2
hsa04630__27	2.52567414145708e-05	UP	4.21388936868916	9.58735699353102e-05	Jak-STAT signaling pathway: PIM1
hsa04664__25	2.52567414145708e-05	DOWN	-4.21388936868916	9.58735699353102e-05	Fc epsilon RI signaling pathway: MAPK14
hsa04068__43	2.55709305430894e-05	DOWN	-4.21109686413735	9.66756106447987e-05	FoxO signaling pathway: CDKN1A
hsa05133__46	2.55709305430894e-05	DOWN	-4.21109686413735	9.66756106447987e-05	Pertussis: CFL1
hsa04921__57	2.68652562284202e-05	DOWN	-4.19992684593009	0.000101365093279521	Oxytocin signaling pathway: FOS
hsa04024__101	2.78766323452293e-05	UP	4.19154933227464	0.000104970325003378	cAMP signaling pathway: HCN4
hsa04068__53	2.89241411253355e-05	DOWN	-4.1831718186192	0.000108479962424162	FoxO signaling pathway: SOD2
hsa05169__29	2.89241411253355e-05	DOWN	-4.1831718186192	0.000108479962424162	Epstein-Barr virus infection: FCER2
hsa05200__183	3.00089973124462e-05	DOWN	-4.17479430496375	0.000112324513844794	Pathways in cancer: BMP2
hsa05215__43	3.19030917856148e-05	DOWN	-4.16083178220467	0.0001187063097713	Prostate cancer: C05981
hsa04010__63	3.19035052871244e-05	UP	4.16083178220467	0.0001187063097713	MAPK signaling pathway: MAX
hsa04972__18	3.19035052871244e-05	DOWN	-4.16083178220467	0.0001187063097713	Pancreatic secretion: PRKCA
hsa04261__3	3.22958018386406e-05	DOWN	-4.15803927765286	0.000119928481531237	Adrenergic signaling in cardiomyocytes: RYR2
hsa04115__31	3.26926784777894e-05	DOWN	-4.15524677310104	0.000120924296968044	p53 signaling pathway: ADGRB1
hsa04910__9	3.26926784777894e-05	UP	4.15524677310104	0.000120924296968044	Insulin signaling pathway: ELK1
hsa04932__58	3.30941855463954e-05	UP	4.15245426854923	0.000122168908922745	Non-alcoholic fatty liver disease (NAFLD): BAX
hsa04068__40	3.39112949176287e-05	DOWN	-4.1468692594456	0.000124939849314165	FoxO signaling pathway: CCND1
hsa05215__25	3.43270004967156e-05	DOWN	-4.14407675489378	0.000126223941161113	Prostate cancer: FOXO1
hsa04210__119	3.51729755950508e-05	DOWN	-4.13849174579015	0.000128830450571346	Apoptosis: BCL2*
hsa05160__85	3.51729755950508e-05	UP	4.13849174579015	0.000128830450571346	Hepatitis C: BAD
hsa04810__48	3.5603351581107e-05	DOWN	-4.13569924123834	0.000130153108211868	Regulation of actin cytoskeleton: IQGAP2
hsa04360__21	3.87590101355781e-05	UP	4.11615170937563	0.000141413941834469	Axon guidance: PAK4
hsa04022__45	3.92309262688112e-05	DOWN	-4.11335920482382	0.0001428583536029	cGMP-PKG signaling pathway: CREB3
hsa04724__51	3.97082924891181e-05	UP	4.110566700272	0.000144316985661611	Glutamatergic synapse: ADRBK1
hsa04151__98	4.06796124943108e-05	UP	4.10498169116837	0.00014727744099578	PI3K-Akt signaling pathway: BCL2L1*
hsa04919__38	4.06796124943108e-05	DOWN	-4.10498169116837	0.00014727744099578	Thyroid hormone signaling pathway: TP53
hsa04066__64	4.11736864276949e-05	DOWN	-4.10218918661655	0.000147926112423783	HIF-1 signaling pathway: LTBR
hsa04520__44 47	4.11736864276949e-05	DOWN	-4.10218918661655	0.000147926112423783	Adherens junction: ACTB TJP1
hsa05161__188	4.11736864276949e-05	UP	4.10218918661655	0.000147926112423783	Hepatitis B: IFNB1
hsa05215__34	4.11736864276949e-05	UP	4.10218918661655	0.000147926112423783	Prostate cancer: BAD
hsa04660__35	4.16734507561441e-05	DOWN	-4.09939668206474	0.000149435904524418	T cell receptor signaling pathway: NFATC1
hsa04360__89	4.5336384845e-05	DOWN	-4.07984915020203	0.000161952599094591	Axon guidance: CAMK2A
hsa05205__304	4.5336384845e-05	DOWN	-4.07984915020203	0.000161952599094591	Proteoglycans in cancer: MAPK1*****
hsa04931__135	4.58839424755308e-05	UP	4.07705664565022	0.000163597586169872	Insulin resistance: SREBF1**
hsa04064__3	4.69979276450544e-05	DOWN	-4.07147163654659	0.000166935928251526	NF-kappa B signaling pathway: BCL2
hsa04360__145	4.69979276450544e-05	DOWN	-4.07147163654659	0.000166935928251526	Axon guidance: ABLIM3
hsa04012__31	4.75644905986605e-05	UP	4.06867913199477	0.00016831201098848	ErbB signaling pathway: BAD
hsa05212__8	4.75644905986605e-05	DOWN	-4.06867913199477	0.00016831201098848	Pancreatic cancer: NFKB1
hsa04630__30	5.04957785303463e-05	UP	4.0547166092357	0.000178014198608857	Jak-STAT signaling pathway: CDKN1A
hsa04668__47	5.04957785303463e-05	UP	4.0547166092357	0.000178014198608857	TNF signaling pathway: CASP7
hsa04071__24	5.17155726267669e-05	DOWN	-4.04913160013207	0.000181972960609916	Sphingolipid signaling pathway: PTEN
hsa05223__9	5.23358911194559e-05	UP	4.04633909558025	0.000183811475539173	Non-small cell lung cancer: BAD
hsa04623__9	5.29632561505547e-05	UP	4.04354659102844	0.000185667832662112	Cytosolic DNA-sensing pathway: IKBKE
hsa05215__12	5.3597742817768e-05	DOWN	-4.04075408647662	0.000187542195073717	Prostate cancer: KLK3
hsa04151__100	5.42394269595838e-05	DOWN	-4.0379615819248	0.0001887331171427	PI3K-Akt signaling pathway: PRKCA
hsa04950__5	5.42394269595838e-05	DOWN	-4.0379615819248	0.0001887331171427	Maturity onset diabetes of the young: GCK
hsa05145__67	5.42394269595838e-05	UP	4.0379615819248	0.0001887331171427	Toxoplasmosis: BAD
hsa04022__71	5.48883851618961e-05	UP	4.03516907737299	0.000190638217595569	cGMP-PKG signaling pathway: PPIF
hsa05216__11	5.62084338687078e-05	DOWN	-4.02958406826936	0.00019486281778469	Thyroid cancer: MYC
hsa04510__42	5.75585168283678e-05	UP	4.02399905916573	0.000199175788435549	Focal adhesion: BIRC2
hsa04022__43	5.89392743220805e-05	DOWN	-4.0184140500621	0.000203578853770569	cGMP-PKG signaling pathway: MAPK1
hsa04919__11	6.10693570220967e-05	DOWN	-4.01003653640665	0.000210549214393614	Thyroid hormone signaling pathway: CTNNB1
hsa04931__144	6.55500899536495e-05	DOWN	-3.99328150909576	0.000225171149950471	Insulin resistance: C00533*
hsa05213__12	6.55500899536495e-05	UP	3.99328150909576	0.000225171149950471	Endometrial cancer: BAD
hsa04210__83	6.63264851690272e-05	DOWN	-3.99048900454395	0.000227008134121315	Apoptosis: TP53*
hsa04933__63	6.63264851690272e-05	DOWN	-3.99048900454395	0.000227008134121315	AGE-RAGE signaling pathway in diabetic complications: SELE
hsa04211__39	6.71115774302775e-05	UP	3.98769649999213	0.000228861441000892	Longevity regulating pathway - mammal: TP53*
hsa04933__21	6.71115774302775e-05	DOWN	-3.98769649999213	0.000228861441000892	AGE-RAGE signaling pathway in diabetic complications: SMAD4
hsa04380__20	6.79054579694495e-05	UP	3.98490399544032	0.000231149194790934	Osteoclast differentiation: MAP2K1
hsa04024__24	6.87082189020081e-05	DOWN	-3.9821114908885	0.000233458848674274	cAMP signaling pathway: PLN
hsa04270__28	6.95199532345541e-05	DOWN	-3.97931898633668	0.000235790599508533	Vascular smooth muscle contraction: KCNMB2
hsa04360__35	7.03407548725988e-05	DOWN	-3.97652648178487	0.000237716328067649	Axon guidance: ROCK1*
hsa05162__13	7.03407548725988e-05	UP	3.97652648178487	0.000237716328067649	Measles: IRF7
hsa04014__55	7.11707186284012e-05	DOWN	-3.97373397723305	0.000240089372177318	Ras signaling pathway: MLLT4
hsa03320__26	7.37165444923566e-05	DOWN	-3.96535646357761	0.000247787812345506	PPAR signaling pathway: CPT2
hsa04340__26	7.37165444923566e-05	DOWN	-3.96535646357761	0.000247787812345506	Hedgehog signaling pathway: PTCH1**
hsa04360__125	7.45841232542857e-05	DOWN	-3.96256395902579	0.000250256370705005	Axon guidance: ENAH*
hsa05218__14	8.28388396218013e-05	UP	3.93743141805946	0.000277458430747531	Melanoma: BAD
hsa04213__2	8.57771928208862e-05	DOWN	-3.92905390440401	0.000286788870659155	Longevity regulating pathway - multiple species: RPS6KB1
hsa04310__22	8.779022292516e-05	DOWN	-3.92346889530038	0.000292479388455049	Wnt signaling pathway: ROCK2
hsa04012__21	8.77905136182267e-05	UP	3.92346889530038	0.000292479388455049	ErbB signaling pathway: GSK3B
hsa04910__39	8.98484222735352e-05	UP	3.91788388619675	0.000297751649827112	Insulin signaling pathway: BAD
hsa05200__121 122	8.98484222735352e-05	DOWN	-3.91788388619675	0.000297751649827112	Pathways in cancer: SMAD2 SMAD4
hsa05212__38 39	8.98484222735352e-05	DOWN	-3.91788388619675	0.000297751649827112	Pancreatic cancer: SMAD2 SMAD4
hsa05205__22	9.30209088190525e-05	DOWN	-3.9095063725413	0.000307722337448943	Proteoglycans in cancer: PPP1R12A
hsa05214__35	9.51943586116213e-05	UP	3.90392136343767	0.000314358874923087	Glioma: E2F1
hsa04390__13	9.62989817675719e-05	UP	3.90112885888586	0.00031744874866889	Hippo signaling pathway: BIRC5
hsa05211__43	9.74157000235032e-05	DOWN	-3.89833635433404	0.00032000716843385	Renal cell carcinoma: RAP1A
hsa05220__4	9.74157000235032e-05	DOWN	-3.89833635433404	0.00032000716843385	Chronic myeloid leukemia: PTPN11
hsa05220__19 41	9.85446370114554e-05	DOWN	-3.89554384978223	0.00032315073812308	Chronic myeloid leukemia: SMAD4 SMAD3
hsa03320__44	0.000100839667527003	DOWN	-3.8899588406786	0.000330100584117141	PPAR signaling pathway: FABP1
hsa04923__38	0.000103185085769405	DOWN	-3.88437383157497	0.000337190915062108	Regulation of lipolysis in adipocytes: PDE3B
hsa04360__19	0.00010803123082956	UP	3.87320381336771	0.000352414379737403	Axon guidance: CDC42
hsa04723__10	0.000110534079097431	UP	3.86761880426408	0.000359331374782132	Retrograde endocannabinoid signaling: CACNA1A
hsa04723__21	0.000110534079097431	UP	3.86761880426408	0.000359331374782132	Retrograde endocannabinoid signaling: CACNA1A*
hsa04972__39	0.000111805921008196	DOWN	-3.86482629971226	0.00036221263030069	Pancreatic secretion: KCNMA1*
hsa05212__34	0.000111805921008196	UP	3.86482629971226	0.00036221263030069	Pancreatic cancer: E2F1
hsa05152__82	0.000113091558646932	DOWN	-3.86203379516045	0.000365747054556944	Tuberculosis: IL6
hsa05166__39	0.000115704780436717	UP	3.85644878605682	0.000373555468110982	HTLV-I infection: RRAS2
hsa03320__33	0.000117032647496787	DOWN	-3.853656281505	0.000375263386768707	PPAR signaling pathway: CYP7A1
hsa04064__129	0.000117032647496787	DOWN	-3.853656281505	0.000375263386768707	NF-kappa B signaling pathway: PTGS2
hsa04919__88	0.000117032647496787	DOWN	-3.853656281505	0.000375263386768707	Thyroid hormone signaling pathway: FOXO1
hsa04933__52	0.000117032647496787	DOWN	-3.853656281505	0.000375263386768707	AGE-RAGE signaling pathway in diabetic complications: FOXO1
hsa04014__44	0.000119731611067204	DOWN	-3.84807127240137	0.00038261172992394	Ras signaling pathway: ETS1
hsa04970__21	0.000119731611067204	DOWN	-3.84807127240137	0.00038261172992394	Salivary secretion: ITPR1
hsa04015__63	0.000122489185585582	DOWN	-3.84248626329774	0.000389436852310166	Rap1 signaling pathway: GNAI1
hsa04068__67	0.000122489185585582	DOWN	-3.84248626329774	0.000389436852310166	FoxO signaling pathway: GABARAP
hsa05142__36	0.000122489185585582	DOWN	-3.84248626329774	0.000389436852310166	Chagas disease (American trypanosomiasis): SMAD2
hsa04071__68	0.000123890321385394	DOWN	-3.83969375874592	0.000393226205883707	Sphingolipid signaling pathway: NFKB1
hsa05200__224	0.000126738040886599	DOWN	-3.83410874964229	0.000400910402063837	Pathways in cancer: MYC***
hsa05221__12	0.000126738040886599	DOWN	-3.83410874964229	0.000400910402063837	Acute myeloid leukemia: MYC
hsa04668__120	0.00013565587064098	UP	3.8173537223314	0.000428398959553615	TNF signaling pathway: DNM1L
hsa05205__318	0.000137198469506624	DOWN	-3.81456121777959	0.000432543496984808	Proteoglycans in cancer: HSPB2
hsa04066__58	0.000140333373073638	DOWN	-3.80897620867596	0.000440947170577534	HIF-1 signaling pathway: EDN1
hsa04920__43	0.000140333373073638	DOWN	-3.80897620867596	0.000440947170577534	Adipocytokine signaling pathway: C00162
hsa04390__14	0.000143535655221837	DOWN	-3.80339119957233	0.000450256254026432	Hippo signaling pathway: AREG
hsa05130__28	0.00014680666208955	DOWN	-3.7978061904687	0.00045898455585069	Pathogenic Escherichia coli infection: ROCK1
hsa05166__132 136	0.00014680666208955	UP	3.7978061904687	0.00045898455585069	HTLV-I infection: CREBBP TP53
hsa04666__42	0.000148468364665276	UP	3.79501368591688	0.000463408732900422	Fc gamma R-mediated phagocytosis: MYO10
hsa04014__70	0.000150147764371513	UP	3.79222118136507	0.000466326692981939	Ras signaling pathway: RIN1*
hsa04151__32	0.000150147764371513	UP	3.79222118136507	0.000466326692981939	PI3K-Akt signaling pathway: BCL2L1
hsa05321__55	0.000150147764371513	DOWN	-3.79222118136507	0.000466326692981939	Inflammatory bowel disease (IBD): IL4*
hsa04530__20 62	0.00015184503644717	DOWN	-3.78942867681325	0.00047004419025409	Tight junction: ACTB SHROOM1
hsa04933__23	0.00015184503644717	DOWN	-3.78942867681325	0.00047004419025409	AGE-RAGE signaling pathway in diabetic complications: F3
hsa04066__55	0.000157045863126415	DOWN	-3.7810511631578	0.000484547088365407	HIF-1 signaling pathway: ANGPT1
hsa04068__39	0.000157045863126415	UP	3.7810511631578	0.000484547088365407	FoxO signaling pathway: CCNB3
hsa04723__40	0.000158816408953677	DOWN	-3.77825865860599	0.000487607896117581	Retrograde endocannabinoid signaling: GRIA1
hsa04724__4	0.000158816408953677	DOWN	-3.77825865860599	0.000487607896117581	Glutamatergic synapse: GRIA1
hsa05031__12	0.000158816408953677	DOWN	-3.77825865860599	0.000487607896117581	Amphetamine addiction: GRIA1
hsa04014__30	0.000162414003316265	DOWN	-3.77267364950236	0.000497029173015086	Ras signaling pathway: C01245
hsa04622__44	0.000162414003316265	UP	3.77267364950236	0.000497029173015086	RIG-I-like receptor signaling pathway: MAPK8
hsa05205__256	0.000166088175875366	DOWN	-3.76708864039873	0.000506622861152293	Proteoglycans in cancer: ACTB
hsa05212__31	0.000166088175875366	UP	3.76708864039873	0.000506622861152293	Pancreatic cancer: RAC1*
hsa04064__116	0.000167954450731056	DOWN	-3.76429613584691	0.000510657626090054	NF-kappa B signaling pathway: GADD45B
hsa05205__103	0.000167954450731056	DOWN	-3.76429613584691	0.000510657626090054	Proteoglycans in cancer: CCND1
hsa04066__5	0.000169840439626917	DOWN	-3.7615036312951	0.00051555765114536	HIF-1 signaling pathway: VEGFA
hsa04010__68	0.000171746335946089	UP	3.75871112674328	0.000520502202004356	MAPK signaling pathway: ATF2
hsa04066__63	0.000175618633046197	DOWN	-3.75312611763965	0.000528825979958019	HIF-1 signaling pathway: TIMP1*
hsa04066__57	0.000175618633046197	DOWN	-3.75312611763965	0.000528825979958019	HIF-1 signaling pathway: TIMP1
hsa04950__20	0.000175618633046197	UP	3.75312611763965	0.000528825979958019	Maturity onset diabetes of the young: NKX6-1
hsa05016__52	0.000175618633046197	UP	3.75312611763965	0.000528825979958019	Huntington's disease: CASP3
hsa04066__54	0.00017957292392543	DOWN	-3.74754110853602	0.000539005629482241	HIF-1 signaling pathway: SERPINE1
hsa05016__22 9	0.00017957292392543	UP	3.74754110853602	0.000539005629482241	Huntington's disease: DLG4 HTT
hsa05164__68	0.000183610818804369	UP	3.74195609943239	0.000550246775970349	Influenza A: EIF2S1
hsa04610__57	0.000185661628793098	UP	3.73916359488058	0.000555506688697819	Complement and coagulation cascades: PLAUR
hsa04666__50 52	0.000189828011901128	DOWN	-3.73357858577695	0.000566169578352728	Fc gamma R-mediated phagocytosis: DNM2 AMPH
hsa05168__10	0.000189828011901128	DOWN	-3.73357858577695	0.000566169578352728	Herpes simplex infection: FOS
hsa05205__129	0.000191944005764619	DOWN	-3.73078608122513	0.000570668966505886	Proteoglycans in cancer: AKT3*
hsa05211__46	0.000191944005764619	DOWN	-3.73078608122513	0.000570668966505886	Renal cell carcinoma: AKT3
hsa04115__52 53	0.000194082151437173	UP	3.72799357667332	0.000576114316825353	p53 signaling pathway: CDK4 CCND1
hsa03320__57	0.000200631659357162	DOWN	-3.71961606301787	0.000594616542479663	PPAR signaling pathway: APOC3
hsa04670__15	0.000202860278750096	DOWN	-3.71682355846605	0.000598390947142771	Leukocyte transendothelial migration: PECAM1
hsa04010__15	0.000202860581867986	DOWN	-3.71682355846605	0.000598390947142771	MAPK signaling pathway: NFKB1
hsa04152__57	0.000202860581867986	UP	3.71682355846605	0.000598390947142771	AMPK signaling pathway: ACACA*
hsa04068__66	0.000205112750594924	DOWN	-3.71403105391424	0.000603140623423886	FoxO signaling pathway: BNIP3
hsa05205__337	0.000205112750594924	DOWN	-3.71403105391424	0.000603140623423886	Proteoglycans in cancer: CTNNB1**
hsa04270__17	0.000207388390235252	DOWN	-3.71123854936242	0.000608879351956311	Vascular smooth muscle contraction: ITPR1
hsa04022__44	0.00020968772745996	DOWN	-3.70844604481061	0.000614669641025374	cGMP-PKG signaling pathway: BAD
hsa04742__46	0.000212010045951501	DOWN	-3.70565354025879	0.000620509153182042	Taste transduction: P2RY1
hsa04550__47	0.000216730221276493	DOWN	-3.70006853115516	0.000632354170463556	Signaling pathways regulating pluripotency of stem cells: CTNNB1*
hsa04620__66	0.000216730221276493	UP	3.70006853115516	0.000632354170463556	Toll-like receptor signaling pathway: CASP8
hsa05152__51	0.000219126655558006	UP	3.69727602660335	0.000638355016734098	Tuberculosis: CASP3
hsa05031__55	0.000223994346202041	DOWN	-3.69169101749972	0.000651525350640301	Amphetamine addiction: GRIA1*
hsa04370__38	0.000226466082319941	UP	3.6888985129479	0.000655669905514899	VEGF signaling pathway: BAD
hsa04722__46	0.000226466082319941	DOWN	-3.6888985129479	0.000655669905514899	Neurotrophin signaling pathway: ATF4*
hsa05014__32 34	0.000226466082319941	DOWN	-3.6888985129479	0.000655669905514899	Amyotrophic lateral sclerosis (ALS): NEFM PRPH
hsa05218__21	0.000228963402291872	UP	3.68610600839609	0.000660863645017554	Melanoma: RB1
hsa05220__40	0.000228963402291872	UP	3.68610600839609	0.000660863645017554	Chronic myeloid leukemia: RB1
hsa05168__79	0.000231486551249274	UP	3.68331350384427	0.000667121518094151	Herpes simplex infection: EIF2S1
hsa04620__18	0.00023661132731448	UP	3.67772849474064	0.000679805327253683	Toll-like receptor signaling pathway: CXCL11
hsa05152__98	0.00023661132731448	UP	3.67772849474064	0.000679805327253683	Tuberculosis: IL23A
hsa04723__73	0.000241842414467637	DOWN	-3.67214348563701	0.000692716306074222	Retrograde endocannabinoid signaling: MAPK14*
hsa04723__68	0.000241842414467637	DOWN	-3.67214348563701	0.000692716306074222	Retrograde endocannabinoid signaling: MAPK14
hsa04925__5	0.000247181851531022	DOWN	-3.66655847653338	0.000706932570817033	Aldosterone synthesis and secretion: KCNK3
hsa04630__35	0.000252631712727169	DOWN	-3.66097346742975	0.000721420954733054	Jak-STAT signaling pathway: MTOR
