p.value	UP.DOWN	statistic	FDRp.value	path.name
hsa05169__11	2.62934594384312e-30	DOWN	-11.040775977132	4.94054102848122e-27	Epstein-Barr virus infection: HLA-A
hsa04211__43 59 60 61	2.44129477471974e-28	UP	11.040775977132	1.99661514483635e-26	Longevity regulating pathway - mammal: ULK3 RB1CC1 ATG13 ATG101
hsa04750__8	2.44129477471974e-28	DOWN	-11.040775977132	1.99661514483635e-26	Inflammatory mediator regulation of TRP channels: ASIC2
hsa04530__11 24 23	2.4448094040992e-28	DOWN	-11.040775977132	1.99661514483635e-26	Tight junction: TJP1 YBX3 CDK4
hsa04261__73	2.50799622719409e-28	DOWN	-11.0384829810828	1.99661514483635e-26	Adrenergic signaling in cardiomyocytes: KCNE1
hsa04916__9	2.50799622719409e-28	DOWN	-11.0384829810828	1.99661514483635e-26	Melanogenesis: PRKACA
hsa04925__18	2.5401944625604e-28	DOWN	-11.0373364830581	1.99661514483635e-26	Aldosterone synthesis and secretion: PDE2A
hsa04670__15	2.57266839876061e-28	DOWN	-11.0361899850335	1.99661514483635e-26	Leukocyte transendothelial migration: PECAM1
hsa04261__39	2.57280271095543e-28	DOWN	-11.0361899850335	1.99661514483635e-26	Adrenergic signaling in cardiomyocytes: SCN1B
hsa04970__18	2.57280271095543e-28	DOWN	-11.0361899850335	1.99661514483635e-26	Salivary secretion: VAMP2
hsa04261__66	2.60582615008602e-28	DOWN	-11.0350434870089	1.99661514483635e-26	Adrenergic signaling in cardiomyocytes: C01245
hsa04213__62	2.67313963632441e-28	DOWN	-11.0327504909596	1.99661514483635e-26	Longevity regulating pathway - multiple species: CAT*
hsa03320__38	2.70744036621265e-28	DOWN	-11.031603992935	1.99661514483635e-26	PPAR signaling pathway: SORBS1
hsa04115__11 12	2.70744036621265e-28	UP	11.031603992935	1.99661514483635e-26	p53 signaling pathway: CDK2 CCNE1
hsa04916__10	2.70744036621265e-28	DOWN	-11.031603992935	1.99661514483635e-26	Melanogenesis: CAMK2A
hsa04933__62	2.70744036621265e-28	DOWN	-11.031603992935	1.99661514483635e-26	AGE-RAGE signaling pathway in diabetic complications: AGER**
hsa04066__56	2.77735700978602e-28	DOWN	-11.0293109968858	1.99661514483635e-26	HIF-1 signaling pathway: TEK
hsa04261__72	2.77735700978602e-28	DOWN	-11.0293109968858	1.99661514483635e-26	Adrenergic signaling in cardiomyocytes: ATP2B1
hsa04670__18	2.81291557997415e-28	DOWN	-11.0281644988611	1.99661514483635e-26	Leukocyte transendothelial migration: CDH5
hsa04261__4	2.88560362390302e-28	DOWN	-11.0258715028119	1.99661514483635e-26	Adrenergic signaling in cardiomyocytes: SLC8A1
hsa04152__78	2.92260774317251e-28	UP	11.0247250047873	1.99661514483635e-26	AMPK signaling pathway: CCNA2
hsa05166__64	3.07539065380914e-28	UP	11.0201390126888	1.99661514483635e-26	HTLV-I infection: CCNB2
hsa04110__59 15 16 17 18 19 20	3.11480823451589e-28	UP	11.0189925146641	1.99661514483635e-26	Cell cycle: CDC45 MCM7 MCM6 MCM5 MCM4 MCM3 MCM2
hsa04261__52	3.15472692000015e-28	DOWN	-11.0178460166395	1.99661514483635e-26	Adrenergic signaling in cardiomyocytes: MAPK14
hsa05200__205	3.15472692000015e-28	UP	11.0178460166395	1.99661514483635e-26	Pathways in cancer: SLC2A1
hsa05211__4	3.2360929533311e-28	UP	11.0155530205903	1.99661514483635e-26	Renal cell carcinoma: SLC2A1
hsa05200__168	3.27755317356782e-28	UP	11.0144065225656	1.99661514483635e-26	Pathways in cancer: E2F1
hsa04261__36	3.36206080764059e-28	DOWN	-11.0121135265164	1.99661514483635e-26	Adrenergic signaling in cardiomyocytes: MAPK1
hsa04933__29	3.44872937573245e-28	DOWN	-11.0098205304671	1.99661514483635e-26	AGE-RAGE signaling pathway in diabetic complications: ICAM1
hsa04014__67	3.49289107839907e-28	DOWN	-11.0086740324425	1.99661514483635e-26	Ras signaling pathway: RAPGEF5*
hsa05211__42	3.49289107839907e-28	UP	11.0086740324425	1.99661514483635e-26	Renal cell carcinoma: SLC2A1*
hsa04022__39	3.67521783669326e-28	DOWN	-11.004088040344	1.99661514483635e-26	cGMP-PKG signaling pathway: KCNJ8
hsa04933__35	3.76989026421471e-28	DOWN	-11.0017950442948	1.99661514483635e-26	AGE-RAGE signaling pathway in diabetic complications: CCND1
hsa04914__30	3.81801081187589e-28	UP	11.0006485462702	1.99661514483635e-26	Progesterone-mediated oocyte maturation: CDK1*
hsa04114__80	3.91645278932854e-28	UP	10.9983555502209	1.99661514483635e-26	Oocyte meiosis: CDC25C*
hsa04530__11 62	3.96655206005388e-28	DOWN	-10.9972090521963	1.99661514483635e-26	Tight junction: TJP1 SHROOM1
hsa04115__43 57	4.17338592320215e-28	UP	10.9926230600978	1.99661514483635e-26	p53 signaling pathway: CDK1 CCNB3
hsa04022__57	4.28077934801934e-28	DOWN	-10.9903300640485	1.99661514483635e-26	cGMP-PKG signaling pathway: C00144
hsa04933__22	4.33549950745149e-28	DOWN	-10.9891835660239	1.99661514483635e-26	AGE-RAGE signaling pathway in diabetic complications: EDN1
hsa04621__33 35	4.61968260190256e-28	DOWN	-10.9834510759008	1.99661514483635e-26	NOD-like receptor signaling pathway: NLRC4 PYCARD
hsa05169__45	4.73846167552574e-28	DOWN	-10.9811580798515	1.99661514483635e-26	Epstein-Barr virus infection: RB1
hsa04933__24	4.92233283589114e-28	DOWN	-10.9777185857777	1.99661514483635e-26	AGE-RAGE signaling pathway in diabetic complications: THBD
hsa03460__25 40	5.17854616965297e-28	UP	10.9731325936792	1.99661514483635e-26	Fanconi anemia pathway: MLH1 PMS2
hsa04925__3	5.24463967245017e-28	DOWN	-10.9719860956545	1.99661514483635e-26	Aldosterone synthesis and secretion: ITPR1
hsa04924__23	5.31156979648206e-28	DOWN	-10.9708395976299	1.99661514483635e-26	Renin secretion: ITPR1
hsa05210__21	5.37934704273223e-28	UP	10.9696930996053	1.99661514483635e-26	Colorectal cancer: BIRC5
hsa04933__57	5.44798204285228e-28	DOWN	-10.9685466015807	1.99661514483635e-26	AGE-RAGE signaling pathway in diabetic complications: FIGF
hsa04110__60 10 11 12 13 14 9	5.51748556077329e-28	DOWN	-10.9674001035561	1.99661514483635e-26	Cell cycle: CDC6 ORC3 ORC5 ORC4 ORC2 ORC1 ORC6
hsa04910__46	5.58786849433706e-28	DOWN	-10.9662536055314	1.99661514483635e-26	Insulin signaling pathway: FBP1
hsa03320__30	5.65914187694731e-28	DOWN	-10.9651071075068	1.99661514483635e-26	PPAR signaling pathway: LPL
hsa04520__1 13	5.73131687924104e-28	DOWN	-10.9639606094822	1.99661514483635e-26	Adherens junction: SMAD4 SMAD2
hsa03320__31	5.80440481078021e-28	DOWN	-10.9628141114576	1.99661514483635e-26	PPAR signaling pathway: CD36
hsa04914__11	5.80440481078021e-28	UP	10.9628141114576	1.99661514483635e-26	Progesterone-mediated oocyte maturation: CDK1
hsa04933__19	5.87841712176466e-28	DOWN	-10.9616676134329	1.99661514483635e-26	AGE-RAGE signaling pathway in diabetic complications: TGFBR2
hsa04012__8	5.95336540476476e-28	DOWN	-10.9605211154083	1.99661514483635e-26	ErbB signaling pathway: STAT5A
hsa04920__31	6.10611697949699e-28	DOWN	-10.9582281193591	1.99661514483635e-26	Adipocytokine signaling pathway: AGRP
hsa04261__23	6.1839441841228e-28	DOWN	-10.9570816213344	1.99661514483635e-26	Adrenergic signaling in cardiomyocytes: SLC9A1
hsa03460__7	6.42337808444803e-28	UP	10.9536421272606	1.99661514483635e-26	Fanconi anemia pathway: FANCI
hsa05200__189	6.50521509659342e-28	UP	10.9524956292359	1.99661514483635e-26	Pathways in cancer: BIRC5
hsa03460__28	6.58808616178041e-28	UP	10.9513491312113	1.99661514483635e-26	Fanconi anemia pathway: RAD51C
hsa04014__76	6.58808616178041e-28	DOWN	-10.9513491312113	1.99661514483635e-26	Ras signaling pathway: RALBP1*
hsa04540__14 31	6.58808616178041e-28	DOWN	-10.9513491312113	1.99661514483635e-26	Gap junction: GJA1 TJP1
hsa04022__65	6.75698243414746e-28	DOWN	-10.9490561351621	2.01529682440684e-26	cGMP-PKG signaling pathway: PDE2A
hsa04211__56	7.1982458908931e-28	DOWN	-10.9433236450389	2.06192699311253e-26	Longevity regulating pathway - mammal: CAT
hsa04261__3	7.1982458908931e-28	DOWN	-10.9433236450389	2.06192699311253e-26	Adrenergic signaling in cardiomyocytes: RYR2
hsa03320__60	7.28986954729601e-28	DOWN	-10.9421771470143	2.06192699311253e-26	PPAR signaling pathway: CYP27A1
hsa03320__23	7.38264981845233e-28	DOWN	-10.9410306489897	2.06192699311253e-26	PPAR signaling pathway: ACADL
hsa04115__38	7.57173829296247e-28	UP	10.9387376529404	2.06192699311253e-26	p53 signaling pathway: GTSE1
hsa04213__60	7.57173829296247e-28	DOWN	-10.9387376529404	2.06192699311253e-26	Longevity regulating pathway - multiple species: CAT
hsa04933__12	7.76562929992493e-28	DOWN	-10.9364446568912	2.08451677922271e-26	AGE-RAGE signaling pathway in diabetic complications: EGR1
hsa04530__20 22	7.9644437703333e-28	DOWN	-10.9341516608419	2.10777321752905e-26	Tight junction: ACTB MYL12B
hsa05166__65	8.16830565354488e-28	UP	10.9318586647927	2.12923362497283e-26	HTLV-I infection: PTTG2
hsa04933__56	8.27216895279491e-28	DOWN	-10.9307121667681	2.12923362497283e-26	AGE-RAGE signaling pathway in diabetic complications: NFATC1
hsa05133__46	8.48384114710083e-28	DOWN	-10.9284191707188	2.15250298028032e-26	Pertussis: CFL1
hsa04330__11	8.59168299739352e-28	DOWN	-10.9272726726942	2.15250298028032e-26	Notch signaling pathway: PTCRA
hsa03320__29	8.81146212966621e-28	DOWN	-10.924979676645	2.17694584563242e-26	PPAR signaling pathway: OLR1
hsa04014__66	8.92343360733606e-28	DOWN	-10.9238331786203	2.17694584563242e-26	Ras signaling pathway: RAF1*
hsa04261__34	9.036816176654e-28	DOWN	-10.9226866805957	2.17694584563242e-26	Adrenergic signaling in cardiomyocytes: AKT3
hsa04530__11 36 14	9.99683841741163e-28	DOWN	-10.9135146963987	2.34800742328956e-26	Tight junction: TJP1 CTNNB1 CTNNA1
hsa04923__66	9.99683841741163e-28	DOWN	-10.9135146963987	2.34800742328956e-26	Regulation of lipolysis in adipocytes: LIPE
hsa04976__16	1.01237410310061e-27	DOWN	-10.9123681983741	2.34845795027907e-26	Bile secretion: CFTR
hsa03460__27	1.038235890387e-27	UP	10.9100752023248	2.35041594944237e-26	Fanconi anemia pathway: BRCA1
hsa04014__69	1.038235890387e-27	DOWN	-10.9100752023248	2.35041594944237e-26	Ras signaling pathway: PLCE1*
hsa04211__29	1.09194122695402e-27	DOWN	-10.9054892102263	2.41383242993717e-26	Longevity regulating pathway - mammal: EIF4E
hsa04933__65	1.09194122695402e-27	DOWN	-10.9054892102263	2.41383242993717e-26	AGE-RAGE signaling pathway in diabetic complications: COL1A1
hsa04068__59	1.10579253571429e-27	DOWN	-10.9043427122017	2.41602811000832e-26	FoxO signaling pathway: S1PR1
hsa04530__11 13	1.13402005887584e-27	DOWN	-10.9020497161525	2.44922263290541e-26	Tight junction: TJP1 EPB41
hsa04933__78	1.19263652629517e-27	DOWN	-10.897463724054	2.54655003739617e-26	AGE-RAGE signaling pathway in diabetic complications: TGFB1
hsa05010__59	1.20774593754833e-27	DOWN	-10.8963172260293	2.54983664792507e-26	Alzheimer's disease: LRP1
hsa03460__48	1.2230617752578e-27	UP	10.8951707280047	2.55348119523268e-26	Fanconi anemia pathway: RAD51
hsa04530__6 11 45	1.23856181738884e-27	DOWN	-10.8940242299801	2.55742599436664e-26	Tight junction: CLDN24 TJP1 TJP2
hsa05161__213	1.31903300868255e-27	UP	10.888291739857	2.69398154708098e-26	Hepatitis B: E2F1
hsa04012__22	1.40468674235718e-27	UP	10.8825592497339	2.80787913711612e-26	ErbB signaling pathway: EIF4EBP1
hsa04213__54	1.40468674235718e-27	DOWN	-10.8825592497339	2.80787913711612e-26	Longevity regulating pathway - multiple species: SOD2*
hsa04972__42	1.4224681420911e-27	DOWN	-10.8814127517092	2.81349225156755e-26	Pancreatic secretion: CFTR
hsa04261__20	1.45870334902734e-27	DOWN	-10.87911975566	2.85510790918997e-26	Adrenergic signaling in cardiomyocytes: ATP1B4
hsa04014__62	1.49585379095013e-27	DOWN	-10.8768267596107	2.89763842597454e-26	Ras signaling pathway: RASSF5
hsa03320__40	1.51477936450798e-27	DOWN	-10.8756802615861	2.90435757745968e-26	PPAR signaling pathway: FABP4
hsa04530__11 33	1.55334580527547e-27	DOWN	-10.8733872655369	2.94821895768951e-26	Tight junction: TJP1 CGN
hsa03320__7	1.71759423467943e-27	DOWN	-10.8642152813399	3.22735956696265e-26	PPAR signaling pathway: AQP7
hsa04668__120	1.73930032695878e-27	UP	10.8630687833152	3.235787439956e-26	TNF signaling pathway: DNM1L
hsa04022__46	1.85197922027946e-27	DOWN	-10.8573362931921	3.41163623029913e-26	cGMP-PKG signaling pathway: VASP
hsa05221__35	1.8753689312682e-27	UP	10.8561897951675	3.42118273966306e-26	Acute myeloid leukemia: EIF4EBP1
hsa04540__14 16	1.94731021339657e-27	DOWN	-10.8527503010936	3.48475799140205e-26	Gap junction: GJA1 GJA1
hsa04540__14 15	1.94731021339657e-27	DOWN	-10.8527503010936	3.48475799140205e-26	Gap junction: GJA1 GJA1*
hsa04152__62	2.12599210607283e-27	UP	10.8447248149212	3.76862185595362e-26	AMPK signaling pathway: EIF4EBP1
hsa04960__3	2.17996659597775e-27	DOWN	-10.842431818872	3.82818433069363e-26	Aldosterone-regulated sodium reabsorption: SCNN1A
hsa04010__13	2.20746123213877e-27	UP	10.8412853208474	3.8405737548044e-26	MAPK signaling pathway: STMN1
hsa04066__55	2.23529972756959e-27	DOWN	-10.8401388228228	3.85332861293877e-26	HIF-1 signaling pathway: ANGPT1
hsa04110__43 83 84 85	2.26348634566604e-27	DOWN	-10.8389923247981	3.86644622136953e-26	Cell cycle: SMC1B SMC3 STAG1 RAD21
hsa04151__2	2.32092126604322e-27	DOWN	-10.8366993287489	3.92883879179749e-26	PI3K-Akt signaling pathway: EIF4E
hsa04664__23	2.37980115983949e-27	DOWN	-10.8344063326996	3.99254141012358e-26	Fc epsilon RI signaling pathway: AKT3
hsa04933__30	2.40979419845694e-27	DOWN	-10.833259834675	4.00708256539875e-26	AGE-RAGE signaling pathway in diabetic complications: CXCL8
hsa04933__23	2.59778831822064e-27	DOWN	-10.8263808465273	4.28179320169875e-26	AGE-RAGE signaling pathway in diabetic complications: F3
hsa05110__17	2.76550655727732e-27	DOWN	-10.8206483564041	4.51859723576007e-26	Vibrio cholerae infection: C00698*
hsa04530__20 62	2.87124636074033e-27	DOWN	-10.8172088623303	4.65092406192335e-26	Tight junction: ACTB SHROOM1
hsa04933__52	2.94395705280642e-27	DOWN	-10.814915866281	4.72794470275492e-26	AGE-RAGE signaling pathway in diabetic complications: FOXO1
hsa04924__31	3.05629678766452e-27	DOWN	-10.8114763722071	4.8261249391476e-26	Renin secretion: C02135
hsa04152__61	3.0564601796624e-27	UP	10.8114763722071	4.8261249391476e-26	AMPK signaling pathway: RPS6KB1
hsa04916__15	3.13382032048035e-27	DOWN	-10.8091833761579	4.90704031848548e-26	Melanogenesis: MITF*
hsa04923__16	3.17322537210864e-27	DOWN	-10.8080368781333	4.92767807784474e-26	Regulation of lipolysis in adipocytes: PLIN1
hsa05145__29	3.25348285507895e-27	DOWN	-10.805743882084	4.97020772187466e-26	Toxoplasmosis: C06314
hsa04022__71	3.25351543262684e-27	UP	10.805743882084	4.97020772187466e-26	cGMP-PKG signaling pathway: PPIF
hsa04666__41	3.59532400833644e-27	UP	10.796571897887	5.44807565456788e-26	Fc gamma R-mediated phagocytosis: MARCKS
hsa05169__30	3.82679643448859e-27	DOWN	-10.7908394077639	5.75244040032325e-26	Epstein-Barr virus infection: FGR
hsa04810__35 81 80	3.8748342265919e-27	DOWN	-10.7896929097393	5.77842342203666e-26	Regulation of actin cytoskeleton: MYL12B MYH9 ACTB
hsa04380__68	3.92346992223835e-27	DOWN	-10.7885464117147	5.80488187707547e-26	Osteoclast differentiation: TGFBR1
hsa04920__43	4.22825956403519e-27	DOWN	-10.7816674235669	6.20695290689228e-26	Adipocytokine signaling pathway: C00162
hsa04066__11	4.33498448838303e-27	UP	10.7793744275177	6.21788996463489e-26	HIF-1 signaling pathway: SLC2A1
hsa05014__49	4.33498448838303e-27	DOWN	-10.7793744275177	6.21788996463489e-26	Amyotrophic lateral sclerosis (ALS): C00001
hsa05200__214	4.33498448838303e-27	DOWN	-10.7793744275177	6.21788996463489e-26	Pathways in cancer: CSF3R
hsa04014__68	4.38934434307716e-27	DOWN	-10.778227929493	6.24816516715302e-26	Ras signaling pathway: RALGDS*
hsa04933__61	4.44438006559372e-27	DOWN	-10.7770814314684	6.27893995733127e-26	AGE-RAGE signaling pathway in diabetic complications: MMP2
hsa04213__71	4.55651253571796e-27	DOWN	-10.7747884354192	6.38931869747317e-26	Longevity regulating pathway - multiple species: SIRT1**
hsa04922__17	4.72999183155304e-27	DOWN	-10.7713489413453	6.58344788999123e-26	Glucagon signaling pathway: PKM
hsa04340__15	5.03379396818464e-27	DOWN	-10.7656164512222	6.95477857810216e-26	Hedgehog signaling pathway: HHIP
hsa04510__19 23	5.70063275235505e-27	DOWN	-10.7541514709759	7.81860506691616e-26	Focal adhesion: VCL TLN1
hsa04068__58	6.21883044729238e-27	DOWN	-10.7461259848036	8.46752348584231e-26	FoxO signaling pathway: KLF2
hsa04068__52	6.53563909750374e-27	DOWN	-10.7415399927051	8.81838692932665e-26	FoxO signaling pathway: CAT
hsa05110__51	6.61717910971279e-27	UP	10.7403934946804	8.81838692932665e-26	Vibrio cholerae infection: PDIA4
hsa04270__10 3 71	6.61731004276242e-27	DOWN	-10.7403934946804	8.81838692932665e-26	Vascular smooth muscle contraction: ACTA2 MYL9 MYH11
hsa04270__17	6.69999283391775e-27	DOWN	-10.7392469966558	8.86569474290947e-26	Vascular smooth muscle contraction: ITPR1
hsa04066__44	6.78369989700331e-27	DOWN	-10.7381004986312	8.91368678774072e-26	HIF-1 signaling pathway: GAPDH
hsa04022__48	6.86844380927663e-27	DOWN	-10.7369540006066	8.96236522057693e-26	cGMP-PKG signaling pathway: SLC8A2
hsa05166__136 139	7.04109325749814e-27	UP	10.7346610045573	9.12428567644069e-26	HTLV-I infection: TP53 TBPL2
hsa04152__87	7.21804489095472e-27	DOWN	-10.7323680085081	9.28952489733146e-26	AMPK signaling pathway: CD36
hsa04066__45	7.30816712972847e-27	DOWN	-10.7312215104834	9.34152791616313e-26	HIF-1 signaling pathway: ALDOA
hsa04666__20	7.39940496058415e-27	DOWN	-10.7300750124588	9.39424454117406e-26	Fc gamma R-mediated phagocytosis: PLA2G4B
hsa04924__30	7.58528231744253e-27	UP	10.7277820164096	9.5656009895802e-26	Renin secretion: PDE3A
hsa04010__67	8.27306148221052e-27	UP	10.7197565302372	1.0363388350049e-25	MAPK signaling pathway: ELK1
hsa04650__110 111	9.13506653801073e-27	DOWN	-10.7105845460402	1.13674106125312e-25	Natural killer cell mediated cytotoxicity: ITGAL ITGB2
hsa04014__65	9.36412968162576e-27	DOWN	-10.708291549991	1.15757892577466e-25	Ras signaling pathway: MLLT4*
hsa04530__13 45 20	9.718443861404e-27	DOWN	-10.7048520559171	1.19352653696589e-25	Tight junction: EPB41 TJP2 ACTB
hsa04510__19 26	1.07295946802046e-26	DOWN	-10.6956800717201	1.30914989637041e-25	Focal adhesion: VCL ACTN4
hsa04022__66	1.14138335264225e-26	UP	10.689947581597	1.38365117394502e-25	cGMP-PKG signaling pathway: PDE3A
hsa05205__324	1.19922291361759e-26	DOWN	-10.6853615894985	1.44444862479965e-25	Proteoglycans in cancer: KDR*
hsa04115__24	1.24450103438799e-26	UP	10.6819220954246	1.48943786217518e-25	p53 signaling pathway: SERPINB5
hsa04066__58	1.30751835736668e-26	DOWN	-10.6773361033261	1.55495379334936e-25	HIF-1 signaling pathway: EDN1
hsa04530__5 10	1.35684816231324e-26	DOWN	-10.6738966092522	1.59344856061662e-25	Tight junction: IGSF5 MAGI1
hsa04664__30	1.35684816231324e-26	DOWN	-10.6738966092522	1.59344856061662e-25	Fc epsilon RI signaling pathway: PRKCA
hsa04914__34	1.37369801444228e-26	DOWN	-10.6727501112276	1.60321650256959e-25	Progesterone-mediated oocyte maturation: MAPK14
hsa04530__22 33	1.49759905719427e-26	DOWN	-10.6647246250552	1.73703001757286e-25	Tight junction: MYL12B CGN
hsa04390__13	1.51618099648343e-26	UP	10.6635781270306	1.7477939217131e-25	Hippo signaling pathway: BIRC5
hsa04110__10 11 12 13 14 9 15 16 17 18 19 20	1.53499149631702e-26	UP	10.662431629006	1.75868842779248e-25	Cell cycle: ORC3 ORC5 ORC4 ORC2 ORC1 ORC6 MCM7 MCM6 MCM5 MCM4 MCM3 MCM2
hsa03320__28	1.57330935646604e-26	DOWN	-10.6601386329567	1.79166562472708e-25	PPAR signaling pathway: ACSL1
hsa04530__11 43	1.61257533432184e-26	DOWN	-10.6578456369075	1.82531870674141e-25	Tight junction: TJP1 ACTN4
hsa04360__108	1.69404520065819e-26	DOWN	-10.653259644809	1.9060544503214e-25	Axon guidance: CFL1
hsa04660__35	1.93973316616612e-26	DOWN	-10.6406481665381	2.16949917811079e-25	T cell receptor signaling pathway: NFATC1
hsa04062__44	1.98805608537138e-26	DOWN	-10.6383551704889	2.21038898485966e-25	Chemokine signaling pathway: MAPK1
hsa04611__7	2.03757220903178e-26	DOWN	-10.6360621744396	2.25211657692395e-25	Platelet activation: ITPR1
hsa04530__5 15	2.06278681889518e-26	DOWN	-10.634915676415	2.26665288462225e-25	Tight junction: IGSF5 MPDZ
hsa05218__8	2.16677613362856e-26	UP	10.6303296843165	2.36707695063259e-25	Melanoma: CDK4
hsa04960__13	2.24816339081441e-26	DOWN	-10.6268901902426	2.44179133603484e-25	Aldosterone-regulated sodium reabsorption: FXYD4
hsa04921__46	2.27596029872301e-26	DOWN	-10.625743692218	2.44373108645745e-25	Oxytocin signaling pathway: C00942*
hsa04972__39	2.27596029872301e-26	DOWN	-10.625743692218	2.44373108645745e-25	Pancreatic secretion: KCNMA1*
hsa04270__48	2.30409789207096e-26	DOWN	-10.6245971941934	2.44598866621544e-25	Vascular smooth muscle contraction: KCNMB2*
hsa04930__15	2.30409789207096e-26	DOWN	-10.6245971941934	2.44598866621544e-25	Type II diabetes mellitus: C00031*
hsa03460__16 49	2.90925656949484e-26	UP	10.6028137317255	3.05390675646972e-25	Fanconi anemia pathway: FANCM C19orf40
hsa04728__64	2.90925656949484e-26	DOWN	-10.6028137317255	3.05390675646972e-25	Dopaminergic synapse: SCN1A
hsa04961__5	2.98147591196755e-26	DOWN	-10.6005207356763	3.1123295769928e-25	Endocrine and other factor-regulated calcium reabsorption: TRPV5
hsa04014__26	3.28856014101033e-26	DOWN	-10.5913487514793	3.413925140861e-25	Ras signaling pathway: PRKCA
hsa05130__28	3.67162891871066e-26	DOWN	-10.5810302692577	3.79065425178974e-25	Pathogenic Escherichia coli infection: ROCK1
hsa04014__64	3.85577836635168e-26	DOWN	-10.5764442771592	3.9162202974999e-25	Ras signaling pathway: PIK3R5*
hsa04670__73	3.85577836635168e-26	DOWN	-10.5764442771592	3.9162202974999e-25	Leukocyte transendothelial migration: MYL12B*
hsa04931__61	3.85577836635168e-26	DOWN	-10.5764442771592	3.9162202974999e-25	Insulin resistance: ACACB
hsa04962__22	4.09888682995918e-26	DOWN	-10.570711787036	4.14075717929748e-25	Vasopressin-regulated water reabsorption: ARHGDIA
hsa04611__34	4.51983602977473e-26	DOWN	-10.561539802839	4.54158925130841e-25	Platelet activation: C02198*
hsa04068__39	4.63160173366532e-26	UP	10.5592468067898	4.62913811572188e-25	FoxO signaling pathway: CCNB3
hsa04530__5 11 31	4.80440659961053e-26	DOWN	-10.5558073127159	4.75130526350958e-25	Tight junction: IGSF5 TJP1 MLLT4
hsa04921__58	4.80440659961053e-26	DOWN	-10.5558073127159	4.75130526350958e-25	Oxytocin signaling pathway: MEF2C
hsa05205__158	5.29709355468535e-26	DOWN	-10.5466353285189	5.21111978494962e-25	Proteoglycans in cancer: PDCD4
hsa03460__16 34	6.51647726857052e-26	UP	10.5271448621003	6.37732332689792e-25	Fanconi anemia pathway: FANCM STRA13
hsa04933__58	6.67709343686937e-26	DOWN	-10.5248518660511	6.50065210770857e-25	AGE-RAGE signaling pathway in diabetic complications: CCL2
