p.value	UP.DOWN	statistic	FDRp.value	path.name
hsa05169__11	9.33549858430584e-40	DOWN	-12.1449578014911	1.75414018399107e-36	Epstein-Barr virus infection: HLA-A
hsa04211__43 59 60 61	6.1284355906948e-34	UP	12.1449578014911	2.88257613646128e-31	Longevity regulating pathway - mammal: ULK3 RB1CC1 ATG13 ATG101
hsa04750__8	6.1284355906948e-34	DOWN	-12.1449578014911	2.88257613646128e-31	Inflammatory mediator regulation of TRP channels: ASIC2
hsa04530__11 24 23	6.13640476096069e-34	DOWN	-12.1449578014911	2.88257613646128e-31	Tight junction: TJP1 YBX3 CDK4
hsa04970__18	1.36379234779177e-33	DOWN	-12.0794611107281	4.31981496935329e-31	Salivary secretion: VAMP2
hsa04261__36	1.37939807430121e-33	DOWN	-12.0785254437172	4.31981496935329e-31	Adrenergic signaling in cardiomyocytes: MAPK1
hsa04261__72	2.17287398909143e-33	DOWN	-12.0410987632811	4.94464032714788e-31	Adrenergic signaling in cardiomyocytes: ATP2B1
hsa05110__51	2.27312920896559e-33	UP	12.0373560952375	4.94464032714788e-31	Vibrio cholerae infection: PDIA4
hsa04261__73	2.40632269582313e-33	DOWN	-12.032677760183	4.94464032714788e-31	Adrenergic signaling in cardiomyocytes: KCNE1
hsa04261__39	2.69501807581345e-33	DOWN	-12.023321090074	4.94464032714788e-31	Adrenergic signaling in cardiomyocytes: SCN1B
hsa04670__15	3.01792502019412e-33	DOWN	-12.013964419965	4.94464032714788e-31	Leukocyte transendothelial migration: PECAM1
hsa04261__34	3.15783309876395e-33	DOWN	-12.0102217519214	4.94464032714788e-31	Adrenergic signaling in cardiomyocytes: AKT3
hsa04261__4	3.69949663935465e-33	DOWN	-11.9971224137688	5.13646858276581e-31	Adrenergic signaling in cardiomyocytes: SLC8A1
hsa03320__40	3.82706546879836e-33	DOWN	-11.9943154127361	5.13646858276581e-31	PPAR signaling pathway: FABP4
hsa04933__24	4.23657852917701e-33	DOWN	-11.985894409638	5.30702070421573e-31	AGE-RAGE signaling pathway in diabetic complications: THBD
hsa04261__20	5.6168378735395e-33	DOWN	-11.9625027343655	6.59627397773795e-31	Adrenergic signaling in cardiomyocytes: ATP1B4
hsa04261__23	8.80974900777629e-33	DOWN	-11.9250760539295	8.91034327162168e-31	Adrenergic signaling in cardiomyocytes: SLC9A1
hsa04933__35	8.90927952067508e-33	DOWN	-11.9241403869186	8.91034327162168e-31	AGE-RAGE signaling pathway in diabetic complications: CCND1
hsa04933__56	9.00992667167705e-33	DOWN	-11.9232047199077	8.91034327162168e-31	AGE-RAGE signaling pathway in diabetic complications: NFATC1
hsa04261__52	1.11517818804773e-32	DOWN	-11.9054270467005	1.04185371042626e-30	Adrenergic signaling in cardiomyocytes: MAPK14
hsa04066__56	1.19279364064383e-32	DOWN	-11.8998130446351	1.04185371042626e-30	HIF-1 signaling pathway: TEK
hsa03460__25 40	1.21983936292591e-32	UP	11.8979417106133	1.04185371042626e-30	Fanconi anemia pathway: MLH1 PMS2
hsa04933__62	1.44306023253002e-32	DOWN	-11.8839067054498	1.17891746822779e-30	AGE-RAGE signaling pathway in diabetic complications: AGER**
hsa03320__38	1.97373957421613e-32	DOWN	-11.8577080291446	1.54527360831338e-30	PPAR signaling pathway: SORBS1
hsa03320__31	2.82073357703e-32	DOWN	-11.8277666847958	2.1078208517343e-30	PPAR signaling pathway: CD36
hsa04211__56	2.9166227857952e-32	DOWN	-11.8249596837631	2.1078208517343e-30	Longevity regulating pathway - mammal: CAT
hsa04022__39	3.11821790700998e-32	DOWN	-11.8193456816977	2.17004868417472e-30	cGMP-PKG signaling pathway: KCNJ8
hsa04922__17	3.60371071307596e-32	DOWN	-11.807182010556	2.41834729638205e-30	Glucagon signaling pathway: PKM
hsa05120__20	4.40208670808031e-32	UP	11.7903400043598	2.85224859464927e-30	Epithelial cell signaling in Helicobacter pylori infection: CXCL8
hsa04933__19	5.68238335028911e-32	DOWN	-11.768819663109	3.55906610506441e-30	AGE-RAGE signaling pathway in diabetic complications: TGFBR2
hsa03320__23	6.1409352174043e-32	DOWN	-11.7622699940327	3.72219912048474e-30	PPAR signaling pathway: ACADL
hsa04540__14 31	7.49578214500782e-32	DOWN	-11.7454279878365	4.40142957827178e-30	Gap junction: GJA1 TJP1
hsa04213__62	8.01033324710925e-32	DOWN	-11.7398139857711	4.56103520342978e-30	Longevity regulating pathway - multiple species: CAT*
hsa04916__10	8.94697915803782e-32	DOWN	-11.7304573156621	4.85663727714732e-30	Melanogenesis: CAMK2A
hsa04022__44	9.04642387973158e-32	DOWN	-11.7295216486512	4.85663727714732e-30	cGMP-PKG signaling pathway: BAD
hsa04014__76	9.77394552952796e-32	DOWN	-11.7229719795749	4.99567957553227e-30	Ras signaling pathway: RALBP1*
hsa04022__46	9.99227806165965e-32	DOWN	-11.7211006455531	4.99567957553227e-30	cGMP-PKG signaling pathway: VASP
hsa04670__18	1.01030241548817e-31	DOWN	-11.7201649785422	4.99567957553227e-30	Leukocyte transendothelial migration: CDH5
hsa04540__14 16	1.34599594478693e-31	DOWN	-11.6958376362588	6.32281595063659e-30	Gap junction: GJA1 GJA1
hsa04540__14 15	1.34599594478693e-31	DOWN	-11.6958376362588	6.32281595063659e-30	Gap junction: GJA1 GJA1*
hsa04925__18	1.40665514216617e-31	DOWN	-11.6920949682152	6.44659759056155e-30	Aldosterone synthesis and secretion: PDE2A
hsa04933__29	1.45392360967069e-31	DOWN	-11.6892879671825	6.50457729183625e-30	AGE-RAGE signaling pathway in diabetic complications: ICAM1
hsa03460__28	1.65929426865549e-31	UP	11.6780599630517	7.25073007163643e-30	Fanconi anemia pathway: RAD51C
hsa04923__66	1.85225199158329e-31	DOWN	-11.6687032929427	7.90995793678409e-30	Regulation of lipolysis in adipocytes: LIPE
hsa04114__80	2.00042036466388e-31	UP	11.6621536238664	8.35286636711873e-30	Oocyte meiosis: CDC25C*
hsa04213__60	2.13674788766903e-31	DOWN	-11.656539621801	8.72815061071762e-30	Longevity regulating pathway - multiple species: CAT
hsa04022__57	2.33296467650803e-31	DOWN	-11.6490542857137	9.32689495140126e-30	cGMP-PKG signaling pathway: C00144
hsa04621__33 35	2.63227749908094e-31	DOWN	-11.6387619485938	1.03042696266106e-29	NOD-like receptor signaling pathway: NLRC4 PYCARD
hsa04068__59	2.84228944135376e-31	DOWN	-11.6322122795175	1.08993099189872e-29	FoxO signaling pathway: S1PR1
hsa04068__52	3.46183308124704e-31	DOWN	-11.6153702733213	1.28948649514329e-29	FoxO signaling pathway: CAT
hsa04920__43	3.49993673508822e-31	DOWN	-11.6144346063104	1.28948649514329e-29	Adipocytokine signaling pathway: C00162
hsa04152__87	3.65655996988247e-31	DOWN	-11.6106919382668	1.31480436356355e-29	AMPK signaling pathway: CD36
hsa04022__43	3.7785756057707e-31	DOWN	-11.6078849372341	1.31480436356355e-29	cGMP-PKG signaling pathway: MAPK1
hsa04933__22	3.7785756057707e-31	DOWN	-11.6078849372341	1.31480436356355e-29	AGE-RAGE signaling pathway in diabetic complications: EDN1
hsa04916__9	3.86215624681327e-31	DOWN	-11.6060136032123	1.31945301595675e-29	Melanogenesis: PRKACA
hsa04910__46	4.80578147553746e-31	DOWN	-11.5873002629943	1.61251132009552e-29	Insulin signaling pathway: FBP1
hsa04261__66	5.13115138300379e-31	DOWN	-11.5816862609289	1.69147955239721e-29	Adrenergic signaling in cardiomyocytes: C01245
hsa04723__40	6.96314727337951e-31	DOWN	-11.5554875846237	2.18062562111335e-29	Retrograde endocannabinoid signaling: GRIA1
hsa04724__4	6.96314727337951e-31	DOWN	-11.5554875846237	2.18062562111335e-29	Glutamatergic synapse: GRIA1
hsa05031__12	6.96314727337951e-31	DOWN	-11.5554875846237	2.18062562111335e-29	Amphetamine addiction: GRIA1
hsa05031__55	7.19439336090562e-31	DOWN	-11.552680583591	2.21610903690847e-29	Amphetamine addiction: GRIA1*
hsa05200__205	8.37843144496756e-31	UP	11.5395812454384	2.53920527178936e-29	Pathways in cancer: SLC2A1
hsa04921__46	1.11135002967562e-30	DOWN	-11.5152539031549	3.3146455646992e-29	Oxytocin signaling pathway: C00942*
hsa03320__29	1.22535065471556e-30	DOWN	-11.5068329000568	3.59755293782898e-29	PPAR signaling pathway: OLR1
hsa04923__16	1.36567141400834e-30	DOWN	-11.4974762299478	3.94784090295643e-29	Regulation of lipolysis in adipocytes: PLIN1
hsa04022__48	1.52192869250417e-30	DOWN	-11.4881195598388	4.26821494509751e-29	cGMP-PKG signaling pathway: SLC8A2
hsa04110__59 15 16 17 18 19 20	1.52192869250417e-30	UP	11.4881195598388	4.26821494509751e-29	Cell cycle: CDC45 MCM7 MCM6 MCM5 MCM4 MCM3 MCM2
hsa04933__12	1.75186399461954e-30	DOWN	-11.4759558886971	4.84081242042665e-29	AGE-RAGE signaling pathway in diabetic complications: EGR1
hsa04115__43 57	1.80964226802442e-30	UP	11.4731488876644	4.92799684292447e-29	p53 signaling pathway: CDK1 CCNB3
hsa04540__22	1.86920994028495e-30	DOWN	-11.4703418866317	5.01749353970774e-29	Gap junction: C00547
hsa05200__189	2.06028898319538e-30	UP	11.4619208835336	5.45251126679453e-29	Pathways in cancer: BIRC5
hsa04520__1 13	2.24623341703227e-30	DOWN	-11.4544355474464	5.86204526472726e-29	Adherens junction: SMAD4 SMAD2
hsa05211__4	2.37081044484089e-30	UP	11.4497572123919	6.10240113130964e-29	Renal cell carcinoma: SLC2A1
hsa04014__67	2.94150956540124e-30	DOWN	-11.4310438721739	7.46904928836341e-29	Ras signaling pathway: RAPGEF5*
hsa05166__64	3.00558700829932e-30	UP	11.4291725381521	7.52999731812589e-29	HTLV-I infection: CCNB2
hsa04933__65	3.4946228464607e-30	DOWN	-11.4160731999995	8.6399951690785e-29	AGE-RAGE signaling pathway in diabetic complications: COL1A1
hsa04115__11 12	3.68777899860565e-30	UP	11.411394864945	8.99913862127275e-29	p53 signaling pathway: CDK2 CCNE1
hsa04933__78	4.28682248386456e-30	DOWN	-11.3982955267924	1.01774456511808e-28	AGE-RAGE signaling pathway in diabetic complications: TGFB1
hsa04022__50	4.33313279454212e-30	DOWN	-11.3973598597815	1.01774456511808e-28	cGMP-PKG signaling pathway: ATP2B1
hsa05200__168	4.33313279454212e-30	UP	11.3973598597815	1.01774456511808e-28	Pathways in cancer: E2F1
hsa05210__21	6.44461741095888e-30	UP	11.3627401803781	1.49499211298663e-28	Colorectal cancer: BIRC5
hsa04014__62	6.8723366280152e-30	DOWN	-11.3571261783127	1.5747707956147e-28	Ras signaling pathway: RASSF5
hsa04530__6 11 45	9.5736076676564e-30	DOWN	-11.3281205009748	2.16732636235258e-28	Tight junction: CLDN24 TJP1 TJP2
hsa04730__20	1.16012659256942e-29	DOWN	-11.3112784947786	2.59205753764758e-28	Long-term depression: C00025
hsa04014__66	1.17256461256011e-29	DOWN	-11.3103428277677	2.59205753764758e-28	Ras signaling pathway: RAF1*
hsa03460__7	1.26341499355774e-29	UP	11.3037931586914	2.72868594585632e-28	Fanconi anemia pathway: FANCI
hsa04933__57	1.26341499355774e-29	DOWN	-11.3037931586914	2.72868594585632e-28	AGE-RAGE signaling pathway in diabetic complications: FIGF
hsa03320__55	1.30445782334872e-29	DOWN	-11.3009861576587	2.78531392053664e-28	PPAR signaling pathway: SCD
hsa04933__25	1.39055407851593e-29	DOWN	-11.2953721555933	2.93578776801284e-28	AGE-RAGE signaling pathway in diabetic complications: IL1A
hsa05164__36	1.42048770188786e-29	DOWN	-11.2935008215715	2.9656626576081e-28	Influenza A: IL33
hsa03320__60	1.68414661698514e-29	DOWN	-11.2785301493971	3.47748515748909e-28	PPAR signaling pathway: CYP27A1
hsa04725__61	1.73873479882631e-29	DOWN	-11.2757231483644	3.55030789687498e-28	Cholinergic synapse: FOS
hsa04014__69	1.77609868177886e-29	DOWN	-11.2738518143426	3.55030789687498e-28	Ras signaling pathway: PLCE1*
hsa04914__11	1.77609868177886e-29	UP	11.2738518143426	3.55030789687498e-28	Progesterone-mediated oocyte maturation: CDK1
hsa04970__32	1.83364340379682e-29	DOWN	-11.2710448133099	3.62675363761497e-28	Salivary secretion: RYR3
hsa04012__8	1.853233129556e-29	DOWN	-11.270109146299	3.62731776087055e-28	ErbB signaling pathway: STAT5A
hsa04925__3	2.12761473325562e-29	DOWN	-11.2579454751573	4.12143101421372e-28	Aldosterone synthesis and secretion: ITPR1
hsa04340__15	2.92432477290904e-29	DOWN	-11.2298754648302	5.60694515132254e-28	Hedgehog signaling pathway: HHIP
hsa04933__23	3.11609991053545e-29	DOWN	-11.2242614627648	5.91429467868295e-28	AGE-RAGE signaling pathway in diabetic complications: F3
hsa03320__30	3.69068533280797e-29	DOWN	-11.2092907905904	6.93479774034618e-28	PPAR signaling pathway: LPL
hsa04022__71	3.76952981487853e-29	UP	11.2074194565686	7.01281833876906e-28	cGMP-PKG signaling pathway: PPIF
hsa04022__65	3.93226685291724e-29	DOWN	-11.203676788525	7.24385236924656e-28	cGMP-PKG signaling pathway: PDE2A
hsa04261__3	4.37024786587905e-29	DOWN	-11.194320118416	7.97252013590945e-28	Adrenergic signaling in cardiomyocytes: RYR2
hsa04115__38	4.96011754184303e-29	UP	11.1830921142852	8.96159698184908e-28	p53 signaling pathway: GTSE1
hsa04110__43 83 84 85	6.12370688003827e-29	DOWN	-11.1643787740672	1.09585192643732e-27	Cell cycle: SMC1B SMC3 STAG1 RAD21
hsa04630__24	6.80329044550605e-29	UP	11.1550221039582	1.20597950444395e-27	Jak-STAT signaling pathway: MCL1
hsa04730__30	7.63748753096428e-29	DOWN	-11.1447297668383	1.32878139543351e-27	Long-term depression: C00025*
hsa04919__28	7.63748753096428e-29	DOWN	-11.1447297668383	1.32878139543351e-27	Thyroid hormone signaling pathway: RCAN1
hsa05133__46	8.04939926885009e-29	DOWN	-11.1400514317838	1.38759827763021e-27	Pertussis: CFL1
hsa04024__118	8.30718422177828e-29	DOWN	-11.1372444307511	1.41901810479285e-27	cAMP signaling pathway: MYL9
hsa05211__42	8.39489096337581e-29	UP	11.1363087637402	1.42108109190839e-27	Renal cell carcinoma: SLC2A1*
hsa04380__68	8.84739650478385e-29	DOWN	-11.1316304286857	1.48430875290079e-27	Osteoclast differentiation: TGFBR1
hsa05034__99	1.1379580903445e-28	DOWN	-11.109174420424	1.89223296615692e-27	Alcoholism: PDYN
hsa04666__41	1.19914580869418e-28	UP	11.1044960853695	1.97648681976874e-27	Fc gamma R-mediated phagocytosis: MARCKS
hsa04066__51	1.7291313718054e-28	DOWN	-11.071747739988	2.8252503022803e-27	HIF-1 signaling pathway: TFRC
hsa05145__29	1.86017988575647e-28	DOWN	-11.0651980709117	3.01317069425552e-27	Toxoplasmosis: C06314
hsa03460__48	2.08639646086404e-28	UP	11.0549057337918	3.35071705125088e-27	Fanconi anemia pathway: RAD51
hsa04530__20 22	2.94186184867076e-28	DOWN	-11.0240287224321	4.68454102851895e-27	Tight junction: ACTB MYL12B
hsa05169__30	4.05909797239112e-28	DOWN	-10.9950230450942	6.40928158833859e-27	Epstein-Barr virus infection: FGR
hsa04330__11	4.36464318155517e-28	DOWN	-10.9884733760179	6.83430378178514e-27	Notch signaling pathway: PTCRA
hsa04022__49	4.45605804195678e-28	DOWN	-10.9866020419961	6.91977938912132e-27	cGMP-PKG signaling pathway: ATP1B4
hsa04014__64	5.48136590271242e-28	DOWN	-10.967888701778	8.44220207475134e-27	Ras signaling pathway: PIK3R5*
hsa04713__60	5.6541389058621e-28	DOWN	-10.9650817007453	8.6375016293617e-27	Circadian entrainment: PER1
hsa04914__30	5.71282246358674e-28	UP	10.9641460337344	8.65676887828991e-27	Progesterone-mediated oocyte maturation: CDK1*
hsa05132__54	5.89293203850447e-28	DOWN	-10.9613390327017	8.85825544027991e-27	Salmonella infection: IL1B
hsa04630__36	6.07856676392236e-28	UP	10.958532031669	9.06478329318263e-27	Jak-STAT signaling pathway: GFAP
hsa05010__59	6.67098706370246e-28	DOWN	-10.9501110285709	9.86990920684797e-27	Alzheimer's disease: LRP1
hsa05160__55	7.70826364144019e-28	UP	10.9370116904183	1.13154901423954e-26	Hepatitis C: MAPK14
hsa05169__45	7.86895682748506e-28	DOWN	-10.9351403563965	1.14618371153833e-26	Epstein-Barr virus infection: RB1
hsa04022__3	7.95054496336951e-28	DOWN	-10.9342046893856	1.14915953739779e-26	cGMP-PKG signaling pathway: MYL9
hsa04713__61	8.81400936176495e-28	DOWN	-10.9248480192766	1.26423844204247e-26	Circadian entrainment: FOS
hsa05132__55	9.87152418612343e-28	DOWN	-10.9145556821567	1.40519651103984e-26	Salmonella infection: IL18
hsa04550__34	1.06090465789775e-27	DOWN	-10.9080060130804	1.49882695653373e-26	Signaling pathways regulating pluripotency of stem cells: MAPK1*
hsa04024__114	1.20026469439552e-27	DOWN	-10.8967780089496	1.6830577319173e-26	cAMP signaling pathway: HHIP
hsa04024__9 95	1.73681352834024e-27	DOWN	-10.8630939965572	2.41738712574171e-26	cAMP signaling pathway: ATP1B4 FXYD1
hsa04068__57	1.77277738914389e-27	DOWN	-10.8612226625354	2.44930052514806e-26	FoxO signaling pathway: IL7R
hsa04068__41	1.82811238650538e-27	DOWN	-10.8584156615027	2.50731618557928e-26	FoxO signaling pathway: CDKN2B
hsa04152__61	1.94397234877974e-27	UP	10.8528016594372	2.64690148069358e-26	AMPK signaling pathway: RPS6KB1
hsa04630__31	1.9639780448256e-27	UP	10.8518659924263	2.65490269512756e-26	Jak-STAT signaling pathway: BCL2L1
hsa04961__5	2.02522836640514e-27	DOWN	-10.8490589913936	2.71814578605375e-26	Endocrine and other factor-regulated calcium reabsorption: TRPV5
hsa04261__15 17	2.06711052448398e-27	DOWN	-10.8471876573718	2.75468133014567e-26	Adrenergic signaling in cardiomyocytes: ACTC1 MYH6
hsa04066__55	2.15346870793331e-27	DOWN	-10.8434449893282	2.84955471986387e-26	HIF-1 signaling pathway: ANGPT1
hsa04066__58	2.17561146801429e-27	DOWN	-10.8425093223173	2.85872304083835e-26	HIF-1 signaling pathway: EDN1
hsa04962__22	2.24340352809442e-27	DOWN	-10.8397023212846	2.92733002033987e-26	Vasopressin-regulated water reabsorption: ARHGDIA
hsa04390__13	2.45960411481422e-27	UP	10.8312813181865	3.18730767705926e-26	Hippo signaling pathway: BIRC5
hsa05217__19	2.51038641691543e-27	DOWN	-10.8294099841647	3.23083292971513e-26	Basal cell carcinoma: HHIP
hsa04540__16 17	2.66905560581782e-27	DOWN	-10.8237959820993	3.41167039682427e-26	Gap junction: GJA1 GJA1**
hsa05200__214	3.34069865219932e-27	DOWN	-10.8032113078595	4.24133295100171e-26	Pathways in cancer: CSF3R
hsa05014__49	3.40948663977297e-27	DOWN	-10.8013399738377	4.28613332878082e-26	Amyotrophic lateral sclerosis (ALS): C00001
hsa04022__51	3.4444179491533e-27	DOWN	-10.8004043068268	4.28613332878082e-26	cGMP-PKG signaling pathway: GTF2I
hsa04810__35 81 80	3.4444179491533e-27	DOWN	-10.8004043068268	4.28613332878082e-26	Regulation of actin cytoskeleton: MYL12B MYH9 ACTB
hsa05205__158	3.58769311062101e-27	DOWN	-10.7966616387832	4.43504957556374e-26	Proteoglycans in cancer: PDCD4
hsa04530__11 13	5.61191313637174e-27	DOWN	-10.7554922903036	6.89201619819771e-26	Tight junction: TJP1 EPB41
hsa04510__19 23	6.14841674576359e-27	DOWN	-10.7470712872055	7.50186692551285e-26	Focal adhesion: VCL TLN1
hsa04933__30	6.60059220145422e-27	DOWN	-10.7405216181292	8.00162112679514e-26	AGE-RAGE signaling pathway in diabetic complications: CXCL8
hsa04924__31	8.08201334047696e-27	DOWN	-10.7218082779112	9.73468145304885e-26	Renin secretion: C02135
hsa04068__58	9.31140695659228e-27	DOWN	-10.7087089397585	1.11440341856286e-25	FoxO signaling pathway: KLF2
hsa05168__106 134	9.59797453166011e-27	UP	10.7059019387258	1.14143000917654e-25	Herpes simplex infection: SRSF8 C1QBP
hsa04915__66	9.695426852298e-27	DOWN	-10.7049662717149	1.14576773933761e-25	Estrogen signaling pathway: AKT3*
hsa04530__11 36 14	9.89328419656279e-27	DOWN	-10.7030949376931	1.16184256283384e-25	Tight junction: TJP1 CTNNB1 CTNNA1
hsa04933__26	1.00951442135347e-26	DOWN	-10.7012236036713	1.17818484330632e-25	AGE-RAGE signaling pathway in diabetic complications: IL6
hsa04114__56	1.12805896659696e-26	DOWN	-10.6909312665514	1.30840913471339e-25	Oocyte meiosis: REC8
hsa03460__27	1.15104960756728e-26	UP	10.6890599325296	1.32688479301774e-25	Fanconi anemia pathway: BRCA1
hsa04022__45	1.31223565448017e-26	DOWN	-10.6768962613879	1.5034699968099e-25	cGMP-PKG signaling pathway: CREB3
hsa05205__337	1.68767972726528e-26	DOWN	-10.6535045861154	1.92190921668573e-25	Proteoglycans in cancer: CTNNB1**
hsa04750__53	1.72195623671111e-26	UP	10.6516332520936	1.94912998119287e-25	Inflammatory mediator regulation of TRP channels: TRPM8
hsa04066__89	1.73935240587281e-26	DOWN	-10.6506975850827	1.9570318387036e-25	HIF-1 signaling pathway: CDKN1A
hsa04630__27	1.84744917692815e-26	UP	10.6450835830173	2.0662839306238e-25	Jak-STAT signaling pathway: PIM1
hsa04620__20	2.02220149551353e-26	UP	10.6366625799192	2.24835302371002e-25	Toll-like receptor signaling pathway: IFNB1*
hsa04611__43	2.39819026664091e-26	DOWN	-10.6207562407339	2.65070559471663e-25	Platelet activation: MYL12B
hsa04550__69	2.73176685697884e-26	DOWN	-10.6085925695922	3.00174849372119e-25	Signaling pathways regulating pluripotency of stem cells: ID1
hsa04920__31	2.98925681786497e-26	DOWN	-10.6001715664941	3.26558927951644e-25	Adipocytokine signaling pathway: AGRP
hsa04933__52	3.01931180705952e-26	DOWN	-10.5992358994832	3.27935658119354e-25	AGE-RAGE signaling pathway in diabetic complications: FOXO1
hsa04510__19 26	3.0496663318647e-26	DOWN	-10.5983002324723	3.2932891020539e-25	Focal adhesion: VCL ACTN4
hsa04933__61	3.43839081592986e-26	DOWN	-10.5870722283414	3.69184933893269e-25	AGE-RAGE signaling pathway in diabetic complications: MMP2
hsa04914__39	3.54301086431863e-26	DOWN	-10.5842652273087	3.78256671253108e-25	Progesterone-mediated oocyte maturation: PIK3R5
hsa04014__68	3.65078566930385e-26	DOWN	-10.581458226276	3.87560806362821e-25	Ras signaling pathway: RALGDS*
hsa04920__12	4.03397603966762e-26	DOWN	-10.572101556167	4.25833762839071e-25	Adipocytokine signaling pathway: C00165
hsa05231__38	4.11535989133067e-26	UP	10.5702302221452	4.31997834402812e-25	Choline metabolism in cancer: RPS6KB1
hsa05020__62	4.7792344592249e-26	DOWN	-10.5561952169817	4.98898974937977e-25	Prion diseases: NOTCH1
hsa05166__132 136	4.97352321244773e-26	UP	10.5524525489381	5.16312161115431e-25	HTLV-I infection: CREBBP TP53
hsa04530__11 62	6.83743984498709e-26	DOWN	-10.5225112045893	7.05909311468722e-25	Tight junction: TJP1 SHROOM1
hsa05166__60	7.18549992037731e-26	UP	10.5178328695348	7.37789855212511e-25	HTLV-I infection: POLD3
hsa05205__256	8.2562830235415e-26	DOWN	-10.5047335313822	8.43128032675787e-25	Proteoglycans in cancer: ACTB
hsa04723__42	1.15607719833447e-25	DOWN	-10.4729208530116	1.16788658907015e-24	Retrograde endocannabinoid signaling: KCNJ3
hsa04723__50	1.15607719833447e-25	DOWN	-10.4729208530116	1.16788658907015e-24	Retrograde endocannabinoid signaling: KCNJ3*
hsa05142__21	1.2027031690054e-25	DOWN	-10.469178184968	1.20849157997923e-24	Chagas disease (American trypanosomiasis): TICAM1
hsa04630__28	1.38105709287108e-25	UP	10.4560788468154	1.38032248803445e-24	Jak-STAT signaling pathway: CCND1
hsa04924__23	1.46529846227898e-25	DOWN	-10.4504648447499	1.45677027017048e-24	Renin secretion: ITPR1
hsa04270__48	1.58559013525978e-25	DOWN	-10.4429795086627	1.56806519165954e-24	Vascular smooth muscle contraction: KCNMB2*
hsa04024__91	1.66569012714792e-25	DOWN	-10.4383011736082	1.63865536592196e-24	cAMP signaling pathway: GRIA1
hsa04750__62	1.87463110669617e-25	UP	10.4270731694774	1.83459992160527e-24	Inflammatory mediator regulation of TRP channels: TRPM8*
hsa04550__60	1.91193559145317e-25	UP	10.4252018354556	1.86141294110907e-24	Signaling pathways regulating pluripotency of stem cells: MAPK14
hsa04066__44	2.32748348946913e-25	DOWN	-10.4064884952376	2.25429973026417e-24	HIF-1 signaling pathway: GAPDH
hsa05031__97	2.44464831835732e-25	DOWN	-10.4018101601831	2.35563804625303e-24	Amphetamine addiction: ARC
hsa04152__78	2.69679348448886e-25	UP	10.3924534900741	2.58534436599723e-24	AMPK signaling pathway: CCNA2
hsa05205__415	3.12409315232977e-25	DOWN	-10.3784184849106	2.97978225036936e-24	Proteoglycans in cancer: MAPK1******
hsa04916__15	3.41200017003901e-25	DOWN	-10.3699974818125	3.23795369671884e-24	Melanogenesis: MITF*
hsa04261__15 16	3.44556983312489e-25	DOWN	-10.3690618148016	3.25337975700587e-24	Adrenergic signaling in cardiomyocytes: ACTC1 TPM1
hsa04066__45	3.6183907529519e-25	DOWN	-10.3643834797471	3.39947811239831e-24	HIF-1 signaling pathway: ALDOA
hsa05166__65	3.83714595334578e-25	UP	10.3587694776817	3.58706330663518e-24	HTLV-I infection: PTTG2
hsa04664__23	4.62004480426997e-25	DOWN	-10.3409918044746	4.29755652832836e-24	Fc epsilon RI signaling pathway: AKT3
hsa04742__46	5.04397091169238e-25	DOWN	-10.3325708013765	4.66877898673398e-24	Taste transduction: P2RY1
hsa04390__58	6.691350941045e-25	DOWN	-10.3054364580603	6.16325902854096e-24	Hippo signaling pathway: SMAD7
hsa04919__100	7.02489910721214e-25	DOWN	-10.3007581230058	6.43891971826907e-24	Thyroid hormone signaling pathway: CTNNB1*
hsa04933__58	7.51970946868079e-25	DOWN	-10.2942084539295	6.85899713186952e-24	AGE-RAGE signaling pathway in diabetic complications: CCL2
hsa05010__47	7.66732128083562e-25	DOWN	-10.2923371199077	6.95985347183098e-24	Alzheimer's disease: C00533
hsa04919__49	9.31063239410345e-25	DOWN	-10.2736237796897	8.41090301371172e-24	Thyroid hormone signaling pathway: ACTB
hsa04068__50	9.40156091851682e-25	DOWN	-10.2726881126788	8.4524081176522e-24	FoxO signaling pathway: TNFSF10
hsa04931__61	9.58573087080102e-25	DOWN	-10.270816778657	8.57694681249291e-24	Insulin resistance: ACACB
hsa05205__17	9.77347466429524e-25	DOWN	-10.2689454446352	8.70348762758804e-24	Proteoglycans in cancer: AKT3
hsa04066__42	1.174896311233e-24	DOWN	-10.2511677714281	1.04133498528623e-23	HIF-1 signaling pathway: HK1
hsa04919__21 53	1.18632503659587e-24	DOWN	-10.2502321044172	1.04652804871532e-23	Thyroid hormone signaling pathway: THRA C02465
hsa04270__10 3 71	1.24514182865471e-24	DOWN	-10.2455537693627	1.09328107291691e-23	Vascular smooth muscle contraction: ACTA2 MYL9 MYH11
hsa04530__11 43	1.51072402301085e-24	DOWN	-10.2268404291447	1.32030252987786e-23	Tight junction: TJP1 ACTN4
hsa04022__66	1.54018708539623e-24	UP	10.2249690951229	1.3398201543794e-23	cGMP-PKG signaling pathway: PDE3A
hsa04024__109	1.6478618787472e-24	DOWN	-10.2184194260466	1.42688132265714e-23	cAMP signaling pathway: BDNF
hsa04062__44	1.79732229144435e-24	DOWN	-10.2099984229485	1.54915990166236e-23	Chemokine signaling pathway: MAPK1
hsa04151__4	1.9414045057361e-24	UP	10.2025130868613	1.66570733620006e-23	PI3K-Akt signaling pathway: RPS6
hsa03320__61	2.01767878375539e-24	DOWN	-10.1987704188177	1.72328110667108e-23	PPAR signaling pathway: APOA1
hsa04066__37	2.15836809221788e-24	DOWN	-10.1922207497414	1.8351011969581e-23	HIF-1 signaling pathway: PDHA1
