p.value	UP.DOWN	statistic	FDRp.value	path.name
hsa04211__43 59 60 61	5.72498756941136e-27	UP	10.7536289397044	5.38385391024436e-24	Longevity regulating pathway - mammal: ULK3 RB1CC1 ATG13 ATG101
hsa04530__11 24 23	5.73055232596526e-27	DOWN	-10.7536289397044	5.38385391024436e-24	Tight junction: TJP1 YBX3 CDK4
hsa05215__22	1.15451853372213e-26	DOWN	-6.16946787284829	7.07904097907041e-24	Prostate cancer: C16038
hsa04750__8	1.50698051709854e-26	DOWN	-10.6640153652069	7.07904097907041e-24	Inflammatory mediator regulation of TRP channels: ASIC2
hsa03320__7	1.73222364760311e-25	DOWN	-10.4346472876239	6.50969646769248e-23	PPAR signaling pathway: AQP7
hsa03320__53	2.96606241798781e-25	DOWN	-10.3834395307682	9.28871880566516e-23	PPAR signaling pathway: ADIPOQ
hsa03320__10	4.48185991381377e-25	DOWN	-10.3439668848586	1.20305925400801e-22	PPAR signaling pathway: PLIN1
hsa03320__38	3.56470676567822e-24	DOWN	-10.1434031705069	8.37260501588672e-22	PPAR signaling pathway: SORBS1
hsa04960__3	1.79256155212395e-23	DOWN	-9.98444575860059	3.74247017382323e-21	Aldosterone-regulated sodium reabsorption: SCNN1A
hsa04152__27	3.67577060002141e-23	DOWN	-9.91296826465612	6.90677295744024e-21	AMPK signaling pathway: ADIPOR1
hsa04930__3	7.42026334630411e-23	DOWN	-9.84255759897948	1.26751589342777e-20	Type II diabetes mellitus: SLC2A4
hsa04211__50	4.11829488589122e-22	DOWN	-9.66866459132355	6.44856340882466e-20	Longevity regulating pathway - mammal: PPARGC1A*
hsa05210__21	8.97054011024304e-22	UP	9.58865247123646	1.29658806670359e-19	Colorectal cancer: BIRC5
hsa04622__21 22 23	1.68181491529857e-21	UP	9.52357594689897	2.2572358756043e-19	RIG-I-like receptor signaling pathway: CHUK IKBKB IKBKG
hsa03320__37	1.80711174480396e-21	DOWN	-9.51610814902417	2.26370864565775e-19	PPAR signaling pathway: HMGCS2
hsa05161__100	2.0437446429889e-21	UP	9.50330620981024	2.40012261511009e-19	Hepatitis B: MMP9*
hsa05200__189	2.92345034372924e-21	UP	9.46596722043626	3.2312724681572e-19	Pathways in cancer: BIRC5
hsa04920__2	3.33801882152265e-21	DOWN	-9.4520984529545	3.48452075868948e-19	Adipocytokine signaling pathway: C00638
hsa04932__35	4.86356910735513e-21	DOWN	-9.41262580704487	4.80718201741341e-19	Non-alcoholic fatty liver disease (NAFLD): PRKAG2
hsa03320__28	5.11674509570347e-21	DOWN	-9.40729166570573	4.80718201741341e-19	PPAR signaling pathway: ACSL1
hsa03320__36	6.14089735387005e-21	DOWN	-9.38808875688483	5.49464101329611e-19	PPAR signaling pathway: SLC27A4
hsa04530__11 62	8.06848217976972e-21	DOWN	-9.35928439365348	6.89121727990332e-19	Tight junction: TJP1 SHROOM1
hsa04920__28	1.58291108299599e-20	DOWN	-9.28780689970902	1.29316953258672e-18	Adipocytokine signaling pathway: SLC2A1
hsa05166__64	1.83940671613605e-20	UP	9.2718044756916	1.44010217484151e-18	HTLV-I infection: CCNB2
hsa04666__42	2.07384151840651e-20	UP	9.25900253647767	1.55869928523433e-18	Fc gamma R-mediated phagocytosis: MYO10
hsa04610__11	2.53191303690876e-20	UP	9.23766597112111	1.82979407551983e-18	Complement and coagulation cascades: F2R
hsa03320__21	2.91074184945177e-20	DOWN	-9.22273037537152	2.02566071671106e-18	PPAR signaling pathway: ACAA1
hsa04914__11	3.27968123345874e-20	UP	9.20992843615759	2.20090037059606e-18	Progesterone-mediated oocyte maturation: CDK1
hsa03320__60	4.1617534898897e-20	DOWN	-9.18432455772972	2.69652924396646e-18	PPAR signaling pathway: CYP27A1
hsa04610__57	4.50500583374498e-20	UP	9.1757899315871	2.82163532053561e-18	Complement and coagulation cascades: PLAUR
hsa04923__26 27	5.12331391023989e-20	DOWN	-9.16192116410534	3.10538930236799e-18	Regulation of lipolysis in adipocytes: PNPLA2 ABHD5
hsa04510__6 4 5	5.59915743098655e-20	UP	9.15231970969488	3.28775525400742e-18	Focal adhesion: FLNA ITGB1 ITGA11
hsa04510__26 4 5	6.68788342469545e-20	UP	9.13311680087398	3.80804028939477e-18	Focal adhesion: ACTN4 ITGB1 ITGA11
hsa03320__23	7.90724731625655e-20	DOWN	-9.11498072032091	4.2450622020703e-18	PPAR signaling pathway: ACADL
hsa04742__49	7.90724731625655e-20	UP	9.11498072032091	4.2450622020703e-18	Taste transduction: HTR1A
hsa04114__80	8.22454077938419e-20	UP	9.1107134072496	4.29275336790636e-18	Oocyte meiosis: CDC25C*
hsa03320__8	1.45206097556573e-19	DOWN	-9.04883736771558	7.18005940286318e-18	PPAR signaling pathway: GK
hsa04650__14	1.45206097556573e-19	UP	9.04883736771558	7.18005940286318e-18	Natural killer cell mediated cytotoxicity: CSF2
hsa04510__20 4 5	1.64850955782993e-19	UP	9.03496860023382	7.94243451067294e-18	Focal adhesion: VASP ITGB1 ITGA11
hsa04152__89	2.04251273094342e-19	DOWN	-9.01149837834161	9.5947035536067e-18	AMPK signaling pathway: CFTR
hsa04976__16	2.22931498071581e-19	DOWN	-9.00189692393116	1.02167874360122e-17	Bile secretion: CFTR
hsa04110__59 15 16 17 18 19 20	2.78688964732731e-19	UP	8.97735987377112	1.24680134460191e-17	Cell cycle: CDC45 MCM7 MCM6 MCM5 MCM4 MCM3 MCM2
hsa05205__369	2.86910309138946e-19	UP	8.97415938896764	1.25373132760949e-17	Proteoglycans in cancer: HOXD10
hsa04914__30	3.22252130144369e-19	UP	8.9613574497537	1.37616307395743e-17	Progesterone-mediated oocyte maturation: CDK1*
hsa04115__43 57	5.58392289519448e-19	UP	8.90054823848752	2.33159802668232e-17	p53 signaling pathway: CDK1 CCNB3
hsa04066__50	1.00153522112952e-18	DOWN	-8.83547171415002	4.09105365326604e-17	HIF-1 signaling pathway: TF
hsa04972__42	1.33285601620342e-18	DOWN	-8.80346686611519	5.32858820094943e-17	Pancreatic secretion: CFTR
hsa04923__52 53	1.45188638513807e-18	DOWN	-8.79386541170474	5.68353024515508e-17	Regulation of lipolysis in adipocytes: PNPLA2 ABHD5*
hsa04390__18	1.61169824592195e-18	UP	8.78213030075863	6.18036939609661e-17	Hippo signaling pathway: MOB1A
hsa04012__21	2.00409280972368e-18	UP	8.75759325059859	7.53138077894157e-17	ErbB signaling pathway: GSK3B
hsa04152__54	3.06425164338279e-18	DOWN	-8.70958597854634	1.12896643880711e-16	AMPK signaling pathway: SLC2A4*
hsa04210__74	3.24218111860103e-18	UP	8.70318500893937	1.1715496772791e-16	Apoptosis: BAX*
hsa03320__9	4.25665306093233e-18	DOWN	-8.67224698917236	1.50910398141356e-16	PPAR signaling pathway: PCK1
hsa05321__152	6.60407670084697e-18	UP	8.62210606058446	2.29797409646138e-16	Inflammatory bowel disease (IBD): FOXP3*
hsa04152__44	7.59382923009855e-18	DOWN	-8.60610363656704	2.5943282042464e-16	AMPK signaling pathway: SLC2A4
hsa04622__5 33	9.14439446197608e-18	UP	8.58476707121048	3.06827092750947e-16	RIG-I-like receptor signaling pathway: MAVS TMEM173
hsa04622__45	9.49009040376251e-18	UP	8.58049975813917	3.12839997695961e-16	RIG-I-like receptor signaling pathway: MAPK14
hsa04152__78	1.02206312133834e-17	UP	8.57196513199655	3.31113207757715e-16	AMPK signaling pathway: CCNA2
hsa05110__17	1.14216857077346e-17	DOWN	-8.55916319278261	3.63751651607343e-16	Vibrio cholerae infection: C00698*
hsa05211__2	1.21855471812888e-17	UP	8.55169539490782	3.8161071922736e-16	Renal cell carcinoma: TGFB1
hsa04914__29	1.50676386632105e-17	UP	8.52715834474778	4.64132672920861e-16	Progesterone-mediated oocyte maturation: CDK2
hsa04530__11 36 14	1.57784824579191e-17	DOWN	-8.52182420340864	4.78189815135969e-16	Tight junction: TJP1 CTNNB1 CTNNA1
hsa04360__6	2.04128127403064e-17	UP	8.49195301190946	6.08820240302154e-16	Axon guidance: MAPK1
hsa04115__31	2.52048020578862e-17	DOWN	-8.46741596174942	7.39997235418253e-16	p53 signaling pathway: ADGRB1
hsa04150__56	2.614471889956e-17	DOWN	-8.46314864867811	7.5578348941959e-16	mTOR signaling pathway: EIF4B
hsa04950__31	2.73683651863285e-17	UP	8.45781450733897	7.79169063410775e-16	Maturity onset diabetes of the young: NKX6-1*
hsa04210__75	2.91769032959316e-17	UP	8.45034670946418	8.18259720791874e-16	Apoptosis: BAK1*
hsa05161__207	3.11032398665653e-17	UP	8.44287891158938	8.46999821873569e-16	Hepatitis B: CDK2
hsa05161__219	3.11032398665653e-17	UP	8.44287891158938	8.46999821873569e-16	Hepatitis B: CDK2*
hsa04922__17	3.19667299133305e-17	DOWN	-8.4396784267859	8.58078364387828e-16	Glucagon signaling pathway: PKM
hsa05120__20	3.34587278602883e-17	UP	8.43434428544676	8.85478164077209e-16	Epithelial cell signaling in Helicobacter pylori infection: CXCL8
hsa04211__52	3.9063964809938e-17	DOWN	-8.41620820489369	1.01946097052602e-15	Longevity regulating pathway - mammal: PPARG
hsa04071__65	4.5181178169815e-17	UP	8.39913895260844	1.16295114768606e-15	Sphingolipid signaling pathway: BAX*
hsa04933__59	4.72798485081732e-17	UP	8.3938048112693	1.20052480198456e-15	AGE-RAGE signaling pathway in diabetic complications: SERPINE1
hsa04810__23	5.08393922622766e-17	DOWN	-8.38527018512668	1.2736962408109e-15	Regulation of actin cytoskeleton: GSN
hsa04010__13	6.26121683843604e-17	UP	8.36073313496664	1.54800347887123e-15	MAPK signaling pathway: STMN1
hsa05031__11	6.49178757011087e-17	UP	8.35646582189533	1.55807786708136e-15	Amphetamine addiction: GRIN3A
hsa05031__54	6.49178757011087e-17	UP	8.35646582189533	1.55807786708136e-15	Amphetamine addiction: GRIN3A*
hsa04922__50	6.5507265300387e-17	DOWN	-8.3553989936275	1.55807786708136e-15	Glucagon signaling pathway: PCK1
hsa04960__4	8.13473390723425e-17	DOWN	-8.32979511519963	1.91064562646165e-15	Aldosterone-regulated sodium reabsorption: ATP1B4
hsa04012__37 7	1.02784139130923e-16	DOWN	-8.30205758023611	2.38433823983956e-15	ErbB signaling pathway: ERBB3 ERBB3
hsa04211__42	1.08472729122179e-16	DOWN	-8.29565661062914	2.48561290268994e-15	Longevity regulating pathway - mammal: PPARGC1A
hsa04960__13	1.10437055886467e-16	DOWN	-8.29352295409349	2.50013527723701e-15	Aldosterone-regulated sodium reabsorption: FXYD4
hsa05166__5	1.18651252783485e-16	UP	8.28498832795086	2.65411552357342e-15	HTLV-I infection: SLC2A1
hsa04923__16	1.28613696271367e-16	DOWN	-8.27538687354041	2.84311923875175e-15	Regulation of lipolysis in adipocytes: PLIN1
hsa04530__20 62	1.40652135498672e-16	DOWN	-8.26471859086214	3.07308561165121e-15	Tight junction: ACTB SHROOM1
hsa05205__146	1.49733402970186e-16	UP	8.25725079298734	3.23389728943654e-15	Proteoglycans in cancer: PTK2
hsa04724__5 71	1.62262993917679e-16	UP	8.24764933857689	3.46468369967408e-15	Glutamatergic synapse: GRIN3A DLG4
hsa05222__40	1.65184712777754e-16	UP	8.24551568204124	3.48743904842021e-15	Small cell lung cancer: TRAF1
hsa04115__11 12	1.854811173407e-16	UP	8.23164691455947	3.87243354981305e-15	p53 signaling pathway: CDK2 CCNE1
hsa04530__11 33	2.0456067215636e-16	DOWN	-8.21991180361337	4.2238406921077e-15	Tight junction: TJP1 CGN
hsa04916__6	2.21599792365942e-16	DOWN	-8.21031034920292	4.52593488973483e-15	Melanogenesis: DCT
hsa05321__95	2.33728792258591e-16	UP	8.20390937959595	4.72232688875153e-15	Inflammatory bowel disease (IBD): SMAD2
hsa03460__27	2.6229794173802e-16	UP	8.19004061211419	5.23416197236211e-15	Fanconi anemia pathway: BRCA1
hsa04950__20	2.64632989555296e-16	UP	8.18897378384636	5.23416197236211e-15	Maturity onset diabetes of the young: NKX6-1
hsa04530__4 37 11	2.99557502937638e-16	DOWN	-8.17403818809677	5.85432779340507e-15	Tight junction: OCLN TJP3 TJP1
hsa04530__6 11 45	3.02219156977271e-16	DOWN	-8.17297135982894	5.85432779340507e-15	Tight junction: CLDN24 TJP1 TJP2
hsa05161__213	3.07612588023519e-16	UP	8.17083770329329	5.89800053975706e-15	Hepatitis B: E2F1
hsa03320__31	3.15881082880308e-16	DOWN	-8.1676372184898	5.93540554732099e-15	PPAR signaling pathway: CD36
hsa04920__40	3.15881082880308e-16	DOWN	-8.1676372184898	5.93540554732099e-15	Adipocytokine signaling pathway: PPARGC1A
hsa05166__136 139	3.70295621307635e-16	UP	8.1484343096689	6.88896507363413e-15	HTLV-I infection: TP53 TBPL2
hsa04530__11 13	4.69666842273576e-16	DOWN	-8.11962994643755	8.65199996698087e-15	Tight junction: TJP1 EPB41
hsa04064__93	5.12787298506086e-16	UP	8.10896166375927	9.35463430964015e-15	NF-kappa B signaling pathway: PLAU
hsa04370__15	6.66940234763836e-16	UP	8.07695681572444	1.20498144338581e-14	VEGF signaling pathway: PLA2G4B
hsa05012__71	7.34229617629953e-16	DOWN	-8.06522170477833	1.31392138240636e-14	Parkinson's disease: PRKACA*
hsa04530__14 20 43	8.22414687511335e-16	DOWN	-8.05135293729657	1.45784641305075e-14	Tight junction: CTNNA1 ACTB ACTN4
hsa04360__114	8.36877419177821e-16	DOWN	-8.04921928076092	1.46961931835059e-14	Axon guidance: RAF1
hsa05205__91	8.74139615022668e-16	UP	8.04388513942178	1.52084105243296e-14	Proteoglycans in cancer: RAC1*
hsa04114__59	1.21609291540543e-15	UP	8.00334566524432	2.09636567710716e-14	Oocyte meiosis: REC8*
hsa04012__23	1.24812113683455e-15	DOWN	-8.00014518044084	2.1320178328292e-14	ErbB signaling pathway: RPS6KB1
hsa05168__79	1.39678420308272e-15	UP	7.98627641295908	2.36313864064442e-14	Herpes simplex infection: EIF2S1
hsa05200__188	1.42115115454544e-15	DOWN	-7.98414275642342	2.36313864064442e-14	Pathways in cancer: KLK3
hsa04961__17	1.42115309416082e-15	UP	7.98414275642342	2.36313864064442e-14	Endocrine and other factor-regulated calcium reabsorption: CALB1
hsa04530__5 10	1.49680016892903e-15	DOWN	-7.97774178681645	2.46709431352426e-14	Tight junction: IGSF5 MAGI1
hsa05211__40	1.59007805052371e-15	UP	7.97027398894166	2.5979808453511e-14	Renal cell carcinoma: PAK4
hsa04152__94	1.6038625761614e-15	DOWN	-7.96920716067383	2.5979808453511e-14	AMPK signaling pathway: MLYCD
hsa04910__48	1.63178567003009e-15	DOWN	-7.96707350413817	2.62061989229618e-14	Insulin signaling pathway: PPARGC1A
hsa04916__8	1.82532148567299e-15	DOWN	-7.95320473665641	2.90659243354199e-14	Melanogenesis: TYR*
hsa04068__96	1.95547858084847e-15	DOWN	-7.94467011051379	3.08768424656661e-14	FoxO signaling pathway: CCNG2
hsa03460__7	2.22462708553159e-15	UP	7.92866768649637	3.48339524476154e-14	Fanconi anemia pathway: FANCI
hsa05205__352	2.25688975993736e-15	UP	7.92546720169289	3.50470732142338e-14	Proteoglycans in cancer: ITGA5*
hsa05205__238	2.28267623016983e-15	UP	7.92546720169289	3.51569560367961e-14	Proteoglycans in cancer: ITGAV*
hsa04530__20 37	2.4239990198587e-15	DOWN	-7.91799940381809	3.7030033807435e-14	Tight junction: ACTB TJP3
hsa05200__204	2.46593508038974e-15	UP	7.91586574728244	3.73668710971962e-14	Pathways in cancer: TGFB1*
hsa04510__20 69	2.48717021307285e-15	UP	7.91479891901461	3.7387142642911e-14	Focal adhesion: VASP ACTB
hsa05169__104	2.70967627756401e-15	UP	7.90413063633633	4.04085851233554e-14	Epstein-Barr virus infection: IRF3
hsa03320__42	2.75647428267991e-15	DOWN	-7.90199697980068	4.07827966705162e-14	PPAR signaling pathway: ACOX1
hsa05215__12	3.56178918863843e-15	DOWN	-7.86999213176584	5.22859522300907e-14	Prostate cancer: KLK3
hsa04014__42	3.62304375046085e-15	DOWN	-7.86785847523019	5.27728620706662e-14	Ras signaling pathway: PLA2G4B
hsa03460__48	4.2591939379537e-15	UP	7.84758873814146	6.15617339185769e-14	Fanconi anemia pathway: RAD51
hsa04360__21	4.59773772226085e-15	UP	7.83798728373101	6.59477036651003e-14	Axon guidance: PAK4
hsa05010__37	5.00501595159503e-15	DOWN	-7.82731900105273	7.1245643735205e-14	Alzheimer's disease: MAPT
hsa05222__32	5.04764629874958e-15	UP	7.8262521727849	7.13122360552666e-14	Small cell lung cancer: BIRC8
hsa05205__145	5.58791109240836e-15	UP	7.81345023357097	7.83558577808606e-14	Proteoglycans in cancer: PXN
hsa04610__58	5.87905796148726e-15	UP	7.807049263964	8.18277771084041e-14	Complement and coagulation cascades: F2RL2
hsa04530__22 33	5.92900668762206e-15	DOWN	-7.80598243569617	8.19162026914841e-14	Tight junction: MYL12B CGN
hsa04015__92	5.97923261115314e-15	UP	7.80491560742835	8.200713924348e-14	Rap1 signaling pathway: C00076*
hsa04115__52 53	6.45204140146758e-15	UP	7.79531415301789	8.7850621690997e-14	p53 signaling pathway: CDK4 CCND1
hsa04510__23 4 5	8.45003768383842e-15	UP	7.7611756484474	1.14227487826852e-13	Focal adhesion: TLN1 ITGB1 ITGA11
hsa04922__59	9.19114007491357e-15	DOWN	-7.75050736576913	1.23358230005447e-13	Glucagon signaling pathway: CPT1C
hsa04520__43	1.08703826623248e-14	DOWN	-7.72917080041257	1.43841190299354e-13	Adherens junction: ACTB
hsa04670__35	1.08703826623248e-14	UP	7.72917080041257	1.43841190299354e-13	Leukocyte transendothelial migration: PTK2
hsa04720__32	1.16235957135801e-14	UP	7.72063617426995	1.5273242199872e-13	Long-term potentiation: ITPR1
hsa04520__44 52 45	1.29584934148938e-14	DOWN	-7.70676740678819	1.69090341156844e-13	Adherens junction: ACTB ACTN4 CTNNA1
hsa04152__63	1.30672124743229e-14	DOWN	-7.70570057852036	1.69333049925881e-13	AMPK signaling pathway: PPARG
hsa04024__92	1.60966608438752e-14	UP	7.67902987182466	2.07161820038641e-13	cAMP signaling pathway: GRIN3A
hsa04390__90	1.70622414418668e-14	UP	7.67156207394987	2.18094909314747e-13	Hippo signaling pathway: BBC3
hsa04910__18	1.82356606588277e-14	DOWN	-7.66302744780725	2.31518962013089e-13	Insulin signaling pathway: LIPE
hsa04922__51	2.31937024720549e-14	DOWN	-7.63208942804024	2.9248971104021e-13	Glucagon signaling pathway: G6PC
hsa04152__68	2.35807898623299e-14	DOWN	-7.62995577150458	2.95388694342119e-13	AMPK signaling pathway: PPARGC1A**
hsa04620__21	2.3776709489842e-14	UP	7.62888894323675	2.95870444578895e-13	Toll-like receptor signaling pathway: IFNA1
hsa04723__10	2.64741313530848e-14	UP	7.61502017575499	3.25130018382002e-13	Retrograde endocannabinoid signaling: CACNA1A
hsa04723__21	2.64741313530848e-14	UP	7.61502017575499	3.25130018382002e-13	Retrograde endocannabinoid signaling: CACNA1A*
hsa05030__37	2.97159576466716e-14	DOWN	-7.6000845800054	3.62573275442181e-13	Cocaine addiction: PRKACA
hsa05030__76	3.68049233768215e-14	DOWN	-7.57234704504188	4.461706517745e-13	Cocaine addiction: PDYN
hsa04012__8	3.74144784733847e-14	DOWN	-7.57021338850622	4.50652596483909e-13	ErbB signaling pathway: STAT5A
hsa05164__53	3.89821356198545e-14	DOWN	-7.56487924716709	4.66544158150997e-13	Influenza A: MAPK14
hsa05169__45	4.70661080733163e-14	DOWN	-7.54034219700705	5.59729221960515e-13	Epstein-Barr virus infection: RB1
hsa04620__20	5.67928479553323e-14	UP	7.51580514684701	6.71155731497292e-13	Toll-like receptor signaling pathway: IFNB1*
hsa04961__20	6.06183388179138e-14	UP	7.50727052070438	7.11886616492875e-13	Endocrine and other factor-regulated calcium reabsorption: CALB1*
hsa04510__19 26	6.46989064488466e-14	UP	7.49873589456176	7.55088479611073e-13	Focal adhesion: VCL ACTN4
hsa04750__44	7.07510186784635e-14	UP	7.48700078361565	8.15589963784251e-13	Inflammatory mediator regulation of TRP channels: TRPA1
hsa04750__63	7.07510186784635e-14	UP	7.48700078361565	8.15589963784251e-13	Inflammatory mediator regulation of TRP channels: TRPA1*
hsa05222__39	7.92666227184267e-14	UP	7.47206518786606	9.08182829804413e-13	Small cell lung cancer: BCL2L1
hsa04921__65	8.73605264751998e-14	UP	7.45926324865213	9.94851086344851e-13	Oxytocin signaling pathway: TRPM2
hsa04390__13	1.27650325420772e-13	UP	7.40912232006422	1.44490940641946e-12	Hippo signaling pathway: BIRC5
hsa04510__19 23	1.51100938639706e-13	UP	7.38671892643984	1.68999204585719e-12	Focal adhesion: VCL TLN1
hsa05164__78	1.51100938639706e-13	UP	7.38671892643984	1.68999204585719e-12	Influenza A: GSK3B
hsa05200__168	1.74533249781564e-13	UP	7.36751601761894	1.94052057005656e-12	Pathways in cancer: E2F1
hsa04340__31	2.19998761967584e-13	UP	7.33657799785193	2.41741329670813e-12	Hedgehog signaling pathway: GLI1***
hsa04720__4 15	2.19998761967584e-13	UP	7.33657799785193	2.41741329670813e-12	Long-term potentiation: CREBBP ATF4
hsa05200__210	2.32609674760493e-13	UP	7.32911019997714	2.54112545857539e-12	Pathways in cancer: MMP1
hsa05211__21	2.85978252508714e-13	UP	7.30137266501361	3.10608749401083e-12	Renal cell carcinoma: TGFB1*
hsa03320__26	2.975406826397e-13	DOWN	-7.29603852367447	3.21309737172411e-12	PPAR signaling pathway: CPT2
hsa04115__30	4.14628271533075e-13	UP	7.25123173642571	4.45192298406084e-12	p53 signaling pathway: SERPINE1
hsa05034__62	4.3127877191892e-13	DOWN	-7.24589759508657	4.60439097974802e-12	Alcoholism: NPY
hsa04390__79	4.38121282118664e-13	UP	7.24376393855091	4.65101632260434e-12	Hippo signaling pathway: SNAI2
hsa04024__77	4.5929476379404e-13	DOWN	-7.23736296894394	4.84839809645506e-12	cAMP signaling pathway: RHOA*
hsa04670__45	5.85753406662324e-13	UP	7.20429129264128	6.14877458725423e-12	Leukocyte transendothelial migration: PXN
hsa05205__236	6.23586469035711e-13	UP	7.19575666649866	6.50954986287834e-12	Proteoglycans in cancer: ITGAV
hsa05030__69	6.69020029674318e-13	DOWN	-7.18615521208821	6.94524108153615e-12	Cocaine addiction: PRKACA**
hsa04931__61	6.79549326017455e-13	DOWN	-7.18402155555255	7.01578672300439e-12	Insulin resistance: ACACB
hsa03320__20	8.00411450406145e-13	DOWN	-7.16161816192817	8.21843232411556e-12	PPAR signaling pathway: SCP2
hsa05231__60	8.45207100814005e-13	UP	7.15415036405337	8.6312181653778e-12	Choline metabolism in cancer: PRKCA
hsa04022__60	9.35020534538486e-13	UP	7.14028159657161	9.49677613188008e-12	cGMP-PKG signaling pathway: TRPC6*
hsa04530__20 31	9.42304885838062e-13	DOWN	-7.13921476830378	9.51930580908451e-12	Tight junction: ACTB MLLT4
hsa04024__25	9.72003354939452e-13	DOWN	-7.13494745523247	9.7668144595253e-12	cAMP signaling pathway: CFTR
hsa05164__68	9.9487818098296e-13	UP	7.13174697042899	9.94348990461161e-12	Influenza A: EIF2S1
hsa05222__34	1.10026009049857e-12	UP	7.11787820294723	1.09385646034223e-11	Small cell lung cancer: CCND1
hsa04727__26	1.29406311115826e-12	UP	7.09547480932284	1.25986766107066e-11	GABAergic synapse: KCNJ6
hsa05032__81	1.29406311115826e-12	UP	7.09547480932284	1.25986766107066e-11	Morphine addiction: KCNJ6
hsa05032__91	1.29406311115826e-12	UP	7.09547480932284	1.25986766107066e-11	Morphine addiction: KCNJ6**
hsa05032__85	1.29406311115826e-12	UP	7.09547480932284	1.25986766107066e-11	Morphine addiction: KCNJ6*
hsa05222__36	1.30408337886511e-12	UP	7.09440798105502	1.26307869530286e-11	Small cell lung cancer: PTGS2
hsa05164__36	1.31417976708346e-12	DOWN	-7.09334115278719	1.26633014479478e-11	Influenza A: IL33
hsa04530__20 22	1.3977600877535e-12	DOWN	-7.08480652664456	1.33999551269838e-11	Tight junction: ACTB MYL12B
hsa03320__22	1.74679500064037e-12	DOWN	-7.05386850687756	1.66610548538236e-11	PPAR signaling pathway: ACADM
hsa04724__51	1.76024415628284e-12	UP	7.05280167860973	1.6664802888463e-11	Glutamatergic synapse: ADRBK1
hsa04530__4 53	1.77379487902746e-12	DOWN	-7.0517348503419	1.6664802888463e-11	Tight junction: OCLN OCLN
hsa04530__4 45	1.77379487902746e-12	DOWN	-7.0517348503419	1.6664802888463e-11	Tight junction: OCLN TJP2
hsa04014__76	1.81506399200497e-12	UP	7.04853436553842	1.69676877660564e-11	Ras signaling pathway: RALBP1*
hsa04066__54	1.85727459102272e-12	UP	7.04533388073494	1.71912263868556e-11	HIF-1 signaling pathway: SERPINE1
hsa04370__36	1.85727459102272e-12	UP	7.04533388073494	1.71912263868556e-11	VEGF signaling pathway: NOS3
hsa05211__4	2.18093661590421e-12	UP	7.02293048711055	2.00881367710001e-11	Renal cell carcinoma: SLC2A1
hsa04530__13 45 20	2.26580573268074e-12	DOWN	-7.01759634577141	2.07680437644249e-11	Tight junction: EPB41 TJP2 ACTB
hsa04010__86	2.40837904514962e-12	UP	7.00906171962879	2.19676904166803e-11	MAPK signaling pathway: MAP4K2
hsa04976__34	2.67934663664936e-12	UP	6.9941261238792	2.43212189867834e-11	Bile secretion: SLCO1B1
hsa05160__53	2.7621112518793e-12	UP	6.98985881080789	2.48325695802929e-11	Hepatitis C: EIF2S1
hsa05162__74	2.7621112518793e-12	UP	6.98985881080789	2.48325695802929e-11	Measles: EIF2S1
hsa03320__40	2.98014819037193e-12	DOWN	-6.97919052812961	2.66652307128993e-11	PPAR signaling pathway: FABP4
hsa05152__120	3.36458611243038e-12	UP	6.96212127584437	2.99623568969511e-11	Tuberculosis: TGFB1
hsa04740__37	3.52094950712497e-12	UP	6.9557203062374	3.12069062447538e-11	Olfactory transduction: CNGB1*
hsa04066__37	3.60178115940476e-12	DOWN	-6.95251982143392	3.17734591479885e-11	HIF-1 signaling pathway: PDHA1
hsa04010__107	4.48313311611306e-12	UP	6.92158180166691	3.91804982566346e-11	MAPK signaling pathway: MAP3K2
hsa04340__20 22	4.48313311611306e-12	UP	6.92158180166691	3.91804982566346e-11	Hedgehog signaling pathway: GLI1 SUFU*
hsa04020__16	4.72571005052573e-12	UP	6.91411400379211	4.11093017821196e-11	Calcium signaling pathway: C06124
hsa04728__60	5.05657300423536e-12	UP	6.90451254938166	4.37847957371347e-11	Dopaminergic synapse: CACNA1A
hsa05161__26	5.0947083123224e-12	UP	6.90344572111384	4.39126464167605e-11	Hepatitis B: MMP9
hsa04068__58	5.28965395952184e-12	DOWN	-6.8981115797747	4.51784535906434e-11	FoxO signaling pathway: KLF2
hsa04931__149	5.28965395952184e-12	DOWN	-6.8981115797747	4.51784535906434e-11	Insulin resistance: ACACB*
hsa04650__40	5.87523148209517e-12	UP	6.88317598402511	4.97277475444001e-11	Natural killer cell mediated cytotoxicity: TNFRSF10D
hsa05032__38	5.87523148209517e-12	UP	6.88317598402511	4.97277475444001e-11	Morphine addiction: CACNA1A
hsa04152__64	6.23789620575876e-12	DOWN	-6.87464135788248	5.25605693749807e-11	AMPK signaling pathway: ACACB
hsa04611__92	6.82338211192143e-12	DOWN	-6.86183941866855	5.7237209769198e-11	Platelet activation: RHOA*
hsa04068__52	6.87453513997696e-12	DOWN	-6.86077259040072	5.74100067911854e-11	FoxO signaling pathway: CAT
hsa04110__10 11 12 13 14 9 15 16 17 18 19 20	7.40718347847792e-12	UP	6.85010430772244	6.15845033453983e-11	Cell cycle: ORC3 ORC5 ORC4 ORC2 ORC1 ORC6 MCM7 MCM6 MCM5 MCM4 MCM3 MCM2