hsa04914__39	6.75886682317206e-26	DOWN	-10.5237053680264	6.52559794746003e-25	Progesterone-mediated oocyte maturation: PIK3R5
hsa04723__40	6.84163276024282e-26	DOWN	-10.5225588700018	6.52559794746003e-25	Retrograde endocannabinoid signaling: GRIA1
hsa04724__4	6.84163276024282e-26	DOWN	-10.5225588700018	6.52559794746003e-25	Glutamatergic synapse: GRIA1
hsa05031__12	6.84163276024282e-26	DOWN	-10.5225588700018	6.52559794746003e-25	Amphetamine addiction: GRIA1
hsa04664__47	6.92540318537297e-26	DOWN	-10.5214123719772	6.57213766935142e-25	Fc epsilon RI signaling pathway: MAPK8
hsa04914__15	7.27077352539342e-26	UP	10.5168263798787	6.86521781618805e-25	Progesterone-mediated oocyte maturation: ANAPC10
hsa04664__3 4 5	7.35963411739488e-26	DOWN	-10.5156798818541	6.91437625329249e-25	Fc epsilon RI signaling pathway: FCER1G MS4A2 FCER1A
hsa04540__22	7.54066881593783e-26	DOWN	-10.5133868858048	7.01458127134825e-25	Gap junction: C00547
hsa05031__55	7.54095485264687e-26	DOWN	-10.5133868858048	7.01458127134825e-25	Amphetamine addiction: GRIA1*
hsa04114__56	8.61953323216223e-26	DOWN	-10.500775407534	7.97837583410484e-25	Oocyte meiosis: REC8
hsa04972__21	8.83145546785822e-26	DOWN	-10.4984824114847	8.13446314907137e-25	Pancreatic secretion: KCNQ1
hsa05166__62 63	9.85082664926263e-26	UP	10.4881639292631	9.02912354827536e-25	HTLV-I infection: ANAPC10 CDC20
hsa04066__89	9.97105247225734e-26	DOWN	-10.4870174312385	9.09495514338425e-25	HIF-1 signaling pathway: CDKN1A
hsa04670__28 41 49	1.00927324565444e-25	DOWN	-10.4858709332138	9.16147066949127e-25	Leukocyte transendothelial migration: ACTB CTNNA1 CTNNB1
hsa04010__79	1.13934493646234e-25	UP	10.4744059529676	1.01944244552988e-24	MAPK signaling pathway: HSPB1
hsa04066__52	1.13934493646234e-25	DOWN	-10.4744059529676	1.01944244552988e-24	HIF-1 signaling pathway: FLT1
hsa04931__149	1.13934493646234e-25	DOWN	-10.4744059529676	1.01944244552988e-24	Insulin resistance: ACACB*
hsa04728__70 73	1.16728721433054e-25	DOWN	-10.4721129569184	1.03949415911236e-24	Dopaminergic synapse: KIF5A GRIA1
hsa05132__55	1.25525411162814e-25	DOWN	-10.4652339687706	1.11255777157985e-24	Salmonella infection: IL18
hsa04066__46	1.38283976646653e-25	DOWN	-10.4560619845736	1.21988540900967e-24	HIF-1 signaling pathway: ENO1
hsa04962__10	1.67781325716724e-25	DOWN	-10.4377180161796	1.47318276178376e-24	Vasopressin-regulated water reabsorption: AQP2
hsa05211__45	1.76081579887901e-25	DOWN	-10.4331320240811	1.538871109811e-24	Renal cell carcinoma: ETS1
hsa04010__64	1.84788600660927e-25	UP	10.4285460319826	1.6074897251939e-24	MAPK signaling pathway: DDIT3
hsa04920__28	1.8930078139816e-25	UP	10.4262530359334	1.63915284906517e-24	Adipocytokine signaling pathway: SLC2A1
hsa04152__89	2.29556059004822e-25	DOWN	-10.4079090675394	1.97860474711037e-24	AMPK signaling pathway: CFTR
hsa04014__58 59	2.43796048788176e-25	DOWN	-10.4021765774163	2.09174783412321e-24	Ras signaling pathway: STK4 STK4
hsa05166__60	2.5275666353652e-25	UP	10.3987370833424	2.15877168538692e-24	HTLV-I infection: POLD3
hsa04611__43	2.7166847087773e-25	DOWN	-10.3918580951947	2.2993921476543e-24	Platelet activation: MYL12B
hsa04740__21	2.7166847087773e-25	DOWN	-10.3918580951947	2.2993921476543e-24	Olfactory transduction: PDE1A
hsa04725__18	2.78278883952938e-25	DOWN	-10.3895650991454	2.3447803719622e-24	Cholinergic synapse: ITPR1
hsa04022__44	3.02695510842015e-25	DOWN	-10.381539612973	2.53912886103637e-24	cGMP-PKG signaling pathway: BAD
hsa04911__25	3.1379887021897e-25	DOWN	-10.3781001188992	2.62056923173976e-24	Insulin secretion: PRKCA
hsa05142__21	3.21424376501007e-25	DOWN	-10.3758071228499	2.67237346657253e-24	Chagas disease (American trypanosomiasis): TICAM1
hsa04970__27	3.3320822884014e-25	DOWN	-10.372367628776	2.75502683368659e-24	Salivary secretion: PRKCA
hsa04530__1 5	3.37230533128215e-25	DOWN	-10.3712211307514	2.75502683368659e-24	Tight junction: IGSF5 IGSF5
hsa04723__10	3.37230533128215e-25	UP	10.3712211307514	2.75502683368659e-24	Retrograde endocannabinoid signaling: CACNA1A
hsa04723__21	3.37230533128215e-25	UP	10.3712211307514	2.75502683368659e-24	Retrograde endocannabinoid signaling: CACNA1A*
hsa04933__25	3.84779942682771e-25	DOWN	-10.3586096524805	3.12987667662739e-24	AGE-RAGE signaling pathway in diabetic complications: IL1A
hsa04024__114	4.285795913269e-25	DOWN	-10.3482911702589	3.45622769143024e-24	cAMP signaling pathway: HHIP
hsa04911__4	4.285795913269e-25	DOWN	-10.3482911702589	3.45622769143024e-24	Insulin secretion: CACNA1C
hsa05215__39	4.33741298408138e-25	UP	10.3471446722343	3.4829055543115e-24	Prostate cancer: RB1
hsa04660__40 41	4.49598907025325e-25	DOWN	-10.3437051781604	3.59487806936419e-24	T cell receptor signaling pathway: LAT GRAP2
hsa04660__41 46	4.60488439929191e-25	DOWN	-10.3414121821112	3.66634651960572e-24	T cell receptor signaling pathway: GRAP2 LCP2
hsa05164__68	4.77314597856163e-25	UP	10.3379726880373	3.78427902688493e-24	Influenza A: EIF2S1
hsa04664__25	5.06722328496159e-25	DOWN	-10.3322401979142	4.00055149262304e-24	Fc epsilon RI signaling pathway: MAPK14
hsa04925__5	5.57551695070044e-25	DOWN	-10.3230682137172	4.38342943529964e-24	Aldosterone synthesis and secretion: KCNK3
hsa04022__50	5.64250537953742e-25	DOWN	-10.3219217156926	4.41761150339617e-24	cGMP-PKG signaling pathway: ATP2B1
hsa04152__64	5.71029121827022e-25	DOWN	-10.3207752176679	4.45213161789616e-24	AMPK signaling pathway: ACACB
hsa05211__40	6.28243629482054e-25	UP	10.311603233471	4.87797429668091e-24	Renal cell carcinoma: PAK4
hsa05110__14	6.74849154369023e-25	DOWN	-10.3047242453232	5.17567984105875e-24	Vibrio cholerae infection: C00238*
hsa05110__15	6.74849154369023e-25	DOWN	-10.3047242453232	5.17567984105875e-24	Vibrio cholerae infection: C01330
hsa05110__16	6.74849154369023e-25	DOWN	-10.3047242453232	5.17567984105875e-24	Vibrio cholerae infection: C00698
hsa05031__97	6.82943061252218e-25	DOWN	-10.3035777472986	5.21646346379235e-24	Amphetamine addiction: ARC
hsa03320__8	7.42357632152385e-25	DOWN	-10.2955522611262	5.57955996325732e-24	PPAR signaling pathway: GK
hsa04020__8	7.42357632152385e-25	DOWN	-10.2955522611262	5.57955996325732e-24	Calcium signaling pathway: PDE1A
hsa04530__14 20 43	7.42357632152385e-25	DOWN	-10.2955522611262	5.57955996325732e-24	Tight junction: CTNNA1 ACTB ACTN4
hsa04916__6	7.42357632152385e-25	DOWN	-10.2955522611262	5.57955996325732e-24	Melanogenesis: DCT
hsa04066__48	7.51253382923157e-25	DOWN	-10.2944057631016	5.62392472714188e-24	HIF-1 signaling pathway: PFKFB3
hsa05110__13	8.46193254853204e-25	DOWN	-10.2829407828553	6.30951240424274e-24	Vibrio cholerae infection: C00238
hsa05168__106 134	8.56357275419903e-25	UP	10.2817942848307	6.3600605553913e-24	Herpes simplex infection: SRSF8 C1QBP
hsa04924__49	9.19698225010348e-25	DOWN	-10.274915296683	6.80359434958443e-24	Renin secretion: PDE1A
hsa04725__25	9.30697243510291e-25	UP	10.2737687986583	6.80459190877758e-24	Cholinergic synapse: CACNA1A
hsa04726__10	9.30697243510291e-25	DOWN	-10.2737687986583	6.80459190877758e-24	Serotonergic synapse: PRKACA
hsa05200__218	9.30697243510291e-25	DOWN	-10.2737687986583	6.80459190877758e-24	Pathways in cancer: CSF3R*
hsa04261__15 17	1.11220983135126e-24	DOWN	-10.256571328289	8.10016384925974e-24	Adrenergic signaling in cardiomyocytes: ACTC1 MYH6
hsa04913__21	1.12548771092245e-24	DOWN	-10.2554248302644	8.1338131108588e-24	Ovarian steroidogenesis: CYP17A1
hsa04913__22	1.12548771092245e-24	DOWN	-10.2554248302644	8.1338131108588e-24	Ovarian steroidogenesis: CYP17A1*
hsa04919__42	1.23752110072513e-24	UP	10.2462528460674	8.90920363318975e-24	Thyroid hormone signaling pathway: SLC2A1
hsa04370__25	1.28232386306658e-24	DOWN	-10.2428133519935	9.19651350649655e-24	VEGF signaling pathway: PXN
hsa05200__212	1.37680575644232e-24	DOWN	-10.2359343638457	9.83657040439209e-24	Pathways in cancer: CCND1***
hsa04010__58	1.39320979130392e-24	UP	10.2347878658211	9.91606514340935e-24	MAPK signaling pathway: CDC25B
hsa04919__40	1.46078479712333e-24	DOWN	-10.2302018737226	1.03577910709236e-23	Thyroid hormone signaling pathway: RCAN2
hsa04916__7	1.47817977811619e-24	DOWN	-10.229055375698	1.04417285830087e-23	Melanogenesis: TYRP1
hsa04010__65	1.58694353822526e-24	UP	10.2221763875503	1.11680408551508e-23	MAPK signaling pathway: ELK4
hsa04728__44	1.6638198726825e-24	DOWN	-10.2175903954518	1.16653639580985e-23	Dopaminergic synapse: FOS
hsa05120__20	1.70363019574339e-24	UP	10.2152973994025	1.19000785791889e-23	Epithelial cell signaling in Helicobacter pylori infection: CXCL8
hsa04066__47	1.74438397443056e-24	DOWN	-10.2130044033533	1.20948246788008e-23	HIF-1 signaling pathway: PGK1
hsa05205__451	1.74438397443056e-24	DOWN	-10.2130044033533	1.20948246788008e-23	Proteoglycans in cancer: KDR**
hsa04024__118	1.7651215582391e-24	DOWN	-10.2118579053286	1.21936154703355e-23	cAMP signaling pathway: MYL9
hsa04960__4	1.78609801993883e-24	DOWN	-10.210711407304	1.22933266647072e-23	Aldosterone-regulated sodium reabsorption: ATP1B4
hsa04066__61	1.82881097049645e-24	DOWN	-10.2084184112548	1.25413715823461e-23	HIF-1 signaling pathway: HMOX1
hsa04114__59	1.85054259773268e-24	UP	10.2072719132301	1.26442528768717e-23	Oocyte meiosis: REC8*
hsa04660__43	1.98640965494847e-24	DOWN	-10.2003929250824	1.35234193537977e-23	T cell receptor signaling pathway: RHOA
hsa05161__45	2.0338591285582e-24	UP	10.1980999290331	1.37964667962486e-23	Hepatitis B: PCNA
hsa04911__31	2.08243118083959e-24	DOWN	-10.1958069329839	1.40751373697755e-23	Insulin secretion: CAMK2A
hsa04022__43	2.4273876287626e-24	DOWN	-10.1809024586638	1.63478901593008e-23	cGMP-PKG signaling pathway: MAPK1
hsa05152__94	2.45615531901904e-24	DOWN	-10.1797559606392	1.64825565872742e-23	Tuberculosis: CAMP
hsa04550__69	2.63599209033071e-24	DOWN	-10.1728769724914	1.75639331125227e-23	Signaling pathways regulating pluripotency of stem cells: ID1
hsa04961__12	2.63599209033071e-24	DOWN	-10.1728769724914	1.75639331125227e-23	Endocrine and other factor-regulated calcium reabsorption: SLC8A1
hsa05150__13	2.66720769654159e-24	DOWN	-10.1717304744668	1.77091281335747e-23	Staphylococcus aureus infection: C5AR1
hsa05166__132 136	2.73074158892226e-24	UP	10.1694374784175	1.80671248083976e-23	HTLV-I infection: CREBBP TP53
hsa04350__10	2.76306842930034e-24	UP	10.1682909803929	1.82168616794924e-23	TGF-beta signaling pathway: SMAD4
hsa04066__29	2.96514529044954e-24	DOWN	-10.1614119922452	1.94807972054359e-23	HIF-1 signaling pathway: LDHA
hsa05231__39	3.03570499998864e-24	UP	10.1591189961959	1.98748769859884e-23	Choline metabolism in cancer: EIF4EBP1
hsa05031__98	3.07160602831604e-24	DOWN	-10.1579724981713	2.00400962750203e-23	Amphetamine addiction: FOS
hsa04022__37 38	3.10792758366135e-24	DOWN	-10.1568260001467	2.02069063311407e-23	cGMP-PKG signaling pathway: ATP2A1 PLN
hsa04340__17	3.45456887032798e-24	UP	10.1465075179251	2.23832238184354e-23	Hedgehog signaling pathway: SMO
hsa04022__45	3.5366553260058e-24	DOWN	-10.1442145218758	2.28363414349309e-23	cGMP-PKG signaling pathway: CREB3
hsa04370__28	3.62067343413245e-24	DOWN	-10.1419215258266	2.32192675178665e-23	VEGF signaling pathway: SHC2
hsa05132__54	3.62067343413245e-24	DOWN	-10.1419215258266	2.32192675178665e-23	Salmonella infection: IL1B
hsa04071__11	3.66342088115115e-24	DOWN	-10.1407750278019	2.34134960397382e-23	Sphingolipid signaling pathway: PRKCA
hsa04623__25	3.93060773979898e-24	DOWN	-10.1338960396542	2.50359726884145e-23	Cytosolic DNA-sensing pathway: NFKB1*
hsa05217__19	4.07135070096451e-24	DOWN	-10.1304565455803	2.58448242132173e-23	Basal cell carcinoma: HHIP
hsa04932__58	4.36798219642736e-24	UP	10.1235775574326	2.76344732225152e-23	Non-alcoholic fatty liver disease (NAFLD): BAX
hsa04010__131	4.74119548399833e-24	UP	10.1155520712602	2.9894987632325e-23	MAPK signaling pathway: MYC
hsa05211__43	5.20652123642905e-24	DOWN	-10.1063800870632	3.27192421513384e-23	Renal cell carcinoma: RAP1A
hsa04360__96	5.99058794611894e-24	UP	10.0926221107677	3.75210491691916e-23	Axon guidance: GSK3B
hsa05200__209	6.27709379720781e-24	DOWN	-10.0880361186692	3.91849144350614e-23	Pathways in cancer: FIGF**
hsa04550__60	6.3508155115827e-24	UP	10.0868896206446	3.95138488286884e-23	Signaling pathways regulating pluripotency of stem cells: MAPK14
hsa04210__84	7.30526419589914e-24	DOWN	-10.0731316443491	4.53022819277046e-23	Apoptosis: FAS**
hsa04914__29	8.01900990246516e-24	UP	10.0639596601521	4.9564867127408e-23	Progesterone-mediated oocyte maturation: CDK2
hsa04742__47	8.20815865079169e-24	UP	10.0616666641029	5.05676396879921e-23	Taste transduction: GABRA1
hsa04550__53 64	9.1147806730407e-24	DOWN	-10.0513481818812	5.59695192308611e-23	Signaling pathways regulating pluripotency of stem cells: SMAD1 SMAD4
hsa04066__37	9.32934642500234e-24	DOWN	-10.049055185832	5.71004623211055e-23	HIF-1 signaling pathway: PDHA1
hsa04062__38	1.00035152619376e-23	DOWN	-10.0421761976842	6.10279388869506e-23	Chemokine signaling pathway: NCF1
hsa05142__7	1.21591531650355e-23	DOWN	-10.0226857312656	7.3868824732832e-23	Chagas disease (American trypanosomiasis): C1QA
hsa05200__215	1.21869801315476e-23	DOWN	-10.0226857312656	7.3868824732832e-23	Pathways in cancer: CSF1R
hsa04022__3	1.66625320918931e-23	DOWN	-9.99173028460077	1.00671697108254e-22	cGMP-PKG signaling pathway: MYL9
hsa04530__11 20 16	1.72508075426898e-23	DOWN	-9.9882907905269	1.03891882604853e-22	Tight junction: TJP1 ACTB CTTN
hsa04066__60	1.74514336128484e-23	DOWN	-9.98714429250227	1.04099186535054e-22	HIF-1 signaling pathway: NOS3
hsa04723__42	1.74514336128484e-23	DOWN	-9.98714429250227	1.04099186535054e-22	Retrograde endocannabinoid signaling: KCNJ3
hsa04723__50	1.74514336128484e-23	DOWN	-9.98714429250227	1.04099186535054e-22	Retrograde endocannabinoid signaling: KCNJ3*
hsa04020__64	1.8489749400646e-23	DOWN	-9.98141180237915	1.09252324288723e-22	Calcium signaling pathway: C01330*
hsa04020__12	1.8489749400646e-23	DOWN	-9.98141180237915	1.09252324288723e-22	Calcium signaling pathway: C01330
hsa04933__28	1.8489749400646e-23	DOWN	-9.98141180237915	1.09252324288723e-22	AGE-RAGE signaling pathway in diabetic complications: VCAM1
hsa04750__40	1.91418623524661e-23	DOWN	-9.97797230830528	1.12750969781454e-22	Inflammatory mediator regulation of TRP channels: C00219
hsa04390__58	2.05151761217618e-23	DOWN	-9.97109332015753	1.2046254978997e-22	Hippo signaling pathway: SMAD7
hsa04664__46	2.09942845781848e-23	DOWN	-9.96880032410828	1.22891777951431e-22	Fc epsilon RI signaling pathway: PLA2G4B
hsa04610__46	2.35611402287094e-23	DOWN	-9.95733534386204	1.37488765496102e-22	Complement and coagulation cascades: C2
hsa05200__213	2.38343172970253e-23	DOWN	-9.95618884583742	1.38652266876503e-22	Pathways in cancer: CSF2RA
hsa05166__89 90	2.41106302964889e-23	DOWN	-9.95504234781279	1.39826772614514e-22	HTLV-I infection: CHUK IKBKG
hsa04660__44	2.4958743204144e-23	DOWN	-9.95160285373892	1.4429993378642e-22	T cell receptor signaling pathway: PAK4
hsa05161__66 67	2.67445776680638e-23	DOWN	-9.94472386559118	1.54150495209485e-22	Hepatitis B: NFKB1 NFKBIA
hsa04115__64	2.73675275995546e-23	UP	9.94243086954193	1.57258667766248e-22	p53 signaling pathway: PMAIP1
hsa04071__66	2.86568480490607e-23	DOWN	-9.93784487744343	1.63666314541596e-22	Sphingolipid signaling pathway: C01245
hsa05130__9	2.86568480490607e-23	DOWN	-9.93784487744343	1.63666314541596e-22	Pathogenic Escherichia coli infection: TLR4
hsa04612__17 28	2.89884651492992e-23	DOWN	-9.93669837941881	1.65058563683434e-22	Antigen processing and presentation: CD4 HLA-DMA
hsa05152__24 25	3.07042356539387e-23	DOWN	-9.93096588929568	1.74299875509821e-22	Tuberculosis: ITGB2 ITGAM
hsa04919__100	3.40503093444992e-23	DOWN	-9.92064740707407	1.92712443549139e-22	Thyroid hormone signaling pathway: CTNNB1*
hsa04010__63	3.484152338998e-23	UP	9.91835441102482	1.96598265614932e-22	MAPK signaling pathway: MAX
hsa04115__54	4.04470163496674e-23	UP	9.9034499367047	2.27544741679716e-22	p53 signaling pathway: PERP
hsa04971__52 53	4.1862418133046e-23	DOWN	-9.90001044263083	2.33410930777429e-22	Gastric acid secretion: EZR ACTB
hsa05205__129	4.1862418133046e-23	DOWN	-9.90001044263083	2.33410930777429e-22	Proteoglycans in cancer: AKT3*
hsa05211__46	4.1862418133046e-23	DOWN	-9.90001044263083	2.33410930777429e-22	Renal cell carcinoma: AKT3
hsa04062__22 41	4.48419704036171e-23	DOWN	-9.89313145448308	2.49284208249694e-22	Chemokine signaling pathway: CRK PTK2B
hsa05160__53	4.58810790899296e-23	UP	9.89083845843383	2.53560434146993e-22	Hepatitis C: EIF2S1
hsa05162__74	4.58810790899296e-23	UP	9.89083845843383	2.53560434146993e-22	Measles: EIF2S1
hsa04742__8	4.69438908448452e-23	DOWN	-9.88854546238458	2.58673228438311e-22	Taste transduction: PLCB2
hsa05164__36	4.74846003755584e-23	DOWN	-9.88739896435996	2.60887614344077e-22	Influenza A: IL33
hsa04010__61	5.02813295946429e-23	UP	9.88166647423684	2.75447866788146e-22	MAPK signaling pathway: ATF4
hsa05218__21	5.2037011699665e-23	UP	9.87822698016297	2.83413173865712e-22	Melanoma: RB1
hsa05220__40	5.2037011699665e-23	UP	9.87822698016297	2.83413173865712e-22	Chronic myeloid leukemia: RB1
hsa04933__27	5.50989979525181e-23	DOWN	-9.87249449003984	2.99222592927114e-22	AGE-RAGE signaling pathway in diabetic complications: TNF
hsa04062__8 41	6.10667093766956e-23	DOWN	-9.86217600781823	3.30675351351041e-22	Chemokine signaling pathway: PXN PTK2B
hsa04610__44	6.24773968101845e-23	DOWN	-9.85988301176898	3.3637544013277e-22	Complement and coagulation cascades: C3
hsa04971__55	6.24773968101845e-23	DOWN	-9.85988301176898	3.3637544013277e-22	Gastric acid secretion: MYLK4
hsa04014__30	6.31947909700246e-23	DOWN	-9.85873651374435	3.38299180150075e-22	Ras signaling pathway: C01245
hsa04360__114	6.31947909700246e-23	DOWN	-9.85873651374435	3.38299180150075e-22	Axon guidance: RAF1
hsa04310__36	7.00295030249085e-23	UP	9.84841803152273	3.73822261885804e-22	Wnt signaling pathway: MYC
hsa05205__140	7.49874836695228e-23	DOWN	-9.84153904337499	3.99154339419358e-22	Proteoglycans in cancer: MAPK1***
hsa04724__66	9.41602471271698e-23	DOWN	-9.8186090828825	4.9979408009026e-22	Glutamatergic synapse: PLA2G4B
hsa04916__8	1.05492649937873e-22	DOWN	-9.80714410263626	5.58368138685249e-22	Melanogenesis: TYR*
hsa04062__33	1.06697576235703e-22	DOWN	-9.80599760461164	5.6315939816541e-22	Chemokine signaling pathway: WAS
hsa04666__50 52	1.11655034545036e-22	DOWN	-9.80141161251314	5.87674537563371e-22	Fc gamma R-mediated phagocytosis: DNM2 AMPH
hsa04933__26	1.1292961204228e-22	DOWN	-9.80026511448851	5.92722740300122e-22	AGE-RAGE signaling pathway in diabetic complications: IL6
hsa04910__26	1.14218590582106e-22	UP	9.79911861646389	5.9781819416094e-22	Insulin signaling pathway: RPS6
hsa04071__48	1.22260332602369e-22	DOWN	-9.79223962831614	6.38131013777365e-22	Sphingolipid signaling pathway: SMPD1
hsa04010__68	1.23658420292347e-22	UP	9.79109313029152	6.4009413699537e-22	MAPK signaling pathway: ATF2
hsa04670__45	1.23658420292347e-22	DOWN	-9.79109313029152	6.4009413699537e-22	Leukocyte transendothelial migration: PXN
hsa05034__84	1.23658420292347e-22	DOWN	-9.79109313029152	6.4009413699537e-22	Alcoholism: FOSB
hsa04530__4 37 11	1.51627197222934e-22	DOWN	-9.77045616584828	7.82712921928276e-22	Tight junction: OCLN TJP3 TJP1
hsa05205__45 46	1.65987504493281e-22	UP	9.76128418165129	8.54494577925684e-22	Proteoglycans in cancer: PAK1 FLNA
hsa04726__64	1.73664469741027e-22	UP	9.75669818955279	8.91572509954618e-22	Serotonergic synapse: CASP3
hsa05160__15 16	1.9008813178651e-22	DOWN	-9.7475262053558	9.7323051669442e-22	Hepatitis C: TRAF6 RIPK1
hsa04210__75	2.08047670428853e-22	UP	9.7383542211588	1.06228688243428e-21	Apoptosis: BAK1*
hsa04062__53	2.1279389744265e-22	DOWN	-9.73606122510955	1.08357651299387e-21	Chemokine signaling pathway: NFKB1
hsa04068__57	2.22610174587377e-22	DOWN	-9.73147523301106	1.12745153113122e-21	FoxO signaling pathway: IL7R
hsa04261__15 16	2.22610174587377e-22	DOWN	-9.73147523301106	1.12745153113122e-21	Adrenergic signaling in cardiomyocytes: ACTC1 TPM1
hsa04933__63	2.25133466051572e-22	DOWN	-9.73032873498643	1.13716608255619e-21	AGE-RAGE signaling pathway in diabetic complications: SELE
hsa05205__30	2.35512843050859e-22	DOWN	-9.72574274288793	1.18640383939025e-21	Proteoglycans in cancer: FLNA
hsa04919__49	2.72619230837538e-22	DOWN	-9.71083826856782	1.36965651000998e-21	Thyroid hormone signaling pathway: ACTB
hsa04390__75	2.88395254676559e-22	DOWN	-9.7051057784447	1.44505248943268e-21	Hippo signaling pathway: NKD1
hsa04062__35 36 37	2.91655491849645e-22	DOWN	-9.70395928042007	1.45750177974862e-21	Chemokine signaling pathway: PARD3 PRKCZ TIAM1
hsa04330__19	3.01656656429162e-22	DOWN	-9.7005197863462	1.50348238045198e-21	Notch signaling pathway: DTX2
hsa04650__116	4.22338539295656e-22	DOWN	-9.66612484560747	2.09940242152523e-21	Natural killer cell mediated cytotoxicity: FCGR3A
hsa04310__32	4.516783147599e-22	UP	9.65924585745972	2.23932335998378e-21	Wnt signaling pathway: PPARD
hsa05205__319	5.05124279172049e-22	DOWN	-9.64778087721348	2.49770663306389e-21	Proteoglycans in cancer: KDR
hsa04933__59	5.10801349541293e-22	DOWN	-9.64663437918886	2.51914891282963e-21	AGE-RAGE signaling pathway in diabetic complications: SERPINE1
hsa04064__133	5.22345581453277e-22	DOWN	-9.64434138313961	2.56263015026294e-21	NF-kappa B signaling pathway: CXCL2
hsa05223__28	5.22345581453277e-22	UP	9.64434138313961	2.56263015026294e-21	Non-small cell lung cancer: RB1
hsa04370__14	5.71161439243829e-22	DOWN	-9.63516939894261	2.79482381338321e-21	VEGF signaling pathway: PTGS2
hsa04970__21	5.84054624474567e-22	DOWN	-9.63287640289337	2.85048997243561e-21	Salivary secretion: ITPR1
hsa05031__10	6.17561263965745e-22	DOWN	-9.62714391277024	2.99844344959079e-21	Amphetamine addiction: CACNA1C
hsa05031__53	6.17561263965745e-22	DOWN	-9.62714391277024	2.99844344959079e-21	Amphetamine addiction: CACNA1C*
hsa04727__13	6.38571034110023e-22	UP	9.62370441869637	3.09246127085756e-21	GABAergic synapse: CACNA1A
hsa05205__150	6.45728550053722e-22	DOWN	-9.62255792067175	3.11109529174371e-21	Proteoglycans in cancer: PRKCA
hsa04066__5	6.45730262788743e-22	DOWN	-9.62255792067175	3.11109529174371e-21	HIF-1 signaling pathway: VEGFA
hsa04921__33	7.13843556924169e-22	DOWN	-9.61223943845013	3.43046558429799e-21	Oxytocin signaling pathway: C00942
hsa04530__30	7.71693964756285e-22	UP	9.60421395227776	3.6990126524925e-21	Tight junction: AKT3
hsa05016__48	8.15832594199244e-22	DOWN	-9.59848146215464	3.89073463071162e-21	Huntington's disease: HIP1
