p.value	UP.DOWN	statistic	FDRp.value	path.name
hsa04211__43 59 60 61	6.19727389928484e-20	UP	9.14201676810075	2.00284941303531e-17	Longevity regulating pathway - mammal: ULK3 RB1CC1 ATG13 ATG101
hsa04750__8	6.19727389928484e-20	DOWN	-9.14201676810075	2.00284941303531e-17	Inflammatory mediator regulation of TRP channels: ASIC2
hsa04530__11 24 23	6.20322298083992e-20	DOWN	-9.14201676810075	2.00284941303531e-17	Tight junction: TJP1 YBX3 CDK4
hsa05200__168	6.66215778052172e-20	UP	9.13429547015472	2.00284941303531e-17	Pathways in cancer: E2F1
hsa04960__3	8.24999847789783e-20	DOWN	-9.11113157631663	2.00284941303531e-17	Aldosterone-regulated sodium reabsorption: SCNN1A
hsa04066__53	1.02108622737193e-19	DOWN	-9.08796768247853	2.00284941303531e-17	HIF-1 signaling pathway: EGF*
hsa04916__7	1.09617712801014e-19	DOWN	-9.0802463845325	2.00284941303531e-17	Melanogenesis: TYRP1
hsa04962__10	1.17672086803919e-19	DOWN	-9.07252508658647	2.00284941303531e-17	Vasopressin-regulated water reabsorption: AQP2
hsa05120__20	1.17672086803919e-19	UP	9.07252508658647	2.00284941303531e-17	Epithelial cell signaling in Helicobacter pylori infection: CXCL8
hsa05219__12	1.35236329774245e-19	DOWN	-9.05708249069441	2.00284941303531e-17	Bladder cancer: ERBB2
hsa04919__28	1.42122300163292e-19	DOWN	-9.05193495873039	2.00284941303531e-17	Thyroid hormone signaling pathway: RCAN1
hsa04550__101	1.48981032356355e-19	DOWN	-9.04678742676637	2.00284941303531e-17	Signaling pathways regulating pluripotency of stem cells: ESRRB
hsa04810__82 83	1.52532043670883e-19	UP	9.04421366078436	2.00284941303531e-17	Regulation of actin cytoskeleton: ACTB ARPC5
hsa04022__65	1.5616667180663e-19	DOWN	-9.04163989480235	2.00284941303531e-17	cGMP-PKG signaling pathway: PDE2A
hsa04066__56	1.59886861072537e-19	DOWN	-9.03906612882034	2.00284941303531e-17	HIF-1 signaling pathway: TEK
hsa04917__34	1.92977095962415e-19	DOWN	-9.01847600096425	2.26627477070861e-17	Prolactin signaling pathway: ELF5
hsa03460__7	2.43986645742187e-19	UP	8.99273834114415	2.45903933035174e-17	Fanconi anemia pathway: FANCI
hsa04110__59 15 16 17 18 19 20	2.55684257637003e-19	UP	8.98759080918013	2.45903933035174e-17	Cell cycle: CDC45 MCM7 MCM6 MCM5 MCM4 MCM3 MCM2
hsa05212__34	2.55684257637003e-19	UP	8.98759080918013	2.45903933035174e-17	Pancreatic cancer: E2F1
hsa05219__10	2.61739151713863e-19	DOWN	-8.98501704319812	2.45903933035174e-17	Bladder cancer: EGFR
hsa05131__38	2.80766786789367e-19	UP	8.97729574525209	2.51219424941534e-17	Shigellosis: CXCL8
hsa04910__46	3.08277605172551e-19	DOWN	-8.96700068132405	2.58559794654075e-17	Insulin signaling pathway: FBP1
hsa05214__35	3.2301525838578e-19	UP	8.96185314936003	2.58559794654075e-17	Glioma: E2F1
hsa04933__43	3.46436229655892e-19	UP	8.954131851414	2.58559794654075e-17	AGE-RAGE signaling pathway in diabetic complications: CASP3
hsa04662__27	3.54610048909626e-19	DOWN	-8.95155808543199	2.58559794654075e-17	B cell receptor signaling pathway: NFATC1
hsa04925__18	3.62974344848452e-19	DOWN	-8.94898431944998	2.58559794654075e-17	Aldosterone synthesis and secretion: PDE2A
hsa04152__78	3.71533499502928e-19	UP	8.94641055346796	2.58559794654075e-17	AMPK signaling pathway: CCNA2
hsa04960__13	3.89254412679359e-19	DOWN	-8.94126302150394	2.6121751479447e-17	Aldosterone-regulated sodium reabsorption: FXYD4
hsa05160__56	4.27238672691325e-19	DOWN	-8.9309679575759	2.73891293776314e-17	Hepatitis C: MAPK1
hsa04210__60	4.37293177929187e-19	UP	8.92839419159389	2.73891293776314e-17	Apoptosis: BBC3
hsa05223__28	4.58108618420678e-19	UP	8.92324665962987	2.77672933552405e-17	Non-small cell lung cancer: RB1
hsa04960__27	4.79902320102293e-19	DOWN	-8.91809912766585	2.81792643585065e-17	Aldosterone-regulated sodium reabsorption: KCNJ1
hsa04115__21	5.02719653618548e-19	UP	8.91295159570183	2.86245523984622e-17	p53 signaling pathway: DDB2
hsa04115__38	5.26608065115349e-19	UP	8.90780406373781	2.91028398338747e-17	p53 signaling pathway: GTSE1
hsa04390__90	5.51617169835748e-19	UP	8.90265653177379	2.96139617748963e-17	Hippo signaling pathway: BBC3
hsa04961__26	5.91346263666319e-19	DOWN	-8.89493523382776	3.00308007953787e-17	Endocrine and other factor-regulated calcium reabsorption: TRPV5*
hsa05150__48	5.91346263666319e-19	UP	8.89493523382776	3.00308007953787e-17	Staphylococcus aureus infection: C3AR1
hsa05160__71	7.11641035488903e-19	DOWN	-8.87434510597168	3.51887764653592e-17	Hepatitis C: MAPK8
hsa04922__59	7.98786180645261e-19	DOWN	-8.86147627606162	3.83992476257212e-17	Glucagon signaling pathway: CPT1C
hsa05166__120	8.17440077184059e-19	UP	8.85890251007961	3.83992476257212e-17	HTLV-I infection: E2F1
hsa03320__37	8.56048095153272e-19	DOWN	-8.85375497811559	3.91754782342897e-17	PPAR signaling pathway: HMGCS2
hsa04960__4	9.17347550674607e-19	DOWN	-8.84603368016956	3.91754782342897e-17	Aldosterone-regulated sodium reabsorption: ATP1B4
hsa05218__21	9.17360852745475e-19	UP	8.84603368016956	3.91754782342897e-17	Melanoma: RB1
hsa05220__40	9.17360852745475e-19	UP	8.84603368016956	3.91754782342897e-17	Chronic myeloid leukemia: RB1
hsa04662__32 51	1.00590381816331e-18	DOWN	-8.83573861624152	4.20020727628637e-17	B cell receptor signaling pathway: BLNK GRB2
hsa05205__304	1.18161354613655e-18	DOWN	-8.81772225436745	4.82663446345778e-17	Proteoglycans in cancer: MAPK1*****
hsa03460__27	1.20907299270193e-18	UP	8.81514848838544	4.83371947507855e-17	Fanconi anemia pathway: BRCA1
hsa04919__100	1.26589624466061e-18	DOWN	-8.81000095642142	4.86769568203787e-17	Thyroid hormone signaling pathway: CTNNB1*
hsa04919__11	1.29528889889246e-18	DOWN	-8.80742719043941	4.86769568203787e-17	Thyroid hormone signaling pathway: CTNNB1
hsa05010__12	1.29528889889246e-18	UP	8.80742719043941	4.86769568203787e-17	Alzheimer's disease: CASP3
hsa05016__52	1.35611081745921e-18	UP	8.80227965847538	4.99633769805071e-17	Huntington's disease: CASP3
hsa04961__17	1.38757090593011e-18	DOWN	-8.79970589249337	5.01393410046669e-17	Endocrine and other factor-regulated calcium reabsorption: CALB1
hsa05110__14	1.5560106850675e-18	DOWN	-8.78683706258332	5.22097156650328e-17	Vibrio cholerae infection: C00238*
hsa05110__15	1.5560106850675e-18	DOWN	-8.78683706258332	5.22097156650328e-17	Vibrio cholerae infection: C01330
hsa05110__16	1.5560106850675e-18	DOWN	-8.78683706258332	5.22097156650328e-17	Vibrio cholerae infection: C00698
hsa05166__132 136	1.5560106850675e-18	UP	8.78683706258332	5.22097156650328e-17	HTLV-I infection: CREBBP TP53
hsa04010__117	1.62890454510193e-18	UP	8.7816895306193	5.36966954429215e-17	MAPK signaling pathway: JUND
hsa04924__31	1.74453754045945e-18	DOWN	-8.77396823267327	5.55614635979686e-17	Renin secretion: C02135
hsa04961__5	1.74461221515708e-18	DOWN	-8.77396823267327	5.55614635979686e-17	Endocrine and other factor-regulated calcium reabsorption: TRPV5
hsa04114__80	1.82622190375763e-18	UP	8.76882070070925	5.62536222485342e-17	Oocyte meiosis: CDC25C*
hsa05150__13	1.82622190375763e-18	UP	8.76882070070925	5.62536222485342e-17	Staphylococcus aureus infection: C5AR1
hsa04610__23	1.91159910055319e-18	DOWN	-8.76367316874523	5.79337856441846e-17	Complement and coagulation cascades: BDKRB1
hsa04012__8	2.04710635834243e-18	DOWN	-8.7559518707992	6.01017632394597e-17	ErbB signaling pathway: STAT5A
hsa04976__95 96	2.04710635834243e-18	UP	8.7559518707992	6.01017632394597e-17	Bile secretion: SLC51A SLC51B
hsa03460__16 49	2.242635738956e-18	UP	8.74565680687116	6.48294238999742e-17	Fanconi anemia pathway: FANCM C19orf40
hsa04010__66	2.40127913504689e-18	UP	8.73793550892513	6.50129736756994e-17	MAPK signaling pathway: TP53
hsa04010__67	2.45658389088593e-18	UP	8.73536174294312	6.50129736756994e-17	MAPK signaling pathway: ELK1
hsa04068__52	2.45658389088593e-18	DOWN	-8.73536174294312	6.50129736756994e-17	FoxO signaling pathway: CAT
hsa04210__74	2.45658389088593e-18	UP	8.73536174294312	6.50129736756994e-17	Apoptosis: BAX*
hsa05150__1 2 3	2.45658389088593e-18	UP	8.73536174294312	6.50129736756994e-17	Staphylococcus aureus infection: CFD C3 CFB
hsa05166__65	2.45658389088593e-18	UP	8.73536174294312	6.50129736756994e-17	HTLV-I infection: PTTG2
hsa04742__47	3.2265222890514e-18	DOWN	-8.70447655115899	8.30050855880698e-17	Taste transduction: GABRA1
hsa04014__70	3.22683953387533e-18	UP	8.70447655115899	8.30050855880698e-17	Ras signaling pathway: RIN1*
hsa04961__20	3.26896026264884e-18	DOWN	-8.70190278517698	8.30050855880698e-17	Endocrine and other factor-regulated calcium reabsorption: CALB1*
hsa05150__40	3.61417354195688e-18	UP	8.69160772124894	9.05470944711598e-17	Staphylococcus aureus infection: FCGR1A
hsa03460__48	3.69697747285496e-18	UP	8.68903395526693	9.14029035722957e-17	Fanconi anemia pathway: RAD51
hsa05110__13	3.86819012851013e-18	DOWN	-8.68388642330291	9.31850110713142e-17	Vibrio cholerae infection: C00238
hsa04550__47	3.86824420625998e-18	DOWN	-8.68388642330291	9.31850110713142e-17	Signaling pathways regulating pluripotency of stem cells: CTNNB1*
hsa04261__73	4.13993185037512e-18	DOWN	-8.67616512535688	9.72366493356856e-17	Adrenergic signaling in cardiomyocytes: KCNE1
hsa04932__55	4.13993185037512e-18	UP	8.67616512535688	9.72366493356856e-17	Non-alcoholic fatty liver disease (NAFLD): CASP3
hsa04530__11 33	4.23461513387841e-18	DOWN	-8.67359135937487	9.82326152661423e-17	Tight junction: TJP1 CGN
hsa04010__118	4.43044069614908e-18	UP	8.66844382741085	1.00298771904387e-16	MAPK signaling pathway: JUN
hsa05166__64	4.43044069614908e-18	UP	8.66844382741085	1.00298771904387e-16	HTLV-I infection: CCNB2
hsa04730__20	4.74105606624114e-18	DOWN	-8.66072252946482	1.06052908910323e-16	Long-term depression: C00025
hsa04620__48	4.8492971416899e-18	UP	8.65814876348281	1.07197992108651e-16	Toll-like receptor signaling pathway: CD80
hsa03460__25 40	4.95997697445183e-18	UP	8.6555749975008	1.08369729476686e-16	Fanconi anemia pathway: MLH1 PMS2
hsa04115__39	5.18887088905164e-18	UP	8.65042746553677	1.1206768276469e-16	p53 signaling pathway: BAX
hsa03460__28	5.42818579206353e-18	UP	8.64527993357275	1.15904103446447e-16	Fanconi anemia pathway: RAD51C
hsa04915__40	5.67838949623851e-18	DOWN	-8.64013240160873	1.19884200712721e-16	Estrogen signaling pathway: CREB3**
hsa04933__19	5.807726474715e-18	DOWN	-8.63755863562672	1.21252422733216e-16	AGE-RAGE signaling pathway in diabetic complications: TGFBR2
hsa04390__75	5.93997050959352e-18	DOWN	-8.63498486964471	1.22650599862926e-16	Hippo signaling pathway: NKD1
hsa04666__20	6.21343893704269e-18	DOWN	-8.62983733768069	1.26902736551122e-16	Fc gamma R-mediated phagocytosis: PLA2G4B
hsa04115__49	6.35479647482031e-18	UP	8.62726357169868	1.28394221249327e-16	p53 signaling pathway: MDM2*
hsa04730__30	6.49932742068673e-18	DOWN	-8.62468980571667	1.29917406632663e-16	Long-term depression: C00025*
hsa04210__56	7.43719857538657e-18	UP	8.60924720982461	1.47099959191067e-16	Apoptosis: BAX
hsa04540__22	7.95447853978e-18	DOWN	-8.60152591187858	1.54097840117838e-16	Gap junction: C00547
hsa04072__27	7.95502421044717e-18	DOWN	-8.60152591187858	1.54097840117838e-16	Phospholipase D signaling pathway: C01245
hsa04713__61	8.13541790225696e-18	DOWN	-8.59895214589657	1.55984186105519e-16	Circadian entrainment: FOS
hsa03320__20	8.50840328371665e-18	DOWN	-8.59380461393255	1.61487775455592e-16	PPAR signaling pathway: SCP2
hsa03320__22	8.89825614496641e-18	DOWN	-8.58865708196853	1.67198232963919e-16	PPAR signaling pathway: ACADM
hsa05200__129 130	9.30572848537224e-18	DOWN	-8.58350955000451	1.7142611592171e-16	Pathways in cancer: CTBP1 HDAC1
hsa05220__12 13	9.30572848537224e-18	DOWN	-8.58350955000451	1.7142611592171e-16	Chronic myeloid leukemia: HDAC1 CTBP1
hsa04919__32	9.73160533624946e-18	DOWN	-8.57836201804048	1.77530936182648e-16	Thyroid hormone signaling pathway: PLN
hsa04110__10 11 12 13 14 9 15 16 17 18 19 20	9.95170015791237e-18	UP	8.57578825205847	1.7980042881459e-16	Cell cycle: ORC3 ORC5 ORC4 ORC2 ORC1 ORC6 MCM7 MCM6 MCM5 MCM4 MCM3 MCM2
hsa04014__27	1.13792698588327e-17	UP	8.56034565616641	2.03634743473777e-16	Ras signaling pathway: ABL1
hsa04211__38	1.18986414369509e-17	UP	8.55519812420239	2.10920257170101e-16	Longevity regulating pathway - mammal: BAX
hsa04621__4 7 8	1.39074765246651e-17	UP	8.53718176232832	2.44225685886409e-16	NOD-like receptor signaling pathway: IKBKG CHUK IKBKB
hsa05205__324	1.42205267096172e-17	DOWN	-8.53460799634631	2.47410830438618e-16	Proteoglycans in cancer: KDR*
hsa04620__22	1.45405283981578e-17	UP	8.5320342303643	2.50657365689345e-16	Toll-like receptor signaling pathway: CD86
hsa04066__60	1.5201998354546e-17	DOWN	-8.52688669840028	2.59677771892655e-16	HIF-1 signaling pathway: NOS3
hsa04931__144	1.62502526597574e-17	DOWN	-8.51916540045425	2.75083105834993e-16	Insulin resistance: C00533*
hsa04210__64	1.69883894313935e-17	UP	8.51401786849023	2.85010569121324e-16	Apoptosis: TNFRSF10D*
hsa05142__49	1.98419823991878e-17	DOWN	-8.49600150661615	3.2420073850499e-16	Chagas disease (American trypanosomiasis): ADCY1
hsa05162__23	1.98419823991878e-17	UP	8.49600150661615	3.2420073850499e-16	Measles: IRF3
hsa05200__201	1.98419823991878e-17	DOWN	-8.49600150661615	3.2420073850499e-16	Pathways in cancer: PDGFB
hsa04115__17	2.07408250859013e-17	UP	8.49085397465213	3.35965606348349e-16	p53 signaling pathway: TP73
hsa05217__22	2.12051941675051e-17	DOWN	-8.48828020867012	3.40551793510616e-16	Basal cell carcinoma: LEF1
hsa04922__51	2.21649207442611e-17	DOWN	-8.4831326767061	3.52948187105649e-16	Glucagon signaling pathway: G6PC
hsa05205__369	2.5308698591881e-17	DOWN	-8.46769008081404	3.99622223984407e-16	Proteoglycans in cancer: HOXD10
hsa05168__122	2.58738156548437e-17	UP	8.46511631483203	4.01792558805383e-16	Herpes simplex infection: CASP3
hsa05200__222	2.58738156548437e-17	UP	8.46511631483203	4.01792558805383e-16	Pathways in cancer: CASP9*
hsa04014__45	2.64513782376459e-17	UP	8.46254254885002	4.06490180757903e-16	Ras signaling pathway: RAB5A
hsa04621__28	2.70416565166248e-17	UP	8.45996878286801	4.06490180757903e-16	NOD-like receptor signaling pathway: CASP8
hsa04932__31 133	2.70416565166248e-17	DOWN	-8.45996878286801	4.06490180757903e-16	Non-alcoholic fatty liver disease (NAFLD): PPARA RXRA
hsa05160__7	2.70416565166248e-17	UP	8.45996878286801	4.06490180757903e-16	Hepatitis C: IRF3
hsa04115__58	2.82614698797058e-17	UP	8.45482125090399	4.21454777015613e-16	p53 signaling pathway: CASP3
hsa04530__22 33	3.01936508633894e-17	DOWN	-8.44709995295796	4.4672338560873e-16	Tight junction: MYL12B CGN
hsa04360__122	3.08662292436293e-17	DOWN	-8.44452618697595	4.53106599599839e-16	Axon guidance: CFL1**
hsa05211__23	3.15535833274711e-17	DOWN	-8.44195242099394	4.59606070328048e-16	Renal cell carcinoma: PDGFB
hsa04972__42	3.29739052323101e-17	DOWN	-8.43680488902992	4.76599753319312e-16	Pancreatic secretion: CFTR
hsa04623__9	4.01862496717056e-17	UP	8.41364099519182	5.76411932314006e-16	Cytosolic DNA-sensing pathway: IKBKE
hsa04962__22	4.19891139277745e-17	DOWN	-8.4084934632278	5.97708674774912e-16	Vasopressin-regulated water reabsorption: ARHGDIA
hsa04620__23	4.58375189742105e-17	UP	8.39819839929976	6.47584196635651e-16	Toll-like receptor signaling pathway: CD40
hsa04068__59	4.78901573323182e-17	DOWN	-8.39305086733574	6.71534370353925e-16	FoxO signaling pathway: S1PR1
hsa04976__16	4.89502129668884e-17	DOWN	-8.39047710135373	6.81314445665062e-16	Bile secretion: CFTR
hsa04012__21	5.22712055272798e-17	UP	8.3827558034077	7.22188199895285e-16	ErbB signaling pathway: GSK3B
hsa05034__84	5.46076651745909e-17	DOWN	-8.37760827144368	7.48962064693842e-16	Alcoholism: FOSB
hsa04972__21	5.70470700336249e-17	DOWN	-8.37246073947966	7.76749598501314e-16	Pancreatic secretion: KCNQ1
hsa04726__64	6.50286017520493e-17	UP	8.3570181435876	8.79055702820868e-16	Serotonergic synapse: CASP3
hsa05161__213	6.64619365997609e-17	UP	8.35444437760559	8.92014134792505e-16	Hepatitis B: E2F1
hsa05215__25	6.79264204376608e-17	DOWN	-8.35187061162357	9.05203858172799e-16	Prostate cancer: FOXO1
hsa04115__11 12	7.74058060137873e-17	UP	8.33642801573151	1.01710146503431e-15	p53 signaling pathway: CDK2 CCNE1
hsa05164__23	7.74058060137873e-17	UP	8.33642801573151	1.01710146503431e-15	Influenza A: IRF3
hsa05152__88 89	7.91078175309214e-17	UP	8.3338542497495	1.03224714680973e-15	Tuberculosis: ITGAX ITGB2
hsa04012__23	8.26233156245391e-17	DOWN	-8.32870671778548	1.0633507538254e-15	ErbB signaling pathway: RPS6KB1
hsa04622__9 35	8.26233156245391e-17	UP	8.32870671778548	1.0633507538254e-15	RIG-I-like receptor signaling pathway: IRF3 PIN1
hsa04742__34	8.44383948622907e-17	DOWN	-8.32613295180347	1.07931798602887e-15	Taste transduction: GRM1
hsa04390__79	8.6292783966079e-17	DOWN	-8.32355918582146	1.09556852075853e-15	Hippo signaling pathway: SNAI2
hsa03460__16 34	8.81873217347576e-17	UP	8.32098541983945	1.1046931835974e-15	Fanconi anemia pathway: FANCM STRA13
hsa04931__124	8.81873217347576e-17	DOWN	-8.32098541983945	1.1046931835974e-15	Insulin resistance: FOXO1*
hsa04020__42	1.02647502004869e-16	DOWN	-8.30296905796538	1.26891221228388e-15	Calcium signaling pathway: MYLK4
hsa05152__97	1.02647502004869e-16	UP	8.30296905796538	1.26891221228388e-15	Tuberculosis: IL18
hsa05031__8	1.07177204603615e-16	DOWN	-8.29782152600136	1.30788493111326e-15	Amphetamine addiction: DRD1
hsa04922__50	1.07192272161491e-16	DOWN	-8.29782152600136	1.30788493111326e-15	Glucagon signaling pathway: PCK1
hsa04270__10 3 71	1.19440478775161e-16	DOWN	-8.28495269609131	1.44792683624856e-15	Vascular smooth muscle contraction: ACTA2 MYL9 MYH11
hsa04210__58	1.22050800599164e-16	UP	8.2823789301093	1.46072263901802e-15	Apoptosis: BID*
hsa04520__18	1.22050800599164e-16	DOWN	-8.2823789301093	1.46072263901802e-15	Adherens junction: SNAI2
hsa05166__136 139	1.24717354858004e-16	UP	8.27980516412729	1.4831893023936e-15	HTLV-I infection: TP53 TBPL2
hsa03320__28	1.33066470743315e-16	DOWN	-8.27208386618125	1.57252766368987e-15	PPAR signaling pathway: ACSL1
hsa04910__48	1.38936262739545e-16	DOWN	-8.26693633421723	1.63163273554754e-15	Insulin signaling pathway: PPARGC1A
hsa04976__36	1.41966162319379e-16	UP	8.26436256823522	1.64663221603773e-15	Bile secretion: SLC10A1
hsa05210__21	1.41966162319379e-16	UP	8.26436256823522	1.64663221603773e-15	Colorectal cancer: BIRC5
hsa03320__44	1.45061189500505e-16	DOWN	-8.26178880225321	1.67220843602116e-15	PPAR signaling pathway: FABP1
hsa05152__51	1.51452171299458e-16	UP	8.25664127028919	1.73523554799805e-15	Tuberculosis: CASP3
hsa04370__25	1.65078299904633e-16	DOWN	-8.24634620636115	1.86856702120967e-15	VEGF signaling pathway: PXN
hsa05200__217	1.65078299904633e-16	UP	8.24634620636115	1.86856702120967e-15	Pathways in cancer: E2F1*
hsa04610__17	1.79911558080897e-16	DOWN	-8.23605114243311	2.0003184475385e-15	Complement and coagulation cascades: PLG
hsa05132__20	1.79911558080897e-16	UP	8.23605114243311	2.0003184475385e-15	Salmonella infection: ACTB
hsa05169__118	1.79911558080897e-16	UP	8.23605114243311	2.0003184475385e-15	Epstein-Barr virus infection: MDM2
hsa05168__29	1.96057173302734e-16	UP	8.22575607850507	2.15433583997566e-15	Herpes simplex infection: IKBKG
hsa05211__41	1.96057173302734e-16	DOWN	-8.22575607850507	2.15433583997566e-15	Renal cell carcinoma: PDGFB*
hsa04110__48	2.04657444286113e-16	UP	8.22060854654105	2.22284010296882e-15	Cell cycle: RB1*
hsa05210__31	2.04657444286113e-16	UP	8.22060854654105	2.22284010296882e-15	Colorectal cancer: BCL2
hsa04923__31	2.22988832560546e-16	UP	8.210313482613	2.40802308265095e-15	Regulation of lipolysis in adipocytes: PRKACA*
hsa05205__319	2.27818984483572e-16	DOWN	-8.20773971663099	2.44612498196933e-15	Proteoglycans in cancer: KDR
hsa04933__30	2.32752241383329e-16	UP	8.20516595064898	2.48489466795042e-15	AGE-RAGE signaling pathway in diabetic complications: CXCL8
hsa05010__47	2.37790770773791e-16	DOWN	-8.20259218466697	2.52434383211273e-15	Alzheimer's disease: C00533
hsa05161__188	2.42936785012691e-16	UP	8.20001841868496	2.56448437662274e-15	Hepatitis B: IFNB1
hsa05200__189	2.53560347177838e-16	UP	8.19487088672094	2.66167537624111e-15	Pathways in cancer: BIRC5
hsa03320__27	2.59042552341018e-16	DOWN	-8.19229712073893	2.70411642138207e-15	PPAR signaling pathway: CPT1C
hsa04071__89	2.64641558743824e-16	DOWN	-8.18972335475692	2.74730104353395e-15	Sphingolipid signaling pathway: C00533
hsa05160__70	2.70359817018174e-16	UP	8.18714958877491	2.79124228668763e-15	Hepatitis C: CDKN1A
hsa04022__37 38	2.76199828394662e-16	DOWN	-8.1845758227929	2.83595342925448e-15	cGMP-PKG signaling pathway: ATP2A1 PLN
hsa04071__65	2.88255374554015e-16	UP	8.17942829082888	2.94365135210323e-15	Sphingolipid signaling pathway: BAX*
hsa04370__23	3.13943419371956e-16	DOWN	-8.16913322690084	3.18864694594543e-15	VEGF signaling pathway: PTK2
hsa04713__60	3.20710208187126e-16	DOWN	-8.16655946091883	3.23986280206241e-15	Circadian entrainment: PER1
hsa03320__26	3.34677927745683e-16	DOWN	-8.16141192895481	3.36288677130555e-15	PPAR signaling pathway: CPT2
hsa04360__117	3.5676087795847e-16	UP	8.15369063100878	3.54684491896277e-15	Axon guidance: CFL1*
hsa05219__21	3.5676087795847e-16	UP	8.15369063100878	3.54684491896277e-15	Bladder cancer: RB1
hsa04910__43	3.80278562052555e-16	DOWN	-8.14596933306275	3.76075483208817e-15	Insulin signaling pathway: G6PC
hsa04620__29	3.96799153780632e-16	UP	8.14082180109873	3.90358958090999e-15	Toll-like receptor signaling pathway: CXCL8
hsa04670__18	4.41237091993224e-16	DOWN	-8.12795297118867	4.31814841591286e-15	Leukocyte transendothelial migration: CDH5
hsa05032__25	4.60386419218226e-16	DOWN	-8.12280543922465	4.45910351397447e-15	Morphine addiction: C00575*
hsa05134__7	4.60386419218226e-16	UP	8.12280543922465	4.45910351397447e-15	Legionellosis: IL18
hsa05142__64	4.8033068811425e-16	UP	8.11765790726063	4.62841724598295e-15	Chagas disease (American trypanosomiasis): CASP8
hsa04750__53	5.3399263547863e-16	UP	8.10478907735058	5.11924572481809e-15	Inflammatory mediator regulation of TRP channels: TRPM8
hsa04933__52	5.81139177542072e-16	DOWN	-8.09449401342254	5.54294677462717e-15	AGE-RAGE signaling pathway in diabetic complications: FOXO1
hsa04620__66	6.1916875971559e-16	UP	8.08677271547651	5.87584898740198e-15	Toll-like receptor signaling pathway: CASP8
hsa04211__56	6.45873462932149e-16	DOWN	-8.08162518351249	6.06798118424754e-15	Longevity regulating pathway - mammal: CAT
hsa04668__48	6.45873462932149e-16	UP	8.08162518351249	6.06798118424754e-15	TNF signaling pathway: CASP3
hsa04932__56	6.59648211018779e-16	UP	8.07905141753048	6.16656213186212e-15	Non-alcoholic fatty liver disease (NAFLD): CASP7
hsa05205__337	6.73712337458927e-16	DOWN	-8.07647765154847	6.26685882220457e-15	Proteoglycans in cancer: CTNNB1**
hsa04151__110	6.88071826358978e-16	UP	8.07390388556646	6.36890128930306e-15	PI3K-Akt signaling pathway: BCL2**
hsa05200__218	7.17701438991348e-16	UP	8.06875635360244	6.61059315619972e-15	Pathways in cancer: CSF3R*
hsa04012__24	7.3298414931083e-16	UP	8.06618258762043	6.71842544661e-15	ErbB signaling pathway: CDKN1A
hsa04925__3	8.49318398065396e-16	DOWN	-8.04816622574635	7.74693820371301e-15	Aldosterone synthesis and secretion: ITPR1
hsa04390__96	8.85775877849952e-16	DOWN	-8.04301869378233	8.00179266576952e-15	Hippo signaling pathway: FGF1
hsa05205__451	8.85775877849952e-16	DOWN	-8.04301869378233	8.00179266576952e-15	Proteoglycans in cancer: KDR**
hsa04115__55	9.23774185539638e-16	UP	8.03787116181831	8.30512772549751e-15	p53 signaling pathway: SHISA5
hsa05130__55	9.43371071152899e-16	UP	8.0352973958363	8.40092058149904e-15	Pathogenic Escherichia coli infection: ACTB
hsa05200__227	9.43371071152899e-16	DOWN	-8.0352973958363	8.40092058149904e-15	Pathways in cancer: FOXO1
hsa04210__72	9.63377392838121e-16	UP	8.03272362985429	8.53861377897561e-15	Apoptosis: BCL2A1
hsa04910__42	9.83801569612829e-16	DOWN	-8.03014986387228	8.67870023146716e-15	Insulin signaling pathway: PCK1
hsa05032__31	1.02593801911919e-15	DOWN	-8.02500233190826	8.92471082372667e-15	Morphine addiction: GABRR3
hsa05032__33	1.02593801911919e-15	DOWN	-8.02500233190826	8.92471082372667e-15	Morphine addiction: GABRR3*
hsa05032__55	1.02593801911919e-15	DOWN	-8.02500233190826	8.92471082372667e-15	Morphine addiction: GABRR3**
hsa04914__39	1.18789879095181e-15	DOWN	-8.00698597003419	1.02859992082878e-14	Progesterone-mediated oocyte maturation: PIK3R5
hsa05215__39	1.21300374685961e-15	UP	8.00441220405218	1.04552020199505e-14	Prostate cancer: RB1
hsa04925__33	1.2386311812489e-15	DOWN	-8.00183843807017	1.06273424181127e-14	Aldosterone synthesis and secretion: CYP11B2
hsa04666__23	1.26479179452439e-15	UP	7.99926467208816	1.08024717359606e-14	Fc gamma R-mediated phagocytosis: RPS6KB1
hsa04115__37	1.29149650257545e-15	UP	7.99669090610615	1.098064220968e-14	p53 signaling pathway: FAS
hsa05134__71	1.31875644103937e-15	UP	7.99411714012414	1.11118535996098e-14	Legionellosis: CXCL8
hsa05168__123	1.31875644103937e-15	UP	7.99411714012414	1.11118535996098e-14	Herpes simplex infection: CYCS
hsa04915__30	1.37498767665509e-15	DOWN	-7.98896960816012	1.1533936805513e-14	Estrogen signaling pathway: CREB3*
hsa04022__19	1.40398238335875e-15	DOWN	-7.98639584217811	1.17248128814715e-14	cGMP-PKG signaling pathway: CNGB1
hsa04919__26	1.43357914869929e-15	DOWN	-7.98382207619609	1.19190054000264e-14	Thyroid hormone signaling pathway: THRB
hsa04115__1	1.49462830752841e-15	UP	7.97867454423207	1.2371835197559e-14	p53 signaling pathway: SIAH1