hsa04010__14	7.68846783386065e-12	DOWN	-6.8447701663833	6.36415465190492e-11	MAPK signaling pathway: MAPT
hsa05205__215 216	8.34464510764438e-12	DOWN	-6.8330350554372	6.8770123496771e-11	Proteoglycans in cancer: EIF4B RPS6
hsa05205__150	8.53292781387782e-12	UP	6.82983457063372	7.00147221060106e-11	Proteoglycans in cancer: PRKCA
hsa05034__84	1.08190396200419e-11	DOWN	-6.79569606606323	8.83868497654731e-11	Alcoholism: FOSB
hsa05034__61	1.1226691301638e-11	DOWN	-6.79036192472409	9.13201426657045e-11	Alcoholism: CRH
hsa05020__24	1.2003244938649e-11	UP	6.71355028944048	9.59748818711554e-11	Prion diseases: PRNP*
hsa05020__26	1.2003244938649e-11	UP	6.71355028944048	9.59748818711554e-11	Prion diseases: PRNP**
hsa05020__25 8	1.2003244938649e-11	UP	6.71355028944048	9.59748818711554e-11	Prion diseases: PRNP PRNP*
hsa05020__10 34	1.2003244938649e-11	UP	6.71355028944048	9.59748818711554e-11	Prion diseases: PRNP PRNP***
hsa05110__46	1.2542042844218e-11	UP	6.77435950070667	9.98580445096845e-11	Vibrio cholerae infection: PLCG1
hsa05012__70	1.44264437320257e-11	DOWN	-6.75408976361794	1.14376741656018e-10	Parkinson's disease: PRKACA
hsa04150__33	1.45329562487871e-11	DOWN	-6.75302293535011	1.14737078955761e-10	mTOR signaling pathway: RPS6
hsa04725__25	1.47482969050016e-11	UP	6.75088927881446	1.15949999516728e-10	Cholinergic synapse: CACNA1A
hsa04922__70	1.59897142548178e-11	DOWN	-6.73915416786835	1.25186137853344e-10	Glucagon signaling pathway: PFKFB1
hsa03320__63	1.69562688516482e-11	DOWN	-6.73061954172573	1.32202610673224e-10	PPAR signaling pathway: DBI
hsa04921__33	1.77185073990013e-11	UP	6.72421857211876	1.37574691746791e-10	Oxytocin signaling pathway: C00942
hsa04933__30	1.85142673079028e-11	UP	6.71781760251179	1.43161762434359e-10	AGE-RAGE signaling pathway in diabetic complications: CXCL8
hsa04360__108	1.87872170018897e-11	DOWN	-6.71568394597614	1.44676970272749e-10	Axon guidance: CFL1
hsa03460__16 49	1.97739264842717e-11	UP	6.70821614810134	1.51653909648761e-10	Fanconi anemia pathway: FANCM C19orf40
hsa04750__39	2.304845694071e-11	UP	6.68581275447696	1.76048986144691e-10	Inflammatory mediator regulation of TRP channels: C01245*
hsa04390__59	2.35576196139805e-11	UP	6.68261226967348	1.79209584027001e-10	Hippo signaling pathway: SERPINE1
hsa04610__46	2.40777884444817e-11	UP	6.67941178486999	1.82428082609601e-10	Complement and coagulation cascades: C2
hsa04650__35	2.72448012534015e-11	UP	6.66127570431692	2.05594303434303e-10	Natural killer cell mediated cytotoxicity: BID
hsa04933__78	2.82514945159608e-11	UP	6.65594156297778	2.12338232781962e-10	AGE-RAGE signaling pathway in diabetic complications: TGFB1
hsa04932__58	3.01560822707026e-11	UP	6.64634010856733	2.25750113891037e-10	Non-alcoholic fatty liver disease (NAFLD): BAX
hsa05214__52	3.19541528586771e-11	UP	6.63780548242471	2.38261322307358e-10	Glioma: E2F1*
hsa04950__22	3.24198172222186e-11	UP	6.63567182588905	2.40778010120746e-10	Maturity onset diabetes of the young: NR5A2
hsa04530__11 43	3.4102537330819e-11	DOWN	-6.62820402801426	2.51288892723956e-10	Tight junction: TJP1 ACTN4
hsa05162__81	3.4102537330819e-11	UP	6.62820402801426	2.51288892723956e-10	Measles: TNFRSF10D
hsa05205__144	3.43497992254846e-11	UP	6.62713719974643	2.52122159158928e-10	Proteoglycans in cancer: NUDT16L1
hsa05152__23	3.51021588204228e-11	UP	6.62393671494295	2.56641853788227e-10	Tuberculosis: PPP3CA
hsa05221__21	3.56126661044446e-11	DOWN	-6.62180305840729	2.59365114768416e-10	Acute myeloid leukemia: PIM1
hsa05014__49	3.82761929195395e-11	DOWN	-6.61113477572901	2.7768712932747e-10	Amyotrophic lateral sclerosis (ALS): C00001
hsa04630__30	4.14313869666946e-11	UP	6.59939966478291	2.99421446578536e-10	Jak-STAT signaling pathway: CDKN1A
hsa04012__43	4.71514660017248e-11	UP	6.58019675596201	3.39454423820847e-10	ErbB signaling pathway: PTK2
hsa05133__73	4.74909566756255e-11	DOWN	-6.57912992769418	3.40593540433207e-10	Pertussis: FOS
hsa04622__44	5.10201193095554e-11	UP	6.5684616450159	3.64512563432147e-10	RIG-I-like receptor signaling pathway: MAPK8
hsa04340__51	5.72070623922347e-11	UP	6.55139239273065	4.07166932708367e-10	Hedgehog signaling pathway: CCND1*
hsa05030__77	6.14404406322711e-11	DOWN	-6.54072411005238	4.35647501690707e-10	Cocaine addiction: BDNF
hsa04014__55	6.36705359217604e-11	DOWN	-6.53538996871324	4.49762921041308e-10	Ras signaling pathway: MLLT4
hsa05100__24	6.41259614913157e-11	UP	6.53432314044541	4.51283451843379e-10	Bacterial invasion of epithelial cells: ACTB
hsa05131__38	7.08465076550209e-11	UP	6.51938754469582	4.96718611506658e-10	Shigellosis: CXCL8
hsa04933__61	7.34098311600904e-11	UP	6.51405340335668	5.12777222118252e-10	AGE-RAGE signaling pathway in diabetic complications: MMP2
hsa04810__32	7.66057178989268e-11	UP	6.50765243374971	5.33119051600309e-10	Regulation of actin cytoskeleton: PXN
hsa05161__125	7.77009452374953e-11	UP	6.50551877721406	5.38745668270309e-10	Hepatitis B: CDKN1A
hsa04921__76	8.76499391653421e-11	UP	6.48738269666099	6.05493513572345e-10	Oxytocin signaling pathway: CDKN1A
hsa05205__120	9.01660682140642e-11	UP	6.48311538358967	6.20593561077753e-10	Proteoglycans in cancer: PLAU
hsa04520__34	9.74550789656208e-11	DOWN	-6.47138027264357	6.68314209402925e-10	Adherens junction: RHOA
hsa04910__17	1.06814353992446e-10	DOWN	-6.45751150516181	7.2983334964293e-10	Insulin signaling pathway: C00031
hsa05162__27 70	1.11425012393614e-10	UP	6.45111053555484	7.58578254665217e-10	Measles: STAT1 GNB2L1
hsa04066__11	1.17876263258362e-10	UP	6.44257590941222	7.99601078203837e-10	HIF-1 signaling pathway: SLC2A1
hsa04211__38	1.21237391281096e-10	UP	6.4383085963409	8.19442655457478e-10	Longevity regulating pathway - mammal: BAX
hsa04970__28	1.30053974430662e-10	DOWN	-6.42764031366263	8.75883218477471e-10	Salivary secretion: AQP5
hsa05132__41	1.32820641867075e-10	UP	6.42443982885914	8.91321378815123e-10	Salmonella infection: ACTB*
hsa05200__211	1.35643837575282e-10	UP	6.42123934405566	9.070276541066e-10	Pathways in cancer: CXCL8
hsa05168__122	1.36597790299633e-10	UP	6.42017251578783	9.10167546003584e-10	Herpes simplex infection: CASP3
hsa04068__67	1.38525406839534e-10	DOWN	-6.41803885925218	9.19749962726091e-10	FoxO signaling pathway: GABARAP
hsa04064__53	1.54933688585413e-10	UP	6.40096960696693	1.02507183398589e-09	NF-kappa B signaling pathway: CXCL8
hsa05150__40	1.56020000725002e-10	UP	6.3999027786991	1.02863712758694e-09	Staphylococcus aureus infection: FCGR1A
hsa04727__13	1.59323786303425e-10	UP	6.39670229389562	1.04674613448998e-09	GABAergic synapse: CACNA1A
hsa04932__28	1.80630575427439e-10	UP	6.37749938507472	1.18259530044654e-09	Non-alcoholic fatty liver disease (NAFLD): GSK3A
hsa04740__10	1.83163245873411e-10	UP	6.37536572853906	1.19501298262549e-09	Olfactory transduction: ANO2
hsa05166__65	1.92303782799774e-10	UP	6.36789793066427	1.25030729370511e-09	HTLV-I infection: PTTG2
hsa04151__34	1.97725469076744e-10	DOWN	-6.36363061759296	1.28112467722483e-09	PI3K-Akt signaling pathway: GYS1
hsa04340__50	2.03296388876664e-10	DOWN	-6.35936330452165	1.31269386494588e-09	Hedgehog signaling pathway: BCL2
hsa05219__12	2.09020545659055e-10	DOWN	-6.35509599145033	1.34503289484029e-09	Bladder cancer: ERBB2
hsa05168__123	2.10476007197585e-10	UP	6.35402916318251	1.34977616902478e-09	Herpes simplex infection: CYCS
hsa03460__25 40	2.30322117620032e-10	UP	6.34016039570075	1.47202469050354e-09	Fanconi anemia pathway: MLH1 PMS2
hsa05200__207	2.48533193508307e-10	UP	6.32842528475464	1.58303006983766e-09	Pathways in cancer: CDK4
hsa04742__48	2.50256825741629e-10	UP	6.32735845648681	1.58862356610987e-09	Taste transduction: GABBR1
hsa05162__27 28	2.79476105915526e-10	UP	6.31028920420157	1.76813334348577e-09	Measles: STAT1 IRF9
hsa04933__65	2.83354964096252e-10	UP	6.30815554766591	1.78665764274113e-09	AGE-RAGE signaling pathway in diabetic complications: COL1A1
hsa04810__82 83	2.89272009772063e-10	UP	6.30495506286243	1.81786657646056e-09	Regulation of actin cytoskeleton: ACTB ARPC5
hsa04970__18	2.91271041435425e-10	DOWN	-6.3038882345946	1.82432762285722e-09	Salivary secretion: VAMP2
hsa04022__59	2.97349419682909e-10	UP	6.30068774979112	1.85621116140925e-09	cGMP-PKG signaling pathway: NPPB
hsa04670__10	3.01470302018426e-10	UP	6.29855409325546	1.87570429633318e-09	Leukocyte transendothelial migration: BCAR1
hsa04922__37	3.0564693371478e-10	DOWN	-6.2964204367198	1.88917956726997e-09	Glucagon signaling pathway: PYGB
hsa05133__46	3.0564693371478e-10	DOWN	-6.2964204367198	1.88917956726997e-09	Pertussis: CFL1
hsa03460__28	3.5548642085104e-10	UP	6.27295021482759	2.19002945829214e-09	Fanconi anemia pathway: RAD51C
hsa05031__8	3.70392325234845e-10	DOWN	-6.26654924522063	2.27440254613161e-09	Amphetamine addiction: DRD1
hsa04360__18	3.75509253262953e-10	UP	6.26441558868497	2.29831233511755e-09	Axon guidance: PTK2
hsa05164__41 42	4.21781868204628e-10	UP	6.2462795081319	2.57314328037823e-09	Influenza A: STAT1 IRF9
hsa04068__13	4.45439660477358e-10	DOWN	-6.23774488198927	2.69993910334502e-09	FoxO signaling pathway: PCK1
hsa04931__104	4.45439660477358e-10	DOWN	-6.23774488198927	2.69993910334502e-09	Insulin resistance: C00369*
hsa04068__47	4.6087833019655e-10	DOWN	-6.23241074065014	2.77561020012602e-09	FoxO signaling pathway: GADD45G
hsa04068__54	4.6087833019655e-10	DOWN	-6.23241074065014	2.77561020012602e-09	FoxO signaling pathway: GADD45G*
hsa04062__60	4.64028142332913e-10	UP	6.23134391238231	2.7856513720241e-09	Chemokine signaling pathway: GSK3A
hsa05030__78	4.73604168607822e-10	DOWN	-6.22814342757882	2.83408354399394e-09	Cocaine addiction: GRIA2
hsa04540__16 17	5.35243467967357e-10	UP	6.20894051875792	3.1927697660656e-09	Gap junction: GJA1 GJA1**
hsa04960__27	6.21273225968297e-10	DOWN	-6.18547029686571	3.6942164290963e-09	Aldosterone-regulated sodium reabsorption: KCNJ1
hsa04010__57	6.38302932038986e-10	UP	6.1812029837944	3.78350539211752e-09	MAPK signaling pathway: NLK
hsa04380__68	6.73739573698435e-10	UP	6.17266835765178	3.96851617234909e-09	Osteoclast differentiation: TGFBR1
hsa05100__15	6.73739573698435e-10	DOWN	-6.17266835765178	3.96851617234909e-09	Bacterial invasion of epithelial cells: CTNNA1
hsa04950__30	6.82894369452106e-10	UP	6.17053470111612	4.00987037562659e-09	Maturity onset diabetes of the young: PAX6*
hsa05160__22 23	7.01569475481965e-10	UP	6.16626738804481	4.10669484246297e-09	Hepatitis C: STAT1 IRF9
hsa05145__11	8.41316400935717e-10	DOWN	-6.13746302481346	4.9094208613609e-09	Toxoplasmosis: MAPK14
hsa04540__18 19	9.49185199513261e-10	UP	6.11826011599256	5.5217306188403e-09	Gap junction: GJA1 GJA1***
hsa04210__24	9.94696399773387e-10	UP	6.11079231811776	5.76862510856233e-09	Apoptosis: CASP10
hsa04670__55	1.02164386898875e-09	UP	6.10652500504645	5.90667332255342e-09	Leukocyte transendothelial migration: RAC2
hsa05205__158	1.07052465410298e-09	DOWN	-6.09905720717166	6.17029394190028e-09	Proteoglycans in cancer: PDCD4
hsa05200__121 122	1.08490450264476e-09	UP	6.096923550636	6.21504744045578e-09	Pathways in cancer: SMAD2 SMAD4
hsa05212__38 39	1.08490450264476e-09	UP	6.096923550636	6.21504744045578e-09	Pancreatic cancer: SMAD2 SMAD4
hsa04722__73 77	1.10682802814946e-09	UP	6.09372306583252	6.32136737049495e-09	Neurotrophin signaling pathway: NGFRAP1 YWHAE
hsa04662__32 51	1.12918328341751e-09	DOWN	-6.09052258102904	6.41007670556343e-09	B cell receptor signaling pathway: BLNK GRB2
hsa04950__16	1.12918328341751e-09	UP	6.09052258102904	6.41007670556343e-09	Maturity onset diabetes of the young: PAX4
hsa04530__11 20 16	1.198922882321e-09	DOWN	-6.08092112661858	6.78547016831677e-09	Tight junction: TJP1 ACTB CTTN
hsa05205__34	1.20692616710952e-09	UP	6.07985429835076	6.81025305705342e-09	Proteoglycans in cancer: SLC9A1
hsa04370__23	1.24773033432173e-09	UP	6.07452015701162	7.0194170604507e-09	VEGF signaling pathway: PTK2
hsa05168__29	1.29847275588268e-09	UP	6.06811918740465	7.28307554717478e-09	Herpes simplex infection: IKBKG
hsa04540__21	1.32459066152321e-09	DOWN	-6.06491870260117	7.38548906275135e-09	Gap junction: C03758
hsa04620__18	1.32459276963662e-09	UP	6.06491870260117	7.38548906275135e-09	Toll-like receptor signaling pathway: CXCL11
hsa04068__45	1.38754713079946e-09	DOWN	-6.05745090472637	7.71361259991771e-09	FoxO signaling pathway: RBL2
hsa04024__123	1.41541177125973e-09	UP	6.05425041992289	7.84530595338358e-09	cAMP signaling pathway: PAK1
hsa04071__68	1.54259245866634e-09	UP	6.04038165244113	8.50009158309104e-09	Sphingolipid signaling pathway: NFKB1
hsa04152__81	1.54259245866634e-09	DOWN	-6.04038165244113	8.50009158309104e-09	AMPK signaling pathway: LIPE
hsa03460__16 34	1.7602802219524e-09	UP	6.01904508708457	9.67124718435254e-09	Fanconi anemia pathway: FANCM STRA13
hsa05168__91 92	1.93018261470764e-09	UP	6.00410949133498	1.05737992216783e-08	Herpes simplex infection: STAT1 IRF9
hsa04012__47	1.94291190358736e-09	UP	6.00304266306715	1.0612591473374e-08	ErbB signaling pathway: PRKCA
hsa04933__29	2.08844515005408e-09	UP	5.99130755212105	1.13744592375409e-08	AGE-RAGE signaling pathway in diabetic complications: ICAM1
hsa05166__74	2.12994499497357e-09	UP	5.98810706731756	1.15669556229923e-08	HTLV-I infection: NFKB1
hsa05205__22	2.22992661992892e-09	UP	5.98063926944277	1.20750205154076e-08	Proteoglycans in cancer: PPP1R12A
hsa04010__15	2.24457782886922e-09	DOWN	-5.97957244117494	1.21194302886358e-08	MAPK signaling pathway: NFKB1
hsa05217__5	2.33447442513859e-09	UP	5.97317147156797	1.25687032803307e-08	Basal cell carcinoma: BMP2
hsa05205__400	2.38072646471504e-09	UP	5.96997098676449	1.2781100077713e-08	Proteoglycans in cancer: ITGA2*
hsa04014__104	2.39634370337912e-09	UP	5.96890415849666	1.28282900816221e-08	Ras signaling pathway: BRAP*
hsa05152__20	2.44377955399672e-09	UP	5.96570367369318	1.30450618805677e-08	Tuberculosis: FCGR1A
hsa05010__61	2.47592930986525e-09	UP	5.96357001715752	1.31420089639458e-08	Alzheimer's disease: GAPDH
hsa05220__19 41	2.47592930986525e-09	UP	5.96357001715752	1.31420089639458e-08	Chronic myeloid leukemia: SMAD4 SMAD3
hsa04072__57	2.54144587992516e-09	UP	5.95930270408621	1.34517656574067e-08	Phospholipase D signaling pathway: C06124
hsa04620__19	2.85776945134652e-09	UP	5.94009979526531	1.50835640423599e-08	Toll-like receptor signaling pathway: CXCL10
hsa04921__57	2.99086942972348e-09	DOWN	-5.93263199739052	1.57418589872561e-08	Oxytocin signaling pathway: FOS
hsa04115__38	3.23321337596736e-09	UP	5.91983005817658	1.6969854562689e-08	p53 signaling pathway: GTSE1
hsa04068__51	3.31816447222923e-09	DOWN	-5.91556274510527	1.73189751203298e-08	FoxO signaling pathway: BCL6
hsa04068__56	3.31816447222923e-09	DOWN	-5.91556274510527	1.73189751203298e-08	FoxO signaling pathway: BCL6*
hsa04976__95 96	3.33937508793207e-09	UP	5.91449591683744	1.73814010809539e-08	Bile secretion: SLC51A SLC51B
hsa05211__42	3.38329995744971e-09	UP	5.91236226030179	1.75613829283094e-08	Renal cell carcinoma: SLC2A1*
hsa04010__54	3.49463523577252e-09	DOWN	-5.90702811896265	1.80893102149217e-08	MAPK signaling pathway: NR4A1
hsa04917__34	3.5631399067299e-09	DOWN	-5.90382763415917	1.83932414416085e-08	Prolactin signaling pathway: ELF5
hsa04666__51	3.85046857844646e-09	UP	5.89102569494523	1.97678427838822e-08	Fc gamma R-mediated phagocytosis: NCF1
hsa05132__13	3.85046857844646e-09	DOWN	-5.89102569494523	1.97678427838822e-08	Salmonella infection: FOS
hsa04340__13	3.9511640431626e-09	UP	5.88675838187392	2.01745577095178e-08	Hedgehog signaling pathway: GLI1*
hsa04962__10	3.9511640431626e-09	DOWN	-5.88675838187392	2.01745577095178e-08	Vasopressin-regulated water reabsorption: AQP2
hsa04068__44	4.08064262763312e-09	DOWN	-5.88142424053478	2.07792073098174e-08	FoxO signaling pathway: CDKN1B
hsa05160__15 16	4.21424725881943e-09	DOWN	-5.87609009919564	2.14015421603289e-08	Hepatitis C: TRAF6 RIPK1
hsa05161__45	4.26887285094367e-09	UP	5.87395644265999	2.16205177545098e-08	Hepatitis B: PCNA
hsa04726__72	4.43691666252612e-09	UP	5.86755547305302	2.24112000238886e-08	Serotonergic synapse: KCNJ3
hsa04630__24	4.73139786036292e-09	UP	5.85688719037474	2.38345752804877e-08	Jak-STAT signaling pathway: MCL1
hsa05162__28 34	5.84446313906187e-09	UP	5.82168185753642	2.93629578564098e-08	Measles: IRF9 STAT1
hsa04933__57	6.34960241211024e-09	UP	5.80781309005466	3.17311248200934e-08	AGE-RAGE signaling pathway in diabetic complications: FIGF
hsa05231__59	6.34960241211024e-09	DOWN	-5.80781309005466	3.17311248200934e-08	Choline metabolism in cancer: PLA2G4B
hsa04360__33 134	6.89710801772547e-09	UP	5.7939443225729	3.4375771791263e-08	Axon guidance: NCK1 PAK4
hsa05168__92 93	7.3027658481768e-09	UP	5.78434286816245	3.63013148908048e-08	Herpes simplex infection: IRF9 STAT1
hsa04550__34	7.58599584441355e-09	DOWN	-5.77794189855548	3.76097260993485e-08	Signaling pathways regulating pluripotency of stem cells: MAPK1*
hsa04022__23	7.63422787046662e-09	DOWN	-5.77687507028766	3.77492478121231e-08	cGMP-PKG signaling pathway: CACNA1C
hsa04520__4	7.92994390858903e-09	DOWN	-5.77047410068069	3.91085685150625e-08	Adherens junction: CTNND1
hsa04916__15	8.18485585423062e-09	DOWN	-5.76513995934155	4.02600632201553e-08	Melanogenesis: MITF*
hsa04621__29	8.34160860194541e-09	UP	5.76193947453807	4.0923975360458e-08	NOD-like receptor signaling pathway: CASP5
hsa04630__28	8.60937184321161e-09	UP	5.75660533319893	4.21276294098818e-08	Jak-STAT signaling pathway: CCND1
hsa04666__38	8.663918382963e-09	DOWN	-5.7555385049311	4.22844224456817e-08	Fc gamma R-mediated phagocytosis: CFL1
hsa05321__94	9.22819444144394e-09	DOWN	-5.74487022225282	4.49217029934538e-08	Inflammatory bowel disease (IBD): IL22
hsa05161__44	1.00153897179673e-08	UP	5.73100145477106	4.86276932301306e-08	Hepatitis B: CXCL8
hsa04115__29	1.02061136955862e-08	DOWN	-5.72780096996758	4.94259990567177e-08	p53 signaling pathway: IGF1
hsa05160__66	1.05982095260382e-08	UP	5.72140000036061	5.11928938288578e-08	Hepatitis C: GSK3B
hsa04620__77	1.10049296299417e-08	UP	5.71499903075364	5.30211866016934e-08	Toll-like receptor signaling pathway: CXCL9
hsa04064__52	1.12139381243372e-08	UP	5.71179854595016	5.38899993238608e-08	NF-kappa B signaling pathway: TRAF1
hsa04931__140	1.15708874919733e-08	DOWN	-5.70646440461102	5.54635142791273e-08	Insulin resistance: G00369
hsa04520__10	1.1864373735737e-08	UP	5.70219709153971	5.67255935100505e-08	Adherens junction: NLK
hsa04068__66	1.20892226405042e-08	DOWN	-5.69899660673622	5.76539323388512e-08	FoxO signaling pathway: BNIP3
hsa04623__8	1.27888960126008e-08	UP	5.68939515232577	6.0836292677663e-08	Cytosolic DNA-sensing pathway: TBK1
hsa04650__116	1.28690240979278e-08	UP	5.68832832405795	6.10628693939555e-08	Natural killer cell mediated cytotoxicity: FCGR3A
hsa04520__9 57	1.31944421536472e-08	DOWN	-5.68406101098664	6.22923537856862e-08	Adherens junction: LEF1 CTNNB1
hsa04930__7	1.31944421536472e-08	DOWN	-5.68406101098664	6.22923537856862e-08	Type II diabetes mellitus: C00002
hsa04621__4 7 8	1.34437381435722e-08	UP	5.68086052618315	6.31519599294303e-08	NOD-like receptor signaling pathway: IKBKG CHUK IKBKB
hsa04726__71	1.34437381435722e-08	UP	5.68086052618315	6.31519599294303e-08	Serotonergic synapse: CACNA1A
hsa04213__55	1.44874776378787e-08	DOWN	-5.66805858696922	6.78852131710076e-08	Longevity regulating pathway - multiple species: CRYAB
hsa03320__27	1.55130995623647e-08	DOWN	-5.65632347602311	7.25102340240875e-08	PPAR signaling pathway: CPT1C
hsa04370__25	1.56097597964622e-08	UP	5.65525664775528	7.27809892246959e-08	VEGF signaling pathway: PXN
hsa04071__57	1.66091023658271e-08	UP	5.64458836507701	7.72487706569039e-08	Sphingolipid signaling pathway: BAX
hsa04115__18	1.75614339543955e-08	DOWN	-5.63498691066656	8.12757004933721e-08	p53 signaling pathway: CCNG1
hsa04919__102	1.75614339543955e-08	DOWN	-5.63498691066656	8.12757004933721e-08	Thyroid hormone signaling pathway: BMP4
hsa04152__24	1.89140461786412e-08	DOWN	-5.62218497145262	8.73206210556923e-08	AMPK signaling pathway: SIRT1
hsa05211__3	1.97492253249383e-08	UP	5.61471717357783	9.0952927415586e-08	Renal cell carcinoma: VEGFA
hsa04530__30	2.0747588633617e-08	UP	5.6061825474352	9.5084680591625e-08	Tight junction: AKT3
hsa04930__15	2.0747588633617e-08	DOWN	-5.6061825474352	9.5084680591625e-08	Type II diabetes mellitus: C00031*
hsa05120__18	2.3898556721039e-08	UP	5.58164549727516	1.09258851773315e-07	Epithelial cell signaling in Helicobacter pylori infection: CCL5
hsa04919__104	2.47940963489572e-08	DOWN	-5.5752445276682	1.13077929707987e-07	Thyroid hormone signaling pathway: MYC
hsa05160__58	2.52539954969786e-08	DOWN	-5.57204404286471	1.14896507357925e-07	Hepatitis C: EIF3E
hsa04210__102	2.78500958528782e-08	DOWN	-5.55497479057947	1.26401763544827e-07	Apoptosis: PIDD1
hsa05217__3	2.8192274479128e-08	UP	5.55284113404381	1.27646466858509e-07	Basal cell carcinoma: GLI1
hsa03320__56	2.90656643702281e-08	UP	5.54750699270467	1.30969744248582e-07	PPAR signaling pathway: FADS2
hsa04724__3	2.90656643702281e-08	DOWN	-5.54750699270467	1.30969744248582e-07	Glutamatergic synapse: GRIK1
hsa04668__47	2.92434656743154e-08	UP	5.54644016443685	1.31455674646025e-07	TNF signaling pathway: CASP7
hsa04914__34	2.94223220632114e-08	DOWN	-5.54537333616902	1.31944017080607e-07	Progesterone-mediated oocyte maturation: MAPK14
hsa04916__7	3.12702647035677e-08	DOWN	-5.53470505349074	1.39897208042866e-07	Melanogenesis: TYRP1
hsa04024__76	3.22359771348255e-08	UP	5.5293709121516	1.43875061844031e-07	cAMP signaling pathway: C00416
hsa04520__18	3.40476597580552e-08	UP	5.51976945774115	1.51242441336609e-07	Adherens junction: SNAI2
hsa04950__8	3.40476597580552e-08	UP	5.51976945774115	1.51242441336609e-07	Maturity onset diabetes of the young: NEUROD1
hsa05142__67	3.44634668857361e-08	UP	5.5176358012055	1.52369068890113e-07	Chagas disease (American trypanosomiasis): IFNGR1*
hsa05169__103	3.44634668857361e-08	UP	5.5176358012055	1.52369068890113e-07	Epstein-Barr virus infection: NFKB1*
hsa04213__71	3.48841976500729e-08	DOWN	-5.51550214466984	1.53867153484711e-07	Longevity regulating pathway - multiple species: SIRT1**
hsa04921__55	3.53099084145633e-08	UP	5.51336848813418	1.55017097922814e-07	Oxytocin signaling pathway: PTGS2*
hsa05205__69	3.53099084145633e-08	DOWN	-5.51336848813418	1.55017097922814e-07	Proteoglycans in cancer: MAPK1*
hsa04921__48	3.55246490802315e-08	UP	5.51230165986636	1.55596306810618e-07	Oxytocin signaling pathway: PRKAG2
hsa04623__17	3.68399419986402e-08	UP	5.50590069025939	1.60981979105686e-07	Cytosolic DNA-sensing pathway: NFKB1
hsa05162__13	3.77429134526705e-08	UP	5.50163337718808	1.64545091363266e-07	Measles: IRF7
hsa04360__58	3.79719885081141e-08	UP	5.50056654892025	1.65160570385987e-07	Axon guidance: PLXNC1
hsa04919__32	3.84341904973546e-08	DOWN	-5.49843289238459	1.66784858994294e-07	Thyroid hormone signaling pathway: PLN
hsa04012__31	3.86673328119387e-08	UP	5.49736606411677	1.67409950123578e-07	ErbB signaling pathway: BAD
hsa05222__44	3.91377388495478e-08	UP	5.49523240758111	1.69057037467357e-07	Small cell lung cancer: RB1
hsa04742__34	3.9375018207529e-08	UP	5.49416557931328	1.69691878926484e-07	Taste transduction: GRM1
hsa05168__106 134	3.96136922863141e-08	DOWN	-5.49309875104545	1.70329811913007e-07	Herpes simplex infection: SRSF8 C1QBP
hsa05032__25	4.00952563492254e-08	DOWN	-5.4909650945098	1.72006818904554e-07	Morphine addiction: C00575*
hsa04510__42	4.15742550177721e-08	UP	5.48456412490283	1.779453876501e-07	Focal adhesion: BIRC2
hsa04064__137	4.52338970475346e-08	UP	5.46962852915324	1.93169301255267e-07	NF-kappa B signaling pathway: ICAM1
hsa04213__60	4.68962198901647e-08	DOWN	-5.46322755954628	1.9981405254789e-07	Longevity regulating pathway - multiple species: CAT
hsa04360__96	4.77494384816893e-08	UP	5.46002707474279	2.02989128749082e-07	Axon guidance: GSK3B
hsa04724__13	5.00983278210269e-08	UP	5.45149244860017	2.12017688138759e-07	Glutamatergic synapse: GRM5
hsa04261__62	5.00989108747255e-08	DOWN	-5.45149244860017	2.12017688138759e-07	Adrenergic signaling in cardiomyocytes: BCL2
hsa04071__48	5.10082073429957e-08	DOWN	-5.44829196379669	2.15380722690986e-07	Sphingolipid signaling pathway: SMPD1
hsa04750__60	5.13148898250062e-08	UP	5.44722513552886	2.16189860944365e-07	Inflammatory mediator regulation of TRP channels: TRPV3
hsa04919__100	5.2246305167475e-08	DOWN	-5.44402465072538	2.19621493086545e-07	Thyroid hormone signaling pathway: CTNNB1*
hsa04650__16	5.64733883939963e-08	UP	5.43015588324361	2.36860483911427e-07	Natural killer cell mediated cytotoxicity: PRKCA
hsa04931__13	5.78394170841285e-08	DOWN	-5.4258885701723	2.42049587307522e-07	Insulin resistance: AKT2
hsa04620__66	6.28772617870919e-08	UP	5.41095297442271	2.62547499773213e-07	Toll-like receptor signaling pathway: CASP8
hsa04370__39	6.40108299875571e-08	UP	5.40775248961923	2.66688136467006e-07	VEGF signaling pathway: RAC1
hsa05014__53	6.59442479180718e-08	DOWN	-5.40241834828009	2.74135490792161e-07	Amyotrophic lateral sclerosis (ALS): RAB5A
hsa04115__9	6.67333525398059e-08	DOWN	-5.40028469174443	2.76803464508378e-07	p53 signaling pathway: RPRM
hsa04064__136	6.75316011756915e-08	UP	5.39815103520878	2.79497529976045e-07	NF-kappa B signaling pathway: TNFSF13B*