hsa05016__46	8.15832594199244e-22	DOWN	-9.59848146215464	3.89073463071162e-21	Huntington's disease: HTT**
hsa03320__61	8.24955546634811e-22	DOWN	-9.59733496413001	3.92428220791597e-21	PPAR signaling pathway: APOA1
hsa04727__49	8.52934419701295e-22	UP	9.59389547005614	4.0471307439867e-21	GABAergic synapse: GABRR3
hsa04520__73	9.96427043263023e-22	UP	9.5778444977114	4.71608668587209e-21	Adherens junction: PARD3
hsa04630__1	1.08889067622103e-21	UP	9.56867251351441	5.1407677905008e-21	Jak-STAT signaling pathway: MYC
hsa05164__20	1.11330285395567e-21	DOWN	-9.56637951746516	5.24284727464338e-21	Influenza A: ATF2
hsa04022__60	1.12571122462367e-21	DOWN	-9.56523301944053	5.28802847766967e-21	cGMP-PKG signaling pathway: TRPC6*
hsa04530__20 31	1.13825641256484e-21	DOWN	-9.56408652141591	5.32035770947594e-21	Tight junction: ACTB MLLT4
hsa05032__38	1.13825641256484e-21	UP	9.56408652141591	5.32035770947594e-21	Morphine addiction: CACNA1A
hsa05160__55	1.3291203565512e-21	UP	9.54803554907117	6.19706488823747e-21	Hepatitis C: MAPK14
hsa04666__38	1.42031162287767e-21	DOWN	-9.54115656092342	6.60585529551273e-21	Fc gamma R-mediated phagocytosis: CFL1
hsa04380__72	1.45206335360807e-21	DOWN	-9.53886356487417	6.73685689241866e-21	Osteoclast differentiation: MAPK1
hsa04520__44 47	1.46820155476919e-21	DOWN	-9.53771706684955	6.79495251579139e-21	Adherens junction: ACTB TJP1
hsa05222__44	1.51768846572499e-21	UP	9.53427757277568	7.00672389950185e-21	Small cell lung cancer: RB1
hsa04390__5	1.55159287994347e-21	UP	9.53198457672643	7.14569367993575e-21	Hippo signaling pathway: SAV1
hsa03320__9	1.60385926593565e-21	DOWN	-9.52854508265255	7.35036966022706e-21	PPAR signaling pathway: PCK1
hsa05030__73	1.60385926593565e-21	DOWN	-9.52854508265255	7.35036966022706e-21	Cocaine addiction: NFKB1
hsa05161__207	1.79098164109064e-21	UP	9.51708010240631	8.16809345536241e-21	Hepatitis B: CDK2
hsa05161__219	1.79098164109064e-21	UP	9.51708010240631	8.16809345536241e-21	Hepatitis B: CDK2*
hsa04022__49	2.30729942022662e-21	DOWN	-9.49071064783995	1.04720183831058e-20	cGMP-PKG signaling pathway: ATP1B4
hsa05211__31	2.30729942022662e-21	DOWN	-9.49071064783995	1.04720183831058e-20	Renal cell carcinoma: SOS1
hsa04810__31	2.3586101675677e-21	DOWN	-9.4884176517907	1.06791048309872e-20	Regulation of actin cytoskeleton: MSN
hsa05205__284	2.41104944135024e-21	DOWN	-9.48612465574146	1.08902930295603e-20	Proteoglycans in cancer: PRKCA*
hsa04014__55	2.46464178055784e-21	DOWN	-9.48383165969221	1.11056640423698e-20	Ras signaling pathway: MLLT4
hsa05152__20	2.60378619694058e-21	DOWN	-9.47809916956908	1.17045795790702e-20	Tuberculosis: FCGR1A
hsa05161__32	2.84288122310684e-21	DOWN	-9.46892718537209	1.2748863527966e-20	Hepatitis B: STAT3
hsa05133__24	3.03629641362115e-21	DOWN	-9.46204819722434	1.35515462261144e-20	Pertussis: NFKB1
hsa05205__369	3.03629641362115e-21	UP	9.46204819722434	1.35515462261144e-20	Proteoglycans in cancer: HOXD10
hsa05152__88 89	3.69808934784772e-21	DOWN	-9.44141123278111	1.64661371673125e-20	Tuberculosis: ITGAX ITGB2
hsa04530__4 45	3.77991591439682e-21	DOWN	-9.43911823673186	1.67906903147793e-20	Tight junction: OCLN TJP2
hsa05152__69	4.30979358675102e-21	DOWN	-9.42536026043637	1.90992975224178e-20	Tuberculosis: HLA-DMA
hsa04064__94	4.55168050251385e-21	DOWN	-9.41962777031325	2.01237827393495e-20	NF-kappa B signaling pathway: BCL2L1*
hsa04530__4 53	4.70320784482913e-21	DOWN	-9.41618827623937	2.07449003296571e-20	Tight junction: OCLN OCLN
hsa04726__71	5.02138735730315e-21	UP	9.40930928809163	2.20964563100061e-20	Serotonergic synapse: CACNA1A
hsa04066__26	5.66098185077676e-21	DOWN	-9.39669780982076	2.48527684523587e-20	HIF-1 signaling pathway: C01245
hsa04020__22	5.84892271315107e-21	DOWN	-9.39325831574689	2.56180088065521e-20	Calcium signaling pathway: C00575
hsa04020__42	6.24370035497818e-21	DOWN	-9.38637932759914	2.72835185279163e-20	Calcium signaling pathway: MYLK4
hsa04920__12	6.73742814444624e-21	DOWN	-9.37835384142677	2.93726855763677e-20	Adipocytokine signaling pathway: C00165
hsa05205__120	6.96091767833546e-21	UP	9.3749143473529	3.0276769253686e-20	Proteoglycans in cancer: PLAU
hsa05164__78	8.19213822382891e-21	UP	9.35771687698353	3.55497176040982e-20	Influenza A: GSK3B
hsa04022__51	8.28148345005552e-21	DOWN	-9.35657037895891	3.58546253517381e-20	cGMP-PKG signaling pathway: GTF2I
hsa04921__53	9.4317979919597e-21	DOWN	-9.34281240266342	4.0741030866419e-20	Oxytocin signaling pathway: RGS2
hsa04630__27	9.53450203548686e-21	UP	9.34166590463879	4.10902048731188e-20	Jak-STAT signaling pathway: PIM1
hsa04270__24	1.00648468525782e-20	DOWN	-9.33593341451567	4.32765382974701e-20	Vascular smooth muscle contraction: ACTA2
hsa05164__31 32 33	1.01739836803315e-20	DOWN	-9.33478691649105	4.36459254231573e-20	Influenza A: NLRP3 PYCARD CASP1
hsa05030__77	1.02850611947169e-20	DOWN	-9.33364041846642	4.40219361842211e-20	Cocaine addiction: BDNF
hsa04064__116	1.08566608202133e-20	DOWN	-9.3279079283433	4.63628765481382e-20	NF-kappa B signaling pathway: GADD45B
hsa04015__96	1.10939977367013e-20	DOWN	-9.32561493229405	4.72689835538816e-20	Rap1 signaling pathway: PLCE1
hsa04750__59	1.17100216482351e-20	DOWN	-9.31988244217093	4.97808386358231e-20	Inflammatory mediator regulation of TRP channels: TRPV2
hsa04727__47	1.18372257126738e-20	DOWN	-9.31873594414631	5.02080070296028e-20	GABAergic synapse: CACNA1A*
hsa04014__61	1.27667317558994e-20	DOWN	-9.31071045797394	5.40285787597636e-20	Ras signaling pathway: RAP1A
hsa04923__26 27	1.30451861463836e-20	DOWN	-9.30841746192469	5.50829320652915e-20	Regulation of lipolysis in adipocytes: PNPLA2 ABHD5
hsa04910__9	1.31868534357372e-20	UP	9.30727096390006	5.55562726586326e-20	Insulin signaling pathway: ELK1
hsa04919__21 53	1.4375187632057e-20	DOWN	-9.29809897970307	6.04272428649554e-20	Thyroid hormone signaling pathway: THRA C02465
hsa04530__20 37	1.48476025427051e-20	DOWN	-9.2946594856292	6.22737615574616e-20	Tight junction: ACTB TJP3
hsa04630__24	1.51710410753434e-20	UP	9.29236648957995	6.34886106471499e-20	Jak-STAT signaling pathway: MCL1
hsa04750__53	1.5669304688262e-20	UP	9.28892699550608	6.54280522427652e-20	Inflammatory mediator regulation of TRP channels: TRPM8
hsa04062__60	1.618374343095e-20	UP	9.2854875014322	6.71285958206512e-20	Chemokine signaling pathway: GSK3A
hsa04723__73	1.618374343095e-20	DOWN	-9.2854875014322	6.71285958206512e-20	Retrograde endocannabinoid signaling: MAPK14*
hsa04723__68	1.618374343095e-20	DOWN	-9.2854875014322	6.71285958206512e-20	Retrograde endocannabinoid signaling: MAPK14
hsa04370__39	1.68957221330817e-20	DOWN	-9.28090150933371	6.99274490926444e-20	VEGF signaling pathway: RAC1
hsa03320__55	1.78293812213277e-20	DOWN	-9.27516901921058	7.36294666260982e-20	PPAR signaling pathway: SCD
hsa04012__21	1.80221450000111e-20	UP	9.27402252118596	7.42623036294318e-20	ErbB signaling pathway: GSK3B
hsa05134__71	1.90173085405799e-20	DOWN	-9.26829003106284	7.81915158594083e-20	Legionellosis: CXCL8
hsa04152__49	1.94304173666077e-20	UP	9.26599703501359	7.97156205935718e-20	AMPK signaling pathway: GYS1
hsa05150__14	2.02832854876335e-20	DOWN	-9.26141104291509	8.30333190223601e-20	Staphylococcus aureus infection: FPR1
hsa05145__33	2.05024112266774e-20	DOWN	-9.26026454489047	8.35662271039629e-20	Toxoplasmosis: STAT3
hsa05169__125	2.05024112266774e-20	DOWN	-9.26026454489047	8.35662271039629e-20	Epstein-Barr virus infection: STAT3
hsa05134__73	2.14019342441287e-20	DOWN	-9.25567855279197	8.7043797499389e-20	Legionellosis: CXCL1
hsa05211__23	2.18662183367516e-20	DOWN	-9.25338555674272	8.87400091895384e-20	Renal cell carcinoma: PDGFB
hsa04630__36	2.25813773386652e-20	UP	9.24994606266885	9.14448448692929e-20	Jak-STAT signaling pathway: GFAP
hsa05166__120	2.56806849872114e-20	UP	9.23618808637336	1.03772058260151e-19	HTLV-I infection: E2F1
hsa05200__211	2.88892772036817e-20	DOWN	-9.22357660810249	1.16487021171068e-19	Pathways in cancer: CXCL8
hsa04310__20	3.08032834887686e-20	DOWN	-9.21669761995475	1.23938693095067e-19	Wnt signaling pathway: MAPK8
hsa04211__62	3.21483937609249e-20	UP	9.21211162785625	1.29074427087132e-19	Longevity regulating pathway - mammal: EHMT2
hsa05134__59	3.31951817436309e-20	UP	9.20867213378238	1.3299306289186e-19	Legionellosis: HSPA1A
hsa04010__66	3.65419635143876e-20	UP	9.19835365156076	1.46090105199009e-19	MAPK signaling pathway: TP53
hsa04014__38	3.97956053982775e-20	DOWN	-9.18918166736376	1.58759962937077e-19	Ras signaling pathway: MAPK8
hsa04742__54	4.52171171304735e-20	DOWN	-9.17542369106827	1.79625714774122e-19	Taste transduction: P2RX2*
hsa04742__40	4.52171171304735e-20	DOWN	-9.17542369106827	1.79625714774122e-19	Taste transduction: P2RX2
hsa04015__63	4.76905168713426e-20	DOWN	-9.16969120094515	1.88653644634216e-19	Rap1 signaling pathway: GNAI1
hsa04960__27	4.76905168713426e-20	DOWN	-9.16969120094515	1.88653644634216e-19	Aldosterone-regulated sodium reabsorption: KCNJ1
hsa04066__43	4.82003616200587e-20	DOWN	-9.16854470292052	1.90269914882543e-19	HIF-1 signaling pathway: PFKL
hsa05216__5	4.92362691740304e-20	UP	9.16625170687128	1.93951676683445e-19	Thyroid cancer: MAPK1
hsa04950__1	5.02941786428177e-20	DOWN	-9.16395871082203	1.97704522321871e-19	Maturity onset diabetes of the young: HNF1B
hsa04211__42	5.08315279814916e-20	DOWN	-9.1628122127974	1.99399668219672e-19	Longevity regulating pathway - mammal: PPARGC1A
hsa04014__44	5.13745516504855e-20	DOWN	-9.16166571477278	2.01109963648463e-19	Ras signaling pathway: ETS1
hsa04740__42	5.59302504023164e-20	DOWN	-9.15249373057578	2.1803514627791e-19	Olfactory transduction: PDE2A
hsa05220__4	5.59302504023164e-20	DOWN	-9.15249373057578	2.1803514627791e-19	Chronic myeloid leukemia: PTPN11
hsa04713__60	5.77396928291893e-20	DOWN	-9.14905423650191	2.2462294580962e-19	Circadian entrainment: PER1
hsa04723__9	5.83556049136212e-20	DOWN	-9.14790773847729	2.25617657680441e-19	Retrograde endocannabinoid signaling: PRKCA
hsa04725__20	5.83556049136212e-20	DOWN	-9.14790773847729	2.25617657680441e-19	Cholinergic synapse: PRKCA
hsa04726__18	5.83556049136212e-20	DOWN	-9.14790773847729	2.25617657680441e-19	Serotonergic synapse: PRKCA
hsa04062__25	5.89780103037405e-20	DOWN	-9.14676124045266	2.27555813882399e-19	Chemokine signaling pathway: ROCK1
hsa05134__7	7.28991410596831e-20	DOWN	-9.12383127996018	2.80691569776936e-19	Legionellosis: IL18
hsa05120__53	7.60504478565631e-20	UP	9.11924528786168	2.92226567530638e-19	Epithelial cell signaling in Helicobacter pylori infection: GIT1
hsa04919__28	8.01794885689318e-20	DOWN	-9.11351279773856	3.07463793920455e-19	Thyroid hormone signaling pathway: RCAN1
hsa04750__51	9.00572347408416e-20	UP	9.10090131946769	3.43938097719596e-19	Inflammatory mediator regulation of TRP channels: TRPV4
hsa04750__61	9.00572347408416e-20	UP	9.10090131946769	3.43938097719596e-19	Inflammatory mediator regulation of TRP channels: TRPV4*
hsa04919__32	9.29566422987223e-20	DOWN	-9.09746182539382	3.54291137686205e-19	Thyroid hormone signaling pathway: PLN
hsa04728__60	9.69634065715301e-20	UP	9.09287583329532	3.68814252930982e-19	Dopaminergic synapse: CACNA1A
hsa04972__18	9.90303233070494e-20	DOWN	-9.09058283724607	3.75915106048375e-19	Pancreatic secretion: PRKCA
hsa04360__4	1.0008005059991e-19	DOWN	-9.08943633922145	3.79133901365385e-19	Axon guidance: GNAI1*
hsa04152__38	1.03295663093931e-19	UP	9.08599684514757	3.9052827153621e-19	AMPK signaling pathway: PFKL
hsa04350__44 45	1.04390060581705e-19	UP	9.08485034712295	3.9387334103017e-19	TGF-beta signaling pathway: TGFBR2 TGFBR1
hsa05132__41	1.14769716092847e-19	UP	9.07453186490133	4.32168930938798e-19	Salmonella infection: ACTB*
hsa04310__34	1.1598417164099e-19	UP	9.07338536687671	4.35868517026842e-19	Wnt signaling pathway: FOSL1
hsa04370__36	1.2354221390757e-19	DOWN	-9.06650637872896	4.63344949964718e-19	VEGF signaling pathway: NOS3
hsa04728__68	1.26168154218379e-19	DOWN	-9.06421338267971	4.72250919873175e-19	Dopaminergic synapse: CACNA1C
hsa04919__26	1.34381447299149e-19	DOWN	-9.05733439453197	5.01993517843145e-19	Thyroid hormone signaling pathway: THRB
hsa04152__35	1.35800780593396e-19	DOWN	-9.05618789650734	5.06289021299587e-19	AMPK signaling pathway: PFKFB1
hsa04921__54	1.38684037739894e-19	DOWN	-9.05389490045809	5.16014469135169e-19	Oxytocin signaling pathway: RCAN1
hsa05215__12	1.46159527112789e-19	DOWN	-9.04816241033497	5.42754449495911e-19	Prostate cancer: KLK3
hsa04810__82 83	1.5242545224109e-19	UP	9.04357641823648	5.64906163236701e-19	Regulation of actin cytoskeleton: ACTB ARPC5
hsa05032__25	1.60632252062691e-19	DOWN	-9.03784392811335	5.94149609499599e-19	Morphine addiction: C00575*
hsa04210__74	1.64035897902761e-19	UP	9.0355509320641	6.05547057287404e-19	Apoptosis: BAX*
hsa05134__72	1.67510793108957e-19	DOWN	-9.03325793601486	6.1716231421908e-19	Legionellosis: IL12A
hsa04630__31	1.69275418316259e-19	UP	9.03211143799023	6.22443270090511e-19	Jak-STAT signaling pathway: BCL2L1
hsa04010__54	1.76519486635298e-19	DOWN	-9.02752544589173	6.47812725366651e-19	MAPK signaling pathway: NR4A1
hsa05110__52	1.98058136855645e-19	DOWN	-9.01491396762087	7.2544101199173e-19	Vibrio cholerae infection: ADCY3
hsa04510__24 69	2.04370031342444e-19	DOWN	-9.011474473547	7.47103674888039e-19	Focal adhesion: ZYX ACTB
hsa04310__22	2.06517847746603e-19	DOWN	-9.01032797552237	7.52029139371835e-19	Wnt signaling pathway: ROCK2
hsa04713__61	2.06517847746603e-19	DOWN	-9.01032797552237	7.52029139371835e-19	Circadian entrainment: FOS
hsa04360__20	2.08687965358109e-19	UP	9.00918147749775	7.58461676804422e-19	Axon guidance: ROCK1
hsa05200__203	2.10880612852711e-19	UP	9.00803497947312	7.64951103378849e-19	Pathways in cancer: TGFA*
hsa04152__24	2.22189965542455e-19	DOWN	-9.00230248935	8.04421859834824e-19	AMPK signaling pathway: SIRT1
hsa04066__51	2.24522725771689e-19	DOWN	-9.00115599132538	8.09747028262961e-19	HIF-1 signaling pathway: TFRC
hsa04151__105 62	2.24522725771689e-19	UP	9.00115599132538	8.09747028262961e-19	PI3K-Akt signaling pathway: CCND1 CDK2
hsa05030__76	2.26879682731909e-19	DOWN	-9.00000949330075	8.15118401249056e-19	Cocaine addiction: PDYN
hsa05200__188	2.26879682731909e-19	DOWN	-9.00000949330075	8.15118401249056e-19	Pathways in cancer: KLK3
hsa05214__52	2.36554472665158e-19	UP	8.99542350120226	8.48255446827923e-19	Glioma: E2F1*
hsa04925__33	2.49222882497157e-19	DOWN	-8.98969101107913	8.91980564213633e-19	Aldosterone synthesis and secretion: CYP11B2
hsa04540__10	2.65312306221816e-19	DOWN	-8.98281202293139	9.47760120514813e-19	Gap junction: C00533
hsa04932__138	2.76604407545151e-19	DOWN	-8.97822603083289	9.86223305080339e-19	Non-alcoholic fatty liver disease (NAFLD): CEBPA
hsa04666__51	2.85383886031376e-19	DOWN	-8.97478653675902	1.01559909441848e-18	Fc gamma R-mediated phagocytosis: NCF1
hsa04610__7	3.03777018440019e-19	DOWN	-8.96790754861127	1.07901137551757e-18	Complement and coagulation cascades: C00290
hsa04910__48	3.58748579506317e-19	DOWN	-8.94956358021728	1.27186524696674e-18	Insulin signaling pathway: PPARGC1A
hsa04971__37	3.66276827101408e-19	DOWN	-8.94727058416803	1.29610952565639e-18	Gastric acid secretion: KCNQ1
hsa04724__68	3.70099265976336e-19	DOWN	-8.94612408614341	1.30717391122093e-18	Glutamatergic synapse: MAPK1
hsa04973__5	3.97982419698424e-19	UP	8.93809859997104	1.40301869908694e-18	Carbohydrate digestion and absorption: SLC2A5
hsa04725__61	4.19159756600522e-19	DOWN	-8.93236610984792	1.47490858174603e-18	Cholinergic synapse: FOS
hsa05132__13	4.27939038595551e-19	DOWN	-8.93007311379867	1.50298589443185e-18	Salmonella infection: FOS
hsa04668__141	4.36899931942453e-19	DOWN	-8.92778011774942	1.52874296484147e-18	TNF signaling pathway: JUN*
hsa04742__34	4.36899931942453e-19	UP	8.92778011774942	1.52874296484147e-18	Taste transduction: GRM1
hsa04115__52 53	4.4144963896704e-19	UP	8.9266336197248	1.54179158293507e-18	p53 signaling pathway: CDK4 CCND1
hsa05133__27	4.55381462575201e-19	DOWN	-8.92319412565092	1.58749864226123e-18	Pertussis: IRF3
hsa04066__62	5.54268995463064e-19	DOWN	-8.90141066318306	1.92865081939833e-18	HIF-1 signaling pathway: NPPA
hsa04370__23	5.65838440025875e-19	DOWN	-8.89911766713381	1.96526881480336e-18	VEGF signaling pathway: PTK2
hsa05152__68	5.77646376071293e-19	DOWN	-8.89682467108456	2.00257848826192e-18	Tuberculosis: CD74
hsa04920__5	6.33865846594077e-19	DOWN	-8.88650618886295	2.19343264410731e-18	Adipocytokine signaling pathway: NFKBIA
hsa05133__73	6.60555760482133e-19	DOWN	-8.88192019676445	2.28158873887119e-18	Pertussis: FOS
hsa04115__17	6.8129885653493e-19	UP	8.87848070269058	2.34891844298923e-18	p53 signaling pathway: TP73
hsa04350__12	7.70902746538532e-19	UP	8.86472272639508	2.65297849953462e-18	TGF-beta signaling pathway: ACVR2A
hsa04923__52 53	7.78874981630156e-19	DOWN	-8.86357622837046	2.67551387656867e-18	Regulation of lipolysis in adipocytes: PNPLA2 ABHD5*
hsa04621__21 31 41	8.03283511613413e-19	DOWN	-8.86013673429659	2.74930731934718e-18	NOD-like receptor signaling pathway: NLRP3 CARD8 CASP1
hsa04660__34	8.03283511613413e-19	DOWN	-8.86013673429659	2.74930731934718e-18	T cell receptor signaling pathway: FOS
hsa04340__46	8.19974030288584e-19	DOWN	-8.85784373824734	2.80132945984045e-18	Hedgehog signaling pathway: PRKACA
hsa04370__15	8.37006993712898e-19	DOWN	-8.85555074219809	2.85433056476685e-18	VEGF signaling pathway: PLA2G4B
hsa04922__36	8.54389336541986e-19	UP	8.85325774614884	2.90832891913477e-18	Glucagon signaling pathway: GYS1
hsa04727__35	9.08704082413929e-19	DOWN	-8.8463787580011	3.08762200878078e-18	GABAergic synapse: PRKACA
hsa04520__34	9.76392834548386e-19	DOWN	-8.83835327182873	3.31162840454227e-18	Adherens junction: RHOA
hsa04012__40	1.0598643587469e-18	UP	8.82918128763173	3.58826149564942e-18	ErbB signaling pathway: ELK1*
hsa04620__87	1.08181020377428e-18	DOWN	-8.82688829158248	3.65597369225156e-18	Toll-like receptor signaling pathway: CCL4L1
hsa05221__21	1.09295081978004e-18	DOWN	-8.82574179355786	3.68699208324362e-18	Acute myeloid leukemia: PIM1
hsa04550__25	1.1622138740489e-18	UP	8.81886280541011	3.91361983752309e-18	Signaling pathways regulating pluripotency of stem cells: MAPK1
hsa04068__45	1.1741718223428e-18	DOWN	-8.81771630738549	3.94681369263348e-18	FoxO signaling pathway: RBL2
hsa05031__96	1.26134837000344e-18	DOWN	-8.80969082121312	4.23227426292225e-18	Amphetamine addiction: PDYN
hsa05134__6	1.28740934950208e-18	DOWN	-8.80739782516387	4.31201812426812e-18	Legionellosis: IL1B
hsa05200__187	1.30063853479301e-18	UP	8.80625132713925	4.34857616881863e-18	Pathways in cancer: WNT16*
hsa05205__189	1.38288008357872e-18	DOWN	-8.7993723389915	4.61533157556736e-18	Proteoglycans in cancer: IL12B
hsa04213__52	1.41141906080424e-18	DOWN	-8.79707934294225	4.70222768661555e-18	Longevity regulating pathway - multiple species: SOD2
hsa05161__195	1.45532145692492e-18	DOWN	-8.79363984886838	4.83990976559633e-18	Hepatitis B: IL6
hsa04390__78	1.47025316392528e-18	UP	8.79249335084375	4.88092878978022e-18	Hippo signaling pathway: SOX2
hsa04540__16 17	1.50057190492156e-18	DOWN	-8.79020035479451	4.97279472548079e-18	Gap junction: GJA1 GJA1**
hsa05211__48	1.53150790656534e-18	DOWN	-8.78790735874526	5.0663791486554e-18	Renal cell carcinoma: JUN
hsa04730__20	1.56307356972732e-18	DOWN	-8.78561436269601	5.15265831143445e-18	Long-term depression: C00025
hsa05032__13	1.56307356972732e-18	DOWN	-8.78561436269601	5.15265831143445e-18	Morphine addiction: PRKACA
hsa04921__55	1.62814471746151e-18	DOWN	-8.78102837059751	5.35776519108612e-18	Oxytocin signaling pathway: PTGS2*
hsa04932__28	1.6616762516371e-18	UP	8.77873537454826	5.45854838605963e-18	Non-alcoholic fatty liver disease (NAFLD): GSK3A
hsa04068__47	1.73079831016045e-18	DOWN	-8.77414938244977	5.66580143691898e-18	FoxO signaling pathway: GADD45G
hsa04068__54	1.73079831016045e-18	DOWN	-8.77414938244977	5.66580143691898e-18	FoxO signaling pathway: GADD45G*
hsa04064__96	2.25463809716398e-18	DOWN	-8.74434043380953	7.36776519055847e-18	NF-kappa B signaling pathway: BCL2A1
hsa04917__65	2.54651888227337e-18	DOWN	-8.73058245751404	8.30713364547162e-18	Prolactin signaling pathway: CYP17A1
hsa04931__140	2.76152191922745e-18	UP	8.72141047331705	8.99289373696425e-18	Insulin resistance: G00369
hsa04973__36	2.78962711977947e-18	DOWN	-8.72026397529242	9.06870131153222e-18	Carbohydrate digestion and absorption: SLC2A2
hsa04750__62	2.84662534622395e-18	UP	8.71797097924317	9.22228575354994e-18	Inflammatory mediator regulation of TRP channels: TRPM8*
hsa04916__4	2.84668745985043e-18	DOWN	-8.71797097924317	9.22228575354994e-18	Melanogenesis: TYR
hsa04923__43	2.96428724395943e-18	DOWN	-8.71338498714468	9.58673964096345e-18	Regulation of lipolysis in adipocytes: C00219
hsa05152__90	3.08668108070375e-18	DOWN	-8.70879899504618	9.96541881553669e-18	Tuberculosis: CR1
hsa04724__44	3.21406172460424e-18	DOWN	-8.70421300294768	1.03588713216662e-17	Glutamatergic synapse: PRKACA*
hsa04310__31	3.70213074169086e-18	UP	8.68816203060294	1.1911478876091e-17	Wnt signaling pathway: MMP7
hsa04380__32	3.77758119101164e-18	DOWN	-8.68586903455369	1.21334616374545e-17	Osteoclast differentiation: AKT3
hsa04071__89	3.93306525639558e-18	DOWN	-8.6812830424552	1.26113133391933e-17	Sphingolipid signaling pathway: C00533
hsa04730__30	4.0948639369353e-18	DOWN	-8.6766970503567	1.31077501490655e-17	Long-term depression: C00025*
hsa05220__21	4.76228459151663e-18	DOWN	-8.65949957998733	1.52182529718703e-17	Chronic myeloid leukemia: NFKBIA
hsa04115__2	5.4268167122377e-18	UP	8.64459510566722	1.73123745370028e-17	p53 signaling pathway: IGFBP3
hsa04650__25	5.70609425109353e-18	DOWN	-8.6388626155441	1.81724594878046e-17	Natural killer cell mediated cytotoxicity: SH2D1B
hsa04972__23	5.8217360254319e-18	DOWN	-8.63656961949485	1.85093773126676e-17	Pancreatic secretion: KCNMA1
hsa04010__134	5.88042138047861e-18	UP	8.63542312147023	1.86643779964853e-17	MAPK signaling pathway: ATF4*
hsa04210__59	5.93969059628322e-18	UP	8.6342766234456	1.88207059534843e-17	Apoptosis: PMAIP1
hsa04621__34 35	6.24499709361149e-18	DOWN	-8.62854413332248	1.97547972035286e-17	NOD-like receptor signaling pathway: CASP1 PYCARD
hsa04151__26	6.30789176626506e-18	DOWN	-8.62739763529786	1.99202161828774e-17	PI3K-Akt signaling pathway: RBL2
hsa04068__67	6.50035129046234e-18	DOWN	-8.62395814122398	2.04592296059945e-17	FoxO signaling pathway: GABARAP