hsa04919__40	1.59103315206444e-15	DOWN	-7.97095324628604	1.31120670733732e-14	Thyroid hormone signaling pathway: RCAN2
hsa05168__27	1.62450941804142e-15	UP	7.96837948030403	1.33294899410473e-14	Herpes simplex infection: IRF3
hsa04750__62	1.65860098864438e-15	UP	7.96580571432202	1.34920270362382e-14	Inflammatory mediator regulation of TRP channels: TRPM8*
hsa05030__76	1.65867921520544e-15	DOWN	-7.96580571432202	1.34920270362382e-14	Cocaine addiction: PDYN
hsa04064__114	1.76549258510822e-15	UP	7.95808441637599	1.42375990017955e-14	NF-kappa B signaling pathway: BCL2A1*
hsa05132__55	1.76549258510822e-15	UP	7.95808441637599	1.42375990017955e-14	Salmonella infection: IL18
hsa04914__34	1.80258073726296e-15	DOWN	-7.95551065039398	1.44745692534919e-14	Progesterone-mediated oocyte maturation: MAPK14
hsa04022__39	1.91851057823127e-15	DOWN	-7.94778935244795	1.52749210868498e-14	cGMP-PKG signaling pathway: KCNJ8
hsa04727__17 37	1.91851057823127e-15	DOWN	-7.94778935244795	1.52749210868498e-14	GABAergic synapse: GABRA1 GPHN
hsa04750__44	1.95860123005511e-15	UP	7.94521558646594	1.53354746922883e-14	Inflammatory mediator regulation of TRP channels: TRPA1
hsa04750__63	1.95860123005511e-15	UP	7.94521558646594	1.53354746922883e-14	Inflammatory mediator regulation of TRP channels: TRPA1*
hsa04350__27	1.95876206820074e-15	UP	7.94521558646594	1.53354746922883e-14	TGF-beta signaling pathway: ACVR2A*
hsa04915__66	1.95876206820074e-15	DOWN	-7.94521558646594	1.53354746922883e-14	Estrogen signaling pathway: AKT3*
hsa04924__52	1.99984500298551e-15	UP	7.94264182048393	1.55921525336505e-14	Renin secretion: KCNJ2
hsa05216__12	2.17283422878939e-15	DOWN	-7.93234675655589	1.68708905615507e-14	Thyroid cancer: CDH1
hsa05169__117	2.26477317502874e-15	UP	7.92719922459187	1.75123818760453e-14	Epstein-Barr virus infection: CDKN1A
hsa04022__58	2.36054068910372e-15	DOWN	-7.92205169262785	1.81780981755159e-14	cGMP-PKG signaling pathway: MYH7
hsa05222__44	2.40990891174061e-15	UP	7.91947792664584	1.84825258986148e-14	Small cell lung cancer: RB1
hsa04310__57	2.51171521696664e-15	UP	7.91433039468182	1.91850117588631e-14	Wnt signaling pathway: SIAH1
hsa05169__45	2.56419488171512e-15	DOWN	-7.91175662869981	1.95065675414684e-14	Epstein-Barr virus infection: RB1
hsa05030__78	2.78512832482018e-15	DOWN	-7.90146156477176	2.11018392029722e-14	Cocaine addiction: GRIA2
hsa04610__52	2.96303022334604e-15	UP	7.89374026682573	2.23595734524788e-14	Complement and coagulation cascades: CPB2
hsa04022__3	3.08779994875831e-15	DOWN	-7.88859273486171	2.32079044148675e-14	cGMP-PKG signaling pathway: MYL9
hsa05030__37	3.49397947390477e-15	DOWN	-7.87315013896965	2.59493574366287e-14	Cocaine addiction: PRKACA
hsa05145__29	3.49397947390477e-15	UP	7.87315013896965	2.59493574366287e-14	Toxoplasmosis: C06314
hsa05162__93	3.49397947390477e-15	UP	7.87315013896965	2.59493574366287e-14	Measles: TP53
hsa05031__97	3.79353815104183e-15	DOWN	-7.86285507504161	2.80632212039669e-14	Amphetamine addiction: ARC
hsa05100__15	3.95266040542838e-15	DOWN	-7.85770754307759	2.91256819678428e-14	Bacterial invasion of epithelial cells: CTNNA1
hsa04668__38	4.11834962948377e-15	UP	7.85256001111357	3.02280427882812e-14	TNF signaling pathway: CEBPB
hsa05031__10	4.37978227942277e-15	DOWN	-7.84483871316754	3.18977166784317e-14	Amphetamine addiction: CACNA1C
hsa05031__53	4.37978227942277e-15	DOWN	-7.84483871316754	3.18977166784317e-14	Amphetamine addiction: CACNA1C*
hsa04810__21 82	4.47050539473316e-15	UP	7.84226494718553	3.24327399100526e-14	Regulation of actin cytoskeleton: CFL1 ACTB
hsa05110__17	4.95261556122902e-15	DOWN	-7.82939611727547	3.56550369331392e-14	Vibrio cholerae infection: C00698*
hsa05152__98	4.95261556122902e-15	UP	7.82939611727547	3.56550369331392e-14	Tuberculosis: IL23A
hsa04666__27	5.59905443445052e-15	UP	7.81395352138341	4.01550506959257e-14	Fc gamma R-mediated phagocytosis: ARPC5
hsa04668__128	5.95273389168816e-15	UP	7.80623222343738	4.23681325094017e-14	TNF signaling pathway: CHUK*
hsa04919__88	5.95273389168816e-15	DOWN	-7.80623222343738	4.23681325094017e-14	Thyroid hormone signaling pathway: FOXO1
hsa04270__24	6.07544453654851e-15	DOWN	-7.80365845745537	4.30783406949987e-14	Vascular smooth muscle contraction: ACTA2
hsa04370__16	6.45871073331418e-15	DOWN	-7.79593715950934	4.56237498793133e-14	VEGF signaling pathway: HSPB1
hsa04622__11	6.59167962813401e-15	UP	7.79336339352733	4.63886367837596e-14	RIG-I-like receptor signaling pathway: IRF7
hsa04914__29	7.00672667522085e-15	UP	7.7856420955813	4.91255202341044e-14	Progesterone-mediated oocyte maturation: CDK2
hsa04015__30	8.58601383880179e-15	UP	7.75990443576119	5.97522963078095e-14	Rap1 signaling pathway: ITGAL
hsa05169__104	8.58601383880179e-15	UP	7.75990443576119	5.97522963078095e-14	Epstein-Barr virus infection: IRF3
hsa04261__52	8.9414906828022e-15	DOWN	-7.75475690379717	6.19965350294662e-14	Adrenergic signaling in cardiomyocytes: MAPK14
hsa04261__8 38	9.6964467796449e-15	DOWN	-7.74446183986913	6.69839099226205e-14	Adrenergic signaling in cardiomyocytes: ATP2A2 PLN
hsa04919__21 53	9.89478148291588e-15	DOWN	-7.74188807388712	6.81036425142818e-14	Thyroid hormone signaling pathway: THRA C02465
hsa04010__64	1.0097107129092e-14	UP	7.73931430790511	6.92425704217663e-14	MAPK signaling pathway: DDIT3
hsa04010__57	1.07288268172724e-14	UP	7.73159300995908	7.3307147598745e-14	MAPK signaling pathway: NLK
hsa05100__33	1.11714166769295e-14	UP	7.72644547799506	7.60546809273571e-14	Bacterial invasion of epithelial cells: DNM1
hsa04066__52	1.16319609210393e-14	DOWN	-7.72129794603104	7.89041681250283e-14	HIF-1 signaling pathway: FLT1
hsa04072__57	1.18691884968084e-14	UP	7.71872418004903	8.0223759660083e-14	Phospholipase D signaling pathway: C06124
hsa04915__3 11	1.2111175200769e-14	DOWN	-7.71615041406702	8.0985402854964e-14	Estrogen signaling pathway: ESR1 C00951
hsa04915__12 14	1.2111175200769e-14	DOWN	-7.71615041406702	8.0985402854964e-14	Estrogen signaling pathway: ESR1 FOS
hsa04915__12 13	1.2111175200769e-14	DOWN	-7.71615041406702	8.0985402854964e-14	Estrogen signaling pathway: ESR1 C00951*
hsa04115__16	1.33958443623156e-14	UP	7.70328158415697	8.86295477351797e-14	p53 signaling pathway: PPM1D
hsa05214__23	1.33958443623156e-14	DOWN	-7.70328158415697	8.86295477351797e-14	Glioma: MAPK1
hsa05214__56	1.33958443623156e-14	DOWN	-7.70328158415697	8.86295477351797e-14	Glioma: MAPK1*
hsa04151__99	1.54222752263832e-14	UP	7.68526522228289	1.01323269756552e-13	PI3K-Akt signaling pathway: MYB
hsa05012__71	1.54222752263832e-14	DOWN	-7.68526522228289	1.01323269756552e-13	Parkinson's disease: PRKACA*
hsa04668__36	1.57353672774039e-14	UP	7.68269145630088	1.03020052662864e-13	TNF signaling pathway: CREB3
hsa04210__63	1.73970884656955e-14	UP	7.66982262639083	1.13111173795992e-13	Apoptosis: FAS*
hsa04213__60	1.73970884656955e-14	DOWN	-7.66982262639083	1.13111173795992e-13	Longevity regulating pathway - multiple species: CAT
hsa04919__29	1.77495771911569e-14	DOWN	-7.66724886040882	1.15005019110979e-13	Thyroid hormone signaling pathway: HIF1A
hsa04917__68	1.88497389304682e-14	DOWN	-7.65952756246279	1.2171360635859e-13	Prolactin signaling pathway: CCND1
hsa03320__57	1.92311586583303e-14	DOWN	-7.65695379648078	1.23751188763708e-13	PPAR signaling pathway: APOC3
hsa04650__116	1.96201683668278e-14	UP	7.65438003049877	1.25395565854658e-13	Natural killer cell mediated cytotoxicity: FCGR3A
hsa04917__46	1.96201683668278e-14	DOWN	-7.65438003049877	1.25395565854658e-13	Prolactin signaling pathway: GCK
hsa04666__29	2.00169164629896e-14	UP	7.65180626451676	1.27497579776127e-13	Fc gamma R-mediated phagocytosis: WAS
hsa04064__53	2.04215542024943e-14	UP	7.64923249853475	1.29635474143536e-13	NF-kappa B signaling pathway: CXCL8
hsa04920__3	2.25685877443864e-14	DOWN	-7.6363636686247	1.42303276415107e-13	Adipocytokine signaling pathway: C15493
hsa05164__35	2.25685877443864e-14	UP	7.6363636686247	1.42303276415107e-13	Influenza A: IL18
hsa05030__69	2.70068564362446e-14	DOWN	-7.61319977478661	1.69718673055865e-13	Cocaine addiction: PRKACA**
hsa04068__45	2.98326200523305e-14	DOWN	-7.60033094487655	1.86230874014382e-13	FoxO signaling pathway: RBL2
hsa04931__87	2.98326200523305e-14	DOWN	-7.60033094487655	1.86230874014382e-13	Insulin resistance: C00031*
hsa04261__4	3.29486760249437e-14	DOWN	-7.5874621149665	2.05001861757845e-13	Adrenergic signaling in cardiomyocytes: SLC8A1
hsa04917__38	3.36092474136572e-14	DOWN	-7.58488834898449	2.08421702608125e-13	Prolactin signaling pathway: IRF1
hsa04650__39	3.49697021181321e-14	UP	7.57974081702047	2.15436295999903e-13	Natural killer cell mediated cytotoxicity: FAS
hsa04810__35 81 80	3.49697021181321e-14	DOWN	-7.57974081702047	2.15436295999903e-13	Regulation of actin cytoskeleton: MYL12B MYH9 ACTB
hsa04010__131	3.71125174915713e-14	UP	7.57201951907444	2.26410455735917e-13	MAPK signaling pathway: MYC
hsa04115__19	3.71125174915713e-14	UP	7.57201951907444	2.26410455735917e-13	p53 signaling pathway: RFWD2
hsa05162__78	3.71125174915713e-14	UP	7.57201951907444	2.26410455735917e-13	Measles: FAS
hsa05321__83	3.86122622353101e-14	UP	7.56687198711042	2.34797542848374e-13	Inflammatory bowel disease (IBD): IL2
hsa04064__96	3.9384325857708e-14	UP	7.56429822112841	2.38719833182688e-13	NF-kappa B signaling pathway: BCL2A1
hsa04022__60	4.0171565237493e-14	DOWN	-7.5617244551464	2.42708588685689e-13	cGMP-PKG signaling pathway: TRPC6*
hsa04923__66	4.17927487342606e-14	DOWN	-7.55657692318238	2.5169415022973e-13	Regulation of lipolysis in adipocytes: LIPE
hsa04068__13	4.26272955615283e-14	DOWN	-7.55400315720037	2.55899962811859e-13	FoxO signaling pathway: PCK1
hsa03320__21	4.34782237747097e-14	DOWN	-7.55142939121836	2.58530324280632e-13	PPAR signaling pathway: ACAA1
hsa04726__10	4.34782237747097e-14	DOWN	-7.55142939121836	2.58530324280632e-13	Serotonergic synapse: PRKACA
hsa05205__81	4.34782237747097e-14	UP	7.55142939121836	2.58530324280632e-13	Proteoglycans in cancer: CTTN
hsa04370__39	4.43458491779272e-14	DOWN	-7.54885562523635	2.62030976746306e-13	VEGF signaling pathway: RAC1
hsa05031__98	4.43458491779272e-14	DOWN	-7.54885562523635	2.62030976746306e-13	Amphetamine addiction: FOS
hsa04115__54	4.52304935487317e-14	UP	7.54628185925434	2.65587804306459e-13	p53 signaling pathway: PERP
hsa04211__39	4.52304935487317e-14	UP	7.54628185925434	2.65587804306459e-13	Longevity regulating pathway - mammal: TP53*
hsa04621__44	4.61324847488365e-14	UP	7.54370809327233	2.70040307922317e-13	NOD-like receptor signaling pathway: MAPK14
hsa04370__28	4.99206943934918e-14	DOWN	-7.53341302934428	2.91307406103637e-13	VEGF signaling pathway: SHC2
hsa04010__58	5.09145586191705e-14	UP	7.53083926336227	2.96187169180871e-13	MAPK signaling pathway: CDC25B
hsa04010__134	5.61831840969055e-14	UP	7.51797043345222	3.24825239747955e-13	MAPK signaling pathway: ATF4*
hsa04917__33	5.61831840969055e-14	DOWN	-7.51797043345222	3.24825239747955e-13	Prolactin signaling pathway: CSN2
hsa04917__57	5.72994864253737e-14	DOWN	-7.51539666747021	3.30262990776924e-13	Prolactin signaling pathway: ESR1
hsa04015__17	6.07808666339129e-14	UP	7.50767536952418	3.48192830503422e-13	Rap1 signaling pathway: ACTB
hsa04742__31	6.07808666339129e-14	DOWN	-7.50767536952418	3.48192830503422e-13	Taste transduction: C00076*
hsa04360__6	6.32164602544364e-14	DOWN	-7.50252783756016	3.61044768444031e-13	Axon guidance: MAPK1
hsa04310__14	7.99782938885022e-14	UP	7.47164264577604	4.52648235591854e-13	Wnt signaling pathway: PRKCA
hsa04810__8 79	7.99782938885022e-14	DOWN	-7.47164264577604	4.52648235591854e-13	Regulation of actin cytoskeleton: ARPC5 ACTB
hsa04810__8 82	7.99782938885022e-14	DOWN	-7.47164264577604	4.52648235591854e-13	Regulation of actin cytoskeleton: ARPC5 ACTB*
hsa04064__52	8.48093910404551e-14	UP	7.46392134783	4.77116304685674e-13	NF-kappa B signaling pathway: TRAF1
hsa04650__40	8.48093910404551e-14	UP	7.46392134783	4.77116304685674e-13	Natural killer cell mediated cytotoxicity: TNFRSF10D
hsa04068__96	9.16994511505275e-14	DOWN	-7.45362628390196	5.14338115557735e-13	FoxO signaling pathway: CCNG2
hsa05152__24 25	9.53479043386099e-14	UP	7.44847875193794	5.3321045313169e-13	Tuberculosis: ITGB2 ITGAM
hsa04520__7 68	9.72252604226107e-14	DOWN	-7.44590498595593	5.42095739863755e-13	Adherens junction: CDH1 CTNNB1
hsa04610__44	1.03078009860191e-13	UP	7.4381836880099	5.71337995655751e-13	Complement and coagulation cascades: C3
hsa05130__26	1.03078009860191e-13	DOWN	-7.4381836880099	5.71337995655751e-13	Pathogenic Escherichia coli infection: CTNNB1
hsa04742__8	1.05104828680087e-13	UP	7.43560992202789	5.77461909619543e-13	Taste transduction: PLCB2
hsa04917__44	1.05104828680087e-13	DOWN	-7.43560992202789	5.77461909619543e-13	Prolactin signaling pathway: PRLR**
hsa05231__39	1.05104828680087e-13	UP	7.43560992202789	5.77461909619543e-13	Choline metabolism in cancer: EIF4EBP1
hsa04064__36	1.07170802455638e-13	UP	7.43303615604588	5.85389354110885e-13	NF-kappa B signaling pathway: PLCG1
hsa05034__62	1.07170802455638e-13	DOWN	-7.43303615604588	5.85389354110885e-13	Alcoholism: NPY
hsa04360__11	1.09276673649179e-13	DOWN	-7.43046239006387	5.95161941411037e-13	Axon guidance: NFATC2
hsa04012__22	1.13611147413474e-13	UP	7.42531485809985	6.16980768756987e-13	ErbB signaling pathway: EIF4EBP1
hsa03320__30	1.18114470317834e-13	DOWN	-7.42016732613583	6.3775025783681e-13	PPAR signaling pathway: LPL
hsa05034__99	1.18114470317834e-13	DOWN	-7.42016732613583	6.3775025783681e-13	Alcoholism: PDYN
hsa04370__36	1.2279309589808e-13	DOWN	-7.41501979417181	6.59223506264266e-13	VEGF signaling pathway: NOS3
hsa04520__1 13	1.2279309589808e-13	DOWN	-7.41501979417181	6.59223506264266e-13	Adherens junction: SMAD4 SMAD2
hsa04115__15	1.2765371943875e-13	UP	7.40987226220779	6.83365637679234e-13	p53 signaling pathway: TSC2
hsa04310__16	1.30154440998919e-13	UP	7.40729849622578	6.9477328021866e-13	Wnt signaling pathway: CAMK2A
hsa04210__24	1.32703286837854e-13	UP	7.40472473024377	7.06372453168069e-13	Apoptosis: CASP10
hsa04623__8	1.35301165857637e-13	UP	7.40215096426176	7.16143353933801e-13	Cytosolic DNA-sensing pathway: TBK1
hsa04666__50 52	1.35301165857637e-13	UP	7.40215096426176	7.16143353933801e-13	Fc gamma R-mediated phagocytosis: DNM2 AMPH
hsa04725__54	1.40647743498456e-13	DOWN	-7.39700343229774	7.42351432678651e-13	Cholinergic synapse: CHRM1*
hsa05205__120	1.51971194653955e-13	DOWN	-7.38670836836969	7.99870797632443e-13	Proteoglycans in cancer: PLAU
hsa04621__42	1.54939207972675e-13	UP	7.38413460238768	8.1321444631468e-13	NOD-like receptor signaling pathway: MAPK8
hsa04970__12	1.73930146824419e-13	UP	7.36869200649562	9.10347481568475e-13	Salivary secretion: BEST2
hsa05212__29	1.84346335780995e-13	DOWN	-7.36097070854959	9.62185458145803e-13	Pancreatic cancer: VEGFA
hsa04010__79	1.87934396399708e-13	UP	7.35839694256758	9.78195930291003e-13	MAPK signaling pathway: HSPB1
hsa05020__49	1.91591045962088e-13	UP	7.35582317658557	9.94473965090508e-13	Prion diseases: BAX
hsa05217__10	1.99115281376567e-13	DOWN	-7.35067564462155	1.03068213142306e-12	Basal cell carcinoma: PTCH1*
hsa04917__47	2.06929619986593e-13	DOWN	-7.34552811265753	1.06818888998574e-12	Prolactin signaling pathway: INS
hsa04750__39	2.19219179287714e-13	DOWN	-7.3378068147115	1.12544491224485e-12	Inflammatory mediator regulation of TRP channels: C01245*
hsa05211__45	2.19219179287714e-13	DOWN	-7.3378068147115	1.12544491224485e-12	Renal cell carcinoma: ETS1
hsa04740__21	2.23472893729628e-13	DOWN	-7.33523304872949	1.14415685917703e-12	Olfactory transduction: PDE1A
hsa04722__46	2.55605261993004e-13	DOWN	-7.31721668685542	1.30511491110015e-12	Neurotrophin signaling pathway: ATF4*
hsa04151__51	2.65591588516277e-13	DOWN	-7.31206915489139	1.34877458060023e-12	PI3K-Akt signaling pathway: NOS3
hsa05220__6	2.65591588516277e-13	UP	7.31206915489139	1.34877458060023e-12	Chronic myeloid leukemia: TP53
hsa04020__8	2.81293627573294e-13	DOWN	-7.30434785694536	1.42083528551134e-12	Calcium signaling pathway: PDE1A
hsa05205__236	2.81293627573294e-13	DOWN	-7.30434785694536	1.42083528551134e-12	Proteoglycans in cancer: ITGAV
hsa04151__33	2.86727553906378e-13	UP	7.30177409096335	1.44439966163561e-12	PI3K-Akt signaling pathway: TP53
hsa05010__51	2.92264547548036e-13	DOWN	-7.29920032498134	1.46835584182556e-12	Alzheimer's disease: ATF6
hsa04064__2	2.97906526040273e-13	UP	7.29662655899933	1.48874032561083e-12	NF-kappa B signaling pathway: BCL2L1
hsa05162__81	2.97906526040273e-13	UP	7.29662655899933	1.48874032561083e-12	Measles: TNFRSF10D
hsa04919__103	3.0365544187881e-13	DOWN	-7.29405279301732	1.51344449679121e-12	Thyroid hormone signaling pathway: CCND1
hsa04621__43	3.09513283136534e-13	UP	7.29147902703531	1.53855941537976e-12	NOD-like receptor signaling pathway: MAPK1
hsa05145__4 5	3.60548150246485e-13	UP	7.27088889917923	1.7828157218767e-12	Toxoplasmosis: MAP3K7 TAB1
hsa05164__78	3.60548150246485e-13	UP	7.27088889917923	1.7828157218767e-12	Influenza A: GSK3B
hsa05152__129	3.89078643694695e-13	UP	7.26059383525119	1.91884191995363e-12	Tuberculosis: IFNB1
hsa04621__34 35	4.04163870366961e-13	UP	7.25544630328717	1.98283005853661e-12	NOD-like receptor signaling pathway: CASP1 PYCARD
hsa05200__214	4.04163870366961e-13	UP	7.25544630328717	1.98283005853661e-12	Pathways in cancer: CSF3R
hsa04540__21	4.79461473401212e-13	DOWN	-7.23228240944907	2.34611486593979e-12	Gap junction: C03758
hsa05164__24	5.1720464978462e-13	UP	7.22198734552103	2.52422736868909e-12	Influenza A: IRF7
hsa04918__10	5.47407934529571e-13	DOWN	-7.214266047575	2.66471375383695e-12	Thyroid hormone synthesis: TG
hsa04024__110	5.57855419209271e-13	DOWN	-7.21169228159299	2.70157302240778e-12	cAMP signaling pathway: FOS
hsa04340__17	5.57855419209271e-13	UP	7.21169228159299	2.70157302240778e-12	Hedgehog signaling pathway: SMO
hsa04922__24	5.67689524467956e-13	DOWN	-7.20911851561098	2.74213011947375e-12	Glucagon signaling pathway: PFKL
hsa04915__21	5.7934106263035e-13	DOWN	-7.20654474962897	2.78409682015966e-12	Estrogen signaling pathway: CREB3
hsa05145__35	5.7934106263035e-13	UP	7.20654474962897	2.78409682015966e-12	Toxoplasmosis: CASP3
hsa05169__60	6.73708233025416e-13	UP	7.18595462177289	3.22933104554785e-12	Epstein-Barr virus infection: NFKB1
hsa04310__13	6.8651704870674e-13	UP	7.18338085579088	3.28235504966912e-12	Wnt signaling pathway: NFATC1
hsa04014__44	7.68544111992991e-13	DOWN	-7.16793825989881	3.6652141787686e-12	Ras signaling pathway: ETS1
hsa04750__51	7.83105313525986e-13	DOWN	-7.1653644939168	3.71579516190739e-12	Inflammatory mediator regulation of TRP channels: TRPV4
hsa04750__61	7.83105313525986e-13	DOWN	-7.1653644939168	3.71579516190739e-12	Inflammatory mediator regulation of TRP channels: TRPV4*
hsa05034__61	8.13091418650878e-13	DOWN	-7.16021696195278	3.84835963638539e-12	Alcoholism: CRH
hsa04115__20	8.60170447428254e-13	UP	7.15249566400675	4.06095545406455e-12	p53 signaling pathway: RRM2B
hsa04010__63	9.09922115510864e-13	UP	7.14477436606072	4.28507181715517e-12	MAPK signaling pathway: MAX
hsa04010__61	9.44647743350802e-13	UP	7.1396268340967	4.426416732559e-12	MAPK signaling pathway: ATF4
hsa04022__43	9.44647743350802e-13	DOWN	-7.1396268340967	4.426416732559e-12	cGMP-PKG signaling pathway: MAPK1
hsa04015__82	1.05681526305164e-12	UP	7.12418423820464	4.92743394360801e-12	Rap1 signaling pathway: ITGA2B
hsa04620__76	1.05681526305164e-12	UP	7.12418423820464	4.92743394360801e-12	Toll-like receptor signaling pathway: CCL3L3
hsa04360__40 139	1.07673967708668e-12	DOWN	-7.12161047222263	5.00790557734127e-12	Axon guidance: UNC5D DCC
hsa05164__70	1.1177006891269e-12	UP	7.11646294025861	5.17280688391488e-12	Influenza A: RNASEL
hsa05168__83	1.1177006891269e-12	UP	7.11646294025861	5.17280688391488e-12	Herpes simplex infection: RNASEL
hsa04261__66	1.18202463421492e-12	DOWN	-7.10874164231258	5.45706213191605e-12	Adrenergic signaling in cardiomyocytes: C01245
hsa05200__226	1.20426263718434e-12	UP	7.10616787633057	5.5461017040916e-12	Pathways in cancer: CDKN1A*
hsa04210__57	1.2973934298766e-12	UP	7.09587281240253	5.9603967108512e-12	Apoptosis: BAK1
hsa04668__47	1.39758093172401e-12	UP	7.08557774847448	6.40501114807175e-12	TNF signaling pathway: CASP7
hsa04390__13	1.47766590702725e-12	UP	7.07785645052845	6.73916077501022e-12	Hippo signaling pathway: BIRC5
hsa04970__32	1.47766590702725e-12	DOWN	-7.07785645052845	6.73916077501022e-12	Salivary secretion: RYR3
hsa04015__67	1.53353956173783e-12	UP	7.07270891856443	6.9770480302794e-12	Rap1 signaling pathway: AKT3
hsa05200__219	1.56224848344188e-12	UP	7.07013515258242	7.09049492847171e-12	Pathways in cancer: MYC**
hsa04068__44	1.59148450273102e-12	DOWN	-7.06756138660041	7.2057816400761e-12	FoxO signaling pathway: CDKN1B
hsa04976__59	1.62125709992734e-12	UP	7.0649876206184	7.32293771818142e-12	Bile secretion: ABCB4
hsa05131__12	1.74590877352919e-12	UP	7.05469255669036	7.86705655985936e-12	Shigellosis: ARPC5
hsa05231__50	1.91500562644461e-12	UP	7.04182372678031	8.60836261265412e-12	Choline metabolism in cancer: WASF2
hsa05214__27	1.98705405937177e-12	DOWN	-7.03667619481629	8.88970137514181e-12	Glioma: MTOR
hsa05214__48	1.98705405937177e-12	DOWN	-7.03667619481629	8.88970137514181e-12	Glioma: MTOR*
hsa04066__43	2.0240687487167e-12	DOWN	-7.03410242883428	9.03378902336977e-12	HIF-1 signaling pathway: PFKL
hsa04610__11	2.17901048280167e-12	UP	7.02380736490624	9.67933970965564e-12	Complement and coagulation cascades: F2R
hsa05221__35	2.17901048280167e-12	UP	7.02380736490624	9.67933970965564e-12	Acute myeloid leukemia: EIF4EBP1
hsa04919__84	2.30279461746654e-12	UP	7.0160860669602	1.02050733165557e-11	Thyroid hormone signaling pathway: TP53*
hsa04210__61	2.43346817481469e-12	UP	7.00836476901417	1.0758792236416e-11	Apoptosis: APAF1
hsa05321__75	2.47862129723424e-12	UP	7.00579100303216	1.09326981631529e-11	Inflammatory bowel disease (IBD): IL10
hsa04152__35	2.61906784767259e-12	DOWN	-6.99806970508613	1.15251252594305e-11	AMPK signaling pathway: PFKFB1
hsa04924__49	2.76731057337677e-12	DOWN	-6.9903484071401	1.21490106714368e-11	Renin secretion: PDE1A
hsa04668__20	2.87067845799395e-12	UP	6.98520087517608	1.25150923957555e-11	TNF signaling pathway: IKBKG
hsa04670__39	2.87067845799395e-12	UP	6.98520087517608	1.25150923957555e-11	Leukocyte transendothelial migration: MAPK14
hsa04920__10	2.87067845799395e-12	DOWN	-6.98520087517608	1.25150923957555e-11	Adipocytokine signaling pathway: PCK1
hsa04620__87	3.08890076848873e-12	UP	6.97490581124804	1.334263113561e-11	Toll-like receptor signaling pathway: CCL4L1
hsa05014__5	3.08890076848873e-12	UP	6.97490581124804	1.334263113561e-11	Amyotrophic lateral sclerosis (ALS): TOMM40
hsa05152__20	3.08890076848873e-12	UP	6.97490581124804	1.334263113561e-11	Tuberculosis: FCGR1A
hsa05211__3	3.08890076848873e-12	DOWN	-6.97490581124804	1.334263113561e-11	Renal cell carcinoma: VEGFA
hsa04630__35	3.3233660525887e-12	DOWN	-6.96461074732	1.43224881027848e-11	Jak-STAT signaling pathway: MTOR
hsa04722__73 77	3.51058259842879e-12	DOWN	-6.95688944937397	1.50947018362648e-11	Neurotrophin signaling pathway: NGFRAP1 YWHAE
hsa05014__13	3.57525662731416e-12	UP	6.95431568339196	1.53376876774505e-11	Amyotrophic lateral sclerosis (ALS): CASP3
hsa04064__3	3.64109844553777e-12	UP	6.95174191740995	1.54787872831798e-11	NF-kappa B signaling pathway: BCL2
hsa04913__21	3.64109844553777e-12	DOWN	-6.95174191740995	1.54787872831798e-11	Ovarian steroidogenesis: CYP17A1
hsa04913__22	3.64109844553777e-12	DOWN	-6.95174191740995	1.54787872831798e-11	Ovarian steroidogenesis: CYP17A1*
hsa04924__23	3.64109844553777e-12	DOWN	-6.95174191740995	1.54787872831798e-11	Renin secretion: ITPR1
hsa04211__29	3.70812869530945e-12	DOWN	-6.94916815142794	1.569273382542e-11	Longevity regulating pathway - mammal: EIF4E
hsa04919__30	3.70812869530945e-12	DOWN	-6.94916815142794	1.569273382542e-11	Thyroid hormone signaling pathway: MYH6
hsa04520__58	3.77038620549904e-12	DOWN	-6.94659438544593	1.59203498429948e-11	Adherens junction: CDH1*
hsa04151__36	3.84583884785569e-12	DOWN	-6.94402061946391	1.62025363119302e-11	PI3K-Akt signaling pathway: PCK1
hsa04010__78	3.98855946562875e-12	DOWN	-6.93887308749989	1.66544516353698e-11	MAPK signaling pathway: MAP3K4
hsa04510__24 69	3.98855946562875e-12	UP	6.93887308749989	1.66544516353698e-11	Focal adhesion: ZYX ACTB
hsa05200__213	3.98855946562875e-12	UP	6.93887308749989	1.66544516353698e-11	Pathways in cancer: CSF2RA
hsa05222__36	3.98855946562875e-12	DOWN	-6.93887308749989	1.66544516353698e-11	Small cell lung cancer: PTGS2
hsa04210__75	4.21242691683419e-12	UP	6.93115178955386	1.75502221213557e-11	Apoptosis: BAK1*
hsa04970__39	4.36827216097371e-12	UP	6.92600425758984	1.81199799238663e-11	Salivary secretion: KCNN4
hsa04115__34	4.36846775173572e-12	UP	6.92600425758984	1.81199799238663e-11	p53 signaling pathway: ZMAT3
hsa05211__48	4.61320858556981e-12	DOWN	-6.91828295964381	1.909299324292e-11	Renal cell carcinoma: JUN
hsa04010__54	4.78378457215493e-12	DOWN	-6.91313542767979	1.96689960855123e-11	MAPK signaling pathway: NR4A1
hsa04210__3	4.78378457215493e-12	UP	6.91313542767979	1.96689960855123e-11	Apoptosis: BCL2L1
hsa04621__33 35	4.78378457215493e-12	UP	6.91313542767979	1.96689960855123e-11	NOD-like receptor signaling pathway: NLRC4 PYCARD
hsa04666__51	5.3334647175983e-12	UP	6.89769283178773	2.18811794855179e-11	Fc gamma R-mediated phagocytosis: NCF1