hsa04923__26 27	2.20024028681104e-24	DOWN	-10.1903494157196	1.86227544996304e-23	Regulation of lipolysis in adipocytes: PNPLA2 ABHD5
hsa04066__61	2.2866641194958e-24	DOWN	-10.1866067476759	1.926745237907e-23	HIF-1 signaling pathway: HMOX1
hsa04931__149	2.3310861191369e-24	DOWN	-10.1847354136541	1.95540661511528e-23	Insulin resistance: ACACB*
hsa04728__70 73	2.46954588386153e-24	DOWN	-10.1791214115887	2.06234520701148e-23	Dopaminergic synapse: KIF5A GRIA1
hsa04530__1 5	2.56634724520806e-24	DOWN	-10.1753787435451	2.1337019795336e-23	Tight junction: IGSF5 IGSF5
hsa04970__27	2.85236249223115e-24	DOWN	-10.1650864064252	2.36105247704949e-23	Salivary secretion: PRKCA
hsa04910__26	2.8798788006173e-24	UP	10.1641507394143	2.37337380103505e-23	Insulin signaling pathway: RPS6
hsa05161__213	2.99259826211425e-24	UP	10.1604080713707	2.45549874869549e-23	Hepatitis B: E2F1
hsa04917__75	3.26244613516737e-24	UP	10.1519870682726	2.6652766469476e-23	Prolactin signaling pathway: CCND1**
hsa04727__35	3.35764579131581e-24	DOWN	-10.1491800672399	2.73117594886684e-23	GABAergic synapse: PRKACA
hsa04110__60 10 11 12 13 14 9	3.55637677979688e-24	DOWN	-10.1435660651745	2.88035860743032e-23	Cell cycle: CDC6 ORC3 ORC5 ORC4 ORC2 ORC1 ORC6
hsa05142__7	4.21300698747301e-24	DOWN	-10.1257883919674	3.3975279525587e-23	Chagas disease (American trypanosomiasis): C1QA
hsa04740__21	5.16417519652619e-24	DOWN	-10.1070750517494	4.14678854456099e-23	Olfactory transduction: PDE1A
hsa04068__67	6.07343070189285e-24	DOWN	-10.0911687125641	4.85616012291773e-23	FoxO signaling pathway: GABARAP
hsa04933__27	6.93994582853672e-24	DOWN	-10.0780693744115	5.52549076772055e-23	AGE-RAGE signaling pathway in diabetic complications: TNF
hsa04914__34	7.14098847838278e-24	DOWN	-10.0752623733788	5.66156850248154e-23	Progesterone-mediated oocyte maturation: MAPK14
hsa04960__3	7.7057414049824e-24	DOWN	-10.0677770372916	6.08365046216888e-23	Aldosterone-regulated sodium reabsorption: SCNN1A
hsa03320__9	8.39409202273738e-24	DOWN	-10.0593560341935	6.59937192917303e-23	PPAR signaling pathway: PCK1
hsa04022__37 38	8.47423792632455e-24	DOWN	-10.0584203671826	6.63462210981826e-23	cGMP-PKG signaling pathway: ATP2A1 PLN
hsa04068__43	8.97127784399245e-24	DOWN	-10.0528063651171	6.99461870077253e-23	FoxO signaling pathway: CDKN1A
hsa04742__54	1.0948657908651e-23	DOWN	-10.0331573578882	8.46606099191574e-23	Taste transduction: P2RX2*
hsa04742__40	1.0948657908651e-23	DOWN	-10.0331573578882	8.46606099191574e-23	Taste transduction: P2RX2
hsa04725__18	1.1589853620478e-23	DOWN	-10.0275433558228	8.92513727576975e-23	Cholinergic synapse: ITPR1
hsa04666__20	1.23842265939123e-23	DOWN	-10.0209936867465	9.49794357957599e-23	Fc gamma R-mediated phagocytosis: PLA2G4B
hsa04068__42	1.29844197599193e-23	DOWN	-10.016315351692	9.91777428003592e-23	FoxO signaling pathway: CDKN2D
hsa04950__11	1.3107870691776e-23	UP	10.0153796846811	9.97153402018102e-23	Maturity onset diabetes of the young: HNF4G
hsa05205__270	1.37427772314449e-23	DOWN	-10.0107013496266	1.04123703297923e-22	Proteoglycans in cancer: MAPK1****
hsa04623__9	1.66015937918646e-23	UP	9.9919880094086	1.25278693714512e-22	Cytosolic DNA-sensing pathway: IKBKE
hsa04970__39	1.72403059033878e-23	UP	9.988245341365	1.29578139169863e-22	Salivary secretion: KCNN4
hsa04933__21	1.80731773012487e-23	DOWN	-9.9835670063105	1.35296813342814e-22	AGE-RAGE signaling pathway in diabetic complications: SMAD4
hsa04068__47	1.84173428202129e-23	DOWN	-9.9816956722887	1.36783348455257e-22	FoxO signaling pathway: GADD45G
hsa04068__54	1.84173428202129e-23	DOWN	-9.9816956722887	1.36783348455257e-22	FoxO signaling pathway: GADD45G*
hsa04933__63	1.91252613613344e-23	DOWN	-9.97795300424509	1.41481756291131e-22	AGE-RAGE signaling pathway in diabetic complications: SELE
hsa05211__45	1.96738216251252e-23	DOWN	-9.97514600321239	1.44969062092589e-22	Renal cell carcinoma: ETS1
hsa04630__7	1.98601150405346e-23	UP	9.97421033620149	1.45770141254549e-22	Jak-STAT signaling pathway: BCL2
hsa04650__110 111	2.04295401532144e-23	DOWN	-9.97140333516879	1.49366171003462e-22	Natural killer cell mediated cytotoxicity: ITGAL ITGB2
hsa05030__77	2.16173316668269e-23	DOWN	-9.96578933310338	1.57437853495999e-22	Cocaine addiction: BDNF
hsa03320__53	2.26592035908897e-23	DOWN	-9.96111099804888	1.6438858512464e-22	PPAR signaling pathway: ADIPOQ
hsa04620__21	2.46613880184753e-23	UP	9.95268999495077	1.78225954179673e-22	Toll-like receptor signaling pathway: IFNA1
hsa04068__45	2.7347694289594e-23	DOWN	-9.94239765783087	1.96882442797499e-22	FoxO signaling pathway: RBL2
hsa04923__52 53	2.92059781108811e-23	DOWN	-9.93584798875456	2.08661721940478e-22	Regulation of lipolysis in adipocytes: PNPLA2 ABHD5*
hsa05166__62 63	2.92059781108811e-23	UP	9.93584798875456	2.08661721940478e-22	HTLV-I infection: ANAPC10 CDC20
hsa04728__64	3.06093464755517e-23	DOWN	-9.93116965370006	2.17859704649855e-22	Dopaminergic synapse: SCN1A
hsa04015__96	3.20794522996326e-23	DOWN	-9.92649131864555	2.27461474984942e-22	Rap1 signaling pathway: PLCE1
hsa04068__13	3.33056931583361e-23	DOWN	-9.92274865060195	2.35268411445539e-22	FoxO signaling pathway: PCK1
hsa04970__21	3.83316981981915e-23	DOWN	-9.90871364543844	2.69757531514614e-22	Salivary secretion: ITPR1
hsa04360__108	3.90562255100434e-23	DOWN	-9.90684231141664	2.7383077512452e-22	Axon guidance: CFL1
hsa04110__10 11 12 13 14 9 15 16 17 18 19 20	4.05462011121784e-23	UP	9.90309964337304	2.82171525517715e-22	Cell cycle: ORC3 ORC5 ORC4 ORC2 ORC1 ORC6 MCM7 MCM6 MCM5 MCM4 MCM3 MCM2
hsa04550__53 64	4.05462011121784e-23	DOWN	-9.90309964337304	2.82171525517715e-22	Signaling pathways regulating pluripotency of stem cells: SMAD1 SMAD4
hsa04024__31	4.66520936017813e-23	DOWN	-9.88906463820953	3.22276778962306e-22	cAMP signaling pathway: C00165
hsa04024__32	4.66520936017813e-23	DOWN	-9.88906463820953	3.22276778962306e-22	cAMP signaling pathway: C01245
hsa05110__52	4.70900903606295e-23	DOWN	-9.88812897119863	3.24110914972977e-22	Vibrio cholerae infection: ADCY3
hsa04750__40	5.02721754498687e-23	DOWN	-9.88157930212232	3.44749699526655e-22	Inflammatory mediator regulation of TRP channels: C00219
hsa05134__6	5.51905175189223e-23	DOWN	-9.87222263201331	3.77101754247473e-22	Legionellosis: IL1B
hsa04020__64	5.94657342865766e-23	DOWN	-9.86473729592611	4.03379475539629e-22	Calcium signaling pathway: C01330*
hsa04020__12	5.94657342865766e-23	DOWN	-9.86473729592611	4.03379475539629e-22	Calcium signaling pathway: C01330
hsa04066__46	6.00226798376083e-23	DOWN	-9.86380162891521	4.04238764927835e-22	HIF-1 signaling pathway: ENO1
hsa04360__40 139	6.00226798376083e-23	DOWN	-9.86380162891521	4.04238764927835e-22	Axon guidance: UNC5D DCC
hsa04151__105 62	6.52733342886974e-23	UP	9.8553806258171	4.38030696887366e-22	PI3K-Akt signaling pathway: CCND1 CDK2
hsa04020__42	9.64482816562728e-23	DOWN	-9.81608261135927	6.449335275165e-22	Calcium signaling pathway: MYLK4
hsa04152__64	1.08803370643893e-22	DOWN	-9.80391894021756	7.24969976737146e-22	AMPK signaling pathway: ACACB
hsa04925__5	1.12911085201478e-22	DOWN	-9.80017627217396	7.49681728245859e-22	Aldosterone synthesis and secretion: KCNK3
hsa04360__145	1.43615813374283e-22	DOWN	-9.77584892989054	9.46856538000974e-22	Axon guidance: ABLIM3
hsa04630__1	1.43615813374283e-22	UP	9.77584892989054	9.46856538000974e-22	Jak-STAT signaling pathway: MYC
hsa04014__30	1.44948955661224e-22	DOWN	-9.77491326287964	9.52304502403638e-22	Ras signaling pathway: C01245
hsa04530__13 45 20	1.71151861973826e-22	DOWN	-9.75807125668343	1.1205378001701e-21	Tight junction: EPB41 TJP2 ACTB
hsa05166__136 139	1.75953344455004e-22	UP	9.75526425565073	1.14797338274636e-21	HTLV-I infection: TP53 TBPL2
hsa04530__11 33	2.21512507571618e-22	DOWN	-9.73187258037821	1.44021453884799e-21	Tight junction: TJP1 CGN
hsa05200__209	2.51939285879625e-22	DOWN	-9.7187732422256	1.63239282126833e-21	Pathways in cancer: FIGF**
hsa05016__52	2.63779752793089e-22	UP	9.71409490717109	1.70323764776019e-21	Huntington's disease: CASP3
hsa04650__116	2.66213110727695e-22	DOWN	-9.71315924016019	1.71306313375801e-21	Natural killer cell mediated cytotoxicity: FCGR3A
hsa05205__284	2.83879991649866e-22	DOWN	-9.70660957108389	1.82051366658737e-21	Proteoglycans in cancer: PRKCA*
hsa04919__43	3.56981870843083e-22	DOWN	-9.68321789581137	2.28152699086447e-21	Thyroid hormone signaling pathway: TBC1D4
hsa05160__53	3.98408010378577e-22	UP	9.67198989168056	2.52908328209915e-21	Hepatitis C: EIF2S1
hsa05162__74	3.98408010378577e-22	UP	9.67198989168056	2.52908328209915e-21	Measles: EIF2S1
hsa04015__63	4.78274748922639e-22	DOWN	-9.65327655146255	3.02585270446343e-21	Rap1 signaling pathway: GNAI1
hsa04550__36	5.00600497014124e-22	DOWN	-9.64859821640805	3.15647091909241e-21	Signaling pathways regulating pluripotency of stem cells: AKT3*
hsa04068__44	5.53411996072118e-22	DOWN	-9.63830587928814	3.47779645692144e-21	FoxO signaling pathway: CDKN1B
hsa04913__21	5.68748058108021e-22	DOWN	-9.63549887825544	3.55042392420256e-21	Ovarian steroidogenesis: CYP17A1
hsa04913__22	5.68748058108021e-22	DOWN	-9.63549887825544	3.55042392420256e-21	Ovarian steroidogenesis: CYP17A1*
hsa05120__50	5.84504551752444e-22	DOWN	-9.63269187722273	3.63670216140014e-21	Epithelial cell signaling in Helicobacter pylori infection: EGFR
hsa05219__27	6.06186959456221e-22	DOWN	-9.62894920917913	3.75915939543974e-21	Bladder cancer: RPS6KA5
hsa04530__5 11 31	6.88532731342463e-22	DOWN	-9.61584987102652	4.25576645458055e-21	Tight junction: IGSF5 TJP1 MLLT4
hsa04917__31	7.2712608421842e-22	DOWN	-9.61023586896112	4.47957348277512e-21	Prolactin signaling pathway: GALT
hsa04725__54	7.54036357459437e-22	DOWN	-9.60649320091751	4.63017750217739e-21	Cholinergic synapse: CHRM1*
hsa04020__22	1.00792204402744e-21	DOWN	-9.57655185656869	6.16900821083898e-21	Calcium signaling pathway: C00575
hsa04664__3 4 5	1.24104114649522e-21	DOWN	-9.55503151531797	7.57115686449517e-21	Fc epsilon RI signaling pathway: FCER1G MS4A2 FCER1A
hsa05211__41	1.29839901792782e-21	DOWN	-9.55035318026347	7.89544257180055e-21	Renal cell carcinoma: PDGFB*
hsa04068__53	1.47327434443117e-21	DOWN	-9.53725384211086	8.90122988162756e-21	FoxO signaling pathway: SOD2
hsa04670__73	1.47327434443117e-21	DOWN	-9.53725384211086	8.90122988162756e-21	Leukocyte transendothelial migration: MYL12B*
hsa05200__216	1.52738590706653e-21	DOWN	-9.53351117406726	9.19858371595513e-21	Pathways in cancer: IL6
hsa04066__11	1.65643104274744e-21	UP	9.52509017096915	9.94387836844232e-21	HIF-1 signaling pathway: SLC2A1
hsa03320__28	1.67141895073193e-21	DOWN	-9.52415450395825	1.00018987529468e-20	PPAR signaling pathway: ACSL1
hsa04530__5 15	1.93030317697273e-21	DOWN	-9.50918383178384	1.15144116493072e-20	Tight junction: IGSF5 MPDZ
hsa04068__66	1.9653335956039e-21	DOWN	-9.50731249776204	1.1686271601708e-20	FoxO signaling pathway: BNIP3
hsa04014__58 59	2.24889381368899e-21	DOWN	-9.49327749259853	1.33301939303521e-20	Ras signaling pathway: STK4 STK4
hsa04727__8	2.52713700634542e-21	DOWN	-9.48111382145682	1.49323598582486e-20	GABAergic synapse: ADCY1
hsa04611__34	2.83938994603522e-21	DOWN	-9.46895015031511	1.66725428393756e-20	Platelet activation: C02198*
hsa05032__13	2.83938994603522e-21	DOWN	-9.46895015031511	1.66725428393756e-20	Morphine addiction: PRKACA
hsa04114__59	2.86493271042352e-21	UP	9.46801448330421	1.67701201336006e-20	Oocyte meiosis: REC8*
hsa05211__23	2.89070274980292e-21	DOWN	-9.46707881629331	1.68684175990052e-20	Renal cell carcinoma: PDGFB
hsa05200__218	2.91670206366441e-21	DOWN	-9.46614314928241	1.69674401784069e-20	Pathways in cancer: CSF3R*
hsa04020__8	3.30592831229607e-21	DOWN	-9.4530438111298	1.91723435148282e-20	Calcium signaling pathway: PDE1A
hsa04924__49	3.39579350301634e-21	DOWN	-9.4502368100971	1.96329107451314e-20	Renin secretion: PDE1A
hsa04068__40	3.55096848132849e-21	DOWN	-9.44555847504259	2.04044947291016e-20	FoxO signaling pathway: CCND1
hsa05160__7	3.55096848132849e-21	UP	9.44555847504259	2.04044947291016e-20	Hepatitis C: IRF3
hsa05134__7	3.71315395679128e-21	DOWN	-9.44088013998809	2.12713911122281e-20	Legionellosis: IL18
hsa04068__46	3.84815977890578e-21	DOWN	-9.43713747194449	2.19777879166078e-20	FoxO signaling pathway: PLK4
hsa05214__52	3.91747206733457e-21	UP	9.43526613792269	2.23058485288535e-20	Glioma: E2F1*
hsa04973__5	4.16993131734034e-21	UP	9.42871646884638	2.36716040642976e-20	Carbohydrate digestion and absorption: SLC2A5
hsa05152__94	4.55873196416307e-21	DOWN	-9.41935979873737	2.58007751827181e-20	Tuberculosis: CAMP
hsa05130__28	4.76636754833762e-21	DOWN	-9.41468146368287	2.68949087787579e-20	Pathogenic Escherichia coli infection: ROCK1
hsa04630__30	5.84852517550248e-21	UP	9.39316112243215	3.29023317508058e-20	Jak-STAT signaling pathway: CDKN1A
hsa04068__51	5.90072367010826e-21	DOWN	-9.39222545542125	3.29983921908733e-20	FoxO signaling pathway: BCL6
hsa04068__56	5.90072367010826e-21	DOWN	-9.39222545542125	3.29983921908733e-20	FoxO signaling pathway: BCL6*
hsa04621__29	6.06009957978595e-21	DOWN	-9.38941845438855	3.3789101217857e-20	NOD-like receptor signaling pathway: CASP5
hsa03320__8	6.4487230009964e-21	DOWN	-9.38286878531225	3.58495577481427e-20	PPAR signaling pathway: GK
hsa05133__30	6.5062163132867e-21	DOWN	-9.38193311830135	3.60624792114033e-20	Pertussis: NOS2
hsa04010__120	6.62272803643524e-21	DOWN	-9.38006178427954	3.66003117072406e-20	MAPK signaling pathway: NFATC1
hsa04915__21	6.68175532101126e-21	DOWN	-9.37912611726864	3.68182353319066e-20	Estrogen signaling pathway: CREB3
hsa04921__58	7.63220692712408e-21	DOWN	-9.36509111210513	4.18102531080645e-20	Oxytocin signaling pathway: MEF2C
hsa05223__21	7.63220692712408e-21	DOWN	-9.36509111210513	4.18102531080645e-20	Non-small cell lung cancer: FOXO3*
hsa05211__43	7.70012482143841e-21	DOWN	-9.36415544509423	4.2059693428729e-20	Renal cell carcinoma: RAP1A
hsa04010__78	7.83775879754934e-21	DOWN	-9.36228411107243	4.26873877698412e-20	MAPK signaling pathway: MAP3K4
hsa05200__212	8.19257892436174e-21	DOWN	-9.35760577601793	4.44909127135136e-20	Pathways in cancer: CCND1***
hsa04340__33	8.56327655651604e-21	DOWN	-9.35292744096342	4.63700191633823e-20	Hedgehog signaling pathway: HHIP*
hsa04066__48	9.03006259696454e-21	DOWN	-9.34731343889802	4.87571483324608e-20	HIF-1 signaling pathway: PFKFB3
hsa04976__16	1.04936796303604e-20	DOWN	-9.33140709971271	5.64974900442615e-20	Bile secretion: CFTR
hsa04924__30	1.26288749029729e-20	UP	9.31175809248379	6.77990169791033e-20	Renin secretion: PDE3A
hsa05134__73	1.33142331124954e-20	DOWN	-9.30614409041839	7.12747692831305e-20	Legionellosis: CXCL1
hsa05150__14	1.37911189752012e-20	DOWN	-9.30240142237479	7.36179333931907e-20	Staphylococcus aureus infection: FPR1
hsa04360__11	1.49278735637758e-20	DOWN	-9.29398041927668	7.94602674966991e-20	Axon guidance: NFATC2
hsa04360__31	1.99447141513387e-20	DOWN	-9.26310340791696	1.05864739803292e-19	Axon guidance: CDC42*
hsa05205__304	2.31467187424907e-20	DOWN	-9.24719706873164	1.22514604273634e-19	Proteoglycans in cancer: MAPK1*****
hsa04810__48	2.46083909762393e-20	DOWN	-9.24064739965534	1.29885299562791e-19	Regulation of actin cytoskeleton: IQGAP2
hsa05215__39	2.66224580005519e-20	UP	9.23222639655723	1.40122124882457e-19	Prostate cancer: RB1
hsa04066__52	2.70916977240194e-20	DOWN	-9.23035506253543	1.41797493101483e-19	HIF-1 signaling pathway: FLT1
hsa04740__16	2.70916977240194e-20	DOWN	-9.23035506253543	1.41797493101483e-19	Olfactory transduction: PRKG1
hsa04668__120	2.75691126469938e-20	UP	9.22848372851363	1.43895451843615e-19	TNF signaling pathway: DNM1L
hsa04950__31	3.11520505236085e-20	UP	9.21538439036102	1.62145991506538e-19	Maturity onset diabetes of the young: NKX6-1*
hsa04014__61	3.14249136770185e-20	DOWN	-9.21444872335012	1.63114399997563e-19	Ras signaling pathway: RAP1A
hsa03460__16 49	3.25401951004027e-20	UP	9.21070605530652	1.68438089789688e-19	Fanconi anemia pathway: FANCM C19orf40
hsa04211__52	3.80629958260896e-20	DOWN	-9.1938640491103	1.9648453065171e-19	Longevity regulating pathway - mammal: PPARG
hsa04611__7	3.87311332471304e-20	DOWN	-9.1919927150885	1.99385751702351e-19	Platelet activation: ITPR1
hsa05162__13	3.97551356637152e-20	UP	9.1891857140558	2.04098087191587e-19	Measles: IRF7
hsa04152__38	4.04526257685412e-20	UP	9.187314380034	2.07113034929398e-19	AMPK signaling pathway: PFKL
hsa04068__60	4.15216030524231e-20	DOWN	-9.1845073790013	2.12008402542128e-19	FoxO signaling pathway: RAG1
hsa04664__47	4.37440260267057e-20	DOWN	-9.17889337693589	2.22750744997778e-19	Fc epsilon RI signaling pathway: MAPK8
hsa04933__59	4.93973445990572e-20	DOWN	-9.16579403878328	2.50858406761158e-19	AGE-RAGE signaling pathway in diabetic complications: SERPINE1
hsa04014__65	5.06996610428522e-20	DOWN	-9.16298703775058	2.56778067653691e-19	Ras signaling pathway: MLLT4*
hsa04066__47	5.24890116272702e-20	DOWN	-9.15924436970698	2.65125948515163e-19	HIF-1 signaling pathway: PGK1
hsa04726__10	5.34069539467396e-20	DOWN	-9.15737303568518	2.67085014716927e-19	Serotonergic synapse: PRKACA
hsa05020__24	5.38692356100636e-20	DOWN	-9.15643736867428	2.67085014716927e-19	Prion diseases: PRNP*
hsa05020__26	5.38692356100636e-20	DOWN	-9.15643736867428	2.67085014716927e-19	Prion diseases: PRNP**
hsa05020__25 8	5.38692356100636e-20	DOWN	-9.15643736867428	2.67085014716927e-19	Prion diseases: PRNP PRNP*
hsa05020__10 34	5.38692356100636e-20	DOWN	-9.15643736867428	2.67085014716927e-19	Prion diseases: PRNP PRNP***
hsa05218__21	5.3871857678401e-20	UP	9.15643736867428	2.67085014716927e-19	Melanoma: RB1
hsa05220__40	5.3871857678401e-20	UP	9.15643736867428	2.67085014716927e-19	Chronic myeloid leukemia: RB1
hsa04910__42	5.77379765817045e-20	DOWN	-9.14895203258707	2.85499099992165e-19	Insulin signaling pathway: PCK1
hsa04068__14	5.82401277872723e-20	DOWN	-9.14801636557617	2.87226247013871e-19	FoxO signaling pathway: G6PC
hsa04915__3 11	6.02922645790161e-20	DOWN	-9.14427369753257	2.95023867562425e-19	Estrogen signaling pathway: ESR1 C00951
hsa04915__12 14	6.02922645790161e-20	DOWN	-9.14427369753257	2.95023867562425e-19	Estrogen signaling pathway: ESR1 FOS
hsa04915__12 13	6.02922645790161e-20	DOWN	-9.14427369753257	2.95023867562425e-19	Estrogen signaling pathway: ESR1 C00951*
hsa05200__215	6.7467979321285e-20	DOWN	-9.13211002639086	3.29278787388817e-19	Pathways in cancer: CSF1R
hsa05212__34	6.86444312471067e-20	UP	9.13023869236906	3.34152555215838e-19	Pancreatic cancer: E2F1
hsa04530__5 10	7.54866711563498e-20	DOWN	-9.11994635524915	3.66510219903828e-19	Tight junction: IGSF5 MAGI1
hsa04750__59	8.08821309273371e-20	DOWN	-9.11246101916194	3.91694649516666e-19	Inflammatory mediator regulation of TRP channels: TRPV2
hsa05214__35	9.77642069234666e-20	UP	9.09187634492213	4.72233791283274e-19	Glioma: E2F1
hsa04622__11	9.9461535386664e-20	UP	9.09000501090033	4.79200576901389e-19	RIG-I-like receptor signaling pathway: IRF7
hsa05110__17	1.06547001705225e-19	DOWN	-9.08251967481312	5.12025105381377e-19	Vibrio cholerae infection: C00698*
hsa04972__42	1.07467043320959e-19	DOWN	-9.08158400780222	5.15129016326738e-19	Pancreatic secretion: CFTR
hsa04621__23	1.10274538258669e-19	DOWN	-9.07877700676952	5.27241367399592e-19	NOD-like receptor signaling pathway: CASP1
hsa04270__17	1.18120488587047e-19	DOWN	-9.07129167068231	5.61894678620408e-19	Vascular smooth muscle contraction: ITPR1
hsa05218__8	1.18120488587047e-19	UP	9.07129167068231	5.61894678620408e-19	Melanoma: CDK4
hsa05130__9	1.26517663798574e-19	DOWN	-9.06380633459511	6.00319924943234e-19	Pathogenic Escherichia coli infection: TLR4
hsa04971__49	1.27607944610684e-19	DOWN	-9.06287066758421	6.03968080411776e-19	Gastric acid secretion: KCNJ1
hsa05168__79	1.29816436994405e-19	UP	9.06099933356241	6.12877098272579e-19	Herpes simplex infection: EIF2S1
hsa04666__38	1.30934805391318e-19	DOWN	-9.0600636665515	6.16607767745077e-19	Fc gamma R-mediated phagocytosis: CFL1
hsa04520__58	1.563660621143e-19	UP	8.81585457670642	7.34529576781922e-19	Adherens junction: CDH1*
hsa04014__44	1.6082459609688e-19	DOWN	-9.03760765828989	7.53589566249471e-19	Ras signaling pathway: ETS1
hsa05152__20	1.99118581656889e-19	DOWN	-9.01421598301737	9.30706007296753e-19	Tuberculosis: FCGR1A
hsa04014__26	2.06046193123261e-19	DOWN	-9.01047331497377	9.60696766448159e-19	Ras signaling pathway: PRKCA
hsa05134__59	2.20594699452647e-19	UP	9.00298797888656	1.02598376304833e-18	Legionellosis: HSPA1A
hsa04213__54	2.99663995840421e-19	DOWN	-8.96930396649414	1.39029295847939e-18	Longevity regulating pathway - multiple species: SOD2*
hsa04010__54	3.10017826373172e-19	DOWN	-8.96556129845053	1.43478693535761e-18	MAPK signaling pathway: NR4A1
hsa03460__16 34	3.40348577895598e-19	UP	8.95526896133062	1.57128987190621e-18	Fanconi anemia pathway: FANCM STRA13
hsa05134__70	4.10073849433321e-19	DOWN	-8.93468428709081	1.88855088991473e-18	Legionellosis: IL6
hsa04723__73	4.4250757458978e-19	DOWN	-8.9262632839927	2.02797983574194e-18	Retrograde endocannabinoid signaling: MAPK14*
hsa04723__68	4.4250757458978e-19	DOWN	-8.9262632839927	2.02797983574194e-18	Retrograde endocannabinoid signaling: MAPK14
hsa05134__69	4.7345707360489e-19	DOWN	-8.9187779479055	2.16453975986275e-18	Legionellosis: IL1B*
hsa04068__68	5.23932536148036e-19	DOWN	-8.90754994377469	2.38948843549068e-18	FoxO signaling pathway: ATG12
hsa05200__185	5.37360332942058e-19	DOWN	-8.90474294274199	2.44479434769522e-18	Pathways in cancer: HHIP
hsa04530__20 62	5.60499395499161e-19	DOWN	-8.90006460768748	2.54390909213266e-18	Tight junction: ACTB SHROOM1
hsa04510__24 69	6.09770003606478e-19	DOWN	-8.89070793757848	2.76086225729294e-18	Focal adhesion: ZYX ACTB
hsa05223__28	6.41361026571951e-19	UP	8.88509393551307	2.89691675223244e-18	Non-small cell lung cancer: RB1
hsa05211__48	8.25243711018196e-19	DOWN	-8.85702392518605	3.71854420384458e-18	Renal cell carcinoma: JUN
hsa04115__2	8.899388863853e-19	UP	8.84860292208795	4.00046690793775e-18	p53 signaling pathway: IGFBP3
hsa04151__36	1.06102043785223e-18	DOWN	-8.82895391485903	4.7581322260724e-18	PI3K-Akt signaling pathway: PCK1
hsa04660__35	1.11560764350366e-18	DOWN	-8.82333991279363	4.99101610034137e-18	T cell receptor signaling pathway: NFATC1
hsa04151__26	1.12497133087313e-18	DOWN	-8.82240424578272	5.02095280453829e-18	PI3K-Akt signaling pathway: RBL2
hsa04660__44	1.18280569899017e-18	DOWN	-8.81679024371732	5.26656850332354e-18	T cell receptor signaling pathway: PAK4
hsa05164__34	1.20272882873192e-18	DOWN	-8.81491890969552	5.34261813046639e-18	Influenza A: IL1B
hsa05030__73	1.3745107043388e-18	DOWN	-8.79994823752111	6.09128682418069e-18	Cocaine addiction: NFKB1
hsa05010__12	1.39761938385627e-18	UP	8.79807690349931	6.17912193474338e-18	Alzheimer's disease: CASP3
hsa04360__131	1.51904388790637e-18	DOWN	-8.7887202333903	6.70019592811286e-18	Axon guidance: RAC1****
hsa04740__10	1.54455043881238e-18	DOWN	-8.7868488993685	6.79674537360295e-18	Olfactory transduction: ANO2
hsa05223__7	1.58360526986902e-18	DOWN	-8.7840418983358	6.95232313571004e-18	Non-small cell lung cancer: FOXO3
hsa05161__45	1.67856601221956e-18	UP	8.77749222925949	7.35204087869595e-18	Hepatitis B: PCNA
hsa04961__12	1.87007704125127e-18	DOWN	-8.76532855811778	8.17180176863054e-18	Endocrine and other factor-regulated calcium reabsorption: SLC8A1
hsa04724__65	2.06580515626939e-18	DOWN	-8.75410055398697	9.00614359310946e-18	Glutamatergic synapse: GRM3
hsa04010__67	2.26317534006579e-18	UP	8.74380821686707	9.84376496292504e-18	MAPK signaling pathway: ELK1
hsa04530__7 52	2.35887361259582e-18	DOWN	-8.73912988181256	1.02363129747518e-17	Tight junction: PARD6A MPP5
hsa04270__65	2.52030548207931e-18	DOWN	-8.73164454572536	1.09116451631959e-17	Vascular smooth muscle contraction: NPR2
hsa04152__15	2.85312957895138e-18	DOWN	-8.71760954056185	1.22959414652515e-17	AMPK signaling pathway: FOXO1
hsa04390__60	2.85312957895138e-18	DOWN	-8.71760954056185	1.22959414652515e-17	Hippo signaling pathway: CTGF*
hsa05213__11	2.97341402318275e-18	DOWN	-8.71293120550734	1.27558103871242e-17	Endometrial cancer: FOXO3
hsa05217__5	2.97341402318275e-18	DOWN	-8.71293120550734	1.27558103871242e-17	Basal cell carcinoma: BMP2
hsa04930__15	3.12437863026816e-18	DOWN	-8.70731720344194	1.33729099003961e-17	Type II diabetes mellitus: C00031*
hsa04911__25	3.22920039184526e-18	DOWN	-8.70357453539834	1.37901534915392e-17	Insulin secretion: PRKCA
hsa04213__71	3.53569824185827e-18	DOWN	-8.69328219827843	1.50648004454687e-17	Longevity regulating pathway - multiple species: SIRT1**
hsa04664__25	3.65413003119929e-18	DOWN	-8.68953953023482	1.5534186263854e-17	Fc epsilon RI signaling pathway: MAPK14
hsa04931__124	3.77647656392125e-18	DOWN	-8.68579686219122	1.60180574799278e-17	Insulin resistance: FOXO1*
hsa04726__64	3.87088213869014e-18	UP	8.68298986115852	1.63815034653125e-17	Serotonergic synapse: CASP3
hsa04360__33 134	4.10031760135027e-18	DOWN	-8.67644019208222	1.73134758942408e-17	Axon guidance: NCK1 PAK4
hsa05166__89 90	4.48825887506491e-18	DOWN	-8.66614785496231	1.89090547673699e-17	HTLV-I infection: CHUK IKBKG
hsa04022__23	4.6002072120538e-18	UP	8.66334085392961	1.93373363567094e-17	cGMP-PKG signaling pathway: CACNA1C
hsa04151__5	5.28864037969558e-18	UP	8.64743451474429	2.21321943729354e-17	PI3K-Akt signaling pathway: EIF4B
hsa05162__23	5.28864037969558e-18	UP	8.64743451474429	2.21321943729354e-17	Measles: IRF3
hsa04921__57	5.37603873727459e-18	DOWN	-8.64556318072249	2.24479484163088e-17	Oxytocin signaling pathway: FOS