hsa05152__112	7.08180980943554e-08	UP	5.38961640906616	2.92455398503942e-07	Tuberculosis: IFNGR1
hsa04360__131	7.20900444124115e-08	DOWN	-5.38641592426267	2.9705524879588e-07	Axon guidance: RAC1****
hsa04330__19	7.51445645774407e-08	DOWN	-5.37894812638788	3.08964194400462e-07	Notch signaling pathway: DTX2
hsa05215__39	7.92564317929574e-08	UP	5.36934667197743	3.25159029124382e-07	Prostate cancer: RB1
hsa04925__33	8.60890765858635e-08	DOWN	-5.35441107622784	3.52421296088971e-07	Aldosterone synthesis and secretion: CYP11B2
hsa04014__68	9.1315181932503e-08	UP	5.34374279354956	3.73002667067768e-07	Ras signaling pathway: RALGDS*
hsa04666__41	9.4596903529536e-08	UP	5.33734182394259	3.85569591609541e-07	Fc gamma R-mediated phagocytosis: MARCKS
hsa04072__27	9.91505883229542e-08	UP	5.32880719779997	4.03255314845955e-07	Phospholipase D signaling pathway: C01245
hsa04064__51	9.97345042845627e-08	UP	5.32774036953214	4.04754068144046e-07	NF-kappa B signaling pathway: TNFAIP3
hsa04921__77	1.00321748213608e-07	UP	5.32667354126431	4.06259838132263e-07	Oxytocin signaling pathway: KCNJ3
hsa04921__28	1.00912338405327e-07	DOWN	-5.32560671299649	4.07772653470127e-07	Oxytocin signaling pathway: EEF2
hsa04723__46	1.06381298876144e-07	UP	5.31600525858604	4.28949486240931e-07	Retrograde endocannabinoid signaling: ADCY1
hsa04540__10	1.08903023115215e-07	UP	5.31173794551473	4.38177260028885e-07	Gap junction: C00533
hsa04750__40	1.09542436984381e-07	DOWN	-5.3106711172469	4.39808203191565e-07	Inflammatory mediator regulation of TRP channels: C00219
hsa04151__105 62	1.10832182309425e-07	UP	5.30853746071124	4.44037677098956e-07	PI3K-Akt signaling pathway: CCND1 CDK2
hsa05205__256	1.14121167609519e-07	UP	5.3032033193721	4.56241859443164e-07	Proteoglycans in cancer: ACTB
hsa04115__40	1.20280872366662e-07	DOWN	-5.29360186496165	4.79846622456388e-07	p53 signaling pathway: PIDD1
hsa04211__56	1.20984818767892e-07	DOWN	-5.29253503669382	4.81632361154385e-07	Longevity regulating pathway - mammal: CAT
hsa04068__59	1.22404689762063e-07	DOWN	-5.29040138015817	4.8625457095754e-07	FoxO signaling pathway: S1PR1
hsa04068__14	1.28996113572128e-07	DOWN	-5.28079992574772	5.11358011396686e-07	FoxO signaling pathway: G6PC
hsa04610__52	1.35142402247285e-07	UP	5.2722652996051	5.34594892258209e-07	Complement and coagulation cascades: CPB2
hsa04922__36	1.39126683153171e-07	DOWN	-5.26693115826596	5.49199658917664e-07	Glucagon signaling pathway: GYS1
hsa03320__59	1.44896071228963e-07	DOWN	-5.25946336039116	5.70775089809688e-07	PPAR signaling pathway: NR1H3
hsa05211__23	1.62683993319124e-07	UP	5.23812679503461	6.39504651561996e-07	Renal cell carcinoma: PDGFB
hsa04152__60	1.64574710542157e-07	UP	5.23599313849895	6.4558639062362e-07	AMPK signaling pathway: EEF2
hsa04068__88	1.65528019465968e-07	DOWN	-5.23492631023112	6.47973226201155e-07	FoxO signaling pathway: FBXO32
hsa05162__105	1.66486666746699e-07	UP	5.23385948196329	6.50370991303635e-07	Measles: GSK3B
hsa05034__99	1.87903763204185e-07	DOWN	-5.21145608833891	7.27981796001366e-07	Alcoholism: PDYN
hsa05200__225	1.87903763204185e-07	UP	5.21145608833891	7.27981796001366e-07	Pathways in cancer: PPARD
hsa05221__11	1.87903763204185e-07	UP	5.21145608833891	7.27981796001366e-07	Acute myeloid leukemia: PPARD
hsa05321__138	1.87903763204185e-07	UP	5.21145608833891	7.27981796001366e-07	Inflammatory bowel disease (IBD): IFNG**
hsa04919__11	1.88987410346254e-07	DOWN	-5.21038926007108	7.30673547408664e-07	Thyroid hormone signaling pathway: CTNNB1
hsa04064__114	1.96743878975118e-07	UP	5.20292146219629	7.59100099782848e-07	NF-kappa B signaling pathway: BCL2A1*
hsa04012__57	1.97876760756748e-07	UP	5.20185463392846	7.61906625946578e-07	ErbB signaling pathway: ABL1
hsa05142__64	1.99015946277485e-07	UP	5.20078780566063	7.64725895818802e-07	Chagas disease (American trypanosomiasis): CASP8
hsa04931__35	2.05985341364335e-07	DOWN	-5.19438683605367	7.89890727395071e-07	Insulin resistance: C00369
hsa05205__220	2.15645668073711e-07	UP	5.18585220991104	8.25250937495934e-07	Proteoglycans in cancer: FAS
hsa04151__103	2.20638579084696e-07	DOWN	-5.18158489683973	8.42642053049073e-07	PI3K-Akt signaling pathway: BCL2*
hsa05215__13	2.21904154271473e-07	DOWN	-5.1805180685719	8.45756401371397e-07	Prostate cancer: BCL2
hsa04152__103	2.24456381419731e-07	UP	5.17838441203625	8.52027354924595e-07	AMPK signaling pathway: ULK1
hsa04668__48	2.24456381419731e-07	UP	5.17838441203625	8.52027354924595e-07	TNF signaling pathway: CASP3
hsa04919__31	2.3629667221427e-07	DOWN	-5.1687829576258	8.9516420784398e-07	Thyroid hormone signaling pathway: ATP2A2
hsa04914__15	2.44523056889894e-07	UP	5.16238198801883	9.24464434398615e-07	Progesterone-mediated oocyte maturation: ANAPC10
hsa05166__60	2.5885219521943e-07	UP	5.15171370534055	9.76673242605038e-07	HTLV-I infection: POLD3
hsa04630__31	2.64808095141441e-07	UP	5.14744639226924	9.9714310775705e-07	Jak-STAT signaling pathway: BCL2L1
hsa04020__7	2.69361661781201e-07	UP	5.14424590746576	1.01226112497375e-06	Calcium signaling pathway: ADCY1
hsa04012__48	2.7869675007057e-07	UP	5.13784493785879	1.0452518829992e-06	ErbB signaling pathway: CAMK2A
hsa04726__10	2.85092904649541e-07	DOWN	-5.13357762478748	1.06711069290137e-06	Serotonergic synapse: PRKACA
hsa05218__21	2.89982813760167e-07	UP	5.130377139984	1.08110656161777e-06	Melanoma: RB1
hsa05220__40	2.89982813760167e-07	UP	5.130377139984	1.08110656161777e-06	Chronic myeloid leukemia: RB1
hsa04071__24	3.00006755306215e-07	UP	5.12397617037703	1.11626275885223e-06	Sphingolipid signaling pathway: PTEN
hsa04024__112	3.05143383680241e-07	UP	5.12077568557354	1.13313126074145e-06	cAMP signaling pathway: GLI1
hsa04520__44 47	3.1212447180773e-07	DOWN	-5.11650837250223	1.15676899906652e-06	Adherens junction: ACTB TJP1
hsa05160__7	3.17461227253484e-07	UP	5.11330788769875	1.17423158663248e-06	Hepatitis C: IRF3
hsa04612__39	3.22886028254549e-07	UP	5.11010740289527	1.19195058367446e-06	Antigen processing and presentation: PSME3
hsa04360__40 142	3.24714101626163e-07	UP	5.10904057462744	1.19634862148149e-06	Axon guidance: UNC5D PTPN11
hsa04921__67	3.43553034560211e-07	UP	5.09837229194916	1.26328014078011e-06	Oxytocin signaling pathway: RYR1
hsa04014__103	3.63444888529346e-07	DOWN	-5.08770400927088	1.33381434677078e-06	Ras signaling pathway: KSR2
hsa05205__109	3.67554528187169e-07	DOWN	-5.08557035273523	1.34626697556275e-06	Proteoglycans in cancer: SMAD2
hsa04360__125	3.80154318780224e-07	UP	5.07916938312826	1.38970810308957e-06	Axon guidance: ENAH*
hsa04066__51	3.84446121709833e-07	UP	5.0770357265926	1.40266847124811e-06	HIF-1 signaling pathway: TFRC
hsa04630__1	3.88784664010166e-07	UP	5.07490207005695	1.41028259396738e-06	Jak-STAT signaling pathway: MYC
hsa04726__41	3.88784664010166e-07	DOWN	-5.07490207005695	1.41028259396738e-06	Serotonergic synapse: HTR3C
hsa04742__57	3.88784664010166e-07	DOWN	-5.07490207005695	1.41028259396738e-06	Taste transduction: HTR3C
hsa04390__17 51	3.90971615059879e-07	DOWN	-5.07383524178912	1.41276089364906e-06	Hippo signaling pathway: YWHAQ YAP1
hsa05132__8	3.90971615059879e-07	DOWN	-5.07383524178912	1.41276089364906e-06	Salmonella infection: TJP1
hsa04261__52	3.97603927787696e-07	DOWN	-5.07063475698564	1.4339688681633e-06	Adrenergic signaling in cardiomyocytes: MAPK14
hsa05200__201	4.11195754762834e-07	UP	5.06423378737867	1.48014717088001e-06	Pathways in cancer: PDGFB
hsa04370__14	4.2523534392065e-07	UP	5.0578328177717	1.52775757404761e-06	VEGF signaling pathway: PTGS2
hsa04670__2	4.57258572937268e-07	UP	5.04396405028994	1.63967339417772e-06	Leukocyte transendothelial migration: MMP2
hsa04910__46	5.46305959646248e-07	DOWN	-5.00982554571945	1.95525504414343e-06	Insulin signaling pathway: FBP1
hsa04261__39	5.55463180680993e-07	DOWN	-5.00662506091597	1.98048447153621e-06	Adrenergic signaling in cardiomyocytes: SCN1B
hsa05010__47	5.55463180680993e-07	DOWN	-5.00662506091597	1.98048447153621e-06	Alzheimer's disease: C00533
hsa04020__18	5.83826648211984e-07	UP	4.99702360650552	2.06983070186852e-06	Calcium signaling pathway: C00002
hsa04020__17	5.83826648211984e-07	UP	4.99702360650552	2.06983070186852e-06	Calcium signaling pathway: C00004
hsa04020__15	5.83826648211984e-07	UP	4.99702360650552	2.06983070186852e-06	Calcium signaling pathway: C13051
hsa04066__26	5.96883193651791e-07	UP	4.99275629343421	2.11213469090719e-06	HIF-1 signaling pathway: C01245
hsa04064__36	6.00189820173454e-07	UP	4.99168946516638	2.11984336862015e-06	NF-kappa B signaling pathway: PLCG1
hsa04340__32	6.13593770680582e-07	UP	4.98742215209507	2.15906871743224e-06	Hedgehog signaling pathway: PTCH1***
hsa04921__54	6.13593770680582e-07	UP	4.98742215209507	2.15906871743224e-06	Oxytocin signaling pathway: RCAN1
hsa04110__60 10 11 12 13 14 9	6.23835607630274e-07	DOWN	-4.98422166729158	2.1910039378267e-06	Cell cycle: CDC6 ORC3 ORC5 ORC4 ORC2 ORC1 ORC6
hsa03320__30	6.30754825816115e-07	DOWN	-4.98208801075593	2.21117223453075e-06	PPAR signaling pathway: LPL
hsa05223__28	6.37747980070048e-07	UP	4.97995435422027	2.23152412393225e-06	Non-small cell lung cancer: RB1
hsa04520__73	6.44815828267697e-07	DOWN	-4.97782069768462	2.25206122921004e-06	Adherens junction: PARD3
hsa04728__36	6.66475226859053e-07	UP	4.97141972807765	2.32338951997803e-06	Dopaminergic synapse: TH
hsa05200__205	6.70152628275269e-07	UP	4.97035289980982	2.3318829417208e-06	Pathways in cancer: SLC2A1
hsa04924__52	6.81302526700149e-07	DOWN	-4.96715241500634	2.36629842452787e-06	Renin secretion: KCNJ2
hsa04024__108	6.85058724832166e-07	UP	4.96608558673851	2.37495450915063e-06	cAMP signaling pathway: AMH
hsa05219__21	7.15835141285965e-07	UP	4.95755096059589	2.47707961413688e-06	Bladder cancer: RB1
hsa04713__14	7.19774598128717e-07	UP	4.95648413232806	2.48613321669827e-06	Circadian entrainment: PRKCA
hsa05150__69	7.31718695773061e-07	UP	4.95328364752458	2.52275124652767e-06	Staphylococcus aureus infection: FPR2
hsa04014__65	7.39787268343288e-07	DOWN	-4.95114999098892	2.54589794362095e-06	Ras signaling pathway: MLLT4*
hsa05030__73	7.43853630056528e-07	DOWN	-4.95008316272109	2.55521201257078e-06	Cocaine addiction: NFKB1
hsa05132__54	7.68707742427992e-07	UP	4.94368219311413	2.63576979566094e-06	Salmonella infection: IL1B
hsa04211__29	7.90028798339599e-07	DOWN	-4.93834805177499	2.70394191635721e-06	Longevity regulating pathway - mammal: EIF4E
hsa05166__62 63	7.98715743680645e-07	UP	4.93621439523933	2.7287034225017e-06	HTLV-I infection: ANAPC10 CDC20
hsa04012__22	8.29850431175554e-07	UP	4.92874659736454	2.829925517566e-06	ErbB signaling pathway: EIF4EBP1
hsa04360__59	8.85962825373434e-07	UP	4.9159446581506	3.01580461753022e-06	Axon guidance: MAPK1*
hsa04630__33	8.9566325590992e-07	DOWN	-4.91381100161495	3.04331149702484e-06	Jak-STAT signaling pathway: RAF1
hsa04210__107	9.00551741972013e-07	DOWN	-4.91274417334712	3.05439841726609e-06	Apoptosis: MCL1
hsa05200__222	9.05465913313882e-07	UP	4.91167734507929	3.06553234435457e-06	Pathways in cancer: CASP9*
hsa05200__202	9.35497618554321e-07	UP	4.90527637547232	3.16151083680498e-06	Pathways in cancer: FIGF*
hsa05211__48	9.56049080052601e-07	DOWN	-4.90100906240101	3.22516377274477e-06	Renal cell carcinoma: JUN
hsa04390__75	9.71747203812748e-07	UP	4.89780857759753	3.27224551248056e-06	Hippo signaling pathway: NKD1
hsa04950__15	9.8769331267279e-07	UP	4.89460809279405	3.31999236943143e-06	Maturity onset diabetes of the young: IAPP
hsa05120__52	1.00934703765093e-06	UP	4.89034077972274	3.38671979240375e-06	Epithelial cell signaling in Helicobacter pylori infection: LYN
hsa05169__60	1.01483145255523e-06	UP	4.88927395145491	3.39905222700764e-06	Epstein-Barr virus infection: NFKB1
hsa04064__142	1.04834524012049e-06	UP	4.88287298184794	3.50505463734236e-06	NF-kappa B signaling pathway: NFKB2*
hsa05200__146 147	1.06548909147002e-06	DOWN	-4.87967249704446	3.54345841216314e-06	Pathways in cancer: RARB RXRA
hsa05222__14 15	1.06548909147002e-06	DOWN	-4.87967249704446	3.54345841216314e-06	Small cell lung cancer: RXRA RARB
hsa05223__29 34	1.06548909147002e-06	DOWN	-4.87967249704446	3.54345841216314e-06	Non-small cell lung cancer: RARB RXRA
hsa05221__41	1.11257364482676e-06	DOWN	-4.87113787090184	3.69350861948673e-06	Acute myeloid leukemia: MAPK1
hsa04920__6	1.13685519563207e-06	DOWN	-4.86687055783052	3.76746192697118e-06	Adipocytokine signaling pathway: PTPN11
hsa04666__27	1.14918640105603e-06	UP	4.86473690129487	3.80162191476106e-06	Fc gamma R-mediated phagocytosis: ARPC5
hsa04064__128	1.186957046407e-06	UP	4.8583359316879	3.91967010579745e-06	NF-kappa B signaling pathway: IL1B*
hsa04360__123	1.22592060300356e-06	UP	4.85193496208093	4.04123651411173e-06	Axon guidance: ENAH
hsa04068__55	1.23917974429054e-06	DOWN	-4.84980130554528	4.07779113751652e-06	FoxO signaling pathway: ATM
hsa05223__23	1.25257678568622e-06	DOWN	-4.84766764900962	4.11467094458811e-06	Non-small cell lung cancer: CASP9*
hsa04550__60	1.29360910150861e-06	DOWN	-4.84126667940266	4.24204450564516e-06	Signaling pathways regulating pluripotency of stem cells: MAPK14
hsa04920__26	1.33593271749226e-06	DOWN	-4.83486570979569	4.37320135220899e-06	Adipocytokine signaling pathway: NPY
hsa04024__12	1.34311490830153e-06	UP	4.83379888152786	4.38906593512794e-06	cAMP signaling pathway: SLC9A1
hsa04932__138	1.35759086033498e-06	DOWN	-4.83166522499221	4.42866879612746e-06	Non-alcoholic fatty liver disease (NAFLD): CEBPA
hsa05214__35	1.4710454374934e-06	UP	4.81566280097479	4.79045819246118e-06	Glioma: E2F1
hsa04151__2	1.47892476909152e-06	DOWN	-4.81459597270696	4.80778484623349e-06	PI3K-Akt signaling pathway: EIF4E
hsa05212__34	1.51893399667375e-06	UP	4.80926183136782	4.92932120854918e-06	Pancreatic cancer: E2F1
hsa04728__74	1.63657289330123e-06	DOWN	-4.79432623561823	5.30193183881553e-06	Dopaminergic synapse: GRIN2A
hsa04710__23	1.68067158770958e-06	UP	4.78899209427909	5.43542497987314e-06	Circadian rhythm: BHLHE41
hsa04932__56	1.69862894993519e-06	UP	4.78685843774344	5.48406150674951e-06	Non-alcoholic fatty liver disease (NAFLD): CASP7
hsa04071__59 60	1.71677063898925e-06	DOWN	-4.78472478120778	5.53312526699966e-06	Sphingolipid signaling pathway: TP53 BCL2
hsa04670__14	1.73509846349286e-06	UP	4.78259112467213	5.58261988510801e-06	Leukocyte transendothelial migration: SIPA1
hsa04360__19	1.79121708959758e-06	UP	4.77619015506516	5.75332805359634e-06	Axon guidance: CDC42
hsa04340__52	2.02293339993403e-06	UP	4.75165310490512	6.48650487794545e-06	Hedgehog signaling pathway: BCL2*
hsa04921__11	2.09899423508533e-06	UP	4.74418530703032	6.71892703190005e-06	Oxytocin signaling pathway: PRKACA
hsa05211__41	2.15499716716366e-06	UP	4.73885116569118	6.88646203588524e-06	Renal cell carcinoma: PDGFB*
hsa05142__21	2.21243360138964e-06	DOWN	-4.73351702435205	7.05800125129225e-06	Chagas disease (American trypanosomiasis): TICAM1
hsa04024__101	2.3074012864978e-06	UP	4.72498239820942	7.34848647004978e-06	cAMP signaling pathway: HCN4
hsa05222__35	2.39369815977435e-06	UP	4.71751460033463	7.61042105281896e-06	Small cell lung cancer: NOS2
hsa04210__99	2.53559925175196e-06	UP	4.70577948938852	8.04795776020596e-06	Apoptosis: BID**
hsa04933__25	2.54889241160866e-06	UP	4.70471266112069	8.07650732110062e-06	AGE-RAGE signaling pathway in diabetic complications: IL1A
hsa04024__3	2.79992276949973e-06	UP	4.68550975229979	8.85699475402354e-06	cAMP signaling pathway: RYR2
hsa04024__34	2.96483194582647e-06	UP	4.67377464135369	9.34717990974487e-06	cAMP signaling pathway: ATP2B1
hsa04340__40	2.96483194582647e-06	UP	4.67377464135369	9.34717990974487e-06	Hedgehog signaling pathway: SUFU
hsa04723__73	2.99579991879988e-06	DOWN	-4.67164098481803	9.41322415957354e-06	Retrograde endocannabinoid signaling: MAPK14*
hsa04723__68	2.99579991879988e-06	DOWN	-4.67164098481803	9.41322415957354e-06	Retrograde endocannabinoid signaling: MAPK14
hsa04064__4	3.0745834066508e-06	UP	4.66630684347889	9.6446447764555e-06	NF-kappa B signaling pathway: BIRC2
hsa04064__129	3.22142877741086e-06	UP	4.65670538906844	1.00884411212583e-05	NF-kappa B signaling pathway: PTGS2
hsa04360__31	3.42771641023963e-06	UP	4.64390344985451	1.07166042177043e-05	Axon guidance: CDC42*
hsa04151__36	3.55383911996844e-06	DOWN	-4.63643565197971	1.10924646286058e-05	PI3K-Akt signaling pathway: PCK1
hsa04151__5	3.66547481546542e-06	DOWN	-4.63003468237275	1.14219356190042e-05	PI3K-Akt signaling pathway: EIF4B
hsa03320__58	3.70342815840413e-06	DOWN	-4.62790102583709	1.1521095214638e-05	PPAR signaling pathway: CYP8B1
hsa04722__34	3.81956192344274e-06	UP	4.62150005623012	1.1862738601899e-05	Neurotrophin signaling pathway: GSK3B
hsa04270__10 3 71	3.83925384688241e-06	DOWN	-4.6204332279623	1.19042210862905e-05	Vascular smooth muscle contraction: ACTA2 MYL9 MYH11
hsa05164__70	4.36439452687638e-06	UP	4.5937625212666	1.34879890065801e-05	Influenza A: RNASEL
hsa05168__83	4.36439452687638e-06	UP	4.5937625212666	1.34879890065801e-05	Herpes simplex infection: RNASEL
hsa04261__8 38	4.50030842299737e-06	DOWN	-4.58736155165963	1.38851880571627e-05	Adrenergic signaling in cardiomyocytes: ATP2A2 PLN
hsa04210__105	4.52335138809951e-06	DOWN	-4.58629472339181	1.39334053413754e-05	Apoptosis: ACTB
hsa05120__53	4.54650736064418e-06	UP	4.58522789512398	1.39818123251234e-05	Epithelial cell signaling in Helicobacter pylori infection: GIT1
hsa04950__18	4.68784606851106e-06	UP	4.57882692551701	1.43929130110005e-05	Maturity onset diabetes of the young: SLC2A2
hsa04015__17	4.78439975583369e-06	UP	4.5745596124457	1.46415100019731e-05	Rap1 signaling pathway: ACTB
hsa04914__39	4.78439975583369e-06	DOWN	-4.5745596124457	1.46415100019731e-05	Progesterone-mediated oocyte maturation: PIK3R5
hsa04024__93	4.95796953879585e-06	UP	4.56709181457091	1.51480077453616e-05	cAMP signaling pathway: ORAI1
hsa05200__209	4.98325218070082e-06	UP	4.56602498630308	1.52005370901572e-05	Pathways in cancer: FIGF**
hsa04010__118	5.03418836380545e-06	UP	4.56389132976742	1.53310209653005e-05	MAPK signaling pathway: JUN
hsa05221__13	5.16371934769437e-06	DOWN	-4.55855718842828	1.57000463662099e-05	Acute myeloid leukemia: NFKB1
hsa05205__319	5.43241958764056e-06	UP	4.54788890575001	1.64903334493968e-05	Proteoglycans in cancer: KDR
hsa04015__100 101 48	5.48774264777822e-06	UP	4.54575524921435	1.66314007018956e-05	Rap1 signaling pathway: PRKCI PARD6A PARD3
hsa04919__21 53	5.57173966594377e-06	DOWN	-4.54255476441087	1.6858774287131e-05	Thyroid hormone signaling pathway: THRA C02465
hsa04015__63	5.62841993336282e-06	DOWN	-4.54042110787521	1.69756036192436e-05	Rap1 signaling pathway: GNAI1
hsa04066__5	5.62841993336282e-06	UP	4.54042110787521	1.69756036192436e-05	HIF-1 signaling pathway: VEGFA
hsa04024__21	6.25786662881855e-06	UP	4.51801771425083	1.88438003133815e-05	cAMP signaling pathway: AKT3
hsa04151__109	6.35310904305763e-06	UP	4.51481722944734	1.90999870270485e-05	PI3K-Akt signaling pathway: RXRA
hsa04931__67	6.38514637957958e-06	DOWN	-4.51375040117951	1.91046534562132e-05	Insulin resistance: IKBKB**
hsa05214__23	6.38516358195949e-06	UP	4.51375040117951	1.91046534562132e-05	Glioma: MAPK1
hsa05214__56	6.38516358195949e-06	UP	4.51375040117951	1.91046534562132e-05	Glioma: MAPK1*
hsa04068__53	6.44973749725151e-06	DOWN	-4.51161674464386	1.92061121352387e-05	FoxO signaling pathway: SOD2
hsa04621__30 32	6.44973749725151e-06	DOWN	-4.51161674464386	1.92061121352387e-05	NOD-like receptor signaling pathway: PYCARD CASP1
hsa04919__103	6.44973749725151e-06	DOWN	-4.51161674464386	1.92061121352387e-05	Thyroid hormone signaling pathway: CCND1
hsa04370__37	6.48225829643082e-06	DOWN	-4.51054991637603	1.92724103465087e-05	VEGF signaling pathway: CASP9
hsa04014__70	6.68070217758851e-06	UP	4.50414894676906	1.9831025895243e-05	Ras signaling pathway: RIN1*
hsa05014__51	7.0244188814535e-06	UP	4.49348066409079	2.08184275682194e-05	Amyotrophic lateral sclerosis (ALS): DERL1
hsa04071__11	7.20255746422096e-06	UP	4.48814652275165	2.12792538919358e-05	Sphingolipid signaling pathway: PRKCA
hsa04933__58	7.20255746422096e-06	DOWN	-4.48814652275165	2.12792538919358e-05	AGE-RAGE signaling pathway in diabetic complications: CCL2
hsa05164__99	7.31150581773544e-06	DOWN	-4.48494603794816	2.15672204576529e-05	Influenza A: FDPS
hsa04064__131	7.34817085869113e-06	UP	4.48387920968034	2.16413997546718e-05	NF-kappa B signaling pathway: CCL4L1
hsa04014__43	7.49659692103889e-06	DOWN	-4.47961189660902	2.2043983747468e-05	Ras signaling pathway: ELK1
hsa05110__51	7.57187743741747e-06	UP	4.47747824007337	2.21958876680019e-05	Vibrio cholerae infection: PDIA4
hsa04064__96	7.57188078509272e-06	UP	4.47747824007337	2.21958876680019e-05	NF-kappa B signaling pathway: BCL2A1
hsa04650__15	7.609793273037e-06	UP	4.47641141180554	2.22722765732656e-05	Natural killer cell mediated cytotoxicity: TNF
hsa04010__62	7.88030814992939e-06	DOWN	-4.46894361393075	2.30281477662789e-05	MAPK signaling pathway: MEF2C
hsa05133__24	7.99903601139642e-06	DOWN	-4.46574312912726	2.33388022754874e-05	Pertussis: NFKB1
hsa05031__10	8.03899057418598e-06	DOWN	-4.46467630085944	2.33827605091261e-05	Amphetamine addiction: CACNA1C
hsa05031__53	8.03899057418598e-06	DOWN	-4.46467630085944	2.33827605091261e-05	Amphetamine addiction: CACNA1C*
hsa04550__47	8.83537096568002e-06	DOWN	-4.44440656377071	2.56198488341246e-05	Signaling pathways regulating pluripotency of stem cells: CTNNB1*
hsa04950__5	8.83537096568002e-06	UP	4.44440656377071	2.56198488341246e-05	Maturity onset diabetes of the young: GCK
hsa05211__27	8.96781169362134e-06	UP	4.44120607896722	2.59638184473259e-05	Renal cell carcinoma: VEGFA*
hsa04915__28	9.28425686092134e-06	UP	4.43373828109243	2.68386440641095e-05	Estrogen signaling pathway: KCNJ3
hsa04920__16	9.37661151820077e-06	DOWN	-4.43160462455677	2.70639831685088e-05	Adipocytokine signaling pathway: POMC
hsa04930__9	9.9986144622766e-06	DOWN	-4.41773585707501	2.88150254211928e-05	Type II diabetes mellitus: C00238
hsa04010__87	1.0349736101146e-05	UP	4.41026805920022	2.97357096850968e-05	MAPK signaling pathway: STK3
hsa04932__55	1.0349736101146e-05	UP	4.41026805920022	2.97357096850968e-05	Non-alcoholic fatty liver disease (NAFLD): CASP3
hsa05321__122	1.07125684441267e-05	DOWN	-4.40280026132542	3.07311696282658e-05	Inflammatory bowel disease (IBD): IL4**
hsa04810__31	1.09791365570124e-05	UP	4.39746611998628	3.14478621808327e-05	Regulation of actin cytoskeleton: MSN
hsa04015__67	1.11969389355356e-05	UP	4.39319880691497	3.20229045051316e-05	Rap1 signaling pathway: AKT3
hsa04620__48	1.14749959433297e-05	UP	4.38786466557583	3.2718539267855e-05	Toll-like receptor signaling pathway: CD80
hsa04660__34	1.14749959433297e-05	DOWN	-4.38786466557583	3.2718539267855e-05	T cell receptor signaling pathway: FOS
hsa04611__7	1.15313927449777e-05	UP	4.386797837308	3.28295257088077e-05	Platelet activation: ITPR1
hsa05160__12 13 14	1.17021749848822e-05	UP	4.38359735250452	3.32653355470405e-05	Hepatitis C: IKBKG CHUK IKBKB
hsa04012__24	1.18173681611612e-05	UP	4.38146369596886	3.35420464876465e-05	ErbB signaling pathway: CDKN1A
hsa04976__59	1.22291268515674e-05	DOWN	-4.37399589809407	3.46584153153773e-05	Bile secretion: ABCB4
hsa05221__35	1.24705278532701e-05	UP	4.36972858502276	3.52893401149013e-05	Acute myeloid leukemia: EIF4EBP1
hsa04151__97	1.26545555900771e-05	UP	4.36652810021928	3.57562555695561e-05	PI3K-Akt signaling pathway: MCL1
hsa04950__21	1.27164719235706e-05	UP	4.36546127195145	3.58772533699538e-05	Maturity onset diabetes of the young: PKLR
hsa04010__78	1.28411728493354e-05	DOWN	-4.36332761541579	3.61747582967035e-05	MAPK signaling pathway: MAP3K4
hsa04064__50	1.34169089186588e-05	UP	4.35372616100534	3.77400776319759e-05	NF-kappa B signaling pathway: NFKBIA*
hsa04151__63	1.36142335993507e-05	DOWN	-4.35052567620186	3.82378848029596e-05	PI3K-Akt signaling pathway: CASP9
hsa04152__58	1.39492736868484e-05	UP	4.34519153486272	3.91204257575943e-05	AMPK signaling pathway: SCD
hsa04662__10	1.4431565463972e-05	UP	4.33772373698792	4.04126848089468e-05	B cell receptor signaling pathway: GSK3B
hsa04115__50	1.45722579126873e-05	DOWN	-4.33559008045227	4.07459413957433e-05	p53 signaling pathway: RCHY1
hsa04919__18	1.48575764294669e-05	UP	4.33132276738096	4.1482000164886e-05	Thyroid hormone signaling pathway: STAT1
hsa04971__56	1.50022255846889e-05	UP	4.3291891108453	4.18237119786801e-05	Gastric acid secretion: CAMK2A
hsa04922__78	1.60530164570728e-05	DOWN	-4.31425351509571	4.468684136717e-05	Glucagon signaling pathway: ACACA
hsa04270__24	1.62087381835415e-05	DOWN	-4.31211985856006	4.49870296113359e-05	Vascular smooth muscle contraction: ACTA2
hsa05223__21	1.62087381835415e-05	DOWN	-4.31211985856006	4.49870296113359e-05	Non-small cell lung cancer: FOXO3*
hsa04919__49	1.65244031485328e-05	DOWN	-4.30785254548874	4.57955066609042e-05	Thyroid hormone signaling pathway: ACTB
hsa04723__7	1.70912723922006e-05	UP	4.30038474761395	4.72967611560307e-05	Retrograde endocannabinoid signaling: ITPR1
hsa04728__54	1.71737348192084e-05	UP	4.29931791934612	4.74550701842539e-05	Dopaminergic synapse: CAMK2A
hsa04919__30	1.73397984603362e-05	DOWN	-4.29718426281047	4.78435848854209e-05	Thyroid hormone signaling pathway: MYH6