hsa05210__31	0.000275578152530956	DOWN	-3.63863343101523	0.000784562649402524	Colorectal cancer: BCL2
hsa05215__39	0.000275578152530956	UP	3.63863343101523	0.000784562649402524	Prostate cancer: RB1
hsa04310__20	0.000278580027722792	DOWN	-3.63584092646341	0.000790712797720733	Wnt signaling pathway: MAPK8
hsa04950__7	0.000278580027722792	UP	3.63584092646341	0.000790712797720733	Maturity onset diabetes of the young: FOXA3
hsa04620__48	0.00028161252466666	UP	3.6330484219116	0.000798114530691787	Toll-like receptor signaling pathway: CD80
hsa04621__21 30	0.000300466890932355	DOWN	-3.61629339460071	0.000848988403100595	NOD-like receptor signaling pathway: NLRP3 PYCARD
hsa04922__78	0.000300466890932355	DOWN	-3.61629339460071	0.000848988403100595	Glucagon signaling pathway: ACACA
hsa04152__87	0.00030372195638827	DOWN	-3.61350089004889	0.000855612527816432	AMPK signaling pathway: CD36
hsa05205__431	0.00030372195638827	DOWN	-3.61350089004889	0.000855612527816432	Proteoglycans in cancer: CDKN1A*
hsa04012__47	0.000310331394091913	DOWN	-3.60791588094526	0.000872923187872313	ErbB signaling pathway: PRKCA
hsa04520__58	0.00031926944411298	UP	3.40127054411094	0.000896722399833018	Adherens junction: CDH1*
hsa05161__66 67	0.00032049848644621	DOWN	-3.59953836728982	0.000898830829899146	Hepatitis B: NFKB1 NFKBIA
hsa04010__119	0.000323956230214166	DOWN	-3.596745862738	0.000907174003833708	MAPK signaling pathway: NFATC3
hsa04115__22	0.000341774841438586	UP	3.58278333997892	0.000955647212891523	p53 signaling pathway: STEAP3
hsa05164__31 32 33	0.000364364444467755	DOWN	-3.56602831266803	0.00101428966155437	Influenza A: NLRP3 PYCARD CASP1
hsa04010__57	0.000364366961974028	UP	3.56602831266803	0.00101428966155437	MAPK signaling pathway: NLK
hsa04390__74	0.000364366961974028	DOWN	-3.56602831266803	0.00101428966155437	Hippo signaling pathway: AXIN1
hsa04340__13	0.000368265423117463	DOWN	-3.56323580811622	0.00102362534029247	Hedgehog signaling pathway: GLI1*
hsa04750__62	0.000380187703113423	UP	3.55485829446077	0.00105367020039552	Inflammatory mediator regulation of TRP channels: TRPM8*
hsa04950__18	0.00038019605953601	UP	3.55485829446077	0.00105367020039552	Maturity onset diabetes of the young: SLC2A2
hsa05160__53	0.000388349483781085	UP	3.54927328535714	0.00107310100003626	Hepatitis C: EIF2S1
hsa05162__74	0.000388349483781085	UP	3.54927328535714	0.00107310100003626	Measles: EIF2S1
hsa05200__76	0.000392487198378352	UP	3.54648078080533	0.00108135402603068	Pathways in cancer: RAC1
hsa05223__28	0.000392487198378352	UP	3.54648078080533	0.00108135402603068	Non-small cell lung cancer: RB1
hsa04066__50	0.000400886500366312	DOWN	-3.5408957717017	0.00109965800611431	HIF-1 signaling pathway: TF
hsa04066__30	0.000400886500366312	DOWN	-3.5408957717017	0.00109965800611431	HIF-1 signaling pathway: PDK1
hsa04380__68	0.000400886500366312	DOWN	-3.5408957717017	0.00109965800611431	Osteoclast differentiation: TGFBR1
hsa04012__29	0.000405148844121592	DOWN	-3.53810326714988	0.00110972985146424	ErbB signaling pathway: STAT5A*
hsa04310__31	0.000409453492470944	UP	3.53531076259807	0.00111988808202752	Wnt signaling pathway: MMP7
hsa05142__21	0.000413800831394712	DOWN	-3.53251825804625	0.00113013337527713	Chagas disease (American trypanosomiasis): TICAM1
hsa05140__43	0.000427102898930783	UP	3.5241407443908	0.00116476973452967	Leishmaniasis: MAPK14
hsa04622__11	0.000431624923464496	UP	3.52134823983899	0.00117369498001417	RIG-I-like receptor signaling pathway: IRF7
hsa05110__52	0.000431624923464496	DOWN	-3.52134823983899	0.00117369498001417	Vibrio cholerae infection: ADCY3
hsa04670__14	0.000436191616301193	UP	3.51855573528717	0.00118268982255403	Leukocyte transendothelial migration: SIPA1
hsa04971__55	0.000436191616301193	DOWN	-3.51855573528717	0.00118268982255403	Gastric acid secretion: MYLK4
hsa04726__38	0.00044546063124882	DOWN	-3.51297072618354	0.00120608144973564	Serotonergic synapse: PLA2G4B
hsa04390__77	0.00045016377379924	DOWN	-3.51017822163173	0.00121531283185168	Hippo signaling pathway: CCND1
hsa04510__24 69	0.00045016377379924	DOWN	-3.51017822163173	0.00121531283185168	Focal adhesion: ZYX ACTB
hsa05020__62	0.000459709405163732	DOWN	-3.5045932125281	0.00123930268623049	Prion diseases: NOTCH1
hsa04917__31	0.000464552734523836	DOWN	-3.50180070797628	0.0012487762348645	Prolactin signaling pathway: GALT
hsa05166__120	0.000464552734523836	UP	3.50180070797628	0.0012487762348645	HTLV-I infection: E2F1
hsa04340__51	0.00046944363903303	DOWN	-3.49900820342447	0.00126012085391866	Hedgehog signaling pathway: CCND1*
hsa04024__111	0.00047936989218689	DOWN	-3.49342319432084	0.00128493013897171	cAMP signaling pathway: JUN
hsa04933__28	0.000484406108840352	DOWN	-3.49063068976902	0.00129657988391883	AGE-RAGE signaling pathway in diabetic complications: VCAM1
hsa03320__47	0.000494626918566631	DOWN	-3.48504568066539	0.00132205402558563	PPAR signaling pathway: PLTP
hsa04152__60	0.000499812400744474	UP	3.48225317611358	0.00133212411489201	AMPK signaling pathway: EEF2
hsa04510__20 4 5	0.000499812400744474	DOWN	-3.48225317611358	0.00133212411489201	Focal adhesion: VASP ITGB1 ITGA11
hsa04910__20	0.000505048533146575	UP	3.47946067156176	0.00134417307901192	Insulin signaling pathway: PKLR
hsa04380__48	0.000521065384905835	DOWN	-3.47108315790632	0.00138483996921933	Osteoclast differentiation: NFATC1
hsa04540__18 19	0.000532004948620104	DOWN	-3.46549814880269	0.00140793985698194	Gap junction: GJA1 GJA1***
hsa04728__32	0.000532004948620104	DOWN	-3.46549814880269	0.00140793985698194	Dopaminergic synapse: CREB3
hsa05161__126	0.000532004948620104	DOWN	-3.46549814880269	0.00140793985698194	Hepatitis B: MYC*
hsa04024__92	0.000537554633734052	UP	3.46270564425087	0.00142062609955877	cAMP signaling pathway: GRIN3A
hsa04920__6	0.000554529021049912	DOWN	-3.45432813059542	0.00146342700920335	Adipocytokine signaling pathway: PTPN11
hsa04064__133	0.000566121230931847	DOWN	-3.44874312149179	0.00149192397324115	NF-kappa B signaling pathway: CXCL2
hsa05014__33 34	0.000572001594048173	DOWN	-3.44595061693998	0.00150530951710997	Amyotrophic lateral sclerosis (ALS): NEFH PRPH
hsa04610__52	0.000577938792861945	UP	3.44315811238816	0.00151668574272011	Complement and coagulation cascades: CPB2
hsa04726__64	0.000577938792861945	UP	3.44315811238816	0.00151668574272011	Serotonergic synapse: CASP3
hsa04727__47	0.00059609644919197	DOWN	-3.43478059873272	0.00156215512975134	GABAergic synapse: CACNA1A*
hsa04261__20	0.000608495052032879	DOWN	-3.42919558962909	0.00159242646625318	Adrenergic signaling in cardiomyocytes: ATP1B4
hsa05205__195	0.00063401543335809	DOWN	-3.41802557142183	0.00165690542319868	Proteoglycans in cancer: CDKN1A
hsa04261__62	0.000640549292940645	DOWN	-3.41523306687001	0.00166933720032659	Adrenergic signaling in cardiomyocytes: BCL2
hsa04530__5 10	0.000640549292940645	DOWN	-3.41523306687001	0.00166933720032659	Tight junction: IGSF5 MAGI1
hsa04022__66	0.00064714573862517	UP	3.4124405623182	0.00168186285321811	cGMP-PKG signaling pathway: PDE3A
hsa04750__53	0.00064714573862517	UP	3.4124405623182	0.00168186285321811	Inflammatory mediator regulation of TRP channels: TRPM8
hsa04012__56	0.000674168397588871	DOWN	-3.40127054411094	0.00174725850906136	ErbB signaling pathway: JUN
hsa04114__56	0.000674168397588871	DOWN	-3.40127054411094	0.00174725850906136	Oocyte meiosis: REC8
hsa04210__63	0.000688069683575908	DOWN	-3.3956855350073	0.00177838092907721	Apoptosis: FAS*
hsa04621__4 7 8	0.000688069683575908	UP	3.3956855350073	0.00177838092907721	NOD-like receptor signaling pathway: IKBKG CHUK IKBKB
hsa04919__91	0.000695119803771656	DOWN	-3.39289303045549	0.00178921933053006	Thyroid hormone signaling pathway: PFKP
hsa04962__22	0.000695119803771656	DOWN	-3.39289303045549	0.00178921933053006	Vasopressin-regulated water reabsorption: ARHGDIA
hsa05200__210	0.000695119803771656	DOWN	-3.39289303045549	0.00178921933053006	Pathways in cancer: MMP1
hsa05161__32	0.000702237011174307	DOWN	-3.39010052590367	0.00180506613405817	Hepatitis B: STAT3
hsa04520__4	0.000709421888140753	DOWN	-3.38730802135186	0.00182104334401158	Adherens junction: CTNND1
hsa04014__35	0.000716675021504472	DOWN	-3.38451551680004	0.00183715193097804	Ras signaling pathway: NFKB1
hsa04931__46	0.000723997002604274	DOWN	-3.38172301224823	0.00185339287178942	Insulin resistance: PIK3R5*
hsa05205__91	0.000731388427313185	UP	3.37893050769641	0.00186976714955303	Proteoglycans in cancer: RAC1*
hsa04670__18	0.000753983516076374	DOWN	-3.37055299404097	0.00191969993042339	Leukocyte transendothelial migration: CDH5
hsa04360__111	0.000753985390448356	UP	3.37055299404097	0.00191969993042339	Axon guidance: RHOA***
hsa05161__195	0.000753985390448356	DOWN	-3.37055299404097	0.00191969993042339	Hepatitis B: IL6
hsa04068__68	0.00076166064002664	DOWN	-3.36776048948915	0.00193400046298656	FoxO signaling pathway: ATG12
hsa04650__35	0.00076166064002664	UP	3.36776048948915	0.00193400046298656	Natural killer cell mediated cytotoxicity: BID
hsa04726__39	0.0007694083816126	DOWN	-3.36496798493734	0.0019510369082997	Serotonergic synapse: CACNA1C
hsa05152__90	0.0007851238403168	DOWN	-3.35938297583371	0.00198820444198823	Tuberculosis: CR1
hsa04380__51	0.000793092819069874	DOWN	-3.35659047128189	0.00200568157070295	Osteoclast differentiation: FOS*
hsa04920__16	0.000801136813160307	DOWN	-3.35379796673008	0.00202330117194653	Adipocytokine signaling pathway: POMC
hsa04015__82	0.00083407587264669	DOWN	-3.34262794852282	0.00210084258003101	Rap1 signaling pathway: ITGA2B
hsa04933__61	0.00083407587264669	DOWN	-3.34262794852282	0.00210084258003101	AGE-RAGE signaling pathway in diabetic complications: MMP2
hsa04340__31	0.000851012440387259	DOWN	-3.33704293941918	0.00213777055546478	Hedgehog signaling pathway: GLI1***
hsa04972__51	0.000851012440387259	DOWN	-3.33704293941918	0.00213777055546478	Pancreatic secretion: CLCA1
hsa04010__134	0.000868267486425686	UP	3.33145793031555	0.00217240293874016	MAPK signaling pathway: ATF4*
hsa04115__55	0.000868267486425686	UP	3.33145793031555	0.00217240293874016	p53 signaling pathway: SHISA5
hsa05134__71	0.000868267486425686	UP	3.33145793031555	0.00217240293874016	Legionellosis: CXCL8
hsa04620__19	0.000877016135746942	UP	3.32866542576374	0.00219137409450599	Toll-like receptor signaling pathway: CXCL10
hsa04151__25	0.00089475912546132	DOWN	-3.32308041666011	0.00223273890669564	PI3K-Akt signaling pathway: CDKN1B
hsa04922__24	0.000903405401968173	UP	3.32028791210829	0.0022513246025175	Glucagon signaling pathway: PFKL
hsa04014__104	0.000921998307879606	UP	3.31470290300466	0.00229158045040447	Ras signaling pathway: BRAP*
hsa05162__105	0.000921998307879606	UP	3.31470290300466	0.00229158045040447	Measles: GSK3B
hsa04740__16	0.000969110301226265	DOWN	-3.30074038024559	0.0024054930726607	Olfactory transduction: PRKG1
hsa05169__93	0.000988571769215675	UP	3.29515537114196	0.00245056247276551	Epstein-Barr virus infection: PLCG1
hsa04071__48	0.00100839216096607	DOWN	-3.28957036203833	0.00249312285686923	Sphingolipid signaling pathway: SMPD1
hsa04151__101	0.0010083945562643	DOWN	-3.28957036203833	0.00249312285686923	PI3K-Akt signaling pathway: PKN3
hsa04261__15 16	0.00102858474078733	DOWN	-3.2839853529347	0.00253636578469737	Adrenergic signaling in cardiomyocytes: ACTC1 TPM1
hsa05221__41	0.00102858474078733	DOWN	-3.2839853529347	0.00253636578469737	Acute myeloid leukemia: MAPK1
hsa04540__21	0.00103881830313705	DOWN	-3.28119284838288	0.00255489777337166	Gap junction: C03758
hsa05132__48	0.00103881953105692	DOWN	-3.28119284838288	0.00255489777337166	Salmonella infection: KLC3
hsa05110__50	0.00104914601441108	DOWN	-3.27840034383107	0.00257356398704188	Vibrio cholerae infection: ACTB
hsa05010__37	0.00104914849072596	DOWN	-3.27840034383107	0.00257356398704188	Alzheimer's disease: MAPT
hsa04610__45	0.00108070826639033	DOWN	-3.27002283017562	0.00264752390162637	Complement and coagulation cascades: C4A
hsa05200__199	0.0011022335118514	DOWN	-3.26443782107199	0.00269323376953028	Pathways in cancer: BCL2L1**
hsa05220__3	0.0011022335118514	DOWN	-3.26443782107199	0.00269323376953028	Chronic myeloid leukemia: BCL2L1
hsa05169__79	0.00114647820849867	DOWN	-3.25326780286473	0.00279770461528442	Epstein-Barr virus infection: ATF2
hsa05014__2	0.00119235955321518	DOWN	-3.24209778465747	0.00290589312644789	Amyotrophic lateral sclerosis (ALS): SLC1A2
hsa04650__16	0.00120409198018365	DOWN	-3.23930528010565	0.00292689370086038	Natural killer cell mediated cytotoxicity: PRKCA
hsa05210__22	0.00120409198018365	DOWN	-3.23930528010565	0.00292689370086038	Colorectal cancer: MYC
hsa04213__53	0.00123993215106343	DOWN	-3.23092776645021	0.00301011952435165	Longevity regulating pathway - multiple species: SOD1
hsa05221__27	0.00126437016585347	DOWN	-3.22534275734658	0.00306548586017892	Acute myeloid leukemia: PIM2
hsa05133__24	0.00128925219014791	DOWN	-3.21975774824295	0.00311776687939243	Pertussis: NFKB1
hsa05221__6	0.00128925219014791	UP	3.21975774824295	0.00311776687939243	Acute myeloid leukemia: CEBPA
hsa04950__22	0.00130186197586052	UP	3.21696524369113	0.00314421420648062	Maturity onset diabetes of the young: NR5A2
hsa04340__40	0.00134037747844964	DOWN	-3.20858773003568	0.00323307995122834	Hedgehog signaling pathway: SUFU
hsa04012__57	0.00137994184814857	DOWN	-3.20021021638024	0.0033242445290656	ErbB signaling pathway: ABL1
hsa04310__32	0.00139336748119052	UP	3.19741771182842	0.00335228872875414	Wnt signaling pathway: PPARD
hsa04068__44	0.00143437042905847	DOWN	-3.18904019817298	0.00344652434296787	FoxO signaling pathway: CDKN1B
hsa04210__31 32 33	0.00146232057777641	UP	3.18345518906935	0.00350919586927442	Apoptosis: TRAF2 RIPK1 TRADD
hsa04340__20 22	0.0015051880049415	DOWN	-3.1750776754139	0.00360745951694526	Hedgehog signaling pathway: GLI1 SUFU*
hsa05231__60	0.00153440625423377	DOWN	-3.16949266631027	0.00367280172191752	Choline metabolism in cancer: PRKCA
hsa04360__11	0.00156414608620651	DOWN	-3.16390765720664	0.00373447331128595	Axon guidance: NFATC2
hsa05034__61	0.00156414608620651	DOWN	-3.16390765720664	0.00373447331128595	Alcoholism: CRH
hsa04210__71	0.00157921420578964	DOWN	-3.16111515265483	0.00376566433081057	Apoptosis: GADD45G
hsa04919__29	0.00159441586757266	DOWN	-3.15832264810301	0.00379709431580359	Thyroid hormone signaling pathway: HIF1A
hsa05205__150	0.00162522408078124	DOWN	-3.15273763899938	0.00386067768367629	Proteoglycans in cancer: PRKCA
hsa05217__22	0.00162522408078124	DOWN	-3.15273763899938	0.00386067768367629	Basal cell carcinoma: LEF1
hsa05164__24	0.0016408327820482	UP	3.14994513444757	0.00388792534359214	Influenza A: IRF7
hsa05211__31	0.0016408327820482	DOWN	-3.14994513444757	0.00388792534359214	Renal cell carcinoma: SOS1
hsa04390__5	0.0016565793252771	DOWN	-3.14715262989575	0.0039202928868963	Hippo signaling pathway: SAV1
hsa04110__46	0.00167246480388705	UP	3.14436012534394	0.00394794141520575	Cell cycle: RB1
hsa04750__39	0.00167246480388705	DOWN	-3.14436012534394	0.00394794141520575	Inflammatory mediator regulation of TRP channels: C01245*
hsa03320__39	0.0016884903187683	UP	3.14156762079212	0.00397578108892937	PPAR signaling pathway: MMP1
hsa05169__83	0.0016884903187683	UP	3.14156762079212	0.00397578108892937	Epstein-Barr virus infection: GSK3B
hsa04066__11	0.00172096589850117	DOWN	-3.13598261168849	0.00404717762613729	HIF-1 signaling pathway: SLC2A1
hsa04922__70	0.00178764677107117	DOWN	-3.12481259348123	0.00419873535355341	Glucagon signaling pathway: PFKFB1
hsa04071__89	0.00180468400078234	DOWN	-3.12202008892941	0.00422818109410225	Sphingolipid signaling pathway: C00533
hsa04668__141	0.00180468400078234	DOWN	-3.12202008892941	0.00422818109410225	TNF signaling pathway: JUN*
hsa04630__33	0.00187433583029061	DOWN	-3.11085007072215	0.00438589915954677	Jak-STAT signaling pathway: RAF1
hsa04152__94	0.00191008006442525	DOWN	-3.10526506161852	0.00446398064807842	AMPK signaling pathway: MLYCD
hsa04740__13	0.001946449329929	DOWN	-3.09968005251489	0.00454332706948646	Olfactory transduction: CNGA3
hsa04730__20	0.00196487139909773	DOWN	-3.09688754796308	0.0045806369217179	Long-term depression: C00025
hsa04211__62	0.00198345340197675	DOWN	-3.09409504341126	0.00461822669431762	Longevity regulating pathway - mammal: EHMT2
hsa04933__43	0.00200219658089113	UP	3.09130253885945	0.00465609823699805	AGE-RAGE signaling pathway in diabetic complications: CASP3
hsa04710__23	0.00204017147742335	UP	3.08571752975582	0.00473854413606732	Circadian rhythm: BHLHE41
hsa04015__96	0.00205940572111511	DOWN	-3.082925025204	0.00477731277774728	Rap1 signaling pathway: PLCE1
hsa04068__96	0.00207880619307469	DOWN	-3.08013252065219	0.00481637094548377	FoxO signaling pathway: CCNG2
hsa04510__23 4 5	0.00211811096627103	DOWN	-3.07454751154855	0.00488335031364817	Focal adhesion: TLN1 ITGB1 ITGA11
hsa04662__10	0.00211811096627103	UP	3.07454751154855	0.00488335031364817	B cell receptor signaling pathway: GSK3B
hsa05200__53	0.00211811096627103	UP	3.07454751154855	0.00488335031364817	Pathways in cancer: BCL2L1
hsa05321__152	0.00211811096627103	UP	3.07454751154855	0.00488335031364817	Inflammatory bowel disease (IBD): FOXP3*
hsa04810__30	0.00221937281622228	DOWN	-3.06058498878948	0.00511054108049223	Regulation of actin cytoskeleton: VCL*
hsa04024__110	0.00224015005469021	DOWN	-3.05779248423766	0.00513948956381306	cAMP signaling pathway: FOS
hsa04380__38	0.00224015005469021	UP	3.05779248423766	0.00513948956381306	Osteoclast differentiation: FOS
hsa04973__36	0.00224015005469021	DOWN	-3.05779248423766	0.00513948956381306	Carbohydrate digestion and absorption: SLC2A2
hsa04650__116	0.00226110538570971	UP	3.05499997968585	0.00517492937850005	Natural killer cell mediated cytotoxicity: FCGR3A
hsa05145__35	0.00226110538570971	UP	3.05499997968585	0.00517492937850005	Toxoplasmosis: CASP3
hsa05020__24	0.00233965946354538	DOWN	-3.04382996147859	0.00532875167515367	Prion diseases: PRNP*
hsa05020__26	0.00233965946354538	DOWN	-3.04382996147859	0.00532875167515367	Prion diseases: PRNP**
hsa05020__25 8	0.00233965946354538	DOWN	-3.04382996147859	0.00532875167515367	Prion diseases: PRNP PRNP*
hsa05020__10 34	0.00233965946354538	DOWN	-3.04382996147859	0.00532875167515367	Prion diseases: PRNP PRNP***