hsa04916__4	5.53009739674922e-12	UP	6.89254529982371	2.26384597134897e-11	Melanogenesis: TYR
hsa04728__74	6.27589401144422e-12	DOWN	-6.87452893794964	2.56356627119646e-11	Dopaminergic synapse: GRIN2A
hsa04330__11	6.39018283309925e-12	UP	6.87195517196763	2.60458862112657e-11	Notch signaling pathway: PTCRA
hsa04390__5	6.50651065431105e-12	DOWN	-6.86938140598561	2.64054719642559e-11	Hippo signaling pathway: SAV1
hsa04530__1 5	6.50651065431105e-12	DOWN	-6.86938140598561	2.64054719642559e-11	Tight junction: IGSF5 IGSF5
hsa04726__45	6.6247380673929e-12	UP	6.8668076400036	2.68273336823949e-11	Serotonergic synapse: TRPC1
hsa04390__60	6.86808709028232e-12	DOWN	-6.86166010803958	2.77529798766462e-11	Hippo signaling pathway: CTGF*
hsa04010__87	6.99293296044903e-12	UP	6.85908634205757	2.81968262503943e-11	MAPK signaling pathway: STK3
hsa04066__55	7.24933284127406e-12	DOWN	-6.85393881009355	2.9168086528381e-11	HIF-1 signaling pathway: ANGPT1
hsa04152__82	7.38096497267397e-12	DOWN	-6.85136504411154	2.96342589394324e-11	AMPK signaling pathway: HMGCR
hsa04022__48	7.6512939290303e-12	DOWN	-6.84621751214752	3.06541178947717e-11	cGMP-PKG signaling pathway: SLC8A2
hsa04933__63	7.79007292921101e-12	DOWN	-6.84364374616551	3.11437170935904e-11	AGE-RAGE signaling pathway in diabetic complications: SELE
hsa04150__33	8.22137585494447e-12	UP	6.83592244821948	3.27982276676022e-11	mTOR signaling pathway: RPS6
hsa05100__24	8.52182044588252e-12	DOWN	-6.83077491625546	3.39247894445196e-11	Bacterial invasion of epithelial cells: ACTB
hsa04520__34	8.99276053735318e-12	DOWN	-6.82305361830943	3.57238838259759e-11	Adherens junction: RHOA
hsa04622__21 22 23	9.15533559818796e-12	UP	6.82047985232742	3.62929864746734e-11	RIG-I-like receptor signaling pathway: CHUK IKBKB IKBKG
hsa04064__142	9.3207892002033e-12	UP	6.81790608634541	3.68710798045937e-11	NF-kappa B signaling pathway: NFKB2*
hsa04930__15	9.83492400133324e-12	DOWN	-6.81018478839938	3.87417656153148e-11	Type II diabetes mellitus: C00031*
hsa05215__24	9.83492400133324e-12	UP	6.81018478839938	3.87417656153148e-11	Prostate cancer: CDKN1A
hsa04062__38	1.03768116871941e-11	UP	6.80246349045335	4.0790855983761e-11	Chemokine signaling pathway: NCF1
hsa04370__14	1.05638591330938e-11	DOWN	-6.79988972447134	4.14394390628043e-11	VEGF signaling pathway: PTGS2
hsa04068__47	1.13456413277443e-11	DOWN	-6.78959466054329	4.43211227751176e-11	FoxO signaling pathway: GADD45G
hsa04068__54	1.13456413277443e-11	DOWN	-6.78959466054329	4.43211227751176e-11	FoxO signaling pathway: GADD45G*
hsa04723__73	1.21840130825621e-11	UP	6.77929959661525	4.73990902321619e-11	Retrograde endocannabinoid signaling: MAPK14*
hsa04723__68	1.21840130825621e-11	UP	6.77929959661525	4.73990902321619e-11	Retrograde endocannabinoid signaling: MAPK14
hsa04919__46	1.28523254296827e-11	DOWN	-6.77157829866922	4.98957014098633e-11	Thyroid hormone signaling pathway: ATP1B4
hsa04742__4	1.30829753676617e-11	DOWN	-6.76900453268721	5.06864138470854e-11	Taste transduction: TRPM5
hsa04068__14	1.33176780784853e-11	DOWN	-6.7664307667052	5.14895413775182e-11	FoxO signaling pathway: G6PC
hsa04064__136	1.45544615418348e-11	UP	6.75356193679515	5.61557150659295e-11	NF-kappa B signaling pathway: TNFSF13B*
hsa04921__65	1.56242605119823e-11	UP	6.74326687286711	6.01598063565875e-11	Oxytocin signaling pathway: TRPM2
hsa04210__31 32 33	1.67709501944758e-11	UP	6.73297180893907	6.44429763096525e-11	Apoptosis: TRAF2 RIPK1 TRADD
hsa04110__60 10 11 12 13 14 9	1.70702612256357e-11	DOWN	-6.73039804295706	6.54592262101417e-11	Cell cycle: CDC6 ORC3 ORC5 ORC4 ORC2 ORC1 ORC6
hsa05012__57	1.73748012186709e-11	UP	6.72782427697505	6.64913472299035e-11	Parkinson's disease: CASP3
hsa04152__62	1.79999267680799e-11	UP	6.72267674501103	6.87436227585814e-11	AMPK signaling pathway: EIF4EBP1
hsa04360__89	1.83206954083462e-11	UP	6.72010297902901	6.98267478139604e-11	Axon guidance: CAMK2A
hsa04350__41	1.86470592269875e-11	DOWN	-6.717529213047	7.09267698127721e-11	TGF-beta signaling pathway: SMAD4***
hsa04724__3	1.96606836881536e-11	DOWN	-6.70980791510097	7.46311609091728e-11	Glutamatergic synapse: GRIK1
hsa04360__18	2.00103981952325e-11	DOWN	-6.70723414911896	7.58055205823425e-11	Axon guidance: PTK2
hsa05168__92 93	2.03662009995721e-11	UP	6.70466038313695	7.69981723907362e-11	Herpes simplex infection: IRF9 STAT1
hsa04520__9 57	2.07281956964255e-11	DOWN	-6.70208661715494	7.78965594271671e-11	Adherens junction: LEF1 CTNNB1
hsa04520__44 49	2.07281956964255e-11	DOWN	-6.70208661715494	7.78965594271671e-11	Adherens junction: ACTB VCL
hsa04530__11 62	2.07281956964255e-11	DOWN	-6.70208661715494	7.78965594271671e-11	Tight junction: TJP1 SHROOM1
hsa04066__5	2.18523930631309e-11	DOWN	-6.69436531920891	8.19573783744971e-11	HIF-1 signaling pathway: VEGFA
hsa04961__12	2.47127541278284e-11	DOWN	-6.67634895733484	9.23166302309933e-11	Endocrine and other factor-regulated calcium reabsorption: SLC8A1
hsa05142__84	2.47127541278284e-11	UP	6.67634895733484	9.23166302309933e-11	Chagas disease (American trypanosomiasis): NFKB1*
hsa04064__131	2.65085549707093e-11	UP	6.6660538934068	9.88285214086563e-11	NF-kappa B signaling pathway: CCL4L1
hsa04921__60	2.7453744642264e-11	UP	6.66090636144278	1.02149675609533e-10	Oxytocin signaling pathway: ELK1
hsa04210__73	3.10289553157295e-11	UP	6.6428899995687	1.15224124581533e-10	Apoptosis: TRAF1
hsa04064__132	3.15755524362903e-11	UP	6.64031623358669	1.16792250054704e-10	NF-kappa B signaling pathway: VCAM1
hsa05231__59	3.15755524362903e-11	DOWN	-6.64031623358669	1.16792250054704e-10	Choline metabolism in cancer: PLA2G4B
hsa04010__13	3.26971656416913e-11	UP	6.63516870162267	1.20703289274534e-10	MAPK signaling pathway: STMN1
hsa04976__41	3.32725015324925e-11	UP	6.63259493564066	1.22586334077556e-10	Bile secretion: CYP7A1
hsa03320__25	3.44530511877004e-11	DOWN	-6.62744740367664	1.26687442625614e-10	PPAR signaling pathway: EHHADH
hsa05164__31 32 33	3.62999197584129e-11	UP	6.61972610573061	1.32962544000958e-10	Influenza A: NLRP3 PYCARD CASP1
hsa04623__17	3.63011096713633e-11	UP	6.61972610573061	1.32962544000958e-10	Cytosolic DNA-sensing pathway: NFKB1
hsa04922__70	3.75866783886851e-11	DOWN	-6.61457857376659	1.3740344103568e-10	Glucagon signaling pathway: PFKFB1
hsa05212__31	3.89167639303534e-11	UP	6.60943104180257	1.41989513446862e-10	Pancreatic cancer: RAC1*
hsa04015__63	3.95989689259412e-11	UP	6.60685727582056	1.43919656889446e-10	Rap1 signaling pathway: GNAI1
hsa05211__27	3.95989689259412e-11	DOWN	-6.60685727582056	1.43919656889446e-10	Renal cell carcinoma: VEGFA*
hsa04621__21 31 41	4.02928713669454e-11	UP	6.60428350983855	1.45877274178209e-10	NOD-like receptor signaling pathway: NLRP3 CARD8 CASP1
hsa04630__34	4.02928713669454e-11	DOWN	-6.60428350983855	1.45877274178209e-10	Jak-STAT signaling pathway: AOX1
hsa04066__63	4.24467383582035e-11	UP	6.59656221189252	1.53085261756362e-10	HIF-1 signaling pathway: TIMP1*
hsa04066__57	4.24467383582035e-11	UP	6.59656221189252	1.53085261756362e-10	HIF-1 signaling pathway: TIMP1
hsa04620__40	4.62893910449571e-11	UP	6.58369338198247	1.66624072362978e-10	Toll-like receptor signaling pathway: CCL5
hsa04931__13	4.70977804913501e-11	DOWN	-6.58111961600046	1.69209807922078e-10	Insulin resistance: AKT2
hsa04520__4	4.79199765418031e-11	DOWN	-6.57854585001845	1.71835183057344e-10	Adherens junction: CTNND1
hsa04622__45	5.04717257509376e-11	UP	6.57082455207241	1.80640709878117e-10	RIG-I-like receptor signaling pathway: MAPK14
hsa05142__7	5.21536296650694e-11	UP	6.56567702010839	1.86305456541189e-10	Chagas disease (American trypanosomiasis): C1QA
hsa04015__11	5.31562517992996e-11	UP	6.56310325412638	1.89526749773973e-10	Rap1 signaling pathway: RAC1
hsa04360__145	5.7943979412367e-11	DOWN	-6.55023442421633	2.05816138593266e-10	Axon guidance: ABLIM3
hsa05200__76	5.7943979412367e-11	UP	6.55023442421633	2.05816138593266e-10	Pathways in cancer: RAC1
hsa04971__55	6.20755781535668e-11	DOWN	-6.53993936028829	2.20075493114249e-10	Gastric acid secretion: MYLK4
hsa04933__28	6.88184569192733e-11	UP	6.52449676439623	2.43521432300027e-10	AGE-RAGE signaling pathway in diabetic complications: VCAM1
hsa05169__64	7.12213897809269e-11	UP	6.51934923243221	2.51550735711206e-10	Epstein-Barr virus infection: NFKB2
hsa05140__43	7.37063132879188e-11	UP	6.51420170046819	2.59838954348967e-10	Leishmaniasis: MAPK14
hsa04670__15	7.49791811811797e-11	DOWN	-6.51162793448618	2.62850965049651e-10	Leukocyte transendothelial migration: PECAM1
hsa04010__15	7.49803710838814e-11	UP	6.51162793448618	2.62850965049651e-10	MAPK signaling pathway: NFKB1
hsa05145__13	7.49803710838814e-11	UP	6.51162793448618	2.62850965049651e-10	Toxoplasmosis: GNAI1
hsa04114__59	7.62759569601484e-11	UP	6.50905416850417	2.66894828916423e-10	Oocyte meiosis: REC8*
hsa04530__5 10	7.75934259548996e-11	DOWN	-6.50648040252216	2.71000088046945e-10	Tight junction: IGSF5 MAGI1
hsa04022__71	8.02954620637431e-11	UP	6.50133287055814	2.79398468921802e-10	cGMP-PKG signaling pathway: PPIF
hsa04390__12	8.02954620637431e-11	DOWN	-6.50133287055814	2.79398468921802e-10	Hippo signaling pathway: CTGF
hsa04064__4	8.30894354174075e-11	UP	6.49618533859412	2.88053596216437e-10	NF-kappa B signaling pathway: BIRC2
hsa04152__63	8.30894354174075e-11	UP	6.49618533859412	2.88053596216437e-10	AMPK signaling pathway: PPARG
hsa05152__81	8.7459480108988e-11	UP	6.48846404064808	3.02645235957253e-10	Tuberculosis: IFNA1
hsa05160__12 13 14	8.89654990112814e-11	UP	6.48589027466607	3.07290758533452e-10	Hepatitis C: IKBKG CHUK IKBKB
hsa04666__38	9.20539914979495e-11	DOWN	-6.48074274270205	3.17375137659903e-10	Fc gamma R-mediated phagocytosis: CFL1
hsa03320__42	9.36373042570307e-11	DOWN	-6.47816897672004	3.21653555208338e-10	PPAR signaling pathway: ACOX1
hsa05214__52	9.36373042570307e-11	UP	6.47816897672004	3.21653555208338e-10	Glioma: E2F1*
hsa04115__22	1.0024110567857e-10	UP	6.467873912792	3.43709922573053e-10	p53 signaling pathway: STEAP3
hsa04922__78	1.0196192915282e-10	DOWN	-6.46530014680999	3.48973524368213e-10	Glucagon signaling pathway: ACACA
hsa04932__58	1.05490654277804e-10	UP	6.46015261484597	3.60394435250896e-10	Non-alcoholic fatty liver disease (NAFLD): BAX
hsa04713__56	1.07299508488992e-10	DOWN	-6.45757884886396	3.65908850182971e-10	Circadian entrainment: KCNJ3
hsa04151__2	1.11008638799641e-10	DOWN	-6.45243131689994	3.77871797653126e-10	PI3K-Akt signaling pathway: EIF4E
hsa04923__16	1.12909913708684e-10	DOWN	-6.44985755091793	3.8364869413855e-10	Regulation of lipolysis in adipocytes: PLIN1
hsa04933__62	1.14843007593563e-10	UP	6.44728378493592	3.89512655718963e-10	AGE-RAGE signaling pathway in diabetic complications: AGER**
hsa04115__36	1.16808439944327e-10	UP	6.44471001895391	3.94753702617608e-10	p53 signaling pathway: EI24
hsa04151__27	1.16808439944327e-10	UP	6.44471001895391	3.94753702617608e-10	PI3K-Akt signaling pathway: FASLG
hsa05016__60	1.27139446126856e-10	UP	6.43184118904386	4.28127274681654e-10	Huntington's disease: CASP3*
hsa05134__35	1.27139446126856e-10	UP	6.43184118904386	4.28127274681654e-10	Legionellosis: CASP3
hsa05321__46	1.31517347432208e-10	UP	6.42669365707984	4.42077094499317e-10	Inflammatory bowel disease (IBD): IFNG*
hsa04340__14	1.36042468668068e-10	DOWN	-6.42154612511581	4.56471068977321e-10	Hedgehog signaling pathway: PTCH1
hsa04912__26	1.3836173916699e-10	UP	6.4189723591338	4.6342550426876e-10	GnRH signaling pathway: PLD1
hsa04068__49	1.4311678843811e-10	DOWN	-6.41382482716978	4.78499013301082e-10	FoxO signaling pathway: BCL2L11
hsa05162__62	1.48031414791687e-10	DOWN	-6.40867729520576	4.94051560201741e-10	Measles: IL12A
hsa05223__24	1.63785799754453e-10	UP	6.3932346993137	5.45662265494001e-10	Non-small cell lung cancer: STK4
hsa05014__51	1.66566164401964e-10	UP	6.39066093333169	5.53943049400513e-10	Amyotrophic lateral sclerosis (ALS): DERL1
hsa04152__64	1.72265940246456e-10	DOWN	-6.38551340136767	5.71886398804046e-10	AMPK signaling pathway: ACACB
hsa04621__23	1.87362098458314e-10	UP	6.37264457145762	6.20905437395366e-10	NOD-like receptor signaling pathway: CASP1
hsa05160__66	1.93755914023997e-10	UP	6.3674970394936	6.39837192356927e-10	Hepatitis C: GSK3B
hsa05162__101	1.93755914023997e-10	DOWN	-6.3674970394936	6.39837192356927e-10	Measles: CDKN1B
hsa04068__67	2.00362727115811e-10	DOWN	-6.36234950752958	6.60493972369488e-10	FoxO signaling pathway: GABARAP
hsa05166__114 112 113	2.0374816012979e-10	DOWN	-6.35977574154757	6.70477745856175e-10	HTLV-I infection: DLG1 CTNNB1 APC2
hsa05140__26	2.17857540688551e-10	DOWN	-6.34948067761952	7.15654403765363e-10	Leishmaniasis: C00533
hsa05215__14	2.44879439338701e-10	DOWN	-6.33146431574545	8.03016520972807e-10	Prostate cancer: CCND1
hsa04010__65	2.61762480932527e-10	UP	6.32116925181741	8.53909204292047e-10	MAPK signaling pathway: ELK4
hsa04520__17	2.61762480932527e-10	DOWN	-6.32116925181741	8.53909204292047e-10	Adherens junction: SNAI1
hsa04662__24	2.61762480932527e-10	DOWN	-6.32116925181741	8.53909204292047e-10	B cell receptor signaling pathway: FOS
hsa04071__57	2.8447095537654e-10	UP	6.30830042190736	9.24776687115083e-10	Sphingolipid signaling pathway: BAX
hsa04211__52	2.8447095537654e-10	UP	6.30830042190736	9.24776687115083e-10	Longevity regulating pathway - mammal: PPARG
hsa04022__44	2.94083358008005e-10	DOWN	-6.30315288994334	9.54374144554474e-10	cGMP-PKG signaling pathway: BAD
hsa04630__33	3.04012689864948e-10	DOWN	-6.29800535797932	9.84896283200409e-10	Jak-STAT signaling pathway: RAF1
hsa04920__31	3.09099372474701e-10	DOWN	-6.29543159199731	9.99651843166889e-10	Adipocytokine signaling pathway: AGRP
hsa04972__39	3.14269128609214e-10	DOWN	-6.2928578260153	1.01462490147202e-09	Pancreatic secretion: KCNMA1*
hsa04015__14	3.19523280184744e-10	UP	6.29028406003329	1.02981859942905e-09	Rap1 signaling pathway: MAPK14
hsa05030__73	3.41411001547893e-10	DOWN	-6.27998899610525	1.09847820532276e-09	Cocaine addiction: NFKB1
hsa05200__65	3.47107685757812e-10	UP	6.27741523012324	1.11489801972467e-09	Pathways in cancer: STK4
hsa04064__25	3.58780827910155e-10	UP	6.27226769815921	1.15042521440816e-09	NF-kappa B signaling pathway: NFKB2
hsa05205__400	3.77012393311505e-10	DOWN	-6.26454640021318	1.20682502049799e-09	Proteoglycans in cancer: ITGA2*
hsa05210__53	3.8328821601364e-10	DOWN	-6.26197263423117	1.22482747940413e-09	Colorectal cancer: CCND1*
hsa04066__51	3.89665983519763e-10	DOWN	-6.25939886824916	1.24309402891958e-09	HIF-1 signaling pathway: TFRC
hsa05031__101	3.96147308892613e-10	DOWN	-6.25682510226715	1.26162846340546e-09	Amphetamine addiction: FOS*
hsa04068__58	4.0273383000363e-10	DOWN	-6.25425133628514	1.27827173408247e-09	FoxO signaling pathway: KLF2
hsa04914__11	4.0273383000363e-10	UP	6.25425133628514	1.27827173408247e-09	Progesterone-mediated oocyte maturation: CDK1
hsa04727__47	4.23141326416428e-10	DOWN	-6.24653003833911	1.34078002080349e-09	GABAergic synapse: CACNA1A*
hsa04024__24	4.44557008218382e-10	DOWN	-6.23880874039308	1.40626703441472e-09	cAMP signaling pathway: PLN
hsa05200__80	4.51927922871818e-10	UP	6.23623497441107	1.42718078500192e-09	Pathways in cancer: TP53
hsa04024__108	4.67029342689287e-10	UP	6.23108744244705	1.47239619951874e-09	cAMP signaling pathway: AMH
hsa04064__113	4.98724156525245e-10	UP	6.22079237851901	1.56444522556083e-09	NF-kappa B signaling pathway: CFLAR
hsa04610__58	4.98724156525245e-10	UP	6.22079237851901	1.56444522556083e-09	Complement and coagulation cascades: F2RL2
hsa05120__18	4.98724156525245e-10	UP	6.22079237851901	1.56444522556083e-09	Epithelial cell signaling in Helicobacter pylori infection: CCL5
hsa04650__14	5.06970201701994e-10	UP	6.218218612537	1.58501998169392e-09	Natural killer cell mediated cytotoxicity: CSF2
hsa04910__18	5.06970201701994e-10	DOWN	-6.218218612537	1.58501998169392e-09	Insulin signaling pathway: LIPE
hsa05321__74	5.23863397679992e-10	DOWN	-6.21307108057298	1.63511515654602e-09	Inflammatory bowel disease (IBD): IL5
hsa04668__138	5.50237770606536e-10	UP	6.20534978262695	1.7145883432333e-09	TNF signaling pathway: NFKB1*
hsa05321__81	5.59313827725194e-10	DOWN	-6.20277601664494	1.73998457333715e-09	Inflammatory bowel disease (IBD): IL13
hsa04917__40	5.68535911640666e-10	DOWN	-6.20020225066293	1.76575037681456e-09	Prolactin signaling pathway: TH
hsa05016__48	6.27065536906129e-10	DOWN	-6.18475965477086	1.9411139107852e-09	Huntington's disease: HIP1
hsa05016__46	6.27065536906129e-10	DOWN	-6.18475965477086	1.9411139107852e-09	Huntington's disease: HTT**
hsa04742__23 45	6.37339288805926e-10	UP	6.18218588878885	1.96967191392489e-09	Taste transduction: PKD1L3 PKD2L1
hsa04110__46	6.58495018087921e-10	UP	6.17703835682483	2.03171122986404e-09	Cell cycle: RB1
hsa05169__32	6.91459508165436e-10	DOWN	-6.1693170588788	2.12992199318501e-09	Epstein-Barr virus infection: CR2
hsa04022__49	7.26031915428714e-10	DOWN	-6.16159576093277	2.22184685519634e-09	cGMP-PKG signaling pathway: ATP1B4
hsa04152__61	7.26031915428714e-10	UP	6.16159576093277	2.22184685519634e-09	AMPK signaling pathway: RPS6KB1
hsa04931__149	7.26031915428714e-10	DOWN	-6.16159576093277	2.22184685519634e-09	Insulin resistance: ACACB*
hsa05205__195	7.26031915428714e-10	UP	6.16159576093277	2.22184685519634e-09	Proteoglycans in cancer: CDKN1A
hsa04919__44	7.37926448635462e-10	DOWN	-6.15902199495076	2.25457527965208e-09	Thyroid hormone signaling pathway: PFKFB2
hsa05030__77	7.87434475675714e-10	DOWN	-6.14872693102272	2.40193081135498e-09	Cocaine addiction: BDNF
hsa04918__14	8.96359468738653e-10	DOWN	-6.12813680316664	2.72975598340345e-09	Thyroid hormone synthesis: DUOX2
hsa04010__86	9.10967821800079e-10	UP	6.12556303718462	2.7652803508277e-09	MAPK signaling pathway: MAP4K2
hsa04912__19	9.10967821800079e-10	UP	6.12556303718462	2.7652803508277e-09	GnRH signaling pathway: MAPK7
hsa04024__9 95	9.40884378377819e-10	DOWN	-6.1204155052206	2.8468949226601e-09	cAMP signaling pathway: ATP1B4 FXYD1
hsa05215__30	9.40884378377819e-10	UP	6.1204155052206	2.8468949226601e-09	Prostate cancer: TP53
hsa05161__10	9.71758254687747e-10	UP	6.11526797325658	2.93558482404868e-09	Hepatitis B: CASP3
hsa04152__52	1.07042622152879e-09	DOWN	-6.09982537736452	3.22846046589502e-09	AMPK signaling pathway: PCK1
hsa04068__66	1.10543639856535e-09	DOWN	-6.0946778454005	3.32870992452611e-09	FoxO signaling pathway: BNIP3
hsa04020__7	1.17883789122519e-09	DOWN	-6.08438278147246	3.54405823617942e-09	Calcium signaling pathway: ADCY1
hsa05010__59	1.21729935761477e-09	DOWN	-6.07923524950844	3.65384264050824e-09	Alzheimer's disease: LRP1
hsa04151__32	1.31888367899818e-09	UP	6.06636641959839	3.94615037076047e-09	PI3K-Akt signaling pathway: BCL2L1
hsa05133__73	1.31888367899818e-09	DOWN	-6.06636641959839	3.94615037076047e-09	Pertussis: FOS
hsa04015__100 101 48	1.34016998324974e-09	UP	6.06379265361638	4.00346486252189e-09	Rap1 signaling pathway: PRKCI PARD6A PARD3
hsa04066__64	1.36179103234929e-09	UP	6.06121888763437	4.06159579330845e-09	HIF-1 signaling pathway: LTBR
hsa04024__115	1.45172619593584e-09	DOWN	-6.05092382370632	4.32296913179626e-09	cAMP signaling pathway: F2R
hsa04261__14 16	1.498838990051e-09	UP	6.0457762917423	4.44916028800288e-09	Adrenergic signaling in cardiomyocytes: TNNI3 TPM1
hsa04261__62	1.498838990051e-09	UP	6.0457762917423	4.44916028800288e-09	Adrenergic signaling in cardiomyocytes: BCL2
hsa04666__41	1.54744070100667e-09	UP	6.04062875977828	4.58618466433997e-09	Fc gamma R-mediated phagocytosis: MARCKS
hsa05200__192	1.57231413698998e-09	DOWN	-6.03805499379627	4.65256419433729e-09	Pathways in cancer: PTGS2
hsa05200__183	1.64929513911787e-09	UP	6.03033369585024	4.87268170818e-09	Pathways in cancer: BMP2
hsa04115__23	1.7026434413577e-09	UP	6.02518616388622	5.01452511960992e-09	p53 signaling pathway: PTEN
hsa04210__119	1.7026434413577e-09	DOWN	-6.02518616388622	5.01452511960992e-09	Apoptosis: BCL2*
hsa04310__22	1.81441956697322e-09	DOWN	-6.01489109995818	5.33535894576319e-09	Wnt signaling pathway: ROCK2
hsa04668__102	1.87297639261128e-09	UP	6.00974356799416	5.49894162768219e-09	TNF signaling pathway: AKT3
hsa05152__76	1.96425872550785e-09	UP	6.00202227004813	5.75794406432019e-09	Tuberculosis: TNF*
hsa04062__53	2.02750644392075e-09	UP	5.99687473808411	5.93408817465279e-09	Chemokine signaling pathway: NFKB1
hsa04210__4	2.09273657311588e-09	DOWN	-5.99172720612009	6.10598139888936e-09	Apoptosis: DFFA
hsa04723__46	2.09273657311588e-09	DOWN	-5.99172720612009	6.10598139888936e-09	Retrograde endocannabinoid signaling: ADCY1
hsa04650__36	2.22938725723609e-09	UP	5.98143214219205	6.49460256797924e-09	Natural killer cell mediated cytotoxicity: CASP3
hsa04612__18	2.41246507291146e-09	UP	5.96856331228199	7.01706172136322e-09	Antigen processing and presentation: KIR2DS2
hsa04022__45	2.48972621178781e-09	DOWN	-5.96341578031797	7.20831363936716e-09	cGMP-PKG signaling pathway: CREB3
hsa04664__46	2.48972621178781e-09	UP	5.96341578031797	7.20831363936716e-09	Fc epsilon RI signaling pathway: PLA2G4B
hsa05164__99	2.48972621178781e-09	DOWN	-5.96341578031797	7.20831363936716e-09	Influenza A: FDPS
hsa04650__25	2.61015545707405e-09	UP	5.95569448237194	7.54535708283405e-09	Natural killer cell mediated cytotoxicity: SH2D1B
hsa05200__209	2.65154511524608e-09	DOWN	-5.95312071638993	7.65323083187002e-09	Pathways in cancer: FIGF**
hsa04723__67	2.69357368696466e-09	DOWN	-5.95054695040792	7.76261496596104e-09	Retrograde endocannabinoid signaling: PRKACA
hsa03320__58	2.73625075214574e-09	DOWN	-5.94797318442591	7.84948879890359e-09	PPAR signaling pathway: CYP8B1
hsa04115__64	2.73625075214574e-09	UP	5.94797318442591	7.84948879890359e-09	p53 signaling pathway: PMAIP1
hsa04931__46	2.73625075214574e-09	DOWN	-5.94797318442591	7.84948879890359e-09	Insulin resistance: PIK3R5*
hsa03320__56	2.82358938030421e-09	DOWN	-5.94282565246189	8.07537967365543e-09	PPAR signaling pathway: FADS2
hsa05140__62	2.82358938030421e-09	DOWN	-5.94282565246189	8.07537967365543e-09	Leishmaniasis: C00584
hsa04064__115	2.86827080674106e-09	UP	5.94025188647988	8.17827138978218e-09	NF-kappa B signaling pathway: XIAP
hsa04370__15	2.86827080674106e-09	DOWN	-5.94025188647988	8.17827138978218e-09	VEGF signaling pathway: PLA2G4B
hsa04722__38	3.00648576340675e-09	DOWN	-5.93253058853385	8.55937386278982e-09	Neurotrophin signaling pathway: ATF4
hsa03320__61	3.10220946463589e-09	DOWN	-5.92738305656983	8.81853492292109e-09	PPAR signaling pathway: APOA1
hsa05166__83	3.15117768487924e-09	UP	5.92480929058782	8.94420373094878e-09	HTLV-I infection: NFKB2
hsa04810__48	3.20089818241217e-09	DOWN	-5.92223552460581	9.07162546719829e-09	Regulation of actin cytoskeleton: IQGAP2
hsa04530__11 36 14	3.30264106142622e-09	DOWN	-5.91708799264179	9.33182339010505e-09	Tight junction: TJP1 CTNNB1 CTNNA1
hsa04917__37	3.30264106142622e-09	DOWN	-5.91708799264179	9.33182339010505e-09	Prolactin signaling pathway: TNFSF11
hsa04724__13	3.51561281211795e-09	UP	5.90679292871375	9.90393271938614e-09	Glutamatergic synapse: GRM5
hsa04210__50	3.5156589269987e-09	DOWN	-5.90679292871375	9.90393271938614e-09	Apoptosis: SPTA1
hsa04660__26	3.74202943287311e-09	UP	5.8964978647857	1.05258582400727e-08	T cell receptor signaling pathway: GRB2
hsa05164__90	3.98256407020554e-09	DOWN	-5.88620280085766	1.11857068578718e-08	Influenza A: MAPK1
hsa04020__64	4.10840949363624e-09	DOWN	-5.88105526889364	1.15047711453688e-08	Calcium signaling pathway: C01330*
hsa04020__12	4.10840949363624e-09	DOWN	-5.88105526889364	1.15047711453688e-08	Calcium signaling pathway: C01330
hsa04660__30	4.172775236289e-09	UP	5.87848150291163	1.16676259955164e-08	T cell receptor signaling pathway: CD40LG
hsa05200__53	4.65163171920427e-09	UP	5.86046514103756	1.29679762616985e-08	Pathways in cancer: BCL2L1
hsa05216__15	4.65163171920427e-09	DOWN	-5.86046514103756	1.29679762616985e-08	Thyroid cancer: CCND1
hsa04971__37	4.79799921150872e-09	DOWN	-5.85531760907354	1.33562081754443e-08	Gastric acid secretion: KCNQ1
hsa04115__56	4.94884443083258e-09	UP	5.85017007710952	1.37557377004947e-08	p53 signaling pathway: SESN3
hsa04360__108	5.18379968005315e-09	DOWN	-5.84244877916349	1.43663120926547e-08	Axon guidance: CFL1
hsa05134__6	5.18379968005315e-09	UP	5.84244877916349	1.43663120926547e-08	Legionellosis: IL1B
hsa05132__8	5.68671293524393e-09	DOWN	-5.82700618327142	1.57368683436279e-08	Salmonella infection: TJP1
hsa04650__16	5.86466535854692e-09	UP	5.8218586513074	1.6205450306926e-08	Natural killer cell mediated cytotoxicity: PRKCA
hsa04976__37	5.95566135002105e-09	UP	5.81928488532539	1.64327278659171e-08	Bile secretion: ABCB11
hsa04064__55	6.23696701881827e-09	DOWN	-5.81156358737936	1.71836671970081e-08	NF-kappa B signaling pathway: CXCL12
hsa04064__130	6.33357606073963e-09	UP	5.80898982139735	1.7424289045578e-08	NF-kappa B signaling pathway: TNF*
hsa03320__40	6.53118017396232e-09	DOWN	-5.80384228943333	1.79416484603438e-08	PPAR signaling pathway: FABP4
hsa04742__27	6.63221804887889e-09	DOWN	-5.80126852345132	1.81926098012313e-08	Taste transduction: CALHM1
hsa04014__58 59	6.73477550949913e-09	UP	5.79869475746931	1.84470017235406e-08	Ras signaling pathway: STK4 STK4
hsa04550__25	7.16064921641151e-09	DOWN	-5.78839969354127	1.95849488757456e-08	Signaling pathways regulating pluripotency of stem cells: MAPK1
hsa05212__14	7.49712789250607e-09	DOWN	-5.78067839559524	2.04754408575856e-08	Pancreatic cancer: MAPK1