hsa04210__4	1.75073915018646e-05	DOWN	-4.29505060627481	4.82351739472193e-05	Apoptosis: DFFA
hsa03320__65	1.76765272591599e-05	DOWN	-4.29291694973916	4.86298604977474e-05	PPAR signaling pathway: ME1
hsa04650__36	1.8634955368217e-05	UP	4.28118183879305	5.11916390890055e-05	Natural killer cell mediated cytotoxicity: CASP3
hsa04068__40	1.87244982633528e-05	DOWN	-4.28011501052522	5.1362528812905e-05	FoxO signaling pathway: CCND1
hsa04068__60	1.89048150750487e-05	UP	4.27798135398957	5.17815561603739e-05	FoxO signaling pathway: RAG1
hsa04151__51	1.94557421848205e-05	UP	4.2715803843826	5.32130124676532e-05	PI3K-Akt signaling pathway: NOS3
hsa05152__78	1.95490372315767e-05	UP	4.27051355611477	5.33904665089136e-05	Tuberculosis: IL1A
hsa04360__81	1.97369070417244e-05	DOWN	-4.26837989957912	5.38253241384618e-05	Axon guidance: FYN*
hsa04340__26	2.04080829199691e-05	DOWN	-4.26091210170432	5.55750547922057e-05	Hedgehog signaling pathway: PTCH1**
hsa05321__46	2.1201747305224e-05	UP	4.2523774755617	5.76527976650013e-05	Inflammatory bowel disease (IBD): IFNG*
hsa04976__37	2.1302954279954e-05	DOWN	-4.25131064729387	5.78442934855977e-05	Bile secretion: ABCB11
hsa04064__115	2.16095148458628e-05	UP	4.24811016249039	5.85920323165602e-05	NF-kappa B signaling pathway: XIAP
hsa04210__51	2.19202281165727e-05	DOWN	-4.2449096776869	5.92634656561729e-05	Apoptosis: LMNA
hsa05100__33	2.19202281165727e-05	UP	4.2449096776869	5.92634656561729e-05	Bacterial invasion of epithelial cells: DNM1
hsa04024__115	2.22351909295819e-05	UP	4.24170919288342	6.00286260871902e-05	cAMP signaling pathway: F2R
hsa05321__123	2.24475540541726e-05	DOWN	-4.23957553634776	6.05149986625399e-05	Inflammatory bowel disease (IBD): IL5*
hsa03320__43	2.39890568259771e-05	UP	4.22463994059817	6.45779910831102e-05	PPAR signaling pathway: ILK
hsa05160__56	2.45636093567209e-05	DOWN	-4.21930579925904	6.60300743652054e-05	Hepatitis C: MAPK1
hsa04910__42	2.46800800875888e-05	DOWN	-4.21823897099121	6.61538808624527e-05	Insulin signaling pathway: PCK1
hsa05219__19	2.46800800875888e-05	DOWN	-4.21823897099121	6.61538808624527e-05	Bladder cancer: TP53
hsa04350__10	2.62428196910861e-05	DOWN	-4.20437020350945	7.02425330477933e-05	TGF-beta signaling pathway: SMAD4
hsa04210__106	2.64914076426561e-05	DOWN	-4.20223654697379	7.07065531697288e-05	Apoptosis: TUBA1B
hsa04918__14	2.64914387607712e-05	DOWN	-4.20223654697379	7.07065531697288e-05	Thyroid hormone synthesis: DUOX2
hsa04015__30	2.95163512102695e-05	UP	4.17769949681375	7.86684027292146e-05	Rap1 signaling pathway: ITGAL
hsa05200__173	2.97943611934303e-05	UP	4.17556584027809	7.91847308096967e-05	Pathways in cancer: CCNA1
hsa05221__16	2.97943611934303e-05	UP	4.17556584027809	7.91847308096967e-05	Acute myeloid leukemia: CCNA1
hsa04014__44	2.99342977278713e-05	DOWN	-4.17449901201027	7.94442732071612e-05	Ras signaling pathway: ETS1
hsa05160__8	3.05003153150071e-05	UP	4.17023169893896	8.08322884018312e-05	Hepatitis C: NFKB1
hsa04664__25	3.06434007835035e-05	DOWN	-4.16916487067113	8.10971127777507e-05	Fc epsilon RI signaling pathway: MAPK14
hsa05134__72	3.09314876447282e-05	DOWN	-4.16703121413547	8.17443956180651e-05	Legionellosis: IL12A
hsa04014__27	3.27147939504498e-05	UP	4.15422927492154	8.63358115630549e-05	Ras signaling pathway: ABL1
hsa04066__55	3.33306304637963e-05	UP	4.14996196185023	8.78376642937914e-05	HIF-1 signaling pathway: ANGPT1
hsa04919__28	3.364266285287e-05	DOWN	-4.14782830531457	8.85358032220487e-05	Thyroid hormone signaling pathway: RCAN1
hsa04722__85	3.39574686378469e-05	DOWN	-4.14569464877892	8.9239277720999e-05	Neurotrophin signaling pathway: BAX
hsa04810__29	3.4595493394156e-05	UP	4.14142733570761	9.07890112955574e-05	Regulation of actin cytoskeleton: ACTN4
hsa04610__44	3.47567694317024e-05	DOWN	-4.14036050743978	9.10850345358003e-05	Complement and coagulation cascades: C3
hsa05205__183	3.74363197376104e-05	UP	4.12329125515453	9.79705359149999e-05	Proteoglycans in cancer: VEGFA*
hsa04970__12	3.81360517412773e-05	UP	4.11902394208322	9.96629224226147e-05	Salivary secretion: BEST2
hsa04530__5 11 31	3.88485381472685e-05	DOWN	-4.11475662901191	0.000101383893303774	Tight junction: IGSF5 TJP1 MLLT4
hsa04923__66	3.93910415945039e-05	DOWN	-4.11155614420843	0.000102657097303846	Regulation of lipolysis in adipocytes: LIPE
hsa04913__45	3.99407300616011e-05	UP	4.10835565940494	0.000103945473387463	Ovarian steroidogenesis: ACOT2
hsa04921__53	4.08730876486869e-05	UP	4.1030215180658	0.000106224801786836	Oxytocin signaling pathway: RGS2
hsa05160__71	4.26036012618745e-05	DOWN	-4.09342006365535	0.000110569291120252	Hepatitis C: MAPK8
hsa05031__101	4.31957252127023e-05	DOWN	-4.09021957885187	0.000111951403689197	Amphetamine addiction: FOS*
hsa04012__35	4.37956503982061e-05	UP	4.08701909404839	0.000113193985004442	ErbB signaling pathway: CBLC
hsa04713__61	4.37956503982061e-05	DOWN	-4.08701909404839	0.000113193985004442	Circadian entrainment: FOS
hsa05212__12	4.5434328075901e-05	DOWN	-4.07848446790576	0.000117267997877223	Pancreatic cancer: CASP9
hsa05152__15	4.60636923374023e-05	DOWN	-4.07528398310228	0.000118729324968421	Tuberculosis: CTSD
hsa04151__24	4.75645127627507e-05	DOWN	-4.06781618522748	0.000122429752713984	PI3K-Akt signaling pathway: MYC
hsa05134__6	4.77826631744428e-05	UP	4.06674935695966	0.000122823015191215	Legionellosis: IL1B
hsa03320__39	4.80017266737466e-05	UP	4.06568252869183	0.000123049537159576	PPAR signaling pathway: MMP1
hsa04917__33	4.80017619680517e-05	DOWN	-4.06568252869183	0.000123049537159576	Prolactin signaling pathway: CSN2
hsa04330__12	4.86647874389998e-05	DOWN	-4.06248204388835	0.000124579203811827	Notch signaling pathway: HES1
hsa04510__24 69	4.91116177174313e-05	UP	4.06034838735269	0.000125552013185107	Focal adhesion: ZYX ACTB
hsa04662__27	5.1875353779185e-05	DOWN	-4.04754644813876	0.000132437214335718	B cell receptor signaling pathway: NFATC1
hsa05161__97	5.23500708386155e-05	DOWN	-4.0454127916031	0.000133467819682169	Hepatitis B: BCL2
hsa04933__62	5.35549386591728e-05	UP	4.04007865026396	0.000136354647344967	AGE-RAGE signaling pathway in diabetic complications: AGER**
hsa04668__102	5.4537702703463e-05	UP	4.03581133719265	0.000138481545107847	TNF signaling pathway: AKT3
hsa05200__200	5.4537702703463e-05	UP	4.03581133719265	0.000138481545107847	Pathways in cancer: FIGF
hsa04071__69	5.50354685184563e-05	UP	4.03367768065699	0.000139556876310633	Sphingolipid signaling pathway: RAC1
hsa05161__188	5.55375362614368e-05	UP	4.03154402412134	0.000140640203012453	Hepatitis B: IFNB1
hsa04022__39	5.6043940806298e-05	UP	4.02941036758568	0.000141731581123868	cGMP-PKG signaling pathway: KCNJ8
hsa03320__57	5.73291569017655e-05	DOWN	-4.02407622624654	0.000144592598413983	PPAR signaling pathway: APOC3
hsa05221__29	5.73291569017655e-05	DOWN	-4.02407622624654	0.000144592598413983	Acute myeloid leukemia: RPS6KB1
hsa04210__52	5.86422545554686e-05	DOWN	-4.01874208490741	0.00014770616127309	Apoptosis: PARP2
hsa05164__20	5.89082695560117e-05	DOWN	-4.01767525663958	0.000148177561573957	Influenza A: ATF2
hsa04014__66	5.9983800460129e-05	UP	4.01340794356827	0.000150681231369762	Ras signaling pathway: RAF1*
hsa05152__6	6.53514368747666e-05	UP	3.99313820647954	0.000163945727486898	Tuberculosis: IL10
hsa05031__98	6.6837763948986e-05	DOWN	-3.9878040651404	0.00016745087794686	Amphetamine addiction: FOS
hsa04064__130	6.86635876936694e-05	UP	3.98140309553343	0.000171796113550472	NF-kappa B signaling pathway: TNF*
hsa04024__9 95	7.21341380443151e-05	DOWN	-3.96966798458733	0.000180239422054878	cAMP signaling pathway: ATP1B4 FXYD1
hsa04068__68	7.40964472869821e-05	DOWN	-3.96326701498036	0.000184896712419973	FoxO signaling pathway: ATG12
hsa04713__60	7.64496067150759e-05	DOWN	-3.95579921710556	0.000190515664479612	Circadian entrainment: PER1
hsa05200__194	7.74795840406361e-05	DOWN	-3.95259873230208	0.000192826673393848	Pathways in cancer: BCL2
hsa04010__117	7.78258155712255e-05	UP	3.95153190403425	0.000193432152722662	MAPK signaling pathway: JUND
hsa04950__13	7.8173509560338e-05	UP	3.95046507576642	0.000194039662435766	Maturity onset diabetes of the young: INS
hsa04742__27	7.99341194200044e-05	UP	3.94513093442729	0.000198148034815552	Taste transduction: CALHM1
hsa04660__43	8.46887740049489e-05	DOWN	-3.93126216694552	0.000209657715883134	T cell receptor signaling pathway: RHOA
hsa04211__51	8.58233363326327e-05	UP	3.92806168214204	0.00021218690653818	Longevity regulating pathway - mammal: NFKB1
hsa04022__19	8.62047046455627e-05	UP	3.92699485387421	0.00021284972408543	cGMP-PKG signaling pathway: CNGB1
hsa05162__23	8.73584398286482e-05	UP	3.92379436907073	0.000215415365404239	Measles: IRF3
hsa04024__107 64	8.77462493205066e-05	UP	3.9227275408029	0.000216088076635953	cAMP signaling pathway: NFKBIA NFKB1
hsa04068__43	8.81356849261092e-05	DOWN	-3.92166071253507	0.000216763026146805	FoxO signaling pathway: CDKN1A
hsa04722__53	8.93138122737316e-05	DOWN	-3.91846022773159	0.000219087014702796	Neurotrophin signaling pathway: JUN
hsa04728__71 72	8.93138122737316e-05	UP	3.91846022773159	0.000219087014702796	Dopaminergic synapse: CLOCK ARNTL
hsa04666__40	9.01074785331867e-05	UP	3.91632657119593	0.000220745700344013	Fc gamma R-mediated phagocytosis: PLA2G6
hsa05166__114 112 113	9.1714839716784e-05	DOWN	-3.91205925812462	0.000224390864359163	HTLV-I infection: DLG1 CTNNB1 APC2
hsa04810__26 80	9.21208908115282e-05	UP	3.91099242985679	0.000225091227353526	Regulation of actin cytoskeleton: PFN3 ACTB
hsa04071__66	9.71278221644299e-05	UP	3.89819049064286	0.000236709698893598	Sphingolipid signaling pathway: C01245
hsa05223__8	9.71278221644299e-05	DOWN	-3.89819049064286	0.000236709698893598	Non-small cell lung cancer: CASP9
hsa04024__91	0.000100166061369246	UP	3.89072269276807	0.000243797965431106	cAMP signaling pathway: GRIA1
hsa04340__14	0.000101495437697637	DOWN	-3.88752220796458	0.000246714007029574	Hedgehog signaling pathway: PTCH1
hsa05166__132 136	0.000104204307863889	UP	3.88112123835762	0.000252971439891794	HTLV-I infection: CREBBP TP53
hsa04924__31	0.000106047438897564	DOWN	-3.8768539252863	0.000257113726049707	Renin secretion: C02135
hsa04917__65	0.000106513675662936	UP	3.87578709701848	0.00025791133578693	Prolactin signaling pathway: CYP17A1
hsa04660__26	0.000107450876089494	UP	3.87365344048282	0.000259845812319381	T cell receptor signaling pathway: GRB2
hsa04728__70 73	0.000108871277446286	DOWN	-3.87045295567934	0.000262942326891481	Dopaminergic synapse: KIF5A GRIA1
hsa04115__3	0.000110309380735953	DOWN	-3.86725247087585	0.000266073589734088	p53 signaling pathway: GADD45G
hsa04630__27	0.000111278052159046	UP	3.8651188143402	0.000267722740085593	Jak-STAT signaling pathway: PIM1
hsa04660__35	0.000111278052159046	DOWN	-3.8651188143402	0.000267722740085593	T cell receptor signaling pathway: NFATC1
hsa04350__12	0.00011523356318894	DOWN	-3.85658418819758	0.00027688473814836	TGF-beta signaling pathway: ACVR2A
hsa05152__9	0.000117260691637949	DOWN	-3.85231687512626	0.000281395708285703	Tuberculosis: TCIRG1
hsa04915__40	0.000119321414809718	UP	3.84804956205495	0.000285975686769719	Estrogen signaling pathway: CREB3**
hsa04360__29	0.000120364536194929	DOWN	-3.8459159055193	0.000288108233771046	Axon guidance: RASA1
hsa04919__40	0.000120889315423036	DOWN	-3.84484907725147	0.000288996213333186	Thyroid hormone signaling pathway: RCAN2
hsa05321__83	0.000121416251307872	UP	3.84378224898364	0.000289887085397067	Inflammatory bowel disease (IBD): IL2
hsa04068__46	0.000132420803282369	DOWN	-3.82244568362709	0.000315759758080674	FoxO signaling pathway: PLK4
hsa05160__54	0.00013531524142206	UP	3.81711154228795	0.000322252647188911	Hepatitis C: IRF1
hsa05205__45 46	0.000139467718261588	UP	3.80964374441315	0.000331721319763955	Proteoglycans in cancer: PAK1 FLNA
hsa04360__35	0.000140070636016001	DOWN	-3.80857691614532	0.000332734165706785	Axon guidance: ROCK1*
hsa04014__64	0.000142506943712145	UP	3.80430960307401	0.000337667777093468	Ras signaling pathway: PIK3R5*
hsa04066__52	0.000142506943712145	UP	3.80430960307401	0.000337667777093468	HIF-1 signaling pathway: FLT1
hsa04750__7	0.000144359884862568	UP	3.80110911827053	0.000341197765605993	Inflammatory mediator regulation of TRP channels: TRPV1
hsa04750__58	0.000144359884862568	UP	3.80110911827053	0.000341197765605993	Inflammatory mediator regulation of TRP channels: TRPV1**
hsa05010__49	0.000147499771341008	DOWN	-3.79577497693139	0.000348180992901701	Alzheimer's disease: EIF2AK3
hsa04066__53	0.000150703441499617	DOWN	-3.79044083559225	0.000355297072243136	HIF-1 signaling pathway: EGF*
hsa05132__68	0.000155298769341993	UP	3.78297303771746	0.000365672164904266	Salmonella infection: NOS2
hsa04910__14	0.000162787333036313	DOWN	-3.77123792677135	0.000382825280069128	Insulin signaling pathway: C00369
hsa05134__9	0.000163484702109034	UP	3.77017109850352	0.000383984694078594	Legionellosis: CASP7
hsa04742__54	0.000164884103546798	DOWN	-3.76803744196787	0.000386305773771115	Taste transduction: P2RX2*
hsa04742__40	0.000164884103546798	DOWN	-3.76803744196787	0.000386305773771115	Taste transduction: P2RX2
hsa04151__25	0.000167728299403471	DOWN	-3.76377012889656	0.000392480043062418	PI3K-Akt signaling pathway: CDKN1B
hsa03320__66	0.00017354777320697	DOWN	-3.75523550275393	0.000405592370467534	PPAR signaling pathway: UCP1
hsa05169__83	0.000174288416126188	UP	3.75416867448611	0.000406817309193921	Epstein-Barr virus infection: GSK3B
hsa04668__120	0.000175778628556316	UP	3.75203501795045	0.000409278863763716	TNF signaling pathway: DNM1L
hsa05142__84	0.000175778628556316	UP	3.75203501795045	0.000409278863763716	Chagas disease (American trypanosomiasis): NFKB1*
hsa04152__62	0.000192166250862207	UP	3.72963162432607	0.000446881665061988	AMPK signaling pathway: EIF4EBP1
hsa04724__52	0.000203019391909246	UP	3.7157628568443	0.000471537005435691	Glutamatergic synapse: CACNA1A
hsa05213__13	0.000203877668599796	DOWN	-3.71469602857648	0.000472945850986439	Endometrial cancer: CASP9
hsa05010__50	0.000217167827780784	DOWN	-3.69869360455906	0.000503154560296045	Alzheimer's disease: ERN1
hsa04810__30	0.000218082154463626	UP	3.69762677629123	0.00050465069979945	Regulation of actin cytoskeleton: VCL*
hsa04152__49	0.000225527966391793	DOWN	-3.68909215014861	0.000521238682472545	AMPK signaling pathway: GYS1
hsa04010__63	0.000226475293478669	DOWN	-3.68802532188078	0.000522785106199533	MAPK signaling pathway: MAX
hsa04064__2	0.000231268212961767	UP	3.68269118054164	0.000533193830865228	NF-kappa B signaling pathway: BCL2L1
hsa04066__88	0.000233211903005639	DOWN	-3.68055752400599	0.000537016134494603	HIF-1 signaling pathway: BCL2
hsa04024__43	0.000235170914791853	UP	3.67842386747033	0.000540864319331569	cAMP signaling pathway: MAPK8
hsa04340__33	0.000237145360110155	UP	3.67629021093467	0.000544073420814385	Hedgehog signaling pathway: HHIP*
hsa04919__26	0.000237145360110155	DOWN	-3.67629021093467	0.000544073420814385	Thyroid hormone signaling pathway: THRB
hsa04390__5	0.000239135351489922	UP	3.67415655439902	0.000547969909084834	Hippo signaling pathway: SAV1
hsa04540__12	0.000253510114325786	UP	3.65922095864943	0.000580201589303474	Gap junction: C00025
hsa04923__31	0.000259915592600062	UP	3.65281998904246	0.000594137954374107	Regulation of lipolysis in adipocytes: PRKACA*
hsa04550__25	0.000264269829995933	DOWN	-3.64855267597115	0.000603357242481601	Signaling pathways regulating pluripotency of stem cells: MAPK1
hsa04932__95	0.000268692381096261	UP	3.64428536289984	0.00061270993213577	Non-alcoholic fatty liver disease (NAFLD): IL1A
hsa04310__14	0.000273184235878798	UP	3.64001804982853	0.000622197792989407	Wnt signaling pathway: PRKCA
hsa04014__30	0.000278898041834664	DOWN	-3.63468390848939	0.000634442397829702	Ras signaling pathway: C01245
hsa05321__75	0.000290663202418722	UP	3.62401562581111	0.000660406478046892	Inflammatory bowel disease (IBD): IL10
hsa04115__2	0.00029428241650125	UP	3.62081514100763	0.000667822053871798	p53 signaling pathway: IGFBP3
hsa04664__23	0.000305394948203434	DOWN	-3.61121368659718	0.000692203989956879	Fc epsilon RI signaling pathway: AKT3
hsa04064__54	0.000313020301893158	UP	3.60481271699021	0.000708632707538849	NF-kappa B signaling pathway: CCL13
hsa05134__70	0.000315601447469386	DOWN	-3.60267906045455	0.000713616269308034	Legionellosis: IL6
hsa04550__101	0.000324793215447843	DOWN	-3.59521126257976	0.000733517369983771	Signaling pathways regulating pluripotency of stem cells: ESRRB
hsa04919__42	0.000326126595878616	UP	3.59414443431193	0.000735644506189579	Thyroid hormone signaling pathway: SLC2A1
hsa04151__26	0.000331511516121562	DOWN	-3.58987712124062	0.000746894650830233	PI3K-Akt signaling pathway: RBL2
hsa04261__20	0.000339745105463775	DOWN	-3.58347615163365	0.000763613699959847	Adrenergic signaling in cardiomyocytes: ATP1B4
hsa05010__51	0.000339745105463775	DOWN	-3.58347615163365	0.000763613699959847	Alzheimer's disease: ATF6
hsa04970__21	0.000341135831888285	UP	3.58240932336583	0.000765823450559244	Salivary secretion: ITPR1
hsa04066__30	0.000352454910281824	UP	3.5738746972232	0.000790289709331203	HIF-1 signaling pathway: PDK1
hsa04022__63	0.000358245274881432	UP	3.56960738415189	0.000802315699049118	cGMP-PKG signaling pathway: C00575
hsa04920__43	0.00036412450365921	DOWN	-3.56534007108058	0.000814511836161495	Adipocytokine signaling pathway: C00162
hsa05210__53	0.000367097833709545	DOWN	-3.56320641454493	0.00082018647983381	Colorectal cancer: CCND1*
hsa05166__34 35 36	0.000370092581489467	DOWN	-3.56107275800927	0.000825895440164738	HTLV-I infection: MYC TRRAP KAT5
hsa04723__9	0.000373112717015793	UP	3.55893910147361	0.00082967904765997	Retrograde endocannabinoid signaling: PRKCA
hsa04725__20	0.000373112717015793	UP	3.55893910147361	0.00082967904765997	Cholinergic synapse: PRKCA
hsa04726__18	0.000373112717015793	UP	3.55893910147361	0.00082967904765997	Serotonergic synapse: PRKCA
hsa05133__60	0.000376154590031422	UP	3.55680544493796	0.000835454461783737	Pertussis: C5
hsa04662__16	0.000377684204824069	UP	3.55573861667013	0.000837861417785626	B cell receptor signaling pathway: VAV3
hsa05016__48	0.000390132090268838	UP	3.54720399052751	0.000863437217450113	Huntington's disease: HIP1
hsa05016__46	0.000390132090268838	UP	3.54720399052751	0.000863437217450113	Huntington's disease: HTT**
hsa03320__55	0.000394898099550967	DOWN	-3.54400350572402	0.000872957093007372	PPAR signaling pathway: SCD
hsa05140__16	0.000396498820842213	UP	3.5429366774562	0.000875465669051137	Leishmaniasis: STAT1
hsa04380__20	0.000402962525338341	UP	3.53866936438489	0.000888693175012609	Osteoclast differentiation: MAP2K1
hsa04971__52 53	0.000416186303337657	UP	3.53013473824226	0.000916780848735588	Gastric acid secretion: EZR ACTB
hsa04550__36	0.000419554998393206	DOWN	-3.52800108170661	0.000923119252904958	Signaling pathways regulating pluripotency of stem cells: AKT3*
hsa04261__36	0.000426368914617091	DOWN	-3.5237337686353	0.000937014257971362	Adrenergic signaling in cardiomyocytes: MAPK1
hsa05231__21	0.000429814490284494	UP	3.52160011209964	0.000943482975752995	Choline metabolism in cancer: PCYT1A
hsa03320__33	0.000460169310351496	DOWN	-3.50346403154657	0.00100776006311243	PPAR signaling pathway: CYP7A1
hsa04261__34	0.000460169310351496	DOWN	-3.50346403154657	0.00100776006311243	Adrenergic signaling in cardiomyocytes: AKT3
hsa05200__184	0.000462015753907257	UP	3.50239720327874	0.00101062584585767	Pathways in cancer: GLI1
hsa04620__86	0.000463869108468687	DOWN	-3.50133037501091	0.00101232294403329	Toll-like receptor signaling pathway: IL12A
hsa04725__50	0.000463869108468687	DOWN	-3.50133037501091	0.00101232294403329	Cholinergic synapse: BCL2
hsa04621__21 30	0.000475135702068613	DOWN	-3.49492940540394	0.00103570763826789	NOD-like receptor signaling pathway: NLRP3 PYCARD
hsa04540__22	0.000488598763630479	DOWN	-3.48746160752915	0.00106382048303786	Gap junction: C00547
hsa05218__8	0.000504428710794373	UP	3.47892698138653	0.00109701568007248	Melanoma: CDK4
hsa05210__16	0.000508459259801713	DOWN	-3.47679332485087	0.00110450283140742	Colorectal cancer: MAPK8
hsa04360__3	0.000514561409059492	DOWN	-3.47359284004739	0.00111646753767065	Axon guidance: GNAI1
hsa04710__11	0.000522803827756676	DOWN	-3.46932552697608	0.0011330431284369	Circadian rhythm: CRY1
hsa04921__58	0.000524883572693177	DOWN	-3.46825869870825	0.00113623989987382	Oxytocin signaling pathway: MEF2C
hsa05205__233 234	0.000533279896651769	DOWN	-3.46399138563694	0.00115308737147143	Proteoglycans in cancer: ITGA2 C00925
hsa04961__5	0.000537524833689623	DOWN	-3.46185772910128	0.0011609300718423	Endocrine and other factor-regulated calcium reabsorption: TRPV5
hsa05164__34	0.000552631313813501	UP	3.45438993122649	0.00119218626711317	Influenza A: IL1B
hsa04722__84	0.000563662766050314	DOWN	-3.44905578988735	0.00121458983647768	Neurotrophin signaling pathway: NFKB1*
hsa05166__120	0.000577171149616203	UP	3.44265482028038	0.00124227329911666	HTLV-I infection: E2F1
hsa04068__41	0.000581740517469626	DOWN	-3.44052116374473	0.00125067555185976	FoxO signaling pathway: CDKN2B
hsa04810__48	0.000588657755212859	UP	3.43732067894124	0.0012641004823371	Regulation of actin cytoskeleton: IQGAP2
hsa05231__18	0.000617099531113957	DOWN	-3.42451873972731	0.00132366440520905	Choline metabolism in cancer: CHKA
hsa05016__52	0.000621962346806424	UP	3.42238508319165	0.00133257383084295	Huntington's disease: CASP3
hsa04970__27	0.000624407102370218	UP	3.42131825492383	0.0013362880926579	Salivary secretion: PRKCA
hsa05231__39	0.000641772339198538	UP	3.41385045704903	0.00137188876604557	Choline metabolism in cancer: EIF4EBP1
hsa05321__92	0.000675219498553502	DOWN	-3.39998168956727	0.00144174708838867	Inflammatory bowel disease (IBD): IL17F
hsa04668__20	0.000683164834623739	UP	3.39678120476378	0.00145705644070148	TNF signaling pathway: IKBKG
hsa05020__59	0.000693893840491918	UP	3.39251389169247	0.00147826136766929	Prion diseases: CCL5
hsa04921__34 35	0.000696600452965154	DOWN	-3.39144706342465	0.0014823468302622	Oxytocin signaling pathway: MYL9 ACTB
hsa04670__86	0.000702036732827955	UP	3.38931340688899	0.00149222513685942	Leukocyte transendothelial migration: ACTB
hsa04550__67	0.000727027766955682	DOWN	-3.37971195247854	0.00154359906679065	Signaling pathways regulating pluripotency of stem cells: MYC*
hsa05020__62	0.000732690746788206	UP	3.37757829594288	0.00155386671920433	Prion diseases: NOTCH1
hsa04014__33	0.000735537861865347	DOWN	-3.37651146767506	0.00155639148923985	Ras signaling pathway: BCL2L1
hsa04919__101	0.000735537861865347	DOWN	-3.37651146767506	0.00155639148923985	Thyroid hormone signaling pathway: NOTCH1
hsa04010__79	0.000749927245123558	DOWN	-3.37117732633592	0.0015814964013324	MAPK signaling pathway: HSPB1
hsa04360__111	0.000749927245123558	UP	3.37117732633592	0.0015814964013324	Axon guidance: RHOA***
hsa05213__27	0.000749927245123558	DOWN	-3.37117732633592	0.0015814964013324	Endometrial cancer: ELK1
hsa04919__25	0.000755755853196675	UP	3.36904366980026	0.00159200139927865	Thyroid hormone signaling pathway: MTOR
hsa05200__187	0.000758685905943027	UP	3.36797684153243	0.00159638389391596	Pathways in cancer: WNT16*
hsa04110__96 97	0.000776488883695331	UP	3.36157587192547	0.00163019286308774	Cell cycle: TFDP1 E2F4
hsa05205__81	0.000776488883695331	UP	3.36157587192547	0.00163019286308774	Proteoglycans in cancer: CTTN
hsa04728__68	0.000779493482076763	DOWN	-3.36050904365764	0.00163467438931053	Dopaminergic synapse: CACNA1C
hsa04066__64	0.000782508869816858	UP	3.35944221538981	0.00163916852439897	HIF-1 signaling pathway: LTBR
hsa04020__22	0.000785532465858053	DOWN	-3.35837538712198	0.00164366982555377	Calcium signaling pathway: C00575
hsa04310__22	0.000810138738874937	DOWN	-3.34984076097936	0.00169327106823805	Wnt signaling pathway: ROCK2
hsa05205__121	0.000822706943516671	UP	3.34557344790805	0.00171762927429758	Proteoglycans in cancer: PLAUR
hsa04923__43	0.000829058657210243	DOWN	-3.34343979137239	0.00172896916414878	Regulation of lipolysis in adipocytes: C00219
hsa04620__39	0.00083225154543631	DOWN	-3.34237296310457	0.00173370360740003	Toll-like receptor signaling pathway: IL6
hsa04064__132	0.000858208304394539	UP	3.33383833696194	0.00178579557470359	NF-kappa B signaling pathway: VCAM1
hsa05169__93	0.000878166359907334	UP	3.32743736735498	0.00182530375029412	Epstein-Barr virus infection: PLCG1
hsa05200__183	0.000901994275532768	UP	3.31996956948018	0.00187275938533267	Pathways in cancer: BMP2
hsa05200__53	0.000915877870914161	DOWN	-3.31570225640887	0.00189948622455597	Pathways in cancer: BCL2L1
hsa04072__36	0.000922893686231982	UP	3.31356859987321	0.00191192639077166	Phospholipase D signaling pathway: MTOR
hsa04932__31 133	0.000966042391664714	DOWN	-3.30076666065928	0.00199691815918462	Non-alcoholic fatty liver disease (NAFLD): PPARA RXRA
hsa04962__22	0.000966045027514007	DOWN	-3.30076666065928	0.00199691815918462	Vasopressin-regulated water reabsorption: ARHGDIA
hsa04152__53	0.000969724042001684	UP	3.29969983239145	0.00200232030211117	AMPK signaling pathway: G6PC