hsa04919__44	6.50035129046234e-18	DOWN	-8.62395814122398	2.04592296059945e-17	Thyroid hormone signaling pathway: PFKFB2
hsa05166__114 112 113	6.7660062425993e-18	DOWN	-8.61937214912549	2.12597420231506e-17	HTLV-I infection: DLG1 CTNNB1 APC2
hsa05134__10	7.3298733142851e-18	DOWN	-8.61020016492849	2.29930416653451e-17	Legionellosis: NFKB1
hsa05164__77	8.10029483684622e-18	UP	8.59873518468225	2.53674233307234e-17	Influenza A: CASP9
hsa04390__90	9.13085923746795e-18	UP	8.58497720838676	2.84998081514988e-17	Hippo signaling pathway: BBC3
hsa04971__56	9.13085923746795e-18	DOWN	-8.58497720838676	2.84998081514988e-17	Gastric acid secretion: CAMK2A
hsa04014__42	9.31477193939513e-18	DOWN	-8.58268421233751	2.90256326270704e-17	Ras signaling pathway: PLA2G4B
hsa04210__72	1.04975595916049e-17	DOWN	-8.56892623604202	3.2603164417563e-17	Apoptosis: BCL2A1
hsa04621__29	1.04975595916049e-17	DOWN	-8.56892623604202	3.2603164417563e-17	NOD-like receptor signaling pathway: CASP5
hsa04210__85	1.06025670697092e-17	DOWN	-8.56777973801739	3.2874956310204e-17	Apoptosis: FASLG*
hsa04620__76	1.12547349036071e-17	DOWN	-8.56090074986965	3.48396159536701e-17	Toll-like receptor signaling pathway: CCL3L3
hsa04520__58	1.14798312460339e-17	UP	8.42102799086548	3.54779653146342e-17	Adherens junction: CDH1*
hsa05030__37	1.18283265118166e-17	DOWN	-8.55516825974652	3.64949515857199e-17	Cocaine addiction: PRKACA
hsa05211__41	1.19464596436481e-17	DOWN	-8.5540217617219	3.67990125744505e-17	Renal cell carcinoma: PDGFB*
hsa03320__59	1.2307889441033e-17	DOWN	-8.55058226764803	3.78502852040932e-17	PPAR signaling pathway: NR1H3
hsa04152__54	1.26801058765518e-17	DOWN	-8.54714277357415	3.89312401013739e-17	AMPK signaling pathway: SLC2A4*
hsa04510__42	1.28066296465932e-17	UP	8.54599627554953	3.92555580847447e-17	Focal adhesion: BIRC2
hsa04810__30	1.29343991013902e-17	DOWN	-8.54484977752491	3.95826317777072e-17	Regulation of actin cytoskeleton: VCL*
hsa04630__7	1.35923590364254e-17	UP	8.53911728740178	4.15285246007208e-17	Jak-STAT signaling pathway: BCL2
hsa04670__35	1.37278606785433e-17	DOWN	-8.53797078937716	4.18065643678813e-17	Leukocyte transendothelial migration: PTK2
hsa04740__16	1.37278606785433e-17	DOWN	-8.53797078937716	4.18065643678813e-17	Olfactory transduction: PRKG1
hsa04520__43	1.42833253178516e-17	DOWN	-8.53338479727866	4.34277803757981e-17	Adherens junction: ACTB
hsa04020__16	1.48609569143732e-17	UP	8.52879880518016	4.51110469177822e-17	Calcium signaling pathway: C06124
hsa04970__32	1.50089298535746e-17	DOWN	-8.52765230715554	4.54134930674183e-17	Salivary secretion: RYR3
hsa05200__65	1.50089298535746e-17	DOWN	-8.52765230715554	4.54134930674183e-17	Pathways in cancer: STK4
hsa05140__21	1.530925097237e-17	DOWN	-8.52535931110629	4.62477211850212e-17	Leishmaniasis: NFKB1
hsa05120__18	1.54616274530531e-17	DOWN	-8.52421281308167	4.66330625750992e-17	Epithelial cell signaling in Helicobacter pylori infection: CCL5
hsa05205__17	1.56155003073527e-17	DOWN	-8.52306631505704	4.70216748037112e-17	Proteoglycans in cancer: AKT3
hsa04713__14	1.57708840257714e-17	DOWN	-8.52191981703242	4.74135857350793e-17	Circadian entrainment: PRKCA
hsa05161__194	1.60862427097244e-17	DOWN	-8.51962682098317	4.82844250025113e-17	Hepatitis B: TNF*
hsa04810__21 82	1.64078222182044e-17	DOWN	-8.51733382493392	4.9171129103678e-17	Regulation of actin cytoskeleton: CFL1 ACTB
hsa05010__61	1.75841073105036e-17	UP	8.50930833876155	5.25286766874982e-17	Alzheimer's disease: GAPDH
hsa05020__52	1.75841073105036e-17	DOWN	-8.50930833876155	5.25286766874982e-17	Prion diseases: FYN
hsa04024__101	1.96027238341792e-17	UP	8.49669686049068	5.8465901721306e-17	cAMP signaling pathway: HCN4
hsa05213__27	2.27281896082566e-17	UP	8.47949939012132	6.76802983738734e-17	Endometrial cancer: ELK1
hsa05215__8	2.34098867708278e-17	DOWN	-8.47605989604745	6.95999639911162e-17	Prostate cancer: NFKBIA
hsa04660__56	2.4111748819908e-17	DOWN	-8.47262040197357	7.15734218524601e-17	T cell receptor signaling pathway: CD3E
hsa04350__11	2.66046005230941e-17	UP	8.46115542172733	7.88486504462047e-17	TGF-beta signaling pathway: SMAD4*
hsa05162__58	2.84992109937041e-17	DOWN	-8.45312993555496	8.43307361530237e-17	Measles: STAT3
hsa04211__52	2.90645626531075e-17	DOWN	-8.45083693950571	8.58684170207373e-17	Longevity regulating pathway - mammal: PPARG
hsa04623__9	2.99333965972289e-17	UP	8.44739744543184	8.82964712813078e-17	Cytosolic DNA-sensing pathway: IKBKE
hsa03320__53	3.2061568347392e-17	DOWN	-8.43937195925947	9.44258415748427e-17	PPAR signaling pathway: ADIPOQ
hsa04261__37	3.46769562541907e-17	DOWN	-8.43019997506248	1.0196870234996e-16	Adrenergic signaling in cardiomyocytes: CREB3
hsa04024__92	3.50183324213325e-17	UP	8.42905347703785	1.02811635343256e-16	cAMP signaling pathway: GRIN3A
hsa05134__9	3.6417303763098e-17	DOWN	-8.42446748493935	1.06752127567646e-16	Legionellosis: CASP7
hsa05150__69	3.67755741702493e-17	DOWN	-8.42332098691473	1.07634429697661e-16	Staphylococcus aureus infection: FPR2
hsa05231__38	3.78713774482509e-17	UP	8.41988149284086	1.10669235187035e-16	Choline metabolism in cancer: RPS6KB1
hsa04360__89	3.89993770655516e-17	UP	8.41644199876698	1.13788555133807e-16	Axon guidance: CAMK2A
hsa05166__32	3.93826920492818e-17	DOWN	-8.41529550074236	1.14728803659846e-16	HTLV-I infection: STAT5A
hsa04620__86	3.97697229452538e-17	DOWN	-8.41414900271774	1.1567694955748e-16	Toll-like receptor signaling pathway: IL12A
hsa05132__86	4.13557208629855e-17	DOWN	-8.40956301061924	1.20104172336244e-16	Salmonella infection: MYH9
hsa05014__2	4.17618706862887e-17	DOWN	-8.40841651259461	1.21096535523976e-16	Amyotrophic lateral sclerosis (ALS): SLC1A2
hsa05200__199	4.30040750098186e-17	DOWN	-8.40497701852074	1.24314856836076e-16	Pathways in cancer: BCL2L1**
hsa05220__3	4.30040750098186e-17	DOWN	-8.40497701852074	1.24314856836076e-16	Chronic myeloid leukemia: BCL2L1
hsa04919__45	4.34261877884395e-17	DOWN	-8.40383052049612	1.25342253232685e-16	Thyroid hormone signaling pathway: SLC9A1
hsa04919__102	4.88217009435364e-17	DOWN	-8.39007254420062	1.40699349805069e-16	Thyroid hormone signaling pathway: BMP4
hsa04520__18	5.12602983254322e-17	UP	8.3843400540775	1.47500919683747e-16	Adherens junction: SNAI2
hsa04015__82	5.54141903083876e-17	DOWN	-8.37516806988051	1.59209883164312e-16	Rap1 signaling pathway: ITGA2B
hsa05142__84	5.70560425061086e-17	DOWN	-8.37172857580664	1.63676799799966e-16	Chagas disease (American trypanosomiasis): NFKB1*
hsa04066__42	6.16725539163348e-17	DOWN	-8.36255659160964	1.76381626801816e-16	HIF-1 signaling pathway: HK1
hsa05161__227	6.16725539163348e-17	DOWN	-8.36255659160964	1.76381626801816e-16	Hepatitis B: MYD88*
hsa05205__434	6.66570621797486e-17	UP	8.35338460741265	1.90347446558887e-16	Proteoglycans in cancer: CASP3
hsa04390__77	6.73074152949615e-17	DOWN	-8.35223810938802	1.91912948921446e-16	Hippo signaling pathway: CCND1
hsa04210__50	6.8626952298949e-17	DOWN	-8.34994511333877	1.95378853590493e-16	Apoptosis: SPTA1
hsa05166__74	6.99719953070486e-17	DOWN	-8.34765211728953	1.98906776372079e-16	HTLV-I infection: NFKB1
hsa04630__28	8.9146330928476e-17	UP	8.31898966667392	2.5264850047452e-16	Jak-STAT signaling pathway: CCND1
hsa04662__32 51	8.9146330928476e-17	UP	8.31898966667392	2.5264850047452e-16	B cell receptor signaling pathway: BLNK GRB2
hsa04360__31	1.02058707468015e-16	DOWN	-8.30293869432918	2.88807697789759e-16	Axon guidance: CDC42*
hsa05200__201	1.03048583095257e-16	DOWN	-8.30179219630455	2.9117035734735e-16	Pathways in cancer: PDGFB
hsa04370__16	1.13482960159832e-16	DOWN	-8.29032721605831	3.20171895105593e-16	VEGF signaling pathway: HSPB1
hsa04910__43	1.16811677949299e-16	DOWN	-8.28688772198444	3.29069179710245e-16	Insulin signaling pathway: G6PC
hsa04915__28	1.22574748197629e-16	DOWN	-8.28115523186132	3.4478735308884e-16	Estrogen signaling pathway: KCNJ3
hsa04931__104	1.26166222412352e-16	UP	8.27771573778744	3.54359240527367e-16	Insulin resistance: C00369*
hsa05031__8	1.29856556038401e-16	DOWN	-8.27427624371357	3.63650660999634e-16	Amphetamine addiction: DRD1
hsa04510__20 69	1.29861412203701e-16	DOWN	-8.27427624371357	3.63650660999634e-16	Focal adhesion: VASP ACTB
hsa04724__65	1.36252699146051e-16	DOWN	-8.26854375359045	3.80980389427724e-16	Glutamatergic synapse: GRM3
hsa05166__53 146	1.38903586845997e-16	DOWN	-8.2662507575412	3.87815512159923e-16	HTLV-I infection: CREB1 CRTC2
hsa05130__26	1.51446288524114e-16	DOWN	-8.25593227531958	4.22207086256396e-16	Pathogenic Escherichia coli infection: CTNNB1
hsa04976__36	1.57372877830997e-16	UP	8.25134628322108	4.38079462880656e-16	Bile secretion: SLC10A1
hsa05231__21	1.66694778410251e-16	UP	8.24446729507334	4.63342438806008e-16	Choline metabolism in cancer: PCYT1A
hsa05205__188	1.73209446182836e-16	DOWN	-8.23988130297484	4.80739363925479e-16	Proteoglycans in cancer: TNF
hsa05211__22	1.96164526651656e-16	UP	8.22497682865473	5.43647707342864e-16	Renal cell carcinoma: TGFA
hsa05030__69	2.0187371895303e-16	DOWN	-8.22153733458085	5.58646123582833e-16	Cocaine addiction: PRKACA**
hsa04919__11	2.07746647967399e-16	DOWN	-8.21809784050698	5.7405286989815e-16	Thyroid hormone signaling pathway: CTNNB1
hsa05223__24	2.09741472520964e-16	DOWN	-8.21695134248236	5.78713989525537e-16	Non-small cell lung cancer: STK4
hsa04726__72	2.24243859752681e-16	DOWN	-8.20892585630999	6.17821425916843e-16	Serotonergic synapse: KCNJ3
hsa05212__34	2.44349996757833e-16	UP	8.19860737408837	6.72230810992633e-16	Pancreatic cancer: E2F1
hsa04810__29	2.49053819080357e-16	DOWN	-8.19631437803912	6.8416977492981e-16	Regulation of actin cytoskeleton: ACTN4
hsa05219__21	2.58730832294706e-16	UP	8.19172838594062	7.09715669900369e-16	Bladder cancer: RB1
hsa04024__115	2.79210097183626e-16	DOWN	-8.18255640174363	7.64775178728913e-16	cAMP signaling pathway: F2R
hsa04064__114	2.84574658368162e-16	DOWN	-8.18026340569438	7.7720317307235e-16	NF-kappa B signaling pathway: BCL2A1*
hsa04933__21	2.84574658368162e-16	DOWN	-8.18026340569438	7.7720317307235e-16	AGE-RAGE signaling pathway in diabetic complications: SMAD4
hsa05031__101	3.04162976945659e-16	DOWN	-8.17223791952201	8.29495259333662e-16	Amphetamine addiction: FOS*
hsa05205__256	3.12959370493555e-16	DOWN	-8.16879842544813	8.5224732921361e-16	Proteoglycans in cancer: ACTB
hsa04210__69	3.25078981361805e-16	DOWN	-8.16421243334964	8.83970196785575e-16	Apoptosis: PTPN13
hsa04360__145	3.28180456983356e-16	DOWN	-8.16306593532501	8.91114275537175e-16	Axon guidance: ABLIM3
hsa04066__88	3.3131109331866e-16	DOWN	-8.16191943730039	8.98316802807738e-16	HIF-1 signaling pathway: BCL2
hsa04920__40	3.37660930676318e-16	DOWN	-8.15962644125114	9.14214537090493e-16	Adipocytokine signaling pathway: PPARGC1A
hsa04727__8	3.40880679145369e-16	DOWN	-8.15847994322652	9.21604023185825e-16	GABAergic synapse: ADCY1
hsa04919__39	3.4413068326588e-16	DOWN	-8.15733344520189	9.29053956690502e-16	Thyroid hormone signaling pathway: ESR1
hsa04740__10	3.60844428275088e-16	DOWN	-8.15160095507877	9.72778595019929e-16	Olfactory transduction: ANO2
hsa04610__52	3.67751714317311e-16	DOWN	-8.14930795902952	9.89979185103479e-16	Complement and coagulation cascades: CPB2
hsa04976__34	3.96708034361723e-16	UP	8.14013597483253	1.06640113957894e-15	Bile secretion: SLCO1B1
hsa05214__35	4.08136387761955e-16	UP	8.13669648075865	1.09555467514959e-15	Glioma: E2F1
hsa04012__37 7	4.31975143686875e-16	DOWN	-8.12981749261091	1.15789057772844e-15	ErbB signaling pathway: ERBB3 ERBB3
hsa04068__14	4.70328095702143e-16	DOWN	-8.11949901038929	1.25889813650189e-15	FoxO signaling pathway: G6PC
hsa04910__57	5.2672777164272e-16	UP	8.1057410340938	1.40785417200095e-15	Insulin signaling pathway: GCK
hsa05205__318	5.73352876430022e-16	DOWN	-8.09542255187218	1.53029837331252e-15	Proteoglycans in cancer: HSPB2
hsa04022__63	5.89780564697413e-16	DOWN	-8.09198305779831	1.57191160434956e-15	cGMP-PKG signaling pathway: C00575
hsa04630__30	6.41897149382489e-16	UP	8.08166457557669	1.70839198822903e-15	Jak-STAT signaling pathway: CDKN1A
hsa04660__30	6.60257960343045e-16	DOWN	-8.07822508150281	1.75477327791313e-15	T cell receptor signaling pathway: CD40LG
hsa04728__54	6.72784996304368e-16	DOWN	-8.07593208545357	1.78554097183038e-15	Dopaminergic synapse: CAMK2A
hsa04210__70	6.98545738370709e-16	DOWN	-8.07134609335507	1.8512939949204e-15	Apoptosis: CFLAR*
hsa05211__49	7.05136308773754e-16	UP	8.07019959533045	1.86612834392378e-15	Renal cell carcinoma: TGFA*
hsa05161__100	8.04098420234267e-16	UP	8.05414862298571	2.12503647203965e-15	Hepatitis B: MMP9*
hsa04520__64	8.19309938297539e-16	DOWN	-8.05185562693646	2.16219575008578e-15	Adherens junction: CTNND1**
hsa05200__66	8.34804892859563e-16	DOWN	-8.04956263088721	2.19999774710115e-15	Pathways in cancer: CCND1
hsa03320__10	8.426602796497e-16	DOWN	-8.04841613286258	2.21758916731343e-15	PPAR signaling pathway: PLIN1
hsa03320__43	8.66665998408089e-16	DOWN	-8.04497663878871	2.27757400141091e-15	PPAR signaling pathway: ILK
hsa04750__44	8.83029682088358e-16	UP	8.04268364273946	2.31410428541705e-15	Inflammatory mediator regulation of TRP channels: TRPA1
hsa04750__63	8.83029682088358e-16	UP	8.04268364273946	2.31410428541705e-15	Inflammatory mediator regulation of TRP channels: TRPA1*
hsa04921__28	9.08181313690418e-16	UP	8.03924414866559	2.37670290866893e-15	Oxytocin signaling pathway: EEF2
hsa04064__113	9.25330641934335e-16	DOWN	-8.03695115261634	2.41485593915919e-15	NF-kappa B signaling pathway: CFLAR
hsa04151__100	9.25330641934335e-16	DOWN	-8.03695115261634	2.41485593915919e-15	PI3K-Akt signaling pathway: PRKCA
hsa04670__10	9.605919769502e-16	DOWN	-8.03236516051784	2.50340128250961e-15	Leukocyte transendothelial migration: BCAR1
hsa04010__15	1.02551214712047e-15	DOWN	-8.02433967434547	2.66888826099634e-15	MAPK signaling pathway: NFKB1
hsa05216__14	1.06453037909483e-15	UP	8.01975368224698	2.7666010820459e-15	Thyroid cancer: MAPK1*
hsa04071__65	1.07451124671029e-15	UP	8.01860718422235	2.78868319415556e-15	Sphingolipid signaling pathway: BAX*
hsa05133__96	1.13636168948005e-15	DOWN	-8.01172819607461	2.94513602004553e-15	Pertussis: IL1B
hsa05032__4	1.1470056328399e-15	DOWN	-8.01058169804998	2.96862752631705e-15	Morphine addiction: ADCY1
hsa04010__12	1.21296294957822e-15	UP	8.00370270990224	3.13071068991412e-15	MAPK signaling pathway: PLA2G4B
hsa05032__37	1.21296294957822e-15	DOWN	-8.00370270990224	3.13071068991412e-15	Morphine addiction: KCNJ3
hsa05134__69	1.34372963745899e-15	DOWN	-7.99109123163137	3.46346774867687e-15	Legionellosis: IL1B*
hsa05166__5	1.43407528188356e-15	UP	7.983065745459	3.69127048583455e-15	HTLV-I infection: SLC2A1
hsa05205__145	1.58826337977935e-15	DOWN	-7.97045426718813	4.0825538859171e-15	Proteoglycans in cancer: PXN
hsa05168__79	1.66365332779266e-15	UP	7.96472177706501	4.27049809142405e-15	Herpes simplex infection: EIF2S1
hsa04066__63	1.71056207394308e-15	DOWN	-7.96128228299114	4.37894569065265e-15	HIF-1 signaling pathway: TIMP1*
hsa04066__57	1.71056207394308e-15	DOWN	-7.96128228299114	4.37894569065265e-15	HIF-1 signaling pathway: TIMP1
hsa04921__57	1.85924437026413e-15	DOWN	-7.95096380076952	4.75308866901536e-15	Oxytocin signaling pathway: FOS
hsa04919__25	2.03940098678326e-15	UP	7.93949882052328	5.20656855185563e-15	Thyroid hormone signaling pathway: MTOR
hsa04064__129	2.71431463122244e-15	DOWN	-7.90395738175992	6.92021328638665e-15	NF-kappa B signaling pathway: PTGS2
hsa04066__64	2.73940516353742e-15	DOWN	-7.9028108837353	6.96528051730287e-15	HIF-1 signaling pathway: LTBR
hsa04151__4	2.73940516353742e-15	UP	7.9028108837353	6.96528051730287e-15	PI3K-Akt signaling pathway: RPS6
hsa05134__70	2.86832424708328e-15	DOWN	-7.89707839361218	7.28321791928308e-15	Legionellosis: IL6
hsa05010__47	2.8948159146628e-15	DOWN	-7.89593189558755	7.34056559197221e-15	Alzheimer's disease: C00533
hsa04622__45	3.08712456589497e-15	UP	7.88790640941518	7.81766450042675e-15	RIG-I-like receptor signaling pathway: MAPK14
hsa04520__7 68	3.11560477830059e-15	UP	7.88675991139056	7.87916740030527e-15	Adherens junction: CDH1 CTNNB1
hsa04621__23	3.17334352846893e-15	DOWN	-7.88446691534131	8.01439850805528e-15	NOD-like receptor signaling pathway: CASP1
hsa04071__24	3.32233992486485e-15	DOWN	-7.87873442521819	8.3794318373437e-15	Sphingolipid signaling pathway: PTEN
hsa04210__71	3.57518055730014e-15	DOWN	-7.86956244102119	8.99299098683664e-15	Apoptosis: GADD45G
hsa05162__23	3.57518055730014e-15	UP	7.86956244102119	8.99299098683664e-15	Measles: IRF3
hsa04710__7	3.91800291177237e-15	DOWN	-7.85809746077495	9.84214902569557e-15	Circadian rhythm: PER1
hsa04062__43	4.53497203571423e-15	DOWN	-7.83975349238096	1.13767856543485e-14	Chemokine signaling pathway: STAT1
hsa05223__14	4.79020051755838e-15	DOWN	-7.83287450423322	1.20010490299896e-14	Non-small cell lung cancer: CCND1
hsa05200__198	4.83409192916445e-15	DOWN	-7.83172800620859	1.20948851330226e-14	Pathways in cancer: BCL2L1*
hsa05140__62	5.54198823133807e-15	DOWN	-7.81453053583923	1.38476009131439e-14	Leishmaniasis: C00584
hsa04360__122	5.74739548360681e-15	DOWN	-7.80994454374073	1.43417743873801e-14	Axon guidance: CFL1**
hsa05321__81	5.85289118667334e-15	DOWN	-7.80765154769148	1.45856532357549e-14	Inflammatory bowel disease (IBD): IL13
hsa04970__12	6.12444020415486e-15	UP	7.80191905756836	1.52421498590821e-14	Salivary secretion: BEST2
hsa04151__109	6.58660342526e-15	UP	7.79274707337136	1.63706717408248e-14	PI3K-Akt signaling pathway: RXRA
hsa04064__50	6.76837512247455e-15	DOWN	-7.78930757929749	1.68002336263272e-14	NF-kappa B signaling pathway: NFKBIA*
hsa05164__53	6.89229005072912e-15	DOWN	-7.78701458324824	1.70852414318206e-14	Influenza A: MAPK14
hsa04920__37	7.54615004054722e-15	UP	7.775549603002	1.86814439080214e-14	Adipocytokine signaling pathway: IRS1
hsa03320__64	7.68406565775577e-15	DOWN	-7.77325660695275	1.89978412775304e-14	PPAR signaling pathway: APOA5
hsa04662__24	7.82446134213131e-15	DOWN	-7.7709636109035	1.92941769840745e-14	B cell receptor signaling pathway: FOS
hsa04950__11	7.82446134213131e-15	UP	7.7709636109035	1.92941769840745e-14	Maturity onset diabetes of the young: HNF4G
hsa04151__37	7.89560288189831e-15	DOWN	-7.76981711287888	1.94440862583053e-14	PI3K-Akt signaling pathway: G6PC
hsa05205__34	8.11286905924254e-15	DOWN	-7.76637761880501	1.99529855527706e-14	Proteoglycans in cancer: SLC9A1
hsa04750__60	8.26075595158203e-15	UP	7.76408462275576	2.02901443568923e-14	Inflammatory mediator regulation of TRP channels: TRPV3
hsa04340__40	8.41173317820806e-15	UP	7.76179162670651	2.06340034488942e-14	Hedgehog signaling pathway: SUFU
hsa04350__27	8.56520231870959e-15	DOWN	-7.75949863065726	2.09830706086771e-14	TGF-beta signaling pathway: ACVR2A*
hsa05110__50	1.31978947863187e-14	DOWN	-7.70446672547529	3.22901618535063e-14	Vibrio cholerae infection: ACTB
hsa04550__66	1.48302208967403e-14	DOWN	-7.68956225115518	3.62366515799415e-14	Signaling pathways regulating pluripotency of stem cells: MYC
hsa04620__40	1.52341679312633e-14	DOWN	-7.68612275708131	3.71271096534938e-14	Toll-like receptor signaling pathway: CCL5
hsa05200__217	1.52341679312633e-14	UP	7.68612275708131	3.71271096534938e-14	Pathways in cancer: E2F1*
hsa04742__31	1.57896448415293e-14	DOWN	-7.68153676498281	3.84310138047066e-14	Taste transduction: C00076*
hsa05213__29	1.63650369975455e-14	DOWN	-7.67695077288431	3.97799540988203e-14	Endometrial cancer: CCND1
hsa05200__96	1.69610458760472e-14	UP	7.67236478078581	4.11754589161405e-14	Pathways in cancer: C00416
hsa04211__23	2.12005257868704e-14	DOWN	-7.64370233017021	5.14010167142317e-14	Longevity regulating pathway - mammal: SOD2
hsa05162__25 70	2.13902118607768e-14	DOWN	-7.64255583214558	5.17940825855665e-14	Measles: IFNAR1 GNB2L1
hsa04650__16	2.23639713808983e-14	DOWN	-7.63682334202246	5.40822422454413e-14	Natural killer cell mediated cytotoxicity: PRKCA
hsa04919__103	2.38008629796264e-14	DOWN	-7.62879785585009	5.74830611037506e-14	Thyroid hormone signaling pathway: CCND1
hsa05164__24	2.67143006082573e-14	DOWN	-7.61389338152997	6.44366763066952e-14	Influenza A: IRF7
hsa04210__62	2.69524129784155e-14	UP	7.61274688350535	6.49276717774907e-14	Apoptosis: TP53AIP1
hsa05152__98	2.74349172426982e-14	UP	7.6104538874561	6.6005389883521e-14	Tuberculosis: IL23A
hsa04550__17	2.79259148119745e-14	DOWN	-7.60816089140685	6.71007595034528e-14	Signaling pathways regulating pluripotency of stem cells: AKT3
hsa04510__47	2.84255525630463e-14	DOWN	-7.6058678953576	6.80402716763874e-14	Focal adhesion: CCND1
hsa04917__31	2.84255525630463e-14	DOWN	-7.6058678953576	6.80402716763874e-14	Prolactin signaling pathway: GALT
hsa04931__87	2.84255525630463e-14	DOWN	-7.6058678953576	6.80402716763874e-14	Insulin resistance: C00031*
hsa04910__20	2.8678658086296e-14	UP	7.60472139733298	6.85587767737279e-14	Insulin signaling pathway: PKLR
hsa04152__68	2.89339798656786e-14	DOWN	-7.60357489930835	6.90812556132276e-14	AMPK signaling pathway: PPARGC1A**
hsa04068__13	2.91915369687472e-14	DOWN	-7.60242840128373	6.95195157975614e-14	FoxO signaling pathway: PCK1
hsa04115__58	2.91915369687472e-14	UP	7.60242840128373	6.95195157975614e-14	p53 signaling pathway: CASP3
hsa03320__32	3.90797452767989e-14	DOWN	-7.56459396647113	9.29504321203863e-14	PPAR signaling pathway: FABP3
hsa05200__192	4.23056777759771e-14	DOWN	-7.55427548424951	1.00496041139142e-13	Pathways in cancer: PTGS2
hsa04670__76	4.53920662382445e-14	DOWN	-7.54510350005252	1.07691530885936e-13	Leukocyte transendothelial migration: CDC42
hsa04064__95	4.82735339107429e-14	DOWN	-7.53707801388015	1.14383316794812e-13	NF-kappa B signaling pathway: BCL2L1**
hsa05200__197	5.08859488533819e-14	DOWN	-7.5301990257324	1.20421533873431e-13	Pathways in cancer: CCND1**
hsa04910__14	5.22437912907522e-14	UP	7.52675953165853	1.23169490383091e-13	Insulin signaling pathway: C00369
hsa05160__58	5.22437912907522e-14	UP	7.52675953165853	1.23169490383091e-13	Hepatitis C: EIF3E
hsa05164__47	5.22437912907522e-14	DOWN	-7.52675953165853	1.23169490383091e-13	Influenza A: CIITA
hsa03320__37	5.80405296416345e-14	DOWN	-7.51300155536304	1.36493310634082e-13	PPAR signaling pathway: HMGCS2
hsa04152__103	5.80405296416345e-14	UP	7.51300155536304	1.36493310634082e-13	AMPK signaling pathway: ULK1
hsa04340__31	6.11715346453358e-14	UP	7.50612256721529	1.43676641998232e-13	Hedgehog signaling pathway: GLI1***
hsa05160__7	6.17092703978313e-14	UP	7.50497606919067	1.44758700471317e-13	Hepatitis C: IRF3