hsa05214__52	0.00236860139971304	UP	3.04103745692677	0.00538813805092108	Glioma: E2F1*
hsa05221__29	0.00245794515315135	DOWN	-3.02986743871951	0.00558461782680941	Acute myeloid leukemia: RPS6KB1
hsa04390__95	0.00252696518725325	DOWN	-3.02148992506407	0.00572758454384663	Hippo signaling pathway: AFP
hsa04668__36	0.00252696518725325	UP	3.02148992506407	0.00572758454384663	TNF signaling pathway: CREB3
hsa04660__44	0.00255036290267225	DOWN	-3.01869742051225	0.00577365288448333	T cell receptor signaling pathway: PAK4
hsa04115__19	0.00257395859596308	UP	3.01590491596043	0.0058200580045904	p53 signaling pathway: RFWD2
hsa04066__37	0.00259775375674223	DOWN	-3.01311241140862	0.00586680205398876	HIF-1 signaling pathway: PDHA1
hsa05100__33	0.00264594848661875	UP	3.00752740230499	0.00596847203644253	Bacterial invasion of epithelial cells: DNM1
hsa04115__1	0.00267035108247081	UP	3.00473489775317	0.00600908944187144	p53 signaling pathway: SIAH1
hsa04930__8	0.00267035108247081	UP	3.00473489775317	0.00600908944187144	Type II diabetes mellitus: C00022
hsa05160__37	0.00271971997292824	DOWN	-2.99914988864954	0.00610560898143794	Hepatitis C: STAT3
hsa05205__77	0.00271974173361552	DOWN	-2.99914988864954	0.00610560898143794	Proteoglycans in cancer: MIR21
hsa05210__40	0.00277003209934184	DOWN	-2.99356487954591	0.00620368333094556	Colorectal cancer: CASP9
hsa05223__22	0.00277003209934184	UP	2.99356487954591	0.00620368333094556	Non-small cell lung cancer: BAD*
hsa04370__28	0.00279547777186598	DOWN	-2.9907723749941	0.00625321753968593	VEGF signaling pathway: SHC2
hsa04530__20 31	0.00282113674990015	DOWN	-2.98797987044228	0.00630311052682804	Tight junction: ACTB MLLT4
hsa04612__39	0.00284701061977061	UP	2.98518736589047	0.00635336455409617	Antigen processing and presentation: PSME3
hsa04150__56	0.00295268709229175	DOWN	-2.97401734768321	0.00658137490678079	mTOR signaling pathway: EIF4B
hsa04610__58	0.00300685665746978	UP	2.96843233857958	0.00669417495187881	Complement and coagulation cascades: F2RL2
hsa04622__5 33	0.00303428002634293	UP	2.96563983402776	0.00674723333668445	RIG-I-like receptor signaling pathway: MAVS TMEM173
hsa03320__55	0.00308981227152298	UP	2.96005482492413	0.00686259723190506	PPAR signaling pathway: SCD
hsa04621__21 31 41	0.00314626975998743	DOWN	-2.9544698158205	0.00696329903299928	NOD-like receptor signaling pathway: NLRP3 CARD8 CASP1
hsa04742__4	0.00314626975998743	UP	2.9544698158205	0.00696329903299928	Taste transduction: TRPM5
hsa05166__5	0.00314626975998743	DOWN	-2.9544698158205	0.00696329903299928	HTLV-I infection: SLC2A1
hsa04932__55	0.00323272067532978	UP	2.94609230216505	0.00714621429287608	Non-alcoholic fatty liver disease (NAFLD): CASP3
hsa04380__72	0.00329155125032012	DOWN	-2.94050729306142	0.00725918403679754	Osteoclast differentiation: MAPK1
hsa04668__116	0.00329155125032012	UP	2.94050729306142	0.00725918403679754	TNF signaling pathway: PGAM5
hsa05200__190	0.00332133077893427	DOWN	-2.93771478850961	0.00731627260682004	Pathways in cancer: MYC*
hsa04211__52	0.00335135549393153	UP	2.93492228395779	0.00737376694742078	Longevity regulating pathway - mammal: PPARG
hsa04012__3	0.00338162717796444	UP	2.93212977940598	0.00743166955250898	ErbB signaling pathway: ELK1
hsa04014__24	0.00341214762448118	DOWN	-2.92933727485416	0.00748124315799316	Ras signaling pathway: PLD1
hsa04728__24	0.00341214762448118	DOWN	-2.92933727485416	0.00748124315799316	Dopaminergic synapse: SLC6A3
hsa04728__60	0.00344291863777227	UP	2.92654477030235	0.00753113401673351	Dopaminergic synapse: CACNA1A
hsa05205__81	0.00344291863777227	UP	2.92654477030235	0.00753113401673351	Proteoglycans in cancer: CTTN
hsa05166__74	0.00350521963633093	DOWN	-2.92095976119872	0.00765849732170443	HTLV-I infection: NFKB1
hsa04623__25	0.00353675328481118	DOWN	-2.9181672566469	0.00771841977022091	Cytosolic DNA-sensing pathway: NFKB1*
hsa04210__86	0.00356854482658469	DOWN	-2.91537475209509	0.00777876534704482	Apoptosis: BCL2L11
hsa04210__24	0.00360059612085429	UP	2.91258224754327	0.00783953662929921	Apoptosis: CASP10
hsa04742__31	0.00376481473297539	DOWN	-2.8986197247842	0.00818760055932958	Taste transduction: C00076*
hsa04360__131	0.00383238677131137	DOWN	-2.89303471568057	0.00832491877837464	Axon guidance: RAC1****
hsa04390__52	0.00386658436146063	DOWN	-2.89024221112875	0.00838950579120615	Hippo signaling pathway: ITGB2
hsa04630__1	0.00393581248877007	UP	2.88465720202512	0.00851023206720249	Jak-STAT signaling pathway: MYC
hsa05010__12	0.00393581248877007	UP	2.88465720202512	0.00851023206720249	Alzheimer's disease: CASP3
hsa05200__203	0.00393581248877007	UP	2.88465720202512	0.00851023206720249	Pathways in cancer: TGFA*
hsa04115__9	0.00400616442041648	DOWN	-2.87907219292149	0.00865239419076158	p53 signaling pathway: RPRM
hsa05211__45	0.00404176680963851	DOWN	-2.87627968836967	0.00871926502331891	Renal cell carcinoma: ETS1
hsa05014__54	0.00407765616948467	DOWN	-2.87348718381786	0.0087866008514469	Amyotrophic lateral sclerosis (ALS): PPP3CA
hsa04014__42	0.0041138345309393	DOWN	-2.87069467926604	0.00884427355106974	Ras signaling pathway: PLA2G4B
hsa04620__77	0.0041138345309393	UP	2.87069467926604	0.00884427355106974	Toll-like receptor signaling pathway: CXCL9
hsa04660__56	0.004150303936816	DOWN	-2.86790217471423	0.00890230718867267	T cell receptor signaling pathway: CD3E
hsa05168__39 40	0.004150303936816	UP	2.86790217471423	0.00890230718867267	Herpes simplex infection: POU2F3 HCFC2
hsa04115__36	0.00422412411251916	UP	2.8623171656106	0.00905031836650342	p53 signaling pathway: EI24
hsa05162__58	0.00429913327748148	DOWN	-2.85673215650697	0.00919006988440011	Measles: STAT3
hsa05200__226	0.00429913327748148	DOWN	-2.85673215650697	0.00919006988440011	Pathways in cancer: CDKN1A*
hsa03320__21	0.00445278586169706	DOWN	-2.84556213829971	0.00950770981150997	PPAR signaling pathway: ACAA1
hsa05032__30	0.00449194414881545	UP	2.84276963374789	0.00956962465022047	Morphine addiction: ADORA1
hsa04727__35	0.00449196856918279	DOWN	-2.84276963374789	0.00956962465022047	GABAergic synapse: PRKACA
hsa05200__75	0.00453146341022473	DOWN	-2.83997712919608	0.00964283097147483	Pathways in cancer: MAPK8
hsa05160__54	0.00461139820958382	UP	2.83439212009245	0.00980182945227149	Hepatitis C: IRF1
hsa04152__53	0.00465184255724155	UP	2.83159961554063	0.0098766239153185	AMPK signaling pathway: G6PC
hsa03320__25	0.00473369621547241	DOWN	-2.826014606437	0.010027751058481	PPAR signaling pathway: EHHADH
hsa05222__36	0.00473369621547241	DOWN	-2.826014606437	0.010027751058481	Small cell lung cancer: PTGS2
hsa04022__60	0.00481685139336125	DOWN	-2.82042959733337	0.0101924141532948	cGMP-PKG signaling pathway: TRPC6*
hsa05134__59	0.00485892268796106	UP	2.81763709278155	0.0102698714630808	Legionellosis: HSPA1A
hsa05161__125	0.00498713875134351	DOWN	-2.80925957912611	0.0105290266446904	Hepatitis B: CDKN1A
hsa04210__69	0.00503055250616257	DOWN	-2.80646707457429	0.0105968701334972	Apoptosis: PTPN13
hsa04920__26	0.00503055250616257	DOWN	-2.80646707457429	0.0105968701334972	Adipocytokine signaling pathway: NPY
hsa05205__324	0.00534414006555331	DOWN	-2.78691954271159	0.0112448367112818	Proteoglycans in cancer: KDR*
hsa05020__59	0.00543692306616982	DOWN	-2.78133453360796	0.011427268950037	Prion diseases: CCL5
hsa04015__30	0.0054838577574542	DOWN	-2.77854202905614	0.0115001883105541	Rap1 signaling pathway: ITGAL
hsa05031__101	0.0054838577574542	DOWN	-2.77854202905614	0.0115001883105541	Amphetamine addiction: FOS*
hsa04950__15	0.00553115785110537	UP	2.77574952450433	0.0115735474412327	Maturity onset diabetes of the young: IAPP
hsa05164__23	0.00553115785110537	UP	2.77574952450433	0.0115735474412327	Influenza A: IRF3
hsa05220__21	0.00562686415122446	DOWN	-2.7701645154007	0.0117607093883768	Chronic myeloid leukemia: NFKBIA
hsa04910__12	0.005675275344283	UP	2.76737201084888	0.0118487137465642	Insulin signaling pathway: FASN
hsa04727__13	0.00577322638455818	UP	2.76178700174525	0.012039836156032	GABAergic synapse: CACNA1A
hsa04611__7	0.00587269921362797	DOWN	-2.75620199264162	0.0122201570569291	Platelet activation: ITPR1
hsa05120__50	0.00587269921362797	DOWN	-2.75620199264162	0.0122201570569291	Epithelial cell signaling in Helicobacter pylori infection: EGFR
hsa04724__13	0.00597369394292988	UP	2.75061698353799	0.0124165607508465	Glutamatergic synapse: GRM5
hsa04350__44 45	0.00602480669759151	UP	2.74782447898617	0.0125089632980933	TGF-beta signaling pathway: TGFBR2 TGFBR1
hsa04360__40 142	0.006076292426536	DOWN	-2.74503197443436	0.0125880413114235	Axon guidance: UNC5D PTPN11
hsa04621__29	0.006076292426536	UP	2.74503197443436	0.0125880413114235	NOD-like receptor signaling pathway: CASP5
hsa04670__73	0.00612817413404954	DOWN	-2.74223946988254	0.0126815409668272	Leukocyte transendothelial migration: MYL12B*
hsa04151__96	0.00618045445792981	DOWN	-2.73944696533073	0.0127756588849836	PI3K-Akt signaling pathway: BCL2
hsa04916__7	0.00623313605000041	DOWN	-2.73665446077891	0.0128562707332061	Melanogenesis: TYRP1
hsa04918__10	0.00623313605000041	DOWN	-2.73665446077891	0.0128562707332061	Thyroid hormone synthesis: TG
hsa04115__54	0.00628622157615628	UP	2.7338619562271	0.0129515464271904	p53 signaling pathway: PERP
hsa04015__17	0.00633971371640911	DOWN	-2.73106945167528	0.0130474502443951	Rap1 signaling pathway: ACTB
hsa05215__8	0.00644792863010715	DOWN	-2.72548444257165	0.0132556432122225	Prostate cancer: NFKBIA
hsa05120__53	0.00655780251523882	DOWN	-2.71989943346802	0.0134374164952385	Epithelial cell signaling in Helicobacter pylori infection: GIT1
hsa05164__70	0.00655780251523882	UP	2.71989943346802	0.0134374164952385	Influenza A: RNASEL
hsa05168__83	0.00655780251523882	UP	2.71989943346802	0.0134374164952385	Herpes simplex infection: RNASEL
hsa04917__57	0.0066133684233977	DOWN	-2.71710692891621	0.0135365133633598	Prolactin signaling pathway: ESR1
hsa04921__53	0.00666935732470115	DOWN	-2.71431442436439	0.0136362594266741	Oxytocin signaling pathway: RGS2
hsa05210__53	0.0067257719992391	DOWN	-2.71152191981258	0.013736658246272	Colorectal cancer: CCND1*
hsa05200__187	0.00683988986080157	DOWN	-2.70593691070895	0.013954563570517	Pathways in cancer: WNT16*
hsa04062__33	0.00695574453911918	DOWN	-2.70035190160532	0.0141448528019534	Chemokine signaling pathway: WAS
hsa04210__107	0.00695574453911918	DOWN	-2.70035190160532	0.0141448528019534	Apoptosis: MCL1
hsa04915__28	0.00695574453911918	DOWN	-2.70035190160532	0.0141448528019534	Estrogen signaling pathway: KCNJ3
hsa03320__40	0.00713283295020925	DOWN	-2.69197438794987	0.014489289852371	PPAR signaling pathway: FABP4
hsa04530__8	0.00719275564025263	UP	2.68918188339805	0.0145952352570569	Tight junction: LLGL2
hsa03320__29	0.00731395829944665	UP	2.68359687429442	0.0148091892722632	PPAR signaling pathway: OLR1
hsa05130__9	0.00731395829944665	DOWN	-2.68359687429442	0.0148091892722632	Pathogenic Escherichia coli infection: TLR4
hsa04976__34	0.00737524413717472	UP	2.68080436974261	0.0149011653051089	Bile secretion: SLCO1B1
hsa05161__45	0.00737524413717472	UP	2.68080436974261	0.0149011653051089	Hepatitis B: PCNA
hsa05161__194	0.00749919961245171	UP	2.67521936063898	0.0151353341265271	Hepatitis B: TNF*
hsa04261__37	0.00756187520845075	DOWN	-2.67242685608716	0.0152291141657867	Adrenergic signaling in cardiomyocytes: CREB3
hsa05142__64	0.00756187520845075	UP	2.67242685608716	0.0152291141657867	Chagas disease (American trypanosomiasis): CASP8
hsa04064__51	0.00762502004077141	DOWN	-2.66963435153535	0.0153234359963738	NF-kappa B signaling pathway: TNFAIP3
hsa04370__14	0.00762502004077141	DOWN	-2.66963435153535	0.0153234359963738	VEGF signaling pathway: PTGS2
hsa04950__13	0.00768863712637441	UP	2.66684184698353	0.0154347747440785	Maturity onset diabetes of the young: INS
hsa04261__73	0.00781730020116587	DOWN	-2.6612568378799	0.0156763149178129	Adrenergic signaling in cardiomyocytes: KCNE1
hsa04917__46	0.00788235230029776	DOWN	-2.65846433332809	0.0157899146825794	Prolactin signaling pathway: GCK
hsa04668__20	0.00794788887268277	UP	2.65567182877627	0.0158873225444372	TNF signaling pathway: IKBKG
hsa05200__212	0.00794788887268277	DOWN	-2.65567182877627	0.0158873225444372	Pathways in cancer: CCND1***
hsa04917__48	0.00801391301155537	DOWN	-2.65287932422446	0.0159852893298435	Prolactin signaling pathway: CCND2
hsa04950__31	0.00801391301155537	UP	2.65287932422446	0.0159852893298435	Maturity onset diabetes of the young: NKX6-1*
hsa05152__24 25	0.00808042782553004	DOWN	-2.65008681967264	0.0161008736841685	Tuberculosis: ITGB2 ITGAM
hsa05150__13	0.00835145654535234	DOWN	-2.63891680146538	0.0166232911533019	Staphylococcus aureus infection: C5AR1
hsa04064__132	0.00848999691720552	DOWN	-2.63333179236175	0.0168455165865144	NF-kappa B signaling pathway: VCAM1
hsa04919__18	0.00848999691720552	DOWN	-2.63333179236175	0.0168455165865144	Thyroid hormone signaling pathway: STAT1
hsa05205__45 46	0.00848999691720552	DOWN	-2.63333179236175	0.0168455165865144	Proteoglycans in cancer: PAK1 FLNA
hsa04728__64	0.00863058878275262	UP	2.62774678325812	0.0170883839017831	Dopaminergic synapse: SCN1A
hsa05134__10	0.00863058878275262	DOWN	-2.62774678325812	0.0170883839017831	Legionellosis: NFKB1
hsa04015__100 101 48	0.00870166211833975	DOWN	-2.6249542787063	0.0172109717056425	Rap1 signaling pathway: PRKCI PARD6A PARD3
hsa05211__2	0.00884537991848159	DOWN	-2.61936926960267	0.0174401562086326	Renal cell carcinoma: TGFB1
hsa05214__23	0.00884537991848159	DOWN	-2.61936926960267	0.0174401562086326	Glioma: MAPK1
hsa05214__56	0.00884537991848159	DOWN	-2.61936926960267	0.0174401562086326	Glioma: MAPK1*
hsa04012__65	0.00891803095987075	DOWN	-2.61657676505086	0.0175649687354268	ErbB signaling pathway: MYC
hsa04810__35 81 80	0.00906493388658769	DOWN	-2.61099175594723	0.0178356133747626	Regulation of actin cytoskeleton: MYL12B MYH9 ACTB
hsa04931__87	0.00921399353979705	DOWN	-2.6054067468436	0.0181099308172371	Insulin resistance: C00031*
hsa04066__51	0.00928934054937363	DOWN	-2.60261424229178	0.0182389455509645	HIF-1 signaling pathway: TFRC
hsa04520__34	0.00944046038284036	DOWN	-2.59702923318815	0.0184994033358154	Adherens junction: RHOA
hsa04921__55	0.00944168589624637	DOWN	-2.59702923318815	0.0184994033358154	Oxytocin signaling pathway: PTGS2*
hsa04915__30	0.00951869106667478	DOWN	-2.59423672863634	0.018630854702377	Estrogen signaling pathway: CREB3*
hsa04910__18	0.00959625581750778	DOWN	-2.59144422408452	0.0187631266192478	Insulin signaling pathway: LIPE
hsa04961__5	0.00975307790508723	DOWN	-2.58585921498089	0.0190499307522442	Endocrine and other factor-regulated calcium reabsorption: TRPV5
hsa04970__39	0.00999257970637977	UP	2.57748170132545	0.0194772673418737	Salivary secretion: KCNN4
hsa05032__38	0.00999259484702833	UP	2.57748170132545	0.0194772673418737	Morphine addiction: CACNA1A
hsa04742__18	0.010155169777541	DOWN	-2.57189669222182	0.0197736414632119	Taste transduction: PDE1A
hsa04024__93	0.0102373369996227	UP	2.56910418767	0.019892405607333	cAMP signaling pathway: ORAI1
hsa04380__32	0.0102373369996227	DOWN	-2.56910418767	0.019892405607333	Osteoclast differentiation: AKT3
hsa04210__105	0.0104034488993181	DOWN	-2.56351917856637	0.0201942980184077	Apoptosis: ACTB
hsa05205__422	0.010487377248251	DOWN	-2.56072667401455	0.020336204179013	Proteoglycans in cancer: CD63
hsa04610__46	0.0105719548556772	UP	2.55793416946274	0.0204790754369252	Complement and coagulation cascades: C2
hsa05205__352	0.0107401338094344	DOWN	-2.55234916035911	0.0207673653423337	Proteoglycans in cancer: ITGA5*
hsa04720__4 15	0.0107428840408453	DOWN	-2.55234916035911	0.0207673653423337	Long-term potentiation: CREBBP ATF4
hsa04650__36	0.0110921301235473	UP	2.54117914215185	0.021420465058731	Natural killer cell mediated cytotoxicity: CASP3
hsa05166__89 90	0.0112705067059041	DOWN	-2.53559413304822	0.0217425894254557	HTLV-I infection: CHUK IKBKG
hsa03320__10	0.0113606465712225	DOWN	-2.5328016284964	0.021894005033156	PPAR signaling pathway: PLIN1
hsa05168__92 93	0.0114514258887897	UP	2.53000912394459	0.022023776095226	Herpes simplex infection: IRF9 STAT1
hsa05205__158	0.0114514258887897	DOWN	-2.53000912394459	0.022023776095226	Proteoglycans in cancer: PDCD4
hsa04012__8	0.0116349181911011	DOWN	-2.52442411484096	0.0223537947659293	ErbB signaling pathway: STAT5A
hsa05032__25	0.0117276388736525	DOWN	-2.52163161028914	0.0225089207799725	Morphine addiction: C00575*
hsa04911__56	0.011821014404128	DOWN	-2.51883910573733	0.022664985780976	Insulin secretion: CAMK2A*
hsa05152__23	0.0120097455925209	UP	2.5132540966337	0.0230033761145227	Tuberculosis: PPP3CA
hsa05200__211	0.0121051090851635	DOWN	-2.51046159208188	0.0231624235957457	Pathways in cancer: CXCL8
hsa04390__59	0.0122011430952385	DOWN	-2.50766908753007	0.0232987275162125	Hippo signaling pathway: SERPINE1
hsa05169__60	0.0122011430952385	UP	2.50766908753007	0.0232987275162125	Epstein-Barr virus infection: NFKB1
hsa04066__61	0.0123952385264738	DOWN	-2.50208407842644	0.0236453331890805	HIF-1 signaling pathway: HMOX1
hsa04725__54	0.0128924905040815	DOWN	-2.48812155566736	0.0245689550275549	Cholinergic synapse: CHRM1*
hsa04722__33	0.012994032680584	UP	2.48532905111554	0.0247373732591868	Neurotrophin signaling pathway: BAD
hsa05031__96	0.0133029164012132	DOWN	-2.4769515374601	0.0252741960747013	Amphetamine addiction: PDYN
hsa05152__120	0.0133029164012132	DOWN	-2.4769515374601	0.0252741960747013	Tuberculosis: TGFB1
hsa04725__53	0.0135123615189403	DOWN	-2.47136652835647	0.0256461891859483	Cholinergic synapse: CHRNA7
hsa04152__35	0.0137248496419189	DOWN	-2.46578151925284	0.0260232012887645	AMPK signaling pathway: PFKFB1
hsa04210__58	0.0139402152529893	UP	2.46019651014921	0.026404903689886	Apoptosis: BID*
hsa04210__114	0.014158558747717	DOWN	-2.45461150104558	0.0267645190009661	Apoptosis: HRK
hsa05169__117	0.014158558747717	DOWN	-2.45461150104558	0.0267645190009661	Epstein-Barr virus infection: CDKN1A
hsa03320__9	0.0142688579000181	UP	2.45181899649376	0.0269188594318615	PPAR signaling pathway: PCK1
hsa04933__35	0.0142688579000181	DOWN	-2.45181899649376	0.0269188594318615	AGE-RAGE signaling pathway in diabetic complications: CCND1