hsa04919__103	5.64687840262807e-18	DOWN	-8.63994917865709	2.35265732118362e-17	Thyroid hormone signaling pathway: CCND1
hsa04972__18	6.54282750821768e-18	DOWN	-8.62310717246087	2.71990550618164e-17	Pancreatic secretion: PRKCA
hsa04722__35	6.70522181468409e-18	DOWN	-8.62030017142817	2.78126088074865e-17	Neurotrophin signaling pathway: FOXO3
hsa05200__213	6.9279508378222e-18	DOWN	-8.61655750338457	2.86731709785637e-17	Pathways in cancer: CSF2RA
hsa04972__21	7.45613976728904e-18	DOWN	-8.60813650028646	3.07913991708486e-17	Pancreatic secretion: KCNQ1
hsa04211__29	7.76655204236618e-18	DOWN	-8.60345816523196	3.19329349838207e-17	Longevity regulating pathway - mammal: EIF4E
hsa04664__46	7.76655204236618e-18	DOWN	-8.60345816523196	3.19329349838207e-17	Fc epsilon RI signaling pathway: PLA2G4B
hsa04668__141	8.15591942263209e-18	DOWN	-8.59784416316656	3.34606388539862e-17	TNF signaling pathway: JUN*
hsa04390__75	8.9933546096467e-18	DOWN	-8.58661615903575	3.68159331405799e-17	Hippo signaling pathway: NKD1
hsa04360__20	9.14094846650013e-18	UP	8.58474482501395	3.72577921226762e-17	Axon guidance: ROCK1
hsa05161__195	9.14094846650013e-18	DOWN	-8.58474482501395	3.72577921226762e-17	Hepatitis B: IL6
hsa04066__59	9.29093242363825e-18	DOWN	-8.58287349099215	3.77871472381305e-17	HIF-1 signaling pathway: NOS2
hsa04623__25	9.91554174367969e-18	DOWN	-8.57538815490494	4.0153670121496e-17	Cytosolic DNA-sensing pathway: NFKB1*
hsa04916__7	9.91554174367969e-18	DOWN	-8.57538815490494	4.0153670121496e-17	Melanogenesis: TYRP1
hsa05221__5	1.15699337973725e-17	DOWN	-8.55761048169783	4.67524851726085e-17	Acute myeloid leukemia: SPI1
hsa04010__119	1.17591827697086e-17	DOWN	-8.55573914767603	4.74152455456706e-17	MAPK signaling pathway: NFATC3
hsa05150__13	1.3065958428736e-17	DOWN	-8.54357547653432	5.25715971897109e-17	Staphylococcus aureus infection: C5AR1
hsa04931__87	1.34961463805994e-17	DOWN	-8.53983280849071	5.41864509597142e-17	Insulin resistance: C00031*
hsa04010__79	1.47525538213321e-17	UP	8.5295404713708	5.91045813012431e-17	MAPK signaling pathway: HSPB1
hsa04012__22	1.51147949439163e-17	UP	8.5267334703381	6.04270206374868e-17	ErbB signaling pathway: EIF4EBP1
hsa04919__44	1.7200146560517e-17	DOWN	-8.51176279816369	6.8617994452678e-17	Thyroid hormone signaling pathway: PFKFB2
hsa04910__43	1.73395201574694e-17	DOWN	-8.51082713115279	6.90274541861971e-17	Insulin signaling pathway: G6PC
hsa04724__44	1.74800079975163e-17	DOWN	-8.50989146414189	6.94396089372794e-17	Glutamatergic synapse: PRKACA*
hsa05152__98	1.77643616111641e-17	UP	8.50802013012009	7.04203279902477e-17	Tuberculosis: IL23A
hsa04620__39	1.84953682058127e-17	DOWN	-8.50334179506559	7.31637828604674e-17	Toll-like receptor signaling pathway: IL6
hsa04010__65	1.92560397865e-17	UP	8.49866346001108	7.60128125185579e-17	MAPK signaling pathway: ELK4
hsa04010__107	1.94118375025062e-17	DOWN	-8.49772779300018	7.64671754029543e-17	MAPK signaling pathway: MAP3K2
hsa04010__88 92	2.22588977439541e-17	DOWN	-8.48182145381487	8.74988888303135e-17	MAPK signaling pathway: ECSIT TRAF6
hsa04066__43	2.28024377157892e-17	DOWN	-8.47901445278217	8.9448393461311e-17	HIF-1 signaling pathway: PFKL
hsa04915__30	2.43167256075702e-17	DOWN	-8.47152911669496	9.51898487846341e-17	Estrogen signaling pathway: CREB3*
hsa04068__72	2.61391027470641e-17	DOWN	-8.46310811359685	1.0189911631065e-16	FoxO signaling pathway: SMAD2
hsa04919__26	2.61391027470641e-17	DOWN	-8.46310811359685	1.0189911631065e-16	Thyroid hormone signaling pathway: THRB
hsa05166__53 146	2.85502258387613e-17	DOWN	-8.45281577647695	1.11068062838577e-16	HTLV-I infection: CREB1 CRTC2
hsa04919__40	2.87800026782387e-17	DOWN	-8.45188010946605	1.11730630232253e-16	Thyroid hormone signaling pathway: RCAN2
hsa04010__13	2.97174954799599e-17	UP	8.44813744142244	1.15132317539886e-16	MAPK signaling pathway: STMN1
hsa05205__188	3.1938413958993e-17	DOWN	-8.43971643832434	1.2348205726121e-16	Proteoglycans in cancer: TNF
hsa04931__104	3.37782900984218e-17	UP	8.43316676924803	1.30327324630256e-16	Insulin resistance: C00369*
hsa04270__24	3.45984576396995e-17	DOWN	-8.43035976821533	1.32945811666657e-16	Vascular smooth muscle contraction: ACTA2
hsa05133__24	3.45984576396995e-17	DOWN	-8.43035976821533	1.32945811666657e-16	Pertussis: NFKB1
hsa05032__4	3.48761883328105e-17	DOWN	-8.42942410120443	1.33739505872145e-16	Morphine addiction: ADCY1
hsa04970__12	3.54301073936427e-17	UP	8.42755276718263	1.35586907928014e-16	Salivary secretion: BEST2
hsa04910__48	3.6298172643021e-17	DOWN	-8.42474576614993	1.38626557715928e-16	Insulin signaling pathway: PPARGC1A
hsa05010__61	3.83854863676487e-17	UP	8.41819609707362	1.46300869948908e-16	Alzheimer's disease: GAPDH
hsa05200__121 122	3.93158901390007e-17	DOWN	-8.41538909604092	1.49241530446833e-16	Pathways in cancer: SMAD2 SMAD4
hsa05212__38 39	3.93158901390007e-17	DOWN	-8.41538909604092	1.49241530446833e-16	Pancreatic cancer: SMAD2 SMAD4
hsa04950__1	3.96309409685572e-17	UP	8.41445342903002	1.50134149354675e-16	Maturity onset diabetes of the young: HNF1B
hsa04650__25	4.19071161153736e-17	DOWN	-8.40790375995371	1.58437567768183e-16	Natural killer cell mediated cytotoxicity: SH2D1B
hsa04660__40 41	4.3960412816387e-17	DOWN	-8.40228975788831	1.65866698156609e-16	T cell receptor signaling pathway: LAT GRAP2
hsa04660__41 46	4.50239599759725e-17	DOWN	-8.39948275685561	1.69539119829363e-16	T cell receptor signaling pathway: GRAP2 LCP2
hsa04010__66	4.91452857741933e-17	UP	8.3891904197357	1.84687983939418e-16	MAPK signaling pathway: TP53
hsa05133__27	5.19594250827453e-17	DOWN	-8.38264075065939	1.94873771917122e-16	Pertussis: IRF3
hsa04115__52 53	5.40662533410938e-17	UP	8.37796241560489	2.02371494079512e-16	p53 signaling pathway: CDK4 CCND1
hsa04920__3	6.04240455227846e-17	DOWN	-8.36486307745228	2.2571924758909e-16	Adipocytokine signaling pathway: C15493
hsa05219__12	6.9691619873387e-17	UP	8.34802107125607	2.5982252726606e-16	Bladder cancer: ERBB2
hsa04722__46	7.84747611813484e-17	DOWN	-8.33398606609256	2.91988269821294e-16	Neurotrophin signaling pathway: ATF4*
hsa04062__38	8.29387569468551e-17	DOWN	-8.32743639701625	3.07987992693954e-16	Chemokine signaling pathway: NCF1
hsa04115__58	9.56000595774399e-17	UP	8.31059439082004	3.5430475728996e-16	p53 signaling pathway: CASP3
hsa04270__46	1.01822007572392e-16	UP	8.30310905473284	3.7662116580418e-16	Vascular smooth muscle contraction: ITPR1*
hsa04068__55	1.0343887235557e-16	DOWN	-8.30123772071103	3.81849982624982e-16	FoxO signaling pathway: ATM
hsa04022__63	1.04256772358407e-16	DOWN	-8.30030205370013	3.84114657375384e-16	cGMP-PKG signaling pathway: C00575
hsa05205__81	1.09299805110288e-16	UP	8.29468805163473	4.01906719769533e-16	Proteoglycans in cancer: CTTN
hsa04670__28 41 49	1.15487935275338e-16	DOWN	-8.28813838255842	4.23831699965546e-16	Leukocyte transendothelial migration: ACTB CTNNA1 CTNNB1
hsa05321__152	1.23953939099039e-16	UP	8.27971737946032	4.54014525471919e-16	Inflammatory bowel disease (IBD): FOXP3*
hsa04152__89	1.29934934012775e-16	DOWN	-8.27410337739491	4.74995605077828e-16	AMPK signaling pathway: CFTR
hsa04350__10	1.38354213029385e-16	UP	8.26661804130771	5.04791390839252e-16	TGF-beta signaling pathway: SMAD4
hsa04151__2	1.42763312233158e-16	DOWN	-8.26287537326411	5.19868728073846e-16	PI3K-Akt signaling pathway: EIF4E
hsa04520__7 68	1.46160778423547e-16	UP	8.2600683722314	5.31211030285968e-16	Adherens junction: CDH1 CTNNB1
hsa04921__56	1.59314076424355e-16	DOWN	-8.24977603511149	5.77897972203402e-16	Oxytocin signaling pathway: JUN
hsa05231__50	1.68284977914043e-16	DOWN	-8.24322636603519	6.09262954721556e-16	Choline metabolism in cancer: WASF2
hsa04071__69	1.83397913598674e-16	DOWN	-8.23293402891528	6.62701307022902e-16	Sphingolipid signaling pathway: RAC1
hsa04068__96	1.96751903353196e-16	DOWN	-8.22451302581718	7.0959083762122e-16	FoxO signaling pathway: CCNG2
hsa04210__59	2.11063490498422e-16	UP	8.21609202271907	7.59747698556581e-16	Apoptosis: PMAIP1
hsa03320__10	2.35390059342406e-16	DOWN	-8.20299268456646	8.45693922570518e-16	PPAR signaling pathway: PLIN1
hsa04062__8 41	2.54438252521125e-16	DOWN	-8.19363601445745	9.12384497112967e-16	Chemokine signaling pathway: PXN PTK2B
hsa05200__211	2.70763944770757e-16	DOWN	-8.18615067837025	9.69077051855718e-16	Pathways in cancer: CXCL8
hsa04211__50	2.88121231101347e-16	DOWN	-8.17866534228304	1.02923915064531e-15	Longevity regulating pathway - mammal: PPARGC1A*
hsa04151__102	3.23672932188213e-16	DOWN	-8.16463033711953	1.15404447738454e-15	PI3K-Akt signaling pathway: C8orf44-SGK3
hsa04662__16	3.26191112343737e-16	UP	8.16369467010863	1.15643981149789e-15	B cell receptor signaling pathway: VAV3
hsa04810__8 79	3.26191112343737e-16	DOWN	-8.16369467010863	1.15643981149789e-15	Regulation of actin cytoskeleton: ARPC5 ACTB
hsa04810__8 82	3.26191112343737e-16	DOWN	-8.16369467010863	1.15643981149789e-15	Regulation of actin cytoskeleton: ARPC5 ACTB*
hsa04911__31	3.49741303791993e-16	DOWN	-8.15527366701052	1.23759681699652e-15	Insulin secretion: CAMK2A
hsa04722__38	4.30912510098269e-16	DOWN	-8.13001065771621	1.52196354600498e-15	Neurotrophin signaling pathway: ATF4
hsa04066__88	4.54824980387424e-16	DOWN	-8.1234609886399	1.60040475308609e-15	HIF-1 signaling pathway: BCL2
hsa04211__62	4.54824980387424e-16	UP	8.1234609886399	1.60040475308609e-15	Longevity regulating pathway - mammal: EHMT2
hsa04620__34	4.69071489077757e-16	DOWN	-8.1197183205963	1.64744921117216e-15	Toll-like receptor signaling pathway: IL1B
hsa04915__28	4.72701283082843e-16	DOWN	-8.1187826535854	1.65710020692661e-15	Estrogen signaling pathway: KCNJ3
hsa05133__73	4.80044110025925e-16	DOWN	-8.1169113195636	1.67970741664565e-15	Pertussis: FOS
hsa05221__35	4.9506859229436e-16	UP	8.11316865151999	1.72905926565261e-15	Acute myeloid leukemia: EIF4EBP1
hsa05205__129	5.10556260884782e-16	DOWN	-8.10942598347639	1.7765466929676e-15	Proteoglycans in cancer: AKT3*
hsa05211__46	5.10556260884782e-16	DOWN	-8.10942598347639	1.7765466929676e-15	Renal cell carcinoma: AKT3
hsa04024__115	5.18478166252964e-16	DOWN	-8.10755464945459	1.8007772169858e-15	cAMP signaling pathway: F2R
hsa04950__16	5.26521171631402e-16	UP	8.10568331543279	1.8219765773396e-15	Maturity onset diabetes of the young: PAX4
hsa05205__120	5.26521171631402e-16	UP	8.10568331543279	1.8219765773396e-15	Proteoglycans in cancer: PLAU
hsa04750__7	5.38805700168812e-16	UP	8.10287631440008	1.85764387269211e-15	Inflammatory mediator regulation of TRP channels: TRPV1
hsa04750__58	5.38805700168812e-16	UP	8.10287631440008	1.85764387269211e-15	Inflammatory mediator regulation of TRP channels: TRPV1**
hsa04920__28	5.73005183211915e-16	UP	8.09539097831288	1.9719354198813e-15	Adipocytokine signaling pathway: SLC2A1
hsa05014__2	5.77426282527584e-16	DOWN	-8.09445531130198	1.98351733979768e-15	Amyotrophic lateral sclerosis (ALS): SLC1A2
hsa04071__24	5.90892244484132e-16	DOWN	-8.09164831026928	2.02607030544833e-15	Sphingolipid signaling pathway: PTEN
hsa04062__22 41	5.95449297892786e-16	DOWN	-8.09071264325838	2.03797674087531e-15	Chemokine signaling pathway: CRK PTK2B
hsa05152__13	6.00040978061752e-16	DOWN	-8.08977697624747	2.04995817777824e-15	Tuberculosis: LAMP1
hsa04662__32 51	6.88917183448446e-16	UP	8.07293497005126	2.34932012286684e-15	B cell receptor signaling pathway: BLNK GRB2
hsa05220__4	7.43772560399768e-16	DOWN	-8.06357829994226	2.53179101628834e-15	Chronic myeloid leukemia: PTPN11
hsa05222__44	7.61052791094861e-16	UP	8.06077129890955	2.58592801892811e-15	Small cell lung cancer: RB1
hsa05205__352	7.72698125279834e-16	DOWN	-8.05889996488775	2.62075772094009e-15	Proteoglycans in cancer: ITGA5*
hsa04962__10	8.15301862525638e-16	DOWN	-8.05235029581145	2.76027423366788e-15	Vasopressin-regulated water reabsorption: AQP2
hsa04972__39	1.27820823326576e-15	DOWN	-7.99714594216831	4.31970012645029e-15	Pancreatic secretion: KCNMA1*
hsa04261__37	1.33778965724915e-15	DOWN	-7.9915319401029	4.51293853854785e-15	Adrenergic signaling in cardiomyocytes: CREB3
hsa04152__35	1.35825165767581e-15	DOWN	-7.9896606060811	4.57375423794418e-15	AMPK signaling pathway: PFKFB1
hsa04972__23	1.4652772522573e-15	DOWN	-7.98030393597209	4.92532371554824e-15	Pancreatic secretion: KCNMA1
hsa04310__32	1.58059970675966e-15	UP	7.97094726586309	5.30347651607392e-15	Wnt signaling pathway: PPARD
hsa04914__15	1.73083209738168e-15	UP	7.95971926173228	5.79720768445663e-15	Progesterone-mediated oocyte maturation: ANAPC10
hsa04933__28	1.9532075558278e-15	DOWN	-7.94474858955787	6.5303861163709e-15	AGE-RAGE signaling pathway in diabetic complications: VCAM1
hsa04350__50	2.04366031287026e-15	DOWN	-7.93913458749246	6.82067091986361e-15	TGF-beta signaling pathway: AMHR2
hsa05152__9	2.2540304970047e-15	DOWN	-7.92697091635075	7.50943848204225e-15	Tuberculosis: TCIRG1
hsa04919__32	2.28823427779754e-15	DOWN	-7.92509958232895	7.60989771324172e-15	Thyroid hormone signaling pathway: PLN
hsa04919__25	2.43023514717409e-15	UP	7.91761424624175	8.06786544441715e-15	Thyroid hormone signaling pathway: MTOR
hsa04540__18 19	2.48569331613009e-15	DOWN	-7.91480724520904	8.23742105997962e-15	Gap junction: GJA1 GJA1***
hsa04010__64	2.67970723356e-15	UP	7.90545057510004	8.8647357251043e-15	MAPK signaling pathway: DDIT3
hsa04919__104	2.72026249364323e-15	DOWN	-7.90357924107824	8.98308123999231e-15	Thyroid hormone signaling pathway: MYC
hsa04380__38	3.61636228470906e-15	DOWN	-7.86802389466401	1.19213065490672e-14	Osteoclast differentiation: FOS
hsa04064__96	3.67083975735569e-15	DOWN	-7.86615256064221	1.20796986060794e-14	NF-kappa B signaling pathway: BCL2A1
hsa03320__64	3.69838068694992e-15	DOWN	-7.86521689363131	1.21490512426204e-14	PPAR signaling pathway: APOA5
hsa04115__64	3.75407427005864e-15	UP	7.86334555960951	1.23104808960562e-14	p53 signaling pathway: PMAIP1
hsa04066__29	4.2620444198205e-15	DOWN	-7.84743922042419	1.39276199388569e-14	HIF-1 signaling pathway: LDHA
hsa04620__87	4.2620444198205e-15	DOWN	-7.84743922042419	1.39276199388569e-14	Toll-like receptor signaling pathway: CCL4L1
hsa04722__53	4.35845865485556e-15	DOWN	-7.84463221939149	1.42179580077667e-14	Neurotrophin signaling pathway: JUN
hsa05211__21	4.42392440197928e-15	DOWN	-7.84276088536969	1.44065059814888e-14	Renal cell carcinoma: TGFB1*
hsa04612__17 28	4.55777345800121e-15	DOWN	-7.83901821732609	1.48167064491077e-14	Antigen processing and presentation: CD4 HLA-DMA
hsa04520__44 47	4.69560741839824e-15	DOWN	-7.83527554928248	1.52384220020212e-14	Adherens junction: ACTB TJP1
hsa04919__42	5.09616233397549e-15	UP	7.82498321216258	1.65098086647241e-14	Thyroid hormone signaling pathway: SLC2A1
hsa04210__57	5.32863367248627e-15	UP	7.81936921009717	1.72332231852009e-14	Apoptosis: BAK1
hsa04014__42	5.36838089951559e-15	DOWN	-7.81843354308627	1.73319376463742e-14	Ras signaling pathway: PLA2G4B
hsa05205__109	5.61306670479957e-15	DOWN	-7.81281954102087	1.80908273384535e-14	Proteoglycans in cancer: SMAD2
hsa04151__25	5.65490143154412e-15	DOWN	-7.81188387400997	1.81944516949853e-14	PI3K-Akt signaling pathway: CDKN1B
hsa04062__59	5.82533141035968e-15	DOWN	-7.80814120596636	1.8678835699771e-14	Chemokine signaling pathway: FOXO3
hsa05166__120	5.82533141035968e-15	UP	7.80814120596636	1.8678835699771e-14	HTLV-I infection: E2F1
hsa05200__201	6.00081508673146e-15	DOWN	-7.80439853792276	1.92087419897247e-14	Pathways in cancer: PDGFB
hsa04911__4	6.55908275726271e-15	DOWN	-7.79317053379195	2.09600620763548e-14	Insulin secretion: CACNA1C
hsa05161__100	6.65697120693048e-15	UP	7.79129919977015	2.12367553443504e-14	Hepatitis B: MMP9*
hsa04971__55	6.85708164667672e-15	DOWN	-7.78755653172655	2.1838061718823e-14	Gastric acid secretion: MYLK4
hsa04151__37	7.01103879113487e-15	DOWN	-7.78474953069385	2.22529423792946e-14	PI3K-Akt signaling pathway: G6PC
hsa04950__7	7.01103879113487e-15	UP	7.78474953069385	2.22529423792946e-14	Maturity onset diabetes of the young: FOXA3
hsa04211__23	7.89141795729849e-15	DOWN	-7.76977885851943	2.50050157533961e-14	Longevity regulating pathway - mammal: SOD2
hsa04152__62	8.94609439010318e-15	UP	7.75387251933412	2.82991773720604e-14	AMPK signaling pathway: EIF4EBP1
hsa04062__53	9.07894925341527e-15	DOWN	-7.75200118531232	2.8671169154903e-14	Chemokine signaling pathway: NFKB1
hsa03320__59	9.48927296666487e-15	DOWN	-7.74638718324692	2.99166844032941e-14	PPAR signaling pathway: NR1H3
hsa05152__88 89	9.84510687873905e-15	DOWN	-7.74170884819241	3.09865256702692e-14	Tuberculosis: ITGAX ITGB2
hsa03320__7	1.05966196046336e-14	DOWN	-7.73235217808341	3.32404811971729e-14	PPAR signaling pathway: AQP7
hsa04066__64	1.05966196046336e-14	DOWN	-7.73235217808341	3.32404811971729e-14	HIF-1 signaling pathway: LTBR
hsa04062__35 36 37	1.08328845814783e-14	DOWN	-7.7295451770507	3.3924983547663e-14	Chemokine signaling pathway: PARD3 PRKCZ TIAM1
hsa04360__29	1.09932665513289e-14	UP	7.7276738430289	3.43699631446706e-14	Axon guidance: RASA1
hsa05166__74	1.49560293828973e-14	DOWN	-7.68837582857107	4.6681693040638e-14	HTLV-I infection: NFKB1
hsa05220__19 41	1.68101642515563e-14	DOWN	-7.67340515639666	5.23819214405876e-14	Chronic myeloid leukemia: SMAD4 SMAD3
hsa05020__52	1.82142324842119e-14	DOWN	-7.66311281927675	5.66631503937651e-14	Prion diseases: FYN
hsa04024__113	2.00228433375355e-14	DOWN	-7.65094914813505	6.21866489772385e-14	cAMP signaling pathway: PTCH1
hsa04920__5	2.10687284795377e-14	DOWN	-7.64439947905874	6.53269650380385e-14	Adipocytokine signaling pathway: NFKBIA
hsa05140__26	2.24927125555562e-14	DOWN	-7.63597847596063	6.96273589652225e-14	Leishmaniasis: C00533
hsa04530__11 20 16	2.28217848380997e-14	DOWN	-7.63410714193883	7.05298251822194e-14	Tight junction: TJP1 ACTB CTTN
hsa03320__33	2.36653259222066e-14	DOWN	-7.62942880688433	7.30166624102236e-14	PPAR signaling pathway: CYP7A1
hsa04740__39	2.40112640391762e-14	DOWN	-7.62755747286253	7.39625657862494e-14	Olfactory transduction: PRKG1*
hsa05216__12	2.62851123008246e-14	UP	7.57516012025209	8.08342487941889e-14	Thyroid cancer: CDH1
hsa04211__57	2.755588897764e-14	DOWN	-7.60977979965541	8.44657673556045e-14	Longevity regulating pathway - mammal: ATG5
hsa05134__9	2.755588897764e-14	DOWN	-7.60977979965541	8.44657673556045e-14	Legionellosis: CASP7
hsa05205__34	2.87786474915901e-14	DOWN	-7.60416579759001	8.80701606460875e-14	Proteoglycans in cancer: SLC9A1
hsa05140__16	2.94098834889608e-14	UP	7.60135879655731	8.98555627248086e-14	Leishmaniasis: STAT1
hsa05205__77	3.07128907104109e-14	DOWN	-7.5957447944919	9.36842883845165e-14	Proteoglycans in cancer: MIR21
hsa04910__14	3.32526497153408e-14	UP	7.585452457372	1.0126698349291e-13	Insulin signaling pathway: C00369
hsa04152__54	3.52278952818492e-14	DOWN	-7.57796712128479	1.07108762515525e-13	AMPK signaling pathway: SLC2A4*
hsa04010__58	5.11912617655765e-14	UP	7.52931243671795	1.55393183937832e-13	MAPK signaling pathway: CDC25B
hsa05152__51	5.34390476532916e-14	UP	7.52369843465255	1.61954791194411e-13	Tuberculosis: CASP3
hsa05164__35	5.53861041534863e-14	DOWN	-7.51902009959805	1.67585329636716e-13	Influenza A: IL18
hsa04024__76	5.90681057582519e-14	DOWN	-7.51059909649994	1.78438859678063e-13	cAMP signaling pathway: C00416
hsa05132__13	5.94917817647352e-14	DOWN	-7.50966342948904	1.79430269560092e-13	Salmonella infection: FOS
hsa05152__24 25	6.07803165058736e-14	DOWN	-7.50685642845634	1.83022779991244e-13	Tuberculosis: ITGB2 ITGAM
hsa04621__34 35	6.25423258465499e-14	DOWN	-7.50311376041273	1.88027248425068e-13	NOD-like receptor signaling pathway: CASP1 PYCARD
hsa04725__25	6.43539993533678e-14	UP	7.49937109236913	1.93164799976003e-13	Cholinergic synapse: CACNA1A
hsa04213__52	6.66912745437153e-14	DOWN	-7.49469275731463	1.99861092292888e-13	Longevity regulating pathway - multiple species: SOD2
hsa04610__57	6.76493750675164e-14	UP	7.49282142329283	2.02409515528445e-13	Complement and coagulation cascades: PLAUR
hsa05200__227	7.06055964841991e-14	DOWN	-7.48720742122742	2.10918785045803e-13	Pathways in cancer: FOXO1
hsa04919__88	7.36887173915144e-14	DOWN	-7.48159341916202	2.19779523775644e-13	Thyroid hormone signaling pathway: FOXO1
hsa04972__51	7.80062160706739e-14	DOWN	-7.47410808307481	2.32287923925192e-13	Pancreatic secretion: CLCA1
hsa04918__14	7.96885859027725e-14	DOWN	-7.47130108204211	2.36922235619161e-13	Thyroid hormone synthesis: DUOX2
hsa04540__10	8.25721298876609e-14	DOWN	-7.46662274698761	2.451074756065e-13	Gap junction: C00533
hsa05215__12	9.93017868025609e-14	DOWN	-7.44229540470419	2.9430292965617e-13	Prostate cancer: KLK3
hsa04115__31	1.02881303385051e-13	DOWN	-7.43761706964969	3.04431447339388e-13	p53 signaling pathway: ADGRB1
hsa05100__55	1.08106523726031e-13	DOWN	-7.43106740057338	3.19390185662284e-13	Bacterial invasion of epithelial cells: ACTB*
hsa05012__57	1.09646760871235e-13	UP	7.42919606655158	3.23432125081712e-13	Parkinson's disease: CASP3
hsa04062__40	1.11997636507228e-13	DOWN	-7.42638906551888	3.2933264318792e-13	Chemokine signaling pathway: PRKACA
hsa04932__58	1.11997636507228e-13	UP	7.42638906551888	3.2933264318792e-13	Non-alcoholic fatty liver disease (NAFLD): BAX
hsa04664__30	1.16026305565732e-13	DOWN	-7.42171073046437	3.4064598149689e-13	Fc epsilon RI signaling pathway: PRKCA
hsa04360__4	1.26285234349003e-13	DOWN	-7.41048272633356	3.70187137818684e-13	Axon guidance: GNAI1*
hsa04210__50	1.31743875962979e-13	DOWN	-7.40486872426816	3.84987158529451e-13	Apoptosis: SPTA1
hsa05200__203	1.31743875962979e-13	UP	7.40486872426816	3.84987158529451e-13	Pathways in cancer: TGFA*
hsa05215__25	1.37434205621185e-13	DOWN	-7.39925472220276	4.00992037829515e-13	Prostate cancer: FOXO1
hsa05200__188	1.39384124577674e-13	DOWN	-7.39738338818096	4.06050806327829e-13	Pathways in cancer: KLK3
hsa05034__61	1.46425324938277e-13	DOWN	-7.39083371910465	4.25902764023254e-13	Alcoholism: CRH
hsa05168__122	1.50604583733484e-13	UP	7.38709105106105	4.37381781816408e-13	Herpes simplex infection: CASP3
hsa04115__54	1.51667578753832e-13	UP	7.38615538405015	4.39789167405016e-13	p53 signaling pathway: PERP
hsa05160__15 16	1.66175906033352e-13	DOWN	-7.37399171290844	4.81116375095022e-13	Hepatitis C: TRAF6 RIPK1
hsa04022__60	1.68525777498182e-13	DOWN	-7.37212037888664	4.86420792502432e-13	cGMP-PKG signaling pathway: TRPC6*
hsa04071__66	1.68525777498182e-13	DOWN	-7.37212037888664	4.86420792502432e-13	Sphingolipid signaling pathway: C01245
hsa05016__60	1.70908289635801e-13	UP	7.37024904486483	4.917866404681e-13	Huntington's disease: CASP3*
hsa05134__35	1.70908289635801e-13	UP	7.37024904486483	4.917866404681e-13	Legionellosis: CASP3
hsa04971__37	1.75773021607129e-13	DOWN	-7.36650637682123	5.05011479510392e-13	Gastric acid secretion: KCNQ1
hsa04960__27	1.87221534397802e-13	DOWN	-7.35808537372313	5.3708284447858e-13	Aldosterone-regulated sodium reabsorption: KCNJ1
hsa05016__22 9	2.65488978819412e-13	UP	7.31130202317809	7.60447852441578e-13	Huntington's disease: DLG4 HTT
hsa05216__5	2.74893307738167e-13	UP	7.30662368812359	7.86186491993935e-13	Thyroid cancer: MAPK1
hsa04610__23	2.88611217073152e-13	UP	7.30007401904728	8.2416485848093e-13	Complement and coagulation cascades: BDKRB1
hsa04210__84	3.11537554922194e-13	DOWN	-7.28978168192737	8.88283862972386e-13	Apoptosis: FAS**
hsa04622__45	3.24787203091219e-13	UP	7.28416767986197	9.24659325164242e-13	RIG-I-like receptor signaling pathway: MAPK14
hsa05152__15	3.52968174778509e-13	DOWN	-7.27293967573116	1.00336944086054e-12	Tuberculosis: CTSD
hsa05034__84	3.60380513764443e-13	DOWN	-7.27013267469846	1.02289272713503e-12	Alcoholism: FOSB
hsa04213__61	3.73075512050038e-13	DOWN	-7.26545433964396	1.05414870246921e-12	Longevity regulating pathway - multiple species: ATG5
hsa04722__73 77	3.73075512050038e-13	DOWN	-7.26545433964396	1.05414870246921e-12	Neurotrophin signaling pathway: NGFRAP1 YWHAE
hsa05030__78	3.73075512050038e-13	DOWN	-7.26545433964396	1.05414870246921e-12	Cocaine addiction: GRIA2
hsa05200__219	4.02570394039977e-13	DOWN	-7.25516200252405	1.13578043603771e-12	Pathways in cancer: MYC**
hsa05014__13	4.11004220774009e-13	UP	7.25235500149135	1.15783647801254e-12	Amyotrophic lateral sclerosis (ALS): CASP3
hsa04068__39	4.22519718989181e-13	UP	7.24861233344774	1.18849483829442e-12	FoxO signaling pathway: CCNB3
hsa04660__43	4.52712592754082e-13	DOWN	-7.23925566333874	1.26962233102227e-12	T cell receptor signaling pathway: RHOA
hsa04662__36	4.52712592754082e-13	UP	7.23925566333874	1.26962233102227e-12	B cell receptor signaling pathway: CD79A
hsa04390__12	4.65374249856215e-13	DOWN	-7.23551299529513	1.29931384172337e-12	Hippo signaling pathway: CTGF
hsa04950__8	4.65374249856215e-13	UP	7.23551299529513	1.29931384172337e-12	Maturity onset diabetes of the young: NEUROD1
hsa05032__37	4.65374249856215e-13	DOWN	-7.23551299529513	1.29931384172337e-12	Morphine addiction: KCNJ3
hsa04725__64	4.88374036652641e-13	DOWN	-7.22896332621883	1.36150566004497e-12	Cholinergic synapse: KCNJ3
hsa05200__193	5.16027984966351e-13	DOWN	-7.22147799013162	1.43646901296559e-12	Pathways in cancer: NOS2
hsa04015__100 101 48	5.45217802955903e-13	DOWN	-7.21399265404442	1.5154796623582e-12	Rap1 signaling pathway: PRKCI PARD6A PARD3
hsa04530__14 20 43	5.52764934901216e-13	DOWN	-7.21212132002262	1.5341880541793e-12	Tight junction: CTNNA1 ACTB ACTN4
hsa05161__188	6.34107454347353e-13	UP	7.1934079798046	1.75735679457032e-12	Hepatitis B: IFNB1
hsa04024__25	6.51732532220823e-13	DOWN	-7.189665311761	1.80354260389238e-12	cAMP signaling pathway: CFTR
