5 activation 7 3 activation 4 4 activation 6 6 activation 9 8 activation 9 25 activation 3 33 activation 25 19 activation.up 23 19 activation.down 23 19 activation 23 23 activation.up 42 26 activation.up 19 26 activation.down 19 26 activation 19 58 activation.up 19 58 activation.down 19 58 activation 19 23 activation.up 73 23 inhibition 10 23 inhibition.down 46 20 activation.up 24 20 activation.down 24 20 activation 24 24 inhibition.down 65 27 activation.up 20 27 activation.down 20 27 activation 20 61 activation.up 20 61 activation.down 20 61 activation 20 65 activation.down 66 66 activation.down 67 24 inhibition 21 24 activation.up 68 24 activation.up 50 33 activation.down 40 7 activation 7_func 9 activation 9_func 42 activation 42_func 73 activation 73_func 10 activation 10_func 46 activation 46_func 21 activation 21_func 68 activation 68_func 50 activation 50_func 40 activation 40_func 67 activation 67_func