hsa04933__30	0.0143799143969348	UP	2.44902649194195	0.0271011626397598	AGE-RAGE signaling pathway in diabetic complications: CXCL8
hsa04662__29	0.0144917325666355	UP	2.44623398739013	0.0272572227154236	B cell receptor signaling pathway: RAC1
hsa04911__31	0.0144917325666355	DOWN	-2.44623398739013	0.0272572227154236	Insulin secretion: CAMK2A
hsa05205__140	0.0146043167550533	DOWN	-2.44344148283832	0.0274415111827451	Proteoglycans in cancer: MAPK1***
hsa03320__31	0.0148318006607128	DOWN	-2.43785647373468	0.0277855966515248	PPAR signaling pathway: CD36
hsa04014__27	0.0148318006607128	DOWN	-2.43785647373468	0.0277855966515248	Ras signaling pathway: ABL1
hsa04726__72	0.0148318006607128	DOWN	-2.43785647373468	0.0277855966515248	Serotonergic synapse: KCNJ3
hsa04390__88	0.0151788813315252	DOWN	-2.42947896007924	0.0283510119502345	Hippo signaling pathway: ID1
hsa05032__13	0.0151788813315252	DOWN	-2.42947896007924	0.0283510119502345	Morphine addiction: PRKACA
hsa05164__90	0.0151788813315252	DOWN	-2.42947896007924	0.0283510119502345	Influenza A: MAPK1
hsa05164__99	0.0154142233959143	UP	2.42389395097561	0.0287334580961537	Influenza A: FDPS
hsa05215__24	0.0154142233959143	DOWN	-2.42389395097561	0.0287334580961537	Prostate cancer: CDKN1A
hsa04932__14	0.0155330943257255	UP	2.42110144642379	0.0289263471140122	Non-alcoholic fatty liver disease (NAFLD): PKLR
hsa04014__66	0.0156527711901744	UP	2.41830894187198	0.0290915500161599	Ras signaling pathway: RAF1*
hsa05231__59	0.0156527711901744	DOWN	-2.41830894187198	0.0290915500161599	Choline metabolism in cancer: PLA2G4B
hsa04022__59	0.0160166827270935	DOWN	-2.40993142821653	0.0297091281778961	cGMP-PKG signaling pathway: NPPB
hsa04726__71	0.0160166827270935	UP	2.40993142821653	0.0297091281778961	Serotonergic synapse: CACNA1A
hsa04068__57	0.0161396287556892	DOWN	-2.40713892366472	0.0299076552583235	FoxO signaling pathway: IL7R
hsa04330__19	0.0162634035216206	UP	2.4043464191129	0.0301073253370691	Notch signaling pathway: DTX2
hsa04066__59	0.0165134577416343	DOWN	-2.39876141000927	0.0305401447800501	HIF-1 signaling pathway: NOS2
hsa04390__79	0.0166397464788708	DOWN	-2.39596890545746	0.0307132452198411	Hippo signaling pathway: SNAI2
hsa04630__7	0.0166397464788708	UP	2.39596890545746	0.0307132452198411	Jak-STAT signaling pathway: BCL2
hsa04728__61	0.0167668825197762	DOWN	-2.39317640090564	0.0308872277006465	Dopaminergic synapse: KCNJ3
hsa05010__50	0.0167668825197762	DOWN	-2.39317640090564	0.0308872277006465	Alzheimer's disease: ERN1
hsa04742__54	0.0168948035257235	DOWN	-2.39038389635383	0.0310317319310366	Taste transduction: P2RX2*
hsa04742__40	0.0168948035257235	DOWN	-2.39038389635383	0.0310317319310366	Taste transduction: P2RX2
hsa04611__92	0.0168948705510646	DOWN	-2.39038389635383	0.0310317319310366	Platelet activation: RHOA*
hsa04072__3	0.017153421422035	DOWN	-2.3847988872502	0.0314145018050719	Phospholipase D signaling pathway: MAPK1
hsa04261__52	0.017153421422035	DOWN	-2.3847988872502	0.0314145018050719	Adrenergic signaling in cardiomyocytes: MAPK14
hsa05032__4	0.017153421422035	DOWN	-2.3847988872502	0.0314145018050719	Morphine addiction: ADCY1
hsa04014__61	0.017283993725564	DOWN	-2.38200638269838	0.0316228083839676	Ras signaling pathway: RAP1A
hsa04660__43	0.0174154369471901	DOWN	-2.37921387814657	0.0318323015795429	T cell receptor signaling pathway: RHOA
hsa04115__2	0.0179500148304092	UP	2.3680438599393	0.0327775295105334	p53 signaling pathway: IGFBP3
hsa04510__6 4 5	0.0180858729293319	DOWN	-2.36525135538749	0.0329935487710822	Focal adhesion: FLNA ITGB1 ITGA11
hsa04020__22	0.0183603287739722	DOWN	-2.35966634628386	0.0334617437112452	Calcium signaling pathway: C00575
hsa04725__18	0.0186384114771636	DOWN	-2.35408133718023	0.0339356348503782	Cholinergic synapse: ITPR1
hsa04623__8	0.0189201722242954	UP	2.3484963280766	0.0344152987506786	Cytosolic DNA-sensing pathway: TBK1
hsa04510__47	0.0192056507579363	DOWN	-2.34291131897297	0.0349007908841029	Focal adhesion: CCND1
hsa04650__14	0.0193497966938019	UP	2.34011881442115	0.0350948532699361	Natural killer cell mediated cytotoxicity: CSF2
hsa05142__67	0.0193497966938019	UP	2.34011881442115	0.0350948532699361	Chagas disease (American trypanosomiasis): IFNGR1*
hsa04810__29	0.0194948871115933	DOWN	-2.33732630986934	0.0353239082764549	Regulation of actin cytoskeleton: ACTN4
hsa04024__118	0.0197879216097742	DOWN	-2.33174130076571	0.0357858563087254	cAMP signaling pathway: MYL9
hsa04724__44	0.0197879216097742	DOWN	-2.33174130076571	0.0357858563087254	Glutamatergic synapse: PRKACA*
hsa05231__38	0.0200847948680163	UP	2.32615629166208	0.0362878168817333	Choline metabolism in cancer: RPS6KB1
hsa03320__7	0.0205373919931554	DOWN	-2.31777877800663	0.0370698939050326	PPAR signaling pathway: AQP7
hsa04932__56	0.0209988577234856	UP	2.30940126435118	0.0378664622480128	Non-alcoholic fatty liver disease (NAFLD): CASP7
hsa05200__218	0.021154674721146	UP	2.30660875979937	0.038110866539821	Pathways in cancer: CSF3R*
hsa04152__63	0.0214693328184359	UP	2.30102375069574	0.0386037094409962	AMPK signaling pathway: PPARG
hsa04152__38	0.0214693328184359	UP	2.30102375069574	0.0386037094409962	AMPK signaling pathway: PFKL
hsa04510__26 4 5	0.0216281711436614	DOWN	-2.29823124614392	0.0388521353527149	Focal adhesion: ACTN4 ITGB1 ITGA11
hsa04014__100	0.0217880582611524	DOWN	-2.29543874159211	0.0391019689328609	Ras signaling pathway: REL
hsa04610__7	0.0219489595086372	DOWN	-2.29264623704029	0.0393531440045127	Complement and coagulation cascades: C00290
hsa04024__31	0.0221108935546554	DOWN	-2.28985373248848	0.0395679704659024	cAMP signaling pathway: C00165
hsa04024__32	0.0221108935546554	DOWN	-2.28985373248848	0.0395679704659024	cAMP signaling pathway: C01245
hsa04015__14	0.0222738657576955	DOWN	-2.28706122793666	0.0397083432245824	Rap1 signaling pathway: MAPK14
hsa04071__1	0.0222738657576955	UP	2.28706122793666	0.0397083432245824	Sphingolipid signaling pathway: MAPK1
hsa04919__99	0.0222738657576955	DOWN	-2.28706122793666	0.0397083432245824	Thyroid hormone signaling pathway: WNT4
hsa04950__1	0.0222738657576955	UP	2.28706122793666	0.0397083432245824	Maturity onset diabetes of the young: HNF1B
hsa05166__33	0.0227103539931047	DOWN	-2.25355117331488	0.0404481091498046	HTLV-I infection: HLA-A
hsa04151__97	0.0227690651654226	UP	2.27868371428122	0.0404759446034334	PI3K-Akt signaling pathway: MCL1
hsa05032__37	0.0227690651654226	DOWN	-2.27868371428122	0.0404759446034334	Morphine addiction: KCNJ3
hsa04012__24	0.0232738026292951	DOWN	-2.27030620062577	0.0413340974862434	ErbB signaling pathway: CDKN1A
hsa04068__46	0.0243124836183385	DOWN	-2.25355117331488	0.0431380138988272	FoxO signaling pathway: PLK4
hsa04976__37	0.024846697362161	DOWN	-2.24517365965943	0.0440028270851996	Bile secretion: ABCB11
hsa04152__77	0.024846726736241	UP	2.24517365965943	0.0440028270851996	AMPK signaling pathway: CCND1
hsa04210__85	0.0250270529473793	DOWN	-2.24238115510762	0.0442804449040732	Apoptosis: FASLG*
hsa04024__115	0.0257597348242308	DOWN	-2.23121113690036	0.0454911106529415	cAMP signaling pathway: F2R
hsa04670__2	0.0257597348242308	DOWN	-2.23121113690036	0.0454911106529415	Leukocyte transendothelial migration: MMP2
hsa04750__51	0.0259457175622785	UP	2.22841863234854	0.0457335865849169	Inflammatory mediator regulation of TRP channels: TRPV4
hsa04750__61	0.0259457175622785	UP	2.22841863234854	0.0457335865849169	Inflammatory mediator regulation of TRP channels: TRPV4*
hsa04750__7	0.0261329363449983	UP	2.22562612779673	0.0458914702104175	Inflammatory mediator regulation of TRP channels: TRPV1
hsa04750__58	0.0261329363449983	UP	2.22562612779673	0.0458914702104175	Inflammatory mediator regulation of TRP channels: TRPV1**
hsa04152__49	0.0261329819718716	UP	2.22562612779673	0.0458914702104175	AMPK signaling pathway: GYS1
hsa04810__23	0.0261329819718716	DOWN	-2.22562612779673	0.0458914702104175	Regulation of actin cytoskeleton: GSN
hsa03320__27	0.0263213522199003	DOWN	-2.22283362324491	0.0460072751825048	PPAR signaling pathway: CPT1C
hsa05016__48	0.0263213522199003	DOWN	-2.22283362324491	0.0460072751825048	Huntington's disease: HIP1
hsa05016__46	0.0263213522199003	DOWN	-2.22283362324491	0.0460072751825048	Huntington's disease: HTT**
hsa05152__76	0.0263213522199003	UP	2.22283362324491	0.0460072751825048	Tuberculosis: TNF*
hsa05211__21	0.0263213522199003	DOWN	-2.22283362324491	0.0460072751825048	Renal cell carcinoma: TGFB1*
hsa03320__61	0.0276730909088705	DOWN	-2.20328609138221	0.0482801651047054	PPAR signaling pathway: APOA1
hsa04115__3	0.0276730909088705	DOWN	-2.20328609138221	0.0482801651047054	p53 signaling pathway: GADD45G
hsa04022__58	0.0280701322587166	DOWN	-2.19770108227858	0.0488368319575264	cGMP-PKG signaling pathway: MYH7
hsa04622__9 35	0.0280701322587166	UP	2.19770108227858	0.0488368319575264	RIG-I-like receptor signaling pathway: IRF3 PIN1
hsa04810__31	0.0280701322587166	DOWN	-2.19770108227858	0.0488368319575264	Regulation of actin cytoskeleton: MSN
hsa05211__49	0.0282704875438915	UP	2.19490857772676	0.049139913131334	Renal cell carcinoma: TGFA*
hsa04064__113	0.0286748971576802	DOWN	-2.18932356862313	0.0497508141821616	NF-kappa B signaling pathway: CFLAR
hsa05145__9	0.0286748971576802	DOWN	-2.18932356862313	0.0497508141821616	Toxoplasmosis: MAPK1
hsa05169__11	0.0289313660019264	UP	2.08041589110234	0.0501494803668079	Epstein-Barr virus infection: HLA-A
hsa04742__34	0.0292908327326358	UP	2.18094605496769	0.050725783137901	Taste transduction: GRM1
hsa05152__69	0.0294986806612697	UP	2.17815355041587	0.0510386933356591	Tuberculosis: HLA-DMA
hsa04530__6 11 45	0.029707779317725	DOWN	-2.17536104586405	0.0513059902003725	Tight junction: CLDN24 TJP1 TJP2
hsa04971__37	0.029707779317725	DOWN	-2.17536104586405	0.0513059902003725	Gastric acid secretion: KCNQ1
hsa04068__14	0.0299181512317926	DOWN	-2.17256854131224	0.0515745010683838	FoxO signaling pathway: G6PC
hsa04666__27	0.0299181512317926	UP	2.17256854131224	0.0515745010683838	Fc gamma R-mediated phagocytosis: ARPC5
hsa04024__12	0.0307724937749737	UP	2.16139852310498	0.052998639599611	cAMP signaling pathway: SLC9A1
hsa05200__201	0.030989323859394	UP	2.15860601855316	0.0533232046994518	Pathways in cancer: PDGFB
hsa05152__20	0.0312073954159423	UP	2.15581351400135	0.0536003884772021	Tuberculosis: FCGR1A
hsa04666__51	0.0312074640734748	DOWN	-2.15581351400135	0.0536003884772021	Fc gamma R-mediated phagocytosis: NCF1
hsa04062__43	0.0314269206219293	DOWN	-2.15302100944953	0.0538297026878808	Chemokine signaling pathway: STAT1
hsa04621__6	0.0314269206219293	DOWN	-2.15302100944953	0.0538297026878808	NOD-like receptor signaling pathway: NFKB1
hsa05168__9	0.0314269206219293	DOWN	-2.15302100944953	0.0538297026878808	Herpes simplex infection: NFKB1
hsa05162__28 34	0.0316476997263206	UP	2.15022850489772	0.0541584952511443	Measles: IRF9 STAT1
hsa03320__60	0.0323180348425558	DOWN	-2.14185099124227	0.055255311618892	PPAR signaling pathway: CYP27A1
hsa04010__87	0.0325441667217513	UP	2.13905848669046	0.0555913538819733	MAPK signaling pathway: STK3
hsa04727__8	0.032771652515865	DOWN	-2.13626598213864	0.055929096346331	GABAergic synapse: ADCY1
hsa05211__22	0.033230711152178	UP	2.13068097303501	0.0566610764563907	Renal cell carcinoma: TGFA
hsa04064__134	0.0336952615230799	DOWN	-2.12509596393138	0.0573490909437202	NF-kappa B signaling pathway: CCL21
hsa04151__37	0.0336952615230799	DOWN	-2.12509596393138	0.0573490909437202	PI3K-Akt signaling pathway: G6PC
hsa03320__45	0.034165354662895	DOWN	-2.11951095482775	0.0579916001911288	PPAR signaling pathway: PDPK1
hsa04062__25	0.034165354662895	DOWN	-2.11951095482775	0.0579916001911288	Chemokine signaling pathway: ROCK1
hsa04064__50	0.034165354662895	DOWN	-2.11951095482775	0.0579916001911288	NF-kappa B signaling pathway: NFKBIA*
hsa05014__31 34	0.0344024957908055	DOWN	-2.11671845027593	0.0582888093696334	Amyotrophic lateral sclerosis (ALS): NEFL PRPH
hsa05162__27 70	0.0344024957908055	UP	2.11671845027593	0.0582888093696334	Measles: STAT1 GNB2L1
hsa04014__67	0.0348809993439805	DOWN	-2.1111334411723	0.0590463042949003	Ras signaling pathway: RAPGEF5*
hsa04010__12	0.0353651743903078	UP	2.10554843206867	0.0598120276142109	MAPK signaling pathway: PLA2G4B
hsa04151__4	0.035609404944819	UP	2.10275592751686	0.0601709279598155	PI3K-Akt signaling pathway: RPS6
hsa04360__40 139	0.0366007662745473	DOWN	-2.0915859093096	0.0617905119765269	Axon guidance: UNC5D DCC
hsa05016__12	0.0368522491649848	DOWN	-2.08879340475778	0.0621592245790004	Huntington's disease: REST
hsa03320__66	0.0371052022456007	UP	2.08600090020597	0.0624177932135038	PPAR signaling pathway: UCP1
hsa04917__56	0.0371052022456007	DOWN	-2.08600090020597	0.0624177932135038	Prolactin signaling pathway: LHCGR
hsa04950__11	0.0371052022456007	UP	2.08600090020597	0.0624177932135038	Maturity onset diabetes of the young: HNF4G
hsa05110__46	0.0373596321271792	DOWN	-2.08320839565415	0.0627895785035508	Vibrio cholerae infection: PLCG1
hsa05200__205	0.0376155454360004	UP	2.08041589110234	0.0631631902361436	Pathways in cancer: SLC2A1
hsa04024__62	0.0383922524197855	UP	2.07203837744689	0.06435240169204	cAMP signaling pathway: BAD
hsa04550__25	0.0383922524197855	UP	2.07203837744689	0.06435240169204	Signaling pathways regulating pluripotency of stem cells: MAPK1
hsa04210__50	0.0386541660079987	DOWN	-2.06924587289508	0.0646760266509613	Apoptosis: SPTA1
hsa05222__44	0.0386541660079987	UP	2.06924587289508	0.0646760266509613	Small cell lung cancer: RB1
hsa05145__8	0.0389175963849846	DOWN	-2.06645336834326	0.0649433069337354	Toxoplasmosis: NFKB1
hsa05161__227	0.0389175963849846	UP	2.06645336834326	0.0649433069337354	Hepatitis B: MYD88*
hsa05168__106 134	0.0389175963849846	UP	2.06645336834326	0.0649433069337354	Herpes simplex infection: SRSF8 C1QBP
hsa04115__58	0.0394490343917294	UP	2.06086835923963	0.065655213128485	p53 signaling pathway: CASP3
hsa04670__28 41 49	0.0394490343917294	DOWN	-2.06086835923963	0.065655213128485	Leukocyte transendothelial migration: ACTB CTNNA1 CTNNB1
hsa05145__10	0.0394490343917294	DOWN	-2.06086835923963	0.065655213128485	Toxoplasmosis: MAPK8
hsa04062__44	0.0397170555022004	UP	2.05807585468782	0.066042785211181	Chemokine signaling pathway: MAPK1
hsa04024__3	0.0399866203627248	DOWN	-2.055283350136	0.0664322366592041	cAMP signaling pathway: RYR2
hsa04668__38	0.0405304084587323	UP	2.04969834103237	0.067276181531765	TNF signaling pathway: CEBPB
hsa04390__80	0.0408046452933711	DOWN	-2.04690583648055	0.0676119298996864	Hippo signaling pathway: BIRC2
hsa04931__35	0.0408046452933711	DOWN	-2.04690583648055	0.0676119298996864	Insulin resistance: C00369
hsa04213__62	0.0413578386432855	DOWN	-2.04132082737692	0.0684079038826879	Longevity regulating pathway - multiple species: CAT*
hsa04724__36	0.0413578386432855	DOWN	-2.04132082737692	0.0684079038826879	Glutamatergic synapse: TRPC1
hsa04210__51	0.041636808844978	DOWN	-2.03852832282511	0.0685675405957176	Apoptosis: LMNA
hsa04727__26	0.041636808844978	UP	2.03852832282511	0.0685675405957176	GABAergic synapse: KCNJ6
hsa05032__81	0.041636808844978	UP	2.03852832282511	0.0685675405957176	Morphine addiction: KCNJ6
hsa05032__91	0.041636808844978	UP	2.03852832282511	0.0685675405957176	Morphine addiction: KCNJ6**
hsa05032__85	0.041636808844978	UP	2.03852832282511	0.0685675405957176	Morphine addiction: KCNJ6*
hsa03320__8	0.0421995306256179	UP	2.03294331372148	0.0692514568083284	PPAR signaling pathway: GK
hsa04066__53	0.0421995306256179	DOWN	-2.03294331372148	0.0692514568083284	HIF-1 signaling pathway: EGF*
hsa04924__58	0.0421995306256179	DOWN	-2.03294331372148	0.0692514568083284	Renin secretion: PPP3CA
hsa05031__59	0.0421995306256179	DOWN	-2.03294331372148	0.0692514568083284	Amphetamine addiction: PPP3CA
hsa04310__57	0.0427686735070948	UP	2.02735830461785	0.0701242037694862	Wnt signaling pathway: SIAH1
hsa04071__66	0.0433442928041123	DOWN	-2.02177329551422	0.0709441865670096	Sphingolipid signaling pathway: C01245
hsa05142__44	0.0433442928041123	DOWN	-2.02177329551422	0.0709441865670096	Chagas disease (American trypanosomiasis): PLCB1
hsa04015__67	0.0436345484553759	DOWN	-2.0189807909624	0.0713571075262414	Rap1 signaling pathway: AKT3
hsa04012__48	0.0439264440544931	DOWN	-2.01618828641059	0.0717096336910447	ErbB signaling pathway: CAMK2A
hsa04666__49	0.0439264440544931	UP	2.01618828641059	0.0717096336910447	Fc gamma R-mediated phagocytosis: ARF6*
hsa05205__120	0.0442199865781123	UP	2.01339578185877	0.0721261760245426	Proteoglycans in cancer: PLAU
hsa04912__20	0.0445151830164878	DOWN	-2.01060327730696	0.0725446911430881	GnRH signaling pathway: PLA2G4B
hsa04014__65	0.0451105656660263	DOWN	-2.00501826820333	0.0733876648367649	Ras signaling pathway: MLLT4*
hsa04152__82	0.0451105656660263	UP	2.00501826820333	0.0733876648367649	AMPK signaling pathway: HMGCR
hsa04915__58	0.0454107659249343	DOWN	-2.00222576365151	0.0738121359627609	Estrogen signaling pathway: CREB3***
hsa04068__41	0.0457126481939095	DOWN	-1.9994332590997	0.0741104969424986	FoxO signaling pathway: CDKN2B
hsa04933__24	0.0457126481939095	DOWN	-1.9994332590997	0.0741104969424986	AGE-RAGE signaling pathway in diabetic complications: THBD
hsa05010__59	0.0457126481939095	DOWN	-1.9994332590997	0.0741104969424986	Alzheimer's disease: LRP1
hsa04210__56	0.0466284576960199	UP	1.99105574544425	0.0755300620782943	Apoptosis: BAX
hsa05145__23	0.0469371387050133	UP	1.98826324089244	0.0759645853804651	Toxoplasmosis: CIITA
hsa04068__42	0.0472475371385883	DOWN	-1.98547073634062	0.0763354447836693	FoxO signaling pathway: CDKN2D
hsa04210__60	0.0472475371385883	UP	1.98547073634062	0.0763354447836693	Apoptosis: BBC3
hsa04668__102	0.0475596601181009	UP	1.9826782317888	0.0767737125102334	TNF signaling pathway: AKT3
hsa03320__64	0.0481891082632396	DOWN	-1.97709322268517	0.0777230338425984	PPAR signaling pathway: APOA5
hsa04014__58 59	0.0485064477341607	DOWN	-1.97430071813336	0.0781007843123289	Ras signaling pathway: STK4 STK4
hsa04015__95	0.0485064477341607	DOWN	-1.97430071813336	0.0781007843123289	Rap1 signaling pathway: THBS1
hsa04360__122	0.0488255403614119	DOWN	-1.97150821358154	0.0785472520026481	Axon guidance: CFL1**