hsa05161__44	6.97926360759391e-13	UP	7.18030864165199	1.92853475274543e-12	Hepatitis B: CXCL8
hsa05020__59	8.22306397762733e-13	DOWN	-7.15785263339037	2.26888945873154e-12	Prion diseases: CCL5
hsa04919__101	8.50834191370739e-13	DOWN	-7.15317429833587	2.34416047739827e-12	Thyroid hormone signaling pathway: NOTCH1
hsa05133__96	8.56655221531962e-13	DOWN	-7.15223863132497	2.35674254942688e-12	Pertussis: IL1B
hsa04666__51	9.74982030966742e-13	DOWN	-7.13446095811786	2.67834976050659e-12	Fc gamma R-mediated phagocytosis: NCF1
hsa05205__318	1.0435575976669e-12	DOWN	-7.12510428800885	2.86254704527897e-12	Proteoglycans in cancer: HSPB2
hsa04010__68	1.06503795489052e-12	UP	7.12229728697615	2.91721037498439e-12	MAPK signaling pathway: ATF2
hsa04066__5	1.16324297916504e-12	DOWN	-7.11013361583444	3.17693831083011e-12	HIF-1 signaling pathway: VEGFA
hsa04360__122	1.16324297916504e-12	DOWN	-7.11013361583444	3.17693831083011e-12	Axon guidance: CFL1**
hsa03320__66	1.42503829860061e-12	DOWN	-7.08206360550742	3.88628006251168e-12	PPAR signaling pathway: UCP1
hsa04068__49	1.44441390220912e-12	DOWN	-7.08019227148562	3.93341119166803e-12	FoxO signaling pathway: BCL2L11
hsa04810__31	1.65295391634358e-12	DOWN	-7.0614789312676	4.49479075080982e-12	Regulation of actin cytoskeleton: MSN
hsa05166__26	1.8408079504336e-12	DOWN	-7.04650825909319	4.99837881338834e-12	HTLV-I infection: NFATC1
hsa04611__25	2.09120822677694e-12	DOWN	-7.02873058588608	5.6701013825597e-12	Platelet activation: ORAI1
hsa04620__76	2.14803278242351e-12	DOWN	-7.02498791784248	5.81578328267115e-12	Toll-like receptor signaling pathway: CCL3L3
hsa04924__58	2.1624739197407e-12	DOWN	-7.02405225083157	5.83805818274823e-12	Renin secretion: PPP3CA
hsa05031__59	2.1624739197407e-12	DOWN	-7.02405225083157	5.83805818274823e-12	Amphetamine addiction: PPP3CA
hsa05200__65	2.22119679692862e-12	DOWN	-7.02030958278797	5.98798964336998e-12	Pathways in cancer: STK4
hsa05200__5	2.29680348961035e-12	DOWN	-7.01563124773347	6.17409693416e-12	Pathways in cancer: CASP3*
hsa05210__7	2.29680348961035e-12	DOWN	-7.01563124773347	6.17409693416e-12	Colorectal cancer: CASP3*
hsa05166__114 112 113	2.62529263668076e-12	DOWN	-6.99691790751545	7.04703552046163e-12	HTLV-I infection: DLG1 CTNNB1 APC2
hsa05200__207	2.67838451052497e-12	DOWN	-6.99411090648275	7.17929314590073e-12	Pathways in cancer: CDK4
hsa04726__72	2.76922004568204e-12	DOWN	-6.98943257142825	7.41220009378426e-12	Serotonergic synapse: KCNJ3
hsa04068__88	3.06023731172543e-12	DOWN	-6.97539756626474	8.17949631398589e-12	FoxO signaling pathway: FBXO32
hsa04340__46	3.20611133075275e-12	DOWN	-6.96884789718843	8.55722044102901e-12	Hedgehog signaling pathway: PRKACA
hsa04530__30	3.68586441598575e-12	UP	6.94919888995952	9.82374359948542e-12	Tight junction: AKT3
hsa05030__76	4.15257600347314e-12	DOWN	-6.93235688376331	1.10519692783655e-11	Cocaine addiction: PDYN
hsa04727__47	4.18013794287859e-12	DOWN	-6.93142121675241	1.11095886770423e-11	GABAergic synapse: CACNA1A*
hsa04211__42	4.29219037626584e-12	DOWN	-6.9276785487088	1.13912792613044e-11	Longevity regulating pathway - mammal: PPARGC1A
hsa05032__25	4.58536344397154e-12	DOWN	-6.9183218785998	1.21521832316256e-11	Morphine addiction: C00575*
hsa04925__33	4.61573844236472e-12	DOWN	-6.91738621158889	1.22154542721173e-11	Aldosterone synthesis and secretion: CYP11B2
hsa04920__40	4.80217425390782e-12	DOWN	-6.91177220952349	1.26909780915511e-11	Adipocytokine signaling pathway: PPARGC1A
hsa03320__37	4.89814051866613e-12	DOWN	-6.90896520849079	1.29264129699068e-11	PPAR signaling pathway: HMGCS2
hsa05211__2	4.9305450986781e-12	DOWN	-6.90802954147989	1.29936805615935e-11	Renal cell carcinoma: TGFB1
hsa04064__94	5.44258971295617e-12	DOWN	-6.89399453631638	1.4323005701183e-11	NF-kappa B signaling pathway: BCL2L1*
hsa04960__13	5.51468455574213e-12	DOWN	-6.89212320229458	1.44924367555797e-11	Aldosterone-regulated sodium reabsorption: FXYD4
hsa04910__9	5.6990418263613e-12	UP	6.88744486724007	1.49351458741044e-11	Insulin signaling pathway: ELK1
hsa05169__32	5.6990418263613e-12	UP	6.88744486724007	1.49351458741044e-11	Epstein-Barr virus infection: CR2
hsa04024__21	5.73663157425944e-12	DOWN	-6.88650920022917	1.50127168914115e-11	cAMP signaling pathway: AKT3
hsa04710__7	6.04622695944389e-12	DOWN	-6.87902386414197	1.58009185769055e-11	Circadian rhythm: PER1
hsa04350__21	6.0860596205024e-12	DOWN	-6.87808819713107	1.58829250373944e-11	TGF-beta signaling pathway: CDKN2B
hsa04152__82	6.20710705009096e-12	DOWN	-6.87528119609836	1.61763580403896e-11	AMPK signaling pathway: HMGCR
hsa05321__81	6.33051308856222e-12	DOWN	-6.87247419506566	1.64751164728648e-11	Inflammatory bowel disease (IBD): IL13
hsa05152__82	6.41411629037349e-12	DOWN	-6.87060286104386	1.666960513086e-11	Tuberculosis: IL6
hsa04014__54	6.4988012600437e-12	DOWN	-6.86873152702206	1.6866364043677e-11	Ras signaling pathway: RHOA
hsa04917__37	6.75948459491457e-12	UP	6.86311752495665	1.75187193846131e-11	Prolactin signaling pathway: TNFSF11
hsa05152__120	6.84863531022349e-12	DOWN	-6.86124619093485	1.7725324721639e-11	Tuberculosis: TGFB1
hsa04520__64	7.45685416457734e-12	DOWN	-6.84908251979314	1.92464683725835e-11	Adherens junction: CTNND1**
hsa04916__6	7.45685416457734e-12	DOWN	-6.84908251979314	1.92464683725835e-11	Melanogenesis: DCT
hsa04922__50	8.27843072996058e-12	DOWN	-6.83411184761873	2.13376835961535e-11	Glucagon signaling pathway: PCK1
hsa04024__59	8.60885794897004e-12	DOWN	-6.82849784555333	2.2158964501527e-11	cAMP signaling pathway: MLLT4
hsa04340__17	8.66517138475443e-12	UP	6.82756217854243	2.22734022324946e-11	Hedgehog signaling pathway: SMO
hsa04360__40 142	9.93470383395947e-12	DOWN	-6.80791317131351	2.55017875737839e-11	Axon guidance: UNC5D PTPN11
hsa05132__86	1.26291107224242e-11	DOWN	-6.77329349191019	3.23739414016851e-11	Salmonella infection: MYH9
hsa05210__9 11	1.28765789334382e-11	DOWN	-6.77048649087748	3.2963340348679e-11	Colorectal cancer: SMAD2 SMAD4
hsa04390__5	1.33858475610186e-11	UP	6.76487248881208	3.42204184587129e-11	Hippo signaling pathway: SAV1
hsa05164__20	1.48423022895575e-11	DOWN	-6.74990181663767	3.78922364158675e-11	Influenza A: ATF2
hsa04310__31	1.55272840548125e-11	UP	6.74335214756136	3.95872004599629e-11	Wnt signaling pathway: MMP7
hsa04520__73	1.59325025599365e-11	UP	6.73960947951776	4.05652741329548e-11	Adherens junction: PARD3
hsa04728__61	1.64536112881583e-11	DOWN	-6.73493114446326	4.18353661846406e-11	Dopaminergic synapse: KCNJ3
hsa04520__44 49	1.66666961554515e-11	DOWN	-6.73305981044146	4.23198946974235e-11	Adherens junction: ACTB VCL
hsa05030__69	1.73222948525004e-11	DOWN	-6.72744580837605	4.39252254087021e-11	Cocaine addiction: PRKACA**
hsa04520__34	1.88304093609397e-11	DOWN	-6.71528213723434	4.76850932469079e-11	Adherens junction: RHOA
hsa04062__33	1.89517955077389e-11	DOWN	-6.71434647022344	4.79278920040935e-11	Chemokine signaling pathway: WAS
hsa04010__63	1.91965085070727e-11	UP	6.71247513620164	4.84815046838571e-11	MAPK signaling pathway: MAX
hsa05016__48	2.26736308097215e-11	DOWN	-6.68814779391822	5.71095875220734e-11	Huntington's disease: HIP1
hsa05016__46	2.26736308097215e-11	DOWN	-6.68814779391822	5.71095875220734e-11	Huntington's disease: HTT**
hsa04310__13	2.35596935293159e-11	DOWN	-6.68253379185282	5.92619332551333e-11	Wnt signaling pathway: NFATC1
hsa05205__145	2.37104083939824e-11	DOWN	-6.68159812484192	5.95613066474505e-11	Proteoglycans in cancer: PXN
hsa05134__68	2.54346942220953e-11	DOWN	-6.67130578772201	6.38074638762579e-11	Legionellosis: TNF
hsa04660__34	2.60915706953297e-11	DOWN	-6.66756311967841	6.53680817820326e-11	T cell receptor signaling pathway: FOS
hsa04014__63	2.65950976254046e-11	DOWN	-6.66475611864571	6.65408634329365e-11	Ras signaling pathway: TIAM1*
hsa04668__40	2.763085077311e-11	DOWN	-6.6591421165803	6.90403837801512e-11	TNF signaling pathway: JUN
hsa05020__49	2.96332517009987e-11	UP	6.64884977946039	7.39453916947896e-11	Prion diseases: BAX
hsa05012__70	3.02035727113232e-11	DOWN	-6.64604277842769	7.52685850458571e-11	Parkinson's disease: PRKACA
hsa04728__44	3.03960564071419e-11	DOWN	-6.64510711141679	7.56479337602909e-11	Dopaminergic synapse: FOS
hsa04971__39	3.07846324092035e-11	DOWN	-6.64323577739499	7.65136564773721e-11	Gastric acid secretion: EZR
hsa04115__22	3.17774671100626e-11	UP	6.63855744234049	7.88769626153338e-11	p53 signaling pathway: STEAP3
hsa04727__49	3.45077849099779e-11	UP	6.62639377119878	8.55410657596945e-11	GABAergic synapse: GABRR3
hsa05215__8	4.47102514815176e-11	DOWN	-6.58803142375185	1.10685853140674e-10	Prostate cancer: NFKBIA
hsa05031__101	4.49927915658485e-11	DOWN	-6.58709575674095	1.11238757042407e-10	Amphetamine addiction: FOS*
hsa03320__39	4.61405240868168e-11	UP	6.58335308869734	1.13926471431181e-10	PPAR signaling pathway: MMP1
hsa04530__20 31	4.67250828461421e-11	DOWN	-6.58148175467554	1.15218412950001e-10	Tight junction: ACTB MLLT4
hsa05168__123	4.70200730879304e-11	UP	6.58054608766464	1.15793862820736e-10	Herpes simplex infection: CYCS
hsa04920__37	5.13463136654003e-11	UP	6.56744674951203	1.26282360441475e-10	Adipocytokine signaling pathway: IRS1
hsa04340__14	5.26523267013046e-11	DOWN	-6.56370408146843	1.2932512662974e-10	Hedgehog signaling pathway: PTCH1
hsa04740__42	5.46724884539219e-11	DOWN	-6.55809007940302	1.34111756925482e-10	Olfactory transduction: PDE2A
hsa05160__71	5.7125285472534e-11	UP	6.55154041032672	1.39945777578737e-10	Hepatitis C: MAPK8
hsa05219__21	5.93130982233563e-11	UP	6.54592640826132	1.45116291095946e-10	Bladder cancer: RB1
hsa04550__25	6.15827999440491e-11	UP	6.54031240619591	1.50473447457566e-10	Signaling pathways regulating pluripotency of stem cells: MAPK1
hsa05012__71	6.31429009266259e-11	DOWN	-6.53656973815231	1.54085079014455e-10	Parkinson's disease: PRKACA*
hsa05164__65 66	6.43382798478628e-11	UP	6.53376273711961	1.56798479681108e-10	Influenza A: DNAJC3 HSPA1A
hsa05205__324	6.63799401399017e-11	DOWN	-6.5290844020651	1.61564647050357e-10	Proteoglycans in cancer: KDR*
hsa04064__133	6.89136832132167e-11	DOWN	-6.5234703999997	1.6751463228672e-10	NF-kappa B signaling pathway: CXCL2
hsa05217__4	7.06551385819414e-11	DOWN	-6.5197277319561	1.7152584676417e-10	Basal cell carcinoma: PTCH1
hsa04152__49	7.15419319338947e-11	UP	6.51785639793429	1.73454567875856e-10	AMPK signaling pathway: GYS1
hsa04014__38	7.24396070245708e-11	DOWN	-6.51598506391249	1.75404667009238e-10	Ras signaling pathway: MAPK8
hsa04151__34	7.42681253292141e-11	UP	6.51224239586889	1.79600781845036e-10	PI3K-Akt signaling pathway: GYS1
hsa04066__60	7.66173372596451e-11	DOWN	-6.50756406081439	1.85043671864876e-10	HIF-1 signaling pathway: NOS3
hsa04010__61	8.00287158020334e-11	UP	6.50101439173808	1.93034604611067e-10	MAPK signaling pathway: ATF4
hsa05100__33	8.67625590360546e-11	UP	6.48885072059637	2.09008780036855e-10	Bacterial invasion of epithelial cells: DNM1
hsa05030__37	8.89437720077954e-11	DOWN	-6.48510805255277	2.13988921386232e-10	Cocaine addiction: PRKACA
hsa05220__21	9.11785702644457e-11	DOWN	-6.48136538450917	2.19085081236437e-10	Chronic myeloid leukemia: NFKBIA
hsa05140__21	9.52222867547722e-11	DOWN	-6.47481571543286	2.28509165788272e-10	Leishmaniasis: NFKB1
hsa04068__48	1.08434294944688e-10	DOWN	-6.45516670820395	2.59882704338099e-10	FoxO signaling pathway: FASLG
hsa05205__238	1.35368809560866e-10	UP	6.42148269581152	3.24022921229129e-10	Proteoglycans in cancer: ITGAV*
hsa05150__69	1.59759275782444e-10	DOWN	-6.3962196865172	3.81918166915029e-10	Staphylococcus aureus infection: FPR2
hsa04390__77	1.78352983756182e-10	DOWN	-6.37937768032099	4.25826247112917e-10	Hippo signaling pathway: CCND1
hsa05152__126	1.79445757354578e-10	DOWN	-6.37844201331009	4.27891596534584e-10	Tuberculosis: NOS2
hsa05134__10	1.87280468322603e-10	DOWN	-6.37189234423379	4.46007604535071e-10	Legionellosis: NFKB1
hsa04210__75	2.03965346206371e-10	UP	6.35879300608118	4.85127703192116e-10	Apoptosis: BAK1*
hsa05213__29	2.07725190388944e-10	DOWN	-6.35598600504847	4.93445806246303e-10	Endometrial cancer: CCND1
hsa05321__95	2.14142576850051e-10	DOWN	-6.35130766999397	5.08047855935917e-10	Inflammatory bowel disease (IBD): SMAD2
hsa05211__22	2.16763404849435e-10	UP	6.34943633597217	5.13617197619279e-10	Renal cell carcinoma: TGFA
hsa04622__21 22 23	2.22099397429554e-10	UP	6.34569366792857	5.25597944294877e-10	RIG-I-like receptor signaling pathway: CHUK IKBKB IKBKG
hsa04071__68	2.36007000255066e-10	DOWN	-6.33633699781956	5.57807740225496e-10	Sphingolipid signaling pathway: NFKB1
hsa04915__58	2.47742268542098e-10	UP	6.32885166173235	5.84808696721861e-10	Estrogen signaling pathway: CREB3***
hsa05321__74	2.58476703987538e-10	DOWN	-6.32230199265605	6.09382342274257e-10	Inflammatory bowel disease (IBD): IL5
hsa05215__43	2.63210168571631e-10	DOWN	-6.31949499162335	6.19764294168039e-10	Prostate cancer: C05981
hsa04014__55	2.86472526769515e-10	DOWN	-6.30639565347074	6.73694465331563e-10	Ras signaling pathway: MLLT4
hsa05160__58	2.88208498712683e-10	UP	6.30545998645984	6.76929711351415e-10	Hepatitis C: EIF3E
hsa05219__10	2.97043619344825e-10	UP	6.30078165140533	6.96810188200907e-10	Bladder cancer: EGFR
hsa05205__195	3.00651242471084e-10	DOWN	-6.29891031738353	7.0439362169971e-10	Proteoglycans in cancer: CDKN1A
hsa04620__40	3.27130308727498e-10	DOWN	-6.28581097923092	7.65476774718515e-10	Toll-like receptor signaling pathway: CCL5
hsa05216__14	3.47424383565301e-10	UP	6.27645430912191	8.1195325462587e-10	Thyroid cancer: MAPK1*
hsa05213__27	3.58027272246861e-10	UP	6.27177597406741	8.35693471492983e-10	Endometrial cancer: ELK1
hsa04024__3	3.68945849878506e-10	DOWN	-6.26709763901291	8.60110734394185e-10	cAMP signaling pathway: RYR2
hsa04115__15	3.73403715562553e-10	UP	6.2652263049911	8.69424512443664e-10	p53 signaling pathway: TSC2
hsa04152__94	3.8247775822507e-10	DOWN	-6.2614836369475	8.89450133298152e-10	AMPK signaling pathway: MLYCD
hsa04922__59	3.96493761125681e-10	DOWN	-6.2558696348821	9.19767626117474e-10	Glucagon signaling pathway: CPT1C
hsa05162__93	3.96493761125681e-10	UP	6.2558696348821	9.19767626117474e-10	Measles: TP53
hsa04012__23	4.28603609400484e-10	DOWN	-6.24370596374039	9.93028584541934e-10	ErbB signaling pathway: RPS6KB1
hsa04213__53	4.3117613916056e-10	DOWN	-6.24277029672949	9.97758578180655e-10	Longevity regulating pathway - multiple species: SOD1
hsa05152__78	4.57744600491137e-10	DOWN	-6.23341362662048	1.05793616767878e-09	Tuberculosis: IL1A
hsa04620__46	4.63246846953517e-10	DOWN	-6.23154229259868	1.06933762337304e-09	Toll-like receptor signaling pathway: TNF
hsa04810__21 82	4.71621447965328e-10	DOWN	-6.22873529156598	1.08733337512497e-09	Regulation of actin cytoskeleton: CFL1 ACTB
hsa04950__20	5.25060993408922e-10	UP	6.21189328536977	1.20905589046001e-09	Maturity onset diabetes of the young: NKX6-1
hsa04919__29	5.31351488884295e-10	DOWN	-6.21002195134796	1.22204338753193e-09	Thyroid hormone signaling pathway: HIF1A
hsa04115__36	5.34524255598026e-10	UP	6.20908628433706	1.22783750155097e-09	p53 signaling pathway: EI24
hsa04024__110	5.57257113223896e-10	DOWN	-6.20253661526076	1.27849342582137e-09	cAMP signaling pathway: FOS
hsa04931__13	5.80932422521787e-10	DOWN	-6.19598694618445	1.33118539258346e-09	Insulin resistance: AKT2
hsa04210__60	5.98441368042236e-10	UP	6.19130861112995	1.36963621260824e-09	Apoptosis: BBC3
hsa04931__137	6.35017540959477e-10	UP	6.18195194102094	1.45157902611053e-09	Insulin resistance: MLXIP*
hsa04360__114	6.50250903267033e-10	DOWN	-6.17820927297734	1.4845947111042e-09	Axon guidance: RAF1
hsa04072__36	6.85841126495527e-10	UP	6.16978826987923	1.56395082121978e-09	Phospholipase D signaling pathway: MTOR
hsa04919__102	7.27615906570855e-10	DOWN	-6.16043159977023	1.65720034963229e-09	Thyroid hormone signaling pathway: BMP4
hsa04390__88	7.53861473216508e-10	DOWN	-6.15481759770482	1.71489795178428e-09	Hippo signaling pathway: ID1
hsa05110__13	7.62811063447492e-10	DOWN	-6.15294626368302	1.73315838962254e-09	Vibrio cholerae infection: C00238
hsa05100__15	7.8102968285922e-10	UP	6.14920359563942	1.77240914745468e-09	Bacterial invasion of epithelial cells: CTNNA1
hsa04910__20	7.85649619275318e-10	UP	6.14826792862852	1.78074262318254e-09	Insulin signaling pathway: PKLR
hsa04923__38	7.9966993883978e-10	DOWN	-6.14546092759582	1.81033712660235e-09	Regulation of lipolysis in adipocytes: PDE3B
hsa04610__11	8.04397383722832e-10	UP	6.14452526058491	1.81884799520481e-09	Complement and coagulation cascades: F2R
hsa03320__27	8.13934192525732e-10	DOWN	-6.14265392656311	1.83819993720655e-09	PPAR signaling pathway: CPT1C
hsa04210__69	8.18743863179176e-10	DOWN	-6.14171825955221	1.84684239965627e-09	Apoptosis: PTPN13
hsa04921__54	8.53196391344991e-10	DOWN	-6.13516859047591	1.92224942366575e-09	Oxytocin signaling pathway: RCAN1
hsa05031__11	8.68390922232776e-10	UP	6.1323615894432	1.95180208477917e-09	Amphetamine addiction: GRIN3A
hsa05031__54	8.68390922232776e-10	UP	6.1323615894432	1.95180208477917e-09	Amphetamine addiction: GRIN3A*
hsa04530__8	9.26395236785759e-10	DOWN	-6.1220692523233	2.0796853643016e-09	Tight junction: LLGL2
hsa04910__17	9.31851924754594e-10	DOWN	-6.1211335853124	2.08943886230774e-09	Insulin signaling pathway: C00031
hsa04740__33	9.42859494609506e-10	UP	6.1192622512906	2.11160070366062e-09	Olfactory transduction: CNGA3*
hsa05205__45 46	9.93982915056408e-10	UP	6.11084124819249	2.22344511594166e-09	Proteoglycans in cancer: PAK1 FLNA
hsa05164__68	1.02354251913123e-09	UP	6.10616291313799	2.28684470088891e-09	Influenza A: EIF2S1
hsa04012__37 7	1.03560485175026e-09	DOWN	-6.10429157911618	2.31104693163746e-09	ErbB signaling pathway: ERBB3 ERBB3
hsa04724__5 71	1.05395865148731e-09	UP	6.10148457808348	2.3492150725322e-09	Glutamatergic synapse: GRIN3A DLG4
hsa04922__51	1.29296698190592e-09	DOWN	-6.06873623270196	2.87513012899554e-09	Glucagon signaling pathway: G6PC
hsa05231__39	1.29296698190592e-09	UP	6.06873623270196	2.87513012899554e-09	Choline metabolism in cancer: EIF4EBP1
hsa04014__41	1.32343591084504e-09	DOWN	-6.06499356465835	2.93940434571848e-09	Ras signaling pathway: RAC1*
hsa04210__72	1.33893171096716e-09	DOWN	-6.06312223063655	2.96680741144728e-09	Apoptosis: BCL2A1
hsa04919__99	1.33893171096716e-09	DOWN	-6.06312223063655	2.96680741144728e-09	Thyroid hormone signaling pathway: WNT4
hsa04916__8	1.36250753229422e-09	DOWN	-6.06031522960385	3.0154907575746e-09	Melanogenesis: TYR*
hsa03320__36	1.37045568726022e-09	DOWN	-6.05937956259295	3.02951321924935e-09	PPAR signaling pathway: SLC27A4
hsa04071__89	1.52149685242328e-09	DOWN	-6.04253755639674	3.35945074700744e-09	Sphingolipid signaling pathway: C00533
hsa04932__138	1.73826062822095e-09	DOWN	-6.02101721514602	3.83355835730888e-09	Non-alcoholic fatty liver disease (NAFLD): CEBPA
hsa04670__14	1.74833796705625e-09	UP	6.02008154813512	3.85126264958815e-09	Leukocyte transendothelial migration: SIPA1
hsa05160__56	1.7789127511908e-09	UP	6.01727454710242	3.90944685320178e-09	Hepatitis C: MAPK1
hsa05166__32	1.7789127511908e-09	DOWN	-6.01727454710242	3.90944685320178e-09	HTLV-I infection: STAT5A
hsa04152__60	1.82049069975515e-09	UP	6.01353187905882	3.9961472252803e-09	AMPK signaling pathway: EEF2
hsa05161__194	1.8416332445126e-09	DOWN	-6.01166054503701	4.03783998417639e-09	Hepatitis B: TNF*
hsa04024__111	1.87379633375765e-09	DOWN	-6.00885354400431	4.10357029269303e-09	cAMP signaling pathway: JUN
hsa04750__60	2.00798904762428e-09	UP	5.9976255398735	4.39232994235857e-09	Inflammatory mediator regulation of TRP channels: TRPV3
hsa04071__11	2.05479539600947e-09	DOWN	-5.9938828718299	4.48948901058349e-09	Sphingolipid signaling pathway: PRKCA
hsa04921__41	2.15157287102607e-09	DOWN	-5.9863975357427	4.69547668369105e-09	Oxytocin signaling pathway: PTGS2
hsa04064__55	2.37219615625812e-09	DOWN	-5.97049119655738	5.17094730581091e-09	NF-kappa B signaling pathway: CXCL12
hsa04015__17	2.39955738858407e-09	DOWN	-5.96861986253558	5.22452877537597e-09	Rap1 signaling pathway: ACTB
hsa04071__48	2.46929928932551e-09	DOWN	-5.96394152748108	5.37015435722527e-09	Sphingolipid signaling pathway: SMPD1
hsa05169__83	2.49776373542608e-09	DOWN	-5.96207019345928	5.4257781027348e-09	Epstein-Barr virus infection: GSK3B
hsa04390__89	2.51210896853491e-09	DOWN	-5.96113452644838	5.45063828161328e-09	Hippo signaling pathway: ID2
hsa03320__63	2.59988053255722e-09	DOWN	-5.95552052438297	5.63457384160901e-09	PPAR signaling pathway: DBI
hsa04380__16	2.7371634289653e-09	DOWN	-5.94709952128487	5.92526507261036e-09	Osteoclast differentiation: NFKB1
hsa04914__29	2.9817848392234e-09	UP	5.93306451612136	6.44738056720456e-09	Progesterone-mediated oocyte maturation: CDK2
hsa04380__32	3.01599339643796e-09	DOWN	-5.93119318209955	6.51385240449073e-09	Osteoclast differentiation: AKT3
hsa05145__33	3.12085854184427e-09	DOWN	-5.92557918003415	6.72487752307958e-09	Toxoplasmosis: STAT3
hsa05169__125	3.12085854184427e-09	DOWN	-5.92557918003415	6.72487752307958e-09	Epstein-Barr virus infection: STAT3
hsa05134__72	3.32240714273938e-09	DOWN	-5.91528684291424	7.15097711478499e-09	Legionellosis: IL12A
hsa04152__68	3.39879455628518e-09	DOWN	-5.91154417487064	7.30701941791745e-09	AMPK signaling pathway: PPARGC1A**
hsa05152__69	3.43762674842333e-09	DOWN	-5.90967284084884	7.38205789747135e-09	Tuberculosis: HLA-DMA
hsa05231__59	3.67985245068933e-09	DOWN	-5.89844483671803	7.89319949183249e-09	Choline metabolism in cancer: PLA2G4B
hsa05161__125	3.98348527861648e-09	DOWN	-5.88534549856542	8.53474211917943e-09	Hepatitis B: CDKN1A
hsa05161__207	4.31145000755525e-09	UP	5.87224616041281	9.21639882161128e-09	Hepatitis B: CDK2
hsa05161__219	4.31145000755525e-09	UP	5.87224616041281	9.21639882161128e-09	Hepatitis B: CDK2*
hsa04261__8 38	4.45991809529404e-09	DOWN	-5.86663215834741	9.52293875120171e-09	Adrenergic signaling in cardiomyocytes: ATP2A2 PLN
hsa05200__173	4.53600623110331e-09	DOWN	-5.8638251573147	9.66344184608063e-09	Pathways in cancer: CCNA1
hsa05221__16	4.53600623110331e-09	DOWN	-5.8638251573147	9.66344184608063e-09	Acute myeloid leukemia: CCNA1
hsa04724__66	4.63942471285861e-09	DOWN	-5.8600824892711	9.87256968908417e-09	Glutamatergic synapse: PLA2G4B
hsa04261__14 16	4.77192821489413e-09	DOWN	-5.8554041542166	1.01430465110702e-08	Adrenergic signaling in cardiomyocytes: TNNI3 TPM1
hsa05223__24	4.99162853014827e-09	DOWN	-5.84791881812939	1.05980452069476e-08	Non-small cell lung cancer: STK4
hsa04022__19	5.33974247334691e-09	UP	5.83669081399858	1.13243522657098e-08	cGMP-PKG signaling pathway: CNGB1
hsa05168__29	5.49166135834985e-09	UP	5.83201247894408	1.16334066429982e-08	Herpes simplex infection: IKBKG
hsa04115__24	5.71143177568586e-09	UP	5.82546280986777	1.2085338183011e-08	p53 signaling pathway: SERPINB5
hsa04722__84	5.8408317200494e-09	DOWN	-5.82172014182417	1.23452449965948e-08	Neurotrophin signaling pathway: NFKB1*
hsa04722__50	6.75418917735695e-09	UP	5.79739279954075	1.42596870384873e-08	Neurotrophin signaling pathway: RHOA
hsa04623__8	7.02293238251401e-09	UP	5.79084313046445	1.47938228102509e-08	Cytosolic DNA-sensing pathway: TBK1
hsa05205__22	7.02293238251401e-09	DOWN	-5.79084313046445	1.47938228102509e-08	Proteoglycans in cancer: PPP1R12A
hsa04620__86	7.38377715930993e-09	DOWN	-5.78242212736634	1.55365255121426e-08	Toll-like receptor signaling pathway: IL12A
hsa04921__80	7.50801751654273e-09	DOWN	-5.77961512633364	1.57802739525546e-08	Oxytocin signaling pathway: KCNJ2
hsa04066__26	7.59197125973374e-09	DOWN	-5.77774379231184	1.59388983207148e-08	HIF-1 signaling pathway: C01245
hsa04014__24	7.93700857021256e-09	DOWN	-5.77025845622463	1.66446864993632e-08	Ras signaling pathway: PLD1
hsa04960__4	8.38978377854132e-09	DOWN	-5.76090178611563	1.75745860868218e-08	Aldosterone-regulated sodium reabsorption: ATP1B4
hsa04610__44	9.06612040232985e-09	DOWN	-5.74780244796302	1.89702007082158e-08	Complement and coagulation cascades: C3
hsa05164__23	9.16696495836478e-09	UP	5.74593111394122	1.91598744791629e-08	Influenza A: IRF3
hsa04723__10	9.58135896856124e-09	UP	5.73844577785401	1.99815466170106e-08	Retrograde endocannabinoid signaling: CACNA1A
hsa04723__21	9.58135896856124e-09	UP	5.73844577785401	1.99815466170106e-08	Retrograde endocannabinoid signaling: CACNA1A*
hsa04666__27	9.7953282199346e-09	DOWN	-5.73470310981041	2.04051238639214e-08	Fc gamma R-mediated phagocytosis: ARPC5
hsa04022__59	1.0125015680728e-08	DOWN	-5.729089107745	2.10685542237961e-08	cGMP-PKG signaling pathway: NPPB
hsa04919__84	1.01810020973532e-08	UP	5.7281534407341	2.11616182974852e-08	Thyroid hormone signaling pathway: TP53*
hsa04115__19	1.04079719560428e-08	UP	5.7244107726905	2.16094798954745e-08	p53 signaling pathway: RFWD2
hsa04670__45	1.05232935339934e-08	DOWN	-5.7225394386687	2.18247997244742e-08	Leukocyte transendothelial migration: PXN
hsa04728__68	1.09971248996336e-08	DOWN	-5.71505410258149	2.27823568758671e-08	Dopaminergic synapse: CACNA1C
hsa05200__192	1.11801041688966e-08	DOWN	-5.71224710154879	2.31359204111857e-08	Pathways in cancer: PTGS2
hsa05034__62	1.20738660256665e-08	DOWN	-5.69914776339618	2.49579694853986e-08	Alcoholism: NPY
hsa05031__8	1.30367830113407e-08	DOWN	-5.68604842524357	2.6918807998142e-08	Amphetamine addiction: DRD1
hsa04921__59	1.33254911986678e-08	DOWN	-5.68230575719997	2.7484739804936e-08	Oxytocin signaling pathway: CCND1
hsa05014__33 34	1.51919137147392e-08	DOWN	-5.65984974893835	3.1300006436398e-08	Amyotrophic lateral sclerosis (ALS): NEFH PRPH