hsa04810__26 80	6.22516526717164e-14	DOWN	-7.50382957116604	1.4584894684558e-13	Regulation of actin cytoskeleton: PFN3 ACTB
hsa04360__3	7.09725806350802e-14	DOWN	-7.48663210079668	1.66074071000393e-13	Axon guidance: GNAI1
hsa05321__152	7.61038753708534e-14	UP	7.47746011659968	1.77859678882877e-13	Inflammatory bowel disease (IBD): FOXP3*
hsa04022__59	8.15994074889741e-14	DOWN	-7.46828813240269	1.90466194623332e-13	cGMP-PKG signaling pathway: NPPB
hsa05012__71	8.74845367367819e-14	DOWN	-7.45911614820569	2.03949683037733e-13	Parkinson's disease: PRKACA*
hsa04950__20	9.62628052021715e-14	UP	7.44650466993483	2.24136073079158e-13	Maturity onset diabetes of the young: NKX6-1
hsa04390__60	9.71024852886507e-14	DOWN	-7.4453581719102	2.25811348833384e-13	Hippo signaling pathway: CTGF*
hsa05212__54	1.04084195230028e-13	UP	7.43618618771321	2.41748087561463e-13	Pancreatic cancer: C00416
hsa05100__55	1.15491247344834e-13	DOWN	-7.42242821141772	2.67911177482646e-13	Bacterial invasion of epithelial cells: ACTB*
hsa04915__30	1.16495490010087e-13	DOWN	-7.42128171339309	2.69575154838612e-13	Estrogen signaling pathway: CREB3*
hsa05164__19	1.16495490010087e-13	DOWN	-7.42128171339309	2.69575154838612e-13	Influenza A: NFKB1
hsa05032__31	1.25928552498022e-13	UP	7.41096323117147	2.90330981771514e-13	Morphine addiction: GABRR3
hsa05032__33	1.25928552498022e-13	UP	7.41096323117147	2.90330981771514e-13	Morphine addiction: GABRR3*
hsa05032__55	1.25928552498022e-13	UP	7.41096323117147	2.90330981771514e-13	Morphine addiction: GABRR3**
hsa03320__25	1.34940991817538e-13	UP	7.40179124697448	3.10347764535071e-13	PPAR signaling pathway: EHHADH
hsa04068__55	1.34940991817538e-13	DOWN	-7.40179124697448	3.10347764535071e-13	FoxO signaling pathway: ATM
hsa04310__33	1.38481582119578e-13	UP	7.39835175290061	3.18101335944604e-13	Wnt signaling pathway: CCND1
hsa04971__49	1.4334470270473e-13	DOWN	-7.39376576080211	3.28870203152855e-13	Gastric acid secretion: KCNJ1
hsa03320__33	1.64531989766509e-13	DOWN	-7.37542179240812	3.76559815799355e-13	PPAR signaling pathway: CYP7A1
hsa04520__44 52 45	1.64531989766509e-13	DOWN	-7.37542179240812	3.76559815799355e-13	Adherens junction: ACTB ACTN4 CTNNA1
hsa04666__30 44	1.73246337302263e-13	DOWN	-7.36854280426037	3.96021736971962e-13	Fc gamma R-mediated phagocytosis: C04637 GSN
hsa05034__61	1.80853416553505e-13	DOWN	-7.36281031413725	4.12908347149498e-13	Alcoholism: CRH
hsa04620__39	1.855741905545e-13	DOWN	-7.35937082006338	4.23172213655226e-13	Toll-like receptor signaling pathway: IL6
hsa04650__14	2.0925448640485e-13	DOWN	-7.34331984771864	4.76592945399653e-13	Natural killer cell mediated cytotoxicity: CSF2
hsa04261__8 38	2.11055212577599e-13	DOWN	-7.34217334969401	4.80112281396258e-13	Adrenergic signaling in cardiomyocytes: ATP2A2 PLN
hsa04210__83	2.20289697580756e-13	DOWN	-7.33644085957089	5.00513109739105e-13	Apoptosis: TP53*
hsa04621__42	2.31896070348666e-13	DOWN	-7.32956187142315	5.26247241769497e-13	NOD-like receptor signaling pathway: MAPK8
hsa05223__21	2.33888009889557e-13	DOWN	-7.32841537339852	5.30127346902868e-13	Non-small cell lung cancer: FOXO3*
hsa04972__51	2.70439276731754e-13	UP	7.30892490697991	6.12235422866225e-13	Pancreatic secretion: CLCA1
hsa04152__94	2.72755949712798e-13	DOWN	-7.30777840895529	6.16736978953487e-13	AMPK signaling pathway: MLYCD
hsa04922__51	2.82219155918763e-13	DOWN	-7.30319241685679	6.37367540830956e-13	Glucagon signaling pathway: G6PC
hsa04068__44	2.92004648530663e-13	DOWN	-7.29860642475829	6.58675551727629e-13	FoxO signaling pathway: CDKN1B
hsa05200__195	3.04706160028216e-13	DOWN	-7.29287393463517	6.86502247833355e-13	Pathways in cancer: BIRC8
hsa04666__27	3.17949886005223e-13	DOWN	-7.28714144451205	7.14626597851451e-13	Fc gamma R-mediated phagocytosis: ARPC5
hsa05160__8	3.17949886005223e-13	DOWN	-7.28714144451205	7.14626597851451e-13	Hepatitis C: NFKB1
hsa04064__2	3.28950479821681e-13	DOWN	-7.28255545241355	7.37587054397301e-13	NF-kappa B signaling pathway: BCL2L1
hsa04151__110	3.28950479821681e-13	UP	7.28255545241355	7.37587054397301e-13	PI3K-Akt signaling pathway: BCL2**
hsa05014__5	3.46155682639451e-13	UP	7.27567646426581	7.75240199856411e-13	Amyotrophic lateral sclerosis (ALS): TOMM40
hsa04670__55	3.55086663234783e-13	DOWN	-7.27223697019193	7.94295047878758e-13	Leukocyte transendothelial migration: RAC2
hsa05152__23	3.61165966284695e-13	UP	7.26994397414268	8.06933235016578e-13	Tuberculosis: PPP3CA
hsa05169__103	3.73632805616222e-13	DOWN	-7.26535798204419	8.33795774053304e-13	Epstein-Barr virus infection: NFKB1*
hsa04211__50	3.86521988877838e-13	DOWN	-7.26077198994569	8.61535963346926e-13	Longevity regulating pathway - mammal: PPARGC1A*
hsa04360__111	4.35166769295167e-13	UP	7.24472101760095	9.68813222163056e-13	Axon guidance: RHOA***
hsa04151__101	4.50136811714821e-13	DOWN	-7.24013502550245	1.00095511149367e-12	PI3K-Akt signaling pathway: PKN3
hsa05160__37	5.08823936998187e-13	DOWN	-7.22293755513309	1.13011841326193e-12	Hepatitis C: STAT3
hsa04068__41	5.51174179140068e-13	DOWN	-7.21261907291147	1.22273469020565e-12	FoxO signaling pathway: CDKN2B
hsa04520__69	5.6053530598321e-13	DOWN	-7.21032607686222	1.24203518861138e-12	Adherens junction: IQGAP1**
hsa04390__52	5.65274227375172e-13	DOWN	-7.2091795788376	1.25106039250642e-12	Hippo signaling pathway: ITGB2
hsa04210__3	6.20069687761894e-13	DOWN	-7.19656810056673	1.37071875682894e-12	Apoptosis: BCL2L1
hsa04068__48	6.4666938081301e-13	DOWN	-7.19083561044361	1.42783991368701e-12	FoxO signaling pathway: FASLG
hsa05168__92 93	6.57620117145238e-13	DOWN	-7.18854261439436	1.45031478886843e-12	Herpes simplex infection: IRF9 STAT1
hsa04725__64	6.80070510888459e-13	DOWN	-7.18395662229586	1.49806856970623e-12	Cholinergic synapse: KCNJ3
hsa04022__58	7.0919373363719e-13	DOWN	-7.17822413217274	1.56039230152726e-12	cGMP-PKG signaling pathway: MYH7
hsa05200__220	7.52032581353948e-13	DOWN	-7.17019864600037	1.65271253843751e-12	Pathways in cancer: CSF1R*
hsa04976__59	7.647319873492e-13	DOWN	-7.16790564995112	1.67865818251069e-12	Bile secretion: ABCB4
hsa04740__13	7.77641828210719e-13	DOWN	-7.16561265390187	1.70500466185291e-12	Olfactory transduction: CNGA3
hsa05168__10	8.38433173729625e-13	DOWN	-7.15529417168025	1.83614910657106e-12	Herpes simplex infection: FOS
hsa04360__131	8.59715265784754e-13	DOWN	-7.15185467760638	1.88056459186211e-12	Axon guidance: RAC1****
hsa05133__94	9.26793350408826e-13	DOWN	-7.14153619538476	2.02493570397463e-12	Pertussis: IL12A
hsa04010__78	9.66251314798546e-13	DOWN	-7.13580370526164	2.1086947973362e-12	MAPK signaling pathway: MAP3K4
hsa05205__77	1.00731229876213e-12	DOWN	-7.13007121513852	2.19575383918103e-12	Proteoglycans in cancer: MIR21
hsa04668__138	1.18964053266452e-12	DOWN	-7.10714125464603	2.59019068467745e-12	TNF signaling pathway: NFKB1*
hsa04012__3	1.26079400157326e-12	UP	7.09911576847366	2.73876523578746e-12	ErbB signaling pathway: ELK1
hsa04068__53	1.26079400157326e-12	DOWN	-7.09911576847366	2.73876523578746e-12	FoxO signaling pathway: SOD2
hsa04360__11	1.27129384857796e-12	DOWN	-7.09796927044904	2.75838468992838e-12	Axon guidance: NFATC2
hsa04620__34	1.3250937130624e-12	DOWN	-7.09223678032592	2.87180056152739e-12	Toll-like receptor signaling pathway: IL1B
hsa04622__6	1.3584393522557e-12	DOWN	-7.08879728625204	2.94067689272863e-12	RIG-I-like receptor signaling pathway: NFKB1
hsa04666__23	1.50025276874559e-12	DOWN	-7.07503930995655	3.24020109479651e-12	Fc gamma R-mediated phagocytosis: RPS6KB1
hsa05215__14	1.50025276874559e-12	DOWN	-7.07503930995655	3.24020109479651e-12	Prostate cancer: CCND1
hsa04970__28	1.61603294508324e-12	DOWN	-7.06472082773493	3.486252472803e-12	Salivary secretion: AQP5
hsa04915__3 11	1.65656273930959e-12	DOWN	-7.06128133366106	3.56142035144475e-12	Estrogen signaling pathway: ESR1 C00951
hsa04915__12 14	1.65656273930959e-12	DOWN	-7.06128133366106	3.56142035144475e-12	Estrogen signaling pathway: ESR1 FOS
hsa04915__12 13	1.65656273930959e-12	DOWN	-7.06128133366106	3.56142035144475e-12	Estrogen signaling pathway: ESR1 C00951*
hsa04921__48	1.75500876078448e-12	DOWN	-7.05325584748869	3.76875595601604e-12	Oxytocin signaling pathway: PRKAG2
hsa04340__52	1.9856889716511e-12	UP	7.03605837711933	4.25925750882695e-12	Hedgehog signaling pathway: BCL2*
hsa04913__19	2.03527208544287e-12	UP	7.03261888304545	4.36063426288158e-12	Ovarian steroidogenesis: STAR
hsa04024__9 95	2.12062244118807e-12	DOWN	-7.02688639292233	4.53832524714395e-12	cAMP signaling pathway: ATP1B4 FXYD1
hsa05134__68	2.17350754917693e-12	DOWN	-7.02344689884846	4.64621238328037e-12	Legionellosis: TNF
hsa05016__60	2.20948072444737e-12	UP	7.02115390279921	4.71238851445699e-12	Huntington's disease: CASP3*
hsa05134__35	2.20948072444737e-12	UP	7.02115390279921	4.71238851445699e-12	Legionellosis: CASP3
hsa04010__118	2.47816884386862e-12	UP	7.00510293045447	5.27945494062261e-12	MAPK signaling pathway: JUN
hsa05164__90	2.53978378198992e-12	DOWN	-7.0016634363806	5.40459085657878e-12	Influenza A: MAPK1
hsa04727__17 37	2.77882834487704e-12	UP	6.98905195810973	5.9065819683529e-12	GABAergic synapse: GABRA1 GPHN
hsa03320__39	2.9183764165324e-12	UP	6.98217296996198	6.19619128436653e-12	PPAR signaling pathway: MMP1
hsa04068__40	3.46306781449372e-12	DOWN	-6.95809651144487	7.34436165173105e-12	FoxO signaling pathway: CCND1
hsa04742__23 45	3.54846325336394e-12	DOWN	-6.954657017371	7.51698134506296e-12	Taste transduction: PKD1L3 PKD2L1
hsa05321__83	3.72594677030665e-12	DOWN	-6.94777802922326	7.88406979888086e-12	Inflammatory bowel disease (IBD): IL2
hsa05200__210	4.20818875216034e-12	DOWN	-6.93058055885389	8.89447318932428e-12	Pathways in cancer: MMP1
hsa05200__121 122	4.79003558350077e-12	DOWN	-6.9122365904599	1.01015452989876e-11	Pathways in cancer: SMAD2 SMAD4
hsa05212__38 39	4.79003558350077e-12	DOWN	-6.9122365904599	1.01015452989876e-11	Pancreatic cancer: SMAD2 SMAD4
hsa04971__39	4.86809558379496e-12	DOWN	-6.90994359441065	1.02546542622766e-11	Gastric acid secretion: EZR
hsa04068__43	4.90759183509309e-12	DOWN	-6.90879709638603	1.0326276660851e-11	FoxO signaling pathway: CDKN1A
hsa04014__37	5.1512508769684e-12	DOWN	-6.90191810823828	1.08268460825768e-11	Ras signaling pathway: FASLG
hsa04072__57	5.53912657943319e-12	UP	6.89159962601667	1.16290713326871e-11	Phospholipase D signaling pathway: C06124
hsa04710__23	5.62913262592903e-12	UP	6.88930662996742	1.18048439778132e-11	Circadian rhythm: BHLHE41
hsa04922__50	5.67467163978017e-12	DOWN	-6.88816013194279	1.18870769355038e-11	Glucagon signaling pathway: PCK1
hsa04022__9	6.71886192534809e-12	DOWN	-6.86408367342568	1.40587322469143e-11	cGMP-PKG signaling pathway: ITPR1
hsa05205__270	8.5439776713631e-12	DOWN	-6.82968873268695	1.78577686813029e-11	Proteoglycans in cancer: MAPK1****
hsa04668__40	8.68160077340988e-12	DOWN	-6.8273957366377	1.81252531702635e-11	TNF signaling pathway: JUN
hsa04610__11	9.7853466068632e-12	UP	6.81019826626834	2.04069547994406e-11	Complement and coagulation cascades: F2R
hsa04961__20	1.01020359278112e-11	UP	6.80561227416984	2.10440415835446e-11	Endocrine and other factor-regulated calcium reabsorption: CALB1*
hsa04917__71	1.01829517274801e-11	DOWN	-6.80446577614522	2.11891099622759e-11	Prolactin signaling pathway: CCND1*
hsa05215__43	1.03462354860049e-11	DOWN	-6.80217278009597	2.15050624758885e-11	Prostate cancer: C05981
hsa04068__96	1.09389052575812e-11	DOWN	-6.7941472939236	2.26867582549615e-11	FoxO signaling pathway: CCNG2
hsa05221__27	1.09389052575812e-11	DOWN	-6.7941472939236	2.26867582549615e-11	Acute myeloid leukemia: PIM2
hsa05162__27 28	1.10262195730556e-11	DOWN	-6.79300079589898	2.28426312875098e-11	Measles: STAT1 IRF9
hsa04152__60	1.12922791289996e-11	UP	6.7895613018251	2.33680533958043e-11	AMPK signaling pathway: EEF2
hsa04722__34	1.21287565117888e-11	UP	6.77924281960348	2.50714339776141e-11	Neurotrophin signaling pathway: GSK3B
hsa05016__52	1.22253633427689e-11	UP	6.77809632157886	2.5243360133036e-11	Huntington's disease: CASP3
hsa04611__92	1.26193843709585e-11	DOWN	-6.77351032948036	2.60283460296719e-11	Platelet activation: RHOA*
hsa04520__17	1.28210326576985e-11	DOWN	-6.77121733343111	2.64152635568152e-11	Adherens junction: SNAI1
hsa04390__74	1.33390624107771e-11	DOWN	-6.76548484330799	2.74524625080506e-11	Hippo signaling pathway: AXIN1
hsa04380__38	1.35519660592431e-11	DOWN	-6.76319184725874	2.78601140320763e-11	Osteoclast differentiation: FOS
hsa05016__55	1.36596624057424e-11	DOWN	-6.76204534923412	2.80508258583497e-11	Huntington's disease: TGM2
hsa04930__8	1.37681968600945e-11	UP	6.76089885120949	2.82428405023117e-11	Type II diabetes mellitus: C00022
hsa04068__66	1.42108440390522e-11	DOWN	-6.756312859111	2.91190577419618e-11	FoxO signaling pathway: BNIP3
hsa04621__4 7 8	1.4437364384329e-11	UP	6.75401986306175	2.95509887561593e-11	NOD-like receptor signaling pathway: IKBKG CHUK IKBKB
hsa04390__12	1.57478816351309e-11	DOWN	-6.74140838479088	3.21983347033853e-11	Hippo signaling pathway: CTGF
hsa05321__74	1.70399066995505e-11	DOWN	-6.72994340454464	3.48021572700603e-11	Inflammatory bowel disease (IBD): IL5
hsa04722__37	1.71746794977083e-11	DOWN	-6.72879690652001	3.50393298330009e-11	Neurotrophin signaling pathway: NFKB1
hsa05205__352	2.27859194138471e-11	DOWN	-6.68752297763354	4.6388725733738e-11	Proteoglycans in cancer: ITGA5*
hsa05145__9	2.27870110975201e-11	UP	6.68752297763354	4.6388725733738e-11	Toxoplasmosis: MAPK1
hsa04915__66	2.296614418659e-11	DOWN	-6.68637647960892	4.67027975396132e-11	Estrogen signaling pathway: AKT3*
hsa04071__68	2.44497109892029e-11	DOWN	-6.67720449541192	4.96659534580673e-11	Sphingolipid signaling pathway: NFKB1
hsa04340__51	2.46416291542911e-11	UP	6.6760579973873	5.00017507353272e-11	Hedgehog signaling pathway: CCND1*
hsa04270__46	2.52262748217322e-11	UP	6.67261850331342	5.11328698921626e-11	Vascular smooth muscle contraction: ITPR1*
hsa04064__115	2.60269671292598e-11	DOWN	-6.66803251121493	5.26989991765939e-11	NF-kappa B signaling pathway: XIAP
hsa04064__55	2.66437604040449e-11	DOWN	-6.66459301714105	5.38898017214213e-11	NF-kappa B signaling pathway: CXCL12
hsa04921__23	2.99488238810645e-11	DOWN	-6.64739554677169	6.05095054543227e-11	Oxytocin signaling pathway: C00219
hsa04670__86	3.41804337128486e-11	DOWN	-6.62790508035308	6.89849999424732e-11	Leukocyte transendothelial migration: ACTB
hsa05223__7	3.63697642176742e-11	DOWN	-6.61873309615608	7.33248787178217e-11	Non-small cell lung cancer: FOXO3
hsa05231__34	3.66528409544164e-11	UP	6.61758659813146	7.38163860164506e-11	Choline metabolism in cancer: PLD1
hsa04922__70	4.11668726772681e-11	UP	6.60038912776209	8.28185800434548e-11	Glucagon signaling pathway: PFKFB1
hsa04211__38	4.24597421150233e-11	UP	6.5958031356636	8.53281876300842e-11	Longevity regulating pathway - mammal: BAX
hsa05164__41 42	4.51657742319775e-11	DOWN	-6.5866311514666	9.05725611332826e-11	Influenza A: STAT1 IRF9
hsa05164__65 66	4.51657742319775e-11	DOWN	-6.5866311514666	9.05725611332826e-11	Influenza A: DNAJC3 HSPA1A
hsa04151__35	4.55156716862513e-11	DOWN	-6.58548465344198	9.11769158832261e-11	PI3K-Akt signaling pathway: CCND1
hsa04210__10	4.76714314765682e-11	DOWN	-6.57860566529423	9.53936312507686e-11	Apoptosis: BIRC2
hsa04360__40 139	5.47556725185838e-11	DOWN	-6.55796870085099	1.09453094321722e-10	Axon guidance: UNC5D DCC
hsa04722__73 77	5.9581447851966e-11	UP	6.54535722258013	1.18846645980726e-10	Neurotrophin signaling pathway: NGFRAP1 YWHAE
hsa05160__66	5.9581447851966e-11	UP	6.54535722258013	1.18846645980726e-10	Hepatitis C: GSK3B
hsa04917__75	6.19102125214529e-11	UP	6.53962473245701	1.23360858247943e-10	Prolactin signaling pathway: CCND1**
hsa05012__57	6.23865351135918e-11	UP	6.53847823443238	1.24178283345804e-10	Parkinson's disease: CASP3
hsa04921__67	6.89146279656584e-11	DOWN	-6.52357376011227	1.3702707507669e-10	Oxytocin signaling pathway: RYR1
hsa05014__13	6.9443589356619e-11	UP	6.52242726208764	1.37932879916583e-10	Amyotrophic lateral sclerosis (ALS): CASP3
hsa04213__53	7.32591234216258e-11	DOWN	-6.51440177591527	1.45357859460649e-10	Longevity regulating pathway - multiple species: SOD1
hsa05166__26	7.4386427751075e-11	DOWN	-6.51210877986602	1.47438921671171e-10	HTLV-I infection: NFATC1
hsa04012__43	7.66921593209154e-11	UP	6.50752278776752	1.51848859182297e-10	ErbB signaling pathway: PTK2
hsa04910__42	8.53259150630773e-11	DOWN	-6.49147181542279	1.68765678319497e-10	Insulin signaling pathway: PCK1
hsa05200__223	9.78333920278354e-11	DOWN	-6.47083485097955	1.93097629853259e-10	Pathways in cancer: CCND1****
hsa05221__17	9.78333920278354e-11	DOWN	-6.47083485097955	1.93097629853259e-10	Acute myeloid leukemia: CCND1
hsa04068__51	1.02387968058791e-10	DOWN	-6.4639558628318	2.01663513608457e-10	FoxO signaling pathway: BCL6
hsa04068__56	1.02387968058791e-10	DOWN	-6.4639558628318	2.01663513608457e-10	FoxO signaling pathway: BCL6*
hsa04310__35	1.06341243262384e-10	UP	6.45822337270868	2.0923057182201e-10	Wnt signaling pathway: JUN
hsa04064__51	1.07149615958392e-10	DOWN	-6.45707687468406	2.1060055270483e-10	NF-kappa B signaling pathway: TNFAIP3
hsa04950__15	1.09610944982026e-10	UP	6.45363738061018	2.15213130220717e-10	Maturity onset diabetes of the young: IAPP
hsa04064__4	1.30408380849428e-10	DOWN	-6.42726792604382	2.55780112334108e-10	NF-kappa B signaling pathway: BIRC2
hsa04071__69	1.31395139781717e-10	DOWN	-6.4261214280192	2.57446785870539e-10	Sphingolipid signaling pathway: RAC1
hsa04915__40	1.36439435260354e-10	DOWN	-6.42038893789608	2.67051769639797e-10	Estrogen signaling pathway: CREB3**
hsa05221__13	1.41672826172048e-10	DOWN	-6.41465644777296	2.77006493628802e-10	Acute myeloid leukemia: NFKB1
hsa05162__44	1.43820668977125e-10	DOWN	-6.41236345172371	2.80913759883595e-10	Measles: PRKCQ
hsa05200__184	1.44906491046134e-10	UP	6.41121695369908	2.82740702674647e-10	Pathways in cancer: GLI1
hsa05162__105	1.47102222714368e-10	UP	6.40892395764983	2.86727257759645e-10	Measles: GSK3B
hsa05205__233 234	1.56214904871867e-10	DOWN	-6.39975197345284	3.04173892491438e-10	Proteoglycans in cancer: ITGA2 C00925
hsa05219__27	1.59772475380758e-10	DOWN	-6.39631247937897	3.10778966087416e-10	Bladder cancer: RPS6KA5
hsa04151__51	1.62188043240486e-10	DOWN	-6.39401948332972	3.15151327041234e-10	PI3K-Akt signaling pathway: NOS3
hsa05210__9 11	1.63409172758802e-10	DOWN	-6.39287298530509	3.1719611117127e-10	Colorectal cancer: SMAD2 SMAD4
hsa05152__82	1.76125273790783e-10	DOWN	-6.38140800505885	3.4117462830194e-10	Tuberculosis: IL6
hsa05217__22	1.76125273790783e-10	DOWN	-6.38140800505885	3.4117462830194e-10	Basal cell carcinoma: LEF1
hsa05010__50	1.80125153507075e-10	DOWN	-6.37796851098498	3.48563505087326e-10	Alzheimer's disease: ERN1
hsa04961__17	1.82840903900315e-10	UP	6.37567551493573	3.53454792622111e-10	Endocrine and other factor-regulated calcium reabsorption: CALB1
hsa04612__18	1.85596644925334e-10	DOWN	-6.37338251888648	3.5841325366362e-10	Antigen processing and presentation: KIR2DS2
hsa05210__39	1.92664744309407e-10	UP	6.36765002876336	3.71680754165684e-10	Colorectal cancer: BAD
hsa04919__101	1.97031119877134e-10	DOWN	-6.36421053468949	3.79714332563215e-10	Thyroid hormone signaling pathway: NOTCH1
hsa04724__5 71	1.99995588806265e-10	UP	6.36191753864024	3.83852616309471e-10	Glutamatergic synapse: GRIN3A DLG4
hsa05031__11	1.99995588806265e-10	UP	6.36191753864024	3.83852616309471e-10	Amphetamine addiction: GRIN3A
hsa05031__54	1.99995588806265e-10	UP	6.36191753864024	3.83852616309471e-10	Amphetamine addiction: GRIN3A*
hsa05152__120	1.99995588806265e-10	DOWN	-6.36191753864024	3.83852616309471e-10	Tuberculosis: TGFB1
hsa05200__216	2.01494118810232e-10	DOWN	-6.36077104061561	3.86334131882067e-10	Pathways in cancer: IL6
hsa04722__70	2.12295330115357e-10	DOWN	-6.35274555444324	4.06628873890679e-10	Neurotrophin signaling pathway: ZNF274
hsa04950__31	2.22002059514006e-10	UP	6.3458665662955	4.2478805481346e-10	Maturity onset diabetes of the young: NKX6-1*
hsa04064__131	2.30421030608713e-10	DOWN	-6.34013407617238	4.40448745181864e-10	NF-kappa B signaling pathway: CCL4L1
hsa05205__109	2.4093606903116e-10	DOWN	-6.33325508802463	4.60080156208892e-10	Proteoglycans in cancer: SMAD2
hsa04921__41	2.5191928992281e-10	DOWN	-6.32637609987689	4.80564818035492e-10	Oxytocin signaling pathway: PTGS2
hsa04910__12	2.77420322131621e-10	UP	6.31147162555677	5.28674224427297e-10	Insulin signaling pathway: FASN
hsa05161__44	2.81560993263947e-10	UP	6.30917862950752	5.36021384339367e-10	Hepatitis B: CXCL8
hsa05152__77	2.90024190062211e-10	DOWN	-6.30459263740902	5.51574345270137e-10	Tuberculosis: IL12A
hsa05216__12	2.99198002487339e-10	UP	6.29771364926128	5.6844595214733e-10	Thyroid cancer: CDH1
hsa04976__37	3.24026617459807e-10	DOWN	-6.28739516703966	6.14380327922176e-10	Bile secretion: ABCB11
hsa05205__238	3.24029220314463e-10	UP	6.28739516703966	6.14380327922176e-10	Proteoglycans in cancer: ITGAV*
hsa05010__49	3.33737858310842e-10	UP	6.28280917494116	6.32150640893217e-10	Alzheimer's disease: EIF2AK3
hsa03320__47	3.43728741812741e-10	UP	6.27822318284267	6.50419240549991e-10	PPAR signaling pathway: PLTP
hsa05220__50	3.48833098802243e-10	UP	6.27593018679342	6.59413875904844e-10	Chronic myeloid leukemia: MAPK1
hsa04115__19	3.7548568317552e-10	UP	6.26446520654717	7.08371083018877e-10	p53 signaling pathway: RFWD2
hsa04670__54	3.7548568317552e-10	DOWN	-6.26446520654717	7.08371083018877e-10	Leukocyte transendothelial migration: RAC1*
hsa04919__91	3.78257791215874e-10	UP	6.26331870852255	7.12885044829114e-10	Thyroid hormone signaling pathway: PFKP
hsa04620__46	4.01165693698489e-10	DOWN	-6.25414672432555	7.55300940340142e-10	Toll-like receptor signaling pathway: TNF
hsa05164__34	4.04122715921686e-10	DOWN	-6.25300022630093	7.60106689906755e-10	Influenza A: IL1B
hsa04210__86	4.10100729242004e-10	DOWN	-6.25070723025168	7.70579270245726e-10	Apoptosis: BCL2L11
hsa04621__28	4.34887907217346e-10	DOWN	-6.24153524605469	8.16338039621772e-10	NOD-like receptor signaling pathway: CASP8
hsa05205__220	4.57771734834835e-10	DOWN	-6.23350975988232	8.58436217320015e-10	Proteoglycans in cancer: FAS
hsa04151__5	4.61135337910481e-10	UP	6.23236326185769	8.63881654968886e-10	PI3K-Akt signaling pathway: EIF4B
hsa04921__77	4.64523059092042e-10	DOWN	-6.23121676383307	8.68496346302435e-10	Oxytocin signaling pathway: KCNJ3
hsa04922__59	4.64523059092042e-10	DOWN	-6.23121676383307	8.68496346302435e-10	Glucagon signaling pathway: CPT1C