hsa04919__103	0.0494690138303873	DOWN	-1.96592320447791	0.079446390587434	Thyroid hormone signaling pathway: CCND1
hsa04921__65	0.0494690138303873	UP	1.96592320447791	0.079446390587434	Oxytocin signaling pathway: TRPM2
hsa04022__63	0.0504475526810205	DOWN	-1.95754569082247	0.0809487203139518	cGMP-PKG signaling pathway: C00575
hsa04970__28	0.0511087875857797	DOWN	-1.95196068171884	0.0819397712232766	Salivary secretion: AQP5
hsa05169__30	0.0531365663669798	DOWN	-1.93520565440795	0.085118165561428	Epstein-Barr virus infection: FGR
hsa04390__96	0.0534809627967042	DOWN	-1.93241314985613	0.0855240247617082	Hippo signaling pathway: FGF1
hsa05145__4 5	0.0534809627967042	UP	1.93241314985613	0.0855240247617082	Toxoplasmosis: MAP3K7 TAB1
hsa04150__31	0.0538272213555269	DOWN	-1.92962064530432	0.0860045484073427	mTOR signaling pathway: EIF4E
hsa04713__56	0.0548772433955208	DOWN	-1.92124313164887	0.0876077657945484	Circadian entrainment: KCNJ3
hsa04930__9	0.0555866789698742	DOWN	-1.91565812254524	0.0885898358726191	Type II diabetes mellitus: C00238
hsa04620__22	0.0555867038285354	UP	1.91565812254524	0.0885898358726191	Toll-like receptor signaling pathway: CD86
hsa04910__43	0.0563037898946414	DOWN	-1.91007311344161	0.089580712287918	Insulin signaling pathway: G6PC
hsa04919__43	0.0563037898946414	DOWN	-1.91007311344161	0.089580712287918	Thyroid hormone signaling pathway: TBC1D4
hsa05031__8	0.0570284852118753	DOWN	-1.90448810433798	0.090656957456103	Amphetamine addiction: DRD1
hsa04024__2	0.0577610765062733	DOWN	-1.89890309523435	0.0917439245606825	cAMP signaling pathway: CACNA1C
hsa04062__40	0.0581302571100771	DOWN	-1.89611059068253	0.0921744751981728	Chemokine signaling pathway: PRKACA
hsa04921__54	0.0581302571100771	DOWN	-1.89611059068253	0.0921744751981728	Oxytocin signaling pathway: RCAN1
hsa04310__33	0.0588745013262448	UP	1.8905255815789	0.0931972940118062	Wnt signaling pathway: CCND1
hsa04930__26	0.0588745013262448	UP	1.8905255815789	0.0931972940118062	Type II diabetes mellitus: INS*
hsa05200__222	0.0592495799083149	UP	1.88773307702709	0.0937120880873095	Pathways in cancer: CASP9*
hsa05219__21	0.0600056875105362	UP	1.88214806792346	0.0948281638623192	Bladder cancer: RB1
hsa04350__41	0.0607697791170103	DOWN	-1.87656305881983	0.0957939722826026	TGF-beta signaling pathway: SMAD4***
hsa04933__78	0.0607697791170103	DOWN	-1.87656305881983	0.0957939722826026	AGE-RAGE signaling pathway in diabetic complications: TGFB1
hsa05212__10	0.0607697791170103	UP	1.87656305881983	0.0957939722826026	Pancreatic cancer: BCL2L1
hsa04020__18	0.0615418092687339	UP	1.8709780497162	0.0967674139045615	Calcium signaling pathway: C00002
hsa04020__17	0.0615418092687339	UP	1.8709780497162	0.0967674139045615	Calcium signaling pathway: C00004
hsa04020__15	0.0615418092687339	UP	1.8709780497162	0.0967674139045615	Calcium signaling pathway: C13051
hsa05162__27 28	0.0619310183033685	UP	1.86818554516438	0.0972979794247737	Measles: STAT1 IRF9
hsa04670__39	0.0623221553556958	DOWN	-1.86539304061257	0.097830684973561	Leukocyte transendothelial migration: MAPK14
hsa04115__21	0.0627153336689115	UP	1.86260053606075	0.0981199933088133	p53 signaling pathway: DDB2
hsa05200__173	0.0627153336689115	DOWN	-1.86260053606075	0.0981199933088133	Pathways in cancer: CCNA1
hsa05200__215	0.0627153336689115	DOWN	-1.86260053606075	0.0981199933088133	Pathways in cancer: CSF1R
hsa05221__16	0.0627153336689115	DOWN	-1.86260053606075	0.0981199933088133	Acute myeloid leukemia: CCNA1
hsa04740__42	0.0631105608138974	DOWN	-1.85980803150893	0.0986561928197281	Olfactory transduction: PDE2A
hsa04971__39	0.0635078443689497	DOWN	-1.85701552695712	0.0991123252236349	Gastric acid secretion: EZR
hsa05213__27	0.0635078443689497	UP	1.85701552695712	0.0991123252236349	Endometrial cancer: ELK1
hsa04014__76	0.064712109385756	UP	1.84863801330167	0.100907928245507	Ras signaling pathway: RALBP1*
hsa05132__20	0.0655253740369768	UP	1.84305300419804	0.102091358055953	Salmonella infection: ACTB
hsa05200__195	0.0659351555942069	DOWN	-1.84026049964623	0.102644703696367	Pathways in cancer: BIRC8
hsa04151__5	0.0667610553030013	DOWN	-1.8346754905426	0.103758497034193	PI3K-Akt signaling pathway: EIF4B
hsa05160__77	0.0667610553030013	UP	1.8346754905426	0.103758497034193	Hepatitis C: NFKB1*
hsa04668__111	0.0675954547182198	UP	1.82909048143897	0.104881799682523	TNF signaling pathway: BAG4
hsa04912__17	0.0675954547182198	DOWN	-1.82909048143897	0.104881799682523	GnRH signaling pathway: MAPK14
hsa03320__37	0.0697190411886572	DOWN	-1.81512795867989	0.108087523426969	PPAR signaling pathway: HMGCS2
hsa04210__52	0.0705836719541371	DOWN	-1.80954294957626	0.10933777378551	Apoptosis: PARP2
hsa04390__18	0.0714570784204199	UP	1.80395794047263	0.110508518808205	Hippo signaling pathway: MOB1A
hsa04520__7 68	0.0714570784204199	UP	1.80395794047263	0.110508518808205	Adherens junction: CDH1 CTNNB1
hsa04620__29	0.071897091773217	UP	1.80116543592082	0.111097562041015	Toll-like receptor signaling pathway: CXCL8
hsa05150__40	0.072339322138217	UP	1.798372931369	0.111689060228192	Staphylococcus aureus infection: FCGR1A
hsa05164__41 42	0.073230464726931	UP	1.79278792226537	0.112972120871842	Influenza A: STAT1 IRF9
hsa04064__97	0.0736793923714736	DOWN	-1.78999541771355	0.113571434180475	NF-kappa B signaling pathway: PLCG2
hsa04912__46	0.0741305678695541	DOWN	-1.78720291316174	0.114173227071223	GnRH signaling pathway: JUN
hsa04726__41	0.0764203137949845	DOWN	-1.77324039040266	0.11750717644908	Serotonergic synapse: HTR3C
hsa04742__57	0.0764203137949845	DOWN	-1.77324039040266	0.11750717644908	Taste transduction: HTR3C
hsa04062__38	0.0768852582958605	DOWN	-1.77044788585085	0.117932571704426	Chemokine signaling pathway: NCF1
hsa05152__94	0.0768852582958605	UP	1.77044788585085	0.117932571704426	Tuberculosis: CAMP
hsa05231__50	0.0768852582958605	DOWN	-1.77044788585085	0.117932571704426	Choline metabolism in cancer: WASF2
hsa04014__41	0.0787676545921198	DOWN	-1.75927786764359	0.120721389052686	Ras signaling pathway: RAC1*
hsa04062__53	0.0797228193043867	DOWN	-1.75369285853996	0.122085719211852	Chemokine signaling pathway: NFKB1
hsa04012__25	0.0806873776911008	UP	1.74810784943633	0.123462200880764	ErbB signaling pathway: CDKN1B
hsa04976__36	0.0816612986734487	UP	1.7425228403327	0.124850756881538	Bile secretion: SLC10A1
hsa04726__16	0.0821519640421804	DOWN	-1.73973033578088	0.125396864691517	Serotonergic synapse: ITPR1
hsa04726__46	0.0821519640421804	DOWN	-1.73973033578088	0.125396864691517	Serotonergic synapse: ITPR1*
hsa04350__32	0.0826449235068429	UP	1.73693783122907	0.125944696893234	TGF-beta signaling pathway: RPS6KB1
hsa04933__62	0.0826449235068429	UP	1.73693783122907	0.125944696893234	AGE-RAGE signaling pathway in diabetic complications: AGER**
hsa04064__4	0.0831402779006531	DOWN	-1.73414532667725	0.126494398522532	NF-kappa B signaling pathway: BIRC2
hsa04210__106	0.0831402779006531	DOWN	-1.73414532667725	0.126494398522532	Apoptosis: TUBA1B
hsa04115__49	0.0836380349772553	UP	1.73135282212543	0.127148760293093	p53 signaling pathway: MDM2*
hsa03320__32	0.0846407881934584	DOWN	-1.7257678130218	0.128569151993135	PPAR signaling pathway: FABP3
hsa04064__131	0.0851457998398468	DOWN	-1.72297530846999	0.129231791517829	NF-kappa B signaling pathway: CCL4L1
hsa04520__9 57	0.0856532451822365	DOWN	-1.72018280391817	0.129792296530179	Adherens junction: LEF1 CTNNB1
hsa04921__11	0.0856532451822365	UP	1.72018280391817	0.129792296530179	Oxytocin signaling pathway: PRKACA
hsa04068__50	0.0861631319726731	DOWN	-1.71739029936636	0.130459730037593	FoxO signaling pathway: TNFSF10
hsa04919__84	0.0866754679623306	UP	1.71459779481454	0.131129794123365	Thyroid hormone signaling pathway: TP53*
hsa04919__27	0.0882272486213826	DOWN	-1.7062202811591	0.133370072533852	Thyroid hormone signaling pathway: GATA4
hsa05134__68	0.0898013509927921	UP	1.69784276750365	0.135531516879885	Legionellosis: TNF
hsa05162__93	0.0898013509927921	UP	1.69784276750365	0.135531516879885	Measles: TP53
hsa05205__369	0.090331048297385	UP	1.69505026295184	0.136112301323806	Proteoglycans in cancer: HOXD10
hsa05213__29	0.090331048297385	DOWN	-1.69505026295184	0.136112301323806	Endometrial cancer: CCND1
hsa04728__36	0.0908632239115296	UP	1.69225775840002	0.136804485360388	Dopaminergic synapse: TH
hsa05212__54	0.091397984105651	DOWN	-1.68946525384821	0.137499449267028	Pancreatic cancer: C00416
hsa04914__23	0.0919352380762724	DOWN	-1.68667274929639	0.138197049876253	Progesterone-mediated oocyte maturation: PRKACA
hsa04913__12	0.0924750263977083	DOWN	-1.68388024474458	0.138786401438733	Ovarian steroidogenesis: HSD3B1
hsa05215__9	0.0924750263977083	UP	1.68388024474458	0.138786401438733	Prostate cancer: CDKN1B
hsa04064__135	0.0930173567959249	DOWN	-1.68108774019276	0.139377682152746	NF-kappa B signaling pathway: CCL19
hsa05205__34	0.0930173567959249	DOWN	-1.68108774019276	0.139377682152746	Proteoglycans in cancer: SLC9A1
hsa05150__48	0.0935622369935338	DOWN	-1.67829523564095	0.140082424948885	Staphylococcus aureus infection: C3AR1
hsa04612__17 28	0.0946596776594151	DOWN	-1.67271022653732	0.141612686562135	Antigen processing and presentation: CD4 HLA-DMA
hsa04022__23	0.0952122535543583	UP	1.6699177219855	0.14232603375389	cGMP-PKG signaling pathway: CACNA1C
hsa04921__43	0.0957674101016371	UP	1.66712521743368	0.14304210141572	Oxytocin signaling pathway: CACNG3
hsa04022__9	0.0968854959601173	UP	1.66154020833005	0.144597177846752	cGMP-PKG signaling pathway: ITPR1
hsa04151__63	0.0980139968019894	DOWN	-1.65595519922642	0.146165317453125	PI3K-Akt signaling pathway: CASP9
hsa04520__64	0.0985821720599344	UP	1.65316269467461	0.146663421457337	Adherens junction: CTNND1**
hsa05214__27	0.0985821720599344	DOWN	-1.65316269467461	0.146663421457337	Glioma: MTOR
hsa05214__48	0.0985821720599344	DOWN	-1.65316269467461	0.146663421457337	Glioma: MTOR*
hsa04932__7	0.0997264106401282	UP	1.64757768557098	0.148248358855064	Non-alcoholic fatty liver disease (NAFLD): SREBF1
hsa04380__16	0.100302489301673	UP	1.64478518101916	0.148986859603038	Osteoclast differentiation: NFKB1
hsa04660__26	0.100881217760556	DOWN	-1.64199267646735	0.149609951201329	T cell receptor signaling pathway: GRB2
hsa04932__97	0.100881217760556	UP	1.64199267646735	0.149609951201329	Non-alcoholic fatty liver disease (NAFLD): TNF*
hsa04961__20	0.101462429912803	UP	1.63920017191553	0.150116718345292	Endocrine and other factor-regulated calcium reabsorption: CALB1*
hsa04012__37 7	0.101462603671379	DOWN	-1.63920017191553	0.150116718345292	ErbB signaling pathway: ERBB3 ERBB3
hsa04115__56	0.101462603671379	UP	1.63920017191553	0.150116718345292	p53 signaling pathway: SESN3
hsa05215__46	0.102046654682351	DOWN	-1.63640766736372	0.150862048897039	Prostate cancer: MTOR
hsa04072__36	0.102633378435081	DOWN	-1.6336151628119	0.151610155722891	Phospholipase D signaling pathway: MTOR
hsa05133__59	0.103222782564368	DOWN	-1.63082265826009	0.152361043549449	Pertussis: C3
hsa04064__115	0.105007153452991	DOWN	-1.62244514460464	0.154630439920195	NF-kappa B signaling pathway: XIAP
hsa05152__13	0.105007153452991	DOWN	-1.62244514460464	0.154630439920195	Tuberculosis: LAMP1
hsa05220__6	0.105007153452991	UP	1.62244514460464	0.154630439920195	Chronic myeloid leukemia: TP53
hsa04014__33	0.105607355292921	UP	1.61965264005283	0.155392498508535	Ras signaling pathway: BCL2L1
hsa05161__29	0.10621027557387	DOWN	-1.61686013550101	0.156035268024474	Hepatitis B: NFKB1
hsa05221__5	0.10621027557387	UP	1.61686013550101	0.156035268024474	Acute myeloid leukemia: SPI1
hsa05142__29	0.106815921885337	UP	1.6140676309492	0.156680029057415	Chagas disease (American trypanosomiasis): NOS2
hsa05205__451	0.106815921885337	DOWN	-1.6140676309492	0.156680029057415	Proteoglycans in cancer: KDR**
hsa04960__13	0.107424301808525	DOWN	-1.61127512639738	0.157449503196739	Aldosterone-regulated sodium reabsorption: FXYD4
hsa05152__97	0.108649292772099	UP	1.60569011729375	0.159120827060618	Tuberculosis: IL18
hsa04024__91	0.109265918931466	DOWN	-1.60289761274193	0.159899269215129	cAMP signaling pathway: GRIA1
hsa04072__27	0.112390658051328	DOWN	-1.58893508998286	0.164088614202367	Phospholipase D signaling pathway: C01245
hsa04380__69	0.112390658051328	UP	1.58893508998286	0.164088614202367	Osteoclast differentiation: NFKB2
hsa05168__27	0.112390658051328	UP	1.58893508998286	0.164088614202367	Herpes simplex infection: IRF3
hsa04360__33 134	0.113023980158102	DOWN	-1.58614258543104	0.164885138755492	Axon guidance: NCK1 PAK4
hsa04742__37	0.113659450142633	DOWN	-1.58335008087923	0.165556084430927	Taste transduction: P2RY4
hsa05152__15	0.113660111184617	DOWN	-1.58335008087923	0.165556084430927	Tuberculosis: CTSD
hsa04014__69	0.114940829888279	DOWN	-1.5777650717756	0.167291881766132	Ras signaling pathway: PLCE1*
hsa05134__73	0.115585432483594	DOWN	-1.57497256722378	0.168099866591853	Legionellosis: CXCL1
hsa04068__49	0.11623287383454	DOWN	-1.57218006267197	0.168780193149228	FoxO signaling pathway: BCL2L11
hsa04550__101	0.11623287383454	DOWN	-1.57218006267197	0.168780193149228	Signaling pathways regulating pluripotency of stem cells: ESRRB
hsa04015__27	0.116883161371657	DOWN	-1.56938755812015	0.169462546464	Rap1 signaling pathway: RALA
hsa04920__1	0.116883161371657	UP	1.56938755812015	0.169462546464	Adipocytokine signaling pathway: C00195
hsa04933__65	0.117536302513665	DOWN	-1.56659505356834	0.170278112893737	AGE-RAGE signaling pathway in diabetic complications: COL1A1
hsa04024__59	0.118192304667236	DOWN	-1.56380254901652	0.170964850246141	cAMP signaling pathway: MLLT4
hsa05216__5	0.118192304667236	UP	1.56380254901652	0.170964850246141	Thyroid cancer: MAPK1
hsa04931__104	0.118851175226767	DOWN	-1.56101004446471	0.171653618947806	Insulin resistance: C00369*
hsa05152__6	0.118851175226767	DOWN	-1.56101004446471	0.171653618947806	Tuberculosis: IL10
hsa05321__138	0.119512921574154	UP	1.55821753991289	0.172476789276371	Inflammatory bowel disease (IBD): IFNG**
hsa04666__30 44	0.120177551078563	DOWN	-1.55542503536108	0.173302853780983	Fc gamma R-mediated phagocytosis: C04637 GSN
hsa04620__23	0.120845071096206	UP	1.55263253080926	0.174131816403198	Toll-like receptor signaling pathway: CD40
hsa04910__57	0.122188812029867	UP	1.54704752170563	0.175798451611119	Insulin signaling pathway: GCK
hsa05164__47	0.122188812029867	UP	1.54704752170563	0.175798451611119	Influenza A: CIITA
hsa04666__29	0.122865047591457	DOWN	-1.54425501715382	0.17650108900944	Fc gamma R-mediated phagocytosis: WAS
hsa04917__75	0.122865047591457	UP	1.54425501715382	0.17650108900944	Prolactin signaling pathway: CCND1**
hsa04210__62	0.123544202956959	UP	1.541462512602	0.177070600576756	Apoptosis: TP53AIP1
hsa04910__46	0.123544202956959	DOWN	-1.541462512602	0.177070600576756	Insulin signaling pathway: FBP1
hsa05166__83	0.123544202956959	DOWN	-1.541462512602	0.177070600576756	HTLV-I infection: NFKB2
hsa05032__31	0.12698403141567	UP	1.52749998984292	0.181585232138541	Morphine addiction: GABRR3
hsa05032__33	0.12698403141567	UP	1.52749998984292	0.181585232138541	Morphine addiction: GABRR3*
hsa05032__55	0.12698403141567	UP	1.52749998984292	0.181585232138541	Morphine addiction: GABRR3**
hsa04670__86	0.12838065537921	DOWN	-1.52191498073929	0.183442776773792	Leukocyte transendothelial migration: ACTB
hsa04917__37	0.129083430309431	UP	1.51912247618748	0.184306812729043	Prolactin signaling pathway: TNFSF11
hsa05152__112	0.131209692845336	UP	1.51074496253203	0.187200465342739	Tuberculosis: IFNGR1
hsa04750__44	0.13192441075948	DOWN	-1.50795245798022	0.187934774690722	Inflammatory mediator regulation of TRP channels: TRPA1
hsa04750__63	0.13192441075948	DOWN	-1.50795245798022	0.187934774690722	Inflammatory mediator regulation of TRP channels: TRPA1*
hsa04014__45	0.132642220621816	UP	1.5051599534284	0.188528542018451	Ras signaling pathway: RAB5A
hsa04350__34	0.132642220621816	DOWN	-1.5051599534284	0.188528542018451	TGF-beta signaling pathway: ROCK1
hsa04350__10	0.132642220621816	UP	1.5051599534284	0.188528542018451	TGF-beta signaling pathway: SMAD4
hsa04660__14	0.133363011636923	DOWN	-1.50236744887659	0.189409749709583	T cell receptor signaling pathway: NFKB1
hsa05212__27	0.134086830163613	UP	1.49957494432477	0.190293922868149	Pancreatic cancer: BCL2L1*
hsa05161__130	0.136276521206212	DOWN	-1.49119743066933	0.193255534601111	Hepatitis B: FASLG*
hsa05216__12	0.137689338288415	UP	1.4856124215657	0.195052634254747	Thyroid cancer: CDH1
hsa03320__62	0.1377513814029	UP	1.4856124215657	0.195052634254747	PPAR signaling pathway: UBC
hsa04210__70	0.139238919946327	DOWN	-1.48002741246207	0.196862250247666	Apoptosis: CFLAR*
hsa04662__27	0.139238919946327	DOWN	-1.48002741246207	0.196862250247666	B cell receptor signaling pathway: NFATC1
hsa05152__78	0.139987210771311	UP	1.47723490791025	0.197622816708711	Tuberculosis: IL1A
hsa05219__19	0.139987210771311	DOWN	-1.47723490791025	0.197622816708711	Bladder cancer: TP53
hsa05134__9	0.140738591878506	UP	1.47444240335843	0.198534394999784	Legionellosis: CASP7
hsa04931__77	0.141492139219812	UP	1.47164989880662	0.199299459374432	Insulin resistance: PPP2R4**
hsa04115__50	0.141493070146617	UP	1.47164989880662	0.199299459374432	p53 signaling pathway: RCHY1
hsa03320__36	0.142250652434302	UP	1.4688573942548	0.200066598745549	PPAR signaling pathway: SLC27A4
hsa05132__68	0.142250652434302	UP	1.4688573942548	0.200066598745549	Salmonella infection: NOS2
hsa04010__14	0.143011345579927	DOWN	-1.46606488970299	0.200986027183757	MAPK signaling pathway: MAPT
hsa04662__24	0.14377515640132	DOWN	-1.46327238515117	0.201757669065033	B cell receptor signaling pathway: FOS
hsa04910__26	0.14377515640132	UP	1.46327238515117	0.201757669065033	Insulin signaling pathway: RPS6
hsa04976__41	0.14454196920522	DOWN	-1.46047988059936	0.202531387245262	Bile secretion: CYP7A1
hsa04670__45	0.144542091695528	DOWN	-1.46047988059936	0.202531387245262	Leukocyte transendothelial migration: PXN
hsa03320__23	0.146085362785212	DOWN	-1.45489487149573	0.204388977418773	PPAR signaling pathway: ACADL
hsa05010__49	0.146085362785212	DOWN	-1.45489487149573	0.204388977418773	Alzheimer's disease: EIF2AK3