hsa05200__65	0.000973416028123758	UP	3.29863300412363	0.00200773734011475	Pathways in cancer: STK4
hsa04152__87	0.000995842682437083	DOWN	-3.29223203451666	0.00205174166699482	AMPK signaling pathway: CD36
hsa04910__9	0.00103820513973882	UP	3.28049692357055	0.00213667848583706	Insulin signaling pathway: ELK1
hsa05321__55	0.00107409914333227	UP	3.2708954691601	0.00220813160866667	Inflammatory bowel disease (IBD): IL4*
hsa05150__35	0.00108631187271469	UP	3.26769498435662	0.00223079782385891	Staphylococcus aureus infection: FCAR
hsa04630__35	0.00109453289582515	DOWN	-3.26556132782096	0.00224522632233129	Jak-STAT signaling pathway: MTOR
hsa05212__10	0.00111952777009767	DOWN	-3.259160358214	0.00229399419848804	Pancreatic cancer: BCL2L1
hsa04724__33 70 69	0.00112374453265923	UP	3.25809352994617	0.0023001263364561	Glutamatergic synapse: ITPR1 HOMER3 HOMER3
hsa04210__72	0.00113222214353392	UP	3.25595987341051	0.00231495691806337	Apoptosis: BCL2A1
hsa04261__15 17	0.00114075884452997	DOWN	-3.25382621687486	0.00232987594442589	Adrenergic signaling in cardiomyocytes: ACTC1 MYH6
hsa04650__110 111	0.00114935500837969	UP	3.2516925603392	0.00234488388788864	Natural killer cell mediated cytotoxicity: ITGAL ITGB2
hsa05210__40	0.00117991528142157	DOWN	-3.24422476246441	0.00240462127309234	Colorectal cancer: CASP9
hsa04921__56	0.00119771366027541	DOWN	-3.2399574493931	0.00243561035460767	Oxytocin signaling pathway: JUN
hsa05150__13	0.00119771366027541	UP	3.2399574493931	0.00243561035460767	Staphylococcus aureus infection: C5AR1
hsa04110__48	0.00120220184424729	UP	3.23889062112527	0.00243945709000072	Cell cycle: RB1*
hsa04115__1	0.00120220184424729	UP	3.23889062112527	0.00243945709000072	p53 signaling pathway: SIAH1
hsa04261__37	0.00123405677245506	DOWN	-3.23142282325047	0.00250139447189111	Adrenergic signaling in cardiomyocytes: CREB3
hsa05150__66	0.00124794603396865	UP	3.22822233844699	0.00252682176489988	Staphylococcus aureus infection: IL10
hsa04151__37	0.0012526077705707	DOWN	-3.22715551017916	0.00253353067911986	PI3K-Akt signaling pathway: G6PC
hsa05200__49	0.00127141596370905	DOWN	-3.22288819710785	0.00256880709226806	Pathways in cancer: CASP9
hsa04210__83	0.00127615857512461	DOWN	-3.22182136884002	0.00257561972358662	Apoptosis: TP53*
hsa05161__214	0.00130011754426257	DOWN	-3.21648722750088	0.00262115972711306	Hepatitis B: CDKN1B
hsa05134__59	0.00130495887780491	UP	3.21542039923306	0.00262810046237452	Legionellosis: HSPA1A
hsa04610__17	0.0013146914954369	UP	3.2132867426974	0.00264486650955667	Complement and coagulation cascades: PLG
hsa05161__227	0.00136942873645034	UP	3.20155163175129	0.00275203913988256	Hepatitis B: MYD88*
hsa04015__82	0.00138471771905317	UP	3.19835114694781	0.0027797912330138	Rap1 signaling pathway: ITGA2B
hsa05164__47	0.00142626122669462	UP	3.18981652080519	0.00286013323901728	Influenza A: CIITA
hsa04012__65	0.0014743692810468	DOWN	-3.18021506639474	0.00295345402887732	ErbB signaling pathway: MYC
hsa04917__37	0.00151281560688094	UP	3.17274726851994	0.00302724230599498	Prolactin signaling pathway: TNFSF11
hsa04668__141	0.00152396869147504	UP	3.17061361198429	0.00304631613966127	TNF signaling pathway: JUN*
hsa05220__25	0.00153519746967117	DOWN	-3.16847995544863	0.00306550057971533	Chronic myeloid leukemia: BCL2L1*
hsa04910__32	0.00154084038822814	DOWN	-3.1674131271808	0.00307350221813236	Insulin signaling pathway: EIF4E
hsa04210__31 32 33	0.00154650240371994	UP	3.16634629891298	0.00308152493805914	Apoptosis: TRAF2 RIPK1 TRADD
hsa04664__30	0.00156934260058464	UP	3.16207898584166	0.00312372324840946	Fc epsilon RI signaling pathway: PRKCA
hsa04550__22	0.00162780864981336	UP	3.15141070316339	0.00323666926243313	Signaling pathways regulating pluripotency of stem cells: SMAD2
hsa04921__80	0.00163376418514701	DOWN	-3.15034387489556	0.00324165037369719	Oxytocin signaling pathway: KCNJ2
hsa05140__62	0.00163376418514701	UP	3.15034387489556	0.00324165037369719	Leishmaniasis: C00584
hsa05211__43	0.0016457354547223	UP	3.1482102183599	0.00326195877576288	Renal cell carcinoma: RAP1A
hsa04931__87	0.00166384376848763	DOWN	-3.14500973355642	0.0032943755964049	Insulin resistance: C00031*
hsa05219__10	0.00168213524152382	DOWN	-3.14180924875294	0.00332708644086659	Bladder cancer: EGFR
hsa05212__29	0.00168827338837927	UP	3.14074242048511	0.00333571576946861	Pancreatic cancer: VEGFA
hsa04913__40	0.00182202933309377	DOWN	-3.11833902686072	0.00359621125723025	Ovarian steroidogenesis: HSD17B1
hsa04066__49	0.00183526311036381	UP	3.11620537032507	0.00361473730018197	HIF-1 signaling pathway: EPO
hsa05200__218	0.00183526311036381	UP	3.11620537032507	0.00361473730018197	Pathways in cancer: CSF3R*
hsa05160__77	0.00188227991244912	UP	3.10873757245027	0.00370345963925853	Hepatitis C: NFKB1*
hsa04950__1	0.00190276450756455	UP	3.10553708764679	0.00373984781350815	Maturity onset diabetes of the young: HNF1B
hsa05133__30	0.00191653797008168	UP	3.10340343111113	0.00376298311994094	Pertussis: NOS2
hsa05161__48	0.00197964895730574	UP	3.09380197670068	0.00388283965634394	Hepatitis B: STAT1
hsa04660__40 41	0.00198677780062591	DOWN	-3.09273514843286	0.00389275858954753	T cell receptor signaling pathway: LAT GRAP2
hsa04920__9	0.00203734318009546	UP	3.08526735055806	0.003987674828541	Adipocytokine signaling pathway: G6PC
hsa04540__1	0.00205936616299777	DOWN	-3.08206686575458	0.00402241427948805	Gap junction: C00681
hsa04310__34	0.00205937335650213	UP	3.08206686575458	0.00402241427948805	Wnt signaling pathway: FOSL1
hsa04261__73	0.00208162187808994	DOWN	-3.07886638095109	0.00406164850356281	Adrenergic signaling in cardiomyocytes: KCNE1
hsa05205__30	0.0021267817070554	DOWN	-3.07246541134413	0.00414545936468579	Proteoglycans in cancer: FLNA
hsa04660__41 46	0.00216509926555449	DOWN	-3.06713127000499	0.00421577359583097	T cell receptor signaling pathway: GRAP2 LCP2
hsa04621__23	0.00219620786375059	UP	3.06286395693368	0.00427191985091859	NOD-like receptor signaling pathway: CASP1
hsa04022__46	0.00222772565391788	UP	3.05859664386237	0.00432874509173908	cGMP-PKG signaling pathway: VASP
hsa04621__44	0.00240009973304788	DOWN	-3.03619325023798	0.00465887127933571	NOD-like receptor signaling pathway: MAPK14
hsa05133__96	0.00245154520961227	UP	3.02979228063101	0.0047538219286496	Pertussis: IL1B
hsa05223__14	0.00251283923469384	DOWN	-3.02232448275622	0.0048676545587523	Non-small cell lung cancer: CCND1
hsa05221__26	0.00253953469109289	UP	3.01912399795274	0.00491430039604895	Acute myeloid leukemia: BAD
hsa05223__37	0.00255747549824705	DOWN	-3.01699034141708	0.0049439264004179	Non-small cell lung cancer: CCND1*
hsa05222__19	0.002630403803953	DOWN	-3.00845571527446	0.00507968011061427	Small cell lung cancer: CASP9
hsa05200__219	0.00270522851420764	DOWN	-2.99992108913184	0.00521881352997553	Pathways in cancer: MYC**
hsa05110__50	0.00271471260536755	UP	2.99885426086401	0.00523173844665192	Vibrio cholerae infection: ACTB
hsa05169__118	0.00272423611010348	DOWN	-2.99778743259618	0.00524471275705372	Epstein-Barr virus infection: MDM2
hsa04930__26	0.00274336565114227	UP	2.99565377606052	0.00527613516734527	Type II diabetes mellitus: INS*
hsa04520__17	0.00281128942270586	UP	2.98818597818573	0.00540124010763223	Adherens junction: SNAI1
hsa04340__46	0.00288074567922023	DOWN	-2.98071818031093	0.00552903077758407	Hedgehog signaling pathway: PRKACA
hsa05020__52	0.00290087607231914	UP	2.97858452377528	0.00556198585702823	Prion diseases: FYN
hsa05166__33	0.00292529890878098	UP	2.85163195990377	0.00560309546340415	HTLV-I infection: HLA-A
hsa05030__80 81	0.00293131248561825	UP	2.9753840389718	0.00560889629376446	Cocaine addiction: GRIN3A DLG4
hsa04670__76	0.00297234772348423	UP	2.97111672590048	0.00568162906655835	Leukocyte transendothelial migration: CDC42
hsa04668__111	0.00302437861968061	UP	2.96578258456135	0.00577521079916652	TNF signaling pathway: BAG4
hsa04911__31	0.00306660002919964	UP	2.96151527149003	0.00584988980189453	Insulin secretion: CAMK2A
hsa05212__27	0.00307723903258561	DOWN	-2.96044844322221	0.00586423138157035	Pancreatic cancer: BCL2L1*
hsa05014__2	0.00314178296891816	DOWN	-2.95404747361524	0.00597511153704172	Amyotrophic lateral sclerosis (ALS): SLC1A2
hsa05161__126	0.00314178296891816	UP	2.95404747361524	0.00597511153704172	Hepatitis B: MYC*
hsa04925__3	0.00320755873438606	DOWN	-2.94764650400827	0.00609403727190234	Aldosterone synthesis and secretion: ITPR1
hsa04668__38	0.00322976130968324	UP	2.94551284747262	0.00613002171807557	TNF signaling pathway: CEBPB
hsa03320__29	0.00326332782377695	DOWN	-2.94231236266913	0.00618124292427106	PPAR signaling pathway: OLR1
hsa05211__49	0.00326332782377695	UP	2.94231236266913	0.00618124292427106	Renal cell carcinoma: TGFA*
hsa04727__49	0.00328588173914053	UP	2.94017870613348	0.00621769565744718	GABAergic synapse: GABRR3
hsa04152__61	0.00333141607986249	UP	2.93591139306217	0.00629751590951874	AMPK signaling pathway: RPS6KB1
hsa04062__8 41	0.00338914188049184	UP	2.93057725172303	0.00640019858637606	Chemokine signaling pathway: PXN PTK2B
hsa05200__216	0.00340079575424888	DOWN	-2.9295104234552	0.00641575825525466	Pathways in cancer: IL6
hsa04151__32	0.00345961422226996	DOWN	-2.92417628211606	0.00652017565059704	PI3K-Akt signaling pathway: BCL2L1
hsa04670__54	0.00348339974707567	UP	2.9220426255804	0.00655842497470459	Leukocyte transendothelial migration: RAC1*
hsa03320__44	0.00355565198681371	DOWN	-2.91564165597344	0.00668775784106403	PPAR signaling pathway: FABP1
hsa05216__12	0.00359178909545127	DOWN	-2.91244117116995	0.00674897171035294	Thyroid cancer: CDH1
hsa04668__36	0.00360457478509891	UP	2.91137434290213	0.00676622979140945	TNF signaling pathway: CREB3
hsa05211__22	0.00362926507082984	UP	2.90924068636647	0.00680577751306314	Renal cell carcinoma: TGFA
hsa04210__50	0.00367910761190087	DOWN	-2.90497337329516	0.00689236610444838	Apoptosis: SPTA1
hsa05215__34	0.0036916651066492	UP	2.90390654502733	0.00690900272449587	Prostate cancer: BAD
hsa04630__7	0.00371689707027519	UP	2.90177288849168	0.00694930307964885	Jak-STAT signaling pathway: BCL2
hsa04010__131	0.00380644840122185	UP	2.89430509061688	0.00710965859432987	MAPK signaling pathway: MYC
hsa04210__84	0.00385849652066397	DOWN	-2.89003777754557	0.00719971694372155	Apoptosis: FAS**
hsa04630__34	0.00396453704120768	DOWN	-2.88150315140295	0.00739024315518773	Jak-STAT signaling pathway: AOX1
hsa05162__101	0.00412856508042372	DOWN	-2.86870121218901	0.00768837838068995	Measles: CDKN1B
hsa05145__23	0.00417052288794253	UP	2.86550072738553	0.00775882426380596	Toxoplasmosis: CIITA
hsa05220__22	0.00428430838091189	DOWN	-2.85696610124291	0.0079626265556216	Chronic myeloid leukemia: CDKN1B
hsa04913__35	0.004371486955548	DOWN	-2.85056513163594	0.00811662449552835	Ovarian steroidogenesis: HSD17B2
hsa04152__30	0.00441567650518698	UP	2.84736464683246	0.00819057863104277	AMPK signaling pathway: ACACA
hsa05162__20	0.00443049607567994	UP	2.84629781856463	0.008209962649115	Measles: NFKB1
hsa05162__25 70	0.00444536070588852	UP	2.8452309902968	0.00822939188804387	Measles: IFNAR1 GNB2L1
hsa04310__16	0.00446027051585004	UP	2.84416416202897	0.00824886643630141	Wnt signaling pathway: CAMK2A
hsa04742__37	0.00453547170645941	DOWN	-2.83883002068983	0.00837969649600514	Taste transduction: P2RY4
hsa05220__4	0.00462729488267619	DOWN	-2.83242905108287	0.00854094998482177	Chronic myeloid leukemia: PTPN11
hsa04620__87	0.00468942166555594	DOWN	-2.82816173801156	0.00864712787986223	Toll-like receptor signaling pathway: CCL4L1
hsa04068__49	0.00470507089148458	DOWN	-2.82709490974373	0.00866747863245052	FoxO signaling pathway: BCL2L11
hsa04919__89	0.00476814165227348	DOWN	-2.82282759667242	0.00877506186544748	Thyroid hormone signaling pathway: CASP9
hsa04012__40	0.00484805569286513	UP	2.81749345533328	0.00891340180713657	ErbB signaling pathway: ELK1*
hsa04370__16	0.00496197148257604	UP	2.81002565745848	0.00911392416007856	VEGF signaling pathway: HSPB1
hsa04014__54	0.00502814778318052	DOWN	-2.80575834438717	0.00922645477011346	Ras signaling pathway: RHOA
hsa05205__140	0.00517997102149677	UP	2.79615688997672	0.00949577126769993	Proteoglycans in cancer: MAPK1***
hsa04310__31	0.00519709346405994	UP	2.79509006170889	0.00951787389763023	Wnt signaling pathway: MMP7
hsa04722__35	0.00537115172668976	DOWN	-2.78442177903062	0.0098270633831062	Neurotrophin signaling pathway: FOXO3
hsa05150__48	0.00547809647778033	UP	2.77802080942365	0.0100129798460596	Staphylococcus aureus infection: C3AR1
hsa03320__32	0.00558695955364725	DOWN	-2.77161983981668	0.0102020379021411	PPAR signaling pathway: FABP3
hsa05200__196	0.00564211978310714	UP	2.7684193550132	0.0102927602645226	Pathways in cancer: TRAF1
hsa04390__94	0.00584860203565422	UP	2.75668424406709	0.0106487628149169	Hippo signaling pathway: GLI2
hsa04933__27	0.00584860203565422	UP	2.75668424406709	0.0106487628149169	AGE-RAGE signaling pathway in diabetic complications: TNF
hsa04724__68	0.00596407735663892	UP	2.75028327446012	0.010838009045575	Glutamatergic synapse: MAPK1
hsa04919__45	0.00596407735663892	UP	2.75028327446012	0.010838009045575	Thyroid hormone signaling pathway: SLC9A1
hsa04064__97	0.00606187179265857	UP	2.74494913312099	0.0109838544825511	NF-kappa B signaling pathway: PLCG2
hsa04310__13	0.00606187179265857	UP	2.74494913312099	0.0109838544825511	Wnt signaling pathway: NFATC1
hsa04976__38	0.00606187179265857	UP	2.74494913312099	0.0109838544825511	Bile secretion: ABCC2
hsa04014__61	0.00618113036912642	UP	2.73854816351402	0.0111891560342857	Ras signaling pathway: RAP1A
hsa04360__145	0.00620121092976387	UP	2.73748133524619	0.0112147019605643	Axon guidance: ABLIM3
hsa04014__79	0.00646765598544587	DOWN	-2.72361256776443	0.0116853130737046	Ras signaling pathway: RAC1**
hsa04010__68	0.00648857224005824	DOWN	-2.7225457394966	0.0117118417282127	MAPK signaling pathway: ATF2
hsa04024__44 67	0.00659406898763168	UP	2.71721159815746	0.0118908403337427	cAMP signaling pathway: CREB3 CREBBP
hsa05152__13	0.00672269944952232	DOWN	-2.7108106285505	0.0121111718750263	Tuberculosis: LAMP1
hsa05032__37	0.00674435579502433	UP	2.70974380028267	0.0121385484088608	Morphine addiction: KCNJ3
hsa04390__95	0.00678785669182927	UP	2.70761014374701	0.0122051509320069	Hippo signaling pathway: AFP
hsa04213__52	0.00687561570547701	DOWN	-2.7033428306757	0.0123511299336437	Longevity regulating pathway - multiple species: SOD2
hsa04913__64	0.00689771413269445	UP	2.70227600240787	0.0123789922209483	Ovarian steroidogenesis: PLA2G4B
hsa04062__59	0.00703164977307684	DOWN	-2.69587503280091	0.0126073186294002	Chemokine signaling pathway: FOXO3
hsa04621__42	0.00714504180788321	DOWN	-2.69054089146177	0.0127984113984867	NOD-like receptor signaling pathway: MAPK8
hsa05020__46	0.00730654835175071	UP	2.68307309358697	0.0130752422408948	Prion diseases: PRKACA
hsa04916__10	0.00732988617657142	DOWN	-2.68200626531914	0.0131045253337561	Melanogenesis: CAMK2A
hsa05152__76	0.00742390769978386	UP	2.67773895224783	0.0132600024409638	Tuberculosis: TNF*
hsa05215__35	0.00747132291101542	DOWN	-2.67560529571218	0.0133320187557436	Prostate cancer: CASP9
hsa04022__50	0.00751900952702475	UP	2.67347163917652	0.0134043822592785	cGMP-PKG signaling pathway: ATP2B1
hsa04010__61	0.00754295502886602	DOWN	-2.67240481090869	0.0134343246438287	MAPK signaling pathway: ATF4
hsa04010__58	0.00768806931890534	UP	2.66600384130173	0.0136798127369537	MAPK signaling pathway: CDC25B
hsa04650__119	0.00778619720073421	DOWN	-2.66173652823042	0.0138413098771803	Natural killer cell mediated cytotoxicity: KLRC4-KLRK1
hsa04210__63	0.0080618605754989	DOWN	-2.65000141728431	0.0143178034228378	Apoptosis: FAS*
hsa04920__1	0.00811290967305831	UP	2.64786776074865	0.0143948605058325	Adipocytokine signaling pathway: C00195
hsa05152__98	0.0082938679224201	UP	2.64039996287386	0.0147020545530447	Tuberculosis: IL23A
hsa04152__52	0.00837252080016341	UP	2.63719947807038	0.0148274897111282	AMPK signaling pathway: PCK1
hsa04360__11	0.0085050924882051	UP	2.63186533673124	0.0150480873684909	Axon guidance: NFATC2
hsa04666__23	0.00855864458795002	UP	2.62973168019558	0.015128591891588	Fc gamma R-mediated phagocytosis: RPS6KB1
hsa05152__88 89	0.00858553352030872	UP	2.62866485192775	0.0151618585382144	Tuberculosis: ITGAX ITGB2
hsa04310__32	0.00885860513350392	UP	2.61799656924947	0.0156147458216265	Wnt signaling pathway: PPARD
hsa04921__43	0.00885860513350392	UP	2.61799656924947	0.0156147458216265	Oxytocin signaling pathway: CACNG3
hsa04913__12	0.00902614791187564	DOWN	-2.61159559964251	0.0158951564446245	Ovarian steroidogenesis: HSD3B1
hsa04015__18	0.00919651440944358	UP	2.60519463003554	0.0161800099020079	Rap1 signaling pathway: CDH1
hsa05200__192	0.00922518619069122	UP	2.60412780176771	0.0162152711434133	Pathways in cancer: PTGS2
hsa04664__3 4 5	0.00931165697038828	DOWN	-2.60092731696423	0.0163519658386538	Fc epsilon RI signaling pathway: FCER1G MS4A2 FCER1A
hsa04925__18	0.00936974511858134	DOWN	-2.59879366042857	0.0164386097832067	Aldosterone synthesis and secretion: PDE2A
hsa05223__7	0.00942813224235274	DOWN	-2.59666000389292	0.0165256161225567	Non-small cell lung cancer: FOXO3
hsa04022__48	0.0094574473277199	UP	2.59559317562509	0.0165461299150705	cGMP-PKG signaling pathway: SLC8A2
hsa04213__61	0.0094574473277199	DOWN	-2.59559317562509	0.0165461299150705	Longevity regulating pathway - multiple species: ATG5
hsa04020__42	0.00960524565628609	DOWN	-2.59025903428595	0.0167734726655777	Calcium signaling pathway: MYLK4
hsa04064__55	0.00960524565628609	DOWN	-2.59025903428595	0.0167734726655777	NF-kappa B signaling pathway: CXCL12
hsa05145__13	0.00990703411469624	UP	2.57959075160767	0.0172683832110522	Toxoplasmosis: GNAI1
hsa05162__62	0.00990703411469624	DOWN	-2.57959075160767	0.0172683832110522	Measles: IL12A
hsa04914__42	0.0099992033218359	DOWN	-2.57639026680419	0.017412885117451	Progesterone-mediated oocyte maturation: ARAF
hsa04390__52	0.010123283384051	UP	2.57212295373288	0.0176126384061406	Hippo signaling pathway: ITGB2
hsa04917__56	0.0101545168267767	DOWN	-2.57105612546505	0.0176506356313723	Prolactin signaling pathway: LHCGR
hsa04742__67	0.0104074888864505	DOWN	-2.56252149932243	0.0180736336577083	Taste transduction: PRKACA
hsa04115__16	0.0104395014739518	DOWN	-2.5614546710546	0.0181124868601619	p53 signaling pathway: PPM1D
hsa04064__113	0.0104716016414392	UP	2.56038784278677	0.0181514201884356	NF-kappa B signaling pathway: CFLAR
hsa04014__35	0.0106987721474783	DOWN	-2.55292004491198	0.0185110431538783	Ras signaling pathway: NFKB1
hsa05133__94	0.0106987721474783	DOWN	-2.55292004491198	0.0185110431538783	Pertussis: IL12A
hsa05166__89 90	0.0107315802915299	UP	2.55185321664415	0.0185507261893144	HTLV-I infection: CHUK IKBKG
hsa03320__41	0.0108969664329913	DOWN	-2.54651907530501	0.0188193014040355	PPAR signaling pathway: ANGPTL4
hsa04621__43	0.0110309022809459	DOWN	-2.5422517622337	0.0190156563173371	NOD-like receptor signaling pathway: MAPK1
hsa04710__7	0.0110309022809459	DOWN	-2.5422517622337	0.0190156563173371	Circadian rhythm: PER1
hsa04152__15	0.0112003776519064	DOWN	-2.53691762089456	0.0192901096314686	AMPK signaling pathway: FOXO1
hsa05205__434	0.0113721615038802	UP	2.53158347955542	0.0195680324778305	Proteoglycans in cancer: CASP3
hsa05205__77	0.0114414421467324	DOWN	-2.52944982301977	0.0196513984299498	Proteoglycans in cancer: MIR21
hsa04727__35	0.0114415273455908	DOWN	-2.52944982301977	0.0196513984299498	GABAergic synapse: PRKACA
hsa04910__43	0.0115112684856889	DOWN	-2.52731616648411	0.019753126469963	Insulin signaling pathway: G6PC
hsa04730__7	0.0116165876253902	DOWN	-2.52411568168063	0.0198975097065708	Long-term depression: GNA13
hsa05010__12	0.0116165876253902	UP	2.52411568168063	0.0198975097065708	Alzheimer's disease: CASP3
hsa04650__25	0.0116518835120944	DOWN	-2.5230488534128	0.0199397897260705	Natural killer cell mediated cytotoxicity: SH2D1B
hsa04020__64	0.0119376928328196	UP	2.51451422727018	0.0203917498480618	Calcium signaling pathway: C01330*
hsa04020__12	0.0119376928328196	UP	2.51451422727018	0.0203917498480618	Calcium signaling pathway: C01330
hsa04919__87	0.0124154032618427	UP	2.50064545978841	0.0211885038410558	Thyroid hormone signaling pathway: BAD
hsa05231__34	0.0126415397329072	DOWN	-2.49424449018145	0.0215548576752565	Choline metabolism in cancer: PLD1
hsa04152__57	0.0128713147826202	UP	2.48784352057448	0.0219068844896226	AMPK signaling pathway: ACACA*
hsa05110__52	0.0128713147826202	UP	2.48784352057448	0.0219068844896226	Vibrio cholerae infection: ADCY3
hsa04115__20	0.0129487234906695	UP	2.48570986403882	0.0219987806862279	p53 signaling pathway: RRM2B
hsa05219__27	0.0129487234906695	DOWN	-2.48570986403882	0.0219987806862279	Bladder cancer: RPS6KA5
hsa04310__57	0.0132229069669209	UP	2.47824206616403	0.0224443018887482	Wnt signaling pathway: SIAH1
hsa04210__58	0.0133021821182908	UP	2.47610840962837	0.0225584839352603	Apoptosis: BID*
hsa05152__129	0.0136641427232825	UP	2.46650695521792	0.0231514194563101	Tuberculosis: IFNB1
hsa04810__35 81 80	0.0143716472177523	DOWN	-2.44837087466485	0.0243282208307717	Regulation of actin cytoskeleton: MYL12B MYH9 ACTB
hsa04666__29	0.0144142536667157	UP	2.44730404639702	0.0243783822140043	Fc gamma R-mediated phagocytosis: WAS
hsa04014__62	0.0148464830747106	DOWN	-2.43663576371875	0.0250868180731846	Ras signaling pathway: RASSF5
hsa04020__8	0.0150225475447598	DOWN	-2.43236845064743	0.0253615155764632	Calcium signaling pathway: PDE1A
hsa04012__25	0.0151112675150032	UP	2.43023479411178	0.0254883946684839	ErbB signaling pathway: CDKN1B
hsa04725__61	0.0153350892430651	DOWN	-2.42490065277264	0.0258427198992998	Cholinergic synapse: FOS
hsa04068__39	0.0157453307833187	UP	2.41529919836219	0.0265102836396558	FoxO signaling pathway: CCNB3
hsa05014__5	0.0161180624016586	UP	2.40676457221957	0.0271135534939271	Amyotrophic lateral sclerosis (ALS): TOMM40
hsa04917__71	0.0164026790977255	DOWN	-2.4003636026126	0.0275676511848178	Prolactin signaling pathway: CCND1*
hsa04911__54	0.016498527633225	UP	2.39822994607694	0.0277039619506969	Insulin secretion: RAB3A
hsa04390__58	0.0165466361225835	UP	2.39716311780912	0.0277599368520843	Hippo signaling pathway: SMAD7
hsa05169__79	0.0166432228439222	DOWN	-2.39502946127346	0.0278970702263423	Epstein-Barr virus infection: ATF2
hsa04270__17	0.0167403042924492	UP	2.3928958047378	0.0280347876697969	Vascular smooth muscle contraction: ITPR1
hsa05205__422	0.0169851860748122	UP	2.38756166339867	0.0284195588909813	Proteoglycans in cancer: CD63
hsa04550__9	0.0173835375963736	UP	2.37902703725604	0.0290602020850409	Signaling pathways regulating pluripotency of stem cells: HNF1A
hsa04740__13	0.0174339031146654	DOWN	-2.37796020898822	0.0291184924021834	Olfactory transduction: CNGA3
hsa05142__44	0.0175350181319328	UP	2.37582655245256	0.0292613668471596	Chagas disease (American trypanosomiasis): PLCB1
hsa04916__4	0.0176876546233813	DOWN	-2.37262606764908	0.0294898873445727	Melanogenesis: TYR
hsa04210__73	0.017738791584404	UP	2.37155923938125	0.0295489267616091	Apoptosis: TRAF1
hsa05142__36	0.0178414543164861	UP	2.36942558284559	0.0296936161742049	Chagas disease (American trypanosomiasis): SMAD2
hsa04010__66	0.0181525724472355	DOWN	-2.36302461323863	0.0301579872929757	MAPK signaling pathway: TP53
hsa05212__19	0.0181525724472355	DOWN	-2.36302461323863	0.0301579872929757	Pancreatic cancer: MAPK8
hsa04724__44	0.0184154562992775	DOWN	-2.35769047189949	0.0305677052882884	Glutamatergic synapse: PRKACA*
hsa04270__28	0.0186281566002905	UP	2.35342315882818	0.0308934741853008	Vascular smooth muscle contraction: KCNMB2
hsa04010__134	0.0190600140350414	UP	2.34488853268555	0.031581804560708	MAPK signaling pathway: ATF4*
hsa04210__60	0.0191693365060055	UP	2.3427548761499	0.0317349632553166	Apoptosis: BBC3
hsa04066__60	0.0192242029912466	UP	2.34168804788207	0.0317977794195004	HIF-1 signaling pathway: NOS3
hsa04066__61	0.0196121258926281	DOWN	-2.33422025000727	0.0323824117330827	HIF-1 signaling pathway: HMOX1
hsa04151__100	0.0196121258926281	UP	2.33422025000727	0.0323824117330827	PI3K-Akt signaling pathway: PRKCA
hsa05132__48	0.0200068685422799	UP	2.32675245213248	0.0330051852422686	Salmonella infection: KLC3
hsa05161__195	0.0201209183832412	DOWN	-2.32461879559682	0.0331642154755353	Hepatitis B: IL6
hsa04921__23	0.0201781557684955	UP	2.323551967329	0.033229408141107	Oxytocin signaling pathway: C00219
hsa04550__53 64	0.0205245726643955	UP	2.31715099772203	0.0337702907499117	Signaling pathways regulating pluripotency of stem cells: SMAD1 SMAD4
hsa04350__21	0.0209352708993734	DOWN	-2.30968319984723	0.0344159002798973	TGF-beta signaling pathway: CDKN2B
hsa04261__15 16	0.0209945228894267	DOWN	-2.30861637157941	0.0344831368087699	Adrenergic signaling in cardiomyocytes: ACTC1 TPM1
hsa04261__23	0.0211134653947001	DOWN	-2.30648271504375	0.0346482108966301	Adrenergic signaling in cardiomyocytes: SLC9A1
hsa04932__96	0.0211731564950375	DOWN	-2.30541588677592	0.0347158473422125	Non-alcoholic fatty liver disease (NAFLD): IL6*