hsa04972__18	7.72993632899405e-09	DOWN	-5.77553086363122	2.10806246185484e-08	Pancreatic secretion: PRKCA
hsa04064__50	7.96976840478359e-09	UP	5.7703833316672	2.17031809167947e-08	NF-kappa B signaling pathway: NFKBIA*
hsa05133__59	8.34313662925093e-09	UP	5.76266203372117	2.26870531495839e-08	Pertussis: C3
hsa03320__63	8.4713306789022e-09	DOWN	-5.76008826773916	2.2969163557947e-08	PPAR signaling pathway: DBI
hsa04062__43	8.4713306789022e-09	UP	5.76008826773916	2.2969163557947e-08	Chemokine signaling pathway: STAT1
hsa03320__29	8.60143894600943e-09	UP	5.75751450175715	2.32883339762993e-08	PPAR signaling pathway: OLR1
hsa04064__51	8.86750935509086e-09	UP	5.75236696979312	2.39741727744111e-08	NF-kappa B signaling pathway: TNFAIP3
hsa05161__32	9.28167702608779e-09	DOWN	-5.74464567184709	2.50578608218663e-08	Hepatitis B: STAT3
hsa04630__24	9.42386623270367e-09	DOWN	-5.74207190586508	2.54052290548783e-08	Jak-STAT signaling pathway: MCL1
hsa05205__146	9.56817194347656e-09	DOWN	-5.73949813988307	2.57572995441153e-08	Proteoglycans in cancer: PTK2
hsa04725__64	1.01671769328349e-08	DOWN	-5.72920307595503	2.73306515834002e-08	Cholinergic synapse: KCNJ3
hsa04668__116	1.03225317776657e-08	UP	5.72662930997302	2.76690973041853e-08	TNF signaling pathway: PGAM5
hsa05110__52	1.03225317776657e-08	DOWN	-5.72662930997302	2.76690973041853e-08	Vibrio cholerae infection: ADCY3
hsa04071__69	1.08025667336667e-08	UP	5.71890801202699	2.89145625250138e-08	Sphingolipid signaling pathway: RAC1
hsa04014__62	1.11345696086867e-08	UP	5.71376048006297	2.97185458731851e-08	Ras signaling pathway: RASSF5
hsa04210__70	1.11345696086867e-08	UP	5.71376048006297	2.97185458731851e-08	Apoptosis: CFLAR*
hsa04012__31	1.14764800051482e-08	UP	5.70861294809895	3.05876679853524e-08	ErbB signaling pathway: BAD
hsa04350__11	1.18285842502332e-08	DOWN	-5.70346541613493	3.14814586489917e-08	TGF-beta signaling pathway: SMAD4*
hsa05132__86	1.20085507217618e-08	DOWN	-5.70089165015292	3.191522886307e-08	Salmonella infection: MYH9
hsa05200__202	1.21911766595339e-08	DOWN	-5.69831788417091	3.23548318407686e-08	Pathways in cancer: FIGF*
hsa04933__29	1.31455494604223e-08	UP	5.68544905426086	3.48384872159852e-08	AGE-RAGE signaling pathway in diabetic complications: ICAM1
hsa04722__53	1.37526060019596e-08	DOWN	-5.67772775631482	3.63959812361721e-08	Neurotrophin signaling pathway: JUN
hsa04151__98	1.39609450684487e-08	UP	5.67515399033281	3.68435614938415e-08	PI3K-Akt signaling pathway: BCL2L1*
hsa04530__5 15	1.39609450684487e-08	DOWN	-5.67515399033281	3.68435614938415e-08	Tight junction: IGSF5 MPDZ
hsa04064__128	1.48253883657334e-08	UP	5.66485892640477	3.90699926216172e-08	NF-kappa B signaling pathway: IL1B*
hsa03320__46	1.50494937995036e-08	DOWN	-5.66228516042276	3.96050404051363e-08	PPAR signaling pathway: APOA2
hsa04931__40	1.52768883699437e-08	DOWN	-5.65971139444075	4.01472353106632e-08	Insulin resistance: PRKCZ
hsa04650__35	1.59792775696266e-08	UP	5.65199009649472	4.18759589307229e-08	Natural killer cell mediated cytotoxicity: BID
hsa04720__4 15	1.59792775696266e-08	DOWN	-5.65199009649472	4.18759589307229e-08	Long-term potentiation: CREBBP ATF4
hsa04914__30	1.64646591392871e-08	UP	5.6468425645307	4.30878753798334e-08	Progesterone-mediated oocyte maturation: CDK1*
hsa05120__19	1.77423447813409e-08	UP	5.63397373462065	4.63669900474819e-08	Epithelial cell signaling in Helicobacter pylori infection: CXCL1
hsa04390__95	1.88331539686985e-08	DOWN	-5.62367867069261	4.90811321874958e-08	Hippo signaling pathway: AFP
hsa05161__194	1.88331539686985e-08	UP	5.62367867069261	4.90811321874958e-08	Hepatitis B: TNF*
hsa05152__78	2.15308599918066e-08	UP	5.60051477685451	5.60339140229981e-08	Tuberculosis: IL1A
hsa04917__56	2.25107741228707e-08	DOWN	-5.59279347890848	5.85031045323292e-08	Prolactin signaling pathway: LHCGR
hsa04390__80	2.28469299431669e-08	DOWN	-5.59021971292647	5.92947256397936e-08	Hippo signaling pathway: BIRC2
hsa05222__35	2.31879561750261e-08	DOWN	-5.58764594694446	6.00967857281022e-08	Small cell lung cancer: NOS2
hsa04380__69	2.49685656296535e-08	UP	5.57477711703441	6.4533610478843e-08	Osteoclast differentiation: NFKB2
hsa04921__41	2.49685656296535e-08	DOWN	-5.57477711703441	6.4533610478843e-08	Oxytocin signaling pathway: PTGS2
hsa04210__59	2.57173640882171e-08	UP	5.56962958507039	6.62865941313579e-08	Apoptosis: PMAIP1
hsa04922__37	2.57173640882171e-08	DOWN	-5.56962958507039	6.62865941313579e-08	Glucagon signaling pathway: PYGB
hsa03320__9	2.64879360336344e-08	DOWN	-5.56448205310637	6.81792216536973e-08	PPAR signaling pathway: PCK1
hsa04664__47	2.76859627648926e-08	UP	5.55676075516034	7.11654227568171e-08	Fc epsilon RI signaling pathway: MAPK8
hsa04921__67	2.80968654277952e-08	UP	5.55418698917833	7.21229646705289e-08	Oxytocin signaling pathway: RYR1
hsa05133__27	2.93653922424818e-08	UP	5.5464656912323	7.52763601959391e-08	Pertussis: IRF3
hsa04970__21	3.11434855332202e-08	DOWN	-5.53617062730426	7.97256257723717e-08	Salivary secretion: ITPR1
hsa04151__109	3.25451591330679e-08	UP	5.52844932935822	8.32004816476662e-08	PI3K-Akt signaling pathway: RXRA
hsa04068__60	3.30258394629689e-08	DOWN	-5.52587556337621	8.43146091724436e-08	FoxO signaling pathway: RAG1
hsa04620__46	3.40079462602786e-08	UP	5.52072803141219	8.67041126500183e-08	Toll-like receptor signaling pathway: TNF
hsa04662__10	3.45095646010789e-08	UP	5.51815426543018	8.78637830425844e-08	B cell receptor signaling pathway: GSK3B
hsa05166__74	3.5018356286834e-08	DOWN	-5.51558049944817	8.90385540770785e-08	HTLV-I infection: NFKB1
hsa04742__54	3.60553788138874e-08	DOWN	-5.51043296748415	9.1310936057839e-08	Taste transduction: P2RX2*
hsa04742__40	3.60553788138874e-08	DOWN	-5.51043296748415	9.1310936057839e-08	Taste transduction: P2RX2
hsa04340__46	3.60578576662674e-08	DOWN	-5.51043296748415	9.1310936057839e-08	Hedgehog signaling pathway: PRKACA
hsa04668__153	3.76734321693221e-08	UP	5.50271166953812	9.50179584512164e-08	TNF signaling pathway: MAPK14*
hsa04910__20	3.76734321693221e-08	DOWN	-5.50271166953812	9.50179584512164e-08	Insulin signaling pathway: PKLR
hsa05200__220	3.76734321693221e-08	UP	5.50271166953812	9.50179584512164e-08	Pathways in cancer: CSF1R*
hsa04066__59	3.87892499601637e-08	DOWN	-5.4975641375741	9.77010732910825e-08	HIF-1 signaling pathway: NOS2
hsa05212__27	3.93591113408246e-08	DOWN	-5.49499037159209	9.90037084463312e-08	Pancreatic cancer: BCL2L1*
hsa04022__51	3.99370875104373e-08	DOWN	-5.49241660561008	1.00323245230096e-07	cGMP-PKG signaling pathway: GTF2I
hsa04024__111	4.42197039686911e-08	DOWN	-5.47440024373601	1.10933009021589e-07	cAMP signaling pathway: JUN
hsa04152__27	4.89461193561364e-08	DOWN	-5.45638388186193	1.2262634436024e-07	AMPK signaling pathway: ADIPOR1
hsa04022__59	5.33840258100993e-08	DOWN	-5.44094128596987	1.33566690409023e-07	cGMP-PKG signaling pathway: NPPB
hsa05321__94	5.416063085955e-08	UP	5.43836751998786	1.3532955503337e-07	Inflammatory bowel disease (IBD): IL22
hsa04970__28	5.49478733640531e-08	DOWN	-5.43579375400585	1.37114281608308e-07	Salivary secretion: AQP5
hsa05150__14	5.73773519318717e-08	UP	5.42807245605982	1.42986796127304e-07	Staphylococcus aureus infection: FPR1
hsa04152__57	6.07802153884832e-08	UP	5.41777739213178	1.51266257900609e-07	AMPK signaling pathway: ACACA*
hsa05200__187	6.2553831706426e-08	UP	5.41262986016776	1.55474404466104e-07	Pathways in cancer: WNT16*
hsa04910__14	6.53086163493617e-08	DOWN	-5.40490856222173	1.61892994881861e-07	Insulin signaling pathway: C00369
hsa05169__30	6.53086163493617e-08	UP	5.40490856222173	1.61892994881861e-07	Epstein-Barr virus infection: FGR
hsa04612__39	6.72100504597715e-08	UP	5.39976103025771	1.66386936513716e-07	Antigen processing and presentation: PSME3
hsa04360__125	6.81807696737992e-08	UP	5.3971872642757	1.68125546216626e-07	Axon guidance: ENAH*
hsa05110__12	6.81807696737992e-08	DOWN	-5.3971872642757	1.68125546216626e-07	Vibrio cholerae infection: C00080
hsa05120__35	6.81807696737992e-08	DOWN	-5.3971872642757	1.68125546216626e-07	Epithelial cell signaling in Helicobacter pylori infection: C00080
hsa04213__55	7.11751136959447e-08	DOWN	-5.38946596632967	1.75049788788848e-07	Longevity regulating pathway - multiple species: CRYAB
hsa04520__64	7.11751136959447e-08	DOWN	-5.38946596632967	1.75049788788848e-07	Adherens junction: CTNND1**
hsa04650__110 111	7.42966606971377e-08	UP	5.38174466838363	1.82488137843035e-07	Natural killer cell mediated cytotoxicity: ITGAL ITGB2
hsa05134__73	7.64509247064961e-08	UP	5.37659713641961	1.87534317915804e-07	Legionellosis: CXCL1
hsa04380__68	7.86656284811196e-08	DOWN	-5.37144960445559	1.92715405366393e-07	Osteoclast differentiation: TGFBR1
hsa05110__46	8.09424073829352e-08	DOWN	-5.36630207249157	1.98034874313197e-07	Vibrio cholerae infection: PLCG1
hsa04912__14	8.32829392751652e-08	UP	5.36115454052755	2.03496284652842e-07	GnRH signaling pathway: ATF4
hsa04540__14 31	8.56889455777589e-08	DOWN	-5.35600700856353	2.09103284078713e-07	Gap junction: GJA1 TJP1
hsa04015__92	9.19971500335643e-08	UP	5.34313817865348	2.24205765127195e-07	Rap1 signaling pathway: C00076*
hsa04062__33	9.73746586923438e-08	UP	5.33284311472544	2.35782195467673e-07	Chemokine signaling pathway: WAS
hsa04540__14 16	9.73746586923438e-08	DOWN	-5.33284311472544	2.35782195467673e-07	Gap junction: GJA1 GJA1
hsa04540__14 15	9.73746586923438e-08	DOWN	-5.33284311472544	2.35782195467673e-07	Gap junction: GJA1 GJA1*
hsa04913__47	9.73746586923438e-08	DOWN	-5.33284311472544	2.35782195467673e-07	Ovarian steroidogenesis: INSR
hsa04913__51	9.73746586923438e-08	DOWN	-5.33284311472544	2.35782195467673e-07	Ovarian steroidogenesis: INSR*
hsa04360__123	1.01602111320198e-07	UP	5.32512181677941	2.45701888250518e-07	Axon guidance: ENAH
hsa04022__46	1.0600696176482e-07	DOWN	-5.31740051883338	2.5602452590758e-07	cGMP-PKG signaling pathway: VASP
hsa05100__55	1.09045612766742e-07	DOWN	-5.31225298686936	2.63025297033001e-07	Bacterial invasion of epithelial cells: ACTB*
hsa04213__62	1.12168481280835e-07	DOWN	-5.30710545490533	2.69865014502802e-07	Longevity regulating pathway - multiple species: CAT*
hsa05162__28 34	1.12168481280835e-07	UP	5.30710545490533	2.69865014502802e-07	Measles: IRF9 STAT1
hsa05213__29	1.13762197709413e-07	DOWN	-5.30453168892332	2.73349321606121e-07	Endometrial cancer: CCND1
hsa04152__89	1.18675924814687e-07	DOWN	-5.29681039097729	2.8479190641992e-07	AMPK signaling pathway: CFTR
hsa05205__69	1.22065172296763e-07	UP	5.29166285901327	2.9255160554288e-07	Proteoglycans in cancer: MAPK1*
hsa05020__62	1.25547985066116e-07	DOWN	-5.28651532704925	3.00515495463989e-07	Prion diseases: NOTCH1
hsa04066__48	1.30953099338999e-07	DOWN	-5.27879402910322	3.1305454663865e-07	HIF-1 signaling pathway: PFKFB3
hsa05132__13	1.34680850359125e-07	DOWN	-5.2736464971392	3.2114888048832e-07	Salmonella infection: FOS
hsa05321__92	1.34680850359125e-07	UP	5.2736464971392	3.2114888048832e-07	Inflammatory bowel disease (IBD): IL17F
hsa04620__20	1.40465613847152e-07	UP	5.26592519919317	3.34518236272241e-07	Toll-like receptor signaling pathway: IFNB1*
hsa04728__70 73	1.46490370657995e-07	DOWN	-5.25820390124714	3.48424565147306e-07	Dopaminergic synapse: KIF5A GRIA1
hsa04210__105	1.52764703354255e-07	DOWN	-5.25048260330111	3.62430401013441e-07	Apoptosis: ACTB
hsa04720__32	1.52764703354255e-07	DOWN	-5.25048260330111	3.62430401013441e-07	Long-term potentiation: ITPR1
hsa04010__68	1.54913317685684e-07	UP	5.2479088373191	3.66602171198237e-07	MAPK signaling pathway: ATF2
hsa04150__56	1.54913317685684e-07	UP	5.2479088373191	3.66602171198237e-07	mTOR signaling pathway: EIF4B
hsa05120__53	1.57091142761181e-07	DOWN	-5.24533507133709	3.7128837389718e-07	Epithelial cell signaling in Helicobacter pylori infection: GIT1
hsa04530__20 22	1.68431986182509e-07	DOWN	-5.23246624142703	3.97592590498662e-07	Tight junction: ACTB MYL12B
hsa04024__118	1.80562558450374e-07	DOWN	-5.21959741151698	4.2569265662265e-07	cAMP signaling pathway: MYL9
hsa04912__17	1.88241816762509e-07	UP	5.21187611357095	4.43241069795431e-07	GnRH signaling pathway: MAPK14
hsa04650__15	1.90871020750018e-07	UP	5.20930234758894	4.4886939673252e-07	Natural killer cell mediated cytotoxicity: TNF
hsa05161__214	2.01747270816584e-07	UP	5.1990072836609	4.73853902330453e-07	Hepatitis B: CDKN1B
hsa04072__36	2.13221366097543e-07	DOWN	-5.18871221973286	4.9893268604892e-07	Phospholipase D signaling pathway: MTOR
hsa04211__42	2.13221366097543e-07	DOWN	-5.18871221973286	4.9893268604892e-07	Longevity regulating pathway - mammal: PPARGC1A
hsa04919__39	2.13221366097543e-07	DOWN	-5.18871221973286	4.9893268604892e-07	Thyroid hormone signaling pathway: ESR1
hsa04066__89	2.16186969473211e-07	UP	5.18613845375085	5.05242929900702e-07	HIF-1 signaling pathway: CDKN1A
hsa04071__59 60	2.25324886032536e-07	UP	5.17841715580482	5.25944671869734e-07	Sphingolipid signaling pathway: TP53 BCL2
hsa04670__2	2.31622982951138e-07	UP	5.1732696238408	5.3997467117269e-07	Leukocyte transendothelial migration: MMP2
hsa04917__65	2.34835480446227e-07	DOWN	-5.17069585785879	5.46785461906395e-07	Prolactin signaling pathway: CYP17A1
hsa04210__114	2.55033686876116e-07	UP	5.15525326196672	5.93079576287402e-07	Apoptosis: HRK
hsa04611__25	2.62131891213786e-07	UP	5.1501057300027	6.08832909259214e-07	Platelet activation: ORAI1
hsa05205__142	2.65752179904394e-07	UP	5.14753196402069	6.16479439555995e-07	Proteoglycans in cancer: CTNNB1
hsa04916__15	2.73138187775383e-07	DOWN	-5.14238443205667	6.32831880184889e-07	Melanogenesis: MITF*
hsa04024__92	2.76905152514811e-07	UP	5.13981066607466	6.40769435437598e-07	cAMP signaling pathway: GRIN3A
hsa04728__64	2.92480974536311e-07	DOWN	-5.12951560214662	6.75149571441926e-07	Dopaminergic synapse: SCN1A
hsa05150__66	2.92480974536311e-07	UP	5.12951560214662	6.75149571441926e-07	Staphylococcus aureus infection: IL10
hsa04210__10	3.00582846381305e-07	UP	5.1243680701826	6.93000206564996e-07	Apoptosis: BIRC2
hsa04010__12	3.04714624747893e-07	UP	5.12179430420059	7.00806340148458e-07	MAPK signaling pathway: PLA2G4B
hsa05160__77	3.04714624747893e-07	UP	5.12179430420059	7.00806340148458e-07	Hepatitis C: NFKB1*
hsa04725__18	3.08901216137686e-07	DOWN	-5.11922053821858	7.08700103934936e-07	Cholinergic synapse: ITPR1
hsa05120__50	3.08901216137686e-07	DOWN	-5.11922053821858	7.08700103934936e-07	Epithelial cell signaling in Helicobacter pylori infection: EGFR
hsa04270__48	3.21796901788867e-07	DOWN	-5.11149924027255	7.37385827391807e-07	Vascular smooth muscle contraction: KCNMB2*
hsa04151__37	3.30681136127063e-07	DOWN	-5.10635170830853	7.56820773182401e-07	PI3K-Akt signaling pathway: G6PC
hsa04726__41	3.35211587909126e-07	UP	5.10377794232652	7.65325119904311e-07	Serotonergic synapse: HTR3C
hsa04742__57	3.35211587909126e-07	UP	5.10377794232652	7.65325119904311e-07	Taste transduction: HTR3C
hsa04390__58	3.39801928739617e-07	DOWN	-5.10120417634451	7.74863864201141e-07	Hippo signaling pathway: SMAD7
hsa04932__28	3.58777539393743e-07	UP	5.09090911241647	8.17143026085871e-07	Non-alcoholic fatty liver disease (NAFLD): GSK3A
hsa04933__25	3.63678925116125e-07	UP	5.08833534643446	8.27303511250846e-07	AGE-RAGE signaling pathway in diabetic complications: IL1A
hsa04064__133	3.94472714918421e-07	UP	5.07289275054239	8.96268719869061e-07	NF-kappa B signaling pathway: CXCL2
hsa04933__57	3.99843794412351e-07	UP	5.07031898456038	9.07374987561363e-07	AGE-RAGE signaling pathway in diabetic complications: FIGF
hsa04725__61	4.10798441712801e-07	DOWN	-5.06517145259636	9.31110098888243e-07	Cholinergic synapse: FOS
hsa05132__54	4.16383799675974e-07	UP	5.06259768661435	9.42632722398983e-07	Salmonella infection: IL1B
hsa03320__60	4.2204239195044e-07	UP	5.06002392063234	9.54293206347626e-07	PPAR signaling pathway: CYP27A1
hsa05161__100	4.33582979574977e-07	UP	5.05487638866832	9.79209637766084e-07	Hepatitis B: MMP9*
hsa04919__43	4.3946685286626e-07	DOWN	-5.05230262268631	9.913063823958e-07	Thyroid hormone signaling pathway: TBC1D4
hsa05166__5	4.57584296710563e-07	DOWN	-5.04458132474028	1.03093632316445e-06	HTLV-I infection: SLC2A1
hsa04912__46	4.63781982878562e-07	UP	5.04200755875827	1.04364831835787e-06	GnRH signaling pathway: JUN
hsa05020__48	4.70060599367647e-07	DOWN	-5.03943379277626	1.05524954147169e-06	Prion diseases: SOD1
hsa05152__23	4.70060599367647e-07	DOWN	-5.03943379277626	1.05524954147169e-06	Tuberculosis: PPP3CA
hsa04530__30	4.82864694123765e-07	UP	5.03428626081224	1.08012233364114e-06	Tight junction: AKT3
hsa04920__26	4.82864694123765e-07	DOWN	-5.03428626081224	1.08012233364114e-06	Adipocytokine signaling pathway: NPY
hsa05150__69	4.82864694123765e-07	UP	5.03428626081224	1.08012233364114e-06	Staphylococcus aureus infection: FPR2
hsa04350__32	5.02703578106869e-07	UP	5.02656496286621	1.12316292896886e-06	TGF-beta signaling pathway: RPS6KB1
hsa05031__96	5.09489514626652e-07	DOWN	-5.0239911968842	1.1369724441609e-06	Amphetamine addiction: PDYN
hsa04912__33	5.30381506111803e-07	UP	5.01626989893817	1.18219080662405e-06	GnRH signaling pathway: ELK1
hsa04924__58	5.52098343771658e-07	DOWN	-5.00854860099213	1.22768377271828e-06	Renin secretion: PPP3CA
hsa05031__59	5.52098343771658e-07	DOWN	-5.00854860099213	1.22768377271828e-06	Amphetamine addiction: PPP3CA
hsa03320__7	5.59525952825315e-07	DOWN	-5.00597483501012	1.24272962808365e-06	PPAR signaling pathway: AQP7
hsa03320__33	5.74671247936691e-07	DOWN	-5.0008273030461	1.27486100929521e-06	PPAR signaling pathway: CYP7A1
hsa04010__107	5.82391343968665e-07	UP	4.99825353706409	1.29046383881736e-06	MAPK signaling pathway: MAP3K2
hsa04620__12	6.14283506981369e-07	UP	4.98795847313605	1.35952733759481e-06	Toll-like receptor signaling pathway: NFKB1
hsa04152__56	6.4785569395101e-07	UP	4.97766340920801	1.43214217521641e-06	AMPK signaling pathway: FASN
hsa05161__227	6.56521088631009e-07	UP	4.975089643226	1.44959239193615e-06	Hepatitis B: MYD88*
hsa05200__215	6.92312965779624e-07	UP	4.96479457929796	1.52503641582639e-06	Pathways in cancer: CSF1R
hsa05231__34	6.92312965779624e-07	UP	4.96479457929796	1.52503641582639e-06	Choline metabolism in cancer: PLD1
hsa05014__2	7.1090679775708e-07	DOWN	-4.95964704733394	1.56233201518778e-06	Amyotrophic lateral sclerosis (ALS): SLC1A2
hsa05162__13	7.1090679775708e-07	UP	4.95964704733394	1.56233201518778e-06	Measles: IRF7
hsa04933__27	7.39702537525502e-07	UP	4.95192574938791	1.62182154960375e-06	AGE-RAGE signaling pathway in diabetic complications: TNF
hsa05200__212	7.39702537525502e-07	DOWN	-4.95192574938791	1.62182154960375e-06	Pathways in cancer: CCND1***
hsa04064__95	7.59520493266817e-07	UP	4.94677821742389	1.66333217581393e-06	NF-kappa B signaling pathway: BCL2L1**
hsa04923__52 53	7.90209452116278e-07	UP	4.93905691947785	1.72852568163735e-06	Regulation of lipolysis in adipocytes: PNPLA2 ABHD5*
hsa05205__233 234	8.00701974840343e-07	DOWN	-4.93648315349584	1.74944071014536e-06	Proteoglycans in cancer: ITGA2 C00925
hsa04912__15	8.3299089365032e-07	UP	4.92876185554981	1.8178744357363e-06	GnRH signaling pathway: CAMK2A
hsa04923__38	8.55209638641925e-07	DOWN	-4.92361432358579	1.8641982726313e-06	Regulation of lipolysis in adipocytes: PDE3B
hsa04917__45	8.77998550222596e-07	DOWN	-4.91846679162177	1.91165617134213e-06	Prolactin signaling pathway: SLC2A2
hsa04810__32	9.132817206675e-07	DOWN	-4.91074549367574	1.9838801770338e-06	Regulation of actin cytoskeleton: PXN
hsa05219__19	9.132817206675e-07	DOWN	-4.91074549367574	1.9838801770338e-06	Bladder cancer: TP53
hsa04910__24	9.37558070383773e-07	DOWN	-4.90559796171172	2.03426283400821e-06	Insulin signaling pathway: ACACA
hsa04710__23	1.01417219195527e-06	UP	4.89015536581966	2.19795795695957e-06	Circadian rhythm: BHLHE41
hsa04024__31	1.06855888456641e-06	DOWN	-4.87986030189162	2.31049728895316e-06	cAMP signaling pathway: C00165
hsa04024__32	1.06855888456641e-06	DOWN	-4.87986030189162	2.31049728895316e-06	cAMP signaling pathway: C01245
hsa04931__61	1.08258798405449e-06	DOWN	-4.87728653590961	2.33814117475676e-06	Insulin resistance: ACACB
hsa04722__34	1.09679425357106e-06	UP	4.8747127699276	2.36610379157294e-06	Neurotrophin signaling pathway: GSK3B
hsa04152__54	1.14049762721976e-06	DOWN	-4.86699147198157	2.4575631210389e-06	AMPK signaling pathway: SLC2A4*
hsa04916__6	1.1554342460898e-06	DOWN	-4.86441770599956	2.48689684811309e-06	Melanogenesis: DCT
hsa04360__33 134	1.170558994866e-06	DOWN	-4.86184394001755	2.5165679077268e-06	Axon guidance: NCK1 PAK4
hsa04014__104	1.18587414163277e-06	UP	4.85927017403553	2.54658001386053e-06	Ras signaling pathway: BRAP*
hsa04920__9	1.23298504261373e-06	DOWN	-4.8515488760895	2.64472476606301e-06	Adipocytokine signaling pathway: G6PC
hsa04930__8	1.24908498669498e-06	DOWN	-4.84897511010749	2.67620375142517e-06	Type II diabetes mellitus: C00022
hsa04931__67	1.2653701049345e-06	UP	4.84640134412548	2.70800732024136e-06	Insulin resistance: IKBKB**
hsa04068__53	1.33266570828132e-06	DOWN	-4.83610628019744	2.84231426317888e-06	FoxO signaling pathway: SOD2
hsa04621__29	1.33266570828132e-06	UP	4.83610628019744	2.84231426317888e-06	NOD-like receptor signaling pathway: CASP5
hsa04917__71	1.33266570828132e-06	DOWN	-4.83610628019744	2.84231426317888e-06	Prolactin signaling pathway: CCND1*
hsa04024__93	1.35001544417017e-06	UP	4.83353251421543	2.87279617168262e-06	cAMP signaling pathway: ORAI1
hsa05205__215 216	1.35001544417017e-06	DOWN	-4.83353251421543	2.87279617168262e-06	Proteoglycans in cancer: EIF4B RPS6
hsa04024__34	1.36758230722291e-06	UP	4.83095874823342	2.90360130539192e-06	cAMP signaling pathway: ATP2B1
hsa04210__99	1.36758230722291e-06	UP	4.83095874823342	2.90360130539192e-06	Apoptosis: BID**
hsa04261__15 17	1.51625201858947e-06	DOWN	-4.81036862037734	3.2119927203265e-06	Adrenergic signaling in cardiomyocytes: ACTC1 MYH6
hsa05133__96	1.51625201858947e-06	UP	4.81036862037734	3.2119927203265e-06	Pertussis: IL1B
hsa04620__34	1.55577971247548e-06	UP	4.80522108841332	3.29201585556468e-06	Toll-like receptor signaling pathway: IL1B
hsa05231__21	1.59629704667843e-06	UP	4.8000735564493	3.3739506757129e-06	Choline metabolism in cancer: PCYT1A
hsa05142__67	1.61693420702768e-06	UP	4.79749979046729	3.4137296348371e-06	Chagas disease (American trypanosomiasis): IFNGR1*
hsa04014__37	1.65898056332689e-06	UP	4.79235225850327	3.49856843826176e-06	Ras signaling pathway: FASLG
hsa04115__29	1.70207676386893e-06	DOWN	-4.78720472653924	3.58542851940553e-06	p53 signaling pathway: IGF1
hsa05200__146 147	1.74623264509805e-06	DOWN	-4.78205719457522	3.66205325111527e-06	Pathways in cancer: RARB RXRA
hsa05222__14 15	1.74623264509805e-06	DOWN	-4.78205719457522	3.66205325111527e-06	Small cell lung cancer: RXRA RARB
hsa05223__29 34	1.74623264509805e-06	DOWN	-4.78205719457522	3.66205325111527e-06	Non-small cell lung cancer: RARB RXRA
hsa04261__34	1.74624785151638e-06	UP	4.78205719457522	3.66205325111527e-06	Adrenergic signaling in cardiomyocytes: AKT3
hsa04022__23	1.76874445859233e-06	UP	4.77948342859321	3.70509569419731e-06	cGMP-PKG signaling pathway: CACNA1C
hsa05205__145	1.79151943606797e-06	DOWN	-4.7769096626112	3.74862474428922e-06	Proteoglycans in cancer: PXN
hsa04022__50	1.8145760757324e-06	DOWN	-4.77433589662919	3.78003153691926e-06	cGMP-PKG signaling pathway: ATP2B1
hsa04742__48	1.8145760757324e-06	UP	4.77433589662919	3.78003153691926e-06	Taste transduction: GABBR1
hsa05164__34	1.8145760757324e-06	UP	4.77433589662919	3.78003153691926e-06	Influenza A: IL1B
hsa05221__29	1.8145760757324e-06	DOWN	-4.77433589662919	3.78003153691926e-06	Acute myeloid leukemia: RPS6KB1
hsa05205__91	1.83791770633017e-06	UP	4.77176213064718	3.82441569235259e-06	Proteoglycans in cancer: RAC1*
hsa04151__101	1.88546944242727e-06	UP	4.76661459868316	3.91902332115137e-06	PI3K-Akt signaling pathway: PKN3
hsa04919__49	1.95899451530736e-06	DOWN	-4.75889330073713	4.06734883343926e-06	Thyroid hormone signaling pathway: ACTB
hsa04670__86	2.00956777376233e-06	UP	4.75374576877311	4.16774596788015e-06	Leukocyte transendothelial migration: ACTB
hsa04115__50	2.03532238208714e-06	UP	4.7511720027911	4.21186206601512e-06	p53 signaling pathway: RCHY1
hsa05162__105	2.03532238208714e-06	UP	4.7511720027911	4.21186206601512e-06	Measles: GSK3B
hsa04062__22 41	2.06138501853036e-06	UP	4.74859823680909	4.26110280508091e-06	Chemokine signaling pathway: CRK PTK2B
hsa04270__28	2.22462235196292e-06	UP	4.73315564091703	4.59347846081135e-06	Vascular smooth muscle contraction: KCNMB2
hsa04917__48	2.31082702508219e-06	DOWN	-4.725434342971	4.76623927566348e-06	Prolactin signaling pathway: CCND2
hsa04970__27	2.4307677330487e-06	DOWN	-4.71513927904295	5.00812781841942e-06	Salivary secretion: PRKCA
hsa04062__25	2.4929572725963e-06	UP	4.70999174707893	5.1194171750912e-06	Chemokine signaling pathway: ROCK1
hsa04920__43	2.4929572725963e-06	DOWN	-4.70999174707893	5.1194171750912e-06	Adipocytokine signaling pathway: C00162
hsa05016__12	2.4929572725963e-06	DOWN	-4.70999174707893	5.1194171750912e-06	Huntington's disease: REST
hsa05012__70	2.62194938390536e-06	DOWN	-4.69969668315089	5.37843110519452e-06	Parkinson's disease: PRKACA
hsa05231__48	2.75733420525398e-06	UP	4.68940161922285	5.64997924936994e-06	Choline metabolism in cancer: WAS
hsa05212__8	2.79221434195683e-06	UP	4.68682785324084	5.71521868032341e-06	Pancreatic cancer: NFKB1