hsa05142__18	0.146861712068679	DOWN	-1.45210236694391	0.205322289417446	Chagas disease (American trypanosomiasis): FOS
hsa05160__70	0.147641212800454	DOWN	-1.4493098623921	0.20625861624688	Hepatitis C: CDKN1A
hsa04068__60	0.148423871670008	DOWN	-1.44651735784028	0.206890545154263	FoxO signaling pathway: RAG1
hsa04210__64	0.148423871670008	DOWN	-1.44651735784028	0.206890545154263	Apoptosis: TNFRSF10D*
hsa05215__30	0.148423871670008	UP	1.44651735784028	0.206890545154263	Prostate cancer: TP53
hsa04540__22	0.14920965399026	UP	1.44372485328847	0.20767779077958	Gap junction: C00547
hsa04340__17	0.149209695344562	UP	1.44372485328847	0.20767779077958	Hedgehog signaling pathway: SMO
hsa05140__16	0.149998690468837	DOWN	-1.44093234873665	0.208621420718686	Leishmaniasis: STAT1
hsa05223__23	0.15079086366481	DOWN	-1.43813984418484	0.209568071616995	Non-small cell lung cancer: CASP9*
hsa04722__34	0.152384770644544	UP	1.43255483508121	0.211470446116025	Neurotrophin signaling pathway: GSK3B
hsa05205__220	0.152384770644544	DOWN	-1.43255483508121	0.211470446116025	Proteoglycans in cancer: FAS
hsa04350__11	0.15318651755631	UP	1.42976233052939	0.212269518059223	TGF-beta signaling pathway: SMAD4*
hsa05220__25	0.15318651755631	UP	1.42976233052939	0.212269518059223	Chronic myeloid leukemia: BCL2L1*
hsa05321__75	0.153991468795285	DOWN	-1.42696982597758	0.213227685973722	Inflammatory bowel disease (IBD): IL10
hsa05110__14	0.155611010248799	DOWN	-1.42138481687395	0.214836949491178	Vibrio cholerae infection: C00238*
hsa05110__15	0.155611010248799	DOWN	-1.42138481687395	0.214836949491178	Vibrio cholerae infection: C01330
hsa05110__16	0.155611010248799	DOWN	-1.42138481687395	0.214836949491178	Vibrio cholerae infection: C00698
hsa05162__101	0.155611010248799	UP	1.42138481687395	0.214836949491178	Measles: CDKN1B
hsa05200__197	0.156425613399481	DOWN	-1.41859231232213	0.21580303052689	Pathways in cancer: CCND1**
hsa05142__7	0.157238340045864	DOWN	-1.41579980777032	0.216454532191701	Chagas disease (American trypanosomiasis): C1QA
hsa05132__55	0.15724344674916	UP	1.41579980777032	0.216454532191701	Salmonella infection: IL18
hsa05220__22	0.15724344674916	UP	1.41579980777032	0.216454532191701	Chronic myeloid leukemia: CDKN1B
hsa04014__63	0.158064516703965	UP	1.4130073032185	0.217266442492136	Ras signaling pathway: TIAM1*
hsa04662__35	0.158064516703965	DOWN	-1.4130073032185	0.217266442492136	B cell receptor signaling pathway: CD79B
hsa05205__144	0.16054720988052	UP	1.40462978956305	0.220517695442615	Proteoglycans in cancer: NUDT16L1
hsa04261__15 17	0.161381289808843	UP	1.40183728501124	0.221339739818113	Adrenergic signaling in cardiomyocytes: ACTC1 MYH6
hsa04360__6	0.161381289808843	UP	1.40183728501124	0.221339739818113	Axon guidance: MAPK1
hsa04920__31	0.162218637989551	UP	1.39904478045942	0.222325908666934	Adipocytokine signaling pathway: AGRP
hsa05321__122	0.163059260673675	DOWN	-1.39625227590761	0.223315124494049	Inflammatory bowel disease (IBD): IL4**
hsa05110__17	0.16390316408552	DOWN	-1.39345977135579	0.224307389160009	Vibrio cholerae infection: C00698*
hsa05220__50	0.164750354422416	DOWN	-1.39066726680398	0.225302704483057	Chronic myeloid leukemia: MAPK1
hsa04913__47	0.16560083785447	DOWN	-1.38787476225216	0.225808399367597	Ovarian steroidogenesis: INSR
hsa04913__51	0.16560083785447	DOWN	-1.38787476225216	0.225808399367597	Ovarian steroidogenesis: INSR*
hsa05200__80	0.16560083785447	UP	1.38787476225216	0.225808399367597	Pathways in cancer: TP53
hsa05200__52	0.16560083785447	UP	1.38787476225216	0.225808399367597	Pathways in cancer: CDKN1B
hsa04064__94	0.16645462052431	DOWN	-1.38508225770035	0.226643646351578	NF-kappa B signaling pathway: BCL2L1*
hsa05321__95	0.16645462052431	DOWN	-1.38508225770035	0.226643646351578	Inflammatory bowel disease (IBD): SMAD2
hsa04213__54	0.167311708546841	DOWN	-1.38228975314853	0.227645691788207	Longevity regulating pathway - multiple species: SOD2*
hsa04912__43	0.168172108008989	DOWN	-1.37949724859672	0.228650789398619	GnRH signaling pathway: PTK2B
hsa05133__96	0.169035824969454	DOWN	-1.3767047440449	0.229658940793641	Pertussis: IL1B
hsa04014__103	0.173404382293412	DOWN	-1.36274222128583	0.235424013243729	Ras signaling pathway: KSR2
hsa04390__78	0.174288129864062	DOWN	-1.35994971673401	0.236452993512327	Hippo signaling pathway: SOX2
hsa04115__15	0.175175236532452	UP	1.3571572121822	0.237313820796306	p53 signaling pathway: TSC2
hsa04151__73	0.175175236532452	DOWN	-1.3571572121822	0.237313820796306	PI3K-Akt signaling pathway: MAPK1
hsa05012__57	0.179661359102371	UP	1.34319468942312	0.243215917689737	Parkinson's disease: CASP3
hsa04068__48	0.180568741581857	DOWN	-1.3404021848713	0.24426829764745	FoxO signaling pathway: FASLG
hsa05169__64	0.181479523276879	DOWN	-1.33760968031949	0.245323758444069	Epstein-Barr virus infection: NFKB2
hsa05161__214	0.183311306701844	UP	1.33202467121586	0.247621815451305	Hepatitis B: CDKN1B
hsa05014__51	0.184232319545073	UP	1.32923216666404	0.248687161224995	Amyotrophic lateral sclerosis (ALS): DERL1
hsa04012__43	0.187015908589729	UP	1.3208546530086	0.252082419110546	ErbB signaling pathway: PTK2
hsa05321__74	0.187015908589729	UP	1.3208546530086	0.252082419110546	Inflammatory bowel disease (IBD): IL5
hsa04151__33	0.187950639914001	UP	1.31806214845678	0.252979407162183	PI3K-Akt signaling pathway: TP53
hsa04660__30	0.187950639914001	DOWN	-1.31806214845678	0.252979407162183	T cell receptor signaling pathway: CD40LG
hsa04740__10	0.18888881437795	UP	1.31526964390497	0.253878456520864	Olfactory transduction: ANO2
hsa05161__26	0.18888881437795	UP	1.31526964390497	0.253878456520864	Hepatitis B: MMP9
hsa04064__93	0.189830437321716	UP	1.31247713935315	0.254779565519646	NF-kappa B signaling pathway: PLAU
hsa05211__23	0.189830437321716	UP	1.31247713935315	0.254779565519646	Renal cell carcinoma: PDGFB
hsa04961__17	0.190775514051183	UP	1.30968463480134	0.255865232621108	Endocrine and other factor-regulated calcium reabsorption: CALB1
hsa04920__5	0.191724049837734	DOWN	-1.30689213024952	0.256953986908061	Adipocytokine signaling pathway: NFKBIA
hsa04066__49	0.192676049917998	DOWN	-1.30409962569771	0.257678503769337	HIF-1 signaling pathway: EPO
hsa04360__59	0.192676049917998	UP	1.30409962569771	0.257678503769337	Axon guidance: MAPK1*
hsa04670__35	0.192676049917998	DOWN	-1.30409962569771	0.257678503769337	Leukocyte transendothelial migration: PTK2
hsa05205__188	0.193631519493603	UP	1.30130712114589	0.258772137360228	Proteoglycans in cancer: TNF
hsa04360__29	0.194590463730923	UP	1.29851461659408	0.259684290731821	Axon guidance: RASA1
hsa04550__62 63	0.194590463730923	DOWN	-1.29851461659408	0.259684290731821	Signaling pathways regulating pluripotency of stem cells: SMAD2 SMAD4
hsa04064__142	0.196518796678448	DOWN	-1.29292960749045	0.261885687204826	NF-kappa B signaling pathway: NFKB2*
hsa04923__31	0.196518796678448	DOWN	-1.29292960749045	0.261885687204826	Regulation of lipolysis in adipocytes: PRKACA*
hsa04210__99	0.197488195542899	UP	1.29013710293863	0.262991013058191	Apoptosis: BID**
hsa05222__39	0.198461089377056	UP	1.28734459838682	0.264099424178108	Small cell lung cancer: BCL2L1
hsa05205__319	0.199437483167296	DOWN	-1.284552093835	0.265210920644974	Proteoglycans in cancer: KDR
hsa04650__40	0.200417381863249	UP	1.28175958928318	0.266325502490131	Natural killer cell mediated cytotoxicity: TNFRSF10D
hsa04010__107	0.202387713585607	DOWN	-1.27617458017955	0.268753720019332	MAPK signaling pathway: MAP3K2
hsa04210__4	0.204372123396848	DOWN	-1.27058957107592	0.270814682554779	Apoptosis: DFFA
hsa04921__67	0.204372123396848	DOWN	-1.27058957107592	0.270814682554779	Oxytocin signaling pathway: RYR1
hsa05152__68	0.204372123396848	UP	1.27058957107592	0.270814682554779	Tuberculosis: CD74
hsa05166__53 146	0.205369619562396	DOWN	-1.26779706652411	0.271944690033645	HTLV-I infection: CREB1 CRTC2
hsa04810__32	0.206370649545918	UP	1.26500456197229	0.273077782039986	Regulation of actin cytoskeleton: PXN
hsa04919__30	0.207375218032897	DOWN	-1.26221205742048	0.274213958257434	Thyroid hormone signaling pathway: MYH6
hsa05166__32	0.2104102007871	DOWN	-1.25383454376503	0.278031481912068	HTLV-I infection: STAT5A
hsa04668__153	0.211428969364615	UP	1.25104203921322	0.279181330594597	TNF signaling pathway: MAPK14*
hsa05160__22 23	0.212451299287267	UP	1.2482495346614	0.28033426359605	Hepatitis C: STAT1 IRF9
hsa05014__13	0.21347719500453	UP	1.24545703010959	0.281490280290184	Amyotrophic lateral sclerosis (ALS): CASP3
hsa04115__64	0.21450666092569	UP	1.24266452555777	0.282649379999559	p53 signaling pathway: PMAIP1
hsa04530__4 53	0.215539701419597	UP	1.23987202100596	0.283612814402958	Tight junction: OCLN OCLN
hsa04530__4 45	0.215539701419597	UP	1.23987202100596	0.283612814402958	Tight junction: OCLN TJP2
hsa04012__35	0.216576320814427	DOWN	-1.23707951645414	0.284379389804548	ErbB signaling pathway: CBLC
hsa05161__48	0.216576320814427	DOWN	-1.23707951645414	0.284379389804548	Hepatitis B: STAT1
hsa05200__193	0.216576320814427	DOWN	-1.23707951645414	0.284379389804548	Pathways in cancer: NOS2
hsa04370__37	0.217616523397436	DOWN	-1.23428701190233	0.285346439262932	VEGF signaling pathway: CASP9
hsa04670__76	0.217616523397436	DOWN	-1.23428701190233	0.285346439262932	Leukocyte transendothelial migration: CDC42
hsa05168__138	0.218660313414718	DOWN	-1.23149450735051	0.286315490527007	Herpes simplex infection: CHUK
hsa05205__400	0.218660313414718	DOWN	-1.23149450735051	0.286315490527007	Proteoglycans in cancer: ITGA2*
hsa04015__18	0.219707695070966	UP	1.2287020027987	0.287486601001633	Rap1 signaling pathway: CDH1
hsa04210__57	0.22075867252923	UP	1.22590949824688	0.288460045676233	Apoptosis: BAK1
hsa04261__23	0.22075867252923	DOWN	-1.22590949824688	0.288460045676233	Adrenergic signaling in cardiomyocytes: SLC9A1
hsa04740__33	0.223933220716892	DOWN	-1.21753198459143	0.292404810095232	Olfactory transduction: CNGA3*
hsa03320__56	0.224998622172415	DOWN	-1.21473948003962	0.293388210313649	PPAR signaling pathway: FADS2
hsa04151__34	0.224998622172415	DOWN	-1.21473948003962	0.293388210313649	PI3K-Akt signaling pathway: GYS1
hsa05222__40	0.226067639612135	UP	1.2119469754878	0.294577735666575	Small cell lung cancer: TRAF1
hsa05145__33	0.2271402769442	DOWN	-1.20915447093599	0.295360955278997	Toxoplasmosis: STAT3
hsa05162__44	0.2271402769442	DOWN	-1.20915447093599	0.295360955278997	Measles: PRKCQ
hsa05169__125	0.2271402769442	DOWN	-1.20915447093599	0.295360955278997	Epstein-Barr virus infection: STAT3
hsa05200__207	0.228216538033441	DOWN	-1.20636196638417	0.296555238564894	Pathways in cancer: CDK4
hsa04742__23 45	0.229295527025214	UP	1.20356946183236	0.297546951499609	Taste transduction: PKD1L3 PKD2L1
hsa04921__60	0.229296426701135	UP	1.20356946183236	0.297546951499609	Oxytocin signaling pathway: ELK1
hsa05164__19	0.230379946724767	DOWN	-1.20077695728054	0.29874666659478	Influenza A: NFKB1
hsa04742__67	0.231467101837792	DOWN	-1.19798445272873	0.299742718368857	Taste transduction: PRKACA
hsa05162__81	0.231467101837792	UP	1.19798445272873	0.299742718368857	Measles: TNFRSF10D
hsa04340__49	0.233652332044302	DOWN	-1.1923994436251	0.302364140434741	Hedgehog signaling pathway: CCND1
hsa04930__13	0.234750414382447	UP	1.18960693907328	0.303576069253007	Type II diabetes mellitus: C00162
hsa04724__33 70 69	0.23585214629884	UP	1.18681443452147	0.304581569000357	Glutamatergic synapse: ITPR1 HOMER3 HOMER3
hsa04910__14	0.23585214629884	DOWN	-1.18681443452147	0.304581569000357	Insulin signaling pathway: C00369
hsa04360__58	0.236957531303279	UP	1.18402192996965	0.305589019436419	Axon guidance: PLXNC1
hsa04912__15	0.236957531303279	DOWN	-1.18402192996965	0.305589019436419	GnRH signaling pathway: CAMK2A
hsa04064__137	0.239179274388118	UP	1.17843692086602	0.308031430140695	NF-kappa B signaling pathway: ICAM1
hsa05210__39	0.239179274388118	UP	1.17843692086602	0.308031430140695	Colorectal cancer: BAD
hsa04920__3	0.241415670802588	DOWN	-1.17285191176239	0.310698661258947	Adipocytokine signaling pathway: C15493
hsa05200__65	0.242539372296104	UP	1.17005940721058	0.311931198182327	Pathways in cancer: STK4
hsa04976__95 96	0.24366612377601	DOWN	-1.16726690265876	0.313165968929632	Bile secretion: SLC51A SLC51B
hsa05200__219	0.24821304056648	DOWN	-1.1560968844515	0.318791731527284	Pathways in cancer: MYC**
hsa04072__57	0.250508307086507	UP	1.15051187534787	0.321519883207341	Phospholipase D signaling pathway: C06124
hsa04668__128	0.253978922609931	UP	1.14213436169242	0.325751805859426	TNF signaling pathway: CHUK*
hsa04014__62	0.256311176170149	DOWN	-1.13654935258879	0.327847991847318	Ras signaling pathway: RASSF5
hsa04115__16	0.256311176170149	UP	1.13654935258879	0.327847991847318	p53 signaling pathway: PPM1D
hsa04912__19	0.256311176170149	DOWN	-1.13654935258879	0.327847991847318	GnRH signaling pathway: MAPK7
hsa04919__42	0.256311176170149	DOWN	-1.13654935258879	0.327847991847318	Thyroid hormone signaling pathway: SLC2A1
hsa04933__57	0.257482864032731	DOWN	-1.13375684803698	0.328675476574389	AGE-RAGE signaling pathway in diabetic complications: FIGF
hsa05200__129 130	0.257482864032731	UP	1.13375684803698	0.328675476574389	Pathways in cancer: CTBP1 HDAC1
hsa05220__12 13	0.257482864032731	UP	1.13375684803698	0.328675476574389	Chronic myeloid leukemia: HDAC1 CTBP1
hsa04115__27	0.258658262777045	DOWN	-1.13096434348516	0.329504322547842	p53 signaling pathway: THBS1
hsa04622__6	0.258658262777045	DOWN	-1.13096434348516	0.329504322547842	RIG-I-like receptor signaling pathway: NFKB1
hsa04650__110 111	0.258658262777045	DOWN	-1.13096434348516	0.329504322547842	Natural killer cell mediated cytotoxicity: ITGAL ITGB2
hsa04670__10	0.259837374961075	DOWN	-1.12817183893335	0.330782132487709	Leukocyte transendothelial migration: BCAR1
hsa04540__12	0.261020154606483	UP	1.12537933438153	0.33161390237425	Gap junction: C00025
hsa04725__43	0.261020203092877	UP	1.12537933438153	0.33161390237425	Cholinergic synapse: CREB3
hsa05132__41	0.261020203092877	DOWN	-1.12537933438153	0.33161390237425	Salmonella infection: ACTB*
hsa05200__225	0.26819534089325	UP	1.10862430707064	0.340269443307506	Pathways in cancer: PPARD
hsa05221__11	0.26819534089325	UP	1.10862430707064	0.340269443307506	Acute myeloid leukemia: PPARD
hsa04360__51	0.26940424664616	DOWN	-1.10583180251883	0.341572590720738	Axon guidance: FYN
hsa04064__114	0.270616886588228	DOWN	-1.10303929796701	0.342878712002212	NF-kappa B signaling pathway: BCL2A1*
hsa05200__204	0.273053377184218	DOWN	-1.09745428886338	0.345732679062766	Pathways in cancer: TGFB1*
hsa04742__55	0.274274304064107	DOWN	-1.09466178431157	0.346814884599343	Taste transduction: P2RX3
hsa04620__87	0.274277231780002	DOWN	-1.09466178431157	0.346814884599343	Toll-like receptor signaling pathway: CCL4L1
hsa04530__7 52	0.27550482844826	UP	1.09186927975975	0.348132866613504	Tight junction: PARD6A MPP5
hsa05213__13	0.276736169028671	DOWN	-1.08907677520793	0.349453804841984	Endometrial cancer: CASP9
hsa04723__46	0.277971255308046	UP	1.08628427065612	0.350777695583491	Retrograde endocannabinoid signaling: ADCY1
hsa04662__16	0.279210089020125	UP	1.0834917661043	0.352104535079742	B cell receptor signaling pathway: VAV3
hsa04152__30	0.280452671845374	UP	1.08069926155249	0.353197433242264	AMPK signaling pathway: ACACA
hsa04912__26	0.280452671845374	DOWN	-1.08069926155249	0.353197433242264	GnRH signaling pathway: PLD1
hsa04510__20 69	0.281699005410785	DOWN	-1.07790675700067	0.354529424760123	Focal adhesion: VASP ACTB
hsa05168__91 92	0.285460526011598	UP	1.06952924334523	0.359022977493837	Herpes simplex infection: STAT1 IRF9
hsa04921__76	0.286721877731114	UP	1.06673673879341	0.3601272782465	Oxytocin signaling pathway: CDKN1A
hsa05132__54	0.286721877731114	UP	1.06673673879341	0.3601272782465	Salmonella infection: IL1B
hsa04932__138	0.287986987516682	UP	1.0639442342416	0.360751699695896	Non-alcoholic fatty liver disease (NAFLD): CEBPA
hsa05150__69	0.287986987516682	UP	1.0639442342416	0.360751699695896	Staphylococcus aureus infection: FPR2
hsa05211__42	0.287986987516682	UP	1.0639442342416	0.360751699695896	Renal cell carcinoma: SLC2A1*
hsa05321__81	0.287986987516682	DOWN	-1.0639442342416	0.360751699695896	Inflammatory bowel disease (IBD): IL13
hsa04068__13	0.290528486439076	DOWN	-1.05835922513797	0.363208932813721	FoxO signaling pathway: PCK1
hsa04510__43	0.290528486439076	UP	1.05835922513797	0.363208932813721	Focal adhesion: BAD
hsa04666__23	0.290528486439076	UP	1.05835922513797	0.363208932813721	Fc gamma R-mediated phagocytosis: RPS6KB1
hsa04064__25	0.291804878015139	DOWN	-1.05556672058615	0.36407793213177	NF-kappa B signaling pathway: NFKB2
hsa04370__15	0.291804878015139	UP	1.05556672058615	0.36407793213177	VEGF signaling pathway: PLA2G4B
hsa04650__25	0.291804878015139	DOWN	-1.05556672058615	0.36407793213177	Natural killer cell mediated cytotoxicity: SH2D1B
hsa05110__13	0.296947887820114	DOWN	-1.04439670237889	0.370003614319672	Vibrio cholerae infection: C00238
hsa04911__24	0.296948084297002	DOWN	-1.04439670237889	0.370003614319672	Insulin secretion: INS
hsa03320__41	0.29954228519871	DOWN	-1.03881169327526	0.372741691316805	PPAR signaling pathway: ANGPTL4
hsa04151__27	0.29954228519871	DOWN	-1.03881169327526	0.372741691316805	PI3K-Akt signaling pathway: FASLG
hsa04918__14	0.300845038141168	DOWN	-1.03601918872345	0.374115040812213	Thyroid hormone synthesis: DUOX2
hsa05016__60	0.302151560423532	UP	1.03322668417163	0.374995232520354	Huntington's disease: CASP3*
hsa05134__35	0.302151560423532	UP	1.03322668417163	0.374995232520354	Legionellosis: CASP3
hsa05218__9	0.302151560423532	UP	1.03322668417163	0.374995232520354	Melanoma: CCND1
hsa04931__47	0.304775915704188	UP	1.027641675068	0.378002604361828	Insulin resistance: AKT2*
hsa05152__77	0.306093749908167	UP	1.02484917051618	0.379136556412291	Tuberculosis: IL12A
hsa05211__41	0.306093749908167	UP	1.02484917051618	0.379136556412291	Renal cell carcinoma: PDGFB*
hsa05212__12	0.310069884806515	DOWN	-1.01647165686074	0.383808506950884	Pancreatic cancer: CASP9
hsa05160__8	0.311402808541329	DOWN	-1.01367915230892	0.385204659150202	Hepatitis C: NFKB1
hsa04620__86	0.314079975968425	DOWN	-1.00809414320529	0.388260707134652	Toll-like receptor signaling pathway: IL12A