hsa04933__28	0.0212329945512318	UP	2.3043490585081	0.0347836065926456	AGE-RAGE signaling pathway in diabetic complications: VCAM1
hsa05142__7	0.021473756195205	UP	2.30008174543678	0.0351168946338256	Chagas disease (American trypanosomiasis): C1QA
hsa05213__11	0.0214738222108918	DOWN	-2.30008174543678	0.0351168946338256	Endometrial cancer: FOXO3
hsa04961__12	0.0220243963466313	UP	2.29048029102633	0.0359859484654958	Endocrine and other factor-regulated calcium reabsorption: SLC8A1
hsa05032__4	0.0222730116773002	UP	2.28621297795502	0.036360546430623	Morphine addiction: ADCY1
hsa03320__62	0.022398206432411	UP	2.28407932141937	0.0365331856653648	PPAR signaling pathway: UBC
hsa05205__318	0.0227139636013135	UP	2.27874518008023	0.0370160777162776	Proteoglycans in cancer: HSPB2
hsa04917__44	0.0230335555343417	DOWN	-2.27341103874109	0.0375043768189151	Prolactin signaling pathway: PRLR**
hsa04213__53	0.0232271794168335	DOWN	-2.27021055393761	0.0377542129102338	Longevity regulating pathway - multiple species: SOD1
hsa04622__9 35	0.0232271794168335	DOWN	-2.27021055393761	0.0377542129102338	RIG-I-like receptor signaling pathway: IRF3 PIN1
hsa04742__47	0.0232920339953537	DOWN	-2.26914372566978	0.0378269074133704	Taste transduction: GABRA1
hsa04668__153	0.0239492738765572	UP	2.2584754429915	0.0388606956943445	TNF signaling pathway: MAPK14*
hsa04726__16	0.0250343171110248	UP	2.24140619070625	0.0405512774582893	Serotonergic synapse: ITPR1
hsa04726__46	0.0250343171110248	UP	2.24140619070625	0.0405512774582893	Serotonergic synapse: ITPR1*
hsa04668__128	0.0253121375267843	UP	2.23713887763494	0.0409307284103508	TNF signaling pathway: CHUK*
hsa05166__53 146	0.0253121375267843	UP	2.23713887763494	0.0409307284103508	HTLV-I infection: CREB1 CRTC2
hsa05211__31	0.0255222501654966	UP	2.23393839283146	0.0412350026319588	Renal cell carcinoma: SOS1
hsa04722__46	0.025663162092538	UP	2.2318047362958	0.0414270460239509	Neurotrophin signaling pathway: ATF4*
hsa04931__124	0.0263778597651404	DOWN	-2.22113645361753	0.0425442047199131	Insulin resistance: FOXO1*
hsa04066__63	0.0265955953022367	UP	2.21793596881404	0.0427852085384441	HIF-1 signaling pathway: TIMP1*
hsa04066__57	0.0265955953022367	UP	2.21793596881404	0.0427852085384441	HIF-1 signaling pathway: TIMP1
hsa05140__21	0.0265955953022367	UP	2.21793596881404	0.0427852085384441	Leishmaniasis: NFKB1
hsa05032__30	0.0266684604004067	DOWN	-2.21686914054621	0.0428291840106288	Morphine addiction: ADORA1
hsa04611__25	0.026668517984266	DOWN	-2.21686914054621	0.0428291840106288	Platelet activation: ORAI1
hsa05169__11	0.0270250626993215	UP	1.95122890185709	0.0433647248608241	Epstein-Barr virus infection: HLA-A
hsa05140__26	0.0271096906195235	DOWN	-2.21046817093925	0.0434634033055329	Leishmaniasis: C00533
hsa04520__7 68	0.0274072930258531	DOWN	-2.20620085786794	0.0439030721189924	Adherens junction: CDH1 CTNNB1
hsa04211__23	0.0274821325449781	DOWN	-2.20513402960011	0.0439480230229904	Longevity regulating pathway - mammal: SOD2
hsa04910__20	0.0274821325449781	UP	2.20513402960011	0.0439480230229904	Insulin signaling pathway: PKLR
hsa04022__44	0.027632340586001	UP	2.20300037306445	0.0441506530281427	cGMP-PKG signaling pathway: BAD
hsa04022__49	0.0282402745519969	UP	2.19446574692183	0.045083666850639	cGMP-PKG signaling pathway: ATP1B4
hsa05200__227	0.0287816366239194	DOWN	-2.18699794904704	0.0459089093517356	Pathways in cancer: FOXO1
hsa04742__8	0.0290949564918696	UP	2.18273063597572	0.0463693157321654	Taste transduction: PLCB2
hsa04022__37 38	0.0291737733756366	DOWN	-2.1816638077079	0.0464555255701874	cGMP-PKG signaling pathway: ATP2A1 PLN
hsa04919__43	0.0292527500479576	DOWN	-2.18059697944007	0.0465418436410774	Thyroid hormone signaling pathway: TBC1D4
hsa04015__96	0.0296503985829651	DOWN	-2.17526283810093	0.0471346014698743	Rap1 signaling pathway: PLCE1
hsa05133__27	0.0297304836949743	UP	2.1741960098331	0.0472219601545703	Pertussis: IRF3
hsa05166__39	0.0302149107457863	UP	2.16779504022613	0.0479508591987605	HTLV-I infection: RRAS2
hsa04662__6	0.030377886569167	UP	2.16566138369048	0.0481282030889248	B cell receptor signaling pathway: NFKB1
hsa04742__4	0.030377886569167	UP	2.16566138369048	0.0481282030889248	Taste transduction: TRPM5
hsa04390__80	0.0305416170235227	UP	2.16352772715482	0.0483468394163431	Hippo signaling pathway: BIRC2
hsa04911__4	0.0310373636549247	DOWN	-2.15712675754786	0.0490902409996663	Insulin secretion: CACNA1C
hsa05205__113	0.0312878163719435	UP	2.15392627274437	0.0494447493379999	Proteoglycans in cancer: TP53
hsa05031__97	0.0315400011445669	DOWN	-2.15072578794089	0.0497595819904628	Amphetamine addiction: ARC
hsa05210__31	0.0315400011445669	DOWN	-2.15072578794089	0.0497595819904628	Colorectal cancer: BCL2
hsa04670__28 41 49	0.0318789580287586	UP	2.14645847486958	0.0502521494429844	Leukocyte transendothelial migration: ACTB CTNNA1 CTNNB1
hsa03320__64	0.0321352207820511	DOWN	-2.14325799006609	0.0506136461437335	PPAR signaling pathway: APOA5
hsa04740__39	0.0328272350613215	UP	2.13472336392347	0.0516602803016944	Olfactory transduction: PRKG1*
hsa05145__29	0.0332661584852104	DOWN	-2.12938922258433	0.052263523942866	Toxoplasmosis: C06314
hsa04360__117	0.0332661919295731	DOWN	-2.12938922258433	0.052263523942866	Axon guidance: CFL1*
hsa04014__26	0.0338891633797048	DOWN	-2.12192142470954	0.0531977760989686	Ras signaling pathway: PRKCA
hsa04010__120	0.0341591892109545	UP	2.11872093990605	0.0535768919260296	MAPK signaling pathway: NFATC1
hsa04072__3	0.034613318789132	DOWN	-2.11338679856692	0.0542438915802994	Phospholipase D signaling pathway: MAPK1
hsa05160__85	0.0347964092851735	UP	2.11125314203126	0.0544853775390341	Hepatitis C: BAD
hsa04390__14	0.0348882642589647	UP	2.11018631376343	0.0545837206849248	Hippo signaling pathway: AREG
hsa04914__23	0.0351650724161112	DOWN	-2.10698582895995	0.0549710241845865	Progesterone-mediated oocyte maturation: PRKACA
hsa05020__48	0.0353506508347553	UP	2.10485217242429	0.0552151894584415	Prion diseases: SOD1
hsa04810__8 79	0.0356305851836587	UP	2.10165168762081	0.0555600577262196	Regulation of actin cytoskeleton: ARPC5 ACTB
hsa04810__8 82	0.0356305851836587	UP	2.10165168762081	0.0555600577262196	Regulation of actin cytoskeleton: ARPC5 ACTB*
hsa04919__44	0.0359124083202124	DOWN	-2.09845120281733	0.0559530806249411	Thyroid hormone signaling pathway: PFKFB2
hsa05133__59	0.0360067707959148	UP	2.0973843745495	0.0560536224735078	Pertussis: C3
hsa04915__21	0.0361961300823392	UP	2.09525071801384	0.0563017619409896	Estrogen signaling pathway: CREB3
hsa04924__49	0.0364817603352135	DOWN	-2.09205023321036	0.0566991130437271	Renin secretion: PDE1A
hsa04620__40	0.0372528467246456	UP	2.08351560706774	0.0578496685914125	Toll-like receptor signaling pathway: CCL5
hsa04014__38	0.037938886134089	DOWN	-2.07604780919294	0.0588177945923707	Ras signaling pathway: MAPK8
hsa04115__37	0.037938886134089	DOWN	-2.07604780919294	0.0588177945923707	p53 signaling pathway: FAS
hsa04623__9	0.0387360603358156	UP	2.06751318305032	0.0600041693083244	Cytosolic DNA-sensing pathway: IKBKE
hsa05145__9	0.0391399557790299	UP	2.06324586997901	0.0605798821324524	Toxoplasmosis: MAPK1
hsa05211__45	0.0394452194303818	UP	2.06004538517552	0.0610021130120884	Renal cell carcinoma: ETS1
hsa04024__60	0.0396498494423451	UP	2.05791172863987	0.0612681472879659	cAMP signaling pathway: PDE3A
hsa04062__22 41	0.0398553797007247	UP	2.05577807210421	0.0615351343119652	Chemokine signaling pathway: CRK PTK2B
hsa04932__14	0.0402691530447379	UP	2.0515107590329	0.0621229380714799	Non-alcoholic fatty liver disease (NAFLD): PKLR
hsa04662__36	0.0407914875243666	UP	2.04617661769376	0.062877116536739	B cell receptor signaling pathway: CD79A
hsa04071__89	0.0410020232683192	UP	2.04404296115811	0.0631498374763702	Sphingolipid signaling pathway: C00533
hsa04723__67	0.041213478982967	UP	2.04190930462245	0.0634235274438944	Retrograde endocannabinoid signaling: PRKACA
hsa04912__15	0.0420685626841563	UP	2.03337467847983	0.0646864396755563	GnRH signaling pathway: CAMK2A
hsa05168__10	0.0422846641467146	DOWN	-2.03124102194417	0.0649655633129	Herpes simplex infection: FOS
hsa04213__13	0.0425017039717857	DOWN	-2.02910736540852	0.0651924096024371	Longevity regulating pathway - multiple species: RPS6KB1*
hsa04921__59	0.0425017039717857	DOWN	-2.02910736540852	0.0651924096024371	Oxytocin signaling pathway: CCND1
hsa04380__16	0.0427196852415973	UP	2.02697370887286	0.0654733185717467	Osteoclast differentiation: NFKB1
hsa05213__12	0.0431584844682264	UP	2.02270639580155	0.0660919252777485	Endometrial cancer: BAD
hsa04360__4	0.0433793086133089	DOWN	-2.02057273926589	0.0663219860735617	Axon guidance: GNAI1*
hsa05200__214	0.0433793086133089	UP	2.02057273926589	0.0663219860735617	Pathways in cancer: CSF3R
hsa04920__5	0.043601086579618	UP	2.01843908273024	0.0666068631569937	Adipocytokine signaling pathway: NFKBIA
hsa05212__8	0.0438238214730604	DOWN	-2.01630542619458	0.0668927380567673	Pancreatic cancer: NFKB1
hsa04668__40	0.0442721744882981	DOWN	-2.01203811312327	0.0675222531359676	TNF signaling pathway: JUN
hsa04015__27	0.0443848656874635	DOWN	-2.01097128485544	0.0676392235415604	Rap1 signaling pathway: RALA
hsa04724__36	0.0446109743521041	UP	2.00883762831979	0.0679287040580256	Glutamatergic synapse: TRPC1
hsa04115__39	0.0448380539779208	UP	2.00670397178413	0.0681639995343958	p53 signaling pathway: BAX
hsa04933__63	0.0448380539779208	DOWN	-2.00670397178413	0.0681639995343958	AGE-RAGE signaling pathway in diabetic complications: SELE
hsa05134__10	0.0450661076962237	UP	2.00457031524848	0.0684553082952339	Legionellosis: NFKB1
hsa05220__21	0.0451805008198351	UP	2.00350348698065	0.0685736357354363	Chronic myeloid leukemia: NFKBIA
hsa04210__119	0.0456405242367714	UP	1.99923617390934	0.0692159362719075	Apoptosis: BCL2*
hsa04530__8	0.0468078770440016	DOWN	-1.98856789123106	0.070929033036838	Tight junction: LLGL2
hsa04110__46	0.0470443376109557	UP	1.9864342346954	0.0712299036027282	Cell cycle: RB1
hsa04722__38	0.0472818022411208	DOWN	-1.98430057815975	0.071531808704562	Neurotrophin signaling pathway: ATF4
hsa04270__46	0.047879877458132	UP	1.97896643682061	0.0723783505581898	Vascular smooth muscle contraction: ITPR1*
hsa05205__189	0.0481208813630209	UP	1.97683278028495	0.072684192991251	Proteoglycans in cancer: IL12B
hsa05212__14	0.0489724358969923	DOWN	-1.96936498241016	0.0739110096790751	Pancreatic cancer: MAPK1
hsa05214__27	0.0492180477917289	UP	1.9672313258745	0.0741625595835273	Glioma: MTOR
hsa05214__48	0.0492180477917289	UP	1.9672313258745	0.0741625595835273	Glioma: MTOR*
hsa05162__44	0.0504616638747904	UP	1.95656304319623	0.0759755339909705	Measles: PRKCQ
hsa04390__76	0.0509664302507696	DOWN	-1.95229573012491	0.0766740772147287	Hippo signaling pathway: MYC
hsa05213__31	0.0510932804626663	DOWN	-1.95122890185709	0.0768034191914799	Endometrial cancer: MYC
hsa04917__40	0.0517315034971388	UP	1.94589476051795	0.0777006355484603	Prolactin signaling pathway: TH
hsa04151__35	0.051859945341137	DOWN	-1.94482793225012	0.0777692236999173	PI3K-Akt signaling pathway: CCND1
hsa04261__72	0.051859945341137	DOWN	-1.94482793225012	0.0777692236999173	Adrenergic signaling in cardiomyocytes: ATP2B1
hsa04022__9	0.0526362112351689	DOWN	-1.93842696264315	0.0788075226381533	cGMP-PKG signaling pathway: ITPR1
hsa04115__34	0.0526362112351689	DOWN	-1.93842696264315	0.0788075226381533	p53 signaling pathway: ZMAT3
hsa04022__57	0.0527665284930344	UP	1.93736013437532	0.0789397349031939	cGMP-PKG signaling pathway: C00144
hsa04210__71	0.053686319536657	DOWN	-1.92989233650053	0.0802518650830378	Apoptosis: GADD45G
hsa04723__42	0.0538188046312537	DOWN	-1.9288255082327	0.0802583602397823	Retrograde endocannabinoid signaling: KCNJ3
hsa04723__50	0.0538188046312537	DOWN	-1.9288255082327	0.0802583602397823	Retrograde endocannabinoid signaling: KCNJ3*
hsa04921__41	0.0538188046312537	UP	1.9288255082327	0.0802583602397823	Oxytocin signaling pathway: PTGS2
hsa04370__28	0.0550234968167074	UP	1.91922405382225	0.0817952140178743	VEGF signaling pathway: SHC2
hsa04540__14 16	0.0550234968167074	UP	1.91922405382225	0.0817952140178743	Gap junction: GJA1 GJA1
hsa04540__14 15	0.0550234968167074	UP	1.91922405382225	0.0817952140178743	Gap junction: GJA1 GJA1*
hsa04612__18	0.0550234968167074	UP	1.91922405382225	0.0817952140178743	Antigen processing and presentation: KIR2DS2
hsa04068__50	0.0551587286370085	DOWN	-1.91815722555442	0.0819314238015328	FoxO signaling pathway: TNFSF10
hsa04919__29	0.0555660873708962	DOWN	-1.91495674075094	0.0824062179715185	Thyroid hormone signaling pathway: HIF1A
hsa05200__203	0.0555660873708962	UP	1.91495674075094	0.0824062179715185	Pathways in cancer: TGFA*
hsa04270__48	0.0558390500495209	UP	1.91282308421528	0.0827457216427838	Vascular smooth muscle contraction: KCNMB2*
hsa05205__431	0.0570812405288275	UP	1.90322162980483	0.0845198195064358	Proteoglycans in cancer: CDKN1A*
hsa04710__5	0.0572206698224122	DOWN	-1.90215480153701	0.0846595579498524	Circadian rhythm: RORA
hsa04925__5	0.0573603822637734	UP	1.90108797326918	0.084799495101204	Aldosterone synthesis and secretion: KCNK3
hsa04014__63	0.0577812226322346	DOWN	-1.8978874884657	0.0853544947531201	Ras signaling pathway: TIAM1*
hsa04740__21	0.0586306045367604	DOWN	-1.89148651885873	0.0865411672620368	Olfactory transduction: PDE1A
hsa04621__33 35	0.0587731713501689	UP	1.8904196905909	0.0866835078233654	NOD-like receptor signaling pathway: NLRC4 PYCARD
hsa04024__109	0.0597792189177785	UP	1.88295189271611	0.0880981587031419	cAMP signaling pathway: BDNF
hsa05152__81	0.0603604885405745	UP	1.87868457964479	0.0888850767772253	Tuberculosis: IFNA1
hsa05200__129 130	0.0619831786750888	DOWN	-1.86694946869869	0.0911317626999153	Pathways in cancer: CTBP1 HDAC1
hsa05220__12 13	0.0619831786750888	DOWN	-1.86694946869869	0.0911317626999153	Chronic myeloid leukemia: HDAC1 CTBP1
hsa04210__57	0.0622820573495347	UP	1.86481581216303	0.091499597935712	Apoptosis: BAK1
hsa04014__24	0.0625821272523124	DOWN	-1.86268215562738	0.091868607114918	Ras signaling pathway: PLD1
hsa04010__129	0.062732609969327	UP	1.86161532735955	0.0920176222735093	MAPK signaling pathway: FOS
hsa05161__30	0.0628833917597452	DOWN	-1.86054849909172	0.09216684330465	Hepatitis B: MYC
hsa04022__45	0.0630344730460044	UP	1.85948167082389	0.0923162703456293	cGMP-PKG signaling pathway: CREB3
hsa05145__67	0.0631858542506989	UP	1.85841484255607	0.0924659035335383	Toxoplasmosis: BAD
hsa05169__117	0.064561851226653	DOWN	-1.84881338814562	0.0944060065796739	Epstein-Barr virus infection: CDKN1A
hsa04932__97	0.0647162548920308	UP	1.84774655987779	0.0945581982442658	Non-alcoholic fatty liver disease (NAFLD): TNF*
hsa05164__90	0.0667513736632361	DOWN	-1.83387779239603	0.0974559682309407	Influenza A: MAPK1
hsa05200__215	0.0669100800758485	DOWN	-1.8328109641282	0.0976118326572355	Pathways in cancer: CSF1R
hsa05145__8	0.0670690970193032	UP	1.83174413586037	0.0977679079125451	Toxoplasmosis: NFKB1
hsa04115__36	0.0675480152979587	DOWN	-1.82854365105689	0.0983897060037709	p53 signaling pathway: EI24
hsa05223__9	0.0690016770283344	UP	1.81894219664644	0.100429241778653	Non-small cell lung cancer: BAD
hsa04913__21	0.0691647697068214	DOWN	-1.81787536837861	0.100510906635048	Ovarian steroidogenesis: CYP17A1
hsa04913__22	0.0691647697068214	DOWN	-1.81787536837861	0.100510906635048	Ovarian steroidogenesis: CYP17A1*
hsa04933__43	0.069655948510611	UP	1.81467488357512	0.10114646619122	AGE-RAGE signaling pathway in diabetic complications: CASP3
hsa05205__451	0.0709797729834797	UP	1.8061402574325	0.102989184120431	Proteoglycans in cancer: KDR**
hsa04115__15	0.0713139327470746	DOWN	-1.80400660089685	0.103394197246723	p53 signaling pathway: TSC2
hsa04151__99	0.072493659985523	DOWN	-1.79653880302205	0.105023582970546	PI3K-Akt signaling pathway: MYB
hsa05200__199	0.0726634893571125	DOWN	-1.79547197475422	0.10510754157199	Pathways in cancer: BCL2L1**
hsa05220__3	0.0726634893571125	DOWN	-1.79547197475422	0.10510754157199	Chronic myeloid leukemia: BCL2L1
hsa05216__14	0.0736893164782021	DOWN	-1.78907100514726	0.106509404355801	Thyroid cancer: MAPK1*
hsa04066__47	0.0743797574287507	UP	1.78480369207595	0.107424722681493	HIF-1 signaling pathway: PGK1
hsa04910__39	0.0747269550944912	UP	1.78267003554029	0.107760513140866	Insulin signaling pathway: BAD
hsa05120__50	0.0747269550944912	UP	1.78267003554029	0.107760513140866	Epithelial cell signaling in Helicobacter pylori infection: EGFR
hsa05142__49	0.0757764982018904	UP	1.77626906593332	0.109190214816988	Chagas disease (American trypanosomiasis): ADCY1
hsa04930__10	0.0761290074327565	DOWN	-1.77413540939767	0.109614103422337	Type II diabetes mellitus: C00031
hsa04024__24	0.0763057630247339	DOWN	-1.77306858112984	0.109784478348756	cAMP signaling pathway: PLN
hsa04728__61	0.0768380388821385	UP	1.76986809632636	0.110465703947619	Dopaminergic synapse: KCNJ3
hsa04724__67	0.0771945680021064	UP	1.7677344397907	0.110893419935748	Glutamatergic synapse: PLD1
hsa04151__33	0.0780917908930767	DOWN	-1.76240029845156	0.11209661962421	PI3K-Akt signaling pathway: TP53
hsa04068__42	0.0788156663614372	DOWN	-1.75813298538025	0.112879296991537	FoxO signaling pathway: CDKN2D
hsa04024__31	0.0789974856540028	UP	1.75706615711242	0.112879296991537	cAMP signaling pathway: C00165
hsa04024__32	0.0789974856540028	UP	1.75706615711242	0.112879296991537	cAMP signaling pathway: C01245
hsa04915__3 11	0.0789974856540028	UP	1.75706615711242	0.112879296991537	Estrogen signaling pathway: ESR1 C00951
hsa04915__12 14	0.0789974856540028	UP	1.75706615711242	0.112879296991537	Estrogen signaling pathway: ESR1 FOS
hsa04915__12 13	0.0789974856540028	UP	1.75706615711242	0.112879296991537	Estrogen signaling pathway: ESR1 C00951*
hsa04620__76	0.0791796459805588	DOWN	-1.75599932884459	0.113053613067986	Toll-like receptor signaling pathway: CCL3L3
hsa05218__9	0.0799117062663466	DOWN	-1.75173201577328	0.114012221772563	Melanoma: CCND1
hsa04922__24	0.0810194283080916	UP	1.74533104616632	0.115504936108425	Glucagon signaling pathway: PFKL
hsa04064__135	0.0813923278126974	DOWN	-1.74319738963066	0.115948585261606	NF-kappa B signaling pathway: CCL19
hsa04919__46	0.0817659410702556	DOWN	-1.74106373309501	0.116392578235614	Thyroid hormone signaling pathway: ATP1B4
hsa04152__77	0.0825173412365457	UP	1.73679642002369	0.11728448122804	AMPK signaling pathway: CCND1
hsa04510__44	0.0825173412365457	DOWN	-1.73679642002369	0.11728448122804	Focal adhesion: BCL2
hsa04066__56	0.0832743293272021	DOWN	-1.73252910695238	0.118181619943967	HIF-1 signaling pathway: TEK
hsa04971__39	0.0832743293272021	UP	1.73252910695238	0.118181619943967	Gastric acid secretion: EZR
hsa05215__14	0.0836549274905665	DOWN	-1.73039545041673	0.118632157550773	Prostate cancer: CCND1
hsa04213__2	0.0848051799557129	DOWN	-1.72399448080976	0.120172649424423	Longevity regulating pathway - multiple species: RPS6KB1
hsa04151__73	0.0875388843566646	UP	1.70905888506017	0.123952949288751	PI3K-Akt signaling pathway: MAPK1
hsa04750__59	0.089132647609792	DOWN	-1.70052425891755	0.126114642212951	Inflammatory mediator regulation of TRP channels: TRPV2
hsa04668__116	0.0895347191640781	DOWN	-1.69839060238189	0.126397999481069	TNF signaling pathway: PGAM5
hsa04740__33	0.0895347191640781	DOWN	-1.69839060238189	0.126397999481069	Olfactory transduction: CNGA3*
hsa05161__57	0.0895347191640781	UP	1.69839060238189	0.126397999481069	Hepatitis B: STAT3*
hsa04550__62 63	0.0907497028526646	UP	1.69198963277493	0.128017035780898	Signaling pathways regulating pluripotency of stem cells: SMAD2 SMAD4
hsa05220__6	0.0909534834801671	DOWN	-1.6909228045071	0.12820824865659	Chronic myeloid leukemia: TP53
hsa04115__17	0.0913621486274323	UP	1.68878914797144	0.128687764071173	p53 signaling pathway: TP73
hsa05161__130	0.0921839065608577	UP	1.68452183490013	0.129747985339215	Hepatitis B: FASLG*
hsa05160__37	0.0929125851499116	DOWN	-1.68025452182882	0.130675709204105	Hepatitis C: STAT3
hsa05200__52	0.0951069113307869	DOWN	-1.66958623915054	0.133661844719932	Pathways in cancer: CDKN1B
hsa04068__57	0.0955304787992604	UP	1.66745258261489	0.134156778523027	FoxO signaling pathway: IL7R
hsa04668__138	0.0968102498769072	UP	1.66105161300792	0.135751089193066	TNF signaling pathway: NFKB1*
hsa04916__9	0.0968102498769072	DOWN	-1.66105161300792	0.135751089193066	Melanogenesis: PRKACA
hsa05200__213	0.0985378996839716	DOWN	-1.6525169868653	0.138070629012813	Pathways in cancer: CSF2RA
hsa05140__43	0.0991920808941995	UP	1.64931650206181	0.138883695976305	Leishmaniasis: MAPK14
hsa04110__43 83 84 85	0.100510838375491	UP	1.64291553245485	0.140520733115735	Cell cycle: SMC1B SMC3 STAG1 RAD21
hsa05016__55	0.100510838375491	UP	1.64291553245485	0.140520733115735	Huntington's disease: TGM2
hsa04932__7	0.100731983782135	UP	1.64184870418702	0.140725202622031	Non-alcoholic fatty liver disease (NAFLD): SREBF1
hsa05321__74	0.101397747099285	UP	1.63864821938353	0.1415500496282	Inflammatory bowel disease (IBD): IL5
hsa04152__56	0.102739784041296	UP	1.63224724977657	0.143210722710383	AMPK signaling pathway: FASN
hsa04917__31	0.102739784041296	DOWN	-1.63224724977657	0.143210722710383	Prolactin signaling pathway: GALT
hsa04919__38	0.102964824281618	DOWN	-1.63118042150874	0.143418016920059	Thyroid hormone signaling pathway: TP53
hsa04340__15	0.103868907746709	DOWN	-1.62691310843743	0.14435627045567	Hedgehog signaling pathway: HHIP
hsa04350__44 45	0.103868907746709	UP	1.62691310843743	0.14435627045567	TGF-beta signaling pathway: TGFBR2 TGFBR1
hsa04550__66	0.103868907746709	DOWN	-1.62691310843743	0.14435627045567	Signaling pathways regulating pluripotency of stem cells: MYC
hsa04550__69	0.104323308930599	UP	1.62477945190177	0.144880633762451	Signaling pathways regulating pluripotency of stem cells: ID1
hsa04920__37	0.105007869572707	UP	1.62157896709829	0.145723624022981	Adipocytokine signaling pathway: IRS1
hsa04115__25	0.106156722550633	DOWN	-1.61624482575915	0.147209211566524	p53 signaling pathway: CD82
hsa05217__4	0.107781834606328	UP	1.60877702788436	0.149352556950804	Basal cell carcinoma: PTCH1
hsa04664__47	0.110137520192861	DOWN	-1.59810874520608	0.15250434815209	Fc epsilon RI signaling pathway: MAPK8
hsa04931__144	0.112292246409068	UP	1.58850729079563	0.155373439619027	Insulin resistance: C00533*
hsa05215__24	0.113260510475274	UP	1.58423997772432	0.15659786547685	Prostate cancer: CDKN1A
hsa04022__65	0.114725225867599	DOWN	-1.57783900811735	0.158506396621484	cGMP-PKG signaling pathway: PDE2A
hsa05016__12	0.114970787693942	DOWN	-1.57677217984952	0.158728956706037	Huntington's disease: REST
hsa04390__89	0.115957171931659	DOWN	-1.57250486677821	0.159973220308067	Hippo signaling pathway: ID2
hsa04540__11	0.116204804297947	UP	1.57143803851038	0.160197232043905	Gap junction: C00780
hsa04750__90	0.116452852015621	UP	1.57037121024255	0.160421487490727	Inflammatory mediator regulation of TRP channels: C01245**
hsa05145__10	0.117949883860367	UP	1.56397024063559	0.162364711922073	Toxoplasmosis: MAPK8
hsa04917__45	0.118704040493241	DOWN	-1.5607697558321	0.163283229931772	Prolactin signaling pathway: SLC2A2
hsa04662__29	0.119208908288425	DOWN	-1.55863609929645	0.163857745920959	B cell receptor signaling pathway: RAC1
hsa04931__77	0.119714715884077	DOWN	-1.55650244276079	0.164432712826155	Insulin resistance: PPP2R4**
hsa04666__20	0.120223690772793	DOWN	-1.55436878622514	0.164890740848233	Fc gamma R-mediated phagocytosis: PLA2G4B
hsa05200__217	0.120223690772793	UP	1.55436878622514	0.164890740848233	Pathways in cancer: E2F1*
hsa05164__19	0.122015820632505	UP	1.54690098835034	0.167226642573652	Influenza A: NFKB1
hsa04725__64	0.122273535131138	UP	1.54583416008251	0.16733574108624	Cholinergic synapse: KCNJ3
hsa04726__38	0.122273535131138	DOWN	-1.54583416008251	0.16733574108624	Serotonergic synapse: PLA2G4B
hsa04014__67	0.122531674840653	UP	1.54476733181469	0.167445103291336	Ras signaling pathway: RAPGEF5*
hsa04152__82	0.122531674840653	DOWN	-1.54476733181469	0.167445103291336	AMPK signaling pathway: HMGCR
hsa04520__69	0.123568493928843	DOWN	-1.54050001874337	0.168616703044515	Adherens junction: IQGAP1**
hsa05145__35	0.123568493928843	UP	1.54050001874337	0.168616703044515	Toxoplasmosis: CASP3
hsa04915__66	0.123828765796119	UP	1.53943319047555	0.168849238701675	Estrogen signaling pathway: AKT3*
hsa04330__11	0.125662665754769	UP	1.53196539260075	0.171101557212472	Notch signaling pathway: PTCRA
hsa04666__30 44	0.125662665754769	UP	1.53196539260075	0.171101557212472	Fc gamma R-mediated phagocytosis: C04637 GSN
hsa04390__60	0.12672007029256	DOWN	-1.52769807952944	0.172416373700014	Hippo signaling pathway: CTGF*
hsa04722__33	0.126985500653303	UP	1.52663125126161	0.172652500526452	Neurotrophin signaling pathway: BAD
hsa04917__68	0.12778438831137	DOWN	-1.52343076645813	0.173613062644298	Prolactin signaling pathway: CCND1
hsa04115__49	0.128587179257011	DOWN	-1.52023028165465	0.174577535999945	p53 signaling pathway: MDM2*
hsa04919__88	0.132660060596044	DOWN	-1.50422785763723	0.179977078599254	Thyroid hormone signaling pathway: FOXO1