hsa04666__30 44	1.5696813090736e-08	DOWN	-5.65423574687295	3.23048321987875e-08	Fc gamma R-mediated phagocytosis: C04637 GSN
hsa05205__140	1.83760505976169e-08	DOWN	-5.62710140355683	3.7777460692475e-08	Proteoglycans in cancer: MAPK1***
hsa05164__77	1.84759445884037e-08	UP	5.62616573654593	3.79413113460225e-08	Influenza A: CASP9
hsa04360__19	2.05882015990764e-08	UP	5.60745239632791	4.22327847212496e-08	Axon guidance: CDC42
hsa05221__6	2.14971892409168e-08	DOWN	-5.59996706024071	4.40493114325873e-08	Acute myeloid leukemia: CEBPA
hsa05014__31 34	2.2324416515987e-08	DOWN	-5.5934173911644	4.5694530101895e-08	Amyotrophic lateral sclerosis (ALS): NEFL PRPH
hsa04064__116	2.26883268241697e-08	DOWN	-5.5906103901317	4.6388864094249e-08	NF-kappa B signaling pathway: GADD45B
hsa04610__46	2.40725786374165e-08	DOWN	-5.58031805301179	4.91656252822887e-08	Complement and coagulation cascades: C2
hsa05140__62	2.44641105945102e-08	DOWN	-5.57751105197909	4.99110356211559e-08	Leishmaniasis: C00584
hsa04210__74	2.45959894113565e-08	UP	5.57657538496819	5.00713587258275e-08	Apoptosis: BAX*
hsa04919__27	2.45959894113565e-08	DOWN	-5.57657538496819	5.00713587258275e-08	Thyroid hormone signaling pathway: GATA4
hsa05321__19	2.58143650984251e-08	DOWN	-5.56815438187008	5.24947965583775e-08	Inflammatory bowel disease (IBD): TNF
hsa04380__20	2.72368250347599e-08	DOWN	-5.55879771176107	5.53275613408798e-08	Osteoclast differentiation: MAP2K1
hsa05200__146 147	2.87350335215495e-08	DOWN	-5.54944104165207	5.81822499859822e-08	Pathways in cancer: RARB RXRA
hsa05222__14 15	2.87350335215495e-08	DOWN	-5.54944104165207	5.81822499859822e-08	Small cell lung cancer: RXRA RARB
hsa05223__29 34	2.87350335215495e-08	DOWN	-5.54944104165207	5.81822499859822e-08	Non-small cell lung cancer: RARB RXRA
hsa04066__54	2.9672327567873e-08	DOWN	-5.54382703958666	6.00153966631146e-08	HIF-1 signaling pathway: SERPINE1
hsa05200__80	3.48206894305863e-08	UP	5.51575702925964	7.03527692903997e-08	Pathways in cancer: TP53
hsa04360__123	3.55694371629765e-08	UP	5.51201436121604	7.17883699562115e-08	Axon guidance: ENAH
hsa05205__30	3.57590502753442e-08	DOWN	-5.51107869420514	7.20936217461071e-08	Proteoglycans in cancer: FLNA
hsa05164__31 32 33	3.67215876149153e-08	DOWN	-5.50640035915063	7.39548372223214e-08	Influenza A: NLRP3 PYCARD CASP1
hsa04360__125	3.87236565685555e-08	UP	5.49704368904163	7.79033733322438e-08	Axon guidance: ENAH*
hsa04932__96	3.91365129391591e-08	DOWN	-5.49517235501983	7.86497409761283e-08	Non-alcoholic fatty liver disease (NAFLD): IL6*
hsa05166__99	4.56246592894851e-08	DOWN	-5.46803801170371	9.15905286377591e-08	HTLV-I infection: JUN
hsa04722__34	4.7590710271334e-08	DOWN	-5.4605526756165	9.54353731054819e-08	Neurotrophin signaling pathway: GSK3B
hsa05168__39 40	4.96387791370186e-08	UP	5.4530673395293	9.94363176955842e-08	Herpes simplex infection: POU2F3 HCFC2
hsa04370__25	5.06945972165379e-08	DOWN	-5.44932467148569	1.01443182289536e-07	VEGF signaling pathway: PXN
hsa05220__6	5.7201225609262e-08	UP	5.42780433023498	1.14341598850855e-07	Chronic myeloid leukemia: TP53
hsa04211__39	5.90274675199981e-08	UP	5.42219032816957	1.17866749702525e-07	Longevity regulating pathway - mammal: TP53*
hsa05205__91	5.99616496951717e-08	UP	5.41938332713687	1.19605031610645e-07	Proteoglycans in cancer: RAC1*
hsa04950__5	6.15505430807269e-08	DOWN	-5.41470499208237	1.22644189235086e-07	Maturity onset diabetes of the young: GCK
hsa04742__49	6.35111067496592e-08	UP	5.40909099001696	1.26416705066324e-07	Taste transduction: HTR1A
hsa04064__25	6.4851618958216e-08	UP	5.40534832197336	1.28948351346548e-07	NF-kappa B signaling pathway: NFKB2
hsa04622__9 35	6.58749503219553e-08	UP	5.40254132094066	1.30844642341389e-07	RIG-I-like receptor signaling pathway: IRF3 PIN1
hsa05220__50	6.7615362221919e-08	UP	5.39786298588615	1.34159731378021e-07	Chronic myeloid leukemia: MAPK1
hsa05200__194	7.12308029759409e-08	DOWN	-5.38850631577715	1.41184260328895e-07	Pathways in cancer: BCL2
hsa04310__33	7.3872295215006e-08	UP	5.38195664670084	1.46111623904207e-07	Wnt signaling pathway: CCND1
hsa05213__31	7.3872295215006e-08	DOWN	-5.38195664670084	1.46111623904207e-07	Endometrial cancer: MYC
hsa04922__78	7.42573118298291e-08	DOWN	-5.38102097968994	1.46718705497633e-07	Glucagon signaling pathway: ACACA
hsa05211__31	7.46442716618644e-08	DOWN	-5.38008531267904	1.47328347114121e-07	Renal cell carcinoma: SOS1
hsa04380__72	7.74082014194998e-08	DOWN	-5.37353564360274	1.52623305841805e-07	Osteoclast differentiation: MAPK1
hsa04015__27	7.94428514138814e-08	DOWN	-5.36885730854823	1.56470773382267e-07	Rap1 signaling pathway: RALA
hsa04670__76	8.28064529792708e-08	DOWN	-5.36137197246103	1.62924947799005e-07	Leukocyte transendothelial migration: CDC42
hsa04062__25	8.76573775784619e-08	DOWN	-5.35107963534112	1.72288925177751e-07	Chemokine signaling pathway: ROCK1
hsa04710__23	9.32630235681568e-08	UP	5.33985163121031	1.83115173756078e-07	Circadian rhythm: BHLHE41
hsa04151__101	9.47177648481127e-08	DOWN	-5.33704463017761	1.85777327922342e-07	PI3K-Akt signaling pathway: PKN3
hsa04350__11	9.66916283345778e-08	UP	5.333301962134	1.89451063233234e-07	TGF-beta signaling pathway: SMAD4*
hsa04380__69	9.87052839561438e-08	DOWN	-5.3295592940904	1.92993994332564e-07	Osteoclast differentiation: NFKB2
hsa05169__104	9.87052839561438e-08	UP	5.3295592940904	1.92993994332564e-07	Epstein-Barr virus infection: IRF3
hsa04064__135	1.02855079699053e-07	UP	5.3220739580032	2.00898851096175e-07	NF-kappa B signaling pathway: CCL19
hsa05210__23	1.06077738811061e-07	DOWN	-5.31645995593779	2.06978267109018e-07	Colorectal cancer: CCND1
hsa04071__1	1.09398024208501e-07	DOWN	-5.31084595387239	2.13235360464496e-07	Sphingolipid signaling pathway: MAPK1
hsa04360__82	1.14567756959179e-07	DOWN	-5.30242495077428	2.23080637643831e-07	Axon guidance: ILK
hsa04064__114	1.15748283439553e-07	DOWN	-5.30055361675248	2.25145988181077e-07	NF-kappa B signaling pathway: BCL2A1*
hsa04750__44	1.21206688692885e-07	UP	5.29213261365437	2.35276206667285e-07	Inflammatory mediator regulation of TRP channels: TRPA1
hsa04750__63	1.21206688692885e-07	UP	5.29213261365437	2.35276206667285e-07	Inflammatory mediator regulation of TRP channels: TRPA1*
hsa04151__33	1.23082543272778e-07	UP	5.28932561262167	2.38670896604283e-07	PI3K-Akt signaling pathway: TP53
hsa04066__62	1.24985213622241e-07	DOWN	-5.28651861158897	2.42110532367207e-07	HIF-1 signaling pathway: NPPA
hsa04015__30	1.2821973786002e-07	DOWN	-5.28184027653447	2.48120378412954e-07	Rap1 signaling pathway: ITGAL
hsa04666__50 52	1.32884442672492e-07	DOWN	-5.27529060745816	2.56882580022235e-07	Fc gamma R-mediated phagocytosis: DNM2 AMPH
hsa04024__101	1.3841663904996e-07	UP	5.26780527137096	2.67302019295864e-07	cAMP signaling pathway: HCN4
hsa04310__14	1.47134759284628e-07	DOWN	-5.25657726724015	2.83846214266752e-07	Wnt signaling pathway: PRKCA
hsa04310__20	1.54019486453417e-07	DOWN	-5.24815626414204	2.96823194918944e-07	Wnt signaling pathway: MAPK8
hsa04725__50	1.89527767200269e-07	DOWN	-5.20979391669511	3.64879789517731e-07	Cholinergic synapse: BCL2
hsa04012__29	2.16016324679069e-07	DOWN	-5.18546657441169	4.1545002463866e-07	ErbB signaling pathway: STAT5A*
hsa04310__36	2.18195877136203e-07	UP	5.18359524038989	4.19212733270885e-07	Wnt signaling pathway: MYC
hsa05152__90	2.21504594506417e-07	DOWN	-5.18078823935719	4.25134967392807e-07	Tuberculosis: CR1
hsa04530__22 33	2.23738133307683e-07	DOWN	-5.17891690533539	4.28983624984832e-07	Tight junction: MYL12B CGN
hsa04918__10	2.3172633465467e-07	UP	5.17236723625908	4.43846873410932e-07	Thyroid hormone synthesis: TG
hsa04950__22	2.42402565126373e-07	UP	5.16394623316098	4.63823238159322e-07	Maturity onset diabetes of the young: NR5A2
hsa04916__4	2.57379062740442e-07	DOWN	-5.15271822903017	4.91978900192564e-07	Melanogenesis: TYR
hsa04660__56	2.59960516653513e-07	DOWN	-5.15084689500837	4.96408344300763e-07	T cell receptor signaling pathway: CD3E
hsa05205__431	2.69194018132448e-07	DOWN	-5.14429722593206	5.1351833509733e-07	Proteoglycans in cancer: CDKN1A*
hsa04064__128	2.88620573586026e-07	DOWN	-5.13119788777945	5.50018314166473e-07	NF-kappa B signaling pathway: IL1B*
hsa04742__8	2.95880698998018e-07	DOWN	-5.12651955272495	5.63282505995214e-07	Taste transduction: PLCB2
hsa04728__74	3.15594442932094e-07	DOWN	-5.11435588158324	6.00204411203851e-07	Dopaminergic synapse: GRIN2A
hsa04550__101	3.21911005541486e-07	DOWN	-5.11061321353964	6.11598361387717e-07	Signaling pathways regulating pluripotency of stem cells: ESRRB
hsa05321__55	3.34912305314551e-07	DOWN	-5.10312787745243	6.35656789581861e-07	Inflammatory bowel disease (IBD): IL4*
hsa04152__24	3.62452394514634e-07	DOWN	-5.08815720527802	6.87233147621591e-07	AMPK signaling pathway: SIRT1
hsa04152__103	3.73333211508203e-07	UP	5.08254320321262	7.07150306878944e-07	AMPK signaling pathway: ULK1
hsa04810__30	3.8076150311375e-07	DOWN	-5.07880053516901	7.20494324623097e-07	Regulation of actin cytoskeleton: VCL*
hsa04115__20	3.86426118207822e-07	UP	5.07599353413631	7.30477541360661e-07	p53 signaling pathway: RRM2B
hsa04668__36	3.99961586284243e-07	UP	5.06944386506001	7.55304342339792e-07	TNF signaling pathway: CREB3
hsa05200__66	4.05901521901764e-07	DOWN	-5.0666368640273	7.65751967523508e-07	Pathways in cancer: CCND1
hsa04662__10	4.34765163969047e-07	DOWN	-5.0535375258747	8.18560864827495e-07	B cell receptor signaling pathway: GSK3B
hsa05211__49	4.34765163969047e-07	UP	5.0535375258747	8.18560864827495e-07	Renal cell carcinoma: TGFA*
hsa04919__91	4.5658392823406e-07	UP	5.04418085576569	8.58779981132932e-07	Thyroid hormone signaling pathway: PFKP
hsa05142__29	4.74795760443475e-07	DOWN	-5.03669551967848	8.92141233873289e-07	Chagas disease (American trypanosomiasis): NOS2
hsa05200__210	4.77120913397675e-07	DOWN	-5.03575985266758	8.95614581692538e-07	Pathways in cancer: MMP1
hsa05152__129	4.93707241199838e-07	UP	5.02921018359128	9.25824257699098e-07	Tuberculosis: IFNB1
hsa05168__138	5.41578559994312e-07	UP	5.01143251038416	1.01458236712793e-06	Herpes simplex infection: CHUK
hsa04610__52	5.82502999075887e-07	DOWN	-4.99739750522065	1.0901624853223e-06	Complement and coagulation cascades: CPB2
hsa04920__16	6.32489125303704e-07	DOWN	-4.98149116603534	1.18253439447329e-06	Adipocytokine signaling pathway: POMC
hsa04510__20 69	6.35554770068233e-07	DOWN	-4.98055549902444	1.18708490353699e-06	Focal adhesion: VASP ACTB
hsa04931__35	6.83294078171296e-07	UP	4.96652049386093	1.274984680123e-06	Insulin resistance: C00369
hsa05120__18	6.96596998994755e-07	DOWN	-4.96277782581733	1.29851762014995e-06	Epithelial cell signaling in Helicobacter pylori infection: CCL5
hsa04913__64	7.03341696290685e-07	UP	4.96090649179553	1.30979092896947e-06	Ovarian steroidogenesis: PLA2G4B
hsa04922__24	7.41555801950542e-07	UP	4.95061415467562	1.37958747709413e-06	Glucagon signaling pathway: PFKL
hsa05150__1 2 3	7.55971174074561e-07	DOWN	-4.94687148663201	1.40501467466479e-06	Staphylococcus aureus infection: CFD C3 CFB
hsa04360__89	7.63268787629311e-07	UP	4.94500015261021	1.41717594066747e-06	Axon guidance: CAMK2A
hsa05200__197	8.44107100354509e-07	DOWN	-4.9253511453813	1.5657228445865e-06	Pathways in cancer: CCND1**
hsa04014__97	8.48155373993381e-07	DOWN	-4.9244154783704	1.57168042182797e-06	Ras signaling pathway: PAK4
hsa04520__69	8.56308086427331e-07	DOWN	-4.9225441443486	1.58522452649946e-06	Adherens junction: IQGAP1**
hsa04520__17	8.64536239142438e-07	DOWN	-4.9206728103268	1.59888148951638e-06	Adherens junction: SNAI1
hsa04742__27	8.77021383720171e-07	DOWN	-4.91786580929409	1.62037677483796e-06	Taste transduction: CALHM1
hsa04933__43	8.89680057264698e-07	DOWN	-4.91505880826139	1.64215012534417e-06	AGE-RAGE signaling pathway in diabetic complications: CASP3
hsa04350__44 45	8.98216717838517e-07	UP	4.91318747423959	1.65627989481705e-06	TGF-beta signaling pathway: TGFBR2 TGFBR1
hsa04310__57	9.97480019254425e-07	UP	4.89260279999977	1.83751466292065e-06	Wnt signaling pathway: SIAH1
hsa05134__71	1.05599055492818e-06	DOWN	-4.88137479586897	1.94339495857987e-06	Legionellosis: CXCL8
hsa05168__92 93	1.06101282164531e-06	DOWN	-4.88043912885806	1.95072709576472e-06	Herpes simplex infection: IRF9 STAT1
hsa03320__41	1.10725969168744e-06	UP	4.87201812575996	2.03376437994203e-06	PPAR signaling pathway: ANGPTL4
hsa04115__39	1.13916212381078e-06	UP	4.86640412369455	2.09031799867232e-06	p53 signaling pathway: BAX
hsa05014__32 34	1.20564089652723e-06	DOWN	-4.85517611956375	2.21014560446309e-06	Amyotrophic lateral sclerosis (ALS): NEFM PRPH
hsa04670__55	1.25793325972987e-06	DOWN	-4.84675511646564	2.30375886455402e-06	Leukocyte transendothelial migration: RAC2
hsa05142__53	1.36913933927845e-06	DOWN	-4.82991311026943	2.5049784016594e-06	Chagas disease (American trypanosomiasis): AKT3
hsa04932__95	1.44846590870954e-06	DOWN	-4.81868510613862	2.64753642263154e-06	Non-alcoholic fatty liver disease (NAFLD): IL1A
hsa04390__52	1.50378588306102e-06	DOWN	-4.81119977005141	2.7459802471056e-06	Hippo signaling pathway: ITGB2
hsa04210__58	1.70588577636916e-06	UP	4.78593676075709	3.11199939203656e-06	Apoptosis: BID*
hsa04970__45	1.72988173861465e-06	DOWN	-4.78312975972439	3.15271366329479e-06	Salivary secretion: KCNMA1
hsa04115__1	1.87216192225895e-06	UP	4.76722342053908	3.40871342240753e-06	p53 signaling pathway: SIAH1
hsa04062__43	1.95196757803615e-06	DOWN	-4.75880241744097	3.55057800496605e-06	Chemokine signaling pathway: STAT1
hsa05200__198	2.09229014882505e-06	DOWN	-4.74476741227746	3.80214041551477e-06	Pathways in cancer: BCL2L1*
hsa05031__98	2.23196219347945e-06	DOWN	-4.73166807412485	4.05203571164047e-06	Amphetamine addiction: FOS
hsa04660__30	2.26303565990352e-06	DOWN	-4.72886107309215	4.10448263026903e-06	T cell receptor signaling pathway: CD40LG
hsa04360__117	2.31574999360236e-06	DOWN	-4.72418273803765	4.19604073093427e-06	Axon guidance: CFL1*
hsa05215__24	2.527022685725e-06	DOWN	-4.70640506483053	4.57444665363899e-06	Prostate cancer: CDKN1A
hsa04024__77	2.58562436690724e-06	UP	4.70172672977603	4.67602327759259e-06	cAMP signaling pathway: RHOA*
hsa04213__55	2.64552921327366e-06	DOWN	-4.69704839472153	4.77975903052039e-06	Longevity regulating pathway - multiple species: CRYAB
hsa04922__36	2.71917416177049e-06	UP	4.69143439265612	4.90809630160111e-06	Glucagon signaling pathway: GYS1
hsa04930__3	2.79478431524482e-06	DOWN	-4.68582039059072	5.03973102528312e-06	Type II diabetes mellitus: SLC2A4
hsa05161__32	2.80758056204848e-06	DOWN	-4.68488472357982	5.05795194255905e-06	Hepatitis B: STAT3
hsa05164__19	2.91199399653149e-06	DOWN	-4.67739938749261	5.24103134050064e-06	Influenza A: NFKB1
hsa04910__57	3.32261559348213e-06	UP	4.65026504417649	5.97434899536165e-06	Insulin signaling pathway: GCK
hsa04921__53	3.38343582510881e-06	DOWN	-4.64652237613289	6.07789284453103e-06	Oxytocin signaling pathway: RGS2
hsa04662__6	3.54019285995224e-06	UP	4.63716570602388	6.35341201895917e-06	B cell receptor signaling pathway: NFKB1
hsa04370__14	3.57236909503856e-06	DOWN	-4.63529437200208	6.4050396274594e-06	VEGF signaling pathway: PTGS2
hsa04650__40	3.60482561821463e-06	DOWN	-4.63342303798028	6.45707086427578e-06	Natural killer cell mediated cytotoxicity: TNFRSF10D
hsa04010__15	3.63756475642879e-06	DOWN	-4.63155170395848	6.50331510687888e-06	MAPK signaling pathway: NFKB1
hsa04360__3	3.63756475642879e-06	DOWN	-4.63155170395848	6.50331510687888e-06	Axon guidance: GNAI1
hsa05162__58	3.72066447861202e-06	DOWN	-4.62687336890397	6.64555946322433e-06	Measles: STAT3
hsa04066__49	3.77139464104843e-06	DOWN	-4.62406636787127	6.72977258359924e-06	HIF-1 signaling pathway: EPO
hsa04151__110	3.80558240298667e-06	UP	4.62219503384947	6.78433523264891e-06	PI3K-Akt signaling pathway: BCL2**
hsa04210__119	3.96313793348874e-06	DOWN	-4.61377403075136	7.05851770334156e-06	Apoptosis: BCL2*
hsa04370__39	4.39469177138381e-06	DOWN	-4.59225368950065	7.8123234043805e-06	VEGF signaling pathway: RAC1
hsa05162__81	4.39469177138381e-06	DOWN	-4.59225368950065	7.8123234043805e-06	Measles: TNFRSF10D
hsa05010__37	4.43427561173198e-06	DOWN	-4.59038235547885	7.87523995694176e-06	Alzheimer's disease: MAPT
hsa05200__223	4.55508713417317e-06	DOWN	-4.58476835341344	8.07453653312394e-06	Pathways in cancer: CCND1****
hsa05221__17	4.55508713417317e-06	DOWN	-4.58476835341344	8.07453653312394e-06	Acute myeloid leukemia: CCND1
hsa05161__92	4.74223422644404e-06	DOWN	-4.57634735031534	8.3983582577647e-06	Hepatitis B: NFKBIA
hsa05222__40	4.8710667229133e-06	UP	4.57073334824993	8.61839394760273e-06	Small cell lung cancer: TRAF1
hsa04931__140	5.44486137041082e-06	UP	4.54734167297741	9.62454799153521e-06	Insulin resistance: G00369
hsa04015__82	5.66684665095164e-06	DOWN	-4.53892066987931	1.00075233619719e-05	Rap1 signaling pathway: ITGA2B
hsa04360__6	5.84546456258548e-06	UP	4.532371000803	1.03132656461015e-05	Axon guidance: MAPK1
hsa04210__56	5.9236535385647e-06	UP	4.5295639997703	1.04414118189147e-05	Apoptosis: BAX
hsa05200__226	6.64452362116e-06	DOWN	-4.50523665748688	1.1701087051696e-05	Pathways in cancer: CDKN1A*
hsa04921__55	7.00485865578206e-06	DOWN	-4.49400865335608	1.23240912118113e-05	Oxytocin signaling pathway: PTGS2*
hsa04310__22	7.38383054968955e-06	DOWN	-4.48278064922527	1.29786881224197e-05	Wnt signaling pathway: ROCK2
hsa05150__35	7.64723123590511e-06	DOWN	-4.47529531313806	1.34291098058558e-05	Staphylococcus aureus infection: FCAR
hsa04742__4	7.74839719511879e-06	UP	4.47248831210536	1.35940600650123e-05	Taste transduction: TRPM5
hsa04810__32	7.98928652430231e-06	DOWN	-4.46593864302905	1.40036094954888e-05	Regulation of actin cytoskeleton: PXN
hsa04310__16	8.52980335312271e-06	DOWN	-4.45190363786554	1.4937092731144e-05	Wnt signaling pathway: CAMK2A
hsa05132__8	8.87070608562326e-06	DOWN	-4.44348263476744	1.55196058984042e-05	Salmonella infection: TJP1
hsa05222__35	8.98720553487617e-06	DOWN	-4.44067563373473	1.5708799255844e-05	Small cell lung cancer: NOS2
hsa04310__34	9.264749696119e-06	UP	4.43412596465843	1.61638483556245e-05	Wnt signaling pathway: FOSL1
hsa04923__31	9.264749696119e-06	DOWN	-4.43412596465843	1.61638483556245e-05	Regulation of lipolysis in adipocytes: PRKACA*
hsa04620__77	9.63364025943638e-06	UP	4.42570496156032	1.67918460551771e-05	Toll-like receptor signaling pathway: CXCL9
hsa05152__68	1.00599671017961e-05	DOWN	-4.41634829145132	1.75187008195319e-05	Tuberculosis: CD74
hsa05210__53	1.07334003161443e-05	DOWN	-4.40231328628781	1.86741288833659e-05	Colorectal cancer: CCND1*
hsa04520__10	1.10622019997018e-05	UP	4.3957636172115	1.92283788690468e-05	Adherens junction: NLK
hsa04620__29	1.11578976663261e-05	DOWN	-4.3938922831897	1.9376792712594e-05	Toll-like receptor signaling pathway: CXCL8
hsa05200__191	1.16985120823244e-05	DOWN	-4.38359994606979	2.02968644530818e-05	Pathways in cancer: CCND1*
hsa05205__451	1.21072939203806e-05	DOWN	-4.37611460998259	2.09867207346818e-05	Proteoglycans in cancer: KDR**
hsa04010__87	1.21593399677054e-05	DOWN	-4.37517894297169	2.10575113357774e-05	MAPK signaling pathway: STK3
hsa05133__94	1.26374609783573e-05	DOWN	-4.36675793987358	2.18653675675262e-05	Pertussis: IL12A
hsa04510__44	1.32462124947898e-05	DOWN	-4.35646560275367	2.28975467136247e-05	Focal adhesion: BCL2
hsa05205__319	1.37649843346296e-05	DOWN	-4.34804459965557	2.37724315852657e-05	Proteoglycans in cancer: KDR
hsa04917__34	1.38828772099838e-05	DOWN	-4.34617326563376	2.39540186203485e-05	Prolactin signaling pathway: ELF5
hsa04012__31	1.40615153332536e-05	UP	4.34336626460106	2.4239988358884e-05	ErbB signaling pathway: BAD
hsa04390__76	1.41818230834793e-05	DOWN	-4.34149493057926	2.44249730282838e-05	Hippo signaling pathway: MYC
hsa05205__113	1.42423444744582e-05	UP	4.34055926356836	2.45067447504642e-05	Proteoglycans in cancer: TP53
hsa04910__24	1.51159386420508e-05	UP	4.32745992541575	2.59861378850992e-05	Insulin signaling pathway: ACACA
hsa04024__92	1.53096721131353e-05	UP	4.32465292438305	2.62951315361803e-05	cAMP signaling pathway: GRIN3A
hsa04810__82 83	1.55716683543046e-05	UP	4.32091025633945	2.67206984819529e-05	Regulation of actin cytoskeleton: ACTB ARPC5
hsa04064__129	1.65927328704289e-05	DOWN	-4.30687525117593	2.8446847685708e-05	NF-kappa B signaling pathway: PTGS2
hsa04115__55	1.70907776674941e-05	UP	4.30032558209963	2.92739938352063e-05	p53 signaling pathway: SHISA5
hsa04540__21	1.73085580525096e-05	DOWN	-4.29751858106693	2.96200187437756e-05	Gap junction: C03758
hsa05231__21	1.82064116693493e-05	DOWN	-4.28629057693612	3.11281597149294e-05	Choline metabolism in cancer: PCYT1A
hsa04115__17	1.85934646337245e-05	UP	4.28161224188162	3.17610182243348e-05	p53 signaling pathway: TP73
hsa04620__19	1.86718101111609e-05	UP	4.28067657487071	3.1865877564824e-05	Toll-like receptor signaling pathway: CXCL10
hsa04550__9	2.02214886030138e-05	UP	4.2628989016636	3.44792895508738e-05	Signaling pathways regulating pluripotency of stem cells: HNF1A
hsa04726__38	2.06492158127158e-05	DOWN	-4.2582205666091	3.51766786147716e-05	Serotonergic synapse: PLA2G4B
hsa04360__96	2.08227071195604e-05	UP	4.2563492325873	3.54400966283099e-05	Axon guidance: GSK3B
hsa04024__24	2.29202441642387e-05	DOWN	-4.23482889133658	3.89747862304113e-05	cAMP signaling pathway: PLN
hsa04730__7	2.36958454595642e-05	DOWN	-4.22734355524937	4.02572275031836e-05	Long-term depression: GNA13
hsa04932__55	2.38936122576797e-05	UP	4.22547222122757	4.05565469125386e-05	Non-alcoholic fatty liver disease (NAFLD): CASP3
hsa05110__14	2.4496378679941e-05	DOWN	-4.21985821916217	4.14672932789271e-05	Vibrio cholerae infection: C00238*
hsa05110__15	2.4496378679941e-05	DOWN	-4.21985821916217	4.14672932789271e-05	Vibrio cholerae infection: C01330
hsa05110__16	2.4496378679941e-05	DOWN	-4.21985821916217	4.14672932789271e-05	Vibrio cholerae infection: C00698
hsa04066__53	2.54277210693676e-05	UP	4.21143721606406	4.29664459436526e-05	HIF-1 signaling pathway: EGF*
hsa05160__8	2.54277210693676e-05	DOWN	-4.21143721606406	4.29664459436526e-05	Hepatitis C: NFKB1
hsa04925__34	2.65020240907746e-05	DOWN	-4.20208054595506	4.47415123688817e-05	Aldosterone synthesis and secretion: STAR
hsa05161__10	2.77335711646277e-05	UP	4.19178820883515	4.67786177902473e-05	Hepatitis B: CASP3
hsa04066__30	2.79632567094062e-05	UP	4.18991687481335	4.71237303649993e-05	HIF-1 signaling pathway: PDK1
hsa03320__47	2.83111681001082e-05	UP	4.18710987378064	4.76672803405944e-05	PPAR signaling pathway: PLTP
hsa05168__27	2.93798059873247e-05	UP	4.17868887068254	4.94222519697253e-05	Herpes simplex infection: IRF3
hsa04973__36	2.96224308876819e-05	DOWN	-4.17681753666074	4.978582078529e-05	Carbohydrate digestion and absorption: SLC2A2
hsa04064__95	3.3090038572121e-05	DOWN	-4.15155452736642	5.55640594075204e-05	NF-kappa B signaling pathway: BCL2L1**
hsa04919__31	3.36354461455389e-05	DOWN	-4.14781185932281	5.64294672388104e-05	Thyroid hormone signaling pathway: ATP2A2
hsa04742__67	3.47519826500212e-05	UP	4.14032652323561	5.82506471002585e-05	Taste transduction: PRKACA
hsa05210__22	4.00639860412018e-05	DOWN	-4.10757817785408	6.70946789406579e-05	Colorectal cancer: MYC
hsa05166__5	4.03897059499196e-05	UP	4.10570684383228	6.75799265181647e-05	HTLV-I infection: SLC2A1
hsa05205__103	4.08830013214816e-05	DOWN	-4.10289984279958	6.83444479386689e-05	Proteoglycans in cancer: CCND1
hsa04015__67	4.10486996951572e-05	DOWN	-4.10196417578868	6.85604504241782e-05	Rap1 signaling pathway: AKT3
hsa04210__71	4.17178873789283e-05	DOWN	-4.09822150774508	6.96162614431672e-05	Apoptosis: GADD45G
hsa04024__43	4.27411072087645e-05	DOWN	-4.09260750567967	7.12604617970439e-05	cAMP signaling pathway: MAPK8
hsa05221__21	4.43206838298058e-05	DOWN	-4.08418650258157	7.38285149966358e-05	Acute myeloid leukemia: PIM1
hsa05160__12 13 14	4.68883151372941e-05	DOWN	-4.07108716442896	7.80364429964354e-05	Hepatitis C: IKBKG CHUK IKBKB
hsa05200__129 130	4.93983102666693e-05	UP	4.05892349328725	8.20684571097008e-05	Pathways in cancer: CTBP1 HDAC1
hsa05220__12 13	4.93983102666693e-05	UP	4.05892349328725	8.20684571097008e-05	Chronic myeloid leukemia: HDAC1 CTBP1
hsa05216__15	5.08020786107956e-05	DOWN	-4.05237382421094	8.43260651145626e-05	Thyroid cancer: CCND1
hsa04913__45	5.22435996645321e-05	UP	4.04582415513464	8.66422981197316e-05	Ovarian steroidogenesis: ACOT2
hsa04730__8	5.35099581086488e-05	DOWN	-4.04021015306923	8.86642074833783e-05	Long-term depression: GNA13*
hsa04621__43	5.39385021051318e-05	DOWN	-4.03833881904743	8.92955466568658e-05	NOD-like receptor signaling pathway: MAPK1
hsa04115__56	5.59075094885211e-05	DOWN	-4.02991781594933	9.24737766980028e-05	p53 signaling pathway: SESN3
hsa04152__27	5.98139370219758e-05	DOWN	-4.01401147676401	9.88481861603277e-05	AMPK signaling pathway: ADIPOR1
hsa04340__20 22	6.29741373739058e-05	DOWN	-4.00184780562231	0.000103979265488198	Hedgehog signaling pathway: GLI1 SUFU*
hsa04650__15	6.39778811076202e-05	DOWN	-3.9981051375787	0.000105543844250411	Natural killer cell mediated cytotoxicity: TNF
hsa04810__26 80	6.4740606818462e-05	DOWN	-3.995298136546	0.0001067084212385	Regulation of actin cytoskeleton: PFN3 ACTB
hsa04210__114	6.52538633400121e-05	DOWN	-3.9934268025242	0.000107460130776409	Apoptosis: HRK
hsa04931__47	6.76115473054202e-05	UP	3.98500579942609	0.000111245269165398	Insulin resistance: AKT2*
hsa05162__44	6.84151947459322e-05	DOWN	-3.98219879839339	0.000112469073427477	Measles: PRKCQ
hsa04022__58	6.92278747082589e-05	DOWN	-3.97939179736069	0.000113705573930785	cGMP-PKG signaling pathway: MYH7