hsa04530__20 62	2.8632490614488e-06	DOWN	-4.68168032127682	5.8478749852851e-06	Tight junction: ACTB SHROOM1
hsa04912__20	2.8632490614488e-06	UP	4.68168032127682	5.8478749852851e-06	GnRH signaling pathway: PLA2G4B
hsa04912__43	3.08690824710833e-06	UP	4.66623772538476	6.29782909480625e-06	GnRH signaling pathway: PTK2B
hsa05212__19	3.12577792112491e-06	DOWN	-4.66366395940275	6.37021335552462e-06	Pancreatic cancer: MAPK8
hsa04152__49	3.24522404879175e-06	UP	4.65594266145672	6.60647452619686e-06	AMPK signaling pathway: GYS1
hsa04014__68	3.28600332663058e-06	UP	4.65336889547471	6.67502729809607e-06	Ras signaling pathway: RALGDS*
hsa04664__25	3.28600332663058e-06	UP	4.65336889547471	6.67502729809607e-06	Fc epsilon RI signaling pathway: MAPK14
hsa05152__68	3.32727380438871e-06	UP	4.6507951294927	6.75156315166996e-06	Tuberculosis: CD74
hsa04152__30	3.41131098088672e-06	UP	4.64564759752868	6.91462063979088e-06	AMPK signaling pathway: ACACA
hsa04728__24	3.49738143723737e-06	DOWN	-4.64050006556465	7.08144366440626e-06	Dopaminergic synapse: SLC6A3
hsa05152__77	3.54119374929916e-06	UP	4.63792629958264	7.1624360117687e-06	Tuberculosis: IL12A
hsa05161__66 67	3.5855320328959e-06	DOWN	-4.63535253360063	7.24431687076494e-06	Hepatitis B: NFKB1 NFKBIA
hsa04068__88	3.81532591538012e-06	DOWN	-4.62248370369058	7.70031943608941e-06	FoxO signaling pathway: FBXO32
hsa04612__17 28	3.86294868942111e-06	UP	4.61990993770857	7.78806929980929e-06	Antigen processing and presentation: CD4 HLA-DMA
hsa05032__37	3.95990916988067e-06	DOWN	-4.61476240574455	7.97499392305014e-06	Morphine addiction: KCNJ3
hsa04024__77	4.00925991997651e-06	UP	4.61218863976254	8.06573810453519e-06	cAMP signaling pathway: RHOA*
hsa05134__68	4.1097355772103e-06	UP	4.60704110779852	8.2590301065007e-06	Legionellosis: TNF
hsa04620__18	4.21262179503662e-06	UP	4.6018935758345	8.4567482402498e-06	Toll-like receptor signaling pathway: CXCL11
hsa04152__81	4.37159164979471e-06	DOWN	-4.59417227788847	8.76651089643998e-06	AMPK signaling pathway: LIPE
hsa04115__18	4.42584726483303e-06	UP	4.59159851190646	8.86584969149389e-06	p53 signaling pathway: CCNG1
hsa04933__23	4.53630018390143e-06	DOWN	-4.58645097994244	9.07743135841405e-06	AGE-RAGE signaling pathway in diabetic complications: F3
hsa05161__130	4.59251215603266e-06	UP	4.58387721396043	9.18013866083551e-06	Hepatitis B: FASLG*
hsa04370__38	4.70694438510736e-06	UP	4.57872968199641	9.38890498897742e-06	VEGF signaling pathway: BAD
hsa05205__238	4.70694438510736e-06	DOWN	-4.57872968199641	9.38890498897742e-06	Proteoglycans in cancer: ITGAV*
hsa04932__14	4.76517978494317e-06	DOWN	-4.5761559160144	9.49498707943608e-06	Non-alcoholic fatty liver disease (NAFLD): PKLR
hsa04724__52	4.82410493823089e-06	UP	4.57358215003239	9.60221735056764e-06	Glutamatergic synapse: CACNA1A
hsa04114__56	4.88372761961093e-06	DOWN	-4.57100838405038	9.69009946911188e-06	Oocyte meiosis: REC8
hsa04660__34	4.88372761961093e-06	DOWN	-4.57100838405038	9.69009946911188e-06	T cell receptor signaling pathway: FOS
hsa04742__18	4.88372761961093e-06	DOWN	-4.57100838405038	9.69009946911188e-06	Taste transduction: PDE1A
hsa04360__40 142	4.94405568646033e-06	DOWN	-4.56843461806837	9.76853904822182e-06	Axon guidance: UNC5D PTPN11
hsa05110__51	4.94405568646033e-06	UP	4.56843461806837	9.76853904822182e-06	Vibrio cholerae infection: PDIA4
hsa05169__31	4.94405568646033e-06	UP	4.56843461806837	9.76853904822182e-06	Epstein-Barr virus infection: MYC
hsa05205__256	4.94405568646033e-06	DOWN	-4.56843461806837	9.76853904822182e-06	Proteoglycans in cancer: ACTB
hsa05152__69	5.00509707971477e-06	UP	4.56586085208636	9.86839182873458e-06	Tuberculosis: HLA-DMA
hsa05169__83	5.00509707971477e-06	UP	4.56586085208636	9.86839182873458e-06	Epstein-Barr virus infection: GSK3B
hsa04724__65	5.12910740021982e-06	DOWN	-4.56071332012233	1.01022985377495e-05	Glutamatergic synapse: GRM3
hsa04330__19	5.52008912701365e-06	UP	4.54527072423027	1.08496312444128e-05	Notch signaling pathway: DTX2
hsa05200__191	5.52008912701365e-06	DOWN	-4.54527072423027	1.08496312444128e-05	Pathways in cancer: CCND1*
hsa04623__25	5.65655239850898e-06	DOWN	-4.54012319226625	1.11062298399147e-05	Cytosolic DNA-sensing pathway: NFKB1*
hsa04270__17	5.72598922745226e-06	DOWN	-4.53754942628424	1.1219117579127e-05	Vascular smooth muscle contraction: ITPR1
hsa04630__7	5.72598922745226e-06	DOWN	-4.53754942628424	1.1219117579127e-05	Jak-STAT signaling pathway: BCL2
hsa05212__10	5.79624150125187e-06	UP	4.53497566030223	1.13449351883878e-05	Pancreatic cancer: BCL2L1
hsa04520__43	5.93915900455524e-06	DOWN	-4.52982812833821	1.16006352448626e-05	Adherens junction: ACTB
hsa04152__38	5.93922890130805e-06	DOWN	-4.52982812833821	1.16006352448626e-05	AMPK signaling pathway: PFKL
hsa04670__55	6.01198252715726e-06	UP	4.5272543623562	1.17305453463432e-05	Leukocyte transendothelial migration: RAC2
hsa04530__14 20 43	6.16005661136697e-06	DOWN	-4.52210683039218	1.19945558266928e-05	Tight junction: CTNNA1 ACTB ACTN4
hsa05161__125	6.16005661136697e-06	UP	4.52210683039218	1.19945558266928e-05	Hepatitis B: CDKN1A
hsa05215__35	6.31161693648687e-06	DOWN	-4.51695929842816	1.22769443309098e-05	Prostate cancer: CASP9
hsa05200__184	6.6255098291502e-06	UP	4.50666423450012	1.2874180939993e-05	Pathways in cancer: GLI1
hsa04914__42	6.70628577677962e-06	DOWN	-4.50409046851811	1.30176766266208e-05	Progesterone-mediated oocyte maturation: ARAF
hsa04728__44	6.87067281153832e-06	DOWN	-4.49894293655409	1.33230074436331e-05	Dopaminergic synapse: FOS
hsa03320__64	6.95430486317849e-06	DOWN	-4.49636917057208	1.3471277152487e-05	PPAR signaling pathway: APOA5
hsa04151__35	7.03891009638492e-06	DOWN	-4.49379540459006	1.36211246870312e-05	PI3K-Akt signaling pathway: CCND1
hsa04380__16	7.21108324920025e-06	UP	4.48864787262604	1.39399438531351e-05	Osteoclast differentiation: NFKB1
hsa04261__20	7.47691443853194e-06	DOWN	-4.48092657468001	1.44389745426531e-05	Adrenergic signaling in cardiomyocytes: ATP1B4
hsa04270__46	7.56758862509837e-06	UP	4.478352808698	1.45841015657024e-05	Vascular smooth muscle contraction: ITPR1*
hsa05020__52	7.56758862509837e-06	DOWN	-4.478352808698	1.45841015657024e-05	Prion diseases: FYN
hsa04740__42	7.94091035414661e-06	DOWN	-4.46805774476996	1.52878796674605e-05	Olfactory transduction: PDE2A
hsa04010__119	8.03695575830804e-06	DOWN	-4.46548397878795	1.54569497132659e-05	MAPK signaling pathway: NFATC3
hsa04068__55	8.5340767609624e-06	DOWN	-4.4526151488779	1.63962476828715e-05	FoxO signaling pathway: ATM
hsa04930__9	8.6368685216336e-06	UP	4.45004138289589	1.6576788510878e-05	Type II diabetes mellitus: C00238
hsa04530__11 13	8.9527978666498e-06	DOWN	-4.44232008494986	1.71481214999337e-05	Tight junction: TJP1 EPB41
hsa04921__76	8.9527978666498e-06	UP	4.44232008494986	1.71481214999337e-05	Oxytocin signaling pathway: CDKN1A
hsa05161__69	9.27964676319545e-06	UP	4.43459878700383	1.77560654460736e-05	Hepatitis B: SMAD4
hsa04115__24	9.50384640674959e-06	UP	4.42945125503981	1.81665588995753e-05	p53 signaling pathway: SERPINB5
hsa04620__19	9.61787763874669e-06	UP	4.4268774890578	1.83472000844721e-05	Toll-like receptor signaling pathway: CXCL10
hsa05223__37	9.61787763874669e-06	DOWN	-4.4268774890578	1.83472000844721e-05	Non-small cell lung cancer: CCND1*
hsa05219__27	9.96786598585487e-06	DOWN	-4.41915619111176	1.89955579994131e-05	Bladder cancer: RPS6KA5
hsa04920__40	1.00872081078723e-05	DOWN	-4.41658242512975	1.92035096602756e-05	Adipocytokine signaling pathway: PPARGC1A
hsa05200__196	1.04534773262967e-05	UP	4.40886112718372	1.9880651716712e-05	Pathways in cancer: TRAF1
hsa05200__48	1.0961631275247e-05	DOWN	-4.39856606325568	2.08259910679364e-05	Pathways in cancer: MTOR
hsa05152__112	1.13581344116207e-05	UP	4.39084476530965	2.15575096559952e-05	Tuberculosis: IFNGR1
hsa04012__48	1.14933179301246e-05	DOWN	-4.38827099932764	2.17920730481373e-05	ErbB signaling pathway: CAMK2A
hsa04014__103	1.21925935497197e-05	DOWN	-4.37540216941759	2.30946404031485e-05	Ras signaling pathway: KSR2
hsa05166__32	1.24835195490276e-05	UP	4.37025463745357	2.36218864376866e-05	HTLV-I infection: STAT5A
hsa05200__75	1.29323595637428e-05	UP	4.36253333950754	2.44465831189867e-05	Pathways in cancer: MAPK8
hsa04921__57	1.30853645672687e-05	DOWN	-4.35995957352553	2.46861446002991e-05	Oxytocin signaling pathway: FOS
hsa05215__9	1.30853645672687e-05	DOWN	-4.35995957352553	2.46861446002991e-05	Prostate cancer: CDKN1B
hsa04668__111	1.32400956748988e-05	UP	4.35738580754352	2.49529987694432e-05	TNF signaling pathway: BAG4
hsa05145__23	1.40402945412814e-05	UP	4.34451697763347	2.64345826082843e-05	Toxoplasmosis: CIITA
hsa04670__14	1.43731164674061e-05	UP	4.33936944566944	2.70341199622184e-05	Leukocyte transendothelial migration: SIPA1
hsa04919__42	1.45423358382902e-05	DOWN	-4.33679567968743	2.73250490401472e-05	Thyroid hormone signaling pathway: SLC2A1
hsa04022__66	1.47134540312504e-05	DOWN	-4.33422191370542	2.7618961163556e-05	cGMP-PKG signaling pathway: PDE3A
hsa04913__12	1.48864912068503e-05	DOWN	-4.33164814772341	2.79158852072573e-05	Ovarian steroidogenesis: HSD3B1
hsa04390__94	1.50614677261751e-05	DOWN	-4.3290743817414	2.82158503065633e-05	Hippo signaling pathway: GLI2
hsa04261__15 16	1.57811815842225e-05	DOWN	-4.31877931781336	2.95053136286111e-05	Adrenergic signaling in cardiomyocytes: ACTC1 TPM1
hsa04920__2	1.57811815842225e-05	DOWN	-4.31877931781336	2.95053136286111e-05	Adipocytokine signaling pathway: C00638
hsa04730__7	1.61532190140514e-05	DOWN	-4.31363178584934	3.01708732876764e-05	Long-term depression: GNA13
hsa04930__3	1.65336072296597e-05	DOWN	-4.30848425388532	3.08506931326024e-05	Type II diabetes mellitus: SLC2A4
hsa04014__33	1.69225233682821e-05	UP	4.3033367219213	3.1545060921629e-05	Ras signaling pathway: BCL2L1
hsa05221__21	1.73201480814035e-05	DOWN	-4.29818918995728	3.22542698166077e-05	Acute myeloid leukemia: PIM1
hsa04020__22	1.7522035240948e-05	DOWN	-4.29561542397527	3.2566143277718e-05	Calcium signaling pathway: C00575
hsa05321__138	1.75222835837003e-05	UP	4.29561542397527	3.2566143277718e-05	Inflammatory bowel disease (IBD): IFNG**
hsa04630__27	1.8783107480349e-05	DOWN	-4.28017282808321	3.48749594422685e-05	Jak-STAT signaling pathway: PIM1
hsa04012__37 7	1.90014723331742e-05	UP	4.2775990621012	3.52455740513666e-05	ErbB signaling pathway: ERBB3 ERBB3
hsa05200__198	1.92222538324482e-05	UP	4.27502529611919	3.56199358492802e-05	Pathways in cancer: BCL2L1*
hsa04064__137	1.96711680827004e-05	UP	4.26987776415517	3.64158865294523e-05	NF-kappa B signaling pathway: ICAM1
hsa04713__14	2.01300553383955e-05	UP	4.26473023219114	3.7228714548076e-05	Circadian entrainment: PRKCA
hsa04390__59	2.03633040371736e-05	DOWN	-4.26215646620913	3.7586098512622e-05	Hippo signaling pathway: SERPINE1
hsa05164__68	2.03633040371736e-05	UP	4.26215646620913	3.7586098512622e-05	Influenza A: EIF2S1
hsa04062__44	2.05991247290796e-05	UP	4.25958270022712	3.79840582590193e-05	Chemokine signaling pathway: MAPK1
hsa04610__45	2.08375441956782e-05	UP	4.25700893424511	3.8386025042823e-05	Complement and coagulation cascades: C4A
hsa04115__2	2.10785894790507e-05	UP	4.2544351682631	3.87540798739102e-05	p53 signaling pathway: IGFBP3
hsa05200__200	2.10785894790507e-05	DOWN	-4.2544351682631	3.87540798739102e-05	Pathways in cancer: FIGF
hsa04380__38	2.13222878841248e-05	UP	4.25186140228109	3.91638112749466e-05	Osteoclast differentiation: FOS
hsa04530__11 43	2.25815511042188e-05	DOWN	-4.23899257237104	4.14362641844014e-05	Tight junction: TJP1 ACTN4
hsa04210__86	2.28417566606575e-05	DOWN	-4.23641880638903	4.1872839771098e-05	Apoptosis: BCL2L11
hsa04014__24	2.31048140326376e-05	UP	4.23384504040702	4.2313787102657e-05	Ras signaling pathway: PLD1
hsa04014__30	2.33707527139932e-05	DOWN	-4.23127127442501	4.27591473705874e-05	Ras signaling pathway: C01245
hsa04950__1	2.44636689533944e-05	UP	4.22097621049697	4.47152081356305e-05	Maturity onset diabetes of the young: HNF1B
hsa04152__94	2.47447181141911e-05	DOWN	-4.21840244451496	4.5141092559772e-05	AMPK signaling pathway: MLYCD
hsa05162__58	2.47447181141911e-05	UP	4.21840244451496	4.5141092559772e-05	Measles: STAT3
hsa04270__65	2.56056236775308e-05	UP	4.21068114656893	4.66210919477523e-05	Vascular smooth muscle contraction: NPR2
hsa05220__25	2.56056236775308e-05	UP	4.21068114656893	4.66210919477523e-05	Chronic myeloid leukemia: BCL2L1*
hsa05014__31 34	2.77265389361451e-05	UP	4.19266478469485	5.0433849623443e-05	Amyotrophic lateral sclerosis (ALS): NEFL PRPH
hsa04115__40	2.96764158868906e-05	UP	4.17722218880279	5.39284191987113e-05	p53 signaling pathway: PIDD1
hsa05032__38	3.03548459707025e-05	UP	4.17207465683877	5.51079764047827e-05	Morphine addiction: CACNA1A
hsa05215__13	3.10479988949195e-05	UP	4.16692712487475	5.63119593856697e-05	Prostate cancer: BCL2
hsa04340__50	3.14001901815586e-05	UP	4.16435335889274	5.68958122961896e-05	Hedgehog signaling pathway: BCL2
hsa05231__17	3.24796819401686e-05	UP	4.15663206094671	5.87951082520008e-05	Choline metabolism in cancer: SLC44A3
hsa04066__47	3.39739401056989e-05	DOWN	-4.14633699701867	6.14408406723853e-05	HIF-1 signaling pathway: PGK1
hsa04540__16 17	3.63383036261455e-05	DOWN	-4.13089440112661	6.55275168076078e-05	Gap junction: GJA1 GJA1**
hsa05014__54	3.63383036261455e-05	DOWN	-4.13089440112661	6.55275168076078e-05	Amyotrophic lateral sclerosis (ALS): PPP3CA
hsa05205__144	3.63383036261455e-05	DOWN	-4.13089440112661	6.55275168076078e-05	Proteoglycans in cancer: NUDT16L1
hsa04919__104	3.67472476104828e-05	DOWN	-4.1283206351446	6.60747160383705e-05	Thyroid hormone signaling pathway: MYC
hsa04933__56	3.67472476104828e-05	UP	4.1283206351446	6.60747160383705e-05	AGE-RAGE signaling pathway in diabetic complications: NFATC1
hsa05200__193	3.67472476104828e-05	DOWN	-4.1283206351446	6.60747160383705e-05	Pathways in cancer: NOS2
hsa04664__3 4 5	3.88582285553783e-05	UP	4.11545180523454	6.97372013680471e-05	Fc epsilon RI signaling pathway: FCER1G MS4A2 FCER1A
hsa04340__49	3.88583554190236e-05	UP	4.11545180523454	6.97372013680471e-05	Hedgehog signaling pathway: CCND1
hsa04621__21 30	4.06296074611716e-05	UP	4.1051567413065	7.28464049804784e-05	NOD-like receptor signaling pathway: NLRP3 PYCARD
hsa05140__21	4.15437067740349e-05	UP	4.10000920934248	7.44143231920034e-05	Leishmaniasis: NFKB1
hsa04152__24	4.29515226709521e-05	DOWN	-4.09228791139645	7.68627724749706e-05	AMPK signaling pathway: SIRT1
hsa04211__50	4.44045180075184e-05	DOWN	-4.08456661345042	7.93118719925162e-05	Longevity regulating pathway - mammal: PPARGC1A*
hsa04810__30	4.44045180075184e-05	DOWN	-4.08456661345042	7.93118719925162e-05	Regulation of actin cytoskeleton: VCL*
hsa04730__8	4.4899123724568e-05	DOWN	-4.08199284746841	8.01191391058531e-05	Long-term depression: GNA13*
hsa03320__36	4.69302879607934e-05	DOWN	-4.07169778354037	8.36641471331412e-05	PPAR signaling pathway: SLC27A4
hsa04390__17 51	4.79782516986459e-05	DOWN	-4.06655025157635	8.53703929372686e-05	Hippo signaling pathway: YWHAQ YAP1
hsa04630__31	4.79782516986459e-05	DOWN	-4.06655025157635	8.53703929372686e-05	Jak-STAT signaling pathway: BCL2L1
hsa04923__26 27	4.95912551028249e-05	UP	4.05882895363032	8.81570182953718e-05	Regulation of lipolysis in adipocytes: PNPLA2 ABHD5
hsa04072__3	5.18235461339422e-05	DOWN	-4.04853388970228	9.1951315567212e-05	Phospholipase D signaling pathway: MAPK1
hsa05142__18	5.18235461339422e-05	UP	4.04853388970228	9.1951315567212e-05	Chagas disease (American trypanosomiasis): FOS
hsa04213__13	5.29747490862017e-05	DOWN	-4.04338635773825	9.39052391820501e-05	Longevity regulating pathway - multiple species: RPS6KB1*
hsa04973__36	5.47470843261811e-05	UP	4.03566505979222	9.69554867567336e-05	Carbohydrate digestion and absorption: SLC2A2
hsa04950__21	5.53502433696994e-05	DOWN	-4.03309129381021	9.79313627981782e-05	Maturity onset diabetes of the young: PKLR
hsa05162__44	5.65754975553088e-05	UP	4.02794376184619	0.000100005042244991	Measles: PRKCQ
hsa04020__18	5.84609205275142e-05	UP	4.02022246390016	0.000102951679108754	Calcium signaling pathway: C00002
hsa04020__17	5.84609205275142e-05	UP	4.02022246390016	0.000102951679108754	Calcium signaling pathway: C00004
hsa04020__15	5.84609205275142e-05	UP	4.02022246390016	0.000102951679108754	Calcium signaling pathway: C13051
hsa04550__22	5.84616506700586e-05	UP	4.02022246390016	0.000102951679108754	Signaling pathways regulating pluripotency of stem cells: SMAD2
hsa05210__23	6.10692968167566e-05	DOWN	-4.00992739997212	0.000107443079324612	Colorectal cancer: CCND1
hsa04917__31	6.17382084588259e-05	DOWN	-4.00735363399011	0.000108518328993577	Prolactin signaling pathway: GALT
hsa05134__9	6.58996407338269e-05	UP	3.99191103809805	0.000115724696204543	Legionellosis: CASP7
hsa05164__20	6.73448076068737e-05	DOWN	-3.98676350613403	0.000118152094765001	Influenza A: ATF2
hsa04151__105 62	6.95689033328577e-05	DOWN	-3.979042208188	0.000121940269927649	PI3K-Akt signaling pathway: CCND1 CDK2
hsa04530__6 11 45	7.10900484588424e-05	DOWN	-3.97389467622398	0.000124490401728019	Tight junction: CLDN24 TJP1 TJP2
hsa05032__30	7.34304328123518e-05	UP	3.96617337827794	0.000128469071931479	Morphine addiction: ADORA1
hsa05160__37	7.58401124675667e-05	DOWN	-3.95845208033191	0.000132561461699124	Hepatitis C: STAT3
hsa04710__11	7.66655498985361e-05	UP	3.9558783143499	0.000133755402283518	Circadian rhythm: CRY1
hsa04726__71	7.66655498985361e-05	UP	3.9558783143499	0.000133755402283518	Serotonergic synapse: CACNA1A
hsa04666__40	7.83329667301688e-05	UP	3.95073078238588	0.000136537703604812	Fc gamma R-mediated phagocytosis: PLA2G6
hsa04152__58	7.91794763007946e-05	UP	3.94815701640387	0.000137885297469132	AMPK signaling pathway: SCD
hsa04210__62	8.00346288063495e-05	DOWN	-3.94558325042186	0.000139245432895491	Apoptosis: TP53AIP1
hsa04726__72	8.08985067693584e-05	DOWN	-3.94300948443985	0.000140618218519542	Serotonergic synapse: KCNJ3
hsa04620__86	8.17711934381674e-05	UP	3.94043571845784	0.000142003763835782	Toll-like receptor signaling pathway: IL12A
hsa04722__70	8.44429491709944e-05	UP	3.93271442051181	0.000146372971856364	Neurotrophin signaling pathway: ZNF274
hsa04724__67	8.44429491709944e-05	UP	3.93271442051181	0.000146372971856364	Glutamatergic synapse: PLD1
hsa04919__101	8.53517178646242e-05	DOWN	-3.9301406545298	0.000147811869002423	Thyroid hormone signaling pathway: NOTCH1
hsa05221__41	8.71970510884882e-05	DOWN	-3.92499312256578	0.000150868562610745	Acute myeloid leukemia: MAPK1
hsa05166__89 90	9.00358679324025e-05	UP	3.91727182461975	0.000155636978698238	HTLV-I infection: CHUK IKBKG
hsa04152__87	9.10013841539816e-05	DOWN	-3.91469805863774	0.0001571613978174	AMPK signaling pathway: CD36
hsa04261__36	9.19766743873449e-05	UP	3.91212429265573	0.000158699881702315	Adrenergic signaling in cardiomyocytes: MAPK1
hsa04742__55	9.29510967077275e-05	UP	3.90955052667372	0.00016023404652644	Taste transduction: P2RX3
hsa04380__72	9.49621173549786e-05	UP	3.9044029947097	0.000163102210703843	Osteoclast differentiation: MAPK1
hsa04670__35	9.49621173549786e-05	DOWN	-3.9044029947097	0.000163102210703843	Leukocyte transendothelial migration: PTK2
hsa05031__11	9.49621173549786e-05	UP	3.9044029947097	0.000163102210703843	Amphetamine addiction: GRIN3A
hsa05031__54	9.49621173549786e-05	UP	3.9044029947097	0.000163102210703843	Amphetamine addiction: GRIN3A*
hsa04064__93	9.59774358751857e-05	DOWN	-3.90182922872769	0.000164695526949291	NF-kappa B signaling pathway: PLAU
hsa04014__97	9.80389020034502e-05	UP	3.89668169676366	0.000167773312262735	Ras signaling pathway: PAK4
hsa04150__31	9.80389020034502e-05	DOWN	-3.89668169676366	0.000167773312262735	mTOR signaling pathway: EIF4E
hsa04724__5 71	9.80389020034502e-05	UP	3.89668169676366	0.000167773312262735	Glutamatergic synapse: GRIN3A DLG4
hsa04340__26	9.90852434430305e-05	DOWN	-3.89410793078165	0.000169409620044999	Hedgehog signaling pathway: PTCH1**
hsa04610__57	0.000100142121085894	UP	3.89153416479964	0.000171060950473086	Complement and coagulation cascades: PLAUR
hsa04610__46	0.00010337696574975	UP	3.88381286685361	0.000176266169368221	Complement and coagulation cascades: C2
hsa04722__50	0.00010337696574975	UP	3.88381286685361	0.000176266169368221	Neurotrophin signaling pathway: RHOA
hsa04727__8	0.000105588048229722	DOWN	-3.87866533488959	0.000179873021417632	GABAergic synapse: ADCY1
hsa04151__96	0.000107843704796482	UP	3.87351780292557	0.000183549204087491	PI3K-Akt signaling pathway: BCL2
hsa04530__5 11 31	0.00011014477306441	DOWN	-3.86837027096155	0.000187295953473328	Tight junction: IGSF5 TJP1 MLLT4
hsa04210__107	0.000111312602281121	DOWN	-3.86579650497954	0.000188769295745691	Apoptosis: MCL1
hsa04360__81	0.000111312602281121	UP	3.86579650497954	0.000188769295745691	Axon guidance: FYN*
hsa04922__36	0.000111312602281121	UP	3.86579650497954	0.000188769295745691	Glucagon signaling pathway: GYS1
hsa04919__27	0.000113683390259287	DOWN	-3.86064897301552	0.000192615951575473	Thyroid hormone signaling pathway: GATA4
hsa04064__134	0.000117329042039865	DOWN	-3.85292767506949	0.000198613756750366	NF-kappa B signaling pathway: CCL21
hsa04024__25	0.000118568563416599	DOWN	-3.85035390908748	0.000200351016780386	cAMP signaling pathway: CFTR
hsa04066__62	0.000118568563416599	UP	3.85035390908748	0.000200351016780386	HIF-1 signaling pathway: NPPA
hsa04310__36	0.000119820425251284	UP	3.84778014310547	0.000202284437598528	Wnt signaling pathway: MYC
hsa04210__52	0.000122361629204657	DOWN	-3.84263261114145	0.00020620403701843	Apoptosis: PARP2
hsa04310__31	0.000122361629204657	UP	3.84263261114145	0.00020620403701843	Wnt signaling pathway: MMP7
hsa04010__62	0.000123651203218764	UP	3.84005884515944	0.000208004127885459	MAPK signaling pathway: MEF2C
hsa04726__38	0.000123651203218764	DOWN	-3.84005884515944	0.000208004127885459	Serotonergic synapse: PLA2G4B
hsa04919__31	0.000124953581496456	DOWN	-3.83748507917743	0.000210006958525797	Thyroid hormone signaling pathway: ATP2A2
hsa04151__103	0.000126268882459159	UP	3.83491131319542	0.000212027908972975	PI3K-Akt signaling pathway: BCL2*
hsa04068__42	0.000127597225531262	DOWN	-3.83233754721341	0.000214067131047537	FoxO signaling pathway: CDKN2D
hsa04727__35	0.000128938731147686	DOWN	-3.8297637812314	0.000216124777722126	GABAergic synapse: PRKACA
hsa05014__33 34	0.000130293520761494	UP	3.82719001524939	0.000218201003129098	Amyotrophic lateral sclerosis (ALS): NEFH PRPH
hsa04066__49	0.000134438823551147	DOWN	-3.81946871730335	0.000224942608595374	HIF-1 signaling pathway: EPO
hsa04933__78	0.000137271051887541	UP	3.81432118533933	0.00022947714101129	AGE-RAGE signaling pathway in diabetic complications: TGFB1
hsa04930__13	0.000138708153987117	UP	3.81174741935732	0.000231673441192705	Type II diabetes mellitus: C00162
hsa04152__53	0.000141624978043319	DOWN	-3.8065998873933	0.000236335109896444	AMPK signaling pathway: G6PC
hsa04066__54	0.000146108728322334	DOWN	-3.79887858944727	0.000243600976501921	HIF-1 signaling pathway: SERPINE1
hsa05014__32 34	0.000153879950896021	UP	3.78600975953722	0.000256103124653342	Amyotrophic lateral sclerosis (ALS): NEFM PRPH
hsa05210__9 11	0.000153879950896021	DOWN	-3.78600975953722	0.000256103124653342	Colorectal cancer: SMAD2 SMAD4
hsa04015__95	0.000155480175235436	DOWN	-3.78343599355521	0.000258537388732199	Rap1 signaling pathway: THBS1
hsa04510__20 69	0.000158727725900066	UP	3.77828846159119	0.000263704152932116	Focal adhesion: VASP ACTB
hsa04066__37	0.000170603916744973	DOWN	-3.76027209971712	0.000283184416575799	HIF-1 signaling pathway: PDHA1
hsa04012__47	0.000174147655363838	DOWN	-3.7551245677531	0.000288302594210265	ErbB signaling pathway: PRKCA
hsa04014__54	0.000174147655363838	UP	3.7551245677531	0.000288302594210265	Ras signaling pathway: RHOA
hsa04064__94	0.000174147655363838	UP	3.7551245677531	0.000288302594210265	NF-kappa B signaling pathway: BCL2L1*
hsa04810__23	0.000177760535347459	DOWN	-3.74997703578908	0.000294024688307988	Regulation of actin cytoskeleton: GSN
hsa04115__43 57	0.000189026640963691	UP	3.73453443989701	0.00031210989312019	p53 signaling pathway: CDK1 CCNB3
hsa05210__16	0.000189026640963691	UP	3.73453443989701	0.00031210989312019	Colorectal cancer: MAPK8
hsa04620__21	0.000194908160274506	UP	3.72681314195098	0.000320693899435898	Toll-like receptor signaling pathway: IFNA1
hsa04723__42	0.000194908160274506	UP	3.72681314195098	0.000320693899435898	Retrograde endocannabinoid signaling: KCNJ3
hsa04723__50	0.000194908160274506	UP	3.72681314195098	0.000320693899435898	Retrograde endocannabinoid signaling: KCNJ3*
hsa05134__59	0.000194908160274506	UP	3.72681314195098	0.000320693899435898	Legionellosis: HSPA1A
hsa04062__35 36 37	0.000211444004234366	UP	3.7062230140949	0.000346989767647487	Chemokine signaling pathway: PARD3 PRKCZ TIAM1
hsa04660__56	0.000211444004234366	UP	3.7062230140949	0.000346989767647487	T cell receptor signaling pathway: CD3E
hsa05132__6	0.000211444004234366	DOWN	-3.7062230140949	0.000346989767647487	Salmonella infection: NFKB1
hsa04360__29	0.000215779135040075	UP	3.70107548213088	0.00035379493432836	Axon guidance: RASA1
hsa05205__150	0.000220197618471395	DOWN	-3.69592795016686	0.000360724782134047	Proteoglycans in cancer: PRKCA
hsa04950__7	0.000222438580026429	DOWN	-3.69335418418485	0.000364078477238379	Maturity onset diabetes of the young: FOXA3