hsa04213__54	0.133486497247397	UP	1.50102737283375	0.180837150921312	Longevity regulating pathway - multiple species: SOD2*
hsa05152__77	0.133486497247397	DOWN	-1.50102737283375	0.180837150921312	Tuberculosis: IL12A
hsa04360__40 139	0.133762859683552	UP	1.49996054456592	0.18095062155896	Axon guidance: UNC5D DCC
hsa05169__29	0.133762859683552	DOWN	-1.49996054456592	0.18095062155896	Epstein-Barr virus infection: FCER2
hsa04670__39	0.134039664551424	UP	1.49889371629809	0.181194625677788	Leukocyte transendothelial migration: MAPK14
hsa04520__64	0.13487273767095	UP	1.49569323149461	0.182189700994763	Adherens junction: CTNND1**
hsa04062__35 36 37	0.138529032455347	UP	1.48182446401284	0.186994290218101	Chemokine signaling pathway: PARD3 PRKCZ TIAM1
hsa05321__19	0.138813418436993	UP	1.48075763574502	0.187243656312354	Inflammatory bowel disease (IBD): TNF
hsa04912__43	0.13938353911022	UP	1.47862397920936	0.187877812043116	GnRH signaling pathway: PTK2B
hsa05220__15	0.139955460631974	DOWN	-1.47649032267371	0.188513484249089	Chronic myeloid leukemia: MYC
hsa04611__34	0.140242097672712	DOWN	-1.47542349440588	0.188764256108184	Platelet activation: C02198*
hsa05152__126	0.142842188408048	UP	1.46582203999543	0.192126322132228	Tuberculosis: NOS2
hsa04971__49	0.144302583506264	UP	1.46048789865629	0.193951755656845	Gastric acid secretion: KCNJ1
hsa04014__97	0.145184297875287	UP	1.4572874138528	0.194997352185607	Ras signaling pathway: PAK4
hsa04912__14	0.147555708030273	UP	1.44875278771018	0.198040839563488	GnRH signaling pathway: ATF4
hsa04211__57	0.14845258010452	DOWN	-1.4455523029067	0.199102354044535	Longevity regulating pathway - mammal: ATG5
hsa04913__19	0.148752460839454	DOWN	-1.44448547463887	0.199362249584404	Ovarian steroidogenesis: STAR
hsa04151__98	0.150561466639119	UP	1.4380845050319	0.201642905071208	PI3K-Akt signaling pathway: BCL2L1*
hsa04066__48	0.15147223560428	UP	1.43488402022842	0.202429822688792	HIF-1 signaling pathway: PFKFB3
hsa05110__12	0.15147223560428	UP	1.43488402022842	0.202429822688792	Vibrio cholerae infection: C00080
hsa05120__35	0.15147223560428	UP	1.43488402022842	0.202429822688792	Epithelial cell signaling in Helicobacter pylori infection: C00080
hsa05205__270	0.151776756015607	DOWN	-1.43381719196059	0.202692625837474	Proteoglycans in cancer: MAPK1****
hsa05169__30	0.152693114641437	UP	1.43061670715711	0.203771564212543	Epstein-Barr virus infection: FGR
hsa04390__74	0.153306355199857	UP	1.42848305062145	0.204444741959214	Hippo signaling pathway: AXIN1
hsa04728__24	0.153613668336974	DOWN	-1.42741622235363	0.204709278585229	Dopaminergic synapse: SLC6A3
hsa04010__88 92	0.154229725522432	UP	1.42528256581797	0.205093881285668	MAPK signaling pathway: ECSIT TRAF6
hsa05031__96	0.154229725522432	DOWN	-1.42528256581797	0.205093881285668	Amphetamine addiction: PDYN
hsa05134__69	0.154229725522432	UP	1.42528256581797	0.205093881285668	Legionellosis: IL1B*
hsa04727__47	0.157651595753259	DOWN	-1.41354745487186	0.209496003126148	GABAergic synapse: CACNA1A*
hsa05134__73	0.158279887008207	DOWN	-1.41141379833621	0.210182266917612	Legionellosis: CXCL1
hsa05161__32	0.159542154998113	DOWN	-1.4071464852649	0.211708834210066	Hepatitis B: STAT3
hsa04950__7	0.1604938419199	UP	1.40394600046141	0.212821403646783	Maturity onset diabetes of the young: FOXA3
hsa05217__22	0.163052644375503	DOWN	-1.39541137431879	0.216062001961615	Basal cell carcinoma: LEF1
hsa05166__99	0.163697126161134	DOWN	-1.39327771778314	0.2167631430985	HTLV-I infection: JUN
hsa05164__35	0.164343525961004	DOWN	-1.39114406124748	0.217465834704736	Influenza A: IL18
hsa04730__20	0.164991846531751	UP	1.38901040471182	0.218170077152119	Long-term depression: C00025
hsa05142__29	0.166948360295429	DOWN	-1.38260943510486	0.220601947253946	Chagas disease (American trypanosomiasis): NOS2
hsa04810__21 82	0.16760439132865	DOWN	-1.3804757785692	0.220847581561384	Regulation of actin cytoskeleton: CFL1 ACTB
hsa04930__13	0.16760439132865	UP	1.3804757785692	0.220847581561384	Type II diabetes mellitus: C00162
hsa05205__337	0.16760439132865	DOWN	-1.3804757785692	0.220847581561384	Proteoglycans in cancer: CTNNB1**
hsa05231__50	0.16760439132865	UP	1.3804757785692	0.220847581561384	Choline metabolism in cancer: WASF2
hsa04261__3	0.167933132081148	UP	1.37940895030137	0.221125686881904	Adrenergic signaling in cardiomyocytes: RYR2
hsa04012__29	0.168262356774797	UP	1.37834212203355	0.22124910313495	ErbB signaling pathway: STAT5A*
hsa05215__8	0.168262356774797	UP	1.37834212203355	0.22124910313495	Prostate cancer: NFKBIA
hsa04915__30	0.16859206574676	DOWN	-1.37727529376572	0.221527616460253	Estrogen signaling pathway: CREB3*
hsa04062__33	0.169252937871241	UP	1.37514163723006	0.22208538425982	Chemokine signaling pathway: WAS
hsa05200__80	0.169252937871241	DOWN	-1.37514163723006	0.22208538425982	Pathways in cancer: TP53
hsa04151__4	0.169584101695042	DOWN	-1.37407480896223	0.22236463857989	PI3K-Akt signaling pathway: RPS6
hsa05145__4 5	0.171247211800018	UP	1.3687406676231	0.224388780315365	Toxoplasmosis: MAP3K7 TAB1
hsa04210__70	0.172250922623831	DOWN	-1.36554018281961	0.225546678473991	Apoptosis: CFLAR*
hsa05212__31	0.173933543896737	UP	1.36020604148047	0.227591315447053	Pancreatic cancer: RAC1*
hsa04915__58	0.175288457417728	UP	1.35593872840916	0.229204600896249	Estrogen signaling pathway: CREB3***
hsa04022__58	0.177335570588344	DOWN	-1.34953775880219	0.231398289677429	cGMP-PKG signaling pathway: MYH7
hsa04151__27	0.177335570588344	UP	1.34953775880219	0.231398289677429	PI3K-Akt signaling pathway: FASLG
hsa04360__82	0.177335570588344	DOWN	-1.34953775880219	0.231398289677429	Axon guidance: ILK
hsa05132__55	0.177678480255235	UP	1.34847093053437	0.23168484691158	Salmonella infection: IL18
hsa04530__5 15	0.178021883387022	DOWN	-1.34740410226654	0.23197164971166	Tight junction: IGSF5 MPDZ
hsa05216__11	0.178365780302427	DOWN	-1.34633727399871	0.232258697982162	Thyroid cancer: MYC
hsa04931__47	0.179400436927594	UP	1.34313678919523	0.233444197359383	Insulin resistance: AKT2*
hsa04520__1 13	0.179746312151362	DOWN	-1.3420699609274	0.233732401752532	Adherens junction: SMAD4 SMAD2
hsa04664__46	0.181483125061976	DOWN	-1.33673581958826	0.235827656978875	Fc epsilon RI signaling pathway: PLA2G4B
hsa05145__33	0.18218132657476	DOWN	-1.33460216305261	0.236244798229106	Toxoplasmosis: STAT3
hsa05169__125	0.18218132657476	DOWN	-1.33460216305261	0.236244798229106	Epstein-Barr virus infection: STAT3
hsa05221__5	0.18218132657476	DOWN	-1.33460216305261	0.236244798229106	Acute myeloid leukemia: SPI1
hsa04971__37	0.182531173509474	UP	1.33353533478478	0.236535224154691	Gastric acid secretion: KCNQ1
hsa05205__195	0.182881518309834	UP	1.33246850651695	0.236825894489441	Proteoglycans in cancer: CDKN1A
hsa04933__56	0.184994059557435	UP	1.32606753690998	0.23923182237331	AGE-RAGE signaling pathway in diabetic complications: NFATC1
hsa05215__25	0.184994059557435	DOWN	-1.32606753690998	0.23923182237331	Prostate cancer: FOXO1
hsa05161__194	0.186768258180284	UP	1.32073339557084	0.241194197333852	Hepatitis B: TNF*
hsa05217__19	0.186768258180284	UP	1.32073339557084	0.241194197333852	Basal cell carcinoma: HHIP
hsa05200__226	0.187481446222983	UP	1.31859973903519	0.241948926822106	Pathways in cancer: CDKN1A*
hsa04350__27	0.189633071034309	DOWN	-1.31219876942822	0.244557680489683	TGF-beta signaling pathway: ACVR2A*
hsa04742__46	0.190715607450906	DOWN	-1.30899828462474	0.245785066118144	Taste transduction: P2RY1
hsa04911__24	0.192166232493544	UP	1.30473097155343	0.247146030701827	Insulin secretion: INS
hsa04917__57	0.192166232493544	DOWN	-1.30473097155343	0.247146030701827	Prolactin signaling pathway: ESR1
hsa05150__1 2 3	0.192166232493544	UP	1.30473097155343	0.247146030701827	Staphylococcus aureus infection: CFD C3 CFB
hsa04211__62	0.193259456748129	UP	1.30153048674994	0.248382024096945	Longevity regulating pathway - mammal: EHMT2
hsa04340__49	0.19582806578879	DOWN	-1.29406268887515	0.251511234188063	Hedgehog signaling pathway: CCND1
hsa04620__34	0.196936524963443	UP	1.29086220407166	0.252762110933271	Toll-like receptor signaling pathway: IL1B
hsa04024__111	0.198794154066907	UP	1.28552806273253	0.2549721607452	cAMP signaling pathway: JUN
hsa05142__18	0.201416307087184	DOWN	-1.27806026485773	0.258159100284324	Chagas disease (American trypanosomiasis): FOS
hsa05164__31 32 33	0.202169992181764	UP	1.27592660832208	0.258948476693616	Influenza A: NLRP3 PYCARD CASP1
hsa04727__17 37	0.203304647840015	DOWN	-1.27272612351859	0.260224409599038	GABAergic synapse: GABRA1 GPHN
hsa04622__11	0.203683869321862	UP	1.27165929525076	0.260355095548149	RIG-I-like receptor signaling pathway: IRF7
hsa05166__32	0.203683869321862	UP	1.27165929525076	0.260355095548149	HTLV-I infection: STAT5A
hsa05221__27	0.206736112290865	DOWN	-1.26312466910814	0.264076923857604	Acute myeloid leukemia: PIM2
hsa05217__10	0.207119965022778	DOWN	-1.26205784084031	0.264387509699593	Basal cell carcinoma: PTCH1*
hsa04650__39	0.207889221589427	UP	1.25992418430466	0.265189305747817	Natural killer cell mediated cytotoxicity: FAS
hsa05162__93	0.211376520035657	UP	1.25032272989421	0.269454871877205	Measles: TP53
hsa04550__17	0.211766593000046	DOWN	-1.24925590162638	0.26976910389633	Signaling pathways regulating pluripotency of stem cells: AKT3
hsa04919__84	0.213332087240648	DOWN	-1.24498858855507	0.271395390606078	Thyroid hormone signaling pathway: TP53*
hsa05130__55	0.213332087240648	DOWN	-1.24498858855507	0.271395390606078	Pathogenic Escherichia coli infection: ACTB
hsa04062__25	0.218877061785798	UP	1.23005299280548	0.278073021700821	Chemokine signaling pathway: ROCK1
hsa04660__44	0.218877061785798	DOWN	-1.23005299280548	0.278073021700821	T cell receptor signaling pathway: PAK4
hsa04015__95	0.219677575075644	UP	1.22791933626982	0.278901461869686	Rap1 signaling pathway: THBS1
hsa05016__60	0.220480187512347	DOWN	-1.22578567973417	0.279542693883738	Huntington's disease: CASP3*
hsa05134__35	0.220480187512347	DOWN	-1.22578567973417	0.279542693883738	Legionellosis: CASP3
hsa04722__70	0.223711665332993	UP	1.21725105359154	0.283448563156233	Neurotrophin signaling pathway: ZNF274
hsa04530__7 52	0.224524800831839	DOWN	-1.21511739705589	0.284287129894222	Tight junction: PARD6A MPP5
hsa04062__38	0.225340046307467	UP	1.21298374052023	0.285127237044936	Chemokine signaling pathway: NCF1
hsa04210__64	0.226157403513962	UP	1.21085008398458	0.285776571084556	Apoptosis: TNFRSF10D*
hsa05212__54	0.226157403513962	DOWN	-1.21085008398458	0.285776571084556	Pancreatic cancer: C00416
hsa04360__20	0.226976874190703	DOWN	-1.20871642744892	0.286619318954524	Axon guidance: ROCK1
hsa03320__46	0.229034808596108	DOWN	-1.20338228610978	0.289023777939615	PPAR signaling pathway: APOA2
hsa05152__82	0.230275925869441	DOWN	-1.2001818013063	0.290394942757503	Tuberculosis: IL6
hsa04151__96	0.230690692322692	DOWN	-1.19911497303847	0.290722877849992	PI3K-Akt signaling pathway: BCL2
hsa05162__78	0.231105989468969	UP	1.19804814477064	0.29105104169718	Measles: FAS
hsa05130__28	0.231938176662679	UP	1.19591448823499	0.291903438679956	Pathogenic Escherichia coli infection: ROCK1
hsa04630__36	0.234867578608414	UP	1.18844669036019	0.295392356228386	Jak-STAT signaling pathway: GFAP
hsa05130__26	0.236553237758147	UP	1.18417937728888	0.297313400500039	Pathogenic Escherichia coli infection: CTNNB1
hsa04066__58	0.23782308304711	DOWN	-1.1809788924854	0.298709607650749	HIF-1 signaling pathway: EDN1
hsa05132__20	0.238247432677768	UP	1.17991206421757	0.29904270273983	Salmonella infection: ACTB
hsa04933__26	0.238672316558764	DOWN	-1.17884523594974	0.299176306079998	AGE-RAGE signaling pathway in diabetic complications: IL6
hsa05213__29	0.238672316558764	DOWN	-1.17884523594974	0.299176306079998	Endometrial cancer: CCND1
hsa05231__38	0.242090643024829	DOWN	-1.17031060980712	0.303258878829102	Choline metabolism in cancer: RPS6KB1
hsa04612__17 28	0.24424450818693	UP	1.16497646846798	0.305753118509822	Antigen processing and presentation: CD4 HLA-DMA
hsa04622__6	0.248592519817075	UP	1.1543081857897	0.310988911275821	RIG-I-like receptor signaling pathway: NFKB1
hsa05152__90	0.249468578763078	DOWN	-1.15217452925405	0.311877218560095	Tuberculosis: CR1
hsa04728__32	0.250346793013009	UP	1.15004087271839	0.312767037281545	Dopaminergic synapse: CREB3
hsa05120__19	0.254325463349284	UP	1.14043941830794	0.317526608394222	Epithelial cell signaling in Helicobacter pylori infection: CXCL1
hsa04933__19	0.255215554469444	DOWN	-1.13830576177229	0.318426312648131	AGE-RAGE signaling pathway in diabetic complications: TGFBR2
hsa04610__7	0.25789881309712	UP	1.13190479216532	0.321560630265089	Complement and coagulation cascades: C00290
hsa04725__53	0.258797374112135	DOWN	-1.12977113562966	0.3222535616709	Cholinergic synapse: CHRNA7
hsa04728__44	0.258797564960824	DOWN	-1.12977113562966	0.3222535616709	Dopaminergic synapse: FOS
hsa04114__56	0.260601574009888	UP	1.12550382255835	0.324285005009656	Oocyte meiosis: REC8
hsa04024__62	0.264235644120311	DOWN	-1.11696919641573	0.328589527003351	cAMP signaling pathway: BAD
hsa04722__37	0.26514959535121	UP	1.11483553988007	0.329290211278865	Neurotrophin signaling pathway: NFKB1
hsa04917__47	0.26514959535121	DOWN	-1.11483553988007	0.329290211278865	Prolactin signaling pathway: INS
hsa04921__60	0.267443993586242	DOWN	-1.10950139854093	0.331920253598778	Oxytocin signaling pathway: ELK1
hsa04024__59	0.267904506247379	UP	1.10843457027311	0.332272321609786	cAMP signaling pathway: MLLT4
hsa04610__45	0.269752004275701	DOWN	-1.1041672572018	0.334343018492113	Complement and coagulation cascades: C4A
hsa04919__39	0.27114335081261	DOWN	-1.10096677239831	0.335845982977518	Thyroid hormone signaling pathway: ESR1
hsa04210__10	0.274408921138768	UP	1.09349897452352	0.339666905678356	Apoptosis: BIRC2
hsa05150__14	0.276286823024976	UP	1.08923166145221	0.341541596026391	Staphylococcus aureus infection: FPR1
hsa05164__77	0.276286974965468	DOWN	-1.08923166145221	0.341541596026391	Influenza A: CASP9
hsa04722__50	0.276757854640205	UP	1.08816483318438	0.341898756652824	Neurotrophin signaling pathway: RHOA
hsa05218__14	0.278173774170887	UP	1.08496434838089	0.343422156154465	Melanoma: BAD
hsa04115__23	0.280544580792853	DOWN	-1.07963020704176	0.346121646296632	p53 signaling pathway: PTEN
hsa04210__69	0.283407614969522	DOWN	-1.07322923743479	0.349424480661242	Apoptosis: PTPN13
hsa05161__92	0.283886704661545	UP	1.07216240916696	0.349785651186258	Hepatitis B: NFKBIA
hsa05014__13	0.286290375156189	DOWN	-1.06682826782782	0.35228527499573	Amyotrophic lateral sclerosis (ALS): CASP3
hsa05161__10	0.286290375156189	DOWN	-1.06682826782782	0.35228527499573	Hepatitis B: CASP3
hsa04022__3	0.289192878338441	DOWN	-1.06042729822085	0.355623964920112	cGMP-PKG signaling pathway: MYL9
hsa04015__3	0.290651538449169	DOWN	-1.05722681341737	0.357183937701759	Rap1 signaling pathway: MAPK1
hsa04933__21	0.291138856496951	UP	1.05615998514954	0.357548961671746	AGE-RAGE signaling pathway in diabetic complications: SMAD4
hsa05100__55	0.293093620442422	DOWN	-1.05189267207823	0.35971450869452	Bacterial invasion of epithelial cells: ACTB*
hsa04919__99	0.296535609736279	DOWN	-1.04442487420344	0.363701312463752	Thyroid hormone signaling pathway: WNT4
hsa05168__138	0.298514553843545	DOWN	-1.04015756113213	0.365889658624933	Herpes simplex infection: CHUK
hsa04670__73	0.301499468782221	DOWN	-1.03375659152516	0.368826498594917	Leukocyte transendothelial migration: MYL12B*
hsa05200__223	0.301499468782221	UP	1.03375659152516	0.368826498594917	Pathways in cancer: CCND1****
hsa05221__17	0.301499468782221	UP	1.03375659152516	0.368826498594917	Acute myeloid leukemia: CCND1
hsa05160__70	0.301998880013267	DOWN	-1.03268976325733	0.369197069320057	Hepatitis C: CDKN1A
hsa05205__142	0.30249884146561	UP	1.0316229349895	0.369567830373135	Proteoglycans in cancer: CTNNB1
hsa04015__14	0.302999353175808	UP	1.03055610672168	0.369938781427773	Rap1 signaling pathway: MAPK14
hsa04750__53	0.304002027509927	DOWN	-1.02842245018602	0.370681252233065	Inflammatory mediator regulation of TRP channels: TRPM8
hsa05031__55	0.304002027509927	UP	1.02842245018602	0.370681252233065	Amphetamine addiction: GRIA1*
hsa04912__17	0.306013980746102	DOWN	-1.02415513711471	0.372892522582312	GnRH signaling pathway: MAPK14
hsa04666__50 52	0.30854130824454	UP	1.01882099577557	0.375485180175836	Fc gamma R-mediated phagocytosis: DNM2 AMPH
hsa04740__16	0.30854130824454	UP	1.01882099577557	0.375485180175836	Olfactory transduction: PRKG1
hsa04670__18	0.310064209720956	UP	1.01562051097209	0.377094271887169	Leukocyte transendothelial migration: CDH5
hsa04210__56	0.311082400719247	UP	1.01348685443643	0.378087859606381	Apoptosis: BAX
hsa05215__46	0.317753675353196	DOWN	-0.999618086954669	0.38594644860288	Prostate cancer: MTOR
hsa05200__195	0.318270705730077	UP	0.998551258686841	0.386324713221457	Pathways in cancer: BIRC8
hsa04150__31	0.322948763710711	DOWN	-0.988949804276391	0.391497243233823	mTOR signaling pathway: EIF4E
hsa05221__6	0.322948763710711	DOWN	-0.988949804276391	0.391497243233823	Acute myeloid leukemia: CEBPA
hsa04621__21 31 41	0.328198922060614	UP	0.978281521598113	0.397605270504122	NOD-like receptor signaling pathway: NLRP3 CARD8 CASP1
hsa04920__12	0.328726894672438	UP	0.977214693330285	0.397988295805098	Adipocytokine signaling pathway: C00165
hsa04261__4	0.329255560588765	DOWN	-0.976147865062457	0.398371666675009	Adrenergic signaling in cardiomyocytes: SLC8A1
hsa04261__66	0.331375442852125	DOWN	-0.971880551991146	0.400420872745429	Adrenergic signaling in cardiomyocytes: C01245
hsa05200__75	0.331375442852125	DOWN	-0.971880551991146	0.400420872745429	Pathways in cancer: MAPK8
hsa05152__97	0.333504130340264	DOWN	-0.967613238919834	0.402734100841488	Tuberculosis: IL18
hsa04727__8	0.335641620702993	DOWN	-0.963345925848523	0.405054980925448	GABAergic synapse: ADCY1
hsa04151__28	0.33832585858259	UP	0.958011784509384	0.408032277456153	PI3K-Akt signaling pathway: BCL2L11
hsa04972__23	0.339942998995349	UP	0.954811299705901	0.40971962483147	Pancreatic secretion: KCNMA1
hsa05152__68	0.344824093214553	DOWN	-0.94520984529545	0.414928833283259	Tuberculosis: CD74
hsa04014__100	0.345369183211824	UP	0.944143017027622	0.414928833283259	Ras signaling pathway: REL
hsa04723__40	0.345369183211824	UP	0.944143017027622	0.414928833283259	Retrograde endocannabinoid signaling: GRIA1
hsa04724__4	0.345369183211824	UP	0.944143017027622	0.414928833283259	Glutamatergic synapse: GRIA1
hsa05031__12	0.345369183211824	UP	0.944143017027622	0.414928833283259	Amphetamine addiction: GRIA1
hsa04920__31	0.345914822210748	UP	0.943076188759795	0.415318818488176	Adipocytokine signaling pathway: AGRP
hsa04620__22	0.347007746937483	UP	0.940942532224139	0.416364978605064	Toll-like receptor signaling pathway: CD86
hsa04913__36	0.34755503252396	DOWN	-0.939875703956311	0.416489736041149	Ovarian steroidogenesis: CYP19A1
hsa04913__37	0.34755503252396	DOWN	-0.939875703956311	0.416489736041149	Ovarian steroidogenesis: CYP19A1*
hsa04350__11	0.34865124977989	DOWN	-0.937742047420655	0.417537092629963	TGF-beta signaling pathway: SMAD4*
hsa05168__39 40	0.350850266506108	DOWN	-0.933474734349344	0.419902962270686	Herpes simplex infection: POU2F3 HCFC2
hsa04210__62	0.35195306471865	DOWN	-0.931341077813688	0.420954684026953	Apoptosis: TP53AIP1
hsa04012__56	0.353611372498365	UP	0.928140593010205	0.422669064201289	ErbB signaling pathway: JUN
hsa04918__10	0.354165237538822	UP	0.927073764742377	0.423061971605497	Thyroid hormone synthesis: TG
hsa04930__8	0.355830118761611	UP	0.923873279938894	0.424780681799916	Type II diabetes mellitus: C00022
hsa04024__2	0.356386174232148	UP	0.922806451671066	0.424904582095309	cAMP signaling pathway: CACNA1C
hsa04917__48	0.356386174232148	DOWN	-0.922806451671066	0.424904582095309	Prolactin signaling pathway: CCND2
hsa05012__57	0.360293883625522	DOWN	-0.915338653796271	0.429291190445374	Parkinson's disease: CASP3
hsa04010__64	0.360854315361517	UP	0.914271825528443	0.429686475642769	MAPK signaling pathway: DDIT3
hsa05010__59	0.361976818456281	DOWN	-0.912138168992788	0.43075012151954	Alzheimer's disease: LRP1
hsa04022__51	0.367055114498449	UP	0.902536714582337	0.436516810216826	cGMP-PKG signaling pathway: GTF2I
hsa04310__33	0.367622097855264	UP	0.90146988631451	0.436914561587629	Wnt signaling pathway: CCND1
hsa03320__61	0.370465190396655	UP	0.89613574497537	0.440015229301716	PPAR signaling pathway: APOA1
hsa05200__76	0.377920906275553	UP	0.882266977493609	0.44858710226896	Pathways in cancer: RAC1
hsa04115__21	0.379076089360996	DOWN	-0.880133320957953	0.449674224690222	p53 signaling pathway: DDB2
hsa04066__43	0.379654494743717	UP	0.879066492690125	0.449792431036219	HIF-1 signaling pathway: PFKL
hsa04660__30	0.379654494743717	UP	0.879066492690125	0.449792431036219	T cell receptor signaling pathway: CD40LG
hsa04925__34	0.380233442487438	DOWN	-0.877999664422297	0.449910981381547	Aldosterone synthesis and secretion: STAR
hsa05205__103	0.380233442487438	DOWN	-0.877999664422297	0.449910981381547	Proteoglycans in cancer: CCND1
hsa04920__10	0.383718509980197	UP	0.87159869481533	0.453748949183631	Adipocytokine signaling pathway: PCK1
hsa04012__3	0.384301249946698	DOWN	-0.870531866547503	0.454152231855249	ErbB signaling pathway: ELK1
hsa05210__23	0.38488453102788	UP	0.869465038279675	0.454555646638207	Colorectal cancer: CCND1
hsa05152__94	0.387223063238704	UP	0.865197725208364	0.45703023607131	Tuberculosis: CAMP
hsa04066__89	0.390158383732928	UP	0.859863583869224	0.460205651622204	HIF-1 signaling pathway: CDKN1A
hsa05205__188	0.390747066822699	UP	0.858796755601397	0.460610877390121	Proteoglycans in cancer: TNF
hsa04924__23	0.395475929713568	UP	0.850262129458774	0.465892960458806	Renin secretion: ITPR1
hsa04380__69	0.396069459614871	UP	0.849195301190946	0.466299821188184	Osteoclast differentiation: NFKB2
hsa04066__42	0.396663527127475	DOWN	-0.848128472923118	0.466706804929571	HIF-1 signaling pathway: HK1
hsa04022__66	0.397258132061608	DOWN	-0.847061644655291	0.467113911228887	cGMP-PKG signaling pathway: PDE3A
hsa04742__23 45	0.398448495783429	UP	0.844927988119635	0.46792848968247	Taste transduction: PKD1L3 PKD2L1
hsa05152__24 25	0.398448953428394	UP	0.844927988119635	0.46792848968247	Tuberculosis: ITGB2 ITGAM
hsa05200__198	0.399641922169126	DOWN	-0.842794331583979	0.469036334638219	Pathways in cancer: BCL2L1*
hsa04931__40	0.403834200484913	UP	0.835326533709185	0.473660713302841	Insulin resistance: PRKCZ
hsa04210__3	0.404435239166563	DOWN	-0.834259705441357	0.473774198499982	Apoptosis: BCL2L1
hsa04726__39	0.404435239166563	DOWN	-0.834259705441357	0.473774198499982	Serotonergic synapse: CACNA1C
hsa05152__51	0.406241563336312	UP	0.831059220637873	0.475593705613041	Tuberculosis: CASP3
hsa05210__22	0.407448450775632	UP	0.828925564102218	0.476709613329646	Colorectal cancer: MYC
hsa04370__38	0.409868629110367	UP	0.824658251030906	0.478944747573619	VEGF signaling pathway: BAD
hsa04971__55	0.409868629110367	UP	0.824658251030906	0.478944747573619	Gastric acid secretion: MYLK4
hsa04724__66	0.412905840395979	DOWN	-0.819324109691767	0.482193955316373	Glutamatergic synapse: PLA2G4B
hsa04152__35	0.414734550188199	DOWN	-0.816123624888284	0.484028707952563	AMPK signaling pathway: PFKFB1
hsa04910__26	0.415345182581395	DOWN	-0.815056796620456	0.484440470558933	Insulin signaling pathway: RPS6
hsa04610__23	0.420249332203065	UP	0.806522170477833	0.489856386606426	Complement and coagulation cascades: BDKRB1
hsa03320__25	0.422097122249358	DOWN	-0.80332168567435	0.491705203165867	PPAR signaling pathway: EHHADH
hsa04750__62	0.423331408474914	DOWN	-0.801188029138694	0.492227797505731	Inflammatory mediator regulation of TRP channels: TRPM8*
hsa04621__34 35	0.423331623613231	DOWN	-0.801188029138694	0.492227797505731	NOD-like receptor signaling pathway: CASP1 PYCARD
hsa04923__38	0.423331623613231	UP	0.801188029138694	0.492227797505731	Regulation of lipolysis in adipocytes: PDE3B
hsa04261__14 16	0.425187332639241	UP	0.797987544335211	0.49407977614665	Adrenergic signaling in cardiomyocytes: TNNI3 TPM1
hsa04973__5	0.426427107007458	DOWN	-0.795853887799555	0.495214174330663	Carbohydrate digestion and absorption: SLC2A5
hsa04750__51	0.427668899273885	DOWN	-0.793720231263899	0.496043124528167	Inflammatory mediator regulation of TRP channels: TRPV4
hsa04750__61	0.427668899273885	DOWN	-0.793720231263899	0.496043124528167	Inflammatory mediator regulation of TRP channels: TRPV4*
hsa04725__18	0.431407239584314	UP	0.787319261656933	0.500070452300386	Cholinergic synapse: ITPR1
hsa05200__220	0.43328344729767	UP	0.784118776853449	0.501935633460125	Pathways in cancer: CSF1R*
hsa04742__55	0.441465423018072	DOWN	-0.770250009371687	0.511098909335156	Taste transduction: P2RX3
hsa04115__22	0.442101253018076	DOWN	-0.76918318110386	0.511519861096653	p53 signaling pathway: STEAP3
hsa04210__85	0.445275185453761	UP	0.763849039764721	0.514875122133918	Apoptosis: FASLG*
hsa04066__46	0.44591152707928	UP	0.762782211496893	0.515293824958159	HIF-1 signaling pathway: ENO1