hsa05014__5	7.14399060086395e-05	UP	3.97190646127348	0.000117236317371383	Amyotrophic lateral sclerosis (ALS): TOMM40
hsa04724__68	7.25708345659634e-05	DOWN	-3.96816379322988	0.000118988305540528	Glutamatergic synapse: MAPK1
hsa04520__9 57	7.31426288609845e-05	DOWN	-3.96629245920808	0.000119821272563025	Adherens junction: LEF1 CTNNB1
hsa04623__17	7.57688423301888e-05	UP	3.95787145610997	0.000124015378692008	Cytosolic DNA-sensing pathway: NFKB1
hsa04360__18	7.63644329543313e-05	DOWN	-3.95600012208817	0.000124881435614611	Axon guidance: PTK2
hsa04340__13	7.66638857198983e-05	DOWN	-3.95506445507727	0.000125262122841469	Hedgehog signaling pathway: GLI1*
hsa04917__48	7.84840492782569e-05	DOWN	-3.94945045301187	0.000128124699038962	Prolactin signaling pathway: CCND2
hsa04520__4	8.06592034158968e-05	DOWN	-3.94290078393556	0.000131561322238255	Adherens junction: CTNND1
hsa04015__95	8.41927921171279e-05	UP	3.93260844681565	0.000137205773103281	Rap1 signaling pathway: THBS1
hsa04666__42	8.58468799281857e-05	DOWN	-3.92793011176115	0.000139780145047713	Fc gamma R-mediated phagocytosis: MYO10
hsa04390__59	8.65170739476736e-05	DOWN	-3.92605877773935	0.000140749421599722	Hippo signaling pathway: SERPINE1
hsa04950__13	8.719220940046e-05	DOWN	-3.92418744371755	0.000141725053169087	Maturity onset diabetes of the young: INS
hsa04390__90	9.27753165509214e-05	UP	3.90921677154314	0.000150669680033865	Hippo signaling pathway: BBC3
hsa04540__11	9.38590490403118e-05	UP	3.90640977051043	0.000152166655001506	Gap junction: C00780
hsa05132__41	9.38590490403118e-05	UP	3.90640977051043	0.000152166655001506	Salmonella infection: ACTB*
hsa04152__63	9.86948697004662e-05	DOWN	-3.89424609936872	0.00015986867255791	AMPK signaling pathway: PPARG
hsa03320__43	0.000102573785900979	DOWN	-3.88488942925972	0.000166008737043875	PPAR signaling pathway: ILK
hsa04810__29	0.000103366641680194	DOWN	-3.88301809523792	0.000167147951563755	Regulation of actin cytoskeleton: ACTN4
hsa04740__13	0.000108246573610413	UP	3.87179009110711	0.000174888488232129	Olfactory transduction: CNGA3
hsa04064__93	0.000115533035507131	UP	3.8558837519218	0.000186500492884793	NF-kappa B signaling pathway: PLAU
hsa05205__233 234	0.000117762627527599	DOWN	-3.85120541686729	0.000189936461050951	Proteoglycans in cancer: ITGA2 C00925
hsa04115__49	0.000120032749644495	UP	3.84652708181279	0.000193431849555752	p53 signaling pathway: MDM2*
hsa04350__12	0.000125173081462687	UP	3.83623474469288	0.000201542605028611	TGF-beta signaling pathway: ACVR2A
hsa03320__46	0.000134034554555628	UP	3.81939273849667	0.000215625794529131	PPAR signaling pathway: APOA2
hsa05169__118	0.000137637709941965	UP	3.81284306942036	0.000221232897331868	Epstein-Barr virus infection: MDM2
hsa04010__57	0.000139209684088125	DOWN	-3.81003606838766	0.000223568372992809	MAPK signaling pathway: NLK
hsa04152__44	0.000143484697339521	DOWN	-3.80255073230046	0.000230237187276652	AMPK signaling pathway: SLC2A4
hsa05016__55	0.000144027684416488	UP	3.80161506528956	0.000230911279026093	Huntington's disease: TGM2
hsa04010__118	0.00014677176783345	UP	3.79693673023505	0.000235110103801408	MAPK signaling pathway: JUN
hsa04024__112	0.000149002400278455	DOWN	-3.79319406219145	0.000238277029892099	cAMP signaling pathway: GLI1
hsa05152__97	0.000149002400278455	DOWN	-3.79319406219145	0.000238277029892099	Tuberculosis: IL18
hsa05200__196	0.000149565024642989	UP	3.79225839518055	0.000238973368455932	Pathways in cancer: TRAF1
hsa04662__35	0.000150696278944245	UP	3.79038706115875	0.00024057630257964	B cell receptor signaling pathway: CD79B
hsa04390__79	0.000154138564941285	DOWN	-3.78477305909334	0.00024586278737239	Hippo signaling pathway: SNAI2
hsa05142__36	0.000154719425870027	DOWN	-3.78383739208244	0.000246579984062578	Chagas disease (American trypanosomiasis): SMAD2
hsa04151__103	0.000155887334149064	DOWN	-3.78196605806064	0.000248020576516588	PI3K-Akt signaling pathway: BCL2*
hsa04920__10	0.000155887334149064	DOWN	-3.78196605806064	0.000248020576516588	Adipocytokine signaling pathway: PCK1
hsa04921__33	0.000166155003644547	DOWN	-3.76605971887533	0.000264133038788581	Oxytocin signaling pathway: C00942
hsa05205__422	0.000168031572342092	DOWN	-3.76325271784263	0.000266890384134227	Proteoglycans in cancer: CD63
hsa04668__48	0.000174432501397773	UP	3.75389604773362	0.000276823201120284	TNF signaling pathway: CASP3
hsa05223__14	0.00017639700611038	DOWN	-3.75108904670092	0.000279704619815531	Non-small cell lung cancer: CCND1
hsa05161__78	0.000185842925536543	DOWN	-3.73798970854831	0.000294434112211775	Hepatitis B: TNF
hsa04713__14	0.000187230530384401	DOWN	-3.73611837452651	0.000296382617179688	Circadian entrainment: PRKCA
hsa04012__25	0.000191452004190733	UP	3.7305043724611	0.000302810030197295	ErbB signaling pathway: CDKN1B
hsa05200__199	0.000192878927665081	DOWN	-3.7286330384393	0.000304554205951838	Pathways in cancer: BCL2L1**
hsa05220__3	0.000192878927665081	DOWN	-3.7286330384393	0.000304554205951838	Chronic myeloid leukemia: BCL2L1
hsa04950__30	0.00019359613158397	UP	3.7276973714284	0.000305430001046414	Maturity onset diabetes of the young: PAX6*
hsa05212__19	0.000196490084350095	UP	3.7239547033848	0.000309735627931064	Pancreatic cancer: MAPK8
hsa05205__434	0.000200164697345555	UP	3.71927636833029	0.000315263592885413	Proteoglycans in cancer: CASP3
hsa04710__5	0.000207708440494234	UP	3.70991969822129	0.000326871155518146	Circadian rhythm: RORA
hsa04340__50	0.000215518607614188	DOWN	-3.70056302811228	0.000338878212307162	Hedgehog signaling pathway: BCL2
hsa05166__34 35 36	0.000216314287363843	DOWN	-3.69962736110138	0.000339844938090854	HTLV-I infection: MYC TRRAP KAT5
hsa04151__109	0.000220336200573083	UP	3.69494902604687	0.000345874453531181	PI3K-Akt signaling pathway: RXRA
hsa04012__43	0.000221148896230918	UP	3.69401335903597	0.000346860414038309	ErbB signaling pathway: PTK2
hsa05160__37	0.00023201816651394	DOWN	-3.68091402088336	0.000363604783052288	Hepatitis C: STAT3
hsa05200__183	0.000233682049640705	DOWN	-3.67997835387246	0.000365907142729071	Pathways in cancer: BMP2
hsa05160__66	0.000241518725311517	DOWN	-3.67155735077436	0.000377863184729675	Hepatitis C: GSK3B
hsa04360__51	0.000243293374318372	UP	3.66968601675256	0.00038032300361416	Axon guidance: FYN
hsa03320__21	0.000253274606564866	DOWN	-3.65939367963265	0.000395596829372721	PPAR signaling pathway: ACAA1
hsa04115__29	0.000254200784636955	DOWN	-3.65845801262175	0.000396713683000697	p53 signaling pathway: IGF1
hsa05152__76	0.000262680495941058	DOWN	-3.65003700952364	0.000409607179977799	Tuberculosis: TNF*
hsa05212__8	0.000267505319022255	DOWN	-3.64535867446914	0.0004167848212627	Pancreatic cancer: NFKB1
hsa04662__29	0.000268480199134175	UP	3.64442300745824	0.000417957161701007	B cell receptor signaling pathway: RAC1
hsa04210__52	0.000269458408800401	UP	3.64348734044734	0.000419132740178769	Apoptosis: PARP2
hsa04912__43	0.000270439958533194	DOWN	-3.64255167343644	0.000420311564999067	GnRH signaling pathway: PTK2B
hsa05145__11	0.000285571253405692	UP	3.62851666827292	0.000443461475329996	Toxoplasmosis: MAPK14
hsa05215__13	0.000298243592169726	DOWN	-3.61728866414212	0.000462757811467312	Prostate cancer: BCL2
hsa04014__37	0.000301492969278597	DOWN	-3.61448166310941	0.000467413605011951	Ras signaling pathway: FASLG
hsa04621__21 31 41	0.000305877063280297	DOWN	-3.61073899506581	0.000473819457463872	NOD-like receptor signaling pathway: NLRP3 CARD8 CASP1
hsa04724__13	0.000310319825312458	UP	3.60699632702221	0.000480305561583286	Glutamatergic synapse: GRM5
hsa04722__70	0.000312565262841185	UP	3.60512499300041	0.000483382822122294	Neurotrophin signaling pathway: ZNF274
hsa04211__38	0.000329889577278482	UP	3.5910899878369	0.000509755358311076	Longevity regulating pathway - mammal: BAX
hsa04910__12	0.000348109297695261	UP	3.57705498267339	0.000537467025776004	Insulin signaling pathway: FASN
hsa04115__18	0.000371214871735188	UP	3.56021297647717	0.000572670561568488	p53 signaling pathway: CCNG1
hsa04360__111	0.000376540530673893	UP	3.55647030843357	0.000580409891005943	Axon guidance: RHOA***
hsa04727__26	0.000388785486569791	UP	3.54804930533546	0.000597324553773212	GABAergic synapse: KCNJ6
hsa05032__81	0.000388785486569791	UP	3.54804930533546	0.000597324553773212	Morphine addiction: KCNJ6
hsa05032__91	0.000388785486569791	UP	3.54804930533546	0.000597324553773212	Morphine addiction: KCNJ6**
hsa05032__85	0.000388785486569791	UP	3.54804930533546	0.000597324553773212	Morphine addiction: KCNJ6*
hsa05205__189	0.000420301846951226	DOWN	-3.52746463109565	0.000645218276488034	Proteoglycans in cancer: IL12B
hsa05161__66 67	0.00043693999245861	DOWN	-3.51717229397574	0.000670212445575288	Hepatitis B: NFKB1 NFKBIA
hsa04210__83	0.000438482653245286	DOWN	-3.51623662696484	0.000672030102322913	Apoptosis: TP53*
hsa04390__74	0.0004720767276778	DOWN	-3.49658761973593	0.000722927604976843	Hippo signaling pathway: AXIN1
hsa04064__50	0.00049061735790776	DOWN	-3.48629528261602	0.000750708481684594	NF-kappa B signaling pathway: NFKBIA*
hsa04911__54	0.000504525558061512	DOWN	-3.47880994652881	0.000771361695360115	Insulin secretion: RAB3A
hsa04064__51	0.000506289699183712	DOWN	-3.47787427951791	0.000773429548590402	NF-kappa B signaling pathway: TNFAIP3
hsa04350__34	0.00051161668727028	DOWN	-3.47506727848521	0.000780932376426366	TGF-beta signaling pathway: ROCK1
hsa04014__100	0.000516995884715712	DOWN	-3.47226027745251	0.000788502652094824	Ras signaling pathway: REL
hsa04722__37	0.000533451441021676	UP	3.4638392743544	0.000812940192765392	Neurotrophin signaling pathway: NFKB1
hsa05131__38	0.000560021780492189	UP	3.45073993620179	0.000852739810003908	Shigellosis: CXCL8
hsa04726__45	0.000563913682576734	DOWN	-3.44886860217999	0.000857970696001363	Serotonergic synapse: TRPC1
hsa05150__48	0.000573764412395504	DOWN	-3.44419026712549	0.000872251885834265	Staphylococcus aureus infection: C3AR1
hsa04520__43	0.000604276611688543	DOWN	-3.43015526196198	0.000917894707649775	Adherens junction: ACTB
hsa04610__58	0.000608457495324822	UP	3.42828392794017	0.000923498896377496	Complement and coagulation cascades: F2RL2
hsa05150__66	0.000612664968700291	DOWN	-3.42641259391837	0.000929134363347737	Staphylococcus aureus infection: IL10
hsa05200__190	0.000616899503198586	DOWN	-3.42454125989657	0.000934801747185599	Pathways in cancer: MYC*
hsa05215__14	0.000621161257943971	DOWN	-3.42266992587477	0.000940501211665367	Prostate cancer: CCND1
hsa04621__21 30	0.000629767068834807	UP	3.41892725783117	0.000952763544557651	NOD-like receptor signaling pathway: NLRP3 PYCARD
hsa04668__116	0.000636294075908685	UP	3.41612025679847	0.000961863691578776	TNF signaling pathway: PGAM5
hsa04921__34 35	0.000640680313312463	DOWN	-3.41424892277666	0.000967715682246076	Oxytocin signaling pathway: MYL9 ACTB
hsa05200__224	0.000651769250082527	DOWN	-3.40957058772216	0.000982884767981596	Pathways in cancer: MYC***
hsa05221__12	0.000651769250082527	DOWN	-3.40957058772216	0.000982884767981596	Acute myeloid leukemia: MYC
hsa04742__23 45	0.000663030362602196	DOWN	-3.40489225266766	0.000999064997056558	Taste transduction: PKD1L3 PKD2L1
hsa05161__30	0.000693184399086595	DOWN	-3.39272858152595	0.00104366465215041	Hepatitis B: MYC
hsa04510__42	0.00071723678760956	UP	3.38337191141694	0.00107901354997467	Focal adhesion: BIRC2
hsa05162__25 70	0.000762495482739091	DOWN	-3.36652990522073	0.0011461832096534	Measles: IFNAR1 GNB2L1
hsa04020__16	0.000796816142486778	UP	3.35436623407902	0.00119681657212842	Calcium signaling pathway: C06124
hsa05014__51	0.000799514509617086	DOWN	-3.35343056706812	0.00119991035428954	Amyotrophic lateral sclerosis (ALS): DERL1
hsa04213__2	0.000815885020651814	UP	3.34781656500271	0.00122350195834378	Longevity regulating pathway - multiple species: RPS6KB1
hsa04024__2	0.000832565872322271	DOWN	-3.34220256293731	0.00124752095222771	cAMP signaling pathway: CACNA1C
hsa04742__37	0.000838189476675525	UP	3.34033122891551	0.00125395736437217	Taste transduction: P2RY4
hsa04670__54	0.000838196088159365	DOWN	-3.34033122891551	0.00125395736437217	Leukocyte transendothelial migration: RAC1*
hsa04550__47	0.00084102442065497	UP	3.33939556190461	0.00125618830398306	Signaling pathways regulating pluripotency of stem cells: CTNNB1*
hsa05231__17	0.00084102442065497	UP	3.33939556190461	0.00125618830398306	Choline metabolism in cancer: SLC44A3
hsa05211__40	0.000872725745485663	UP	3.3291032247847	0.00130250331673357	Renal cell carcinoma: PAK4
hsa04742__48	0.000887498611333291	UP	3.3244248897302	0.0013234999132502	Taste transduction: GABBR1
hsa05200__222	0.00090857031676059	UP	3.31787522065389	0.00135384902870194	Pathways in cancer: CASP9*
hsa04510__47	0.000911618130925802	DOWN	-3.31693955364299	0.0013573141584862	Focal adhesion: CCND1
hsa04064__134	0.000914675417491998	DOWN	-3.31600388663209	0.00136078789348176	NF-kappa B signaling pathway: CCL21
hsa05321__138	0.000923904379475929	UP	3.31319688559939	0.00137343064005955	Inflammatory bowel disease (IBD): IFNG**
hsa04971__52 53	0.000984387103014075	DOWN	-3.29541921239227	0.0014621844794968	Gastric acid secretion: EZR ACTB
hsa04668__111	0.000997578703744639	DOWN	-3.29167654434867	0.001480608518433	TNF signaling pathway: BAG4
hsa04210__70	0.00104851841871577	DOWN	-3.27764153918516	0.0015537587608572	Apoptosis: CFLAR*
hsa05162__105	0.00104851841871577	DOWN	-3.27764153918516	0.0015537587608572	Measles: GSK3B
hsa05222__36	0.0010625031418437	DOWN	-3.27389887114156	0.00157324145273783	Small cell lung cancer: PTGS2
hsa04930__7	0.00106602618302809	DOWN	-3.27296320413066	0.00157721511646439	Type II diabetes mellitus: C00002
hsa04976__34	0.001087392366939	DOWN	-3.26734920206525	0.00160756117818913	Bile secretion: SLCO1B1
hsa04210__64	0.00117687856474456	UP	3.24489319380364	0.00173848649619105	Apoptosis: TNFRSF10D*
hsa04912__20	0.00121613469595271	DOWN	-3.23553652369463	0.0017950644883701	GnRH signaling pathway: PLA2G4B
hsa04370__28	0.00122412963448491	DOWN	-3.23366518967283	0.00180544708257233	VEGF signaling pathway: SHC2
hsa05200__217	0.00124026533505533	UP	3.22992252162923	0.00182781063887762	Pathways in cancer: E2F1*
hsa04012__56	0.00127312752593683	DOWN	-3.22243718554202	0.00187330197434244	ErbB signaling pathway: JUN
hsa04976__59	0.00127312752593683	UP	3.22243718554202	0.00187330197434244	Bile secretion: ABCB4
hsa04151__100	0.00128565672025344	DOWN	-3.21963018450932	0.00189025741577169	PI3K-Akt signaling pathway: PRKCA
hsa04670__10	0.00128985834563443	DOWN	-3.21869451749842	0.00189495217470453	Leukocyte transendothelial migration: BCAR1
hsa04115__16	0.00134127611349525	DOWN	-3.20746651336761	0.00196895141973247	p53 signaling pathway: PPM1D
hsa05031__10	0.00137659814623511	DOWN	-3.1999811772804	0.00201765048110434	Amphetamine addiction: CACNA1C
hsa05031__53	0.00137659814623511	DOWN	-3.1999811772804	0.00201765048110434	Amphetamine addiction: CACNA1C*
hsa04390__14	0.00140365050380913	DOWN	-3.194367175215	0.00205409602543407	Hippo signaling pathway: AREG
hsa04976__41	0.00140365050380913	DOWN	-3.194367175215	0.00205409602543407	Bile secretion: CYP7A1
hsa05161__227	0.00151195549541113	DOWN	-3.17284683396428	0.00221086721858173	Hepatitis B: MYD88*
hsa04710__11	0.00154144830001595	DOWN	-3.16723283189888	0.00225224055655519	Circadian rhythm: CRY1
hsa04210__85	0.00159689856368265	DOWN	-3.15694049477897	0.00233144708714817	Apoptosis: FASLG*
hsa05161__126	0.00163313503725993	DOWN	-3.15039082570267	0.00238250057066103	Hepatitis B: MYC*
hsa04728__54	0.00165417983188301	DOWN	-3.14664815765906	0.00241132963856336	Dopaminergic synapse: CAMK2A
hsa05131__12	0.0017243106986393	DOWN	-3.13448448651735	0.00251161225018857	Shigellosis: ARPC5
hsa04610__7	0.00184925131643709	DOWN	-3.11389981227754	0.00269151295397777	Complement and coagulation cascades: C00290
hsa04660__26	0.00186691874620027	UP	3.11109281124484	0.00271512408986866	T cell receptor signaling pathway: GRB2
hsa05216__11	0.0018787830349632	DOWN	-3.10922147722304	0.00273026552412672	Thyroid cancer: MYC
hsa05321__46	0.00189071654555543	DOWN	-3.10735014320123	0.0027454840719464	Inflammatory bowel disease (IBD): IFNG*
hsa04810__23	0.00192085554609871	DOWN	-3.10267180814673	0.00278709464951311	Regulation of actin cytoskeleton: GSN
hsa04340__32	0.00198246111084817	DOWN	-3.09331513803772	0.00287426267537324	Hedgehog signaling pathway: PTCH1***
hsa04919__46	0.00200760717606093	DOWN	-3.08957246999412	0.00290847639461718	Thyroid hormone signaling pathway: ATP1B4
hsa04920__6	0.00204587549684084	DOWN	-3.08395846792872	0.00296163332709087	Adipocytokine signaling pathway: PTPN11
hsa04012__3	0.00215796587242442	UP	3.0680521287434	0.0031190906725273	ErbB signaling pathway: ELK1
hsa04950__21	0.00215796587242442	UP	3.0680521287434	0.0031190906725273	Maturity onset diabetes of the young: PKLR
hsa05205__369	0.00221956133160887	UP	3.0596311256453	0.00320565391398391	Proteoglycans in cancer: HOXD10
hsa05160__77	0.00222650381573288	DOWN	-3.0586954586344	0.00321321095987871	Hepatitis C: NFKB1*
hsa04920__26	0.00226151566963172	DOWN	-3.05401712357989	0.0032612340316485	Adipocytokine signaling pathway: NPY
hsa05169__93	0.0023113800121213	UP	3.04746745450359	0.00333058515550301	Epstein-Barr virus infection: PLCG1
hsa04072__3	0.00238436283477957	DOWN	-3.03811078439458	0.00343311706249104	Phospholipase D signaling pathway: MAPK1
hsa05132__20	0.00239921018063738	DOWN	-3.03623945037278	0.00345184986938564	Salmonella infection: ACTB
hsa05031__96	0.00242915906247352	DOWN	-3.03249678232918	0.00349226463533875	Amphetamine addiction: PDYN
hsa04064__113	0.00251329130851022	DOWN	-3.02220444520927	0.00361045441031399	NF-kappa B signaling pathway: CFLAR
hsa05200__204	0.00267311989892199	DOWN	-3.00349110499126	0.00383712168836854	Pathways in cancer: TGFB1*
hsa04064__130	0.00269787972928371	DOWN	-3.00068410395855	0.00386675515737917	NF-kappa B signaling pathway: TNF*
hsa04115__34	0.00269787972928371	UP	3.00068410395855	0.00386675515737917	p53 signaling pathway: ZMAT3
hsa04931__67	0.00285961375909873	UP	2.98290643075144	0.00409543769309947	Insulin resistance: IKBKB**
hsa04912__17	0.00296628299613554	DOWN	-2.97167842662063	0.00424497010642702	GnRH signaling pathway: MAPK14
hsa05016__12	0.00298440904480317	DOWN	-2.96980709259883	0.00426765950927333	Huntington's disease: REST
hsa05164__47	0.0029935099130177	DOWN	-2.96887142558793	0.00427741834719411	Influenza A: CIITA
hsa04913__35	0.00301178764850893	DOWN	-2.96700009156613	0.00430026519114611	Ovarian steroidogenesis: HSD17B2
hsa04930__13	0.0030209646406924	DOWN	-2.96606442455523	0.00431009305987928	Type II diabetes mellitus: C00162
hsa04010__131	0.0030579282356206	UP	2.96232175651162	0.00435951984425729	MAPK signaling pathway: MYC
hsa04668__38	0.00310471262078872	UP	2.95764342145712	0.00442286202764368	TNF signaling pathway: CEBPB
hsa05200__202	0.00316171488826455	UP	2.95202941939172	0.00450065323867355	Pathways in cancer: FIGF*
hsa04014__35	0.00326870277007329	DOWN	-2.94173708227181	0.0046459096104143	Ras signaling pathway: NFKB1
hsa04723__67	0.00326870277007329	DOWN	-2.94173708227181	0.0046459096104143	Retrograde endocannabinoid signaling: PRKACA
hsa05166__33	0.00333423663303837	UP	2.73589033987365	0.00473547289000688	HTLV-I infection: HLA-A
hsa04922__37	0.00337897893848398	UP	2.9314447451519	0.00479539382583942	Glucagon signaling pathway: PYGB
hsa04210__86	0.00347171286855332	DOWN	-2.9230237420538	0.00492328187170693	Apoptosis: BCL2L11
hsa04210__73	0.00353481602634174	UP	2.91740973998839	0.00500898892420522	Apoptosis: TRAF1
hsa04666__23	0.00354543410484528	DOWN	-2.91647407297749	0.0050202491959339	Fc gamma R-mediated phagocytosis: RPS6KB1
hsa03320__62	0.00366416238360477	UP	2.90618173585758	0.00518445867379018	PPAR signaling pathway: UBC
hsa04151__27	0.00367513392505103	DOWN	-2.90524606884668	0.00519216289110593	PI3K-Akt signaling pathway: FASLG
hsa04380__48	0.00367513392505103	UP	2.90524606884668	0.00519216289110593	Osteoclast differentiation: NFATC1
hsa05205__144	0.00374158852424836	UP	2.89963206678128	0.00528207726300726	Proteoglycans in cancer: NUDT16L1
hsa04390__18	0.0039241747166242	UP	2.88466139460687	0.00553567889830095	Hippo signaling pathway: MOB1A
hsa04668__138	0.004078443898179	DOWN	-2.87249772346516	0.00574898430958615	TNF signaling pathway: NFKB1*
hsa04662__24	0.00410266018756519	DOWN	-2.87062638944336	0.0057787844770877	B cell receptor signaling pathway: FOS
hsa05120__52	0.00421325631443697	UP	2.86220538634525	0.00593011881260455	Epithelial cell signaling in Helicobacter pylori infection: LYN
hsa05221__29	0.00423819755838885	UP	2.86033405232345	0.00596075839237474	Acute myeloid leukemia: RPS6KB1
hsa04210__4	0.00446876754050296	UP	2.84349204612724	0.0062803397222177	Apoptosis: DFFA
hsa04310__35	0.00453480135156606	UP	2.83881371107273	0.00636837947652663	Wnt signaling pathway: JUN
hsa05162__20	0.00458826344442756	DOWN	-2.83507104302913	0.00643864601350216	Measles: NFKB1
hsa04921__43	0.00471064603858303	UP	2.82665003993102	0.00660545067649068	Oxytocin signaling pathway: CACNG3
hsa05142__84	0.00473824029080021	DOWN	-2.82477870590922	0.00663918978852617	Chagas disease (American trypanosomiasis): NFKB1*
hsa04390__96	0.00475209221013534	DOWN	-2.82384303889832	0.00665363730465298	Hippo signaling pathway: FGF1
hsa05145__10	0.00480786715092323	UP	2.82010037085472	0.00672671807638478	Toxoplasmosis: MAPK8
hsa05161__214	0.004835976169579	UP	2.81822903683292	0.00676101132636826	Hepatitis B: CDKN1B
hsa04728__24	0.00493553254424251	UP	2.81167936775661	0.00689506739823916	Dopaminergic synapse: SLC6A3
hsa05205__183	0.00496431572643613	UP	2.80980803373481	0.00693012574292235	Proteoglycans in cancer: VEGFA*
hsa05010__49	0.00506625622752598	UP	2.80325836465851	0.00706718296326749	Alzheimer's disease: EIF2AK3
hsa04740__37	0.00509572765233053	UP	2.8013870306367	0.00710302096344886	Olfactory transduction: CNGB1*
hsa04024__34	0.00511052139993774	DOWN	-2.8004513636258	0.00711836153482803	cAMP signaling pathway: ATP2B1
hsa04921__77	0.00527583358216552	DOWN	-2.7901590265059	0.00734317874139927	Oxytocin signaling pathway: KCNJ3
hsa05210__16	0.005291098924861	UP	2.78922335949499	0.00735897474449579	Colorectal cancer: MAPK8
hsa04064__52	0.00533713462369187	UP	2.78641635846229	0.00741751180319306	NF-kappa B signaling pathway: TRAF1
hsa04370__15	0.00535256005002142	DOWN	-2.78548069145139	0.00743345183591297	VEGF signaling pathway: PLA2G4B
hsa05142__44	0.00546167012995818	DOWN	-2.77893102237509	0.00757937826749736	Chagas disease (American trypanosomiasis): PLCB1
hsa04024__60	0.00552491635330096	DOWN	-2.77518835433148	0.00766148917184687	cAMP signaling pathway: PDE3A
hsa04330__19	0.00568593350353653	UP	2.76583168422248	0.00787895947872061	Notch signaling pathway: DTX2
hsa04912__46	0.00612457018961698	DOWN	-2.74150434193906	0.00848052128687568	GnRH signaling pathway: JUN
hsa05160__22 23	0.00623002535476123	UP	2.73589033987365	0.00862018972135224	Hepatitis C: STAT1 IRF9
hsa05212__29	0.006500850789665	UP	2.72185533471014	0.00898829921543822	Pancreatic cancer: VEGFA
hsa05162__101	0.00651927686165206	UP	2.72091966769924	0.00900714795812076	Measles: CDKN1B
hsa05110__12	0.00659345180675085	DOWN	-2.71717699965564	0.00909625252928403	Vibrio cholerae infection: C00080
hsa05120__35	0.00659345180675085	DOWN	-2.71717699965564	0.00909625252928403	Epithelial cell signaling in Helicobacter pylori infection: C00080
hsa04726__41	0.00668723726154091	UP	2.71249866460114	0.00921211056776787	Serotonergic synapse: HTR3C
hsa04742__57	0.00668723726154091	UP	2.71249866460114	0.00921211056776787	Taste transduction: HTR3C
hsa05200__195	0.00678222022500379	DOWN	-2.70782032954663	0.00933611121082939	Pathways in cancer: BIRC8
hsa04666__40	0.00682055166243405	DOWN	-2.70594899552483	0.00938200334825299	Fc gamma R-mediated phagocytosis: PLA2G6
hsa04921__65	0.00687841388225272	UP	2.70314199449213	0.00945467423902916	Oxytocin signaling pathway: TRPM2
hsa05205__220	0.00709436728246418	DOWN	-2.69284965737222	0.00974438313139634	Proteoglycans in cancer: FAS
hsa04620__66	0.00713427920888181	UP	2.69097832335042	0.00979204575127022	Toll-like receptor signaling pathway: CASP8
hsa04976__95 96	0.00729590826463841	UP	2.68349298726322	0.0100065778315734	Bile secretion: SLC51A SLC51B
hsa04660__14	0.00758680069788192	DOWN	-2.67039364911061	0.010397956609278	T cell receptor signaling pathway: NFKB1
hsa04150__31	0.0076504620033227	DOWN	-2.6675866480779	0.0104775642159208	mTOR signaling pathway: EIF4E
hsa04064__3	0.00767178859646802	DOWN	-2.666650981067	0.0104991192809639	NF-kappa B signaling pathway: BCL2
hsa04020__7	0.00777922288591371	DOWN	-2.6619726460125	0.0106383986918718	Calcium signaling pathway: ADCY1
hsa04340__49	0.00810966010673876	DOWN	-2.64793764084899	0.0110822191567725	Hedgehog signaling pathway: CCND1
hsa04024__93	0.00840614293371903	DOWN	-2.63577396970728	0.0114790280323096	cAMP signaling pathway: ORAI1
hsa04550__22	0.00849929904477313	UP	2.63203130166368	0.0115978089361864	Signaling pathways regulating pluripotency of stem cells: SMAD2
hsa04961__13	0.00852273183655681	DOWN	-2.63109563465278	0.0116213447901961	Endocrine and other factor-regulated calcium reabsorption: ATP2B1
hsa04724__52	0.00871228335801629	UP	2.62361029856557	0.0118711968308286	Glutamatergic synapse: CACNA1A
hsa04550__66	0.0087843308073731	DOWN	-2.62080329753287	0.0119606939036624	Signaling pathways regulating pluripotency of stem cells: MYC