hsa04520__73	0.316772237901672	DOWN	-1.00250913410166	0.390817488520841	Adherens junction: PARD3
hsa05160__58	0.316772237901672	DOWN	-1.00250913410166	0.390817488520841	Hepatitis C: EIF3E
hsa05200__220	0.316772237901672	DOWN	-1.00250913410166	0.390817488520841	Pathways in cancer: CSF1R*
hsa05010__51	0.320838934179709	DOWN	-0.994131620446218	0.395575037613959	Alzheimer's disease: ATF6
hsa04950__30	0.322202046972163	UP	0.991339115894402	0.396735023761923	Maturity onset diabetes of the young: PAX6*
hsa05133__94	0.322202046972163	DOWN	-0.991339115894402	0.396735023761923	Pertussis: IL12A
hsa05120__19	0.323568933191631	UP	0.988546611342587	0.398157187601228	Epithelial cell signaling in Helicobacter pylori infection: CXCL1
hsa04151__110	0.326314024880864	UP	0.982961602238957	0.4012722858319	PI3K-Akt signaling pathway: BCL2**
hsa04623__17	0.327692229686103	UP	0.980169097687141	0.402703531445512	Cytosolic DNA-sensing pathway: NFKB1
hsa04930__10	0.329074206588992	UP	0.977376593135326	0.404137538680206	Type II diabetes mellitus: C00031
hsa05133__30	0.330459955107411	UP	0.974584088583511	0.405574301532871	Pertussis: NOS2
hsa04066__62	0.331849474699026	DOWN	-0.971791584031696	0.407013813942213	HIF-1 signaling pathway: NPPA
hsa04064__128	0.334639824630496	DOWN	-0.966206574928065	0.410168447802154	NF-kappa B signaling pathway: IL1B*
hsa04973__5	0.341681643618389	UP	0.952244052168989	0.418526602580804	Carbohydrate digestion and absorption: SLC2A5
hsa04933__27	0.343101304995958	UP	0.949451547617174	0.419991760317528	AGE-RAGE signaling pathway in diabetic complications: TNF
hsa04115__40	0.345951916972029	DOWN	-0.943866538513544	0.422930157443358	p53 signaling pathway: PIDD1
hsa04917__44	0.345951916972029	DOWN	-0.943866538513544	0.422930157443358	Prolactin signaling pathway: PRLR**
hsa05231__18	0.347382865203524	UP	0.941074033961728	0.424127617750112	Choline metabolism in cancer: CHKA
hsa05231__17	0.347382865203524	UP	0.941074033961728	0.424127617750112	Choline metabolism in cancer: SLC44A3
hsa04014__54	0.348817573249519	DOWN	-0.938281529409913	0.425326554273749	Ras signaling pathway: RHOA
hsa04723__67	0.348817573249519	DOWN	-0.938281529409913	0.425326554273749	Retrograde endocannabinoid signaling: PRKACA
hsa04115__25	0.353144242579285	UP	0.929904015754467	0.430322977825212	p53 signaling pathway: CD82
hsa05162__62	0.354593975876541	UP	0.927111511202652	0.431809514369423	Measles: IL12A
hsa05215__22	0.355075035098357	UP	0.815411329130044	0.432115279112573	Prostate cancer: C16038
hsa05131__12	0.356047461672957	UP	0.924319006650837	0.432738150377417	Shigellosis: ARPC5
hsa05205__69	0.356047461672957	UP	0.924319006650837	0.432738150377417	Proteoglycans in cancer: MAPK1*
hsa04930__15	0.357504698317841	DOWN	-0.921526502099022	0.433947886394847	Type II diabetes mellitus: C00031*
hsa05120__52	0.357504698317841	DOWN	-0.921526502099022	0.433947886394847	Epithelial cell signaling in Helicobacter pylori infection: LYN
hsa04024__107 64	0.358965684097665	UP	0.918733997547207	0.435439974447716	cAMP signaling pathway: NFKBIA NFKB1
hsa04014__68	0.366326785633835	DOWN	-0.90477147478813	0.443224745786205	Ras signaling pathway: RALGDS*
hsa04024__21	0.366326785633835	DOWN	-0.90477147478813	0.443224745786205	cAMP signaling pathway: AKT3
hsa05161__68	0.366326785633835	DOWN	-0.90477147478813	0.443224745786205	Hepatitis B: JUN
hsa05205__183	0.366326785633835	UP	0.90477147478813	0.443224745786205	Proteoglycans in cancer: VEGFA*
hsa04727__49	0.369297305790458	UP	0.8991864656845	0.446244257565756	GABAergic synapse: GABRR3
hsa04932__95	0.369297403147818	UP	0.8991864656845	0.446244257565756	Non-alcoholic fatty liver disease (NAFLD): IL1A
hsa04360__20	0.370788312740688	DOWN	-0.896393961132685	0.447757866092386	Axon guidance: ROCK1
hsa05160__56	0.372282953199684	DOWN	-0.89360145658087	0.448985666920543	Hepatitis C: MAPK1
hsa05200__49	0.372282953199684	DOWN	-0.89360145658087	0.448985666920543	Pathways in cancer: CASP9
hsa05160__71	0.373781322176519	DOWN	-0.890808952029054	0.450503594849056	Hepatitis C: MAPK8
hsa04620__46	0.376789235970051	UP	0.885223942925424	0.453547068794187	Toll-like receptor signaling pathway: TNF
hsa05133__60	0.376789235970051	DOWN	-0.885223942925424	0.453547068794187	Pertussis: C5
hsa05150__35	0.378298096944528	DOWN	-0.882431438373609	0.454781445726568	Staphylococcus aureus infection: FCAR
hsa04920__37	0.378298775769359	DOWN	-0.882431438373609	0.454781445726568	Adipocytokine signaling pathway: IRS1
hsa05142__53	0.379812034051526	DOWN	-0.879638933821794	0.456017132257391	Chagas disease (American trypanosomiasis): AKT3
hsa05219__10	0.379812034051526	DOWN	-0.879638933821794	0.456017132257391	Bladder cancer: EGFR
hsa05152__88 89	0.381329008146847	DOWN	-0.876846429269978	0.457546108753464	Tuberculosis: ITGAX ITGB2
hsa05215__14	0.384374092775144	DOWN	-0.871261420166348	0.460905501164324	Prostate cancer: CCND1
hsa04933__59	0.385902197645441	DOWN	-0.868468915614533	0.462442748326392	AGE-RAGE signaling pathway in diabetic complications: SERPINE1
hsa05164__53	0.388969517855347	DOWN	-0.862883906510902	0.465821366507455	Influenza A: MAPK14
hsa04662__32 51	0.390508727142877	UP	0.860091401959087	0.467069317823976	B cell receptor signaling pathway: BLNK GRB2
hsa04670__54	0.390508727142877	DOWN	-0.860091401959087	0.467069317823976	Leukocyte transendothelial migration: RAC1*
hsa05205__189	0.392051631742267	UP	0.857298897407272	0.468616422419669	Proteoglycans in cancer: IL12B
hsa05215__35	0.393598228464641	DOWN	-0.854506392855457	0.470165970302009	Prostate cancer: CASP9
hsa04010__117	0.395148514055843	UP	0.851713888303641	0.471119326085615	MAPK signaling pathway: JUND
hsa04510__19 23	0.395148514055843	UP	0.851713888303641	0.471119326085615	Focal adhesion: VCL TLN1
hsa04620__76	0.395148514055843	DOWN	-0.851713888303641	0.471119326085615	Toll-like receptor signaling pathway: CCL3L3
hsa04530__22 33	0.396702485196354	UP	0.848921383751826	0.47267214310967	Tight junction: MYL12B CGN
hsa04921__28	0.39982147051995	UP	0.843336374648196	0.475785017800498	Oxytocin signaling pathway: EEF2
hsa05161__31	0.39982147051995	DOWN	-0.843336374648196	0.475785017800498	Hepatitis B: ELK1
hsa05150__66	0.401386477736494	DOWN	-0.840543870096381	0.477345058017008	Staphylococcus aureus infection: IL10
hsa04350__50	0.402955156569119	UP	0.837751365544565	0.478907488420856	TGF-beta signaling pathway: AMHR2
hsa04010__129	0.404527503370363	UP	0.83495886099275	0.480168780058694	MAPK signaling pathway: FOS
hsa04723__7	0.404527503370363	DOWN	-0.83495886099275	0.480168780058694	Retrograde endocannabinoid signaling: ITPR1
hsa05200__191	0.407683185959791	UP	0.82937385188912	0.483303915721417	Pathways in cancer: CCND1*
hsa05321__123	0.407683185959791	DOWN	-0.82937385188912	0.483303915721417	Inflammatory bowel disease (IBD): IL5*
hsa04360__101 103	0.41563631387896	DOWN	-0.815411329130044	0.49242158498018	Axon guidance: DPYSL2 DPYSL5
hsa04015__92	0.417237486314745	UP	0.812618824578228	0.4936964412665	Rap1 signaling pathway: C00076*
hsa04015__11	0.417237865210858	DOWN	-0.812618824578228	0.4936964412665	Rap1 signaling pathway: RAC1
hsa04210__10	0.41884304871556	DOWN	-0.809826320026413	0.495283882024253	Apoptosis: BIRC2
hsa04064__96	0.420451860084821	DOWN	-0.807033815474598	0.49687361327005	NF-kappa B signaling pathway: BCL2A1
hsa04115__30	0.423680348852082	UP	0.801448806370967	0.500374214640516	p53 signaling pathway: SERPINE1
hsa04510__19 26	0.426923295718207	UP	0.795863797267337	0.503571169274646	Focal adhesion: VCL ACTN4
hsa05133__27	0.426923295718207	DOWN	-0.795863797267337	0.503571169274646	Pertussis: IRF3
hsa05223__8	0.428550179461611	DOWN	-0.793071292715522	0.505173015814534	Non-small cell lung cancer: CASP9
hsa04750__90	0.430180663824501	DOWN	-0.790278788163707	0.506142434142917	Inflammatory mediator regulation of TRP channels: C01245**
hsa04923__43	0.430180663824501	DOWN	-0.790278788163707	0.506142434142917	Regulation of lipolysis in adipocytes: C00219
hsa04924__30	0.430180663824501	UP	0.790278788163707	0.506142434142917	Renin secretion: PDE3A
hsa03320__59	0.433452415246711	DOWN	-0.784693779060076	0.509672771119256	PPAR signaling pathway: NR1H3
hsa05211__4	0.435093672558303	UP	0.781901274508261	0.510963131710657	Renal cell carcinoma: SLC2A1
hsa05321__19	0.435093672558303	UP	0.781901274508261	0.510963131710657	Inflammatory bowel disease (IBD): TNF
hsa04310__36	0.436738510993861	DOWN	-0.779108769956446	0.512574429829772	Wnt signaling pathway: MYC
hsa05145__13	0.440038911007216	UP	0.773523760852815	0.516125539190112	Toxoplasmosis: GNAI1
hsa04062__35 36 37	0.441694462303175	DOWN	-0.770731256301	0.517421380715502	Chemokine signaling pathway: PARD3 PRKCZ TIAM1
hsa05200__96	0.441694462303175	DOWN	-0.770731256301	0.517421380715502	Pathways in cancer: C00416
hsa04933__22	0.445016241267786	DOWN	-0.76514624719737	0.520663460362496	AGE-RAGE signaling pathway in diabetic complications: EDN1
hsa05161__69	0.445016241267786	UP	0.76514624719737	0.520663460362496	Hepatitis B: SMAD4
hsa04024__76	0.446682458253492	DOWN	-0.762353742645554	0.522287703209901	cAMP signaling pathway: C00416
hsa04370__25	0.451702353721671	DOWN	-0.753976228990109	0.527500759877576	VEGF signaling pathway: PXN
hsa05142__84	0.451702353721671	DOWN	-0.753976228990109	0.527500759877576	Chagas disease (American trypanosomiasis): NFKB1*
hsa04012__23	0.45506659853575	DOWN	-0.748391219886478	0.531099464999176	ErbB signaling pathway: RPS6KB1
hsa04742__47	0.4601393226494	DOWN	-0.740013706231033	0.536686398049797	Taste transduction: GABRA1
hsa05161__78	0.461837235617262	DOWN	-0.737221201679217	0.537998862817628	Hepatitis B: TNF
hsa05169__32	0.461837235617262	DOWN	-0.737221201679217	0.537998862817628	Epstein-Barr virus infection: CR2
hsa05200__66	0.468663750509963	UP	0.726051183471957	0.545612879311165	Pathways in cancer: CCND1
hsa05152__129	0.472097838570795	UP	0.720466174368326	0.549270488343358	Tuberculosis: IFNB1
hsa04064__52	0.473820067986752	DOWN	-0.717673669816511	0.550592398112001	NF-kappa B signaling pathway: TRAF1
hsa04310__34	0.473820067986752	DOWN	-0.717673669816511	0.550592398112001	Wnt signaling pathway: FOSL1
hsa04014__97	0.480743402141132	UP	0.70650365160925	0.557602995446412	Ras signaling pathway: PAK4
hsa04666__40	0.480743402141132	DOWN	-0.70650365160925	0.557602995446412	Fc gamma R-mediated phagocytosis: PLA2G6
hsa04971__56	0.480743402141132	DOWN	-0.70650365160925	0.557602995446412	Gastric acid secretion: CAMK2A
hsa05142__49	0.482482806402481	DOWN	-0.703711147057435	0.558930452053182	Chagas disease (American trypanosomiasis): ADCY1
hsa05205__121	0.482482806402481	DOWN	-0.703711147057435	0.558930452053182	Proteoglycans in cancer: PLAUR
hsa05152__126	0.484225625359144	UP	0.70091864250562	0.560603789309816	Tuberculosis: NOS2
hsa04014__64	0.489474500930102	DOWN	-0.692541128850174	0.56633164239388	Ras signaling pathway: PIK3R5*
hsa04950__8	0.492990696256985	UP	0.686956119746544	0.570048934318076	Maturity onset diabetes of the young: NEUROD1
hsa04151__28	0.494753855863141	DOWN	-0.684163615194728	0.571033473689706	PI3K-Akt signaling pathway: BCL2L11
hsa04350__21	0.494753855863141	DOWN	-0.684163615194728	0.571033473689706	TGF-beta signaling pathway: CDKN2B
hsa04666__20	0.494753855863141	DOWN	-0.684163615194728	0.571033473689706	Fc gamma R-mediated phagocytosis: PLA2G4B
hsa04950__16	0.498290262393399	UP	0.678578606091098	0.573705516566909	Maturity onset diabetes of the young: PAX4
hsa05200__223	0.498290262393399	UP	0.678578606091098	0.573705516566909	Pathways in cancer: CCND1****
hsa05216__14	0.498290262393399	UP	0.678578606091098	0.573705516566909	Thyroid cancer: MAPK1*
hsa05221__17	0.498290262393399	UP	0.678578606091098	0.573705516566909	Acute myeloid leukemia: CCND1
hsa04360__31	0.505403215761519	UP	0.667408587883837	0.581538666513101	Axon guidance: CDC42*
hsa04022__19	0.50718977235934	UP	0.664616083332022	0.58288047844844	cGMP-PKG signaling pathway: CNGB1
hsa04931__137	0.50718977235934	UP	0.664616083332022	0.58288047844844	Insulin resistance: MLXIP*
hsa04064__2	0.508979640803042	DOWN	-0.661823578780207	0.584579917523787	NF-kappa B signaling pathway: BCL2L1
hsa04910__32	0.514369038439358	DOWN	-0.653446065124761	0.590408932942917	Insulin signaling pathway: EIF4E
hsa04360__96	0.516172075166482	UP	0.650653560572946	0.59139471294989	Axon guidance: GSK3B
hsa04917__65	0.516172075166482	UP	0.650653560572946	0.59139471294989	Prolactin signaling pathway: CYP17A1
hsa05160__12 13 14	0.516172075166482	UP	0.650653560572946	0.59139471294989	Hepatitis C: IKBKG CHUK IKBKB
hsa05161__10	0.517978383859639	DOWN	-0.647861056021131	0.593102610159818	Hepatitis B: CASP3
hsa03320__46	0.523416859670678	DOWN	-0.639483542365685	0.598964847333254	PPAR signaling pathway: APOA2
hsa04024__25	0.525236173835052	UP	0.63669103781387	0.60031555391488	cAMP signaling pathway: CFTR
hsa04740__39	0.525236173835052	DOWN	-0.63669103781387	0.60031555391488	Olfactory transduction: PRKG1*
hsa04724__26	0.528884484987043	DOWN	-0.631106028710239	0.604117901088543	Glutamatergic synapse: PRKACA
hsa04150__33	0.530713464906474	DOWN	-0.628313524158424	0.605103519756835	mTOR signaling pathway: RPS6
hsa04370__16	0.530713464906474	DOWN	-0.628313524158424	0.605103519756835	VEGF signaling pathway: HSPB1
hsa04922__36	0.530713464906474	UP	0.628313524158424	0.605103519756835	Glucagon signaling pathway: GYS1
hsa04530__11 33	0.532545649567285	DOWN	-0.625521019606609	0.60682430293325	Tight junction: TJP1 CGN
hsa05166__99	0.534381030272334	DOWN	-0.622728515054794	0.608546639928312	HTLV-I infection: JUN
hsa04976__16	0.536219598259417	DOWN	-0.619936010502978	0.610270517946363	Bile secretion: CFTR
hsa05231__34	0.538061344701364	UP	0.617143505951163	0.611995924148828	Choline metabolism in cancer: PLD1
hsa04020__7	0.539906260706128	DOWN	-0.614351001399348	0.613722845654455	Calcium signaling pathway: ADCY1
hsa05130__55	0.541754337316885	UP	0.611558496847533	0.615451269539557	Pathogenic Escherichia coli infection: ACTB
hsa04727__17 37	0.543605565512132	UP	0.608765992295717	0.617181182838245	GABAergic synapse: GABRA1 GPHN
hsa04024__77	0.547317440247287	DOWN	-0.603180983192087	0.620271091812215	cAMP signaling pathway: RHOA*
hsa04210__72	0.547317440247287	DOWN	-0.603180983192087	0.620271091812215	Apoptosis: BCL2A1
hsa05200__48	0.547317440247287	DOWN	-0.603180983192087	0.620271091812215	Pathways in cancer: MTOR
hsa04917__40	0.549178068421706	UP	0.600388478640272	0.622004575385404	Prolactin signaling pathway: TH
hsa04014__37	0.554778604629875	DOWN	-0.592010964984826	0.626836439025578	Ras signaling pathway: FASLG
hsa04064__53	0.554778604629875	DOWN	-0.592010964984826	0.626836439025578	NF-kappa B signaling pathway: CXCL8
hsa04550__9	0.554778604629875	DOWN	-0.592010964984826	0.626836439025578	Signaling pathways regulating pluripotency of stem cells: HNF1A
hsa04611__25	0.554778604629875	DOWN	-0.592010964984826	0.626836439025578	Platelet activation: ORAI1
hsa05222__19	0.558527744272751	DOWN	-0.586425955881196	0.630693288154146	Small cell lung cancer: CASP9
hsa04728__54	0.562289153842873	DOWN	-0.580840946777565	0.633798032435968	Dopaminergic synapse: CAMK2A
hsa05205__113	0.562289153842873	DOWN	-0.580840946777565	0.633798032435968	Proteoglycans in cancer: TP53
hsa05210__23	0.562289153842873	UP	0.580840946777565	0.633798032435968	Colorectal cancer: CCND1
hsa05169__103	0.564174435655034	DOWN	-0.57804844222575	0.635541825297248	Epstein-Barr virus infection: NFKB1*
hsa03320__30	0.566062755787463	DOWN	-0.575255937673935	0.636524187986023	PPAR signaling pathway: LPL
hsa04110__48	0.566062755787463	UP	0.575255937673935	0.636524187986023	Cell cycle: RB1*
hsa04115__23	0.566062755787463	UP	0.575255937673935	0.636524187986023	p53 signaling pathway: PTEN
hsa04670__55	0.567954104387778	DOWN	-0.57246343312212	0.638268996497988	Leukocyte transendothelial migration: RAC2
hsa03320__63	0.569848471540527	DOWN	-0.569670928570304	0.640015109399073	PPAR signaling pathway: DBI
hsa05162__78	0.571745847267315	DOWN	-0.566878424018489	0.641762513151305	Measles: FAS
hsa04612__18	0.573646221526943	UP	0.564085919466674	0.642743738967875	Antigen processing and presentation: KIR2DS2
hsa04621__34 35	0.573646221526943	DOWN	-0.564085919466674	0.642743738967875	NOD-like receptor signaling pathway: CASP1 PYCARD
hsa04912__14	0.573646221526943	DOWN	-0.564085919466674	0.642743738967875	GnRH signaling pathway: ATF4
hsa04520__18	0.577455925166705	UP	0.558500910363044	0.646241622029922	Adherens junction: SNAI2
hsa05321__46	0.577455925166705	UP	0.558500910363044	0.646241622029922	Inflammatory bowel disease (IBD): IFNG*
hsa05205__109	0.579365234151638	DOWN	-0.555708405811228	0.647992425577933	Proteoglycans in cancer: SMAD2
hsa04540__10	0.581277500879291	DOWN	-0.552915901259413	0.649744452202372	Gap junction: C00533
hsa05161__92	0.587031943677358	DOWN	-0.544538387603967	0.655396923452023	Hepatitis B: NFKBIA
hsa05205__146	0.587031943677358	UP	0.544538387603967	0.655396923452023	Proteoglycans in cancer: PTK2
hsa05140__26	0.592812629736754	UP	0.536160873948522	0.661457797669454	Leishmaniasis: C00533
hsa04650__39	0.59474530731582	DOWN	-0.533368369396707	0.662827065507963	Natural killer cell mediated cytotoxicity: FAS
hsa05016__55	0.59474530731582	DOWN	-0.533368369396707	0.662827065507963	Huntington's disease: TGM2
hsa04921__77	0.600560535760375	UP	0.524990855741261	0.668514956572124	Oxytocin signaling pathway: KCNJ3
hsa04933__25	0.600560535760375	UP	0.524990855741261	0.668514956572124	AGE-RAGE signaling pathway in diabetic complications: IL1A
hsa04620__40	0.602504640793609	DOWN	-0.522198351189446	0.669885337308397	Toll-like receptor signaling pathway: CCL5
hsa04662__36	0.602504640793609	UP	0.522198351189446	0.669885337308397	B cell receptor signaling pathway: CD79A
hsa04650__119	0.606401328121301	DOWN	-0.516613342085815	0.673819098486058	Natural killer cell mediated cytotoxicity: KLRC4-KLRK1
hsa04722__73 77	0.610309244254603	DOWN	-0.511028332982185	0.676960489937662	Neurotrophin signaling pathway: NGFRAP1 YWHAE
hsa05150__1 2 3	0.610309244254603	DOWN	-0.511028332982185	0.676960489937662	Staphylococcus aureus infection: CFD C3 CFB