hsa04213__2	0.000224700937843595	DOWN	-3.69078041820284	0.000367461324811241	Longevity regulating pathway - multiple species: RPS6KB1
hsa05200__49	0.000226984881080716	DOWN	-3.68820665222083	0.000370873557870143	Pathways in cancer: CASP9
hsa05133__46	0.000233966901952187	DOWN	-3.6804853542748	0.000381619905180265	Pertussis: CFL1
hsa04932__97	0.000233968137715628	UP	3.6804853542748	0.000381619905180265	Non-alcoholic fatty liver disease (NAFLD): TNF*
hsa05161__31	0.000236340344719881	DOWN	-3.67791158829279	0.00038482106388965	Hepatitis B: ELK1
hsa05166__26	0.000236340344719881	DOWN	-3.67791158829279	0.00038482106388965	HTLV-I infection: NFATC1
hsa04068__48	0.000253588534034902	UP	3.65989522641871	0.000412191051428703	FoxO signaling pathway: FASLG
hsa05321__123	0.000253588534034902	DOWN	-3.65989522641871	0.000412191051428703	Inflammatory bowel disease (IBD): IL5*
hsa05205__422	0.000263967643233985	DOWN	-3.64960016249067	0.000428690753359255	Proteoglycans in cancer: CD63
hsa04620__77	0.000266623950047396	UP	3.64702639650866	0.000432257465176062	Toll-like receptor signaling pathway: CXCL9
hsa04726__39	0.000266623950047396	DOWN	-3.64702639650866	0.000432257465176062	Serotonergic synapse: CACNA1C
hsa04380__32	0.000294600905276943	UP	3.62128873668856	0.000477202673289116	Osteoclast differentiation: AKT3
hsa04670__10	0.000303515927968527	UP	3.61356743874253	0.000491220007452939	Leukocyte transendothelial migration: BCAR1
hsa04062__8 41	0.000306543314710259	UP	3.61099367276052	0.00049569267499189	Chemokine signaling pathway: PXN PTK2B
hsa04390__77	0.000325309616811685	DOWN	-3.59555107686845	0.000525586216671673	Hippo signaling pathway: CCND1
hsa04210__102	0.000328539979518867	UP	3.59297731088644	0.000530349331199271	Apoptosis: PIDD1
hsa04961__13	0.000331800342684626	DOWN	-3.59040354490443	0.000535152655711942	Endocrine and other factor-regulated calcium reabsorption: ATP2B1
hsa04630__28	0.000355484721540176	DOWN	-3.57238718303036	0.000572860884883353	Jak-STAT signaling pathway: CCND1
hsa04972__51	0.000358994501831251	DOWN	-3.56981341704835	0.000578021138766856	Pancreatic secretion: CLCA1
hsa04151__5	0.000362536666354426	DOWN	-3.56723965106634	0.000583224654178054	PI3K-Akt signaling pathway: EIF4B
hsa04750__90	0.0003697192506948	UP	3.56209211910232	0.000594270720321239	Inflammatory mediator regulation of TRP channels: C01245**
hsa04261__23	0.000380742955650695	DOWN	-3.55437082115629	0.000611466678348424	Adrenergic signaling in cardiomyocytes: SLC9A1
hsa05200__210	0.000392073274690897	DOWN	-3.54664952321026	0.000629125263146196	Pathways in cancer: MMP1
hsa05161__126	0.000395919533044869	UP	3.54407575722825	0.000634754951016474	Hepatitis B: MYC*
hsa04014__26	0.000399801023136261	DOWN	-3.54150199124624	0.000639885964627797	Ras signaling pathway: PRKCA
hsa04062__42	0.000399801023136261	UP	3.54150199124624	0.000639885964627797	Chemokine signaling pathway: PAK1
hsa04390__52	0.000419747415624919	UP	3.52863316133618	0.000671238633156785	Hippo signaling pathway: ITGB2
hsa04115__9	0.0004806518045558	DOWN	-3.49260043758804	0.00076798022173499	p53 signaling pathway: RPRM
hsa05321__19	0.000485303324876823	UP	3.49002667160603	0.000774753566222217	Inflammatory bowel disease (IBD): TNF
hsa04014__43	0.000504332439337552	DOWN	-3.47973160767799	0.000804448772084261	Ras signaling pathway: ELK1
hsa05134__69	0.000529097170541035	UP	3.46686277776794	0.000843234591557765	Legionellosis: IL1B*
hsa04611__43	0.00053418416905231	DOWN	-3.46428901178593	0.000850620384448551	Platelet activation: MYL12B
hsa04310__32	0.000539316710396978	UP	3.46171524580392	0.000858066129412297	Wnt signaling pathway: PPARD
hsa04024__60	0.000554991339415401	UP	3.45399394785789	0.000880024241992859	cAMP signaling pathway: PDE3A
hsa04151__63	0.000554991339415401	DOWN	-3.45399394785789	0.000880024241992859	PI3K-Akt signaling pathway: CASP9
hsa05152__6	0.000554991339415401	UP	3.45399394785789	0.000880024241992859	Tuberculosis: IL10
hsa05212__12	0.000554991339415401	DOWN	-3.45399394785789	0.000880024241992859	Pancreatic cancer: CASP9
hsa04014__64	0.000560309813793985	UP	3.45142018187587	0.000886960522425356	Ras signaling pathway: PIK3R5*
hsa04919__99	0.000560309813793985	DOWN	-3.45142018187587	0.000886960522425356	Thyroid hormone signaling pathway: WNT4
hsa04024__107 64	0.000565675725631848	UP	3.44884641589386	0.000894700916214009	cAMP signaling pathway: NFKBIA NFKB1
hsa04924__30	0.000593230499358523	DOWN	-3.43597758598381	0.00093749378325876	Renin secretion: PDE3A
hsa04932__138	0.000604598243255543	UP	3.43083005401979	0.000954655545442996	Non-alcoholic fatty liver disease (NAFLD): CEBPA
hsa04910__57	0.000616168451112904	DOWN	-3.42568252205577	0.000972107909018596	Insulin signaling pathway: GCK
hsa04015__96	0.000633910601289983	DOWN	-3.41796122410974	0.000999260083744864	Rap1 signaling pathway: PLCE1
hsa04724__33 70 69	0.000646001484223613	UP	3.41281369214572	0.00101661372601019	Glutamatergic synapse: ITPR1 HOMER3 HOMER3
hsa04933__65	0.000646001484223613	UP	3.41281369214572	0.00101661372601019	AGE-RAGE signaling pathway in diabetic complications: COL1A1
hsa05200__186	0.000670829319459372	UP	3.40251862821768	0.00105480191737587	Pathways in cancer: PTCH1*
hsa05161__48	0.000690029264347932	UP	3.39479733027165	0.00108317877001651	Hepatitis B: STAT1
hsa05169__103	0.000690029264347932	UP	3.39479733027165	0.00108317877001651	Epstein-Barr virus infection: NFKB1*
hsa04520__10	0.00072316798024438	UP	3.3819285003616	0.00113425094731151	Adherens junction: NLK
hsa05222__34	0.000736832758418631	DOWN	-3.37678096839757	0.00115471956052428	Small cell lung cancer: CCND1
hsa05211__42	0.000743754724598645	DOWN	-3.37420720241556	0.00116459593960071	Renal cell carcinoma: SLC2A1*
hsa04660__40 41	0.000750737042659977	UP	3.37163343643355	0.00117455029405337	T cell receptor signaling pathway: LAT GRAP2
hsa05164__41 42	0.000757780192148345	UP	3.36905967045154	0.00118458317890744	Influenza A: STAT1 IRF9
hsa05166__99	0.000764884655977945	UP	3.36648590446953	0.00119469515260396	HTLV-I infection: JUN
hsa04660__41 46	0.000772050920451132	UP	3.36391213848752	0.00120488677701634	T cell receptor signaling pathway: GRAP2 LCP2
hsa04360__114	0.000779279475278205	DOWN	-3.36133837250551	0.00121515861746701	Axon guidance: RAF1
hsa04064__116	0.000823986759871647	UP	3.34589577661345	0.0012838069003307	NF-kappa B signaling pathway: GADD45B
hsa05161__78	0.000839410272296072	UP	3.34074824464943	0.00130675385388924	Hepatitis B: TNF
hsa05164__47	0.000863048270275693	UP	3.3330269467034	0.00134132977654924	Influenza A: CIITA
hsa05200__205	0.000863048270275693	DOWN	-3.3330269467034	0.00134132977654924	Pathways in cancer: SLC2A1
hsa04910__12	0.000871063774597196	DOWN	-3.33045318072139	0.00135266845658523	Insulin signaling pathway: FASN
hsa04931__140	0.000879148254776682	UP	3.32787941473938	0.00136409543412501	Insulin resistance: G00369
hsa05223__8	0.000895526304599428	DOWN	-3.32273188277536	0.00138836132536495	Non-small cell lung cancer: CASP9
hsa04510__42	0.000903820964494682	DOWN	-3.32015811679335	0.0014000656160639	Focal adhesion: BIRC2
hsa04662__29	0.000929134104518179	UP	3.31243681884732	0.00143809141877237	B cell receptor signaling pathway: RAC1
hsa04024__43	0.000937716732418386	DOWN	-3.30986305286531	0.00145018085614333	cAMP signaling pathway: MAPK8
hsa04728__68	0.000990773926521688	DOWN	-3.29442045697324	0.00153097385520909	Dopaminergic synapse: CACNA1C
hsa05200__52	0.00100906842200108	DOWN	-3.28927292500922	0.00155796184465081	Pathways in cancer: CDKN1B
hsa05142__29	0.00101833247035059	DOWN	-3.28669915902721	0.00157097431181343	Chagas disease (American trypanosomiasis): NOS2
hsa05321__122	0.00103709717604202	DOWN	-3.28155162706319	0.00159861000310333	Inflammatory bowel disease (IBD): IL4**
hsa05133__24	0.00104659904869118	DOWN	-3.27897786108118	0.00161193410859895	Pertussis: NFKB1
hsa04932__96	0.00107559012393082	DOWN	-3.27125656313515	0.00165387384849919	Non-alcoholic fatty liver disease (NAFLD): IL6*
hsa05205__318	0.00107559012393082	DOWN	-3.27125656313515	0.00165387384849919	Proteoglycans in cancer: HSPB2
hsa04360__101 103	0.00109532828650814	UP	3.26610903117113	0.00168147209995816	Axon guidance: DPYSL2 DPYSL5
hsa04724__36	0.00109532828650814	UP	3.26610903117113	0.00168147209995816	Glutamatergic synapse: TRPC1
hsa05223__14	0.00110532249291135	UP	3.26353526518912	0.00169542935851463	Non-small cell lung cancer: CCND1
hsa04310__33	0.00111540096653243	UP	3.26096149920711	0.00170949299846203	Wnt signaling pathway: CCND1
hsa05221__27	0.00113581329244869	DOWN	-3.25581396724309	0.0017379423261491	Acute myeloid leukemia: PIM2
hsa05221__6	0.00113581329244869	UP	3.25581396724309	0.0017379423261491	Acute myeloid leukemia: CEBPA
hsa05205__45 46	0.00115657046132805	UP	3.25066643527907	0.00176826354502475	Proteoglycans in cancer: PAK1 FLNA
hsa04012__65	0.00119914046385874	UP	3.24037137135103	0.00182888387304429	ErbB signaling pathway: MYC
hsa04610__7	0.00119914046385874	DOWN	-3.24037137135103	0.00182888387304429	Complement and coagulation cascades: C00290
hsa04611__7	0.00119914046385874	UP	3.24037137135103	0.00182888387304429	Platelet activation: ITPR1
hsa04725__25	0.00122096404150202	UP	3.23522383938701	0.00185915027065015	Cholinergic synapse: CACNA1A
hsa05162__27 28	0.00122096404150202	UP	3.23522383938701	0.00185915027065015	Measles: STAT1 IRF9
hsa05166__33	0.00122786922845112	UP	3.02160126288015	0.00186815083421834	HTLV-I infection: HLA-A
hsa05220__22	0.00124315395160538	DOWN	-3.23007630742298	0.00188987562707646	Chronic myeloid leukemia: CDKN1B
hsa04931__47	0.00126571574562878	DOWN	-3.22492877545896	0.00192261914796805	Insulin resistance: AKT2*
hsa04621__6	0.00131197755787586	UP	3.21463371153092	0.00198967379438963	NOD-like receptor signaling pathway: NFKB1
hsa05168__9	0.00131197755787586	UP	3.21463371153092	0.00198967379438963	Herpes simplex infection: NFKB1
hsa04020__16	0.00133568904794797	DOWN	-3.2094861795669	0.002023999775076	Calcium signaling pathway: C06124
hsa04014__69	0.00138430244071443	DOWN	-3.19919111563886	0.00209597444488511	Ras signaling pathway: PLCE1*
hsa04211__57	0.00140921627065617	DOWN	-3.19404358367484	0.00213197856083973	Longevity regulating pathway - mammal: ATG5
hsa04012__25	0.00148645949385654	UP	3.17860098778278	0.00224702927510574	ErbB signaling pathway: CDKN1B
hsa04010__129	0.0015265269933193	DOWN	-3.17087968983675	0.00230389094011804	MAPK signaling pathway: FOS
hsa04930__26	0.0015265269933193	DOWN	-3.17087968983675	0.00230389094011804	Type II diabetes mellitus: INS*
hsa04066__11	0.00156758717216589	DOWN	-3.16315839189072	0.00236206599558918	HIF-1 signaling pathway: SLC2A1
hsa05200__194	0.00156758717216589	UP	3.16315839189072	0.00236206599558918	Pathways in cancer: BCL2
hsa04530__4 37 11	0.00158149829894577	DOWN	-3.16058462590871	0.0023792116122651	Tight junction: OCLN TJP3 TJP1
hsa05211__4	0.00158149829894577	DOWN	-3.16058462590871	0.0023792116122651	Renal cell carcinoma: SLC2A1
hsa04970__45	0.00159551667840524	UP	3.1580108599267	0.00239647299857998	Salivary secretion: KCNMA1
hsa05162__27 70	0.00159552300224777	UP	3.1580108599267	0.00239647299857998	Measles: STAT1 GNB2L1
hsa04660__44	0.00160966211569869	UP	3.15543709394468	0.00241385085027761	T cell receptor signaling pathway: PAK4
hsa05205__22	0.00160966211569869	UP	3.15543709394468	0.00241385085027761	Proteoglycans in cancer: PPP1R12A
hsa04068__68	0.00162391647820395	DOWN	-3.15286332796267	0.00243328473887178	FoxO signaling pathway: ATG12
hsa04931__77	0.0016373013887629	UP	3.15028956198066	0.00244895875014858	Insulin resistance: PPP2R4**
hsa05164__19	0.00163828693397379	UP	3.15028956198066	0.00244895875014858	Influenza A: NFKB1
hsa05218__9	0.00163828693397379	DOWN	-3.15028956198066	0.00244895875014858	Melanoma: CCND1
hsa04152__60	0.00169694676105497	UP	3.13999449805262	0.00253462874723552	AMPK signaling pathway: EEF2
hsa04919__38	0.00171191053382353	UP	3.13742073207061	0.00255494828677873	Thyroid hormone signaling pathway: TP53
hsa05200__224	0.00174220277568119	UP	3.13227320010659	0.00259603411221646	Pathways in cancer: MYC***
hsa05221__12	0.00174220277568119	UP	3.13227320010659	0.00259603411221646	Acute myeloid leukemia: MYC
hsa04925__34	0.00175753301446248	DOWN	-3.12969943412458	0.0026168023250198	Aldosterone synthesis and secretion: STAR
hsa04510__19 26	0.00180427093681248	DOWN	-3.12197813617855	0.00268426372943045	Focal adhesion: VCL ACTN4
hsa05200__223	0.00182010232736129	DOWN	-3.11940437019654	0.00270353539376431	Pathways in cancer: CCND1****
hsa05221__17	0.00182010232736129	DOWN	-3.11940437019654	0.00270353539376431	Acute myeloid leukemia: CCND1
hsa04024__12	0.00186836556690155	UP	3.11168307225051	0.00277303230664141	cAMP signaling pathway: SLC9A1
hsa05211__40	0.00191780193556825	UP	3.10396177430448	0.00284415930302505	Renal cell carcinoma: PAK4
hsa04068__40	0.00198558609700991	DOWN	-3.09366671037644	0.00294236299391294	FoxO signaling pathway: CCND1
hsa04919__25	0.00212779577035216	DOWN	-3.07307658252035	0.00315061328013531	Thyroid hormone signaling pathway: MTOR
hsa05150__35	0.0021834734239752	UP	3.06535528457432	0.00323050910523575	Staphylococcus aureus infection: FCAR
hsa04727__13	0.00222135815729065	UP	3.0602077526103	0.00328397480531009	GABAergic synapse: CACNA1A
hsa04540__11	0.00224051717726475	DOWN	-3.05763398662829	0.00330969479251609	Gap junction: C00780
hsa04340__15	0.00225982750250735	DOWN	-3.05506022064628	0.00333559770401516	Hedgehog signaling pathway: HHIP
hsa05145__33	0.00227929019900084	UP	3.05248645466427	0.00335904806582163	Toxoplasmosis: STAT3
hsa05169__125	0.00227929019900084	UP	3.05248645466427	0.00335904806582163	Epstein-Barr virus infection: STAT3
hsa04010__88 92	0.00229890633911229	UP	3.04991268868226	0.00338265075269537	MAPK signaling pathway: ECSIT TRAF6
hsa05205__183	0.00229890633911229	UP	3.04991268868226	0.00338265075269537	Proteoglycans in cancer: VEGFA*
hsa04520__73	0.00231867700162237	UP	3.04733892270025	0.00340907205481097	Adherens junction: PARD3
hsa04066__58	0.00233860327175438	DOWN	-3.04476515671824	0.00343299652158318	HIF-1 signaling pathway: EDN1
hsa05321__152	0.00233860327175438	UP	3.04476515671824	0.00343299652158318	Inflammatory bowel disease (IBD): FOXP3*
hsa04210__51	0.00254666780627702	DOWN	-3.01902749689814	0.0037325965740987	Apoptosis: LMNA
hsa05130__28	0.00254666780627702	UP	3.01902749689814	0.0037325965740987	Pathogenic Escherichia coli infection: ROCK1
hsa04066__26	0.00256837925680186	UP	3.01645373091613	0.00376148450781816	HIF-1 signaling pathway: C01245
hsa04540__18 19	0.00259025985079409	UP	3.01387996493412	0.00378762510477985	Gap junction: GJA1 GJA1***
hsa05200__66	0.00259025985079409	UP	3.01387996493412	0.00378762510477985	Pathways in cancer: CCND1
hsa04950__20	0.00274825931135733	DOWN	-2.99586360306004	0.00401553596115118	Maturity onset diabetes of the young: NKX6-1
hsa04520__44 52 45	0.00279499224982945	DOWN	-2.99071607109602	0.004080645250528	Adherens junction: ACTB ACTN4 CTNNA1
hsa04380__20	0.0030652471211509	UP	2.96240464529391	0.00446480569042057	Osteoclast differentiation: MAP2K1
hsa04530__20 37	0.0030652471211509	DOWN	-2.96240464529391	0.00446480569042057	Tight junction: ACTB TJP3
hsa05213__12	0.0030652471211509	UP	2.96240464529391	0.00446480569042057	Endometrial cancer: BAD
hsa04922__17	0.00311687173474492	DOWN	-2.95725711332989	0.00453648488736306	Glucagon signaling pathway: PKM
hsa04211__51	0.00314298019494389	UP	2.95468334734788	0.00456387927843862	Longevity regulating pathway - mammal: NFKB1
hsa04350__44 45	0.00314298019494389	UP	2.95468334734788	0.00456387927843862	TGF-beta signaling pathway: TGFBR2 TGFBR1
hsa04360__4	0.00314298019494389	DOWN	-2.95468334734788	0.00456387927843862	Axon guidance: GNAI1*
hsa04360__59	0.00316928787080699	DOWN	-2.95210958136587	0.00459497832503576	Axon guidance: MAPK1*
hsa04724__66	0.00316928787080699	DOWN	-2.95210958136587	0.00459497832503576	Glutamatergic synapse: PLA2G4B
hsa04380__48	0.00319579610681343	UP	2.94953581538386	0.00462983877000959	Osteoclast differentiation: NFATC1
hsa04550__67	0.00322250625502496	UP	2.94696204940185	0.0046649377913651	Signaling pathways regulating pluripotency of stem cells: MYC*
hsa05221__13	0.00333139327827345	DOWN	-2.93666698547381	0.00481885140098215	Acute myeloid leukemia: NFKB1
hsa04910__26	0.00347221052142769	UP	2.92379815556375	0.00501867966904818	Insulin signaling pathway: RPS6
hsa04932__95	0.00350101584532199	UP	2.92122438958174	0.00505642488344351	Non-alcoholic fatty liver disease (NAFLD): IL1A
hsa04024__113	0.00353003846338413	DOWN	-2.91865062359973	0.00509442570867802	cAMP signaling pathway: PTCH1
hsa04920__12	0.00370881885601316	DOWN	-2.90320802770767	0.00534832742167976	Adipocytokine signaling pathway: C00165
hsa03320__66	0.00405810094743717	DOWN	-2.87489660190556	0.00584752429465831	PPAR signaling pathway: UCP1
hsa05016__22 9	0.00433059516798919	UP	2.85430647404947	0.00623539334915838	Huntington's disease: DLG4 HTT
hsa04530__11 20 16	0.0043657986980989	DOWN	-2.85173270806746	0.00628126780530461	Tight junction: TJP1 ACTB CTTN
hsa04064__135	0.00440126144424839	DOWN	-2.84915894208545	0.0063274447235981	NF-kappa B signaling pathway: CCL19
hsa03320__43	0.00443698507849333	UP	2.84658517610344	0.00636905650304734	PPAR signaling pathway: ILK
hsa04664__23	0.00443698507849333	UP	2.84658517610344	0.00636905650304734	Fc epsilon RI signaling pathway: AKT3
hsa04062__60	0.00454573816302123	UP	2.83886387815741	0.0065201847391732	Chemokine signaling pathway: GSK3A
hsa05205__188	0.00458252224730955	UP	2.8362901121754	0.00656793234377929	Proteoglycans in cancer: TNF
hsa04622__6	0.00461957571307522	UP	2.83371634619339	0.00661599296102769	RIG-I-like receptor signaling pathway: NFKB1
hsa04660__43	0.00465690028583517	UP	2.83114258021138	0.00665929652746141	T cell receptor signaling pathway: RHOA
hsa04722__37	0.00465690028583517	UP	2.83114258021138	0.00665929652746141	Neurotrophin signaling pathway: NFKB1
hsa05200__207	0.00469449770012643	DOWN	-2.82856881422937	0.00670795526884986	Pathways in cancer: CDK4
hsa04915__58	0.00477051803673969	DOWN	-2.82342128226535	0.00681140075306526	Estrogen signaling pathway: CREB3***
hsa04510__19 23	0.00496546677285969	DOWN	-2.8105524523553	0.00708436755216655	Focal adhesion: VCL TLN1
hsa04022__9	0.00500531045549226	UP	2.80797868637329	0.00712498359535603	cGMP-PKG signaling pathway: ITPR1
hsa04024__44 67	0.00500531045549226	UP	2.80797868637329	0.00712498359535603	cAMP signaling pathway: CREB3 CREBBP
hsa04024__59	0.00500531045549226	DOWN	-2.80797868637329	0.00712498359535603	cAMP signaling pathway: MLLT4
hsa04933__35	0.00508586623754048	UP	2.80283115440927	0.00723417309639559	AGE-RAGE signaling pathway in diabetic complications: CCND1
hsa04666__42	0.0051265819992427	DOWN	-2.80025738842726	0.0072810639278738	Fc gamma R-mediated phagocytosis: MYO10
hsa04933__12	0.0051265819992427	UP	2.80025738842726	0.0072810639278738	AGE-RAGE signaling pathway in diabetic complications: EGR1
hsa04660__14	0.00516759213189313	UP	2.79768362244525	0.00732823065345449	T cell receptor signaling pathway: NFKB1
hsa04728__60	0.00516759213189313	UP	2.79768362244525	0.00732823065345449	Dopaminergic synapse: CACNA1A
hsa04350__10	0.0052924073493309	DOWN	-2.78996232449922	0.00749957270693271	TGF-beta signaling pathway: SMAD4
hsa05220__50	0.00533461360698491	DOWN	-2.78738855851721	0.00755368422571564	Chronic myeloid leukemia: MAPK1
hsa04920__37	0.00537712360371482	DOWN	-2.7848147925352	0.00760814401459348	Adipocytokine signaling pathway: IRS1
hsa04261__72	0.0055064950989323	DOWN	-2.77709349458916	0.00778533054243326	Adrenergic signaling in cardiomyocytes: ATP2B1
hsa04530__7 52	0.00577369889015263	DOWN	-2.7616508986971	0.00815697760496	Tight junction: PARD6A MPP5
hsa04066__44	0.00591163731506987	DOWN	-2.75392960075107	0.00834557965065086	HIF-1 signaling pathway: GAPDH
hsa04066__45	0.00595827255438929	DOWN	-2.75135583476906	0.00839879529609714	HIF-1 signaling pathway: ALDOA
hsa04722__84	0.00595827255438929	DOWN	-2.75135583476906	0.00839879529609714	Neurotrophin signaling pathway: NFKB1*
hsa04350__34	0.00619645854292104	UP	2.73848700485901	0.00872799520400948	TGF-beta signaling pathway: ROCK1
hsa05210__39	0.00634345230364188	UP	2.73076570691298	0.00892834972175512	Colorectal cancer: BAD
hsa05200__5	0.00644318392621854	DOWN	-2.72561817494896	0.00905515527102815	Pathways in cancer: CASP3*
hsa05210__7	0.00644318392621854	DOWN	-2.72561817494896	0.00905515527102815	Colorectal cancer: CASP3*
hsa04062__40	0.00701734814068397	DOWN	-2.69730674914684	0.00984734664402179	Chemokine signaling pathway: PRKACA
hsa05221__26	0.00701734814068397	UP	2.69730674914684	0.00984734664402179	Acute myeloid leukemia: BAD
hsa04728__61	0.00712654608672508	DOWN	-2.69215921718282	0.0099856674846804	Dopaminergic synapse: KCNJ3
hsa05213__11	0.00712654608672508	UP	2.69215921718282	0.0099856674846804	Endometrial cancer: FOXO3
hsa04213__61	0.00729320444477477	DOWN	-2.68443791923679	0.0102115731383992	Longevity regulating pathway - multiple species: ATG5
hsa04911__25	0.00746335152868745	DOWN	-2.67671662129076	0.0104420234716334	Insulin secretion: PRKCA
hsa04024__2	0.00752085330316202	UP	2.67414285530875	0.0105146453546439	cAMP signaling pathway: CACNA1C
hsa05205__109	0.0078143634544227	UP	2.6612740253987	0.0109087584924668	Proteoglycans in cancer: SMAD2
hsa05217__4	0.0078143634544227	DOWN	-2.6612740253987	0.0109087584924668	Basal cell carcinoma: PTCH1
hsa04950__16	0.00811809452550646	UP	2.64840519548865	0.0113243501213264	Maturity onset diabetes of the young: PAX4
hsa04664__30	0.00818009386891471	UP	2.64583142950664	0.011402371201551	Fc epsilon RI signaling pathway: PRKCA
hsa04919__87	0.00830536533302745	UP	2.64068389754262	0.0115684073096802	Thyroid hormone signaling pathway: BAD
hsa04913__45	0.0084323503935607	DOWN	-2.6355363655786	0.0117365825107411	Ovarian steroidogenesis: ACOT2
hsa04151__24	0.0084964917747041	UP	2.63296259959658	0.0118171044001991	PI3K-Akt signaling pathway: MYC
hsa04071__1	0.00862608484204727	DOWN	-2.62781506763256	0.0119884714631707	Sphingolipid signaling pathway: MAPK1
hsa05231__38	0.00869154160359252	DOWN	-2.62524130165055	0.0120705149099411	Choline metabolism in cancer: RPS6KB1
hsa05166__62 63	0.00895782991302924	UP	2.61494623772251	0.0124311391481403	HTLV-I infection: ANAPC10 CDC20
hsa04710__5	0.00916230296606955	UP	2.60722493977648	0.0127055109027636	Circadian rhythm: RORA
hsa04621__30 32	0.0093009227557365	UP	2.60207740781246	0.0128882255590183	NOD-like receptor signaling pathway: PYCARD CASP1
hsa04012__43	0.0095123621240262	DOWN	-2.59435610986643	0.0131618029683691	ErbB signaling pathway: PTK2
hsa04151__25	0.0095123621240262	DOWN	-2.59435610986643	0.0131618029683691	PI3K-Akt signaling pathway: CDKN1B
hsa04666__49	0.00965569277908674	UP	2.58920857790241	0.0133502919292892	Fc gamma R-mediated phagocytosis: ARF6*
hsa03320__65	0.00987429959661415	DOWN	-2.58148727995638	0.0136425065750279	PPAR signaling pathway: ME1
hsa05168__39 40	0.0100973052582253	DOWN	-2.57376598201035	0.0139403648642214	Herpes simplex infection: POU2F3 HCFC2
hsa05220__15	0.010172630926595	UP	2.57119221602834	0.0140340480991718	Chronic myeloid leukemia: MYC
hsa05213__27	0.0104016184722418	DOWN	-2.5634709180823	0.0143394285468396	Endometrial cancer: ELK1
hsa04350__50	0.0104789605798957	UP	2.56089715210029	0.0144354596258241	TGF-beta signaling pathway: AMHR2
hsa04921__28	0.0106351812518276	DOWN	-2.55574962013627	0.0146399308221129	Oxytocin signaling pathway: EEF2
hsa04950__13	0.0107140655475214	DOWN	-2.55317585415426	0.0147377226674911	Maturity onset diabetes of the young: INS
hsa04530__8	0.0109538489155103	DOWN	-2.54545455620823	0.0150565340982033	Tight junction: LLGL2
hsa05223__21	0.0110348298918748	UP	2.54288079022622	0.0151567583090883	Non-small cell lung cancer: FOXO3*
hsa04390__88	0.0111163423388102	DOWN	-2.54030702424421	0.01525756556218	Hippo signaling pathway: ID1
hsa04728__54	0.0116167436490858	UP	2.52486442835215	0.0159327454865929	Dopaminergic synapse: CAMK2A
hsa04550__62 63	0.0117020595204582	UP	2.52229066237014	0.0160380523989358	Signaling pathways regulating pluripotency of stem cells: SMAD2 SMAD4
hsa05134__70	0.0119613515333785	DOWN	-2.51456936442411	0.0163814719615294	Legionellosis: IL6
hsa05200__204	0.0123149922166579	DOWN	-2.50427430049607	0.0168535108340133	Pathways in cancer: TGFB1*
hsa04913__35	0.0124952617034279	DOWN	-2.49912676853205	0.0170877705536689	Ovarian steroidogenesis: HSD17B2
hsa05217__5	0.0125862696759063	UP	2.49655300255004	0.0171997096152931	Basal cell carcinoma: BMP2
hsa04068__43	0.0127700478522548	UP	2.49140547058602	0.0174381685424322	FoxO signaling pathway: CDKN1A
hsa04976__34	0.0128628244030121	UP	2.48883170460401	0.0175521038876251	Bile secretion: SLCO1B1
hsa04064__97	0.0129561968476825	DOWN	-2.48625793862199	0.0176538751825927	NF-kappa B signaling pathway: PLCG2
hsa05211__21	0.0129561968476825	DOWN	-2.48625793862199	0.0176538751825927	Renal cell carcinoma: TGFB1*
hsa05215__43	0.0132398207071109	DOWN	-2.47853664067596	0.0180143467004122	Prostate cancer: C05981
hsa05231__60	0.0132399216568756	DOWN	-2.47853664067596	0.0180143467004122	Choline metabolism in cancer: PRKCA
hsa05160__22 23	0.0133357098519712	UP	2.47596287469395	0.0181315476207337	Hepatitis C: STAT1 IRF9