hsa04152__58	0.00932914827044519	DOWN	-2.60021862329305	0.0126933161478396	AMPK signaling pathway: SCD
hsa04340__40	0.00943138358749774	UP	2.59647595524945	0.0128231329673721	Hedgehog signaling pathway: SUFU
hsa04110__48	0.00985038955035811	UP	2.58150528307504	0.0133831395264808	Cell cycle: RB1*
hsa04722__85	0.0100117432851417	DOWN	-2.57589128100963	0.0135925329716627	Neurotrophin signaling pathway: BAX
hsa04390__80	0.0100388632536346	DOWN	-2.57495561399873	0.0136195119520429	Hippo signaling pathway: BIRC2
hsa04380__51	0.0104817696470104	UP	2.55998494182432	0.0142101335979312	Osteoclast differentiation: FOS*
hsa04728__36	0.0108252685729206	UP	2.54875693769351	0.0146652340652616	Dopaminergic synapse: TH
hsa04670__39	0.0109419762023337	DOWN	-2.54501426964991	0.0148126608675685	Leukocyte transendothelial migration: MAPK14
hsa05161__26	0.011329024681992	UP	2.5328505985082	0.0153255848649841	Hepatitis B: MMP9
hsa04930__8	0.0117281808133441	DOWN	-2.52068692736649	0.0158541379483982	Type II diabetes mellitus: C00022
hsa05231__48	0.0117906842643474	UP	2.51881559334469	0.0159271716266778	Choline metabolism in cancer: WAS
hsa05200__200	0.0120436623553933	UP	2.51133025725749	0.016257213768523	Pathways in cancer: FIGF
hsa04912__19	0.0126305278895983	DOWN	-2.49448825106127	0.0170371585818774	GnRH signaling pathway: MAPK7
hsa04666__29	0.0128655033238839	DOWN	-2.48793858198497	0.0173416648103142	Fc gamma R-mediated phagocytosis: WAS
hsa05205__150	0.0132425649755618	DOWN	-2.47764624486506	0.0178371179850041	Proteoglycans in cancer: PRKCA
hsa04370__23	0.0135583099319292	DOWN	-2.46922524176695	0.0182362665440909	VEGF signaling pathway: PTK2
hsa04621__30 32	0.0135583099319292	UP	2.46922524176695	0.0182362665440909	NOD-like receptor signaling pathway: PYCARD CASP1
hsa05217__3	0.0137365803110999	DOWN	-2.46454690671245	0.0184628286155628	Basal cell carcinoma: GLI1
hsa04210__102	0.0137724817838267	DOWN	-2.46361123970155	0.0184978508018658	Apoptosis: PIDD1
hsa05032__38	0.0145081205301371	UP	2.44489789948354	0.0194580717174358	Morphine addiction: CACNA1A
hsa05140__43	0.0145081205301371	DOWN	-2.44489789948354	0.0194580717174358	Leishmaniasis: MAPK14
hsa04014__70	0.0146593379976561	UP	2.44115523143993	0.0196468588427931	Ras signaling pathway: RIN1*
hsa04071__65	0.0146973587727138	UP	2.44021956442903	0.019683775576571	Sphingolipid signaling pathway: BAX*
hsa04115__21	0.0150434757880402	UP	2.43179856133093	0.0201329708018003	p53 signaling pathway: DDB2
hsa04152__81	0.0152388488138236	UP	2.42712022627642	0.0203654316651312	AMPK signaling pathway: LIPE
hsa04340__26	0.0152388488138236	DOWN	-2.42712022627642	0.0203654316651312	Hedgehog signaling pathway: PTCH1**
hsa05223__23	0.0155161232518683	DOWN	-2.42057055720012	0.0207212477542719	Non-small cell lung cancer: CASP9*
hsa05231__60	0.0156363078907751	DOWN	-2.41776355616742	0.0208669194082147	Choline metabolism in cancer: PRKCA
hsa04723__9	0.0161666228710037	DOWN	-2.40559988502571	0.0215287628452275	Retrograde endocannabinoid signaling: PRKCA
hsa04725__20	0.0161666228710037	DOWN	-2.40559988502571	0.0215287628452275	Cholinergic synapse: PRKCA
hsa04726__18	0.0161666228710037	DOWN	-2.40559988502571	0.0215287628452275	Serotonergic synapse: PRKCA
hsa05321__83	0.0162495975968336	DOWN	-2.40372855100391	0.021623933345928	Inflammatory bowel disease (IBD): IL2
hsa04620__18	0.0166276322860685	UP	2.3953075479058	0.0221113383337033	Toll-like receptor signaling pathway: CXCL11
hsa04621__42	0.0169269769406828	DOWN	-2.38875787882949	0.0224934863306528	NOD-like receptor signaling pathway: MAPK8
hsa05212__27	0.0170567086372061	UP	2.38595087779679	0.0226498625648835	Pancreatic cancer: BCL2L1*
hsa04630__33	0.0175398853006313	DOWN	-2.37565854067688	0.023275031412349	Jak-STAT signaling pathway: RAF1
hsa04540__12	0.017763449411736	UP	2.37098020562238	0.0235550610054001	Gap junction: C00025
hsa04210__61	0.0178987831256663	UP	2.36817320458968	0.0237177810247721	Apoptosis: APAF1
hsa05162__78	0.0180806327311077	DOWN	-2.36443053654608	0.023941866738373	Measles: FAS
hsa05152__81	0.0182180798293584	UP	2.36162353551337	0.0241068816896932	Tuberculosis: IFNA1
hsa05210__31	0.0185423527501454	DOWN	-2.35507386643707	0.0245187057125427	Colorectal cancer: BCL2
hsa05161__97	0.0189666892072435	DOWN	-2.34665286333896	0.0250621723068991	Hepatitis B: BCL2
hsa04650__39	0.0195456658337816	DOWN	-2.33542485920815	0.0258090696427798	Natural killer cell mediated cytotoxicity: FAS
hsa05205__121	0.0195946035587615	UP	2.33448919219725	0.0258555197239556	Proteoglycans in cancer: PLAUR
hsa05010__51	0.0196436482739895	UP	2.33355352518635	0.0259020456890009	Alzheimer's disease: ATF6
hsa05161__130	0.0197420594389257	DOWN	-2.33168219116455	0.0260135551793417	Hepatitis B: FASLG*
hsa04370__36	0.0198409008583539	DOWN	-2.32981085714275	0.0261254749214065	VEGF signaling pathway: NOS3
hsa04917__46	0.0203922881738984	DOWN	-2.31951852002284	0.0268327097190162	Prolactin signaling pathway: GCK
hsa04350__32	0.0209051003225813	UP	2.31016184991383	0.0274882319846958	TGF-beta signaling pathway: RPS6KB1
hsa04010__134	0.0217489840969753	UP	2.29519117773942	0.0285778609218298	MAPK signaling pathway: ATF4*
hsa05168__10	0.0219104709989689	UP	2.29238417670672	0.0287699336177936	Herpes simplex infection: FOS
hsa04950__18	0.0219645313114836	UP	2.29144850969582	0.028820778166395	Maturity onset diabetes of the young: SLC2A2
hsa04620__23	0.0220187076316999	UP	2.29051284268492	0.0288717038659903	Toll-like receptor signaling pathway: CD40
hsa04360__81	0.0220730001610266	DOWN	-2.28957717567402	0.0289227108107175	Axon guidance: FYN*
hsa04961__26	0.0221274091011004	UP	2.28864150866312	0.028973799094751	Endocrine and other factor-regulated calcium reabsorption: TRPV5*
hsa04024__12	0.0229576503031771	DOWN	-2.27460650349961	0.0300399894983772	cAMP signaling pathway: SLC9A1
hsa04012__21	0.0241066443213015	UP	2.25589316328159	0.0314995720999482	ErbB signaling pathway: GSK3B
hsa04932__14	0.0241066443213015	UP	2.25589316328159	0.0314995720999482	Non-alcoholic fatty liver disease (NAFLD): PKLR
hsa05321__123	0.0249403110969556	DOWN	-2.24279382512898	0.0325662575060317	Inflammatory bowel disease (IBD): IL5*
hsa04720__4 15	0.0251221670862758	DOWN	-2.23998682409628	0.0327809388577169	Long-term potentiation: CREBBP ATF4
hsa04913__19	0.0254278117163218	DOWN	-2.23530848904178	0.0331567371373828	Ovarian steroidogenesis: STAR
hsa04930__26	0.0256746390393682	UP	2.23156582099818	0.0334553722295234	Type II diabetes mellitus: INS*
hsa04650__16	0.0260487650319475	DOWN	-2.22595181893277	0.0339193551594105	Natural killer cell mediated cytotoxicity: PRKCA
hsa04668__20	0.0271995530285572	DOWN	-2.20910981273656	0.0353933241971323	TNF signaling pathway: IKBKG
hsa05145__13	0.0278576416429909	UP	2.19975314262755	0.0362245734582559	Toxoplasmosis: GNAI1
hsa04910__32	0.0281246956228327	DOWN	-2.19601047458395	0.0365465443121041	Insulin signaling pathway: EIF4E
hsa04014__27	0.0283264313500539	UP	2.19320347355125	0.0367832512140644	Ras signaling pathway: ABL1
hsa04922__70	0.0286654283729783	UP	2.18852513849674	0.0371977485585817	Glucagon signaling pathway: PFKFB1
hsa04064__97	0.0289391359556782	DOWN	-2.18478247045314	0.0375270092896613	NF-kappa B signaling pathway: PLCG2
hsa05161__68	0.0295632149465305	DOWN	-2.17636146735503	0.0383098488858834	Hepatitis B: JUN
hsa04012__40	0.0296332663797626	UP	2.17542580034413	0.0383741609425044	ErbB signaling pathway: ELK1*
hsa05014__53	0.0299149014285952	DOWN	-2.17168313230053	0.0387121899341119	Amyotrophic lateral sclerosis (ALS): RAB5A
hsa04919__45	0.0300565797555511	DOWN	-2.16981179827873	0.0388687634966831	Thyroid hormone signaling pathway: SLC9A1
hsa04064__54	0.0301276349244229	UP	2.16887613126783	0.038933855586651	NF-kappa B signaling pathway: CCL13
hsa04211__51	0.0301988344040396	UP	2.16794046425693	0.0389990445671412	Longevity regulating pathway - mammal: NFKB1
hsa04062__60	0.031284301226847	UP	2.15390545909342	0.040373078300306	Chemokine signaling pathway: GSK3A
hsa04622__6	0.0317277696017416	DOWN	-2.14829145702801	0.0409172814561926	RIG-I-like receptor signaling pathway: NFKB1
hsa04923__43	0.0319515179787693	DOWN	-2.14548445599531	0.0411775735816924	Regulation of lipolysis in adipocytes: C00219
hsa04115__3	0.0325548038344429	DOWN	-2.13799911990811	0.0419263032247554	p53 signaling pathway: GADD45G
hsa04151__97	0.0341850387483771	UP	2.11835011267919	0.0439956765809593	PI3K-Akt signaling pathway: MCL1
hsa04010__129	0.0345033448596106	UP	2.11460744463559	0.0443749383923397	MAPK signaling pathway: FOS
hsa05169__103	0.0348241795628214	DOWN	-2.11086477659199	0.0447569311891528	Epstein-Barr virus infection: NFKB1*
hsa04728__60	0.0352288024795176	UP	2.10618644153748	0.045246014941226	Dopaminergic synapse: CACNA1A
hsa04630__34	0.0353102067729368	UP	2.10525077452658	0.0453195891573416	Jak-STAT signaling pathway: AOX1
hsa04970__28	0.0372221045409809	DOWN	-2.08373043327586	0.0477408426160431	Salivary secretion: AQP5
hsa04612__18	0.0373126174538205	DOWN	-2.08279476626496	0.0478242893558859	Antigen processing and presentation: KIR2DS2
hsa05221__13	0.0385247344158327	DOWN	-2.06969542811235	0.0493442235632922	Acute myeloid leukemia: NFKB1
hsa04666__49	0.0391432385587591	DOWN	-2.06314575903605	0.050068172397487	Fc gamma R-mediated phagocytosis: ARF6*
hsa05215__30	0.0391432385587591	UP	2.06314575903605	0.050068172397487	Prostate cancer: TP53
hsa04670__2	0.0398604066210147	DOWN	-2.05566042294884	0.050950819075433	Leukocyte transendothelial migration: MMP2
hsa04931__135	0.0408646930505066	UP	2.04536808582894	0.0521990198789271	Insulin resistance: SREBF1**
hsa04350__27	0.041328227735774	UP	2.04068975077443	0.0527552580947822	TGF-beta signaling pathway: ACVR2A*
hsa04750__39	0.0417022547237946	DOWN	-2.03694708273083	0.0531965625431161	Inflammatory mediator regulation of TRP channels: C01245*
hsa05162__27 28	0.0440070934760584	DOWN	-2.01449107446921	0.0560985947364408	Measles: STAT1 IRF9
hsa04620__48	0.0464185615960429	UP	1.9920350662076	0.0591325269416709	Toll-like receptor signaling pathway: CD80
hsa04726__16	0.0476654236283181	DOWN	-1.98080706207679	0.0606386804316924	Serotonergic synapse: ITPR1
hsa04726__46	0.0476654236283181	DOWN	-1.98080706207679	0.0606386804316924	Serotonergic synapse: ITPR1*
hsa04724__26	0.0478759470006741	DOWN	-1.97893572805499	0.0608652939203428	Glutamatergic synapse: PRKACA
hsa04012__24	0.0486189423800611	DOWN	-1.97238605897868	0.0617680816309227	ErbB signaling pathway: CDKN1A
hsa04550__17	0.0489403201862777	DOWN	-1.96957905794598	0.0621343659662269	Signaling pathways regulating pluripotency of stem cells: AKT3
hsa04930__9	0.05013394912025	UP	1.95928672082607	0.0636068132322416	Type II diabetes mellitus: C00238
hsa04650__119	0.0502437172745946	DOWN	-1.95835105381517	0.0637030666389766	Natural killer cell mediated cytotoxicity: KLRC4-KLRK1
hsa04015__14	0.0513519911343144	DOWN	-1.94899438370616	0.0650643232241246	Rap1 signaling pathway: MAPK14
hsa04270__28	0.0514639355011337	UP	1.94805871669526	0.0651622202201013	Vascular smooth muscle contraction: KCNMB2
hsa04010__62	0.0518009947887658	UP	1.94525171566256	0.0655448277495562	MAPK signaling pathway: MEF2C
hsa05145__35	0.0533984536114844	UP	1.93215237750995	0.0675206556769711	Toxoplasmosis: CASP3
hsa04360__21	0.054800257699315	DOWN	-1.92092437337914	0.0692465932864915	Axon guidance: PAK4
hsa04151__28	0.0549184472957712	DOWN	-1.91998870636824	0.0693493027343778	PI3K-Akt signaling pathway: BCL2L11
hsa04024__123	0.0553933330937451	DOWN	-1.91624603832464	0.0698550824719108	cAMP signaling pathway: PAK1
hsa04921__48	0.0553933330937451	DOWN	-1.91624603832464	0.0698550824719108	Oxytocin signaling pathway: PRKAG2
hsa03320__44	0.0559917478989024	DOWN	-1.91156770327014	0.0705150766099447	PPAR signaling pathway: FABP1
hsa04917__38	0.0559917478989024	DOWN	-1.91156770327014	0.0705150766099447	Prolactin signaling pathway: IRF1
hsa04151__51	0.0561120746551136	DOWN	-1.91063203625923	0.0706192821680901	PI3K-Akt signaling pathway: NOS3
hsa04650__14	0.0562326166609269	DOWN	-1.90969636924833	0.0707236189463733	Natural killer cell mediated cytotoxicity: CSF2
hsa05215__35	0.0565955369699353	UP	1.90688936821563	0.0711324508137181	Prostate cancer: CASP9
hsa04727__13	0.0570824611698739	UP	1.90314670017203	0.0716964869907707	GABAergic synapse: CACNA1A
hsa04724__33 70 69	0.0576960119983296	DOWN	-1.89846836511753	0.0724187084468011	Glutamatergic synapse: ITPR1 HOMER3 HOMER3
hsa04912__26	0.0584394994709185	DOWN	-1.89285436305212	0.0733029502709318	GnRH signaling pathway: PLD1
hsa05223__22	0.0588142172034256	DOWN	-1.89004736201942	0.0737237585892173	Non-small cell lung cancer: BAD*
hsa04210__63	0.0593169420754973	DOWN	-1.88630469397582	0.074304356106573	Apoptosis: FAS*
hsa05220__22	0.0603330923297107	DOWN	-1.87881935788861	0.0755269023900908	Chronic myeloid leukemia: CDKN1B
hsa04750__90	0.0604611197954358	DOWN	-1.87788369087771	0.0755361995316648	Inflammatory mediator regulation of TRP channels: C01245**
hsa04913__47	0.0604611197954358	UP	1.87788369087771	0.0755361995316648	Ovarian steroidogenesis: INSR
hsa04913__51	0.0604611197954358	UP	1.87788369087771	0.0755361995316648	Ovarian steroidogenesis: INSR*
hsa04917__65	0.0607178502960558	DOWN	-1.87601235685591	0.075806538675275	Prolactin signaling pathway: CYP17A1
hsa05152__77	0.0608465538976116	DOWN	-1.87507668984501	0.075916782718202	Tuberculosis: IL12A
hsa05200__53	0.0609754834446092	DOWN	-1.87414102283411	0.0760271621714803	Pathways in cancer: BCL2L1
hsa05132__6	0.0613636305946171	UP	1.87133402180141	0.0764603858669003	Salmonella infection: NFKB1
hsa05120__19	0.0628043803636174	DOWN	-1.8610416846815	0.078203731413676	Epithelial cell signaling in Helicobacter pylori infection: CXCL1
hsa04360__58	0.0634684522343487	UP	1.85636334962699	0.0789782925485703	Axon guidance: PLXNC1
hsa04921__23	0.0650859195871786	DOWN	-1.84513534549619	0.0809374208499726	Oxytocin signaling pathway: C00219
hsa04912__15	0.0661830060573936	DOWN	-1.83765000940898	0.0821929070600413	GnRH signaling pathway: CAMK2A
hsa04921__60	0.0661830060573936	DOWN	-1.83765000940898	0.0821929070600413	Oxytocin signaling pathway: ELK1
hsa04024__108	0.066598322066098	UP	1.83484300837628	0.0826540602128125	cAMP signaling pathway: AMH
hsa04115__40	0.0697099855497471	DOWN	-1.81425833413646	0.0864587873583993	p53 signaling pathway: PIDD1
hsa04012__47	0.0708706855848924	DOWN	-1.80677299804926	0.0878403814076601	ErbB signaling pathway: PRKCA
hsa05214__27	0.0724924769799308	UP	1.79648066092935	0.0897321240087549	Glioma: MTOR
hsa05214__48	0.0724924769799308	UP	1.79648066092935	0.0897321240087549	Glioma: MTOR*
hsa05145__23	0.0735402556539025	UP	1.78993099185304	0.0909691510030828	Toxoplasmosis: CIITA
hsa04210__3	0.0739930792526785	DOWN	-1.78712399082034	0.0914690762603834	Apoptosis: BCL2L1
hsa04670__35	0.0753652414969425	DOWN	-1.77870298772224	0.0931040688841255	Leukocyte transendothelial migration: PTK2
hsa04950__15	0.0755189779908718	DOWN	-1.77776732071133	0.0932326935905704	Maturity onset diabetes of the young: IAPP
hsa05142__64	0.0766023141073918	UP	1.77121765163503	0.0944460290077356	Chagas disease (American trypanosomiasis): CASP8
hsa05168__91 92	0.0766023141073918	DOWN	-1.77121765163503	0.0944460290077356	Herpes simplex infection: STAT1 IRF9
hsa05132__68	0.077698287663538	DOWN	-1.76466798255873	0.0957344803408446	Salmonella infection: NOS2
hsa04390__78	0.0817171561358442	UP	1.74127630728621	0.100620272856652	Hippo signaling pathway: SOX2
hsa04971__56	0.0828721733040515	DOWN	-1.7347266382099	0.101975647438319	Gastric acid secretion: CAMK2A
hsa04152__77	0.0830382505156322	UP	1.733790971199	0.102113136596121	AMPK signaling pathway: CCND1
hsa04071__59 60	0.0837052579260577	DOWN	-1.7300483031554	0.102866042932023	Sphingolipid signaling pathway: TP53 BCL2
hsa04976__37	0.0840403403879517	DOWN	-1.7281769691336	0.103210326528733	Bile secretion: ABCB11
hsa04010__14	0.0843765970391415	DOWN	-1.7263056351118	0.103488006420722	MAPK signaling pathway: MAPT
hsa04932__35	0.0843765970391415	DOWN	-1.7263056351118	0.103488006420722	Non-alcoholic fatty liver disease (NAFLD): PRKAG2
hsa05205__146	0.0881472254013459	UP	1.70572096087198	0.108042163424089	Proteoglycans in cancer: PTK2
hsa05133__59	0.0897284034802298	UP	1.69729995777387	0.109908520299447	Pertussis: C3
hsa05217__10	0.0920525562441893	DOWN	-1.68513628663217	0.11268192389761	Basal cell carcinoma: PTCH1*
hsa05164__90	0.0925957090785159	DOWN	-1.68232928559946	0.113273006092794	Influenza A: MAPK1
hsa03320__42	0.0929592384161212	UP	1.68045795157766	0.113643727380541	PPAR signaling pathway: ACOX1
hsa05169__64	0.0935066794044679	UP	1.67765095054496	0.114238654486993	Epstein-Barr virus infection: NFKB2
hsa04010__117	0.0936897334240049	UP	1.67671528353406	0.114313642275133	MAPK signaling pathway: JUND
hsa04370__16	0.0936897334240049	DOWN	-1.67671528353406	0.114313642275133	VEGF signaling pathway: HSPB1
hsa05142__67	0.0940567037400114	UP	1.67484394951226	0.114686921692071	Chagas disease (American trypanosomiasis): IFNGR1*
hsa04742__34	0.0944248256932883	UP	1.67297261549046	0.115061120283845	Taste transduction: GRM1
hsa05213__13	0.0947941016047724	DOWN	-1.67110128146865	0.115436239089674	Endometrial cancer: CASP9
hsa04340__51	0.0998934418877439	DOWN	-1.64583827217434	0.121565867763968	Hedgehog signaling pathway: CCND1*
hsa04151__73	0.100086427584278	DOWN	-1.64490260516344	0.121565867763968	PI3K-Akt signaling pathway: MAPK1
hsa04620__12	0.100086427584278	DOWN	-1.64490260516344	0.121565867763968	Toll-like receptor signaling pathway: NFKB1
hsa05161__48	0.100086427584278	DOWN	-1.64490260516344	0.121565867763968	Hepatitis B: STAT1
hsa04210__24	0.100667168814415	UP	1.64209560413073	0.12219225465264	Apoptosis: CASP10
hsa04010__12	0.102228946460691	UP	1.63461026804353	0.124007869851283	MAPK signaling pathway: PLA2G4B
hsa04520__18	0.103017033990913	UP	1.63086759999992	0.124883230238016	Adherens junction: SNAI2
hsa05200__48	0.105410311807722	UP	1.61963959586912	0.127702112112643	Pathways in cancer: MTOR
hsa04932__97	0.106623385148066	DOWN	-1.61402559380371	0.129088492714701	Non-alcoholic fatty liver disease (NAFLD): TNF*
hsa04072__27	0.106826635566152	UP	1.61308992679281	0.129168113403346	Phospholipase D signaling pathway: C01245
hsa04921__28	0.106826635566152	UP	1.61308992679281	0.129168113403346	Oxytocin signaling pathway: EEF2
hsa04150__33	0.109289661093782	UP	1.601861922662	0.132061268935831	mTOR signaling pathway: RPS6
hsa04340__31	0.112643291879582	DOWN	-1.58689125048759	0.135938821735218	Hedgehog signaling pathway: GLI1***
hsa05223__37	0.112643291879582	DOWN	-1.58689125048759	0.135938821735218	Non-small cell lung cancer: CCND1*
hsa04622__5 33	0.114350260229655	DOWN	-1.57940591440039	0.137910230405342	RIG-I-like receptor signaling pathway: MAVS TMEM173
hsa04726__71	0.115427411910221	UP	1.57472757934588	0.13912001730552	Serotonergic synapse: CACNA1A
hsa04917__40	0.118927976636134	UP	1.55975690717147	0.143247223140574	Prolactin signaling pathway: TH
hsa05211__27	0.120933303574797	DOWN	-1.55133590407336	0.14556930007498	Renal cell carcinoma: VEGFA*
hsa04115__23	0.125023240725876	UP	1.53449389787715	0.150396075111346	p53 signaling pathway: PTEN
hsa04020__18	0.126875185329518	UP	1.52700856178995	0.152331292801383	Calcium signaling pathway: C00002
hsa04020__17	0.126875185329518	UP	1.52700856178995	0.152331292801383	Calcium signaling pathway: C00004
hsa04020__15	0.126875185329518	UP	1.52700856178995	0.152331292801383	Calcium signaling pathway: C13051
hsa04210__107	0.127108219727534	UP	1.52607289477905	0.152416339141961	Apoptosis: MCL1
hsa03320__32	0.127108250896995	DOWN	-1.52607289477905	0.152416339141961	PPAR signaling pathway: FABP3
hsa05145__8	0.133525821765911	DOWN	-1.50080988548473	0.160009578506471	Toxoplasmosis: NFKB1
hsa05221__41	0.133768238191181	DOWN	-1.49987421847383	0.160197909216844	Acute myeloid leukemia: MAPK1
hsa04340__52	0.136211164548589	DOWN	-1.49051754836482	0.163019603940637	Hedgehog signaling pathway: BCL2*
hsa04064__2	0.140442991900523	DOWN	-1.47461120917951	0.167977327677328	NF-kappa B signaling pathway: BCL2L1
hsa04210__51	0.140947430021365	UP	1.47273987515771	0.168473423034444	Apoptosis: LMNA
hsa04350__41	0.14145325984197	UP	1.4708685411359	0.168970550059162	TGF-beta signaling pathway: SMAD4***
hsa05217__22	0.14272393661048	DOWN	-1.4661902060814	0.170380099676678	Basal cell carcinoma: LEF1
hsa05162__28 34	0.144517579719024	UP	1.4596405370051	0.172411766534633	Measles: IRF9 STAT1
hsa05200__186	0.145033208979905	DOWN	-1.45776920298329	0.172917131772361	Pathways in cancer: PTCH1*
hsa04919__87	0.145550246330838	UP	1.45589786896149	0.173423533833637	Thyroid hormone signaling pathway: BAD
hsa04012__35	0.146588553417267	DOWN	-1.45215520091789	0.174549994848571	ErbB signaling pathway: CBLC
hsa05164__24	0.147370995032534	DOWN	-1.44934819988519	0.175370550770191	Influenza A: IRF7
hsa04530__4 53	0.149209104249976	UP	1.44279853080888	0.177445510687154	Tight junction: OCLN OCLN
hsa04012__57	0.152669086769649	DOWN	-1.43063485966717	0.181445423175313	ErbB signaling pathway: ABL1
hsa05200__75	0.153206767258402	UP	1.42876352564537	0.181969352514878	Pathways in cancer: MAPK8
hsa04722__33	0.154828450818451	DOWN	-1.42314952357997	0.183779317174901	Neurotrophin signaling pathway: BAD
hsa05212__12	0.156189785257028	DOWN	-1.41847118852547	0.185278160667902	Pancreatic cancer: CASP9
hsa05219__19	0.158110882627161	DOWN	-1.41192151944916	0.187438705650748	Bladder cancer: TP53
hsa04621__4 7 8	0.163698323453423	UP	1.39320817923115	0.193940195314617	NOD-like receptor signaling pathway: IKBKG CHUK IKBKB
hsa04115__25	0.164549118950241	DOWN	-1.39040117819844	0.194825327351923	p53 signaling pathway: CD82
hsa04924__52	0.164833456228637	DOWN	-1.38946551118754	0.195039083283129	Renin secretion: KCNJ2
hsa04261__62	0.165403240345075	DOWN	-1.38759417716574	0.195590112403018	Adrenergic signaling in cardiomyocytes: BCL2
hsa04510__6 4 5	0.16568868764539	UP	1.38665851015484	0.195804430242572	Focal adhesion: FLNA ITGB1 ITGA11
hsa04932__56	0.168563574320896	UP	1.37730184004583	0.199076653770561	Non-alcoholic fatty liver disease (NAFLD): CASP7
hsa05014__54	0.170014981735018	DOWN	-1.37262350499133	0.200664667512625	Amyotrophic lateral sclerosis (ALS): PPP3CA
hsa05223__8	0.171475736272	DOWN	-1.36794516993683	0.202261712777833	Non-small cell lung cancer: CASP9
hsa03320__65	0.172651088666642	UP	1.36420250189322	0.203520323465885	PPAR signaling pathway: ME1
hsa04064__53	0.175019850602119	UP	1.35671716580602	0.206183259737544	NF-kappa B signaling pathway: CXCL8
hsa04621__6	0.176812277505467	DOWN	-1.35110316374061	0.207903798143162	NOD-like receptor signaling pathway: NFKB1
hsa04919__89	0.176812277505467	UP	1.35110316374061	0.207903798143162	Thyroid hormone signaling pathway: CASP9
hsa05168__9	0.176812277505467	DOWN	-1.35110316374061	0.207903798143162	Herpes simplex infection: NFKB1
hsa04151__32	0.177412782532533	DOWN	-1.34923182971881	0.208479436134228	PI3K-Akt signaling pathway: BCL2L1
hsa04919__38	0.179829995639588	UP	1.34174649363161	0.211187851129242	Thyroid hormone signaling pathway: TP53
hsa04913__40	0.180133860023301	DOWN	-1.34081082662071	0.211412569009233	Ovarian steroidogenesis: HSD17B1
hsa04610__17	0.180438105726841	UP	1.33987515960981	0.211637453595964	Complement and coagulation cascades: PLG
hsa05166__39	0.182271599498478	DOWN	-1.3342611575444	0.213654607272389	HTLV-I infection: RRAS2
hsa04520__44 52 45	0.183193511268839	DOWN	-1.3314541565117	0.214601376355455	Adherens junction: ACTB ACTN4 CTNNA1
hsa04064__132	0.18411887381522	UP	1.328647155479	0.215551005544423	NF-kappa B signaling pathway: VCAM1
hsa04921__67	0.184737702043117	DOWN	-1.3267758214572	0.216006311225275	Oxytocin signaling pathway: RYR1
hsa05152__23	0.184737702043117	DOWN	-1.3267758214572	0.216006311225275	Tuberculosis: PPP3CA
hsa04064__131	0.185358068088344	DOWN	-1.3249044874354	0.216596896727611	NF-kappa B signaling pathway: CCL4L1
hsa04390__94	0.185668828306375	DOWN	-1.32396882042449	0.216825188556668	Hippo signaling pathway: GLI2
hsa05205__142	0.185979973594602	DOWN	-1.32303315341359	0.217053646201402	Proteoglycans in cancer: CTNNB1
hsa04913__12	0.186915721922479	DOWN	-1.32022615238089	0.217875087774403	Ovarian steroidogenesis: HSD3B1
hsa05222__19	0.186915721922479	UP	1.32022615238089	0.217875087774403	Small cell lung cancer: CASP9
hsa05200__187	0.189743826510457	UP	1.31180514928279	0.221034500938096	Pathways in cancer: WNT16*
hsa04917__56	0.19037655369908	UP	1.30993381526098	0.221634166295274	Prolactin signaling pathway: LHCGR
hsa04919__18	0.193563506667246	UP	1.30057714515198	0.225204847695205	Thyroid hormone signaling pathway: STAT1
hsa04919__39	0.200054618460775	DOWN	-1.28186380493396	0.232613012430566	Thyroid hormone signaling pathway: ESR1
hsa04611__92	0.202363648373751	DOWN	-1.27531413585766	0.235152316199307	Platelet activation: RHOA*
hsa04015__3	0.206703258469359	UP	1.26315046471595	0.240046614749027	Rap1 signaling pathway: MAPK1
hsa05212__14	0.210087104148082	UP	1.25379379460694	0.243825613770381	Pancreatic cancer: MAPK1
hsa05213__12	0.211793984711703	DOWN	-1.24911545955244	0.245654874860055	Endometrial cancer: BAD
hsa04115__37	0.212822911741583	DOWN	-1.24630845851974	0.246696021691816	p53 signaling pathway: FAS
hsa04072__57	0.219774754218696	UP	1.22759511830172	0.254597264597368	Phospholipase D signaling pathway: C06124