hsa05142__44	4.7831851106697e-10	DOWN	-6.22663077173457	8.93400081804012e-10	Chagas disease (American trypanosomiasis): PLCB1
hsa05030__78	4.92513536354646e-10	DOWN	-6.22204477963607	9.18999935263535e-10	Cocaine addiction: GRIA2
hsa04068__68	5.07119401066486e-10	DOWN	-6.21745878753758	9.45314835916594e-10	FoxO signaling pathway: ATG12
hsa04621__21 30	5.18350364017888e-10	DOWN	-6.2140192934637	9.65292699692381e-10	NOD-like receptor signaling pathway: NLRP3 PYCARD
hsa04910__24	5.29823927977407e-10	UP	6.21057979938983	9.85682337296583e-10	Insulin signaling pathway: ACACA
hsa05131__38	5.49499551731705e-10	DOWN	-6.20484730926671	1.02127562581986e-09	Shigellosis: CXCL8
hsa05205__81	6.73581147011098e-10	UP	6.17274536457723	1.25065116129827e-09	Proteoglycans in cancer: CTTN
hsa05168__91 92	7.0864255820636e-10	DOWN	-6.16471987840486	1.3144514974035e-09	Herpes simplex infection: STAT1 IRF9
hsa05212__27	7.95601488821218e-10	UP	6.14637591001087	1.47429506656318e-09	Pancreatic cancer: BCL2L1*
hsa04921__56	8.30824719690586e-10	DOWN	-6.13949692186312	1.53804891457991e-09	Oxytocin signaling pathway: JUN
hsa04014__41	8.55147054048503e-10	DOWN	-6.13491092976463	1.57996196121646e-09	Ras signaling pathway: RAC1*
hsa05216__15	8.55147054048503e-10	DOWN	-6.13491092976463	1.57996196121646e-09	Thyroid cancer: CCND1
hsa04728__32	8.67567261072433e-10	DOWN	-6.13261793371538	1.6013348561445e-09	Dopaminergic synapse: CREB3
hsa04010__129	8.73843165494118e-10	UP	6.13147143569075	1.61133592538121e-09	MAPK signaling pathway: FOS
hsa04666__29	8.80163339039341e-10	DOWN	-6.13032493766613	1.62139893534796e-09	Fc gamma R-mediated phagocytosis: WAS
hsa04066__54	9.256698738364e-10	DOWN	-6.12229945149376	1.70355895488599e-09	HIF-1 signaling pathway: SERPINE1
hsa04024__77	9.39087829618843e-10	DOWN	-6.12000645544451	1.72487393143089e-09	cAMP signaling pathway: RHOA*
hsa04151__36	9.39087829618843e-10	DOWN	-6.12000645544451	1.72487393143089e-09	PI3K-Akt signaling pathway: PCK1
hsa04931__124	9.87561011371838e-10	DOWN	-6.11198096927214	1.81213587926532e-09	Insulin resistance: FOXO1*
hsa05205__103	1.01634650069663e-09	DOWN	-6.10739497717364	1.86313665835022e-09	Proteoglycans in cancer: CCND1
hsa05200__194	1.03104443124975e-09	DOWN	-6.1051019811244	1.88823829075855e-09	Pathways in cancer: BCL2
hsa04620__29	1.09979037028325e-09	DOWN	-6.09478349890278	2.0121773181716e-09	Toll-like receptor signaling pathway: CXCL8
hsa04064__128	1.10769922209228e-09	DOWN	-6.09363700087815	2.02467591275427e-09	NF-kappa B signaling pathway: IL1B*
hsa04723__7	1.1156635160724e-09	DOWN	-6.09249050285353	2.03725145451898e-09	Retrograde endocannabinoid signaling: ITPR1
hsa04728__74	1.15632994051532e-09	DOWN	-6.08675801273041	2.1094601536197e-09	Dopaminergic synapse: GRIN2A
hsa04115__9	1.16463491610873e-09	UP	6.08561151470578	2.12254995865015e-09	p53 signaling pathway: RPRM
hsa04720__32	1.19844021238079e-09	DOWN	-6.08102552260729	2.18204375878246e-09	Long-term potentiation: ITPR1
hsa04923__38	1.25094869521513e-09	DOWN	-6.07414653445954	2.27544297997022e-09	Regulation of lipolysis in adipocytes: PDE3B
hsa05200__185	1.35309962582467e-09	DOWN	-6.06153505618867	2.45887253087482e-09	Pathways in cancer: HHIP
hsa04610__45	1.4738125264039e-09	DOWN	-6.04777707989318	2.67564612281442e-09	Complement and coagulation cascades: C4A
hsa03320__21	1.65120384082423e-09	DOWN	-6.02943311149919	2.9947992441204e-09	PPAR signaling pathway: ACAA1
hsa05150__48	1.69870517499228e-09	DOWN	-6.02484711940069	3.077981700878e-09	Staphylococcus aureus infection: C3AR1
hsa04068__46	1.7977359399437e-09	DOWN	-6.0156751352037	3.25428307432969e-09	FoxO signaling pathway: PLK4
hsa04668__153	1.88898518096472e-09	DOWN	-6.00764964903133	3.41617243025284e-09	TNF signaling pathway: MAPK14*
hsa04932__96	1.90238375725503e-09	DOWN	-6.00650315100671	3.4370952691175e-09	Non-alcoholic fatty liver disease (NAFLD): IL6*
hsa05164__35	1.92945926595217e-09	DOWN	-6.00421015495746	3.4826647077081e-09	Influenza A: IL18
hsa05221__41	2.01295792527818e-09	DOWN	-5.99733116680971	3.62989245834711e-09	Acute myeloid leukemia: MAPK1
hsa05213__11	2.19064846560654e-09	DOWN	-5.98357319051422	3.94652777265071e-09	Endometrial cancer: FOXO3
hsa04930__10	2.23740526246928e-09	UP	5.98013369644035	4.02690085074692e-09	Type II diabetes mellitus: C00031
hsa04670__39	2.25320580897455e-09	DOWN	-5.97898719841572	4.05145810053892e-09	Leukocyte transendothelial migration: MAPK14
hsa04622__21 22 23	2.26911502821138e-09	UP	5.9778407003911	4.07616361186347e-09	RIG-I-like receptor signaling pathway: CHUK IKBKB IKBKG
hsa04068__50	2.28513364655146e-09	DOWN	-5.97669420236647	4.10101826348634e-09	FoxO signaling pathway: TNFSF10
hsa05140__16	2.41730969235578e-09	UP	5.96752221816948	4.33408865642797e-09	Leishmaniasis: STAT1
hsa05231__60	2.72337777584811e-09	DOWN	-5.94803175175087	4.87819527246768e-09	Choline metabolism in cancer: PRKCA
hsa04024__31	2.80070256496144e-09	DOWN	-5.94344575965237	5.00715520415086e-09	cAMP signaling pathway: C00165
hsa04024__32	2.80070256496144e-09	DOWN	-5.94344575965237	5.00715520415086e-09	cAMP signaling pathway: C01245
hsa05110__46	2.90036952429137e-09	DOWN	-5.93771326952925	5.18041286705654e-09	Vibrio cholerae infection: PLCG1
hsa04925__34	3.08854310580192e-09	UP	5.92739478730763	5.51127492478805e-09	Aldosterone synthesis and secretion: STAR
hsa05205__22	3.1101708957683e-09	DOWN	-5.926248289283	5.54460257414482e-09	Proteoglycans in cancer: PPP1R12A
hsa04010__120	3.33472085908597e-09	DOWN	-5.91478330903676	5.93928008931047e-09	MAPK signaling pathway: NFATC1
hsa04151__25	3.38148800106402e-09	DOWN	-5.91249031298751	6.01687116855993e-09	PI3K-Akt signaling pathway: CDKN1B
hsa04115__20	3.55025532506297e-09	UP	5.90446482681514	6.30522661228103e-09	p53 signaling pathway: RRM2B
hsa04931__47	3.55025532506297e-09	UP	5.90446482681514	6.30522661228103e-09	Insulin resistance: AKT2*
hsa05321__94	3.57502462035468e-09	DOWN	-5.90331832879052	6.34322121024215e-09	Inflammatory bowel disease (IBD): IL22
hsa04340__33	3.59996210996089e-09	DOWN	-5.90217183076589	6.38144226850615e-09	Hedgehog signaling pathway: HHIP*
hsa04115__36	3.62506890299249e-09	UP	5.90102533274127	6.4138460157466e-09	p53 signaling pathway: EI24
hsa04610__57	3.62506890299249e-09	UP	5.90102533274127	6.4138460157466e-09	Complement and coagulation cascades: PLAUR
hsa05168__122	3.80565161398853e-09	UP	5.8929998465689	6.72701729321208e-09	Herpes simplex infection: CASP3
hsa05220__19 41	3.8588352387683e-09	DOWN	-5.89070685051965	6.81461599026846e-09	Chronic myeloid leukemia: SMAD4 SMAD3
hsa04722__50	3.93996960404054e-09	DOWN	-5.88726735644578	6.95136421219922e-09	Neurotrophin signaling pathway: RHOA
hsa04740__39	4.13579372264522e-09	DOWN	-5.87924187027341	7.29001538916544e-09	Olfactory transduction: PRKG1*
hsa05200__186	4.22258892693322e-09	UP	5.87580237619954	7.43603054705485e-09	Pathways in cancer: PTCH1*
hsa04911__24	4.34107801754925e-09	DOWN	-5.87121638410104	7.63753332862832e-09	Insulin secretion: INS
hsa05152__97	4.46280048177644e-09	DOWN	-5.86663039200254	7.8443424745163e-09	Tuberculosis: IL18
hsa05200__227	4.88177857598288e-09	DOWN	-5.85172591768243	8.57276817221666e-09	Pathways in cancer: FOXO1
hsa04922__24	4.94914955320859e-09	UP	5.84943292163318	8.6829617278048e-09	Glucagon signaling pathway: PFKL
hsa04930__7	5.01822476427417e-09	DOWN	-5.84713992558393	8.79593687693206e-09	Type II diabetes mellitus: C00002
hsa04611__25	5.15837887015555e-09	DOWN	-5.84255393348543	9.03317231782132e-09	Platelet activation: ORAI1
hsa05132__8	5.19400815776114e-09	DOWN	-5.84140743546081	9.07864309621691e-09	Salmonella infection: TJP1
hsa05168__123	5.19400815776114e-09	UP	5.84140743546081	9.07864309621691e-09	Herpes simplex infection: CYCS
hsa04152__63	5.22987683768936e-09	DOWN	-5.84026093743618	9.13284254462669e-09	AMPK signaling pathway: PPARG
hsa04151__32	5.48779295555108e-09	DOWN	-5.83223545126381	9.57433887045541e-09	PI3K-Akt signaling pathway: BCL2L1
hsa04152__15	5.56372845625329e-09	DOWN	-5.82994245521456	9.69781611252314e-09	AMPK signaling pathway: FOXO1
hsa04340__20 22	5.67955178606166e-09	UP	5.82650296114069	9.88136833889802e-09	Hedgehog signaling pathway: GLI1 SUFU*
hsa05162__78	5.67955178606166e-09	DOWN	-5.82650296114069	9.88136833889802e-09	Measles: FAS
hsa04961__13	5.91827738111125e-09	DOWN	-5.81962397299294	1.0277673936329e-08	Endocrine and other factor-regulated calcium reabsorption: ATP2B1
hsa05120__52	5.91827738111125e-09	DOWN	-5.81962397299294	1.0277673936329e-08	Epithelial cell signaling in Helicobacter pylori infection: LYN
hsa05200__53	6.12464693225147e-09	DOWN	-5.81389148286982	1.06262341511547e-08	Pathways in cancer: BCL2L1
hsa04726__39	6.92714947565004e-09	DOWN	-5.79325451842659	1.20074851150797e-08	Serotonergic synapse: CACNA1C
hsa04014__33	7.07048629399457e-09	DOWN	-5.78981502435271	1.22446486142081e-08	Ras signaling pathway: BCL2L1
hsa04912__17	7.11890308674854e-09	DOWN	-5.78866852632809	1.23171444751386e-08	GnRH signaling pathway: MAPK14
hsa04072__36	7.56941318005634e-09	UP	5.77835004410647	1.30845697933081e-08	Phospholipase D signaling pathway: MTOR
hsa04650__39	7.83155164599645e-09	DOWN	-5.77261755398335	1.35252624474516e-08	Natural killer cell mediated cytotoxicity: FAS
hsa04922__37	8.21342510152702e-09	UP	5.76459206781098	1.41717408317441e-08	Glucagon signaling pathway: PYGB
hsa04213__61	8.67203852812562e-09	DOWN	-5.75542008361398	1.49493214627046e-08	Longevity regulating pathway - multiple species: ATG5
hsa05231__18	8.73108684828511e-09	DOWN	-5.75427358558936	1.50373163959008e-08	Choline metabolism in cancer: CHKA
hsa04390__79	9.40697107484919e-09	UP	5.74166210731849	1.61865372249465e-08	Hippo signaling pathway: SNAI2
hsa04710__11	9.73075255123102e-09	DOWN	-5.73592961719537	1.67283477070111e-08	Circadian rhythm: CRY1
hsa04210__114	9.93019388629662e-09	DOWN	-5.7324901231215	1.70556072324967e-08	Apoptosis: HRK
hsa04064__130	1.12887646047976e-08	DOWN	-5.71070666065364	1.93359969848811e-08	NF-kappa B signaling pathway: TNF*
hsa04726__16	1.12887646047976e-08	DOWN	-5.71070666065364	1.93359969848811e-08	Serotonergic synapse: ITPR1
hsa04726__46	1.12887646047976e-08	DOWN	-5.71070666065364	1.93359969848811e-08	Serotonergic synapse: ITPR1*
hsa04064__3	1.21561347078788e-08	DOWN	-5.69809518238277	2.0802711399002e-08	NF-kappa B signaling pathway: BCL2
hsa04380__16	1.29136577534945e-08	DOWN	-5.68777670016115	2.20588753807419e-08	Osteoclast differentiation: NFKB1
hsa04390__14	1.29136577534945e-08	DOWN	-5.68777670016115	2.20588753807419e-08	Hippo signaling pathway: AREG
hsa04380__69	1.3088121818991e-08	DOWN	-5.6854837041119	2.23365857383143e-08	Osteoclast differentiation: NFKB2
hsa04015__17	1.37169645848319e-08	DOWN	-5.67745821793953	2.33885448774039e-08	Rap1 signaling pathway: ACTB
hsa04921__59	1.38091618920031e-08	DOWN	-5.67631171991491	2.35244018087705e-08	Oxytocin signaling pathway: CCND1
hsa05215__25	1.39019611037809e-08	DOWN	-5.67516522189028	2.36610370597866e-08	Prostate cancer: FOXO1
hsa05220__25	1.40893804912912e-08	DOWN	-5.67287222584103	2.39583221204851e-08	Chronic myeloid leukemia: BCL2L1*
hsa04360__21	1.46664850873478e-08	UP	5.66599323769329	2.49171116447798e-08	Axon guidance: PAK4
hsa04064__137	1.51648883837061e-08	DOWN	-5.66026074757017	2.57173513294078e-08	NF-kappa B signaling pathway: ICAM1
hsa04810__32	1.51648883837061e-08	DOWN	-5.66026074757017	2.57173513294078e-08	Regulation of actin cytoskeleton: PXN
hsa05215__22	1.52694856613268e-08	UP	4.43924035134529	2.58713828292452e-08	Prostate cancer: C16038
hsa04015__3	1.5679727056652e-08	UP	5.65452825744705	2.65425289544587e-08	Rap1 signaling pathway: MAPK1
hsa04360__40 142	1.65389696942987e-08	DOWN	-5.64535627325005	2.7971848834912e-08	Axon guidance: UNC5D PTPN11
hsa03320__58	1.67608246695663e-08	DOWN	-5.6430632772008	2.83215733400315e-08	PPAR signaling pathway: CYP8B1
hsa05010__12	1.69855686985245e-08	UP	5.64077028115155	2.86755467965207e-08	Alzheimer's disease: CASP3
hsa04010__88 92	1.94001439648309e-08	DOWN	-5.61784032065907	3.26931574079975e-08	MAPK signaling pathway: ECSIT TRAF6
hsa04340__32	1.94001439648309e-08	UP	5.61784032065907	3.26931574079975e-08	Hedgehog signaling pathway: PTCH1***
hsa04920__9	2.03215184208158e-08	DOWN	-5.6098148344867	3.42151730400654e-08	Adipocytokine signaling pathway: G6PC
hsa04360__35	2.05924794972846e-08	DOWN	-5.60752183843745	3.46403482322272e-08	Axon guidance: ROCK1*
hsa03320__36	2.08669467309891e-08	DOWN	-5.6052288423882	3.5070655552351e-08	PPAR signaling pathway: SLC27A4
hsa04915__21	2.51032150059077e-08	DOWN	-5.57312689769872	4.21527622842722e-08	Estrogen signaling pathway: CREB3
hsa04115__1	2.54358519133846e-08	UP	5.57083390164947	4.26731837011157e-08	p53 signaling pathway: SIAH1
hsa04350__32	2.75233502632925e-08	UP	5.55707592535398	4.61341437508712e-08	TGF-beta signaling pathway: RPS6KB1
hsa04390__17 51	2.78870574723636e-08	DOWN	-5.55478292930473	4.67021220949832e-08	Hippo signaling pathway: YWHAQ YAP1
hsa04360__117	3.0367401066149e-08	DOWN	-5.53987845498462	5.076543292108e-08	Axon guidance: CFL1*
hsa05321__19	3.0367401066149e-08	DOWN	-5.53987845498462	5.076543292108e-08	Inflammatory bowel disease (IBD): TNF
hsa04270__65	3.07673456087753e-08	DOWN	-5.53758545893537	5.13429424131256e-08	Vascular smooth muscle contraction: NPR2
hsa04024__123	3.07675109937091e-08	UP	5.53758545893537	5.13429424131256e-08	cAMP signaling pathway: PAK1
hsa04662__10	3.11727332387611e-08	UP	5.53529246288612	5.18809262671675e-08	B cell receptor signaling pathway: GSK3B
hsa05214__27	3.11727332387611e-08	UP	5.53529246288612	5.18809262671675e-08	Glioma: MTOR
hsa05214__48	3.11727332387611e-08	UP	5.53529246288612	5.18809262671675e-08	Glioma: MTOR*
hsa04520__10	3.19987680881631e-08	UP	5.53070647078762	5.32085710067774e-08	Adherens junction: NLK
hsa04912__43	3.28460199991496e-08	DOWN	-5.52612047868912	5.4569117222283e-08	GnRH signaling pathway: PTK2B
hsa04931__135	3.57525707076017e-08	UP	5.51121600436901	5.93454773494555e-08	Insulin resistance: SREBF1**
hsa04610__58	3.62213188860554e-08	UP	5.50892300831976	6.00704838366267e-08	Complement and coagulation cascades: F2RL2
hsa04922__78	3.79093403049558e-08	DOWN	-5.50089752214739	6.28145065546842e-08	Glucagon signaling pathway: ACACA
hsa05168__39 40	3.81566292628372e-08	UP	5.49975102412277	6.31685518809437e-08	Herpes simplex infection: POU2F3 HCFC2
hsa04360__123	3.86559088364071e-08	UP	5.49745802807352	6.39387787883882e-08	Axon guidance: ENAH
hsa04010__119	3.91615213214742e-08	DOWN	-5.49516503202427	6.46612465404657e-08	MAPK signaling pathway: NFATC3
hsa04610__23	3.91615213214742e-08	UP	5.49516503202427	6.46612465404657e-08	Complement and coagulation cascades: BDKRB1
hsa04520__9 57	4.15172504996949e-08	DOWN	-5.48484654980265	6.8490705609242e-08	Adherens junction: LEF1 CTNNB1
hsa05150__66	4.4295915494618e-08	DOWN	-5.47338156955641	7.3010548433673e-08	Staphylococcus aureus infection: IL10
hsa04924__52	4.69502416986138e-08	UP	5.46306308733479	7.73177074072702e-08	Renin secretion: KCNJ2
hsa04012__31	5.10582126013036e-08	UP	5.44815861301467	8.40090906110765e-08	ErbB signaling pathway: BAD
hsa04014__103	5.58715451105465e-08	DOWN	-5.43210764066993	9.18483230644942e-08	Ras signaling pathway: KSR2
hsa04211__51	5.69587543657025e-08	UP	5.42866814659606	9.35537582632474e-08	Longevity regulating pathway - mammal: NFKB1
hsa04918__10	6.39255506483501e-08	UP	5.40803118215282	1.04904899273581e-07	Thyroid hormone synthesis: TG
hsa04261__14 16	6.72805750884897e-08	DOWN	-5.39885919795583	1.10314311161669e-07	Adrenergic signaling in cardiomyocytes: TNNI3 TPM1
hsa05160__56	7.21734855994253e-08	UP	5.38624771968496	1.18233635083976e-07	Hepatitis C: MAPK1
hsa05205__195	7.30993882996034e-08	DOWN	-5.38395472363571	1.19646124229055e-07	Proteoglycans in cancer: CDKN1A
hsa04014__100	7.3566643660678e-08	DOWN	-5.38280822561109	1.20306112653102e-07	Ras signaling pathway: REL
hsa05217__5	7.49858322660801e-08	DOWN	-5.37936873153721	1.22520329415621e-07	Basal cell carcinoma: BMP2
hsa04670__2	8.62344478719238e-08	DOWN	-5.35414577499548	1.4077717424096e-07	Leukocyte transendothelial migration: MMP2
hsa05150__35	8.84473808947979e-08	DOWN	-5.34955978289698	1.44264434636567e-07	Staphylococcus aureus infection: FCAR
hsa05200__191	9.6029091885943e-08	DOWN	-5.33465530857687	1.56494938121151e-07	Pathways in cancer: CCND1*
hsa04210__58	9.91092339915527e-08	UP	5.32892281845375	1.61374567305137e-07	Apoptosis: BID*
hsa05161__31	1.02931758435839e-07	DOWN	-5.322043830306	1.6745348407008e-07	Hepatitis B: ELK1
hsa04024__116	1.0489615004092e-07	UP	5.31860433623213	1.70501614123606e-07	cAMP signaling pathway: ACOX1
hsa04211__39	1.10313565842109e-07	UP	5.30943235203513	1.79152281951013e-07	Longevity regulating pathway - mammal: TP53*
hsa03320__65	1.11709659218025e-07	UP	5.30713935598588	1.81262909905586e-07	PPAR signaling pathway: ME1
hsa04115__21	1.13122843932341e-07	UP	5.30484635993663	1.83397604615072e-07	p53 signaling pathway: DDB2
hsa04064__142	1.13835908488472e-07	DOWN	-5.30369986191201	1.84394544870551e-07	NF-kappa B signaling pathway: NFKB2*
hsa04340__49	1.14553321700444e-07	DOWN	-5.30255336388739	1.85237256002698e-07	Hedgehog signaling pathway: CCND1
hsa04520__44 49	1.14553321700444e-07	DOWN	-5.30255336388739	1.85237256002698e-07	Adherens junction: ACTB VCL
hsa05161__30	1.21209997460908e-07	DOWN	-5.29223488166577	1.9583283338697e-07	Hepatitis B: MYC
hsa04621__43	1.21972327757167e-07	DOWN	-5.29108838364114	1.96895192315908e-07	NOD-like receptor signaling pathway: MAPK1
hsa04210__57	1.28240243171432e-07	UP	5.28191639944415	2.06835551003538e-07	Apoptosis: BAK1
hsa04012__23	1.32314738030795e-07	DOWN	-5.27618390932103	2.13224179039335e-07	ErbB signaling pathway: RPS6KB1
hsa04931__137	1.33144532637696e-07	UP	5.2750374112964	2.1419398700876e-07	Insulin resistance: MLXIP*
hsa05140__43	1.33144532637696e-07	DOWN	-5.2750374112964	2.1419398700876e-07	Leishmaniasis: MAPK14
hsa04151__27	1.39966573824365e-07	DOWN	-5.26586542709941	2.24976212331892e-07	PI3K-Akt signaling pathway: FASLG
hsa04213__2	1.4530374920813e-07	UP	5.25898643895166	2.33156058720817e-07	Longevity regulating pathway - multiple species: RPS6KB1
hsa04340__14	1.4530374920813e-07	DOWN	-5.25898643895166	2.33156058720817e-07	Hedgehog signaling pathway: PTCH1
hsa04150__31	1.4621220626792e-07	DOWN	-5.25783994092704	2.34413596909063e-07	mTOR signaling pathway: EIF4E
hsa05032__30	1.55602680807947e-07	DOWN	-5.24637496068079	2.49256127227735e-07	Morphine addiction: ADORA1
hsa04740__37	1.57551363172914e-07	UP	5.24408196463155	2.52162701364485e-07	Olfactory transduction: CNGB1*
hsa04913__45	1.60516374490458e-07	DOWN	-5.24064247055767	2.56689589504316e-07	Ovarian steroidogenesis: ACOT2
hsa04912__46	1.61516648259272e-07	DOWN	-5.23949597253305	2.5806954258433e-07	GnRH signaling pathway: JUN
hsa04115__29	1.6353530918425e-07	DOWN	-5.2372029764838	2.61072936242316e-07	p53 signaling pathway: IGF1
hsa05219__10	1.82835314015092e-07	UP	5.21656601204056	2.91636294596228e-07	Bladder cancer: EGFR
hsa05162__20	1.93293436048326e-07	DOWN	-5.20624752981894	3.0805629036031e-07	Measles: NFKB1
hsa04510__20 4 5	2.06862364145833e-07	DOWN	-5.19363605154808	3.29402018839001e-07	Focal adhesion: VASP ITGB1 ITGA11
hsa05210__53	2.21349684533473e-07	DOWN	-5.18102457327721	3.52172783436407e-07	Colorectal cancer: CCND1*
hsa05321__75	2.25467924776686e-07	DOWN	-5.17758507920334	3.58421514936881e-07	Inflammatory bowel disease (IBD): IL10
hsa04210__63	2.50240305774592e-07	DOWN	-5.15809461278472	3.97465371555756e-07	Apoptosis: FAS*
hsa04666__42	2.77632242184382e-07	DOWN	-5.13860414636611	4.40600492453087e-07	Fc gamma R-mediated phagocytosis: MYO10
hsa04360__59	2.79330660052987e-07	UP	5.13745764834149	4.4292178079288e-07	Axon guidance: MAPK1*
hsa05020__49	2.8448633529466e-07	UP	5.13401815426761	4.50716546390106e-07	Prion diseases: BAX
hsa05212__10	2.96876118864699e-07	DOWN	-5.12599266809524	4.69949643931566e-07	Pancreatic cancer: BCL2L1
hsa04620__20	3.06043285600472e-07	UP	5.12026017797212	4.84053311147549e-07	Toll-like receptor signaling pathway: IFNB1*
hsa04722__46	3.23237462172104e-07	DOWN	-5.1099416957505	5.10818495728666e-07	Neurotrophin signaling pathway: ATF4*
hsa04340__13	3.25204519127027e-07	UP	5.10879519772588	5.13495202890491e-07	Hedgehog signaling pathway: GLI1*
hsa04151__34	3.27183130080656e-07	UP	5.10764869970126	5.16185643510959e-07	PI3K-Akt signaling pathway: GYS1
hsa04660__14	3.39301108510323e-07	DOWN	-5.10076971155351	5.34854683633303e-07	T cell receptor signaling pathway: NFKB1
hsa05161__130	3.53986661444212e-07	DOWN	-5.09274422538114	5.57536409768378e-07	Hepatitis B: FASLG*
hsa04014__54	4.01817877184102e-07	DOWN	-5.06866776686403	6.32341533692569e-07	Ras signaling pathway: RHOA
hsa04921__65	4.66915321087245e-07	DOWN	-5.04000531624842	7.34170617843458e-07	Oxytocin signaling pathway: TRPM2
hsa04950__13	6.03378426793812e-07	UP	4.99070590118958	9.47949886242117e-07	Maturity onset diabetes of the young: INS
hsa05200__207	6.63379907999873e-07	DOWN	-4.97236193279559	1.04134573695218e-06	Pathways in cancer: CDK4
hsa04012__57	6.67315027126277e-07	UP	4.97121543477096	1.0466485275211e-06	ErbB signaling pathway: ABL1
hsa05014__53	6.79255815941362e-07	DOWN	-4.96777594069709	1.06448847218834e-06	Amyotrophic lateral sclerosis (ALS): RAB5A
hsa04024__12	7.16326373996975e-07	UP	4.95745745847547	1.12164771395026e-06	cAMP signaling pathway: SLC9A1
hsa04024__107 64	7.2482509358316e-07	UP	4.95516446242622	1.13401028379913e-06	cAMP signaling pathway: NFKBIA NFKB1
hsa05205__144	7.33420916417561e-07	DOWN	-4.95287146637697	1.14650407816023e-06	Proteoglycans in cancer: NUDT16L1
hsa04530__8	7.37755573543384e-07	DOWN	-4.95172496835235	1.15136438761463e-06	Tight junction: LLGL2
hsa04917__34	7.37755573543384e-07	DOWN	-4.95172496835235	1.15136438761463e-06	Prolactin signaling pathway: ELF5
hsa04012__65	7.77894201888276e-07	UP	4.94140648613073	1.2129985106623e-06	ErbB signaling pathway: MYC
hsa04912__20	7.87095375777148e-07	DOWN	-4.93911349008148	1.22632853323819e-06	GnRH signaling pathway: PLA2G4B
hsa04151__102	8.01093968710726e-07	DOWN	-4.93567399600761	1.24710486098381e-06	PI3K-Akt signaling pathway: C8orf44-SGK3
hsa04550__34	8.10559257872714e-07	DOWN	-4.93338099995836	1.26079540193943e-06	Signaling pathways regulating pluripotency of stem cells: MAPK1*