hsa04973__5	0.0137250158203948	DOWN	-2.46566781076591	0.0186473642274199	Carbohydrate digestion and absorption: SLC2A5
hsa04151__26	0.0140235483601343	DOWN	-2.45794651281988	0.0190391960756447	PI3K-Akt signaling pathway: RBL2
hsa04310__35	0.0141243251268723	DOWN	-2.45537274683787	0.0191621710566015	Wnt signaling pathway: JUN
hsa04921__55	0.0142257404382551	DOWN	-2.45279898085586	0.0192858342593661	Oxytocin signaling pathway: PTGS2*
hsa04510__26 4 5	0.0143277976641909	DOWN	-2.45022521487385	0.0193962044747944	Focal adhesion: ACTN4 ITGB1 ITGA11
hsa04950__31	0.0143277976641909	UP	2.45022521487385	0.0193962044747944	Maturity onset diabetes of the young: NKX6-1*
hsa05162__20	0.0146378547204609	UP	2.44250391692782	0.0198016767600764	Measles: NFKB1
hsa05161__68	0.0148478313556167	UP	2.4373563849638	0.0200712770627365	Hepatitis B: JUN
hsa04510__6 4 5	0.0152757612332182	DOWN	-2.42706132103576	0.0206349067988619	Focal adhesion: FLNA ITGB1 ITGA11
hsa04950__30	0.015714512484685	UP	2.41676625710772	0.0212123340220711	Maturity onset diabetes of the young: PAX6*
hsa04360__19	0.0158259175455207	UP	2.4141924911257	0.0213473790868868	Axon guidance: CDC42
hsa04010__14	0.0161643110824511	UP	2.40647119317967	0.0217569774526688	MAPK signaling pathway: MAPT
hsa04350__21	0.0161643110824511	DOWN	-2.40647119317967	0.0217569774526688	TGF-beta signaling pathway: CDKN2B
hsa04921__48	0.0161643110824511	UP	2.40647119317967	0.0217569774526688	Oxytocin signaling pathway: PRKAG2
hsa04360__21	0.0162785136767406	UP	2.40389742719766	0.021895008731994	Axon guidance: PAK4
hsa04068__72	0.0163934246597584	DOWN	-2.40132366121565	0.0220337946607196	FoxO signaling pathway: SMAD2
hsa04670__73	0.0173386526323651	UP	2.38073353335957	0.02327094878301	Leukocyte transendothelial migration: MYL12B*
hsa04971__49	0.0173386526323651	DOWN	-2.38073353335957	0.02327094878301	Gastric acid secretion: KCNJ1
hsa05205__34	0.0177052460989452	UP	2.37301223541354	0.023746008151262	Proteoglycans in cancer: SLC9A1
hsa05166__39	0.0178289444713248	UP	2.37043846943153	0.0238948549654916	HTLV-I infection: RRAS2
hsa04660__35	0.0182045942268186	UP	2.3627171714855	0.0243809212773999	T cell receptor signaling pathway: NFATC1
hsa04024__21	0.018587156109197	DOWN	-2.35499587353947	0.0248755458185051	cAMP signaling pathway: AKT3
hsa04210__85	0.0191081706528141	UP	2.34470080961143	0.0255364528141094	Apoptosis: FASLG*
hsa05169__93	0.0191081706528141	DOWN	-2.34470080961143	0.0255364528141094	Epstein-Barr virus infection: PLCG1
hsa04390__89	0.019373433155702	DOWN	-2.33955327764741	0.0258725521674229	Hippo signaling pathway: ID2
hsa04152__68	0.0196419077227352	DOWN	-2.33440574568338	0.0261752798659712	AMPK signaling pathway: PPARGC1A**
hsa05200__225	0.0196419077227352	UP	2.33440574568338	0.0261752798659712	Pathways in cancer: PPARD
hsa05221__11	0.0196419077227352	UP	2.33440574568338	0.0261752798659712	Acute myeloid leukemia: PPARD
hsa04390__78	0.0197773594268114	DOWN	-2.33183197970137	0.0263371072735497	Hippo signaling pathway: SOX2
hsa04910__9	0.0199136260489814	UP	2.32925821371936	0.0264997899051247	Insulin signaling pathway: ELK1
hsa05222__32	0.0201886200395177	DOWN	-2.32411068175534	0.0268467211990473	Small cell lung cancer: BIRC8
hsa04024__3	0.0207485636836932	UP	2.3138156178273	0.0275718183604381	cAMP signaling pathway: RYR2
hsa04510__20 4 5	0.0208906473189403	UP	2.31124185184529	0.0277214168872096	Focal adhesion: VASP ITGB1 ITGA11
hsa04622__5 33	0.0208906473189403	DOWN	-2.31124185184529	0.0277214168872096	RIG-I-like receptor signaling pathway: MAVS TMEM173
hsa04923__43	0.0213219980948614	UP	2.30352055389926	0.028253902976195	Regulation of lipolysis in adipocytes: C00219
hsa05205__415	0.0213219980948614	DOWN	-2.30352055389926	0.028253902976195	Proteoglycans in cancer: MAPK1******
hsa05215__12	0.0214674953527307	DOWN	-2.30094678791725	0.0284266552274707	Prostate cancer: KLK3
hsa04933__22	0.0217610851813717	UP	2.29579925595323	0.028795126095632	AGE-RAGE signaling pathway in diabetic complications: EDN1
hsa04360__82	0.0222080206835589	UP	2.2880779580072	0.0293658486026792	Axon guidance: ILK
hsa05164__36	0.0223587628055019	UP	2.28550419202519	0.0295443848885641	Influenza A: IL33
hsa05142__21	0.0231258906520987	UP	2.27263536211514	0.0305365766235373	Chagas disease (American trypanosomiasis): TICAM1
hsa04622__44	0.0232820294647851	UP	2.27006159613313	0.0307211610704573	RIG-I-like receptor signaling pathway: MAPK8
hsa04261__3	0.0240765260051906	DOWN	-2.25719276622307	0.0317472227114057	Adrenergic signaling in cardiomyocytes: RYR2
hsa04750__7	0.0245643697233748	UP	2.24947146827704	0.0323450951017668	Inflammatory mediator regulation of TRP channels: TRPV1
hsa04750__58	0.0245643697233748	UP	2.24947146827704	0.0323450951017668	Inflammatory mediator regulation of TRP channels: TRPV1**
hsa04151__28	0.0255659637531681	DOWN	-2.23402887238498	0.0336403682718507	PI3K-Akt signaling pathway: BCL2L11
hsa04913__40	0.0262531170731798	DOWN	-2.22373380845694	0.0345203687757207	Ovarian steroidogenesis: HSD17B1
hsa04310__34	0.0264273789546849	UP	2.22116004247493	0.0347252063327643	Wnt signaling pathway: FOSL1
hsa05166__34 35 36	0.0267788470259343	UP	2.21601251051091	0.0351624413429284	HTLV-I infection: MYC TRRAP KAT5
hsa04933__58	0.0271344569078469	UP	2.21086497854689	0.035604500370003	AGE-RAGE signaling pathway in diabetic complications: CCL2
hsa04668__40	0.0291636981581606	DOWN	-2.18255355274477	0.0382137997483848	TNF signaling pathway: JUN
hsa04724__68	0.0291636981581606	DOWN	-2.18255355274477	0.0382137997483848	Glutamatergic synapse: MAPK1
hsa04921__43	0.0293544892778898	UP	2.17997978676276	0.0384369932774599	Oxytocin signaling pathway: CACNG3
hsa04810__31	0.0299333188011144	DOWN	-2.17225848881673	0.0391676225816811	Regulation of actin cytoskeleton: MSN
hsa04530__13 45 20	0.0303246329890614	DOWN	-2.16711095685271	0.0396520427184735	Tight junction: EPB41 TJP2 ACTB
hsa04670__76	0.0307203342009692	DOWN	-2.16196342488869	0.0401415215324208	Leukocyte transendothelial migration: CDC42
hsa04750__60	0.0309196884341598	UP	2.15938965890668	0.040373936461283	Inflammatory mediator regulation of TRP channels: TRPV3
hsa05168__138	0.0311204610174587	UP	2.15681589292467	0.0406078793415312	Herpes simplex infection: CHUK
hsa05162__25 70	0.0323477838299306	UP	2.14137329703261	0.0421800734326437	Measles: IFNAR1 GNB2L1
hsa04210__69	0.0327660027701528	UP	2.13622576506859	0.0426957830826055	Apoptosis: PTPN13
hsa04152__103	0.0329768427948695	UP	2.13365199908658	0.0429407398555508	AMPK signaling pathway: ULK1
hsa05200__121 122	0.033188843134136	DOWN	-2.13107823310457	0.0431271343354367	Pathways in cancer: SMAD2 SMAD4
hsa05212__38 39	0.033188843134136	DOWN	-2.13107823310457	0.0431271343354367	Pancreatic cancer: SMAD2 SMAD4
hsa05220__19 41	0.033188843134136	DOWN	-2.13107823310457	0.0431271343354367	Chronic myeloid leukemia: SMAD4 SMAD3
hsa05221__5	0.0338318558332902	UP	2.12335693515854	0.0439323131380458	Acute myeloid leukemia: SPI1
hsa03320__45	0.0340485472839579	DOWN	-2.12078316917653	0.0441831632227603	PPAR signaling pathway: PDPK1
hsa04724__51	0.0342664240348011	DOWN	-2.11820940319452	0.044404559145787	Glutamatergic synapse: ADRBK1
hsa05212__54	0.0342664240348011	UP	2.11820940319452	0.044404559145787	Pancreatic cancer: C00416
hsa04723__40	0.0347057535783616	DOWN	-2.11306187123049	0.0448810123700904	Retrograde endocannabinoid signaling: GRIA1
hsa04724__4	0.0347057535783616	DOWN	-2.11306187123049	0.0448810123700904	Glutamatergic synapse: GRIA1
hsa05031__12	0.0347057535783616	DOWN	-2.11306187123049	0.0448810123700904	Amphetamine addiction: GRIA1
hsa04921__33	0.0355988584744563	DOWN	-2.10276680730245	0.0459411092537797	Oxytocin signaling pathway: C00942
hsa05030__80 81	0.0355988584744563	DOWN	-2.10276680730245	0.0459411092537797	Cocaine addiction: GRIN3A DLG4
hsa05152__13	0.0355988584744563	DOWN	-2.10276680730245	0.0459411092537797	Tuberculosis: LAMP1
hsa04662__35	0.0367427456803244	DOWN	-2.0898979773924	0.0473522764974826	B cell receptor signaling pathway: CD79B
hsa04810__29	0.0367427456803244	DOWN	-2.0898979773924	0.0473522764974826	Regulation of actin cytoskeleton: ACTN4
hsa04211__62	0.0369752418755044	UP	2.08732421141039	0.0476192457053275	Longevity regulating pathway - mammal: EHMT2
hsa05120__52	0.0372089896924899	UP	2.08475044542838	0.047887460022047	Epithelial cell signaling in Helicobacter pylori infection: LYN
hsa05145__10	0.0374439943125327	UP	2.08217667944637	0.0481569235545851	Toxoplasmosis: MAPK8
hsa04913__64	0.0376802609280472	DOWN	-2.07960291346436	0.0484276404129964	Ovarian steroidogenesis: PLA2G4B
hsa04550__36	0.0381566009707026	DOWN	-2.07445538150034	0.0489728505628075	Signaling pathways regulating pluripotency of stem cells: AKT3*
hsa05223__22	0.0381566009707026	UP	2.07445538150034	0.0489728505628075	Non-small cell lung cancer: BAD*
hsa04740__33	0.0386380515813625	UP	2.06930784953632	0.0495569275913858	Olfactory transduction: CNGA3*
hsa05161__92	0.0398643124810168	DOWN	-2.05643901962627	0.0510948452604574	Hepatitis B: NFKBIA
hsa04210__71	0.0401134870580888	UP	2.05386525364426	0.0513441704238071	Apoptosis: GADD45G
hsa04340__51	0.0401134870580888	UP	2.05386525364426	0.0513441704238071	Hedgehog signaling pathway: CCND1*
hsa05160__58	0.0403639814711201	UP	2.05129148766225	0.0516296264017935	Hepatitis C: EIF3E
hsa05166__60	0.0406158010429349	DOWN	-2.04871772168024	0.0519163878637243	HTLV-I infection: POLD3
hsa04151__97	0.0413792640973552	UP	2.0409964237342	0.0527845466659405	PI3K-Akt signaling pathway: MCL1
hsa04726__16	0.0413792640973552	DOWN	-2.0409964237342	0.0527845466659405	Serotonergic synapse: ITPR1
hsa04726__46	0.0413792640973552	DOWN	-2.0409964237342	0.0527845466659405	Serotonergic synapse: ITPR1*
hsa04310__20	0.0421548462100574	DOWN	-2.03327512578817	0.0537009871381002	Wnt signaling pathway: MAPK8
hsa05145__8	0.0421548462100574	UP	2.03327512578817	0.0537009871381002	Toxoplasmosis: NFKB1
hsa04725__53	0.0426786675722963	UP	2.02812759382415	0.0542947106942464	Cholinergic synapse: CHRNA7
hsa05031__55	0.0426787055324119	DOWN	-2.02812759382415	0.0542947106942464	Amphetamine addiction: GRIA1*
hsa04723__7	0.0432080589970221	DOWN	-2.02298006186013	0.0548938085567306	Retrograde endocannabinoid signaling: ITPR1
hsa04915__28	0.0432080589970221	DOWN	-2.02298006186013	0.0548938085567306	Estrogen signaling pathway: KCNJ3
hsa04920__28	0.0440124857976334	DOWN	-2.0152587639141	0.0558780140633468	Adipocytokine signaling pathway: SLC2A1
hsa04540__10	0.0448295195238374	UP	2.00753746596807	0.0568385068726657	Gap junction: C00533
hsa04950__18	0.0448295195238374	DOWN	-2.00753746596807	0.0568385068726657	Maturity onset diabetes of the young: SLC2A2
hsa04510__43	0.0459387646916091	UP	1.99724240204003	0.0582056229639471	Focal adhesion: BAD
hsa04932__35	0.0462196603993513	DOWN	-1.99466863605802	0.0585220632684509	Non-alcoholic fatty liver disease (NAFLD): PRKAG2
hsa04012__57	0.0476459226734499	DOWN	-1.98179980614797	0.0602062466061953	ErbB signaling pathway: ABL1
hsa04728__36	0.0476459226734499	UP	1.98179980614797	0.0602062466061953	Dopaminergic synapse: TH
hsa05217__19	0.0476459226734499	DOWN	-1.98179980614797	0.0602062466061953	Basal cell carcinoma: HHIP
hsa04014__63	0.04793557086718	DOWN	-1.97922604016596	0.0605315441259619	Ras signaling pathway: TIAM1*
hsa05164__53	0.0485193077192476	DOWN	-1.97407850820194	0.061186428996286	Influenza A: MAPK14
hsa05168__91 92	0.0485193077192476	UP	1.97407850820194	0.061186428996286	Herpes simplex infection: STAT1 IRF9
hsa04725__43	0.0491090026113025	DOWN	-1.96893097623792	0.0618470615996229	Cholinergic synapse: CREB3
hsa04976__38	0.0491090026113025	DOWN	-1.96893097623792	0.0618470615996229	Bile secretion: ABCC2
hsa04012__56	0.0503064467645166	DOWN	-1.95863591230987	0.0633126680981424	ErbB signaling pathway: JUN
hsa05205__220	0.0524608435462692	UP	1.9406195504358	0.0659798694936009	Proteoglycans in cancer: FAS
hsa05200__185	0.0530903693301331	UP	1.93547201847178	0.0667269591781405	Pathways in cancer: HHIP
hsa05168__106 134	0.0537261941403402	DOWN	-1.93032448650776	0.0674809617578204	Herpes simplex infection: SRSF8 C1QBP
hsa04115__52 53	0.0540464830543556	UP	1.92775072052575	0.067837903579916	p53 signaling pathway: CDK4 CCND1
hsa04972__23	0.0543683639890443	DOWN	-1.92517695454374	0.0681963657779802	Pancreatic secretion: KCNMA1
hsa04024__114	0.0553436166586319	DOWN	-1.91745565659771	0.0693733527028481	cAMP signaling pathway: HHIP
hsa05134__72	0.0580157831879657	UP	1.89686552874163	0.072674437740125	Legionellosis: IL12A
hsa05211__43	0.0597397044715735	DOWN	-1.88399669883157	0.0747840804144481	Renal cell carcinoma: RAP1A
hsa04971__39	0.0600895384484537	UP	1.88142293284956	0.075071969910003	Gastric acid secretion: EZR
hsa05205__352	0.0600895384484537	DOWN	-1.88142293284956	0.075071969910003	Proteoglycans in cancer: ITGA5*
hsa05210__22	0.0600895384484537	UP	1.88142293284956	0.075071969910003	Colorectal cancer: MYC
hsa04520__69	0.0618642806346004	DOWN	-1.86855410293951	0.0771865759046575	Adherens junction: IQGAP1**
hsa05231__18	0.0618642806346004	UP	1.86855410293951	0.0771865759046575	Choline metabolism in cancer: CHKA
hsa05200__199	0.0622243848552546	UP	1.8659803369575	0.0775329039409969	Pathways in cancer: BCL2L1**
hsa05220__3	0.0622243848552546	UP	1.8659803369575	0.0775329039409969	Chronic myeloid leukemia: BCL2L1
hsa03320__23	0.0629497964088172	DOWN	-1.86083280499348	0.0783848028178711	PPAR signaling pathway: ACADL
hsa03320__62	0.0633151155987324	UP	1.85825903901147	0.0787353422965044	PPAR signaling pathway: UBC
hsa04950__8	0.0633151155987324	DOWN	-1.85825903901147	0.0787353422965044	Maturity onset diabetes of the young: NEUROD1
hsa04014__42	0.0644215980741567	DOWN	-1.85053774106544	0.080058321945331	Ras signaling pathway: PLA2G4B
hsa05211__2	0.0647939536903905	DOWN	-1.84796397508343	0.0804678380596455	Renal cell carcinoma: TGFB1
hsa04340__20 22	0.0651680832925816	UP	1.84539020910142	0.0808256293773999	Hedgehog signaling pathway: GLI1 SUFU*
hsa04740__10	0.0651680832925816	DOWN	-1.84539020910142	0.0808256293773999	Olfactory transduction: ANO2
hsa04724__44	0.0663011756537733	DOWN	-1.83766891115539	0.0820684512868511	Glutamatergic synapse: PRKACA*
hsa04921__54	0.0663011756537733	DOWN	-1.83766891115539	0.0820684512868511	Oxytocin signaling pathway: RCAN1
hsa04933__26	0.0663011756537733	DOWN	-1.83766891115539	0.0820684512868511	AGE-RAGE signaling pathway in diabetic complications: IL6
hsa05132__41	0.0678371634667562	DOWN	-1.82737384722735	0.0838592303644966	Salmonella infection: ACTB*
hsa05220__4	0.0678371634667562	UP	1.82737384722735	0.0838592303644966	Chronic myeloid leukemia: PTPN11
hsa04340__52	0.0701959194983165	UP	1.81193125133528	0.0866610596171726	Hedgehog signaling pathway: BCL2*
hsa05223__23	0.0701959194983165	DOWN	-1.81193125133528	0.0866610596171726	Non-small cell lung cancer: CASP9*
hsa04115__3	0.0718055002848089	UP	1.80163618740724	0.088531847135929	p53 signaling pathway: GADD45G
hsa05014__49	0.0718055002848089	DOWN	-1.80163618740724	0.088531847135929	Amyotrophic lateral sclerosis (ALS): C00001
hsa04110__43 83 84 85	0.0722125852545598	UP	1.79906242142523	0.0889753755366019	Cell cycle: SMC1B SMC3 STAG1 RAD21
hsa05152__126	0.0738598651640062	DOWN	-1.78876735749719	0.0908858458697889	Tuberculosis: NOS2
hsa05205__30	0.0738598651640062	DOWN	-1.78876735749719	0.0908858458697889	Proteoglycans in cancer: FLNA
hsa04550__66	0.0746949536830888	UP	1.78361982553317	0.091853284012123	Signaling pathways regulating pluripotency of stem cells: MYC
hsa04950__15	0.075115381238145	DOWN	-1.78104605955116	0.0923098766163992	Maturity onset diabetes of the young: IAPP
hsa04066__61	0.077246594006274	UP	1.76817722964111	0.0948049315073735	HIF-1 signaling pathway: HMOX1
hsa04921__11	0.077246594006274	UP	1.76817722964111	0.0948049315073735	Oxytocin signaling pathway: PRKACA
hsa04931__135	0.079426820330682	UP	1.75530839973106	0.0974170988259475	Insulin resistance: SREBF1**
hsa05205__103	0.0798688139027077	DOWN	-1.75273463374905	0.0978953041899463	Proteoglycans in cancer: CCND1
hsa04071__24	0.0812068004245492	DOWN	-1.74501333580301	0.0994055882721355	Sphingolipid signaling pathway: PTEN
hsa04630__36	0.0812068004245492	DOWN	-1.74501333580301	0.0994055882721355	Jak-STAT signaling pathway: GFAP
hsa04662__36	0.0816568180951722	UP	1.742439569821	0.0998263898508969	B cell receptor signaling pathway: CD79A
hsa04950__11	0.0816568180951722	UP	1.742439569821	0.0998263898508969	Maturity onset diabetes of the young: HNF4G
hsa04068__39	0.0848638752534511	UP	1.72442320794693	0.103679597920179	FoxO signaling pathway: CCNB3
hsa05160__55	0.0853302324735495	UP	1.72184944196492	0.104181615866017	Hepatitis C: MAPK14
hsa04068__46	0.0886530261062527	UP	1.70383308009085	0.108168205229642	FoxO signaling pathway: PLK4
hsa04668__120	0.09059810082223	UP	1.69353801616281	0.110469715408806	TNF signaling pathway: DNM1L
hsa04742__37	0.0915831358259201	UP	1.68839048419879	0.111598386651689	Taste transduction: P2RY4
hsa05020__46	0.0920793185057493	DOWN	-1.68581671821678	0.112130291297669	Prion diseases: PRKACA
hsa04014__55	0.0925773589082173	DOWN	-1.68324295223477	0.112663767738692	Ras signaling pathway: MLLT4
hsa04950__5	0.0935799277684375	DOWN	-1.67809542027075	0.11381015163553	Maturity onset diabetes of the young: GCK
hsa04071__48	0.0945908253696103	DOWN	-1.67294788830673	0.114965175206661	Sphingolipid signaling pathway: SMPD1
hsa05200__96	0.0951000918459401	UP	1.67037412232471	0.115509419895618	Pathways in cancer: C00416
hsa04919__91	0.0966399737543017	DOWN	-1.66265282437868	0.117303947470499	Thyroid hormone signaling pathway: PFKP
hsa04024__123	0.0976775964324333	DOWN	-1.65750529241466	0.118486897157225	cAMP signaling pathway: PAK1
hsa04012__29	0.100310625750254	DOWN	-1.64463646250461	0.121602365022404	ErbB signaling pathway: STAT5A*
hsa04360__3	0.104091577190556	DOWN	-1.62662010063054	0.126104496157998	Axon guidance: GNAI1
hsa05205__129	0.106860923397995	DOWN	-1.61375127072049	0.129292772095836	Proteoglycans in cancer: AKT3*
hsa05211__46	0.106860923397995	DOWN	-1.61375127072049	0.129292772095836	Renal cell carcinoma: AKT3
hsa04740__37	0.108550354885763	UP	1.60602997277446	0.131252327432657	Olfactory transduction: CNGB1*
hsa03320__38	0.109688334561359	UP	1.60088244081044	0.132543010058388	PPAR signaling pathway: SORBS1
hsa04740__16	0.110835722988378	DOWN	-1.59573490884641	0.133843395562444	Olfactory transduction: PRKG1
hsa05130__9	0.111412960218622	UP	1.5931611428644	0.134454047688369	Pathogenic Escherichia coli infection: TLR4
hsa04510__23 4 5	0.111992567304502	DOWN	-1.59058737688239	0.135066774046957	Focal adhesion: TLN1 ITGB1 ITGA11
hsa04024__109	0.113158914532722	UP	1.58543984491837	0.136385888651048	cAMP signaling pathway: BDNF
hsa04668__141	0.117316641302227	UP	1.5674234830443	0.141306390389028	TNF signaling pathway: JUN*
hsa04024__62	0.11852633023218	DOWN	-1.56227595108028	0.142671988793252	cAMP signaling pathway: BAD
hsa04360__96	0.119134831537538	UP	1.55970218509827	0.143312643059561	Axon guidance: GSK3B
hsa05152__120	0.119745778439385	DOWN	-1.55712841911626	0.143955417586439	Tuberculosis: TGFB1
hsa04931__35	0.12409136656348	UP	1.53911205724219	0.148988931484204	Insulin resistance: C00369
hsa05160__8	0.12409136656348	UP	1.53911205724219	0.148988931484204	Hepatitis C: NFKB1
hsa05110__50	0.125990810949215	DOWN	-1.53139075929616	0.151172882358604	Vibrio cholerae infection: ACTB
hsa04066__46	0.12662924577883	UP	1.52881699331415	0.151745122970932	HIF-1 signaling pathway: ENO1
hsa04360__111	0.12662924577883	DOWN	-1.52881699331415	0.151745122970932	Axon guidance: RHOA***
hsa04151__34	0.127913247510864	DOWN	-1.52366946135013	0.153186100747555	PI3K-Akt signaling pathway: GYS1
hsa05211__49	0.128559033666575	DOWN	-1.52109569536811	0.153861416725793	Renal cell carcinoma: TGFA*
hsa04015__27	0.129858204656948	UP	1.51594816340409	0.155317356174669	Rap1 signaling pathway: RALA
hsa04970__18	0.132487097974112	DOWN	-1.50565309947605	0.158360850568293	Salivary secretion: VAMP2
hsa05161__97	0.134485675628594	UP	1.49793180153002	0.160647542597665	Hepatitis B: BCL2
hsa04340__33	0.135830956843454	DOWN	-1.492784269566	0.161945664916783	Hedgehog signaling pathway: HHIP*
hsa04913__36	0.135830956843454	UP	1.492784269566	0.161945664916783	Ovarian steroidogenesis: CYP19A1
hsa04913__37	0.135830956843454	UP	1.492784269566	0.161945664916783	Ovarian steroidogenesis: CYP19A1*
hsa04750__40	0.13786833264262	DOWN	-1.48506297161997	0.164270511753635	Inflammatory mediator regulation of TRP channels: C00219
hsa04066__50	0.140621376707603	DOWN	-1.47476790769193	0.167444592416721	HIF-1 signaling pathway: TF
hsa05200__197	0.14201365744345	DOWN	-1.46962037572791	0.168995352967855	Pathways in cancer: CCND1**
hsa04022__57	0.14271375630492	UP	1.4670466097459	0.169613629409832	cGMP-PKG signaling pathway: C00144
hsa05132__48	0.14271375630492	DOWN	-1.4670466097459	0.169613629409832	Salmonella infection: KLC3
hsa04152__15	0.144829950941347	DOWN	-1.45932531179987	0.171911230460386	AMPK signaling pathway: FOXO1
hsa05133__60	0.144829950941347	UP	1.45932531179987	0.171911230460386	Pertussis: C5
hsa04910__32	0.14554066621592	DOWN	-1.45675154581786	0.172536852883101	Insulin signaling pathway: EIF4E
hsa05169__29	0.14554066621592	UP	1.45675154581786	0.172536852883101	Epstein-Barr virus infection: FCER2
hsa04611__34	0.149134357931599	UP	1.4438827159078	0.176685661130817	Platelet activation: C02198*
hsa05152__9	0.149861155992191	DOWN	-1.44130894992579	0.177434853250993	Tuberculosis: TCIRG1
hsa05200__188	0.150590652766274	DOWN	-1.43873518394378	0.178186295055308	Pathways in cancer: KLK3
hsa05160__85	0.152057763119915	UP	1.43358765197976	0.179809022594286	Hepatitis C: BAD
hsa05205__434	0.156524397542714	DOWN	-1.4181450560877	0.184974429548906	Proteoglycans in cancer: CASP3
hsa04611__92	0.158794698944834	DOWN	-1.41042375814167	0.187539433888965	Platelet activation: RHOA*
hsa04630__1	0.159556978673371	DOWN	-1.40784999215966	0.188321333497026	Jak-STAT signaling pathway: MYC
hsa04068__50	0.16108983680282	DOWN	-1.40270246019564	0.190011175990269	FoxO signaling pathway: TNFSF10
hsa04340__32	0.165755153860737	DOWN	-1.38725986430358	0.195391426665197	Hedgehog signaling pathway: PTCH1***
hsa04066__29	0.16733263653329	DOWN	-1.38211233233956	0.197003774464944	HIF-1 signaling pathway: LDHA
hsa04390__18	0.16733263653329	DOWN	-1.38211233233956	0.197003774464944	Hippo signaling pathway: MOB1A
hsa04064__54	0.172132750198613	UP	1.36666973644749	0.202528138774698	NF-kappa B signaling pathway: CCL13
hsa04012__40	0.175389588528415	UP	1.35637467251945	0.206230936698931	ErbB signaling pathway: ELK1*
hsa04950__22	0.176210935711104	UP	1.35380090653744	0.207067134584843	Maturity onset diabetes of the young: NR5A2
hsa05321__95	0.177862226990265	UP	1.34865337457342	0.208876952821692	Inflammatory bowel disease (IBD): SMAD2
hsa04340__40	0.17869218008188	UP	1.34607960859141	0.209589641931244	Hedgehog signaling pathway: SUFU
hsa05205__431	0.17869218008188	DOWN	-1.34607960859141	0.209589641931244	Proteoglycans in cancer: CDKN1A*
hsa04024__116	0.182040812684883	DOWN	-1.33578454466337	0.213251051767391	cAMP signaling pathway: ACOX1
hsa05010__50	0.182040812684883	DOWN	-1.33578454466337	0.213251051767391	Alzheimer's disease: ERN1
hsa04360__31	0.183732482740323	UP	1.33063701269935	0.215098651133374	Axon guidance: CDC42*
hsa03320__8	0.186291777723782	DOWN	-1.32291571475332	0.217959059989406	PPAR signaling pathway: GK
hsa05160__15 16	0.191489232392777	UP	1.30747311886126	0.223900602156832	Hepatitis C: TRAF6 RIPK1
hsa04728__71 72	0.193245207032831	UP	1.30232558689724	0.225813273640976	Dopaminergic synapse: CLOCK ARNTL
hsa04066__42	0.204029953283355	DOWN	-1.27144039511311	0.238119429949953	HIF-1 signaling pathway: HK1
hsa05213__13	0.204029953283355	DOWN	-1.27144039511311	0.238119429949953	Endometrial cancer: CASP9
hsa04261__37	0.209583721511007	DOWN	-1.25599779922105	0.244449294052875	Adrenergic signaling in cardiomyocytes: CREB3
hsa04933__21	0.211459085789262	UP	1.25085026725703	0.24648363659927	AGE-RAGE signaling pathway in diabetic complications: SMAD4
hsa04510__44	0.212401304248349	DOWN	-1.24827650127502	0.247428425717698	Focal adhesion: BCL2
hsa04921__46	0.213346551575625	DOWN	-1.24570273529301	0.248375570266791	Oxytocin signaling pathway: C00942*
hsa05160__53	0.218118341134694	UP	1.23283390538296	0.253616561257481	Hepatitis C: EIF2S1
hsa05162__74	0.218118341134694	UP	1.23283390538296	0.253616561257481	Measles: EIF2S1
hsa04350__12	0.224926999321065	UP	1.21481754350888	0.261371571876488	TGF-beta signaling pathway: ACVR2A
hsa04014__61	0.225911925562739	DOWN	-1.21224377752687	0.262191790075594	Ras signaling pathway: RAP1A
hsa04921__34 35	0.225911925562739	DOWN	-1.21224377752687	0.262191790075594	Oxytocin signaling pathway: MYL9 ACTB
hsa05200__211	0.229882405954346	DOWN	-1.20194871359883	0.266635210363096	Pathways in cancer: CXCL8
hsa04340__13	0.230882734833276	UP	1.19937494761682	0.26746526433522	Hedgehog signaling pathway: GLI1*
hsa04910__39	0.230882734833276	UP	1.19937494761682	0.26746526433522	Insulin signaling pathway: BAD
hsa04015__18	0.232892663579214	DOWN	-1.1942274156528	0.269627427520235	Rap1 signaling pathway: CDH1
hsa03320__10	0.233902269161368	UP	1.19165364967079	0.27062953433141	PPAR signaling pathway: PLIN1