hsa04015__11	0.221891739564162	DOWN	-1.22198111623632	0.256891299224313	Rap1 signaling pathway: RAC1
hsa04115__30	0.223311154015145	UP	1.21823844819271	0.258375405415306	p53 signaling pathway: SERPINE1
hsa04917__68	0.223667020383285	DOWN	-1.21730278118181	0.258627896184734	Prolactin signaling pathway: CCND1
hsa04668__102	0.224379969478715	DOWN	-1.21543144716001	0.25929271995726	TNF signaling pathway: AKT3
hsa05145__4 5	0.226169444587909	DOWN	-1.21075311210551	0.261199991629184	Toxoplasmosis: MAP3K7 TAB1
hsa04213__13	0.227248005741214	UP	1.20794611107281	0.262123390293273	Longevity regulating pathway - multiple species: RPS6KB1*
hsa04919__11	0.227248005741214	UP	1.20794611107281	0.262123390293273	Thyroid hormone signaling pathway: CTNNB1
hsa05200__49	0.229778895720747	UP	1.2013964419965	0.264880088993426	Pathways in cancer: CASP9
hsa05321__92	0.231234088617385	UP	1.1976537739529	0.266394146236706	Inflammatory bowel disease (IBD): IL17F
hsa05215__46	0.237863450991145	DOWN	-1.18081176775669	0.273863617899731	Prostate cancer: MTOR
hsa05218__9	0.238608249415286	UP	1.17894043373489	0.27455290915574	Melanoma: CCND1
hsa04622__44	0.241603896448333	UP	1.17145509764768	0.277829694875409	RIG-I-like receptor signaling pathway: MAPK8
hsa05169__31	0.241980205385604	DOWN	-1.17051943063678	0.278092236036421	Epstein-Barr virus infection: MYC
hsa04010__86	0.242356926523439	DOWN	-1.16958376362588	0.278354929668424	MAPK signaling pathway: MAP4K2
hsa04115__50	0.242734059983184	UP	1.16864809661498	0.278617775631278	p53 signaling pathway: RCHY1
hsa04151__99	0.243111605885594	DOWN	-1.16771242960408	0.278880773784513	PI3K-Akt signaling pathway: MYB
hsa04510__26 4 5	0.244625916316323	UP	1.16396976156047	0.280446672823899	Focal adhesion: ACTN4 ITGB1 ITGA11
hsa05130__26	0.245765966259456	DOWN	-1.16116276052777	0.281581860122877	Pathogenic Escherichia coli infection: CTNNB1
hsa04540__1	0.246909649474497	DOWN	-1.15835575949507	0.282719824108824	Gap junction: C00681
hsa04912__33	0.25152220062201	DOWN	-1.14712775536426	0.28782595308694	GnRH signaling pathway: ELK1
hsa04152__56	0.257371800461461	DOWN	-1.13309275020075	0.294340604423059	AMPK signaling pathway: FASN
hsa04724__67	0.262118949768292	DOWN	-1.12186474606994	0.299587291128115	Glutamatergic synapse: PLD1
hsa04390__95	0.26411467208458	UP	1.11718641101544	0.301684783493572	Hippo signaling pathway: AFP
hsa04620__22	0.266926247907364	UP	1.11063674193913	0.3047110691482	Toll-like receptor signaling pathway: CD86
hsa05133__60	0.271385903959588	DOWN	-1.10034440481923	0.30961391228905	Pertussis: C5
hsa04932__31 133	0.274661016431316	UP	1.09285906873202	0.313160224438375	Non-alcoholic fatty liver disease (NAFLD): PPARA RXRA
hsa05215__34	0.276721870991211	UP	1.08818073367752	0.315318614671004	Prostate cancer: BAD
hsa03320__57	0.277135271712534	DOWN	-1.08724506666662	0.315598288210818	PPAR signaling pathway: APOC3
hsa04914__23	0.288881471804135	DOWN	-1.0610463903614	0.328775460642017	Progesterone-mediated oocyte maturation: PRKACA
hsa04390__17 51	0.292727270134751	DOWN	-1.05262538726329	0.332950690425665	Hippo signaling pathway: YWHAQ YAP1
hsa05222__34	0.297040522008769	DOWN	-1.04326871715428	0.337652232821825	Small cell lung cancer: CCND1
hsa04012__65	0.29964877061083	DOWN	-1.03765471508888	0.340411148716898	ErbB signaling pathway: MYC
hsa05160__70	0.303589704403837	DOWN	-1.02923371199077	0.344679791283872	Hepatitis C: CDKN1A
hsa04210__106	0.305793927454335	UP	1.02455537693627	0.346972699086168	Apoptosis: TUBA1B
hsa04151__63	0.309788206623351	DOWN	-1.01613437383816	0.351292721934385	PI3K-Akt signaling pathway: CASP9
hsa04014__33	0.310680483170713	DOWN	-1.01426303981636	0.352092055414819	Ras signaling pathway: BCL2L1
hsa05020__48	0.311127256834639	DOWN	-1.01332737280546	0.35238584423887	Prion diseases: SOD1
hsa05200__184	0.312470119511134	UP	1.01052037177276	0.353693587085193	Pathways in cancer: GLI1
hsa04152__30	0.314266533994038	UP	1.00677770372916	0.355512834060684	AMPK signaling pathway: ACACA
hsa04919__30	0.3196964494867	DOWN	-0.995549699598348	0.361437802999705	Thyroid hormone signaling pathway: MYH6
hsa04150__56	0.320607366818999	UP	0.993678365576546	0.362249694680036	mTOR signaling pathway: EIF4B
hsa04510__20 4 5	0.324267981905656	DOWN	-0.986193029489341	0.366165587740822	Focal adhesion: VASP ITGB1 ITGA11
hsa04621__44	0.327955706547701	DOWN	-0.978707693402135	0.37010737093281	NOD-like receptor signaling pathway: MAPK14
hsa04911__24	0.328418577934659	DOWN	-0.977772026391234	0.370407267670603	Insulin secretion: INS
hsa04014__45	0.3293455910629	UP	0.975900692369433	0.371229973369639	Ras signaling pathway: RAB5A
hsa04530__20 37	0.329809732766277	DOWN	-0.974965025358532	0.371530268505895	Tight junction: ACTB TJP3
hsa04064__36	0.334474433088321	UP	0.965608355249525	0.376559292853777	NF-kappa B signaling pathway: PLCG1
hsa04910__18	0.345363775951041	DOWN	-0.944088013998809	0.388585949108985	Insulin signaling pathway: LIPE
hsa05200__220	0.347280393375372	DOWN	-0.940345345955206	0.390508593149206	Pathways in cancer: CSF1R*
hsa04650__36	0.356964720527767	UP	0.921632005737192	0.40115831930124	Natural killer cell mediated cytotoxicity: CASP3
hsa04961__20	0.358431481641077	DOWN	-0.91882500470449	0.402565901974646	Endocrine and other factor-regulated calcium reabsorption: CALB1*
hsa04152__57	0.35990287701811	UP	0.916018003671788	0.403735824428077	AMPK signaling pathway: ACACA*
hsa05162__62	0.35990287701811	DOWN	-0.916018003671788	0.403735824428077	Measles: IL12A
hsa05223__9	0.368309823716745	DOWN	-0.900111664486476	0.412920142460479	Non-small cell lung cancer: BAD
hsa05030__80 81	0.370805532896473	DOWN	-0.895433329431972	0.415470242285314	Cocaine addiction: GRIN3A DLG4
hsa03320__22	0.374317115039782	DOWN	-0.888883660355667	0.418905216890857	PPAR signaling pathway: ACADM
hsa04015__18	0.374317115039782	DOWN	-0.888883660355667	0.418905216890857	Rap1 signaling pathway: CDH1
hsa04915__40	0.37633293631131	DOWN	-0.885140992312065	0.420910468648186	Estrogen signaling pathway: CREB3**
hsa05200__76	0.378355443097676	UP	0.881398324268462	0.422920807602934	Pathways in cancer: RAC1
hsa03320__45	0.379876706803733	DOWN	-0.87859132323576	0.424368806233184	PPAR signaling pathway: PDPK1
hsa03320__26	0.381910898073322	UP	0.874848655192157	0.426134547197014	PPAR signaling pathway: CPT2
hsa05205__215 216	0.381910898073322	DOWN	-0.874848655192157	0.426134547197014	Proteoglycans in cancer: EIF4B RPS6
hsa04725__53	0.382420283157029	DOWN	-0.873912988181256	0.426449680743061	Cholinergic synapse: CHRNA7
hsa04510__43	0.385486773145114	DOWN	-0.868298986115852	0.429614262597668	Focal adhesion: BAD
hsa05100__24	0.38599927725499	DOWN	-0.867363319104951	0.429930433883893	Bacterial invasion of epithelial cells: ACTB
hsa05132__48	0.386512197238633	DOWN	-0.866427652094051	0.430246693490161	Salmonella infection: KLC3
hsa04630__35	0.395815739762653	DOWN	-0.849585645897838	0.440342081121388	Jak-STAT signaling pathway: MTOR
hsa04976__38	0.39999370495595	UP	0.842100309810632	0.444726728764633	Bile secretion: ABCC2
hsa04668__128	0.400517808524206	UP	0.841164642799732	0.445046104208742	TNF signaling pathway: CHUK*
hsa05220__25	0.403671086176939	DOWN	-0.835550640734327	0.448284852793421	Chronic myeloid leukemia: BCL2L1*
hsa04917__45	0.405253283543665	UP	0.832743639701625	0.449776089650648	Prolactin signaling pathway: SLC2A2
hsa04210__62	0.411086305336508	UP	0.822451302581718	0.455980618493092	Apoptosis: TP53AIP1
hsa05110__50	0.412152127483692	DOWN	-0.820579968559916	0.456893125393427	Vibrio cholerae infection: ACTB
hsa05321__75	0.412685738770845	DOWN	-0.819644301549015	0.457214919310388	Inflammatory bowel disease (IBD): IL10
hsa04930__10	0.416968884154078	DOWN	-0.81215896546181	0.461687998423991	Type II diabetes mellitus: C00031
hsa04720__32	0.417506114348712	DOWN	-0.811223298450909	0.461738663249694	Long-term potentiation: ITPR1
hsa05210__40	0.417506114348712	UP	0.811223298450909	0.461738663249694	Colorectal cancer: CASP9
hsa04728__32	0.419120250460455	DOWN	-0.808416297418207	0.463251147420703	Dopaminergic synapse: CREB3
hsa04610__45	0.425613398726681	UP	0.797188293287399	0.470151426341818	Complement and coagulation cascades: C4A
hsa05032__30	0.426701166399527	UP	0.795316959265597	0.471076082059172	Morphine addiction: ADORA1
hsa05161__31	0.428881871119868	DOWN	-0.791574291221994	0.473205540712995	Hepatitis B: ELK1
hsa04911__56	0.431068937568628	UP	0.787831623178392	0.475339515077143	Insulin secretion: CAMK2A*
hsa04662__27	0.432164891936825	UP	0.78596028915659	0.476268523137416	B cell receptor signaling pathway: NFATC1
hsa04612__39	0.437116615468758	UP	0.777539286058484	0.481443212465297	Antigen processing and presentation: PSME3
hsa05120__53	0.439881628962295	UP	0.77286095100398	0.48420479251327	Epithelial cell signaling in Helicobacter pylori infection: GIT1
hsa05215__22	0.441625796431522	DOWN	-0.70642859323003	0.485840088697207	Prostate cancer: C16038
hsa04910__39	0.447117446464476	DOWN	-0.760697279862271	0.491593728441633	Insulin signaling pathway: BAD
hsa05032__31	0.448796813176695	DOWN	-0.757890278829569	0.492575474275123	Morphine addiction: GABRR3
hsa05032__33	0.448796813176695	DOWN	-0.757890278829569	0.492575474275123	Morphine addiction: GABRR3*
hsa05032__55	0.448796813176695	DOWN	-0.757890278829569	0.492575474275123	Morphine addiction: GABRR3**
hsa04931__46	0.457247146187863	UP	0.743855273666059	0.501557144008754	Insulin resistance: PIK3R5*
hsa04931__144	0.460083655707972	DOWN	-0.739176938611555	0.504374089308798	Insulin resistance: C00533*
hsa04115__27	0.463500426655811	UP	0.733562936546151	0.507823499525521	p53 signaling pathway: THBS1
hsa04064__4	0.468651987963136	DOWN	-0.725141933448045	0.513168464675252	NF-kappa B signaling pathway: BIRC2
hsa04210__99	0.470376191068916	UP	0.722334932415342	0.514756472346239	Apoptosis: BID**
hsa04510__23 4 5	0.474991145924989	UP	0.714849596328137	0.519202072829002	Focal adhesion: TLN1 ITGB1 ITGA11
hsa05222__32	0.474991145924989	UP	0.714849596328137	0.519202072829002	Small cell lung cancer: BIRC8
hsa04920__1	0.476728140128115	DOWN	-0.712042595295435	0.520797776337633	Adipocytokine signaling pathway: C00195
hsa05145__9	0.477307910290465	DOWN	-0.711106928284534	0.521128160044034	Toxoplasmosis: MAPK1
hsa04210__31 32 33	0.479049533548736	DOWN	-0.708299927251832	0.522725942821181	Apoptosis: TRAF2 RIPK1 TRADD
hsa05162__27 70	0.482543164707822	UP	0.702685925186428	0.526232505215321	Measles: STAT1 GNB2L1
hsa04921__11	0.488983955939621	UP	0.69239358806652	0.532947130632568	Oxytocin signaling pathway: PRKACA
hsa04024__62	0.490159964910492	DOWN	-0.690522254044719	0.533609834337668	cAMP signaling pathway: BAD
hsa05200__96	0.490159964910492	DOWN	-0.690522254044719	0.533609834337668	Pathways in cancer: C00416
hsa05221__26	0.491337493468472	UP	0.688650920022917	0.534582020976989	Acute myeloid leukemia: BAD
hsa04961__17	0.493106630790893	UP	0.685843918990215	0.536196388458384	Endocrine and other factor-regulated calcium reabsorption: CALB1
hsa04932__28	0.494879174944422	UP	0.683036917957513	0.537812590931504	Non-alcoholic fatty liver disease (NAFLD): GSK3A
hsa04650__35	0.496655118496445	DOWN	-0.680229916924811	0.539430617141515	Natural killer cell mediated cytotoxicity: BID
hsa04330__12	0.497247853807913	DOWN	-0.67929424991391	0.53976240167826	Notch signaling pathway: HES1
hsa04932__7	0.515203745237289	DOWN	-0.651224239586889	0.558930621998191	Non-alcoholic fatty liver disease (NAFLD): SREBF1
hsa04015__92	0.51762289772636	UP	0.647481571543286	0.561231058758125	Rap1 signaling pathway: C00076*
hsa05205__236	0.520655432108231	UP	0.642803236488783	0.564193516108054	Proteoglycans in cancer: ITGAV
hsa04014__79	0.522479243107387	DOWN	-0.639996235456081	0.56551756785644	Ras signaling pathway: RAC1**
hsa05321__94	0.522479243107387	DOWN	-0.639996235456081	0.56551756785644	Inflammatory bowel disease (IBD): IL22
hsa05222__39	0.528582232012572	DOWN	-0.630639565347074	0.57179390555649	Small cell lung cancer: BCL2L1
hsa04728__71 72	0.530420181184918	DOWN	-0.627832564314372	0.573451968035938	Dopaminergic synapse: CLOCK ARNTL
hsa05110__46	0.532875817784693	DOWN	-0.624089896270769	0.575775538595422	Vibrio cholerae infection: PLCG1
hsa04066__63	0.534721312060603	UP	0.621282895238067	0.577105884756963	HIF-1 signaling pathway: TIMP1*
hsa04066__57	0.534721312060603	UP	0.621282895238067	0.577105884756963	HIF-1 signaling pathway: TIMP1
hsa04530__4 45	0.535337192552916	UP	0.620347228227166	0.577438912059087	Tight junction: OCLN TJP2
hsa05218__14	0.535953430359931	UP	0.619411561216265	0.577771942424734	Melanoma: BAD
hsa05231__18	0.5390399674491	DOWN	-0.614733226161762	0.580766111718382	Choline metabolism in cancer: CHKA
hsa04670__86	0.54275553332555	UP	0.609119224096357	0.584434181729919	Leukocyte transendothelial migration: ACTB
hsa04917__71	0.545239647179153	UP	0.605376556052755	0.58677279327012	Prolactin signaling pathway: CCND1*
hsa05212__31	0.547106428683562	UP	0.602569555020052	0.588444750713459	Pancreatic cancer: RAC1*
hsa04921__76	0.548352704551633	DOWN	-0.600698220998251	0.589110767211275	Oxytocin signaling pathway: CDKN1A
hsa05130__55	0.548352704551633	UP	0.600698220998251	0.589110767211275	Pathogenic Escherichia coli infection: ACTB
hsa03320__56	0.550224743683814	DOWN	-0.597891219965549	0.590784167646792	PPAR signaling pathway: FADS2
hsa04530__4 37 11	0.558373097796346	DOWN	-0.58572754882384	0.599190777132686	Tight junction: OCLN TJP3 TJP1
hsa04920__9	0.565946342553919	DOWN	-0.574499544693031	0.606970991814392	Adipocytokine signaling pathway: G6PC
hsa04115__9	0.568481671128617	UP	0.570756876649429	0.609342304649555	p53 signaling pathway: RPRM
hsa05169__117	0.569751368361138	DOWN	-0.568885542627627	0.610355086174788	Epstein-Barr virus infection: CDKN1A
hsa04668__47	0.575481684493363	UP	0.560464539529521	0.616142498668393	TNF signaling pathway: CASP7
hsa05142__49	0.578676915356756	DOWN	-0.555786204475017	0.619210662844729	Chagas disease (American trypanosomiasis): ADCY1
hsa04914__42	0.581239086927821	UP	0.552043536431415	0.621598317778813	Progesterone-mediated oocyte maturation: ARAF
hsa04066__50	0.589602580836135	DOWN	-0.539879865289705	0.62982561079653	HIF-1 signaling pathway: TF
hsa04152__52	0.589602580836135	UP	0.539879865289705	0.62982561079653	AMPK signaling pathway: PCK1
hsa04014__43	0.590248218111368	DOWN	-0.538944198278805	0.630157046495035	Ras signaling pathway: ELK1
hsa04014__104	0.594128860574378	DOWN	-0.5333301962134	0.63393988019265	Ras signaling pathway: BRAP*
hsa04920__2	0.59737161419191	DOWN	-0.528651861158897	0.637007767540336	Adipocytokine signaling pathway: C00638
hsa04917__44	0.59802112929279	UP	0.527716194147996	0.637007767540336	Prolactin signaling pathway: PRLR**
hsa05205__69	0.59802112929279	DOWN	-0.527716194147996	0.637007767540336	Proteoglycans in cancer: MAPK1*
hsa05020__46	0.598670964897266	DOWN	-0.526780527137096	0.637338664613011	Prion diseases: PRKACA
hsa05152__6	0.617653744973529	DOWN	-0.499646183820975	0.657175190716456	Tuberculosis: IL10
hsa03320__20	0.6189725647252	DOWN	-0.497774849799174	0.658205687107329	PPAR signaling pathway: SCP2
hsa05321__122	0.620292612377763	UP	0.495903515777372	0.659236322770258	Inflammatory bowel disease (IBD): IL4**
hsa05161__29	0.624922398478724	UP	0.489353846701067	0.663781337897978	Hepatitis B: NFKB1
hsa05010__50	0.637563369711924	DOWN	-0.471576173493954	0.676825746716782	Alzheimer's disease: ERN1
hsa05210__39	0.641577490718087	UP	0.46596217142855	0.680702487328789	Colorectal cancer: BAD
hsa04725__43	0.644259412933601	UP	0.462219503384947	0.683162210441443	Cholinergic synapse: CREB3
hsa04723__46	0.647618335619179	UP	0.457541168330444	0.686336634308199	Retrograde endocannabinoid signaling: ADCY1
hsa05212__10	0.652332893835771	DOWN	-0.450991499254139	0.690943352602826	Pancreatic cancer: BCL2L1
hsa04931__40	0.662482224648708	UP	0.436956494090628	0.701298084571787	Insulin resistance: PRKCZ
hsa04210__105	0.669964796261782	UP	0.42666415697072	0.708819736585523	Apoptosis: ACTB
hsa04713__56	0.682279659382738	DOWN	-0.409822150774508	0.721442588621365	Circadian entrainment: KCNJ3
hsa04976__36	0.685027968091636	UP	0.406079482730905	0.723941255367933	Bile secretion: SLC10A1
hsa05142__18	0.687780452088384	DOWN	-0.402336814687302	0.726441523032081	Chagas disease (American trypanosomiasis): FOS
hsa03320__25	0.688469221698206	UP	0.401401147676401	0.726760487399398	PPAR signaling pathway: EHHADH
hsa05169__29	0.697446559077626	DOWN	-0.389237476534692	0.735823742002729	Epstein-Barr virus infection: FCER2
hsa04062__42	0.710643512761301	UP	0.371459803327579	0.749326128214638	Chemokine signaling pathway: PAK1
hsa04012__48	0.715527752694919	DOWN	-0.364910134251274	0.754053083182139	ErbB signaling pathway: CAMK2A
hsa04370__38	0.720423665077982	UP	0.358360465174969	0.758787032893233	VEGF signaling pathway: BAD
hsa04723__7	0.722525441233811	UP	0.355553464142267	0.760460320681676	Retrograde endocannabinoid signaling: ITPR1
hsa04064__137	0.723226499764851	DOWN	-0.354617797131366	0.760460320681676	NF-kappa B signaling pathway: ICAM1
hsa04151__96	0.723226499764851	DOWN	-0.354617797131366	0.760460320681676	PI3K-Akt signaling pathway: BCL2
hsa04022__9	0.724629313327005	UP	0.352746463109565	0.76150921685763	cGMP-PKG signaling pathway: ITPR1
hsa04064__115	0.72673526685428	DOWN	-0.349939462076863	0.763295453560197	NF-kappa B signaling pathway: XIAP
hsa04742__55	0.728139539503009	DOWN	-0.348068128055061	0.764343125545338	Taste transduction: P2RX3
hsa05164__41 42	0.728843287265187	UP	0.347132461044161	0.764654682731037	Influenza A: STAT1 IRF9
hsa05164__53	0.730249775267844	DOWN	-0.345261127022359	0.76570274984837	Influenza A: MAPK14
hsa05161__57	0.740120365449414	DOWN	-0.332161788869749	0.77561972486305	Hepatitis B: STAT3*
hsa04024__107 64	0.747906056942077	DOWN	-0.321869451749842	0.782905560442431	cAMP signaling pathway: NFKBIA NFKB1
hsa05220__15	0.747906056942077	UP	0.321869451749842	0.782905560442431	Chronic myeloid leukemia: MYC
hsa04931__77	0.757852086020668	UP	0.308770113597232	0.792875317167503	Insulin resistance: PPP2R4**
hsa04912__14	0.759988964998642	DOWN	-0.30596311256453	0.794668483713104	GnRH signaling pathway: ATF4
hsa04621__28	0.762127431769006	DOWN	-0.303156111531828	0.79646131495771	NOD-like receptor signaling pathway: CASP8
hsa04110__96 97	0.765695574841228	UP	0.298477776477324	0.799745405851399	Cell cycle: TFDP1 E2F4
hsa04151__35	0.767124229936301	UP	0.296606442455523	0.80079246002795	PI3K-Akt signaling pathway: CCND1
hsa05214__23	0.770699322426804	UP	0.291928107401019	0.803631535427283	Glioma: MAPK1
hsa05214__56	0.770699322426804	UP	0.291928107401019	0.803631535427283	Glioma: MAPK1*
hsa04750__51	0.774279261538492	UP	0.287249772346516	0.806469363875181	Inflammatory mediator regulation of TRP channels: TRPV4
hsa04750__61	0.774279261538492	UP	0.287249772346516	0.806469363875181	Inflammatory mediator regulation of TRP channels: TRPV4*
hsa05169__60	0.77858159579925	DOWN	-0.281635770281111	0.810501284491297	Epstein-Barr virus infection: NFKB1
hsa04152__53	0.782890694984242	UP	0.276021768215707	0.814535778447061	AMPK signaling pathway: G6PC
hsa05169__79	0.78360953015799	UP	0.275086101204807	0.814832488747572	Epstein-Barr virus infection: ATF2
hsa04742__47	0.796579561595607	DOWN	-0.258244095008594	0.827403561201366	Taste transduction: GABRA1
hsa04550__67	0.796579586063476	DOWN	-0.258244095008594	0.827403561201366	Signaling pathways regulating pluripotency of stem cells: MYC*
hsa05200__225	0.811056792752736	DOWN	-0.23953075479058	0.841510609377356	Pathways in cancer: PPARD
hsa05221__11	0.811056792752736	DOWN	-0.23953075479058	0.841510609377356	Acute myeloid leukemia: PPARD
hsa04742__31	0.813234089324933	DOWN	-0.236723753757878	0.843304003223813	Taste transduction: C00076*
hsa04110__46	0.813960176626419	UP	0.235788086746977	0.84359137996748	Cell cycle: RB1
hsa05205__400	0.814686401440425	UP	0.234852419736076	0.843700830464067	Proteoglycans in cancer: ITGA2*
hsa04913__36	0.81541283029417	UP	0.233916752725176	0.843700830464067	Ovarian steroidogenesis: CYP19A1
hsa04913__37	0.81541283029417	UP	0.233916752725176	0.843700830464067	Ovarian steroidogenesis: CYP19A1*
hsa05164__70	0.819774580510755	UP	0.228302750659771	0.84728076830567	Influenza A: RNASEL
hsa05168__83	0.819774580510755	UP	0.228302750659771	0.84728076830567	Herpes simplex infection: RNASEL
hsa04064__136	0.836545193529619	UP	0.206782409409055	0.864138767807672	NF-kappa B signaling pathway: TNFSF13B*
hsa04726__39	0.839469649020118	DOWN	-0.203039741365452	0.866683225554287	Serotonergic synapse: CACNA1C
hsa04024__44 67	0.847523220005214	DOWN	-0.192747404245545	0.874517369791212	cAMP signaling pathway: CREB3 CREBBP
hsa04064__142	0.857796184646864	DOWN	-0.179648066092935	0.884631740368528	NF-kappa B signaling pathway: NFKB2*
hsa04550__62 63	0.865148895906905	DOWN	-0.170291395983928	0.891725055079032	Signaling pathways regulating pluripotency of stem cells: SMAD2 SMAD4
hsa05221__27	0.865884820446724	UP	0.169355728973027	0.891994285975545	Acute myeloid leukemia: PIM2
hsa04210__10	0.87103951360027	DOWN	-0.162806059896722	0.896812737564333	Apoptosis: BIRC2
hsa04668__153	0.872513299702372	DOWN	-0.160934725874921	0.897838165465913	TNF signaling pathway: MAPK14*
hsa04151__24	0.873250359052276	DOWN	-0.15999905886402	0.898104775401875	PI3K-Akt signaling pathway: MYC
hsa04360__35	0.873987528429835	DOWN	-0.159063391853119	0.89837120673942	Axon guidance: ROCK1*
hsa05152__112	0.876199690436597	UP	0.156256390820417	0.900152661744322	Tuberculosis: IFNGR1
hsa04724__3	0.901334373515399	UP	0.124443712449793	0.925468463298052	Glutamatergic synapse: GRIK1
hsa04724__36	0.902816222488142	DOWN	-0.122572378427992	0.926483714940043	Glutamatergic synapse: TRPC1
hsa04024__116	0.903557274283581	UP	0.121636711417091	0.926738055883651	cAMP signaling pathway: ACOX1
hsa04360__101 103	0.914682775233499	UP	0.107601706253581	0.937637171120428	Axon guidance: DPYSL2 DPYSL5
hsa05212__54	0.91690995372117	UP	0.104794705220879	0.939407744297752	Pancreatic cancer: C00416
hsa05231__34	0.924338495587295	UP	0.0954380351118717	0.946502470413366	Choline metabolism in cancer: PLD1
hsa05145__67	0.925825017066785	DOWN	-0.0935667010900703	0.947508282717042	Toxoplasmosis: BAD
hsa04917__57	0.926568375255194	DOWN	-0.0926310340791696	0.947752845457	Prolactin signaling pathway: ESR1
hsa05160__85	0.929542442609855	UP	0.0888883660355668	0.950277611351424	Hepatitis C: BAD
hsa04917__47	0.93028611487067	DOWN	-0.087952699024666	0.950520723133218	Prolactin signaling pathway: INS
hsa04370__37	0.937726079044101	DOWN	-0.078596028915659	0.957601794849926	VEGF signaling pathway: CASP9
hsa04360__59	0.942192710549257	UP	0.0729820268502548	0.961640468833272	Axon guidance: MAPK1*
hsa04917__33	0.94368199879238	UP	0.0711106928284534	0.96263760897442	Prolactin signaling pathway: CSN2
hsa04727__17 37	0.948151024105965	DOWN	-0.0654966907630492	0.966671608407547	GABAergic synapse: GABRA1 GPHN
hsa05161__69	0.950386157460299	DOWN	-0.0626896897303471	0.968424940275435	Hepatitis B: SMAD4
hsa04724__51	0.954112238640815	DOWN	-0.0580113546758436	0.97169479480005	Glutamatergic synapse: ADRBK1
hsa04151__98	0.95485757786523	UP	0.0570756876649429	0.971927079528043	PI3K-Akt signaling pathway: BCL2L1*
hsa04071__57	0.957093829808899	UP	0.0542686866322408	0.97314897522236	Sphingolipid signaling pathway: BAX
hsa05200__52	0.957093829808899	DOWN	-0.0542686866322408	0.97314897522236	Pathways in cancer: CDKN1B
hsa03320__58	0.959330419494494	UP	0.0514616855995386	0.974895542579856	PPAR signaling pathway: CYP8B1
hsa04014__103	0.968279804060563	DOWN	-0.0402336814687302	0.983153047774488	Ras signaling pathway: KSR2
hsa05164__99	0.969025782053407	UP	0.0392980144578295	0.983153047774488	Influenza A: FDPS
hsa05211__3	0.969025782053407	UP	0.0392980144578295	0.983153047774488	Renal cell carcinoma: VEGFA
hsa05160__54	0.970517818697305	UP	0.0374266804360281	0.983604628550289	Hepatitis C: IRF1
hsa05166__83	0.970517818697305	UP	0.0374266804360281	0.983604628550289	HTLV-I infection: NFKB2
hsa05215__9	0.973502196355463	DOWN	-0.0336840123924253	0.9860973730199	Prostate cancer: CDKN1B
hsa04742__18	0.975740725372691	UP	0.0308770113597232	0.987832339965132	Taste transduction: PDE1A
hsa05164__78	0.979472022999687	DOWN	-0.0261986763052197	0.991075891877444	Influenza A: GSK3B
hsa05150__40	0.99066828447649	UP	0.0121636711417091	1	Staphylococcus aureus infection: FCGR1A
hsa04152__33	1	0	0	1	AMPK signaling pathway: CPT1C
hsa04152__41	1	0	0	1	AMPK signaling pathway: FBP1
hsa04211__2	1	0	0	1	Longevity regulating pathway - mammal: RPS6KB1
hsa04911__41	1	0	0	1	Insulin secretion: ABCC8
hsa04911__35	1	0	0	1	Insulin secretion: TRPM4
hsa04922__67	1	0	0	1	Glucagon signaling pathway: FBP1
hsa04922__60	1	0	0	1	Glucagon signaling pathway: CPT1C*
hsa04924__34	1	0	0	1	Renin secretion: REN
hsa04924__47	1	0	0	1	Renin secretion: KCNMA1
hsa04931__151	1	0	0	1	Insulin resistance: CPT1A
hsa04931__29	1	0	0	1	Insulin resistance: CPT1B
hsa04960__15	1	0	0	1	Aldosterone-regulated sodium reabsorption: C00762
hsa05030__13	1	0	0	1	Cocaine addiction: SLC6A3
hsa05031__15	1	0	0	1	Amphetamine addiction: MAOA
hsa05031__77	1	0	0	1	Amphetamine addiction: MAOA*
hsa05034__7	1	0	0	1	Alcoholism: GRIN3A
hsa05034__75	1	0	0	1	Alcoholism: SLC29A1
hsa05140__37	1	0	0	1	Leishmaniasis: ELK1
hsa05140__55	1	0	0	1	Leishmaniasis: JUN
hsa05140__41 57	1	0	0	1	Leishmaniasis: NOS2 CYBA
hsa05211__12	1	0	0	1	Renal cell carcinoma: EGLN2