hsa04115__39	8.34696102627575e-07	UP	4.92764850983524	1.29726548952623e-06	p53 signaling pathway: BAX
hsa04810__23	8.39605845361008e-07	DOWN	-4.92650201181062	1.30274102678227e-06	Regulation of actin cytoskeleton: GSN
hsa05150__1 2 3	8.39605845361008e-07	DOWN	-4.92650201181062	1.30274102678227e-06	Staphylococcus aureus infection: CFD C3 CFB
hsa05169__29	8.69653550142224e-07	DOWN	-4.91962302366287	1.34825001709343e-06	Epstein-Barr virus infection: FCER2
hsa05223__37	9.22047952730029e-07	DOWN	-4.90815804341663	1.42830016750183e-06	Non-small cell lung cancer: CCND1*
hsa04742__46	1.01816602902731e-06	UP	4.88866757699801	1.57589289006781e-06	Taste transduction: P2RY1
hsa05321__55	1.02411217002723e-06	DOWN	-4.88752107897339	1.58379157817379e-06	Inflammatory bowel disease (IBD): IL4*
hsa04722__85	1.04822681366193e-06	DOWN	-4.88293508687489	1.61975179512399e-06	Neurotrophin signaling pathway: BAX
hsa04360__82	1.1238944862002e-06	DOWN	-4.8691771105794	1.73524875889085e-06	Axon guidance: ILK
hsa04390__89	1.15695035055036e-06	DOWN	-4.86344462045628	1.78481913685068e-06	Hippo signaling pathway: ID2
hsa04064__132	1.21179384976989e-06	DOWN	-4.85427263625929	1.86789224259034e-06	NF-kappa B signaling pathway: VCAM1
hsa04911__56	1.23299809675493e-06	DOWN	-4.85083314218541	1.89901919983812e-06	Insulin secretion: CAMK2A*
hsa04024__108	1.2764824479338e-06	UP	4.84395415403767	1.96438207998986e-06	cAMP signaling pathway: AMH
hsa05160__71	1.29130228132599e-06	UP	4.84166115798842	1.98556218216983e-06	Hepatitis C: MAPK8
hsa05321__46	1.30628754008214e-06	DOWN	-4.83936816193917	2.00696180524475e-06	Inflammatory bowel disease (IBD): IFNG*
hsa05160__77	1.31384275542271e-06	DOWN	-4.83822166391454	2.0169203737249e-06	Hepatitis C: NFKB1*
hsa04115__22	1.33676141915157e-06	UP	4.83478216984067	2.05042833190678e-06	p53 signaling pathway: STEAP3
hsa05211__2	1.39174330731519e-06	DOWN	-4.8267566836683	2.13302257295697e-06	Renal cell carcinoma: TGFB1
hsa04360__101 103	1.40784770926308e-06	UP	4.82446368761905	2.15594608451942e-06	Axon guidance: DPYSL2 DPYSL5
hsa04540__11	1.67201149395636e-06	UP	4.79006874688032	2.55839543741368e-06	Gap junction: C00780
hsa04064__97	1.7401796564772e-06	DOWN	-4.78204326070795	2.66053504843015e-06	NF-kappa B signaling pathway: PLCG2
hsa04064__134	1.77020518787829e-06	DOWN	-4.77860376663408	2.70424028294578e-06	NF-kappa B signaling pathway: CCL21
hsa05152__78	1.83175667599207e-06	DOWN	-4.77172477848633	2.79599577107157e-06	Tuberculosis: IL1A
hsa05161__188	2.01752357833616e-06	UP	4.75223431206772	3.07705097702406e-06	Hepatitis B: IFNB1
hsa05205__183	2.18397112048945e-06	UP	4.73618333972298	3.32820903114329e-06	Proteoglycans in cancer: VEGFA*
hsa04110__48	2.19635190374087e-06	UP	4.73503684169836	3.34165605435554e-06	Cell cycle: RB1*
hsa05152__51	2.19635190374087e-06	UP	4.73503684169836	3.34165605435554e-06	Tuberculosis: CASP3
hsa05166__99	2.35027886834517e-06	DOWN	-4.72127886540287	3.57295630551827e-06	HTLV-I infection: JUN
hsa04550__47	2.40385134666608e-06	DOWN	-4.71669287330437	3.65144436571186e-06	Signaling pathways regulating pluripotency of stem cells: CTNNB1*
hsa05169__93	2.43107530336684e-06	DOWN	-4.71439987725512	3.68981461633787e-06	Epstein-Barr virus infection: PLCG1
hsa04621__44	2.50043627702791e-06	DOWN	-4.708667387132	3.79202563723602e-06	NOD-like receptor signaling pathway: MAPK14
hsa05162__93	2.58617844821446e-06	UP	4.70178839898425	3.91889460015724e-06	Measles: TP53
hsa04919__18	2.70490036642553e-06	DOWN	-4.69261641478726	4.09549378607057e-06	Thyroid hormone signaling pathway: STAT1
hsa05012__70	2.92535735141648e-06	DOWN	-4.67656544244252	4.42572179010593e-06	Parkinson's disease: PRKACA
hsa04015__30	2.99144698056396e-06	DOWN	-4.67197945034402	4.51843157273287e-06	Rap1 signaling pathway: ITGAL
hsa04310__16	2.99144698056396e-06	UP	4.67197945034402	4.51843157273287e-06	Wnt signaling pathway: CAMK2A
hsa04931__13	3.09327396842011e-06	DOWN	-4.66510046219628	4.66848336278023e-06	Insulin resistance: AKT2
hsa05152__76	3.400159281275e-06	DOWN	-4.64560999577766	5.12752751967555e-06	Tuberculosis: TNF*
hsa05212__8	3.43812655878196e-06	DOWN	-4.64331699972841	5.18062534398661e-06	Pancreatic cancer: NFKB1
hsa04912__19	3.49584067644481e-06	DOWN	-4.63987750565454	5.25915502885492e-06	GnRH signaling pathway: MAPK7
hsa04919__43	3.49584067644481e-06	DOWN	-4.63987750565454	5.25915502885492e-06	Thyroid hormone signaling pathway: TBC1D4
hsa05142__18	3.65432218785069e-06	DOWN	-4.63070552145755	5.49317711277715e-06	Chagas disease (American trypanosomiasis): FOS
hsa05100__24	4.48130596589892e-06	DOWN	-4.58828509454645	6.73091439642211e-06	Bacterial invasion of epithelial cells: ACTB
hsa04725__53	4.58073298113987e-06	UP	4.58369910244795	6.87475820412285e-06	Cholinergic synapse: CHRNA7
hsa04621__6	4.60595375099804e-06	DOWN	-4.58255260442333	6.90158460775543e-06	NOD-like receptor signaling pathway: NFKB1
hsa05168__9	4.60595375099804e-06	DOWN	-4.58255260442333	6.90158460775543e-06	Herpes simplex infection: NFKB1
hsa04062__40	4.70805649439898e-06	DOWN	-4.57796661232483	7.04895470356628e-06	Chemokine signaling pathway: PRKACA
hsa05100__33	4.73391892135725e-06	UP	4.5768201143002	7.0820331633999e-06	Bacterial invasion of epithelial cells: DNM1
hsa04726__38	4.83873593731046e-06	DOWN	-4.57223412220171	7.23308259841397e-06	Serotonergic synapse: PLA2G4B
hsa04919__88	4.89197444784894e-06	DOWN	-4.56994112615246	7.30685213633399e-06	Thyroid hormone signaling pathway: FOXO1
hsa05110__12	5.30953013252118e-06	DOWN	-4.55274365578309	7.9179421579423e-06	Vibrio cholerae infection: C00080
hsa05120__35	5.30953013252118e-06	DOWN	-4.55274365578309	7.9179421579423e-06	Epithelial cell signaling in Helicobacter pylori infection: C00080
hsa05231__17	5.85570647176414e-06	UP	4.53210669133986	8.72551344999589e-06	Choline metabolism in cancer: SLC44A3
hsa05231__59	6.21552966142257e-06	DOWN	-4.51949521306899	9.25434249905943e-06	Choline metabolism in cancer: PLA2G4B
hsa04650__15	6.74043190477862e-06	DOWN	-4.50229774269962	1.00279268005376e-05	Natural killer cell mediated cytotoxicity: TNF
hsa04010__117	6.81354310384794e-06	UP	4.50000474665038	1.01286768133942e-05	MAPK signaling pathway: JUND
hsa05166__34 35 36	7.34692633593016e-06	DOWN	-4.48395377430564	1.09129443361366e-05	HTLV-I infection: MYC TRRAP KAT5
hsa05200__200	7.83577532056666e-06	DOWN	-4.47019579801014	1.16298750610938e-05	Pathways in cancer: FIGF
hsa05133__30	7.92020707198103e-06	DOWN	-4.4679028019609	1.17459108825985e-05	Pertussis: NOS2
hsa05210__40	8.13510836610618e-06	UP	4.46217031183777	1.2055101435263e-05	Colorectal cancer: CASP9
hsa04024__25	8.7202488536805e-06	DOWN	-4.44726583751766	1.29120154421321e-05	cAMP signaling pathway: CFTR
hsa04350__41	9.24658124047655e-06	UP	4.43465435924679	1.36805717723271e-05	TGF-beta signaling pathway: SMAD4***
hsa04931__144	9.34548308947948e-06	DOWN	-4.43236136319754	1.38160210268544e-05	Insulin resistance: C00533*
hsa05160__54	9.5463270886324e-06	DOWN	-4.42777537109905	1.41018463832864e-05	Hepatitis C: IRF1
hsa05222__36	1.04468494419626e-05	DOWN	-4.40828490468043	1.54199765133132e-05	Small cell lung cancer: PTGS2
hsa04151__98	1.06702318225639e-05	DOWN	-4.40369891258193	1.57373356315522e-05	PI3K-Akt signaling pathway: BCL2L1*
hsa05145__8	1.07267859637836e-05	DOWN	-4.40255241455731	1.58083379027055e-05	Toxoplasmosis: NFKB1
hsa04713__56	1.16102152267238e-05	DOWN	-4.38535494418795	1.70968608236787e-05	Circadian entrainment: KCNJ3
hsa04012__35	1.19198218806558e-05	UP	4.37962245406482	1.75390331352798e-05	ErbB signaling pathway: CBLC
hsa05223__23	1.28966257617022e-05	DOWN	-4.36242498369546	1.89614708969001e-05	Non-small cell lung cancer: CASP9*
hsa04062__59	1.31697331953066e-05	DOWN	-4.35783899159696	1.93478723017835e-05	Chemokine signaling pathway: FOXO3
hsa04970__39	1.33082499504399e-05	UP	4.35554599554771	1.9520987411271e-05	Salivary secretion: KCNN4
hsa04024__113	1.33083474581363e-05	DOWN	-4.35554599554771	1.9520987411271e-05	cAMP signaling pathway: PTCH1
hsa04062__42	1.34483528477079e-05	UP	4.35325299949847	1.97109633391912e-05	Chemokine signaling pathway: PAK1
hsa05162__101	1.41697134602594e-05	UP	4.34178801925222	2.0752058918026e-05	Measles: CDKN1B
hsa04210__52	1.62219865667518e-05	UP	4.31197907061199	2.37391843916875e-05	Apoptosis: PARP2
hsa04630__34	1.63063212776133e-05	DOWN	-4.31083257258737	2.38440293234517e-05	Jak-STAT signaling pathway: AOX1
hsa04064__53	1.66478576270448e-05	DOWN	-4.30624658048887	2.43245135934815e-05	NF-kappa B signaling pathway: CXCL8
hsa04014__70	1.68211719248378e-05	UP	4.30395358443962	2.45395823344489e-05	Ras signaling pathway: RIN1*
hsa05220__15	1.68211719248378e-05	UP	4.30395358443962	2.45395823344489e-05	Chronic myeloid leukemia: MYC
hsa04550__22	1.78055571135172e-05	UP	4.29134210616875	2.59555017969735e-05	Signaling pathways regulating pluripotency of stem cells: SMAD2
hsa05169__83	1.90397106075331e-05	UP	4.27643763184864	2.77330358384144e-05	Epstein-Barr virus infection: GSK3B
hsa04310__57	1.93358694446791e-05	UP	4.27299813777477	2.81426016162293e-05	Wnt signaling pathway: SIAH1
hsa04210__73	2.01472269382438e-05	DOWN	-4.26382615357777	2.93008045022911e-05	Apoptosis: TRAF1
hsa04750__7	2.04595971195695e-05	UP	4.2603866595039	2.97091058637334e-05	Inflammatory mediator regulation of TRP channels: TRPV1
hsa04750__58	2.04595971195695e-05	UP	4.2603866595039	2.97091058637334e-05	Inflammatory mediator regulation of TRP channels: TRPV1**
hsa04932__95	2.1980304235016e-05	DOWN	-4.24433568715916	3.18926576506526e-05	Non-alcoholic fatty liver disease (NAFLD): IL1A
hsa05010__37	2.23198432552768e-05	DOWN	-4.24089619308528	3.23603282998959e-05	Alzheimer's disease: MAPT
hsa04620__66	2.26643705875077e-05	DOWN	-4.23745669901141	3.28345044980162e-05	Toll-like receptor signaling pathway: CASP8
hsa04360__29	2.36080261617788e-05	UP	4.22828471481442	3.41752551294163e-05	Axon guidance: RASA1
hsa05145__35	2.92075517779255e-05	UP	4.1801317977802	4.22486449505174e-05	Toxoplasmosis: CASP3
hsa04668__116	2.95034508605567e-05	DOWN	-4.17783880173095	4.26438339746046e-05	TNF signaling pathway: PGAM5
hsa04012__56	3.07157852333224e-05	UP	4.16866681753395	4.43619988112319e-05	ErbB signaling pathway: JUN
hsa04066__59	3.21362184968056e-05	DOWN	-4.15834833531233	4.63422521531064e-05	HIF-1 signaling pathway: NOS2
hsa04115__49	3.21362184968056e-05	UP	4.15834833531233	4.63422521531064e-05	p53 signaling pathway: MDM2*
hsa05321__92	3.29520907143622e-05	DOWN	-4.15261584518921	4.74823454388701e-05	Inflammatory bowel disease (IBD): IL17F
hsa04068__42	3.73352768748138e-05	DOWN	-4.12395339457361	5.37159151973776e-05	FoxO signaling pathway: CDKN2D
hsa04722__35	3.73352768748138e-05	DOWN	-4.12395339457361	5.37159151973776e-05	Neurotrophin signaling pathway: FOXO3
hsa04912__15	3.77088735726071e-05	DOWN	-4.12166039852436	5.42119154115751e-05	GnRH signaling pathway: CAMK2A
hsa04360__33 134	3.80860173547917e-05	DOWN	-4.11936740247511	5.4712252759674e-05	Axon guidance: NCK1 PAK4
hsa04540__12	4.02251410797767e-05	UP	4.10675592420424	5.77410543077925e-05	Gap junction: C00025
hsa04917__37	4.08280363142742e-05	UP	4.10331643013037	5.85617406370391e-05	Prolactin signaling pathway: TNFSF11
hsa05016__12	4.1234719422096e-05	DOWN	-4.10102343408112	5.9099952550815e-05	Huntington's disease: REST
hsa04725__50	4.29002123336785e-05	UP	4.09185144988413	6.14401669016631e-05	Cholinergic synapse: BCL2
hsa04650__119	4.75810487332067e-05	UP	4.06777499136702	6.80919958642006e-05	Natural killer cell mediated cytotoxicity: KLRC4-KLRK1
hsa04110__46	4.80512586677066e-05	UP	4.06548199531777	6.87125685210203e-05	Cell cycle: RB1
hsa04152__57	4.92461324058174e-05	UP	4.05974950519465	7.03676675213163e-05	AMPK signaling pathway: ACACA*
hsa04115__31	4.94884630200172e-05	DOWN	-4.05860300717002	7.06601990992494e-05	p53 signaling pathway: ADGRB1
hsa04064__52	5.32618392848137e-05	DOWN	-4.04140553680066	7.59901260563136e-05	NF-kappa B signaling pathway: TRAF1
hsa03320__45	5.43131986899416e-05	DOWN	-4.03681954470216	7.74313356133537e-05	PPAR signaling pathway: PDPK1
hsa05020__24	5.48875736564168e-05	UP	4.03338005062829	7.80134273074185e-05	Prion diseases: PRNP*
hsa05020__26	5.48875736564168e-05	UP	4.03338005062829	7.80134273074185e-05	Prion diseases: PRNP**
hsa05020__25 8	5.48875736564168e-05	UP	4.03338005062829	7.80134273074185e-05	Prion diseases: PRNP PRNP*
hsa05020__10 34	5.48875736564168e-05	UP	4.03338005062829	7.80134273074185e-05	Prion diseases: PRNP PRNP***
hsa04932__97	5.59271739493419e-05	DOWN	-4.02994055655441	7.94309598267675e-05	Non-alcoholic fatty liver disease (NAFLD): TNF*
hsa05215__24	5.84335620873318e-05	DOWN	-4.01962207433279	8.29279933248463e-05	Prostate cancer: CDKN1A
hsa04115__34	6.16414663342285e-05	UP	4.00701059606193	8.74145775411437e-05	p53 signaling pathway: ZMAT3
hsa04720__4 15	6.22423518272778e-05	DOWN	-4.00471760001268	8.82001350553959e-05	Long-term potentiation: CREBBP ATF4
hsa05145__11	6.25448699980806e-05	UP	4.00357110198805	8.85620276762573e-05	Toxoplasmosis: MAPK14
hsa04024__62	6.28487797452648e-05	DOWN	-4.00242460396343	8.89253442329463e-05	cAMP signaling pathway: BAD
hsa04024__93	6.43894129621842e-05	UP	3.99669211384031	9.0968200718755e-05	cAMP signaling pathway: ORAI1
hsa04210__119	6.43894129621842e-05	DOWN	-3.99669211384031	9.0968200718755e-05	Apoptosis: BCL2*
hsa04012__47	6.79055599143812e-05	DOWN	-3.98408063556944	9.58636717348777e-05	ErbB signaling pathway: PRKCA
hsa04970__45	7.02366862795957e-05	DOWN	-3.97605514939707	9.908013026979e-05	Salivary secretion: KCNMA1
hsa04360__19	7.36990253995376e-05	UP	3.96459016915083	0.00010388632312508	Axon guidance: CDC42
hsa04933__43	7.4410550515105e-05	DOWN	-3.96229717310158	0.000104810662981921	AGE-RAGE signaling pathway in diabetic complications: CASP3
hsa05215__30	8.58944550380371e-05	UP	3.92790223236285	0.00012089564121084	Prostate cancer: TP53
hsa04350__21	8.71307160116287e-05	DOWN	-3.92446273828898	0.000122543873791804	TGF-beta signaling pathway: CDKN2B
hsa04066__30	9.09411417046507e-05	UP	3.91414425606736	0.000127807333779386	HIF-1 signaling pathway: PDK1
hsa05133__60	9.26847123011575e-05	DOWN	-3.90955826396886	0.000130160369517096	Pertussis: C5
hsa05212__29	9.31255121087984e-05	UP	3.90841176594424	0.000130681730584341	Pancreatic cancer: VEGFA
hsa04152__58	9.53593680789271e-05	UP	3.90267927582112	0.000133716606433063	AMPK signaling pathway: SCD
hsa04921__60	9.99797410026547e-05	UP	3.89121429557487	0.000140090927176725	Oxytocin signaling pathway: ELK1
hsa05200__226	0.000101406550513409	DOWN	-3.887774801501	0.000141984283468477	Pathways in cancer: CDKN1A*
hsa04620__21	0.00010236841120828	UP	3.88548180545175	0.000143224307267579	Toll-like receptor signaling pathway: IFNA1
hsa03320__20	0.000116225863945105	DOWN	-3.8545263587869	0.000162370556396173	PPAR signaling pathway: SCP2
hsa04910__32	0.000116225863945105	DOWN	-3.8545263587869	0.000162370556396173	Insulin signaling pathway: EIF4E
hsa04024__34	0.000117319783147868	UP	3.85223336273765	0.000163777022685619	cAMP signaling pathway: ATP2B1
hsa05161__92	0.000146000931105538	DOWN	-3.7983479555803	0.000203664253561475	Hepatitis B: NFKBIA
hsa04740__33	0.00014872497574228	DOWN	-3.79376196348181	0.000207310259213461	Olfactory transduction: CNGA3*
hsa04932__55	0.000156465169305199	UP	3.78115048521094	0.000217937771033705	Non-alcoholic fatty liver disease (NAFLD): CASP3
hsa05221__5	0.000176293560423347	DOWN	-3.75134153657071	0.000245374518544792	Acute myeloid leukemia: SPI1
hsa04024__91	0.000179546139744842	DOWN	-3.74675554447221	0.000249531950133549	cAMP signaling pathway: GRIA1
hsa04550__101	0.000179546139744842	DOWN	-3.74675554447221	0.000249531950133549	Signaling pathways regulating pluripotency of stem cells: ESRRB
hsa05210__23	0.000202102878250984	DOWN	-3.71694659583198	0.000280673546366297	Colorectal cancer: CCND1
hsa05034__62	0.000205800852515251	DOWN	-3.71236060373348	0.000285598081149303	Alcoholism: NPY
hsa05162__27 70	0.000212425678470166	DOWN	-3.70433511756111	0.000294574058926525	Measles: STAT1 GNB2L1
hsa04728__61	0.000219250378788417	DOWN	-3.69630963138874	0.000303813762347666	Dopaminergic synapse: KCNJ3
hsa04666__40	0.000225263429637076	DOWN	-3.689430643241	0.00031191597957853	Fc gamma R-mediated phagocytosis: PLA2G6
hsa04360__18	0.000233521853549144	DOWN	-3.680258659044	0.000323113080131695	Axon guidance: PTK2
hsa04068__72	0.0002356304060406	DOWN	-3.67796566299475	0.000325790679139284	FoxO signaling pathway: SMAD2
hsa05211__21	0.000238826756587221	DOWN	-3.67452616892088	0.000329967261490726	Renal cell carcinoma: TGFB1*
hsa04724__67	0.000242063754181179	DOWN	-3.67108667484701	0.000334193823737278	Glutamatergic synapse: PLD1
hsa04064__36	0.000257721373500368	DOWN	-3.65503570250227	0.000355549530695442	NF-kappa B signaling pathway: PLCG1
hsa04722__53	0.000258875361240051	DOWN	-3.65388920447764	0.000356879533213541	Neurotrophin signaling pathway: JUN
hsa04014__97	0.000270684762634556	UP	3.6424242242314	0.000372886120960652	Ras signaling pathway: PAK4
hsa05221__6	0.000273106442229281	UP	3.64013122818215	0.000375946523772029	Acute myeloid leukemia: CEBPA
hsa04540__21	0.000274324882731308	DOWN	-3.63898473015753	0.000377347331370518	Gap junction: C03758
hsa04210__102	0.00028174317518081	DOWN	-3.63210574200978	0.000387268051327536	Apoptosis: PIDD1
hsa05161__126	0.000299789860826316	UP	3.61605476966504	0.00041177276936597	Hepatitis B: MYC*
hsa04668__102	0.00030649340169635	DOWN	-3.61032227954192	0.000420672828186591	TNF signaling pathway: AKT3
hsa05223__8	0.000321738361510067	DOWN	-3.59771080127105	0.000441274730859427	Non-small cell lung cancer: CASP9
hsa04930__13	0.000333268287856716	DOWN	-3.58853881707406	0.00045675500574965	Type II diabetes mellitus: C00162
hsa05210__22	0.000336210584024749	UP	3.58624582102481	0.000460451667188414	Colorectal cancer: MYC
hsa05200__75	0.000351290146346775	DOWN	-3.57478084077857	0.000480753230142455	Pathways in cancer: MAPK8
hsa04152__53	0.00036063911712532	DOWN	-3.56790185263082	0.000493188428732516	AMPK signaling pathway: G6PC
hsa04024__110	0.000375099709403866	DOWN	-3.5575833704092	0.000512590802887173	cAMP signaling pathway: FOS
hsa04724__52	0.000396946459144849	UP	3.54267889608909	0.000541657513967444	Glutamatergic synapse: CACNA1A
hsa05212__12	0.000396946459144849	DOWN	-3.54267889608909	0.000541657513967444	Pancreatic cancer: CASP9
hsa05217__3	0.000403904122475548	UP	3.53809290399059	0.000550751702562812	Basal cell carcinoma: GLI1
hsa05221__26	0.000446172226700621	UP	3.51172344942423	0.000607946057991636	Acute myeloid leukemia: BAD
hsa04650__40	0.000448100454574506	DOWN	-3.51057695139961	0.000610130981264853	Natural killer cell mediated cytotoxicity: TNFRSF10D
hsa04726__41	0.000453931904869933	DOWN	-3.50713745732573	0.000617176591353548	Serotonergic synapse: HTR3C
hsa04742__57	0.000453931904869933	DOWN	-3.50713745732573	0.000617176591353548	Taste transduction: HTR3C
hsa04310__13	0.000461817375519615	UP	3.50255146522724	0.000627443852929398	Wnt signaling pathway: NFATC1
hsa04014__35	0.000465807866649758	DOWN	-3.50025846917799	0.000632408223580127	Ras signaling pathway: NFKB1
hsa04662__27	0.000475925278043963	UP	3.49452597905487	0.000645677687685637	B cell receptor signaling pathway: NFATC1
hsa05160__22 23	0.000477973201929179	DOWN	-3.49337948103024	0.000647988200883786	Hepatitis C: STAT1 IRF9
hsa05161__29	0.000507520861937825	DOWN	-3.4773285086855	0.000687549891550954	Hepatitis B: NFKB1
hsa04728__71 72	0.000538764277678245	UP	3.46127753634076	0.000729350200113416	Dopaminergic synapse: CLOCK ARNTL
hsa03320__27	0.000543371179437205	DOWN	-3.45898454029151	0.000734528378534179	PPAR signaling pathway: CPT1C
hsa04020__7	0.000543371179437205	UP	3.45898454029151	0.000734528378534179	Calcium signaling pathway: ADCY1
hsa04911__54	0.000576661587655633	UP	3.44293356794677	0.000778969894467962	Insulin secretion: RAB3A
hsa04390__80	0.00058156950311608	DOWN	-3.44064057189752	0.000785035270370053	Hippo signaling pathway: BIRC2
hsa04064__136	0.000591502216647993	DOWN	-3.43605457979903	0.000797869824179167	NF-kappa B signaling pathway: TNFSF13B*
hsa04064__54	0.000601592659962286	DOWN	-3.43146858770053	0.000810898571068246	NF-kappa B signaling pathway: CCL13
hsa05169__118	0.000614431011778024	UP	3.42573609757741	0.000827609943463015	Epstein-Barr virus infection: MDM2
hsa05205__69	0.00063283340790176	DOWN	-3.41771061140504	0.000851786513930807	Proteoglycans in cancer: MAPK1*
hsa05169__60	0.000679680865655972	DOWN	-3.39822014498642	0.000914187792818591	Epstein-Barr virus infection: NFKB1
hsa05205__236	0.00068253458142162	DOWN	-3.3970736469618	0.000917369440980846	Proteoglycans in cancer: ITGAV
hsa04213__13	0.000694061184368275	UP	3.3924876548633	0.00093219511467333	Longevity regulating pathway - multiple species: RPS6KB1*
hsa04066__49	0.00073584434603715	DOWN	-3.37643668251856	0.000987608233002718	HIF-1 signaling pathway: EPO
hsa05168__138	0.000738916517661761	UP	3.37529018449394	0.000991023652167345	Herpes simplex infection: CHUK
hsa05014__33 34	0.000793000360050551	DOWN	-3.35579971807533	0.00106280148112338	Amyotrophic lateral sclerosis (ALS): NEFH PRPH
hsa04115__55	0.000802917749223952	UP	3.35236022400145	0.00107532605188297	p53 signaling pathway: SHISA5
hsa05219__19	0.000809593152676302	DOWN	-3.3500672279522	0.00108349396999912	Bladder cancer: TP53
hsa05205__304	0.000833364742875359	DOWN	-3.34204174177983	0.00111451412943972	Proteoglycans in cancer: MAPK1*****
hsa05231__48	0.000843749431546087	DOWN	-3.33860224770596	0.00112759970261387	Choline metabolism in cancer: WAS
hsa04917__38	0.000962238351147088	DOWN	-3.30191431091798	0.00128503614911541	Prolactin signaling pathway: IRF1
hsa04976__41	0.000974102107923594	UP	3.29847481684411	0.00129995586703724	Bile secretion: CYP7A1
hsa04726__45	0.000982081914261042	DOWN	-3.29618182079486	0.00130875343857234	Serotonergic synapse: TRPC1
hsa04071__57	0.000982087465879194	UP	3.29618182079486	0.00130875343857234	Sphingolipid signaling pathway: BAX
hsa05034__99	0.000986102507354408	DOWN	-3.29503532277024	0.00131317265153716	Alcoholism: PDYN
hsa04024__44 67	0.00100231513448446	UP	3.29044933067174	0.00133193079045	cAMP signaling pathway: CREB3 CREBBP
hsa05200__5	0.00100231513448446	DOWN	-3.29044933067174	0.00133193079045	Pathways in cancer: CASP3*
hsa05210__7	0.00100231513448446	DOWN	-3.29044933067174	0.00133193079045	Colorectal cancer: CASP3*