hsa05205__145	0.610309244254603	UP	0.511028332982185	0.676960489937662	Proteoglycans in cancer: PXN
hsa04913__64	0.614228299304728	DOWN	-0.505443323878554	0.680504112260368	Ovarian steroidogenesis: PLA2G4B
hsa04921__48	0.614228299304728	UP	0.505443323878554	0.680504112260368	Oxytocin signaling pathway: PRKAG2
hsa04010__118	0.618158402430799	UP	0.499858314774924	0.684454707228917	MAPK signaling pathway: JUN
hsa05200__5	0.620127568375632	DOWN	-0.497065810223109	0.685826781034616	Pathways in cancer: CASP3*
hsa05210__7	0.620127568375632	DOWN	-0.497065810223109	0.685826781034616	Colorectal cancer: CASP3*
hsa04810__26 80	0.628031390912465	UP	0.485895792015848	0.694159402073248	Regulation of actin cytoskeleton: PFN3 ACTB
hsa04210__3	0.635978103405718	UP	0.474725773808587	0.702116836838627	Apoptosis: BCL2L1
hsa04310__35	0.635978103405718	DOWN	-0.474725773808587	0.702116836838627	Wnt signaling pathway: JUN
hsa04010__62	0.63797139386723	DOWN	-0.471933269256772	0.703903845611582	MAPK signaling pathway: MEF2C
hsa04710__5	0.64396694178335	DOWN	-0.463555755601326	0.710102044372603	Circadian rhythm: RORA
hsa04066__26	0.645970642615316	DOWN	-0.460763251049511	0.711059658742928	HIF-1 signaling pathway: C01245
hsa04728__71 72	0.645970642615316	DOWN	-0.460763251049511	0.711059658742928	Dopaminergic synapse: CLOCK ARNTL
hsa05130__26	0.645970642615316	UP	0.460763251049511	0.711059658742928	Pathogenic Escherichia coli infection: CTNNB1
hsa04151__35	0.647976915411135	UP	0.457970746497696	0.712433366914876	PI3K-Akt signaling pathway: CCND1
hsa05164__77	0.647976915411135	UP	0.457970746497696	0.712433366914876	Influenza A: CASP9
hsa04742__8	0.651996995177811	DOWN	-0.452385737394065	0.716015547839968	Taste transduction: PLCB2
hsa04810__21 82	0.651997127383814	DOWN	-0.452385737394065	0.716015547839968	Regulation of actin cytoskeleton: CFL1 ACTB
hsa04971__49	0.654011041666337	UP	0.44959323284225	0.717807679492434	Gastric acid secretion: KCNJ1
hsa04913__45	0.656027478124483	DOWN	-0.446800728290435	0.719600485344952	Ovarian steroidogenesis: ACOT2
hsa05014__53	0.660067867171822	DOWN	-0.441215719186804	0.723188059717699	Amyotrophic lateral sclerosis (ALS): RAB5A
hsa05222__32	0.660067867171822	UP	0.441215719186804	0.723188059717699	Small cell lung cancer: BIRC8
hsa04071__69	0.668178353962439	UP	0.430045700979544	0.731647509962367	Sphingolipid signaling pathway: RAC1
hsa03320__28	0.674286809598041	DOWN	-0.421668187324098	0.737476667773411	PPAR signaling pathway: ACSL1
hsa04024__44 67	0.674286809598041	UP	0.421668187324098	0.737476667773411	cAMP signaling pathway: CREB3 CREBBP
hsa04062__42	0.676327766653368	DOWN	-0.418875682772283	0.738848763687022	Chemokine signaling pathway: PAK1
hsa04910__42	0.676327766653368	DOWN	-0.418875682772283	0.738848763687022	Insulin signaling pathway: PCK1
hsa04750__60	0.682464747522321	UP	0.410498169116837	0.745119849270448	Inflammatory mediator regulation of TRP channels: TRPV3
hsa04151__51	0.684515270465356	UP	0.407705664565022	0.746058116707891	PI3K-Akt signaling pathway: NOS3
hsa05014__49	0.684515270465356	DOWN	-0.407705664565022	0.746058116707891	Amyotrophic lateral sclerosis (ALS): C00001
hsa05145__11	0.684515270465356	UP	0.407705664565022	0.746058116707891	Toxoplasmosis: MAPK14
hsa04010__131	0.692740017190586	DOWN	-0.396535646357761	0.753710765663643	MAPK signaling pathway: MYC
hsa05164__35	0.692740017190586	DOWN	-0.396535646357761	0.753710765663643	Influenza A: IL18
hsa05205__236	0.692740017190586	UP	0.396535646357761	0.753710765663643	Proteoglycans in cancer: ITGAV
hsa05152__81	0.694801922419798	UP	0.393743141805946	0.755516673742361	Tuberculosis: IFNA1
hsa04621__30 32	0.698932500210201	DOWN	-0.388158132702315	0.7591295768179	NOD-like receptor signaling pathway: PYCARD CASP1
hsa05200__213	0.698932500210201	DOWN	-0.388158132702315	0.7591295768179	Pathways in cancer: CSF2RA
hsa04024__123	0.701001145448952	UP	0.3853656281505	0.760936540900394	cAMP signaling pathway: PAK1
hsa04012__40	0.705145079934798	DOWN	-0.37978061904687	0.764110498960488	ErbB signaling pathway: ELK1*
hsa04152__103	0.705145079934798	UP	0.37978061904687	0.764110498960488	AMPK signaling pathway: ULK1
hsa04540__11	0.705145079934798	DOWN	-0.37978061904687	0.764110498960488	Gap junction: C00780
hsa05212__19	0.709297780952084	DOWN	-0.374195609943239	0.768167452685283	Pancreatic cancer: MAPK8
hsa04917__68	0.711377384172045	DOWN	-0.371403105391424	0.769532587714031	Prolactin signaling pathway: CCND1
hsa05217__10	0.711377384172045	UP	0.371403105391424	0.769532587714031	Basal cell carcinoma: PTCH1*
hsa04115__37	0.713459137242416	DOWN	-0.368610600839609	0.770896905623059	p53 signaling pathway: FAS
hsa05140__21	0.713459137242416	DOWN	-0.368610600839609	0.770896905623059	Leishmaniasis: NFKB1
hsa04917__33	0.72180736675554	DOWN	-0.357440582632348	0.779468989731988	Prolactin signaling pathway: CSN2
hsa05223__14	0.72389965770902	DOWN	-0.354648078080533	0.781279412312032	Non-small cell lung cancer: CCND1
hsa03320__58	0.725994013635245	DOWN	-0.351855573528717	0.78308998370874	PPAR signaling pathway: CYP8B1
hsa05222__34	0.728090420224223	UP	0.349063068976902	0.784450630505341	Small cell lung cancer: CCND1
hsa05321__92	0.728090420224223	DOWN	-0.349063068976902	0.784450630505341	Inflammatory bowel disease (IBD): IL17F
hsa04370__36	0.730188863119953	UP	0.346270564425087	0.786260672666128	VEGF signaling pathway: NOS3
hsa05223__24	0.732289327920717	DOWN	-0.343478059873272	0.78807081739005	Non-small cell lung cancer: STK4
hsa04024__43	0.734391800179368	DOWN	-0.340685555321457	0.78988104896224	cAMP signaling pathway: MAPK8
hsa05200__214	0.736496265403632	DOWN	-0.337893050769641	0.791691351655277	Pathways in cancer: CSF3R
hsa04917__34	0.738602709056397	UP	0.335100546217826	0.793501709729542	Prolactin signaling pathway: ELF5
hsa05205__434	0.7512820983196	DOWN	-0.318345518906935	0.806662321567159	Proteoglycans in cancer: CASP3
hsa04370__39	0.753401980229656	DOWN	-0.31555301435512	0.808015023317079	VEGF signaling pathway: RAC1
hsa05161__44	0.753401980229656	DOWN	-0.31555301435512	0.808015023317079	Hepatitis B: CXCL8
hsa04742__49	0.757647310783757	UP	0.309968005251489	0.811179086588422	Taste transduction: HTR1A
hsa05161__57	0.757647310783757	DOWN	-0.309968005251489	0.811179086588422	Hepatitis B: STAT3*
hsa05211__27	0.757647310783757	DOWN	-0.309968005251489	0.811179086588422	Renal cell carcinoma: VEGFA*
hsa05030__80 81	0.7618999639278	DOWN	-0.304382996147859	0.815267672107253	Cocaine addiction: GRIN3A DLG4
hsa05134__69	0.76402899891978	UP	0.301590491596044	0.816615750267502	Legionellosis: IL1B*
hsa05205__142	0.76402899891978	UP	0.301590491596044	0.816615750267502	Proteoglycans in cancer: CTNNB1
hsa03320__42	0.766159819415676	DOWN	-0.298797987044228	0.817962670842076	PPAR signaling pathway: ACOX1
hsa04621__33 35	0.766159819415676	UP	0.298797987044228	0.817962670842076	NOD-like receptor signaling pathway: NLRC4 PYCARD
hsa04910__24	0.768292410282716	UP	0.296005482492413	0.819308421635201	Insulin signaling pathway: ACACA
hsa04933__29	0.768292410282716	DOWN	-0.296005482492413	0.819308421635201	AGE-RAGE signaling pathway in diabetic complications: ICAM1
hsa05321__94	0.770426756347939	DOWN	-0.293212977940598	0.821118477128632	Inflammatory bowel disease (IBD): IL22
hsa04919__44	0.774700653182033	DOWN	-0.287627968836967	0.824737975823819	Thyroid hormone signaling pathway: PFKFB2
hsa05200__200	0.774700653182033	DOWN	-0.287627968836967	0.824737975823819	Pathways in cancer: FIGF
hsa04024__34	0.776840173406905	DOWN	-0.284835464285152	0.826547387220597	cAMP signaling pathway: ATP2B1
hsa04115__34	0.781124280820072	DOWN	-0.279250455181522	0.830635270889029	p53 signaling pathway: ZMAT3
hsa05134__6	0.787562878240511	UP	0.270872941526076	0.837008285188869	Legionellosis: IL1B
hsa04724__65	0.789712227430957	UP	0.268080436974261	0.838344334190198	Glutamatergic synapse: GRM3
hsa05231__21	0.789712331834301	DOWN	-0.268080436974261	0.838344334190198	Choline metabolism in cancer: PCYT1A
hsa04972__42	0.791863386757445	DOWN	-0.265287932422446	0.840153192386922	Pancreatic secretion: CFTR
hsa05120__18	0.798326003386752	DOWN	-0.256910418767	0.846531918941143	Epithelial cell signaling in Helicobacter pylori infection: CCL5
hsa05145__29	0.800483267612612	UP	0.254117914215185	0.848340699291651	Toxoplasmosis: C06314
hsa04610__23	0.802642134278409	DOWN	-0.25132540966337	0.850149137716534	Complement and coagulation cascades: BDKRB1
hsa04024__116	0.804802468456952	DOWN	-0.248532905111554	0.850519594055463	cAMP signaling pathway: ACOX1
hsa04210__59	0.804802468456952	DOWN	-0.248532905111554	0.850519594055463	Apoptosis: PMAIP1
hsa04917__45	0.804802468456952	UP	0.248532905111554	0.850519594055463	Prolactin signaling pathway: SLC2A2
hsa05212__14	0.804802468456952	DOWN	-0.248532905111554	0.850519594055463	Pancreatic cancer: MAPK1
hsa04330__12	0.806964294061025	DOWN	-0.245740400559739	0.851846016034082	Notch signaling pathway: HES1
hsa04370__23	0.806964294061025	DOWN	-0.245740400559739	0.851846016034082	VEGF signaling pathway: PTK2
hsa05219__12	0.81129231849864	DOWN	-0.240155391456109	0.855453612350901	Bladder cancer: ERBB2
hsa05152__9	0.811292356151839	UP	0.240155391456109	0.855453612350901	Tuberculosis: TCIRG1
hsa04064__136	0.813458560857386	UP	0.237362886904293	0.856776141172102	NF-kappa B signaling pathway: TNFSF13B*
hsa04621__23	0.813458560857386	UP	0.237362886904293	0.856776141172102	NOD-like receptor signaling pathway: CASP1
hsa04668__138	0.819965678231604	DOWN	-0.228985373248848	0.862662659236945	TNF signaling pathway: NFKB1*
hsa05200__202	0.819965678231604	DOWN	-0.228985373248848	0.862662659236945	Pathways in cancer: FIGF*
hsa05134__7	0.828661077230934	UP	0.217815355041587	0.871322979360338	Legionellosis: IL18
hsa04650__15	0.830838255804643	DOWN	-0.215022850489772	0.873123648018414	Natural killer cell mediated cytotoxicity: TNF
hsa04931__140	0.833016733567937	DOWN	-0.212230345937957	0.874923668180075	Insulin resistance: G00369
hsa04961__26	0.839559799620434	DOWN	-0.203852832282511	0.88081120239352	Endocrine and other factor-regulated calcium reabsorption: TRPV5*
hsa05164__34	0.839559799620434	DOWN	-0.203852832282511	0.88081120239352	Influenza A: IL1B
hsa05223__37	0.841743311620781	UP	0.201060327730696	0.882609197843441	Non-small cell lung cancer: CCND1*
hsa04064__95	0.843928041404951	UP	0.19826782317888	0.883913483723469	NF-kappa B signaling pathway: BCL2L1**
hsa05212__29	0.843928041404951	UP	0.19826782317888	0.883913483723469	Pancreatic cancer: VEGFA
hsa04064__36	0.846113972606	UP	0.195475318627065	0.884723513926919	NF-kappa B signaling pathway: PLCG1
hsa04115__24	0.846113972606	UP	0.195475318627065	0.884723513926919	p53 signaling pathway: SERPINB5
hsa04720__32	0.846113972606	DOWN	-0.195475318627065	0.884723513926919	Long-term potentiation: ITPR1
hsa04110__96 97	0.852678810627027	DOWN	-0.18709780497162	0.890596712155744	Cell cycle: TFDP1 E2F4
hsa05200__196	0.852678810627027	DOWN	-0.18709780497162	0.890596712155744	Pathways in cancer: TRAF1
hsa04210__61	0.857061075099977	DOWN	-0.181512795867989	0.894676533396032	Apoptosis: APAF1
hsa04350__12	0.859253869568684	UP	0.178720291316174	0.896467529661053	TGF-beta signaling pathway: ACVR2A
hsa04620__12	0.863642700204077	DOWN	-0.173135282212543	0.900546411589046	Toll-like receptor signaling pathway: NFKB1
hsa04742__27	0.868035742456563	DOWN	-0.167550273108913	0.904123702924547	Taste transduction: CALHM1
hsa04921__23	0.868035742456563	UP	0.167550273108913	0.904123702924547	Oxytocin signaling pathway: C00219
hsa04919__25	0.870233801355176	DOWN	-0.164757768557098	0.90591097659079	Thyroid hormone signaling pathway: MTOR
hsa04210__73	0.872432863209492	UP	0.161965264005283	0.907697314490939	Apoptosis: TRAF1
hsa04931__67	0.874632886036268	DOWN	-0.159172759453467	0.908979668347372	Insulin resistance: IKBKB**
hsa04350__27	0.874632911320941	UP	0.159172759453467	0.908979668347372	TGF-beta signaling pathway: ACVR2A*
hsa04912__33	0.876833928968079	DOWN	-0.156380254901652	0.910763378955788	GnRH signaling pathway: ELK1
hsa04064__54	0.88564735970538	UP	0.145210236694391	0.918394806228702	NF-kappa B signaling pathway: CCL13
hsa05100__15	0.88564735970538	UP	0.145210236694391	0.918394806228702	Bacterial invasion of epithelial cells: CTNNA1
hsa05162__25 70	0.88564735970538	UP	0.145210236694391	0.918394806228702	Measles: IFNAR1 GNB2L1
hsa05150__14	0.887852950779193	DOWN	-0.142417732142576	0.919666889242082	Staphylococcus aureus infection: FPR1
hsa04062__8 41	0.887852973435411	DOWN	-0.142417732142576	0.919666889242082	Chemokine signaling pathway: PXN PTK2B
hsa04917__47	0.890059455913502	UP	0.139625227590761	0.920937069196845	Prolactin signaling pathway: INS
hsa05169__118	0.890059455913502	UP	0.139625227590761	0.920937069196845	Epstein-Barr virus infection: MDM2
hsa05216__15	0.892266790268806	DOWN	-0.136832723038946	0.922712877773851	Thyroid cancer: CCND1
hsa04730__8	0.896683947029047	DOWN	-0.131247713935315	0.926770702127382	Long-term depression: GNA13*
hsa05205__238	0.901104308360303	DOWN	-0.125662704831685	0.930827375156135	Proteoglycans in cancer: ITGAV*
hsa04014__43	0.903315648359489	UP	0.12287020027987	0.932598957839275	Ras signaling pathway: ELK1
hsa04062__22 41	0.91216834075717	DOWN	-0.111700182072609	0.941221478463879	Chemokine signaling pathway: CRK PTK2B
hsa04713__14	0.921031947138432	UP	0.100530163865348	0.949845789612027	Circadian entrainment: PRKCA
hsa04024__60	0.927686156418533	DOWN	-0.0921526502099022	0.955659149073697	cAMP signaling pathway: PDE3A
hsa04115__18	0.927686156418533	UP	0.0921526502099022	0.955659149073697	p53 signaling pathway: CCNG1
hsa04742__48	0.934345426874402	UP	0.0837751365544565	0.961464981980833	Taste transduction: GABBR1
hsa04921__59	0.934345426874402	UP	0.0837751365544565	0.961464981980833	Oxytocin signaling pathway: CCND1
hsa04151__36	0.936566228255445	DOWN	-0.0809826320026413	0.962695811210055	PI3K-Akt signaling pathway: PCK1
hsa04923__52 53	0.936566228255445	UP	0.0809826320026413	0.962695811210055	Regulation of lipolysis in adipocytes: PNPLA2 ABHD5*
hsa04921__33	0.938787523253748	DOWN	-0.0781901274508261	0.964451479602948	Oxytocin signaling pathway: C00942
hsa04917__71	0.941009294653415	UP	0.0753976228990109	0.966205718390037	Prolactin signaling pathway: CCND1*
hsa04620__34	0.945454197738051	DOWN	-0.0698126137953804	0.970239452512178	Toll-like receptor signaling pathway: IL1B
hsa04014__79	0.947677294937217	UP	0.0670201092435652	0.971989976630476	Ras signaling pathway: RAC1**
hsa04530__20 37	0.956573585319353	UP	0.0558500910363044	0.980579250853827	Tight junction: ACTB TJP3
hsa04340__46	0.958798546907205	DOWN	-0.0530575864844891	0.981254068430631	Hedgehog signaling pathway: PRKACA
hsa04530__4 37 11	0.958798546907205	DOWN	-0.0530575864844891	0.981254068430631	Tight junction: OCLN TJP3 TJP1
hsa05134__72	0.958798546907205	DOWN	-0.0530575864844891	0.981254068430631	Legionellosis: IL12A
hsa05162__20	0.963249415791685	DOWN	-0.0474725773808587	0.985272537981805	Measles: NFKB1
hsa05164__65 66	0.96547528846312	UP	0.0446800728290435	0.987012005996846	Influenza A: DNAJC3 HSPA1A
hsa04917__38	0.967701430192463	DOWN	-0.0418875682772283	0.988749857167829	Prolactin signaling pathway: IRF1
hsa04919__89	0.972154451502457	UP	0.0363025591735978	0.991681983915916	Thyroid hormone signaling pathway: CASP9
hsa05211__3	0.972154451502457	UP	0.0363025591735978	0.991681983915916	Renal cell carcinoma: VEGFA
hsa05321__83	0.972154451502457	UP	0.0363025591735978	0.991681983915916	Inflammatory bowel disease (IBD): IL2
hsa04360__18	0.976608341020418	UP	0.0307175500699674	0.995144833393365	Axon guidance: PTK2
hsa05200__198	0.976608341020418	DOWN	-0.0307175500699674	0.995144833393365	Pathways in cancer: BCL2L1*
hsa04920__12	0.978835561535977	DOWN	-0.0279250455181522	0.995794278426906	Adipocytokine signaling pathway: C00165
hsa04923__26 27	0.978835565839116	DOWN	-0.0279250455181522	0.995794278426906	Regulation of lipolysis in adipocytes: PNPLA2 ABHD5
hsa04152__89	0.978835567990684	UP	0.0279250455181522	0.995794278426906	AMPK signaling pathway: CFTR
hsa04064__130	0.98329049958165	DOWN	-0.0223400364145217	0.999244374642467	NF-kappa B signaling pathway: TNF*
hsa04662__6	0.98329049958165	UP	0.0223400364145217	0.999244374642467	B cell receptor signaling pathway: NFKB1
hsa04015__3	0.985518169482161	DOWN	-0.0195475318627065	1	Rap1 signaling pathway: MAPK1
hsa05100__24	0.985518169482161	UP	0.0195475318627065	1	Bacterial invasion of epithelial cells: ACTB
hsa04921__80	0.987745952300546	UP	0.0167550273108913	1	Oxytocin signaling pathway: KCNJ2
hsa04330__11	0.989973830669296	UP	0.0139625227590761	1	Notch signaling pathway: PTCRA
hsa05222__35	0.989973830669296	DOWN	-0.0139625227590761	1	Small cell lung cancer: NOS2
hsa04152__81	0.994429804577081	DOWN	-0.00837751365544565	1	AMPK signaling pathway: LIPE
hsa04010__88 92	0.996657865371545	DOWN	-0.00558500910363044	1	MAPK signaling pathway: ECSIT TRAF6
hsa04550__22	0.998885952228044	DOWN	-0.00279250455181522	1	Signaling pathways regulating pluripotency of stem cells: SMAD2
hsa05132__6	0.998885952228044	UP	0.00279250455181522	1	Salmonella infection: NFKB1
hsa04152__33	1	0	0	1	AMPK signaling pathway: CPT1C
hsa04152__41	1	0	0	1	AMPK signaling pathway: FBP1
hsa04211__2	1	0	0	1	Longevity regulating pathway - mammal: RPS6KB1
hsa04911__41	1	0	0	1	Insulin secretion: ABCC8
hsa04911__35	1	0	0	1	Insulin secretion: TRPM4
hsa04922__67	1	0	0	1	Glucagon signaling pathway: FBP1
hsa04922__60	1	0	0	1	Glucagon signaling pathway: CPT1C*
hsa04924__34	1	0	0	1	Renin secretion: REN
hsa04924__47	1	0	0	1	Renin secretion: KCNMA1
hsa04931__151	1	0	0	1	Insulin resistance: CPT1A
hsa04931__29	1	0	0	1	Insulin resistance: CPT1B
hsa04960__15	1	0	0	1	Aldosterone-regulated sodium reabsorption: C00762
hsa05030__13	1	0	0	1	Cocaine addiction: SLC6A3
hsa05031__15	1	0	0	1	Amphetamine addiction: MAOA
hsa05031__77	1	0	0	1	Amphetamine addiction: MAOA*
hsa05034__7	1	0	0	1	Alcoholism: GRIN3A
hsa05034__75	1	0	0	1	Alcoholism: SLC29A1
hsa05140__37	1	0	0	1	Leishmaniasis: ELK1
hsa05140__55	1	0	0	1	Leishmaniasis: JUN
hsa05140__41 57	1	0	0	1	Leishmaniasis: NOS2 CYBA
hsa05211__12	1	0	0	1	Renal cell carcinoma: EGLN2