hsa05142__36	0.23694968435652	DOWN	-1.18393235172476	0.273986742711323	Chagas disease (American trypanosomiasis): SMAD2
hsa05200__190	0.237971698051077	UP	1.18135858574275	0.274999274685101	Pathways in cancer: MYC*
hsa04540__1	0.242090608560711	UP	1.17106352181471	0.279072846270647	Gap junction: C00681
hsa05145__67	0.242090867174643	UP	1.17106352181471	0.279072846270647	Toxoplasmosis: BAD
hsa05205__17	0.242090867174643	UP	1.17106352181471	0.279072846270647	Proteoglycans in cancer: AKT3
hsa05218__14	0.242090867174643	UP	1.17106352181471	0.279072846270647	Melanoma: BAD
hsa04152__44	0.245212986274587	DOWN	-1.16334222386868	0.282498590564039	AMPK signaling pathway: SLC2A4
hsa04910__17	0.250479081801636	DOWN	-1.15047339395862	0.288388599696859	Insulin signaling pathway: C00031
hsa05168__10	0.255823633580342	DOWN	-1.13760456404857	0.29436167023727	Herpes simplex infection: FOS
hsa04340__31	0.260155946144134	UP	1.12730950012053	0.299163416649222	Hedgehog signaling pathway: GLI1***
hsa04920__16	0.26124691228743	DOWN	-1.12473573413852	0.300234219075279	Adipocytokine signaling pathway: POMC
hsa03320__59	0.267859114432047	UP	1.10929313824646	0.307645034240719	PPAR signaling pathway: NR1H3
hsa05166__53 146	0.268972232351299	UP	1.10671937226445	0.308734773725163	HTLV-I infection: CREB1 CRTC2
hsa04520__44 47	0.270088521737374	DOWN	-1.10414560628244	0.309826820723154	Adherens junction: ACTB TJP1
hsa05161__57	0.273456434713115	DOWN	-1.09642430833641	0.313498865665616	Hepatitis B: STAT3*
hsa04066__88	0.277991479884672	UP	1.08612924440837	0.318503652867865	HIF-1 signaling pathway: BCL2
hsa04670__28 41 49	0.281426184097913	UP	1.07840794646234	0.322046163166856	Leukocyte transendothelial migration: ACTB CTNNA1 CTNNB1
hsa04750__59	0.281426184097913	DOWN	-1.07840794646234	0.322046163166856	Inflammatory mediator regulation of TRP channels: TRPV2
hsa05161__29	0.283731920810406	UP	1.07326041449831	0.3244870841161	Hepatitis B: NFKB1
hsa04932__7	0.284889572939147	DOWN	-1.0706866485163	0.325612839143952	Non-alcoholic fatty liver disease (NAFLD): SREBF1
hsa04550__9	0.290725715024784	UP	1.05781781860625	0.332081227070863	Signaling pathways regulating pluripotency of stem cells: HNF1A
hsa04152__77	0.291902526759951	DOWN	-1.05524405262424	0.333222872285509	AMPK signaling pathway: CCND1
hsa04925__5	0.293082535092538	DOWN	-1.05267028664223	0.333961239198835	Aldosterone synthesis and secretion: KCNK3
hsa05016__55	0.293082535092538	UP	1.05267028664223	0.333961239198835	Huntington's disease: TGM2
hsa05205__140	0.293082535092538	UP	1.05267028664223	0.333961239198835	Proteoglycans in cancer: MAPK1***
hsa04010__120	0.297834550696098	UP	1.04237522271419	0.33917037621695	MAPK signaling pathway: NFATC1
hsa04911__24	0.306273815023639	UP	1.02435886084012	0.348569653803403	Insulin secretion: INS
hsa04014__65	0.316110928217349	UP	1.00376873298404	0.359547478281114	Ras signaling pathway: MLLT4*
hsa04670__54	0.317354991864113	UP	1.00119496700202	0.360744119608389	Leukocyte transendothelial migration: RAC1*
hsa04723__10	0.323623395341374	UP	0.988326137091973	0.367424990843772	Retrograde endocannabinoid signaling: CACNA1A
hsa04723__21	0.323623395341374	UP	0.988326137091973	0.367424990843772	Retrograde endocannabinoid signaling: CACNA1A*
hsa04068__51	0.324886692328507	DOWN	-0.985752371109963	0.368191854574949	FoxO signaling pathway: BCL6
hsa04068__56	0.324886692328507	DOWN	-0.985752371109963	0.368191854574949	FoxO signaling pathway: BCL6*
hsa05164__65 66	0.324886692328507	DOWN	-0.985752371109963	0.368191854574949	Influenza A: DNAJC3 HSPA1A
hsa05145__11	0.326153194293937	UP	0.983178605127952	0.369404371355218	Toxoplasmosis: MAPK14
hsa04530__20 31	0.327422900957774	DOWN	-0.980604839145942	0.370619054758829	Tight junction: ACTB MLLT4
hsa05215__46	0.328695811996908	DOWN	-0.978031073163932	0.371835900507038	Prostate cancer: MTOR
hsa04071__68	0.338994404704543	DOWN	-0.957440945307849	0.383255407003512	Sphingolipid signaling pathway: NFKB1
hsa04360__51	0.34290918622086	UP	0.949719647361818	0.387448202591098	Axon guidance: FYN
hsa04550__60	0.345535027358617	UP	0.944572115397797	0.39018047860988	Signaling pathways regulating pluripotency of stem cells: MAPK14
hsa05164__77	0.348173649482956	DOWN	-0.939424583433777	0.392923896323408	Influenza A: CASP9
hsa03320__39	0.350825044548876	DOWN	-0.934277051469756	0.395441067011001	PPAR signaling pathway: MMP1
hsa04550__34	0.350825044548876	UP	0.934277051469756	0.395441067011001	Signaling pathways regulating pluripotency of stem cells: MAPK1*
hsa05205__284	0.352155529224761	DOWN	-0.931703285487746	0.396702781422857	Proteoglycans in cancer: PRKCA*
hsa04151__100	0.354826067048466	UP	0.926555753523725	0.399471647683684	PI3K-Akt signaling pathway: PRKCA
hsa04261__39	0.356166117735372	DOWN	-0.923981987541714	0.400740200733392	Adrenergic signaling in cardiomyocytes: SCN1B
hsa04210__106	0.358855776167631	UP	0.918834455577694	0.403524837473955	Apoptosis: TUBA1B
hsa05133__94	0.361558168159497	DOWN	-0.913686923613673	0.406320453332353	Pertussis: IL12A
hsa04911__31	0.367001105454058	UP	0.903391859685632	0.41194449053057	Insulin secretion: CAMK2A
hsa04916__8	0.367001105454058	DOWN	-0.903391859685632	0.41194449053057	Melanogenesis: TYR*
hsa04933__24	0.368369779149366	UP	0.900818093703621	0.413233919415915	AGE-RAGE signaling pathway in diabetic complications: THBD
hsa04919__89	0.379433221810467	DOWN	-0.880227965847538	0.42513716385323	Thyroid hormone signaling pathway: CASP9
hsa04921__59	0.379433221810467	UP	0.880227965847538	0.42513716385323	Oxytocin signaling pathway: CCND1
hsa04151__102	0.380830380023199	DOWN	-0.877654199865528	0.426448321849577	PI3K-Akt signaling pathway: C8orf44-SGK3
hsa04024__76	0.385040775535436	UP	0.869932901919497	0.430649772161359	cAMP signaling pathway: C00416
hsa04919__45	0.385040775535436	DOWN	-0.869932901919497	0.430649772161359	Thyroid hormone signaling pathway: SLC9A1
hsa04110__96 97	0.390698700752504	DOWN	-0.859637837991456	0.436717940936321	Cell cycle: TFDP1 E2F4
hsa04014__76	0.392121034990085	UP	0.857064072009445	0.438047220419958	Ras signaling pathway: RALBP1*
hsa04071__11	0.393546505469593	UP	0.854490306027435	0.439378421733432	Sphingolipid signaling pathway: PRKCA
hsa04210__83	0.396406844914889	DOWN	-0.849342774063414	0.442309062704914	Apoptosis: TP53*
hsa04115__31	0.397841708642961	DOWN	-0.846769008081404	0.44338349379604	p53 signaling pathway: ADGRB1
hsa04710__7	0.397841708642961	UP	0.846769008081404	0.44338349379604	Circadian rhythm: PER1
hsa04510__47	0.400720810661244	DOWN	-0.841621476117383	0.446063035090331	Focal adhesion: CCND1
hsa05218__8	0.400720810661244	UP	0.841621476117383	0.446063035090331	Melanoma: CDK4
hsa03320__31	0.406516434650272	DOWN	-0.831326412189342	0.452246524989852	PPAR signaling pathway: CD36
hsa05161__44	0.407973119605708	UP	0.828752646207332	0.453598515821968	Hepatitis B: CXCL8
hsa04213__54	0.410895803279382	DOWN	-0.823605114243311	0.456577891402696	Longevity regulating pathway - multiple species: SOD2*
hsa04014__38	0.412361795810841	DOWN	-0.821031348261301	0.457936060477878	Ras signaling pathway: MAPK8
hsa04210__84	0.413830884601368	UP	0.81845758227929	0.458754119271959	Apoptosis: FAS**
hsa05200__203	0.413830884601368	DOWN	-0.81845758227929	0.458754119271959	Pathways in cancer: TGFA*
hsa05205__113	0.413830884601368	DOWN	-0.81845758227929	0.458754119271959	Proteoglycans in cancer: TP53
hsa04921__77	0.419738137383485	DOWN	-0.808162518351249	0.465028278386537	Oxytocin signaling pathway: KCNJ3
hsa04151__4	0.421222658322854	DOWN	-0.805588752369238	0.466397981725776	PI3K-Akt signaling pathway: RPS6
hsa04014__100	0.433209271354075	UP	0.784998624513156	0.479387644802301	Ras signaling pathway: REL
hsa04921__80	0.436236468987418	DOWN	-0.779851092549135	0.482453399192088	Oxytocin signaling pathway: KCNJ2
hsa04012__35	0.437754628426608	DOWN	-0.777277326567125	0.483563166851026	ErbB signaling pathway: CBLC
hsa04917__75	0.437754628426608	UP	0.777277326567125	0.483563166851026	Prolactin signaling pathway: CCND1**
hsa04115__25	0.443857576884476	DOWN	-0.766982262639083	0.490016678593379	p53 signaling pathway: CD82
hsa05200__216	0.448466498949089	DOWN	-0.759260964693052	0.494814181752988	Pathways in cancer: IL6
hsa04360__58	0.45000882385936	DOWN	-0.756687198711042	0.496224518797968	Axon guidance: PLXNC1
hsa04742__49	0.454653790119685	UP	0.748965900765011	0.500758775870392	Taste transduction: HTR1A
hsa05161__30	0.454653790119685	UP	0.748965900765011	0.500758775870392	Hepatitis B: MYC
hsa04370__37	0.457765382478545	UP	0.74381836880099	0.503890541111415	VEGF signaling pathway: CASP9
hsa04911__56	0.462455101608666	UP	0.736097070854959	0.508754763420775	Insulin secretion: CAMK2A*
hsa05205__270	0.465596413197076	UP	0.730949538890938	0.511910860384614	Proteoglycans in cancer: MAPK1****
hsa04213__71	0.467171504236565	UP	0.728375772908928	0.513342255240062	Longevity regulating pathway - multiple species: SIRT1**
hsa04390__74	0.475091114503814	DOWN	-0.715506942998876	0.521739453040717	Hippo signaling pathway: AXIN1
hsa05223__9	0.476683832268687	UP	0.712933177016866	0.523182780860317	Non-small cell lung cancer: BAD
hsa05216__14	0.478279469944616	DOWN	-0.710359411034856	0.524627626401596	Thyroid cancer: MAPK1*
hsa04390__76	0.479878022295368	DOWN	-0.707785645052845	0.526073981267792	Hippo signaling pathway: MYC
hsa03320__47	0.481479484036492	UP	0.705211879070835	0.52721442337096	PPAR signaling pathway: PLTP
hsa04725__50	0.481479484036492	DOWN	-0.705211879070835	0.52721442337096	Cholinergic synapse: BCL2
hsa04666__30 44	0.484691114311088	UP	0.700064347106814	0.53042201735034	Fc gamma R-mediated phagocytosis: C04637 GSN
hsa05169__11	0.485586981480301	DOWN	-0.622851367646504	0.531093095577116	Epstein-Barr virus infection: HLA-A
hsa04742__67	0.496022666497097	UP	0.682047985232742	0.542191152034931	Taste transduction: PRKACA
hsa04650__119	0.499286023395756	DOWN	-0.676900453268721	0.545440952302689	Natural killer cell mediated cytotoxicity: KLRC4-KLRK1
hsa04014__35	0.505846796269735	UP	0.66660538934068	0.552287118065562	Ras signaling pathway: NFKB1
hsa04066__30	0.512452660988573	UP	0.656310325412638	0.55917453542249	HIF-1 signaling pathway: PDK1
hsa04913__19	0.519103222553015	DOWN	-0.646015261484597	0.566102701785906	Ovarian steroidogenesis: STAR
hsa04670__45	0.524120231544788	DOWN	-0.638293963538566	0.571242410134952	Leukocyte transendothelial migration: PXN
hsa05169__79	0.530848025517489	DOWN	-0.627998899610525	0.578239675331804	Epstein-Barr virus infection: ATF2
hsa04921__23	0.532536795375768	UP	0.625425133628514	0.57974312775844	Oxytocin signaling pathway: C00219
hsa04014__41	0.534228280228544	UP	0.622851367646504	0.581247793022255	Ras signaling pathway: RAC1*
hsa04151__73	0.537619367438725	DOWN	-0.617703835682483	0.584598837625789	PI3K-Akt signaling pathway: MAPK1
hsa05161__195	0.539318955939542	DOWN	-0.615130069700473	0.586107760676923	Hepatitis B: IL6
hsa04115__27	0.541021231721808	DOWN	-0.612556303718462	0.586600631509104	p53 signaling pathway: THBS1
hsa04920__6	0.541021231721808	DOWN	-0.612556303718462	0.586600631509104	Adipocytokine signaling pathway: PTPN11
hsa04930__10	0.541021231721808	DOWN	-0.612556303718462	0.586600631509104	Type II diabetes mellitus: C00031
hsa04931__104	0.541021231721808	DOWN	-0.612556303718462	0.586600631509104	Insulin resistance: C00369*
hsa04921__58	0.542726187740358	DOWN	-0.609982537736452	0.58810986549258	Oxytocin signaling pathway: MEF2C
hsa04740__13	0.547857066063044	UP	0.602261239790421	0.59332762370747	Olfactory transduction: CNGA3
hsa04630__30	0.561655538085838	UP	0.581671111934338	0.607920942432771	Jak-STAT signaling pathway: CDKN1A
hsa04330__12	0.563392090514377	UP	0.579097345952328	0.609449475000872	Notch signaling pathway: HES1
hsa04931__137	0.573865407365885	DOWN	-0.563654750060266	0.620065037631109	Insulin resistance: MLXIP*
hsa05010__49	0.573865407365885	DOWN	-0.563654750060266	0.620065037631109	Alzheimer's disease: EIF2AK3
hsa04911__54	0.575619887708241	UP	0.561080984078256	0.621603315519417	Insulin secretion: RAB3A
hsa05152__15	0.580898474490595	DOWN	-0.553359686132225	0.626943270285944	Tuberculosis: CTSD
hsa04390__14	0.587971628387155	DOWN	-0.543064622204183	0.634212795487638	Hippo signaling pathway: AREG
hsa04014__67	0.589746119097676	UP	0.540490856222173	0.6357618805419	Ras signaling pathway: RAPGEF5*
hsa03320__41	0.59508434364223	UP	0.532769558276142	0.641148785380591	PPAR signaling pathway: ANGPTL4
hsa04930__7	0.596868641264394	DOWN	-0.530195792294131	0.642702680192433	Type II diabetes mellitus: C00002
hsa05211__31	0.59865536948172	UP	0.527622026312121	0.644257410799629	Renal cell carcinoma: SOS1
hsa05142__44	0.602236083494739	DOWN	-0.5224744943481	0.647369336891656	Chagas disease (American trypanosomiasis): PLCB1
hsa05205__121	0.602236083494739	DOWN	-0.5224744943481	0.647369336891656	Proteoglycans in cancer: PLAUR
hsa04012__3	0.613035662597033	UP	0.507031898456038	0.658601492292639	ErbB signaling pathway: ELK1
hsa05134__10	0.614843876613374	DOWN	-0.504458132474028	0.660166653803731	Legionellosis: NFKB1
hsa03320__32	0.616654433863992	DOWN	-0.501884366492018	0.661732542107619	PPAR signaling pathway: FABP3
hsa05215__22	0.619433643793983	DOWN	-0.476146706671914	0.66433551180873	Prostate cancer: C16038
hsa05032__13	0.620282542135309	UP	0.496736834527997	0.664487398330812	Morphine addiction: PRKACA
hsa05216__5	0.620282542135309	UP	0.496736834527997	0.664487398330812	Thyroid cancer: MAPK1
hsa04620__39	0.625742053106306	DOWN	-0.489015536581966	0.669954027228917	Toll-like receptor signaling pathway: IL6
hsa05142__53	0.62756647985525	DOWN	-0.486441770599956	0.67152472417313	Chagas disease (American trypanosomiasis): AKT3
hsa05210__40	0.634886889348006	DOWN	-0.476146706671914	0.678971237953844	Colorectal cancer: CASP9
hsa04068__41	0.636722620696477	UP	0.473572940689904	0.680547101415632	FoxO signaling pathway: CDKN2B
hsa04723__9	0.638560584830672	UP	0.470999174707893	0.680962167364831	Retrograde endocannabinoid signaling: PRKCA
hsa04725__20	0.638560584830672	UP	0.470999174707893	0.680962167364831	Cholinergic synapse: PRKCA
hsa04726__18	0.638560584830672	UP	0.470999174707893	0.680962167364831	Serotonergic synapse: PRKCA
hsa05200__195	0.638560584830672	UP	0.470999174707893	0.680962167364831	Pathways in cancer: BIRC8
hsa04071__66	0.640400772276377	UP	0.468425408725883	0.681377718633812	Sphingolipid signaling pathway: C01245
hsa04530__4 53	0.640400772276377	DOWN	-0.468425408725883	0.681377718633812	Tight junction: OCLN OCLN
hsa04530__4 45	0.640400772276377	DOWN	-0.468425408725883	0.681377718633812	Tight junction: OCLN TJP2
hsa04662__6	0.640400772276377	UP	0.468425408725883	0.681377718633812	B cell receptor signaling pathway: NFKB1
hsa05220__21	0.645934579127235	DOWN	-0.460704110779852	0.6868766690323	Chronic myeloid leukemia: NFKBIA
hsa04213__53	0.647783564260258	DOWN	-0.458130344797842	0.688064057232914	Longevity regulating pathway - multiple species: SOD1
hsa05211__22	0.647783564260258	DOWN	-0.458130344797842	0.688064057232914	Renal cell carcinoma: TGFA
hsa05145__9	0.651488050796337	DOWN	-0.452982812833821	0.691607936410348	Toxoplasmosis: MAPK1
hsa04022__63	0.655201160707585	UP	0.4478352808698	0.6947646619467	cGMP-PKG signaling pathway: C00575
hsa04722__35	0.655201160707585	DOWN	-0.4478352808698	0.6947646619467	Neurotrophin signaling pathway: FOXO3
hsa04724__26	0.664521145771233	DOWN	-0.434966450959749	0.703456469241773	Glutamatergic synapse: PRKACA
hsa04914__15	0.664521145771233	UP	0.434966450959749	0.703456469241773	Progesterone-mediated oocyte maturation: ANAPC10
hsa05205__189	0.664521145771233	DOWN	-0.434966450959749	0.703456469241773	Proteoglycans in cancer: IL12B
hsa04360__20	0.666391442122452	UP	0.432392684977738	0.705039144002301	Axon guidance: ROCK1
hsa05321__55	0.668263814840452	UP	0.429818918995728	0.706622233024878	Inflammatory bowel disease (IBD): IL4*
hsa05205__77	0.673893177365349	DOWN	-0.422097621049697	0.712173948408037	Proteoglycans in cancer: MIR21
hsa03320__53	0.687099498668659	UP	0.404081259175624	0.72572229229815	PPAR signaling pathway: ADIPOQ
hsa04014__66	0.690890525147839	UP	0.398933727211604	0.729316458849882	Ras signaling pathway: RAF1*
hsa04916__9	0.696591602934265	UP	0.391212429265573	0.734921741669559	Melanogenesis: PRKACA
hsa04550__17	0.702309870913274	DOWN	-0.383491131319542	0.74053885939733	Signaling pathways regulating pluripotency of stem cells: AKT3
hsa04024__101	0.715717712008071	UP	0.365474769445469	0.753830482546617	cAMP signaling pathway: HCN4
hsa04920__1	0.715717712008071	UP	0.365474769445469	0.753830482546617	Adipocytokine signaling pathway: C00195
hsa05152__82	0.719564900697926	DOWN	-0.360327237481449	0.757457954292102	Tuberculosis: IL6
hsa05222__40	0.721491169411138	UP	0.357753471499438	0.759060418434226	Small cell lung cancer: TRAF1
hsa05152__90	0.723419157655827	UP	0.355179705517428	0.760662897165808	Tuberculosis: CR1
hsa04015__3	0.725348999939482	UP	0.352605939535417	0.762265531815596	Rap1 signaling pathway: MAPK1
hsa05161__207	0.73308551973961	UP	0.342310875607376	0.769535023235043	Hepatitis B: CDK2
hsa05161__219	0.73308551973961	UP	0.342310875607376	0.769535023235043	Hepatitis B: CDK2*
hsa05168__79	0.735023929528194	DOWN	-0.339737109625366	0.771139008142645	Herpes simplex infection: EIF2S1
hsa04024__91	0.738905805516676	UP	0.334589577661345	0.774779022637184	cAMP signaling pathway: GRIA1
hsa04933__59	0.742794347288354	DOWN	-0.329442045697324	0.77842196238417	AGE-RAGE signaling pathway in diabetic complications: SERPINE1
hsa04380__51	0.744741089186343	DOWN	-0.326868279715314	0.780027038228059	Osteoclast differentiation: FOS*
hsa05132__68	0.752544261078402	DOWN	-0.316573215787273	0.787760817028589	Salmonella infection: NOS2
hsa04360__131	0.760372802157595	DOWN	-0.306278151859231	0.794627639184717	Axon guidance: RAC1****
hsa04971__52 53	0.760372802157595	UP	0.306278151859231	0.794627639184717	Gastric acid secretion: EZR ACTB
hsa05140__16	0.760372802157595	UP	0.306278151859231	0.794627639184717	Leishmaniasis: STAT1
hsa04014__79	0.770193010772675	DOWN	-0.29340932194918	0.804442838933772	Ras signaling pathway: RAC1**
hsa04919__18	0.772161538512859	UP	0.290835555967169	0.80560329309587	Thyroid hormone signaling pathway: STAT1
hsa05217__3	0.772161538512859	UP	0.290835555967169	0.80560329309587	Basal cell carcinoma: GLI1
hsa05200__173	0.774131533805958	UP	0.288261789985159	0.806762702174928	Pathways in cancer: CCNA1
hsa05221__16	0.774131533805958	UP	0.288261789985159	0.806762702174928	Acute myeloid leukemia: CCNA1
hsa05223__7	0.776102984686583	UP	0.285688024003148	0.808368906998941	Non-small cell lung cancer: FOXO3
hsa04662__16	0.778075879161212	DOWN	-0.283114258021138	0.809974834871977	B cell receptor signaling pathway: VAV3
hsa04722__33	0.782025950779041	UP	0.277966726057117	0.813636080572435	Neurotrophin signaling pathway: BAD
hsa04062__59	0.784003103796498	DOWN	-0.275392960075107	0.81524174434622	Chemokine signaling pathway: FOXO3
hsa04921__53	0.789942886356223	UP	0.267671662129076	0.820963873596982	Oxytocin signaling pathway: RGS2
hsa05032__4	0.791925547853096	DOWN	-0.265097896147066	0.822569433065764	Morphine addiction: ADCY1
hsa05161__26	0.795894898588167	DOWN	-0.259950364183045	0.826235643340976	Hepatitis B: MMP9
hsa04213__52	0.799869537936928	DOWN	-0.254802832219024	0.829903291984256	Longevity regulating pathway - multiple species: SOD2
hsa05215__34	0.805841197731116	DOWN	-0.247081534272993	0.835637754159364	Prostate cancer: BAD
hsa04722__85	0.815819007283032	DOWN	-0.234212704362942	0.845517879031891	Neurotrophin signaling pathway: BAX
hsa04540__12	0.81781821363188	UP	0.231638938380931	0.846655880669037	Gap junction: C00025
hsa05010__37	0.81781821363188	DOWN	-0.231638938380931	0.846655880669037	Alzheimer's disease: MAPT
hsa04810__26 80	0.82582676960289	UP	0.22134387445289	0.854476046301668	Regulation of actin cytoskeleton: PFN3 ACTB
hsa05222__19	0.831845150852456	DOWN	-0.213622576506859	0.859756346783149	Small cell lung cancer: CASP9
hsa05222__39	0.831845150852456	DOWN	-0.213622576506859	0.859756346783149	Small cell lung cancer: BCL2L1
hsa05020__24	0.837873231709258	DOWN	-0.205901278560828	0.864085511735288	Prion diseases: PRNP*
hsa05020__26	0.837873231709258	DOWN	-0.205901278560828	0.864085511735288	Prion diseases: PRNP**
hsa05020__25 8	0.837873231709258	DOWN	-0.205901278560828	0.864085511735288	Prion diseases: PRNP PRNP*
hsa05020__10 34	0.837873231709258	DOWN	-0.205901278560828	0.864085511735288	Prion diseases: PRNP PRNP***
hsa04971__56	0.839884961275519	DOWN	-0.203327512578817	0.865685047853374	Gastric acid secretion: CAMK2A
hsa04211__23	0.841897561516076	DOWN	-0.200753746596807	0.867283727022317	Longevity regulating pathway - mammal: SOD2
hsa04068__57	0.845925849668675	DOWN	-0.195606214632786	0.870479009598817	FoxO signaling pathway: IL7R
hsa04550__53 64	0.845925849668675	DOWN	-0.195606214632786	0.870479009598817	Signaling pathways regulating pluripotency of stem cells: SMAD1 SMAD4
hsa04914__23	0.849958169183784	UP	0.190458682668766	0.874149644168763	Progesterone-mediated oocyte maturation: PRKACA
hsa05014__53	0.862078285213859	DOWN	-0.175016086776704	0.886129703455602	Amyotrophic lateral sclerosis (ALS): RAB5A
hsa05160__54	0.866125697977651	UP	0.169868554812683	0.889803273100058	Hepatitis C: IRF1
hsa04024__112	0.868150728543812	UP	0.167294788830673	0.891396294499356	cAMP signaling pathway: GLI1
hsa05152__94	0.872203372850468	DOWN	-0.162147256866652	0.895068343848186	Tuberculosis: CAMP
hsa04115__30	0.87828860115705	UP	0.154425958920621	0.900821114396342	p53 signaling pathway: SERPINE1
hsa04919__102	0.890480301423737	UP	0.138983363028559	0.912329599986478	Thyroid hormone signaling pathway: BMP4
hsa05216__11	0.890480301423737	DOWN	-0.138983363028559	0.912329599986478	Thyroid cancer: MYC
hsa05205__158	0.894550109566863	DOWN	-0.133835831064538	0.915999812466559	Proteoglycans in cancer: PDCD4
hsa04550__69	0.896586061928089	UP	0.131262065082528	0.917085035581317	Signaling pathways regulating pluripotency of stem cells: ID1
hsa04933__61	0.896586061928089	UP	0.131262065082528	0.917085035581317	AGE-RAGE signaling pathway in diabetic complications: MMP2
hsa04920__5	0.908815616298145	DOWN	-0.115819469190466	0.929088434724818	Adipocytokine signaling pathway: NFKBIA
hsa04742__46	0.921066747533952	UP	0.100376873298404	0.940078519248386	Taste transduction: P2RY1
hsa04728__32	0.921066819550973	UP	0.100376873298404	0.940078519248386	Dopaminergic synapse: CREB3
hsa05133__30	0.921066819550973	DOWN	-0.100376873298404	0.940078519248386	Pertussis: NOS2
hsa04360__35	0.923110588932726	UP	0.0978031073163932	0.941652984041581	Axon guidance: ROCK1*
hsa04911__4	0.927199637544897	DOWN	-0.0926555753523725	0.945310970671113	Insulin secretion: CACNA1C
hsa05020__59	0.939477894801142	DOWN	-0.0772129794603104	0.957309633585328	Prion diseases: CCL5
hsa04740__39	0.94562260719979	UP	0.0694916815142794	0.962527020004554	Olfactory transduction: PRKG1*
hsa04921__56	0.94562260719979	UP	0.0694916815142794	0.962527020004554	Oxytocin signaling pathway: JUN
hsa04916__10	0.95177055642184	DOWN	-0.0617703835682483	0.968260354908845	Melanogenesis: CAMK2A
hsa04064__129	0.95382052905115	UP	0.059196617586238	0.969820765198653	NF-kappa B signaling pathway: PTGS2
hsa05010__61	0.955870807243498	DOWN	-0.0566228516042276	0.971379798166865	Alzheimer's disease: GAPDH
hsa04727__26	0.972282407338899	DOWN	-0.0360327237481449	0.985924794058171	GABAergic synapse: KCNJ6
hsa05032__81	0.972282407338899	DOWN	-0.0360327237481449	0.985924794058171	Morphine addiction: KCNJ6
hsa05032__91	0.972282407338899	DOWN	-0.0360327237481449	0.985924794058171	Morphine addiction: KCNJ6**
hsa05032__85	0.972282407338899	DOWN	-0.0360327237481449	0.985924794058171	Morphine addiction: KCNJ6*
hsa05213__31	0.976387414111629	UP	0.0308851917841242	0.989553371691344	Endometrial cancer: MYC
hsa05161__45	0.978440158845314	UP	0.0283114258021138	0.990565225468936	Hepatitis B: PCNA
hsa05215__8	0.978440158845314	DOWN	-0.0283114258021138	0.990565225468936	Prostate cancer: NFKBIA
hsa03320__55	0.986652429701398	DOWN	-0.0180163618740724	0.998341365325217	PPAR signaling pathway: SCD
hsa04727__49	0.988705750360944	DOWN	-0.0154425958920621	0.99988057315835	GABAergic synapse: GABRR3
hsa04152__33	1	0	0	1	AMPK signaling pathway: CPT1C
hsa04152__41	1	0	0	1	AMPK signaling pathway: FBP1
hsa04211__2	1	0	0	1	Longevity regulating pathway - mammal: RPS6KB1
hsa04911__41	1	0	0	1	Insulin secretion: ABCC8
hsa04911__35	1	0	0	1	Insulin secretion: TRPM4
hsa04922__67	1	0	0	1	Glucagon signaling pathway: FBP1
hsa04922__60	1	0	0	1	Glucagon signaling pathway: CPT1C*
hsa04924__34	1	0	0	1	Renin secretion: REN
hsa04924__47	1	0	0	1	Renin secretion: KCNMA1
hsa04931__151	1	0	0	1	Insulin resistance: CPT1A
hsa04931__29	1	0	0	1	Insulin resistance: CPT1B
hsa04960__15	1	0	0	1	Aldosterone-regulated sodium reabsorption: C00762
hsa05030__13	1	0	0	1	Cocaine addiction: SLC6A3
hsa05031__15	1	0	0	1	Amphetamine addiction: MAOA
hsa05031__77	1	0	0	1	Amphetamine addiction: MAOA*
hsa05034__7	1	0	0	1	Alcoholism: GRIN3A
hsa05034__75	1	0	0	1	Alcoholism: SLC29A1
hsa05140__37	1	0	0	1	Leishmaniasis: ELK1
hsa05140__55	1	0	0	1	Leishmaniasis: JUN
hsa05140__41 57	1	0	0	1	Leishmaniasis: NOS2 CYBA
hsa05211__12	1	0	0	1	Renal cell carcinoma: EGLN2