hsa04742__31	0.450380396250709	UP	0.755314413622098	0.520138146622669	Taste transduction: C00076*
hsa05161__78	0.451020870685854	UP	0.75424758535427	0.520557872247371	Hepatitis B: TNF
hsa04115__56	0.452303364846572	DOWN	-0.752113928818614	0.521717632011485	p53 signaling pathway: SESN3
hsa04115__55	0.452945383939361	DOWN	-0.751047100550787	0.522137654246662	p53 signaling pathway: SHISA5
hsa05215__43	0.45423067901057	DOWN	-0.748913444015131	0.523298250067971	Prostate cancer: C05981
hsa04062__40	0.454874525440788	UP	0.747846615747303	0.523718892955417	Chemokine signaling pathway: PRKACA
hsa04115__58	0.457453898591581	UP	0.743579302675992	0.525400901866492	p53 signaling pathway: CASP3
hsa05032__31	0.457453898591581	DOWN	-0.743579302675992	0.525400901866492	Morphine addiction: GABRR3
hsa05032__33	0.457453898591581	DOWN	-0.743579302675992	0.525400901866492	Morphine addiction: GABRR3*
hsa05032__55	0.457453898591581	DOWN	-0.743579302675992	0.525400901866492	Morphine addiction: GABRR3**
hsa05215__30	0.45810002265145	UP	0.742512474408164	0.525821589836332	Prostate cancer: TP53
hsa04014__37	0.460689632081362	DOWN	-0.738245161336853	0.528471195775872	Ras signaling pathway: FASLG
hsa04933__22	0.462637198645574	UP	0.735044676533369	0.530381510832845	AGE-RAGE signaling pathway in diabetic complications: EDN1
hsa04066__62	0.463938123427194	UP	0.732911019997714	0.531224700743265	HIF-1 signaling pathway: NPPA
hsa04917__75	0.463938123427194	UP	0.732911019997714	0.531224700743265	Prolactin signaling pathway: CCND1**
hsa05210__39	0.465893324366537	UP	0.72971053519423	0.533138584948066	Colorectal cancer: BAD
hsa04919__27	0.468507363437477	DOWN	-0.725443222122919	0.535477698235414	Thyroid hormone signaling pathway: GATA4
hsa05166__26	0.468507363437477	UP	0.725443222122919	0.535477698235414	HTLV-I infection: NFATC1
hsa04064__3	0.472443600220918	UP	0.719042252515952	0.539648343352648	NF-kappa B signaling pathway: BCL2
hsa04115__64	0.47310140589476	UP	0.717975424248124	0.540071410495902	p53 signaling pathway: PMAIP1
hsa04010__65	0.473759715237467	DOWN	-0.716908595980296	0.540166568526213	MAPK signaling pathway: ELK4
hsa05130__9	0.473759715237467	DOWN	-0.716908595980296	0.540166568526213	Pathogenic Escherichia coli infection: TLR4
hsa04660__56	0.477058804188486	UP	0.711574454641157	0.543598237155952	T cell receptor signaling pathway: CD3E
hsa04913__47	0.483694544623348	DOWN	-0.700906171962879	0.550491853026815	Ovarian steroidogenesis: INSR
hsa04913__51	0.483694544623348	DOWN	-0.700906171962879	0.550491853026815	Ovarian steroidogenesis: INSR*
hsa05166__83	0.486362796977538	DOWN	-0.696638858891568	0.553193520291038	HTLV-I infection: NFKB2
hsa04730__8	0.487031101330324	DOWN	-0.69557203062374	0.553283820676952	Long-term depression: GNA13*
hsa04933__35	0.487031101330324	UP	0.69557203062374	0.553283820676952	AGE-RAGE signaling pathway in diabetic complications: CCND1
hsa04115__19	0.49105132378084	DOWN	-0.689171061016773	0.557513859446646	p53 signaling pathway: RFWD2
hsa03320__45	0.492395348888672	DOWN	-0.687037404481117	0.558702210484188	PPAR signaling pathway: PDPK1
hsa04010__12	0.49643923192065	UP	0.68063643487415	0.562950704151419	MAPK signaling pathway: PLA2G4B
hsa04972__51	0.498467795013438	UP	0.677435950070667	0.564910124746833	Pancreatic secretion: CLCA1
hsa05161__29	0.502538108288073	UP	0.6710349804637	0.569179689857317	Hepatitis B: NFKB1
hsa05110__14	0.504579835700535	DOWN	-0.667834495660216	0.570460596438812	Vibrio cholerae infection: C00238*
hsa05110__15	0.504579835700535	DOWN	-0.667834495660216	0.570460596438812	Vibrio cholerae infection: C01330
hsa05110__16	0.504579835700535	DOWN	-0.667834495660216	0.570460596438812	Vibrio cholerae infection: C00698
hsa05160__55	0.505261382111225	DOWN	-0.666767667392389	0.570887634989171	Hepatitis C: MAPK14
hsa04970__32	0.506625928259539	DOWN	-0.664634010856733	0.57208540817288	Salivary secretion: RYR3
hsa04961__13	0.507308927131273	UP	0.663567182588905	0.572512597044842	Endocrine and other factor-regulated calcium reabsorption: ATP2B1
hsa04973__36	0.510045751100934	DOWN	-0.659299869517594	0.575255682064019	Carbohydrate digestion and absorption: SLC2A2
hsa05169__31	0.510731162021141	DOWN	-0.658233041249766	0.575683175427548	Epstein-Barr virus infection: MYC
hsa04725__43	0.512790279540566	DOWN	-0.655032556446283	0.577311525019008	Cholinergic synapse: CREB3
hsa05200__197	0.512790279540566	DOWN	-0.655032556446283	0.577311525019008	Pathways in cancer: CCND1**
hsa05321__81	0.518993490163149	UP	0.645431102035832	0.583945370069794	Inflammatory bowel disease (IBD): IL13
hsa04921__46	0.519685120246254	UP	0.644364273768004	0.584373633119516	Oxytocin signaling pathway: C00942*
hsa04976__36	0.520377128764162	DOWN	-0.643297445500177	0.584801809179342	Bile secretion: SLC10A1
hsa04024__110	0.521069805592965	DOWN	-0.642230617232349	0.585230223974406	cAMP signaling pathway: FOS
hsa04911__25	0.523844864031176	UP	0.637963304161038	0.587995519423286	Insulin secretion: PRKCA
hsa04540__14 31	0.525235229656853	UP	0.635829647625382	0.589204177029986	Gap junction: GJA1 TJP1
hsa05205__415	0.527324313018455	UP	0.632629162821898	0.591194739953268	Proteoglycans in cancer: MAPK1******
hsa04611__43	0.5322152705271	UP	0.625161364947104	0.596322297746226	Platelet activation: MYL12B
hsa04064__134	0.532915849370713	DOWN	-0.624094536679276	0.59647004438429	NF-kappa B signaling pathway: CCL21
hsa05200__66	0.533616894417239	DOWN	-0.623027708411448	0.59647004438429	Pathways in cancer: CCND1
hsa05205__129	0.533616894417239	UP	0.623027708411448	0.59647004438429	Proteoglycans in cancer: AKT3*
hsa05211__46	0.533616894417239	UP	0.623027708411448	0.59647004438429	Renal cell carcinoma: AKT3
hsa04213__62	0.543480200482989	DOWN	-0.608092112661858	0.607133945723862	Longevity regulating pathway - multiple species: CAT*
hsa05168__27	0.545605510859864	DOWN	-0.604891627858375	0.609146021928511	Herpes simplex infection: IRF3
hsa04919__91	0.54844565648415	UP	0.600624314787064	0.611953318606721	Thyroid hormone signaling pathway: PFKP
hsa04015__11	0.550580546517755	DOWN	-0.59742382998358	0.613242944224578	Rap1 signaling pathway: RAC1
hsa05200__224	0.550580546517755	UP	0.59742382998358	0.613242944224578	Pathways in cancer: MYC***
hsa05221__12	0.550580546517755	UP	0.59742382998358	0.613242944224578	Acute myeloid leukemia: MYC
hsa04662__35	0.553433414299299	UP	0.593156516912269	0.616055323144776	B cell receptor signaling pathway: CD79B
hsa05164__65 66	0.557009645153831	UP	0.58782237557313	0.619669107900561	Influenza A: DNAJC3 HSPA1A
hsa05231__17	0.559160787221276	UP	0.584621890769646	0.621694153366141	Choline metabolism in cancer: SLC44A3
hsa04010__119	0.559878726970165	DOWN	-0.583555062501819	0.622124262552891	MAPK signaling pathway: NFATC3
hsa04933__23	0.561315945985373	UP	0.581421405966163	0.622984443299773	AGE-RAGE signaling pathway in diabetic complications: F3
hsa05152__69	0.561315945985373	DOWN	-0.581421405966163	0.622984443299773	Tuberculosis: HLA-DMA
hsa04924__30	0.562035224169937	DOWN	-0.580354577698335	0.623414513704435	Renin secretion: PDE3A
hsa04390__96	0.563475115178469	UP	0.578220921162679	0.624274611686523	Hippo signaling pathway: FGF1
hsa04662__24	0.563475115178469	UP	0.578220921162679	0.624274611686523	B cell receptor signaling pathway: FOS
hsa04062__42	0.568528689992608	UP	0.570753123287885	0.629502303179794	Chemokine signaling pathway: PAK1
hsa04917__38	0.572877497053598	DOWN	-0.564352153680918	0.633570816341207	Prolactin signaling pathway: IRF1
hsa04972__21	0.572877497053598	UP	0.564352153680918	0.633570816341207	Pancreatic secretion: KCNQ1
hsa04620__23	0.578700343460916	DOWN	-0.555817527538295	0.638882459085229	Toll-like receptor signaling pathway: CD40
hsa04917__46	0.578700343460916	UP	0.555817527538295	0.638882459085229	Prolactin signaling pathway: GCK
hsa05216__15	0.578700343460916	DOWN	-0.555817527538295	0.638882459085229	Thyroid cancer: CCND1
hsa04666__49	0.579430150183199	UP	0.554750699270467	0.639312537988391	Fc gamma R-mediated phagocytosis: ARF6*
hsa04068__48	0.588221332157361	DOWN	-0.541948760056533	0.648631386809672	FoxO signaling pathway: FASLG
hsa04350__34	0.589692501335734	UP	0.539815103520878	0.649872263935393	TGF-beta signaling pathway: ROCK1
hsa04670__15	0.591165246899427	DOWN	-0.537681446985222	0.651113422581491	Leukocyte transendothelial migration: PECAM1
hsa04620__12	0.592639916217203	UP	0.535547790449567	0.652355244623389	Toll-like receptor signaling pathway: NFKB1
hsa05231__48	0.593377824068266	DOWN	-0.534480962181739	0.652785088655897	Choline metabolism in cancer: WAS
hsa05032__13	0.594854900532375	UP	0.532347305646083	0.654027125863272	Morphine addiction: PRKACA
hsa04724__65	0.597813701120602	DOWN	-0.528079992574772	0.65689587392141	Glutamatergic synapse: GRM3
hsa04380__72	0.599296172569751	DOWN	-0.525946336039116	0.658139981448605	Osteoclast differentiation: MAPK1
hsa05014__32 34	0.602265340850537	DOWN	-0.521679022967805	0.661014354823691	Amyotrophic lateral sclerosis (ALS): NEFM PRPH
hsa04022__71	0.603752398741167	UP	0.519545366432149	0.66225963644755	cGMP-PKG signaling pathway: PPIF
hsa04310__20	0.607477267922368	UP	0.51421122509301	0.665956701532164	Wnt signaling pathway: MAPK8
hsa04970__39	0.610464451698643	DOWN	-0.509943912021699	0.668841227254665	Salivary secretion: KCNN4
hsa04380__32	0.612709226468819	DOWN	-0.506743427218215	0.670518716677292	Osteoclast differentiation: AKT3
hsa05142__53	0.612709226468819	DOWN	-0.506743427218215	0.670518716677292	Chagas disease (American trypanosomiasis): AKT3
hsa05200__48	0.615707827828912	DOWN	-0.502476114146904	0.673408037538141	Pathways in cancer: MTOR
hsa04066__29	0.616458484410451	UP	0.501409285879076	0.673836819201418	HIF-1 signaling pathway: LDHA
hsa04210__61	0.624742045691181	DOWN	-0.48967417493297	0.682494362705657	Apoptosis: APAF1
hsa05131__12	0.627766118335538	UP	0.485406861861659	0.685399498171107	Shigellosis: ARPC5
hsa04350__32	0.630796454577456	DOWN	-0.481139548790348	0.688308094164367	TGF-beta signaling pathway: RPS6KB1
hsa04064__95	0.636114487307154	UP	0.473671750915553	0.693305755017484	NF-kappa B signaling pathway: BCL2L1**
hsa04724__26	0.636114487307154	UP	0.473671750915553	0.693305755017484	Glutamatergic synapse: PRKACA
hsa04350__41	0.636875748250033	DOWN	-0.472604922647725	0.693331130337087	TGF-beta signaling pathway: SMAD4***
hsa04380__38	0.636875748250033	UP	0.472604922647725	0.693331130337087	Osteoclast differentiation: FOS
hsa04062__53	0.639161829274066	UP	0.469404437844242	0.695416952638083	Chemokine signaling pathway: NFKB1
hsa04931__46	0.641451343396933	DOWN	-0.466203953040758	0.697504093890531	Insulin resistance: PIK3R5*
hsa05200__193	0.642215274516529	UP	0.46513712477293	0.697930885376841	Pathways in cancer: NOS2
hsa04621__6	0.643744272287448	UP	0.463003468237275	0.69878422162225	NOD-like receptor signaling pathway: NFKB1
hsa05168__9	0.643744272287448	UP	0.463003468237275	0.69878422162225	Herpes simplex infection: NFKB1
hsa04510__43	0.646040597517078	DOWN	-0.459802983433791	0.700871987722049	Focal adhesion: BAD
hsa05205__304	0.659116360553479	DOWN	-0.441666902880718	0.714644917184066	Proteoglycans in cancer: MAPK1*****
hsa04726__64	0.662208403376858	DOWN	-0.437399589809407	0.716756676235667	Serotonergic synapse: CASP3
hsa04910__12	0.662208403376858	UP	0.437399589809407	0.716756676235667	Insulin signaling pathway: FASN
hsa05161__68	0.662208403376858	UP	0.437399589809407	0.716756676235667	Hepatitis B: JUN
hsa04360__51	0.66375659127558	DOWN	-0.435265933273751	0.717193004604263	Axon guidance: FYN
hsa04620__29	0.66375659127558	UP	0.435265933273751	0.717193004604263	Toll-like receptor signaling pathway: CXCL8
hsa05205__324	0.66375659127558	UP	0.435265933273751	0.717193004604263	Proteoglycans in cancer: KDR*
hsa04360__122	0.666081565180929	UP	0.432065448470268	0.719291529295958	Axon guidance: CFL1**
hsa04115__54	0.668409752350669	DOWN	-0.428864963666784	0.721391111238889	p53 signaling pathway: PERP
hsa04062__44	0.673854575737246	DOWN	-0.42139716579199	0.726850027445628	Chemokine signaling pathway: MAPK1
hsa04933__24	0.676193332873481	UP	0.418196680988506	0.728954258444791	AGE-RAGE signaling pathway in diabetic complications: THBD
hsa04910__24	0.691077286034301	DOWN	-0.397926943899778	0.744572374116085	Insulin signaling pathway: ACACA
hsa04340__17	0.697380524369045	UP	0.389392317757155	0.750932954320594	Hedgehog signaling pathway: SMO
hsa05205__284	0.702913059780396	UP	0.38192451988236	0.756456838102729	Proteoglycans in cancer: PRKCA*
hsa05223__24	0.706874547366045	UP	0.376590378543221	0.760284644820148	Non-small cell lung cancer: STK4
hsa05215__9	0.708461375079579	DOWN	-0.374456722007565	0.761555448383598	Prostate cancer: CDKN1B
hsa05164__23	0.714821288742624	DOWN	-0.365922095864943	0.767952659546822	Influenza A: IRF3
hsa04210__114	0.718806347502549	DOWN	-0.360587954525804	0.771792643975594	Apoptosis: HRK
hsa04066__45	0.72199991515472	UP	0.356320641454492	0.774751538690989	HIF-1 signaling pathway: ALDOA
hsa04151__110	0.722799067230071	UP	0.355253813186665	0.774751538690989	PI3K-Akt signaling pathway: BCL2**
hsa04713__56	0.722799067230071	DOWN	-0.355253813186665	0.774751538690989	Circadian entrainment: KCNJ3
hsa04360__89	0.726799348831191	DOWN	-0.349919671847526	0.778151553534933	Axon guidance: CAMK2A
hsa04660__14	0.726799348831191	UP	0.349919671847526	0.778151553534933	T cell receptor signaling pathway: NFKB1
hsa05014__31 34	0.73000495167494	UP	0.345652358776214	0.781138555920964	Amyotrophic lateral sclerosis (ALS): NEFL PRPH
hsa05169__32	0.733215278978942	UP	0.341385045704903	0.784127210700872	Epstein-Barr virus infection: CR2
hsa04066__44	0.738844564704481	UP	0.333917247830108	0.7896979164276	HIF-1 signaling pathway: GAPDH
hsa05216__5	0.743680845933674	UP	0.327516278223141	0.794415184485147	Thyroid cancer: MAPK1
hsa04621__28	0.750144952566137	DOWN	-0.318981652080519	0.800864980608961	NOD-like receptor signaling pathway: CASP8
hsa04210__59	0.752573550810376	UP	0.315781167277035	0.803001534339975	Apoptosis: PMAIP1
hsa04912__46	0.756626651373274	DOWN	-0.310447025937896	0.806868035147776	GnRH signaling pathway: JUN
hsa04520__58	0.758442906254528	UP	0.302979228063101	0.808346126405138	Adherens junction: CDH1*
hsa04933__12	0.759061737177216	UP	0.307246541134413	0.808547054510198	AGE-RAGE signaling pathway in diabetic complications: EGR1
hsa04360__101 103	0.762312234489995	DOWN	-0.302979228063101	0.811549398644023	Axon guidance: DPYSL2 DPYSL5
hsa05200__191	0.76719583466928	UP	0.296578258456135	0.816285941870655	Pathways in cancer: CCND1*
hsa04024__113	0.769641119827318	UP	0.293377773652651	0.817902930677646	cAMP signaling pathway: PTCH1
hsa04390__88	0.770456725545202	UP	0.292310945384823	0.817902930677646	Hippo signaling pathway: ID1
hsa05014__54	0.770456725545202	UP	0.292310945384823	0.817902930677646	Amyotrophic lateral sclerosis (ALS): PPP3CA
hsa05200__212	0.770456725545202	DOWN	-0.292310945384823	0.817902930677646	Pathways in cancer: CCND1***
hsa03320__47	0.771272585181487	DOWN	-0.291244117116995	0.818306712341058	PPAR signaling pathway: PLTP
hsa04024__118	0.772905062809279	UP	0.28911046058134	0.819575966714805	cAMP signaling pathway: MYL9
hsa04933__52	0.776173027639002	UP	0.284843147510028	0.822577055236145	AGE-RAGE signaling pathway in diabetic complications: FOXO1
hsa04066__59	0.780263556159446	UP	0.279509006170889	0.826446010159865	HIF-1 signaling pathway: NOS2
hsa04976__41	0.781082288302354	DOWN	-0.278442177903062	0.826847109701478	Bile secretion: CYP7A1
hsa04270__65	0.782720746043793	UP	0.276308521367406	0.827649066376392	Vascular smooth muscle contraction: NPR2
hsa04390__78	0.782720804124986	DOWN	-0.276308521367406	0.827649066376392	Hippo signaling pathway: SOX2
hsa04530__1 5	0.783540370097609	DOWN	-0.275241693099578	0.828049693708328	Tight junction: IGSF5 IGSF5
hsa05200__5	0.789284009759387	DOWN	-0.267773895224783	0.832714572901678	Pathways in cancer: CASP3*
hsa05205__17	0.789284009759387	UP	0.267773895224783	0.832714572901678	Proteoglycans in cancer: AKT3
hsa05210__7	0.789284009759387	DOWN	-0.267773895224783	0.832714572901678	Colorectal cancer: CASP3*
hsa05200__186	0.794216273105871	DOWN	-0.261372925617816	0.836978338287118	Pathways in cancer: PTCH1*
hsa05223__22	0.794216273105871	UP	0.261372925617816	0.836978338287118	Non-small cell lung cancer: BAD*
hsa04912__33	0.797509039140518	UP	0.257105612546505	0.83997728954318	GnRH signaling pathway: ELK1
hsa04014__45	0.798332796453335	UP	0.256038784278677	0.840373851280569	Ras signaling pathway: RAB5A
hsa04022__43	0.799156778336793	UP	0.254971956010849	0.840770205204274	cGMP-PKG signaling pathway: MAPK1
hsa04151__102	0.805756612572281	UP	0.246437329868227	0.84676547820096	PI3K-Akt signaling pathway: C8orf44-SGK3
hsa05134__71	0.805756612572281	UP	0.246437329868227	0.84676547820096	Legionellosis: CXCL8
hsa04931__135	0.806582576045282	DOWN	-0.245370501600399	0.847159676014021	Insulin resistance: SREBF1**
hsa04910__57	0.807408755287377	DOWN	-0.244303673332571	0.847553659879878	Insulin signaling pathway: GCK
hsa04024__114	0.808235149414395	UP	0.243236845064743	0.847947429229284	cAMP signaling pathway: HHIP
hsa05161__66 67	0.809061757541444	UP	0.242170016796916	0.848340983493512	Hepatitis B: NFKB1 NFKBIA
hsa04912__26	0.812370312327115	UP	0.237902703725604	0.85125292427637	GnRH signaling pathway: PLD1
hsa04742__18	0.813197977155978	DOWN	-0.236835875457776	0.85125292427637	Taste transduction: PDE1A
hsa04912__19	0.813197977155978	UP	0.236835875457776	0.85125292427637	GnRH signaling pathway: MAPK7
hsa04310__36	0.815682220136928	UP	0.233635390654293	0.853378002025216	Wnt signaling pathway: MYC
hsa05169__64	0.816510714326893	UP	0.232568562386465	0.853769411363513	Epstein-Barr virus infection: NFKB2
hsa04520__44 49	0.822315866763785	DOWN	-0.22510076451167	0.859361242296525	Adherens junction: ACTB VCL
hsa04510__47	0.827299478414356	DOWN	-0.218699794904703	0.864088782624	Focal adhesion: CCND1
hsa04912__20	0.830625767277188	DOWN	-0.214432481833392	0.867081009285464	GnRH signaling pathway: PLA2G4B
hsa04115__24	0.833955093672436	DOWN	-0.210165168762081	0.870073082182403	p53 signaling pathway: SERPINB5
hsa04064__94	0.838120934962261	DOWN	-0.204831027422942	0.873934093670415	NF-kappa B signaling pathway: BCL2L1*
hsa05132__6	0.839788549660217	DOWN	-0.202697370887286	0.875187290522212	Salmonella infection: NFKB1
hsa05016__22 9	0.845630819140962	DOWN	-0.195229573012491	0.880787311067554	Huntington's disease: DLG4 HTT
hsa04024__116	0.84646613030396	DOWN	-0.194162744744664	0.881168896864898	cAMP signaling pathway: ACOX1
hsa04924__58	0.848137269416732	UP	0.192029088209008	0.881931338812418	Renin secretion: PPP3CA
hsa05031__59	0.848137269416732	UP	0.192029088209008	0.881931338812418	Amphetamine addiction: PPP3CA
hsa04350__50	0.848973095535072	UP	0.19096225994118	0.882312193866372	TGF-beta signaling pathway: AMHR2
hsa04010__67	0.851481589137207	UP	0.187761775137697	0.883941384524206	MAPK signaling pathway: ELK1
hsa05014__33 34	0.851481589137207	DOWN	-0.187761775137697	0.883941384524206	Amyotrophic lateral sclerosis (ALS): NEFH PRPH
hsa05164__24	0.864046113882994	DOWN	-0.171759351120279	0.896489590273962	Influenza A: IRF7
hsa04068__72	0.866563255790354	UP	0.168558866316796	0.898605053879733	FoxO signaling pathway: SMAD2
hsa04970__45	0.868242087636935	DOWN	-0.16642520978114	0.899353315167508	Salivary secretion: KCNMA1
hsa04725__54	0.868242104158521	UP	0.16642520978114	0.899353315167508	Cholinergic synapse: CHRM1*
hsa04210__86	0.874963366648308	DOWN	-0.157890583638518	0.905816069384116	Apoptosis: BCL2L11
hsa04014__58 59	0.881693661699307	UP	0.149355957495895	0.912281051945483	Ras signaling pathway: STK4 STK4
hsa05020__49	0.884219753400709	UP	0.146155472692412	0.914255957193126	Prion diseases: BAX
hsa04151__101	0.885062046904894	UP	0.145088644424584	0.914255957193126	PI3K-Akt signaling pathway: PKN3
hsa04623__25	0.885062046904894	UP	0.145088644424584	0.914255957193126	Cytosolic DNA-sensing pathway: NFKB1*
hsa04390__12	0.886747022688792	DOWN	-0.142954987888928	0.915493217380352	Hippo signaling pathway: CTGF
hsa04961__26	0.895179432697922	UP	0.13228670521065	0.923184497277385	Endocrine and other factor-regulated calcium reabsorption: TRPV5*
hsa05220__50	0.895179432697922	DOWN	-0.13228670521065	0.923184497277385	Chronic myeloid leukemia: MAPK1
hsa04726__45	0.89686733790102	DOWN	-0.130153048674994	0.924417843069674	Serotonergic synapse: TRPC1
hsa04950__11	0.902778769491303	UP	0.1226852508002	0.929491127602278	Maturity onset diabetes of the young: HNF4G
hsa05162__58	0.902778769491303	DOWN	-0.1226852508002	0.929491127602278	Measles: STAT3
hsa04064__25	0.906159156118258	DOWN	-0.118417937728888	0.932460599313366	NF-kappa B signaling pathway: NFKB2
hsa05134__68	0.907849991075717	UP	0.116284281193233	0.93368918075056	Legionellosis: TNF
hsa04972__39	0.911232906316426	UP	0.112016968121921	0.936655706219127	Pancreatic secretion: KCNMA1*
hsa05161__69	0.912078889027643	DOWN	-0.110950139854093	0.93701270228701	Hepatitis B: SMAD4
hsa04064__133	0.91715684482555	UP	0.104549170247127	0.941714596408311	NF-kappa B signaling pathway: CXCL2
hsa04380__48	0.923085386630571	DOWN	-0.0970813723723318	0.946767162379281	Osteoclast differentiation: NFATC1
hsa04380__51	0.923085386630571	DOWN	-0.0970813723723318	0.946767162379281	Osteoclast differentiation: FOS*
hsa04390__77	0.924780055437533	UP	0.0949477158366761	0.94798784733613	Hippo signaling pathway: CCND1
hsa04062__43	0.928170409666328	DOWN	-0.0906804027653649	0.950944492782459	Chemokine signaling pathway: STAT1
hsa05132__86	0.929018204439455	DOWN	-0.089613574497537	0.951294390267976	Salmonella infection: MYH9
hsa05134__7	0.929866079785081	UP	0.0885467462297092	0.951643989061094	Legionellosis: IL18
hsa04911__56	0.935803382777435	DOWN	-0.0810789483549145	0.957024937669014	Insulin secretion: CAMK2A*
hsa04064__116	0.93665186821358	DOWN	-0.0800121200870866	0.957024937669014	NF-kappa B signaling pathway: GADD45B
hsa05210__9 11	0.93665186821358	DOWN	-0.0800121200870866	0.957024937669014	Colorectal cancer: SMAD2 SMAD4
hsa04620__46	0.94174425810196	UP	0.0736111504801197	0.961705141833469	Toll-like receptor signaling pathway: TNF
hsa04310__35	0.942593226998788	DOWN	-0.0725443222122919	0.962049252325216	Wnt signaling pathway: JUN
hsa04211__39	0.94853778167075	DOWN	-0.0650765243374971	0.967590929293887	Longevity regulating pathway - mammal: TP53*
hsa04014__41	0.951086344539371	DOWN	-0.0618760395340137	0.969664265539597	Ras signaling pathway: RAC1*
hsa05110__13	0.953635388270061	DOWN	-0.0586755547305302	0.971735843036575	Vibrio cholerae infection: C00238
hsa04931__137	0.958734931451743	UP	0.0522745851235633	0.976402675445976	Insulin resistance: MLXIP*
hsa04115__27	0.962135565195924	UP	0.048007272052252	0.978804941528501	p53 signaling pathway: THBS1
hsa04972__18	0.962135565195924	UP	0.048007272052252	0.978804941528501	Pancreatic secretion: PRKCA
hsa04071__1	0.964686496032662	DOWN	-0.0448067872487685	0.98086900760031	Sphingolipid signaling pathway: MAPK1
hsa04014__69	0.968938837840731	DOWN	-0.0394726459096294	0.984659857383847	Ras signaling pathway: PLCE1*
hsa05200__96	0.972341353086612	UP	0.0352053328383181	0.987583460783646	Pathways in cancer: C00416
hsa04920__3	0.978296928977131	UP	0.0277375349635234	0.993095585925462	Adipocytokine signaling pathway: C15493
hsa05161__31	0.980849708414362	UP	0.0245370501600399	0.995149353191461	Hepatitis B: ELK1
hsa04730__30	0.983402683971828	DOWN	-0.0213365653565564	0.996663237962818	Long-term depression: C00025*
hsa04740__42	0.983402683971828	UP	0.0213365653565564	0.996663237962818	Olfactory transduction: PDE2A
hsa05200__190	0.98680691128157	DOWN	-0.0170692522852452	0.999574224419445	Pathways in cancer: MYC*
hsa04728__64	0.989360242799431	DOWN	-0.0138687674817617	1	Dopaminergic synapse: SCN1A
hsa04152__38	0.997020786608954	UP	0.00426731307131129	1	AMPK signaling pathway: PFKL
hsa05200__185	0.997020786608954	UP	0.00426731307131129	1	Pathways in cancer: HHIP
hsa04152__33	1	0	0	1	AMPK signaling pathway: CPT1C
hsa04152__41	1	0	0	1	AMPK signaling pathway: FBP1
hsa04211__2	1	0	0	1	Longevity regulating pathway - mammal: RPS6KB1
hsa04911__41	1	0	0	1	Insulin secretion: ABCC8
hsa04911__35	1	0	0	1	Insulin secretion: TRPM4
hsa04922__67	1	0	0	1	Glucagon signaling pathway: FBP1
hsa04922__60	1	0	0	1	Glucagon signaling pathway: CPT1C*
hsa04924__34	1	0	0	1	Renin secretion: REN
hsa04924__47	1	0	0	1	Renin secretion: KCNMA1
hsa04931__151	1	0	0	1	Insulin resistance: CPT1A
hsa04931__29	1	0	0	1	Insulin resistance: CPT1B
hsa04960__15	1	0	0	1	Aldosterone-regulated sodium reabsorption: C00762
hsa05030__13	1	0	0	1	Cocaine addiction: SLC6A3
hsa05031__15	1	0	0	1	Amphetamine addiction: MAOA
hsa05031__77	1	0	0	1	Amphetamine addiction: MAOA*
hsa05034__7	1	0	0	1	Alcoholism: GRIN3A
hsa05034__75	1	0	0	1	Alcoholism: SLC29A1
hsa05140__37	1	0	0	1	Leishmaniasis: ELK1
hsa05140__55	1	0	0	1	Leishmaniasis: JUN
hsa05140__41 57	1	0	0	1	Leishmaniasis: NOS2 CYBA
hsa05211__12	1	0	0	1	Renal cell carcinoma: EGLN2