hsa04210__106	0.00101463615897595	UP	3.28700983659787	0.00134735077223732	Apoptosis: TUBA1B
hsa05200__193	0.00104818090166428	DOWN	-3.27783785240087	0.00139091236880451	Pathways in cancer: NOS2
hsa04390__94	0.00111385845956109	UP	3.26064038203151	0.00147702190932624	Hippo signaling pathway: GLI2
hsa05200__183	0.00117383552334014	UP	3.24573590771139	0.00155545624002547	Pathways in cancer: BMP2
hsa05130__55	0.00121709133788542	UP	3.23541742548977	0.00161163821274609	Pathogenic Escherichia coli infection: ACTB
hsa04623__17	0.00124674145281635	DOWN	-3.22853843734203	0.00164973745763516	Cytosolic DNA-sensing pathway: NFKB1
hsa04668__20	0.00125174750279852	DOWN	-3.2273919393174	0.00165519602938665	TNF signaling pathway: IKBKG
hsa04919__84	0.00130283880709855	UP	3.21592695907116	0.00172154298068788	Thyroid hormone signaling pathway: TP53*
hsa04932__31 133	0.00132380474293359	UP	3.21134096697266	0.00174801764720465	Non-alcoholic fatty liver disease (NAFLD): PPARA RXRA
hsa05222__34	0.00133441038869472	DOWN	-3.20904797092341	0.001760784494633	Small cell lung cancer: CCND1
hsa04350__50	0.00134509012426545	DOWN	-3.20675497487417	0.00177238733765413	TGF-beta signaling pathway: AMHR2
hsa04961__26	0.00134509012426545	DOWN	-3.20675497487417	0.00177238733765413	Endocrine and other factor-regulated calcium reabsorption: TRPV5*
hsa04550__36	0.0013558486639959	DOWN	-3.20446197882492	0.00178531159050336	Signaling pathways regulating pluripotency of stem cells: AKT3*
hsa05152__6	0.00139968140005559	DOWN	-3.19528999462792	0.00184173764054933	Tuberculosis: IL10
hsa04662__16	0.00154521948392562	UP	3.16662754401232	0.00203181764191479	B cell receptor signaling pathway: VAV3
hsa04750__90	0.00163268605703944	DOWN	-3.15057657166758	0.00214532664417979	Inflammatory mediator regulation of TRP channels: C01245**
hsa05162__81	0.00168469021366841	DOWN	-3.14140458747058	0.00221211244687836	Measles: TNFRSF10D
hsa05205__415	0.00169129679337613	UP	3.14025808944596	0.00221923650471631	Proteoglycans in cancer: MAPK1******
hsa04071__1	0.00171125978643429	DOWN	-3.13681859537208	0.00224386401863924	Sphingolipid signaling pathway: MAPK1
hsa05145__10	0.00171796212670398	UP	3.13567209734746	0.00225108147564629	Toxoplasmosis: MAPK8
hsa05168__29	0.00177937863446319	UP	3.12535361512584	0.00232993202380232	Herpes simplex infection: IKBKG
hsa04919__38	0.00182143742078927	DOWN	-3.1184746269781	0.00238334325464	Thyroid hormone signaling pathway: TP53
hsa04370__38	0.00184998209062949	UP	3.1138886348796	0.00241900928899987	VEGF signaling pathway: BAD
hsa05014__54	0.00192315116174404	UP	3.10242365463336	0.00250944516174795	Amyotrophic lateral sclerosis (ALS): PPP3CA
hsa05164__70	0.00192315116174404	DOWN	-3.10242365463336	0.00250944516174795	Influenza A: RNASEL
hsa05168__83	0.00192315116174404	DOWN	-3.10242365463336	0.00250944516174795	Herpes simplex infection: RNASEL
hsa04115__30	0.00193810013670736	UP	3.10013065858411	0.00252719650025894	p53 signaling pathway: SERPINE1
hsa04920__3	0.00196831864198577	DOWN	-3.09554466648561	0.00256482019992459	Adipocytokine signaling pathway: C15493
hsa05220__6	0.00197594054809407	UP	3.09439816846098	0.00257296762984668	Chronic myeloid leukemia: TP53
hsa04151__33	0.00199126569663342	UP	3.09210517241174	0.00259112759277991	PI3K-Akt signaling pathway: TP53
hsa05169__64	0.00199896911159311	DOWN	-3.09095867438711	0.00259935152988475	Epstein-Barr virus infection: NFKB2
hsa04012__29	0.00203789806502695	DOWN	-3.08522618426399	0.00264814001672589	ErbB signaling pathway: STAT5A*
hsa04530__7 52	0.00217551782302503	DOWN	-3.06573571784538	0.00282501588767384	Tight junction: PARD6A MPP5
hsa05166__83	0.00220911335323307	DOWN	-3.06114972574688	0.00286666021458905	HTLV-I infection: NFKB2
hsa04015__27	0.00223462130373847	DOWN	-3.05771023167301	0.00289775944080372	Rap1 signaling pathway: RALA
hsa03320__56	0.00231277312974204	UP	3.04739174945139	0.00299290682560971	PPAR signaling pathway: FADS2
hsa05200__225	0.00231277312974204	DOWN	-3.04739174945139	0.00299290682560971	Pathways in cancer: PPARD
hsa05221__11	0.00231277312974204	DOWN	-3.04739174945139	0.00299290682560971	Acute myeloid leukemia: PPARD
hsa05145__23	0.00232160945781714	DOWN	-3.04624525142676	0.00300227403388741	Toxoplasmosis: CIITA
hsa05212__14	0.00233047669501602	UP	3.04509875340214	0.00301166830119333	Pancreatic cancer: MAPK1
hsa04014__45	0.00238433462738348	UP	3.03821976525439	0.00307703623959723	Ras signaling pathway: RAB5A
hsa04668__128	0.00238433462738348	DOWN	-3.03821976525439	0.00307703623959723	TNF signaling pathway: CHUK*
hsa04024__109	0.0024208704086451	DOWN	-3.0336337731559	0.00312204220854093	cAMP signaling pathway: BDNF
hsa04360__58	0.00248604325303464	DOWN	-3.02560828698353	0.00320389250511117	Axon guidance: PLXNC1
hsa04722__38	0.00253357381763009	DOWN	-3.01987579686041	0.00326290966643382	Neurotrophin signaling pathway: ATF4
hsa04917__57	0.00261135410041006	DOWN	-3.01070381266341	0.00336077695525377	Prolactin signaling pathway: ESR1
hsa04360__125	0.00265105738910625	UP	3.00611782056491	0.00340953924307368	Axon guidance: ENAH*
hsa04917__68	0.00267111524863794	DOWN	-3.00382482451566	0.00342829614220675	Prolactin signaling pathway: CCND1
hsa04924__58	0.00267111524863794	DOWN	-3.00382482451566	0.00342829614220675	Renin secretion: PPP3CA
hsa05031__59	0.00267111524863794	DOWN	-3.00382482451566	0.00342829614220675	Amphetamine addiction: PPP3CA
hsa04115__3	0.0027735006890634	DOWN	-2.99235984426942	0.00355727494522193	p53 signaling pathway: GADD45G
hsa04917__56	0.00282602637847972	DOWN	-2.9866273541463	0.00362217159970218	Prolactin signaling pathway: LHCGR
hsa05200__80	0.00287945891459239	UP	2.98089486402318	0.00368814130914731	Pathways in cancer: TP53
hsa05133__59	0.00290108894711919	UP	2.97860186797393	0.00371331480356741	Pertussis: C3
hsa05200__146 147	0.00291195547772302	UP	2.97745536994931	0.0037196222587638	Pathways in cancer: RARB RXRA
hsa05222__14 15	0.00291195547772302	UP	2.97745536994931	0.0037196222587638	Small cell lung cancer: RXRA RARB
hsa05223__29 34	0.00291195547772302	UP	2.97745536994931	0.0037196222587638	Non-small cell lung cancer: RARB RXRA
hsa04976__95 96	0.00292276508611134	DOWN	-2.97630887192468	0.00373089374782827	Bile secretion: SLC51A SLC51B
hsa04115__15	0.00294479453759541	UP	2.97401587587543	0.00375646227843977	p53 signaling pathway: TSC2
hsa04730__7	0.00297796712115107	DOWN	-2.97057638180156	0.00379620096380112	Long-term depression: GNA13
hsa05205__121	0.00312569079479842	UP	2.95567190748144	0.0039818122057127	Proteoglycans in cancer: PLAUR
hsa04921__43	0.0032922241650746	DOWN	-2.9396209351367	0.00419111734835717	Oxytocin signaling pathway: CACNG3
hsa04550__67	0.00335363238165709	UP	2.93388844501358	0.00426640165547303	Signaling pathways regulating pluripotency of stem cells: MYC*
hsa04115__56	0.00342869814959162	UP	2.92700945686584	0.00435894710628054	p53 signaling pathway: SESN3
hsa04210__61	0.00346680175282748	DOWN	-2.92356996279196	0.00440143276592084	Apoptosis: APAF1
hsa05152__81	0.00346680175282748	DOWN	-2.92356996279196	0.00440143276592084	Tuberculosis: IFNA1
hsa04919__29	0.00378578234995756	DOWN	-2.89605401020098	0.00480316342712374	Thyroid hormone signaling pathway: HIF1A
hsa04919__87	0.00382747669656173	UP	2.89261451612711	0.00485278590609952	Thyroid hormone signaling pathway: BAD
hsa04930__26	0.00388371816144367	UP	2.88802852402861	0.00492077304474218	Type II diabetes mellitus: INS*
hsa05205__146	0.00391211948179069	DOWN	-2.88573552797936	0.00495341813091962	Proteoglycans in cancer: PTK2
hsa03320__66	0.00392639076700891	DOWN	-2.88458902995474	0.00496479693890292	PPAR signaling pathway: UCP1
hsa04340__50	0.00392639076700891	DOWN	-2.88458902995474	0.00496479693890292	Hedgehog signaling pathway: BCL2
hsa05014__32 34	0.00394070931858953	DOWN	-2.88344253193011	0.0049795513178411	Amyotrophic lateral sclerosis (ALS): NEFM PRPH
hsa04014__27	0.00404227424320053	UP	2.87541704575774	0.00510445786490174	Ras signaling pathway: ABL1
hsa05164__99	0.00408652493427858	UP	2.87197755168387	0.00515687061887807	Influenza A: FDPS
hsa04920__10	0.00414620970434954	DOWN	-2.86739155958537	0.00522867653320321	Adipocytokine signaling pathway: PCK1
hsa05142__53	0.00416125395716307	UP	2.86624506156075	0.00524412889705528	Chagas disease (American trypanosomiasis): AKT3
hsa04152__81	0.0042066843419086	UP	2.86280556748688	0.00529427989179254	AMPK signaling pathway: LIPE
hsa04914__42	0.0042066843419086	UP	2.86280556748688	0.00529427989179254	Progesterone-mediated oocyte maturation: ARAF
hsa04210__4	0.00439293954054256	UP	2.84904759119138	0.00552498888666631	Apoptosis: DFFA
hsa04724__3	0.00461966375782446	DOWN	-2.83299661884664	0.00580237179208032	Glutamatergic synapse: GRIK1
hsa04750__39	0.00461966375782446	DOWN	-2.83299661884664	0.00580237179208032	Inflammatory mediator regulation of TRP channels: C01245*
hsa04150__56	0.00463625688954112	DOWN	-2.83185012082202	0.00581932310985154	mTOR signaling pathway: EIF4B
hsa04210__51	0.00473695400693305	UP	2.82497113267427	0.00594174671497143	Apoptosis: LMNA
hsa04976__38	0.00483962669027466	DOWN	-2.81809214452653	0.00606648335625489	Bile secretion: ABCC2
hsa05014__31 34	0.00512333740739817	DOWN	-2.79974817613254	0.00641783399233411	Amyotrophic lateral sclerosis (ALS): NEFL PRPH
hsa05200__196	0.00514155869801559	DOWN	-2.79860167810792	0.00643636828352518	Pathways in cancer: TRAF1
hsa05213__13	0.00521503096793451	DOWN	-2.79401568600942	0.00652399679677027	Endometrial cancer: CASP9
hsa04742__18	0.00546041323598278	DOWN	-2.7791112116893	0.0068264247973464	Taste transduction: PDE1A
hsa05030__80 81	0.00553798536560165	UP	2.77452521959081	0.00691879953588131	Cocaine addiction: GRIN3A DLG4
hsa04350__34	0.00563634839686869	DOWN	-2.76879272946768	0.00703700906160549	TGF-beta signaling pathway: ROCK1
hsa04919__104	0.0056562091098876	DOWN	-2.76764623144306	0.00705711614706428	Thyroid hormone signaling pathway: MYC
hsa04012__25	0.00598268248848683	UP	2.74930226304907	0.00745949594948027	ErbB signaling pathway: CDKN1B
hsa04151__97	0.00610942291508207	DOWN	-2.74242327490132	0.00760742588299484	PI3K-Akt signaling pathway: MCL1
hsa04920__6	0.00610942291508207	DOWN	-2.74242327490132	0.00760742588299484	Adipocytokine signaling pathway: PTPN11
hsa05205__142	0.00615220402807284	DOWN	-2.74013027885208	0.0076556234230125	Proteoglycans in cancer: CTNNB1
hsa05140__26	0.00668703055569565	DOWN	-2.71261432626109	0.00831563892399214	Leishmaniasis: C00533
hsa04015__11	0.00687438143868229	DOWN	-2.7034423420641	0.00854296476407674	Rap1 signaling pathway: RAC1
hsa04380__51	0.00706643489221136	DOWN	-2.6942703578671	0.00877583024617657	Osteoclast differentiation: FOS*
hsa04724__13	0.00709075291115243	UP	2.69312385984248	0.00879443595313241	Glutamatergic synapse: GRM5
hsa04662__35	0.00709077725864588	DOWN	-2.69312385984248	0.00879443595313241	B cell receptor signaling pathway: CD79B
hsa04068__88	0.00711519488615948	DOWN	-2.69197736181786	0.00881889920256838	FoxO signaling pathway: FBXO32
hsa03320__42	0.00731326945304559	DOWN	-2.68280537762086	0.00905842669892726	PPAR signaling pathway: ACOX1
hsa04931__35	0.00777713533023493	DOWN	-2.66216841317762	0.00962663852800489	Insulin resistance: C00369
hsa04921__11	0.0079375162400893	DOWN	-2.65528942502988	0.00981869191252653	Oxytocin signaling pathway: PRKACA
hsa04014__63	0.00799163108321311	DOWN	-2.65299642898063	0.00987912816141936	Ras signaling pathway: TIAM1*
hsa04211__57	0.0080734228788823	DOWN	-2.64955693490676	0.00997367625865867	Longevity regulating pathway - mammal: ATG5
hsa05213__31	0.00849372906920157	DOWN	-2.63235946453739	0.0104860163738697	Endometrial cancer: MYC
hsa04330__12	0.00872580108806971	DOWN	-2.6231874803404	0.0107654499307177	Notch signaling pathway: HES1
hsa04270__28	0.00887370786818177	UP	2.61745499021728	0.010940746118316	Vascular smooth muscle contraction: KCNMB2
hsa05145__4 5	0.00905414939991967	DOWN	-2.61057600206953	0.0111558994901305	Toxoplasmosis: MAP3K7 TAB1
hsa04622__9 35	0.00914559287805383	UP	2.60713650799566	0.0112611854638684	RIG-I-like receptor signaling pathway: IRF3 PIN1
hsa04066__53	0.00942488960583614	DOWN	-2.59681802577404	0.0115974902222437	HIF-1 signaling pathway: EGF*
hsa05215__13	0.00974412075404444	DOWN	-2.5853530455278	0.0119824626288282	Prostate cancer: BCL2
hsa04390__96	0.00984175140606474	DOWN	-2.58191355145392	0.0120946048999317	Hippo signaling pathway: FGF1
hsa05219__12	0.0102072297816201	UP	2.56930207318306	0.0125355455945517	Bladder cancer: ERBB2
hsa03320__41	0.0106546990985748	UP	2.55439759886294	0.0130765379531169	PPAR signaling pathway: ANGPTL4
hsa04014__43	0.0106898317429347	UP	2.55325110083832	0.0131110925881034	Ras signaling pathway: ELK1
hsa04620__22	0.0107250673584961	DOWN	-2.55210460281369	0.0131457283539557	Toll-like receptor signaling pathway: CD86
hsa04510__43	0.0109027989582376	DOWN	-2.54637211269057	0.0133548626092102	Focal adhesion: BAD
hsa04390__76	0.0111926175754843	DOWN	-2.53720012849358	0.0137009305695993	Hippo signaling pathway: MYC
hsa05161__26	0.0113772099261685	DOWN	-2.53146763837045	0.0139087686735658	Hepatitis B: MMP9
hsa05168__27	0.0113772099261685	DOWN	-2.53146763837045	0.0139087686735658	Herpes simplex infection: IRF3
hsa04152__52	0.0114144510558064	DOWN	-2.53032114034583	0.0139452233640183	AMPK signaling pathway: PCK1
hsa05131__12	0.0114518003545669	UP	2.5291746423212	0.0139817627460891	Shigellosis: ARPC5
hsa04010__87	0.0117162964978795	DOWN	-2.52114915614884	0.0142954033243608	MAPK signaling pathway: STK3
hsa05217__10	0.0121035469220768	UP	2.50968417590259	0.0147583158121884	Basal cell carcinoma: PTCH1*
hsa04064__93	0.0125020989969107	UP	2.49821919565635	0.0152343994910475	NF-kappa B signaling pathway: PLAU
hsa04917__48	0.0126647459295428	DOWN	-2.49363320355785	0.0154225907981924	Prolactin signaling pathway: CCND2
hsa05222__39	0.012870686720546	DOWN	-2.48790071343473	0.0156632256139287	Small cell lung cancer: BCL2L1
hsa04115__25	0.0130375670171376	UP	2.48331472133623	0.0158560442881564	p53 signaling pathway: CD82
hsa04722__33	0.013206358239628	UP	2.47872872923774	0.016050936049328	Neurotrophin signaling pathway: BAD
hsa05164__23	0.0138124412908436	UP	2.462677756893	0.0167767144056206	Influenza A: IRF3
hsa05016__22 9	0.0142149162676891	UP	2.45235927467138	0.017254410637589	Huntington's disease: DLG4 HTT
hsa04650__35	0.0144889482912595	UP	2.44548028652363	0.0175756835631223	Natural killer cell mediated cytotoxicity: BID
hsa04210__105	0.0146742143712684	UP	2.44089429442513	0.0177889347120086	Apoptosis: ACTB
hsa04510__44	0.0150987160533429	UP	2.43057581220352	0.0182917391774541	Focal adhesion: BCL2
hsa04730__8	0.0155830357103629	DOWN	-2.41911083195727	0.0188663170745953	Long-term depression: GNA13*
hsa05205__113	0.0156322114562437	UP	2.41796433393265	0.0189136673060411	Proteoglycans in cancer: TP53
hsa05215__35	0.016182221712014	DOWN	-2.40535285566178	0.0195665344896231	Prostate cancer: CASP9
hsa04068__49	0.0174416163451597	DOWN	-2.3778369030708	0.0210757537701319	FoxO signaling pathway: BCL2L11
hsa04213__55	0.0179912249595478	DOWN	-2.36637192282455	0.0217259072615619	Longevity regulating pathway - multiple species: CRYAB
hsa05161__78	0.0184987832811343	DOWN	-2.35605344060294	0.0223244789886007	Hepatitis B: TNF
hsa04022__19	0.0186132610484423	UP	2.35376044455369	0.022448214062916	cGMP-PKG signaling pathway: CNGB1
hsa04742__67	0.0190773933253594	UP	2.34458846035669	0.0229784756784297	Taste transduction: PRKACA
hsa05142__64	0.0190773933253594	DOWN	-2.34458846035669	0.0229784756784297	Chagas disease (American trypanosomiasis): CASP8
hsa05210__16	0.0193132307879834	DOWN	-2.3400024682582	0.0232476365474829	Colorectal cancer: MAPK8
hsa04620__19	0.0203441908120931	UP	2.32051200183958	0.0244729414442529	Toll-like receptor signaling pathway: CXCL10
hsa04152__56	0.0205310248625345	UP	2.31707250776571	0.0246818910535524	AMPK signaling pathway: FASN
hsa05205__400	0.0205936309361261	DOWN	-2.31592600974109	0.0247255203023293	Proteoglycans in cancer: ITGA2*
hsa05200__48	0.0205936345253568	UP	2.31592600974109	0.0247255203023293	Pathways in cancer: MTOR
hsa05014__51	0.021552952326876	DOWN	-2.29872853937172	0.0258607901802043	Amyotrophic lateral sclerosis (ALS): DERL1
hsa05010__51	0.0216837562521146	UP	2.29643554332247	0.0260011346507488	Alzheimer's disease: ATF6
hsa04024__60	0.0231688200539223	UP	2.27121258678074	0.0277641663783929	cAMP signaling pathway: PDE3A
hsa04630__33	0.0258659206087997	UP	2.22879215986964	0.030976459416147	Jak-STAT signaling pathway: RAF1
hsa04150__33	0.0264056404703609	DOWN	-2.22076667369727	0.0316026741680306	mTOR signaling pathway: RPS6
hsa05020__46	0.0265616222862406	UP	2.21847367764802	0.0317691204811242	Prion diseases: PRKACA
hsa05200__49	0.0267183993892102	DOWN	-2.21618068159877	0.0319363056312506	Pathways in cancer: CASP9
hsa04919__31	0.0274338247242915	DOWN	-2.20586219937715	0.0327706018162388	Thyroid hormone signaling pathway: ATP2A2
hsa04022__23	0.0278383791690549	DOWN	-2.20012970925403	0.0332327283727155	cGMP-PKG signaling pathway: CACNA1C
hsa05120__50	0.0289143731459046	DOWN	-2.18522523493391	0.0344953061213681	Epithelial cell signaling in Helicobacter pylori infection: EGFR
hsa04210__64	0.0296800980165142	DOWN	-2.1749067527123	0.0353863605158821	Apoptosis: TNFRSF10D*
hsa05020__59	0.0297662453842682	DOWN	-2.17376025468767	0.0354665663139124	Prion diseases: CCL5
hsa04742__55	0.029937835850894	DOWN	-2.17146725863842	0.035648411637408	Taste transduction: P2RX3
hsa04912__26	0.0313540584594813	DOWN	-2.15312329024443	0.0373111309976982	GnRH signaling pathway: PLD1
hsa04151__63	0.0314443617742753	DOWN	-2.15197679221981	0.0373949087176349	PI3K-Akt signaling pathway: CASP9
hsa04210__31 32 33	0.0316256378810819	DOWN	-2.14968379617056	0.0375867005556944	Apoptosis: TRAF2 RIPK1 TRADD
hsa04620__48	0.0323597321116453	DOWN	-2.14051181197357	0.038434852489116	Toll-like receptor signaling pathway: CD80
hsa04390__18	0.0335837685765296	DOWN	-2.12560733765345	0.0398634877797215	Hippo signaling pathway: MOB1A
hsa04932__7	0.0343565372599234	DOWN	-2.11643535345646	0.0407550085299217	Non-alcoholic fatty liver disease (NAFLD): SREBF1
hsa04510__6 4 5	0.0347485860271043	UP	2.11184936135796	0.0411680915163487	Focal adhesion: FLNA ITGB1 ITGA11
hsa04742__48	0.0347485860271043	UP	2.11184936135796	0.0411680915163487	Taste transduction: GABBR1
hsa04115__37	0.0374961305304349	DOWN	-2.0808939146931	0.044395229531624	p53 signaling pathway: FAS
hsa04210__60	0.0377068107265555	UP	2.07860091864386	0.0446165600473538	Apoptosis: BBC3
hsa04072__27	0.0400915212639899	DOWN	-2.05337796210212	0.0473785965126019	Phospholipase D signaling pathway: C01245
hsa04510__26 4 5	0.0400915212639899	UP	2.05337796210212	0.0473785965126019	Focal adhesion: ACTN4 ITGB1 ITGA11
hsa04668__47	0.0402028902861778	DOWN	-2.0522314640775	0.047480346227359	TNF signaling pathway: CASP7
hsa04742__49	0.041331083303309	DOWN	-2.04076648383125	0.0487821014616316	Taste transduction: HTR1A
hsa05150__40	0.0422528389510917	DOWN	-2.03159449963426	0.049838722152606	Staphylococcus aureus infection: FCGR1A
hsa04621__30 32	0.042602952510073	UP	2.02815500556039	0.0502201679839569	NOD-like receptor signaling pathway: PYCARD CASP1
hsa04913__12	0.0433105430925839	DOWN	-2.02127601741264	0.05102226361816	Ovarian steroidogenesis: HSD3B1
hsa04725__54	0.0445119220031838	UP	2.0098110371664	0.0524047001528712	Cholinergic synapse: CHRM1*
hsa04024__111	0.0484162805272996	DOWN	-1.97426959840304	0.0569656800944245	cAMP signaling pathway: JUN
hsa04650__36	0.0497355533584933	UP	1.9628046181568	0.0584812920904937	Natural killer cell mediated cytotoxicity: CASP3
hsa05169__79	0.0500029938004996	UP	1.96051162210755	0.0587589902133451	Epstein-Barr virus infection: ATF2
hsa05222__40	0.0502716388591698	UP	1.9582186260583	0.0590377558852376	Small cell lung cancer: TRAF1
hsa05321__123	0.0508125588599423	DOWN	-1.95363263395981	0.0596357264820935	Inflammatory bowel disease (IBD): IL5*
hsa04010__57	0.0537329818465923	DOWN	-1.9295561754427	0.0629845744789438	MAPK signaling pathway: NLK
hsa04360__6	0.0537329818465923	UP	1.9295561754427	0.0629845744789438	Axon guidance: MAPK1
hsa04620__12	0.0587576934538236	DOWN	-1.89057524260547	0.0688314875310066	Toll-like receptor signaling pathway: NFKB1
hsa04920__1	0.0609371761982552	UP	1.87452427026073	0.0713401583031287	Adipocytokine signaling pathway: C00195
hsa04930__9	0.0612538493726212	DOWN	-1.87223127421148	0.0716662409533968	Type II diabetes mellitus: C00238
hsa05220__22	0.0631832094603971	DOWN	-1.85847329791599	0.0738775672533206	Chronic myeloid leukemia: CDKN1B
hsa04622__5 33	0.063673298390298	DOWN	-1.85503380384212	0.0744043082558271	RIG-I-like receptor signaling pathway: MAVS TMEM173
hsa05166__39	0.0654972291271969	UP	1.84242232557125	0.076488063101307	HTLV-I infection: RRAS2
hsa05161__57	0.065665155868571	UP	1.84127582754663	0.0766365390540652	Hepatitis B: STAT3*
hsa04020__18	0.0687489504919264	DOWN	-1.82063886310339	0.0800863471632546	Calcium signaling pathway: C00002
hsa04020__17	0.0687489504919264	DOWN	-1.82063886310339	0.0800863471632546	Calcium signaling pathway: C00004
hsa04020__15	0.0687489504919264	DOWN	-1.82063886310339	0.0800863471632546	Calcium signaling pathway: C13051
hsa05215__9	0.0703350098665068	DOWN	-1.81032038088177	0.0818831992188143	Prostate cancer: CDKN1B
hsa04015__18	0.0717698692244115	UP	1.80114839668477	0.0833986297295419	Rap1 signaling pathway: CDH1
hsa05200__52	0.0717698692244115	DOWN	-1.80114839668477	0.0833986297295419	Pathways in cancer: CDKN1B
hsa05205__215 216	0.0717698692244115	DOWN	-1.80114839668477	0.0833986297295419	Proteoglycans in cancer: EIF4B RPS6
hsa05152__126	0.0724962417449309	DOWN	-1.79656240458628	0.0841906293193604	Tuberculosis: NOS2
hsa04923__31	0.0728616786402433	DOWN	-1.79426940853703	0.0845627511828396	Regulation of lipolysis in adipocytes: PRKACA*
hsa04723__46	0.0730449616137604	UP	1.7931229105124	0.0847231375754665	Retrograde endocannabinoid signaling: ADCY1
hsa04660__26	0.0734126592810254	DOWN	-1.79082991446316	0.0850970924053342	T cell receptor signaling pathway: GRB2
hsa05142__49	0.0735970750424932	DOWN	-1.78968341643853	0.0852582638747501	Chagas disease (American trypanosomiasis): ADCY1
hsa04950__21	0.0741525964466953	UP	1.78624392236466	0.085848877833235	Maturity onset diabetes of the young: PKLR
hsa04912__33	0.0747115402500322	DOWN	-1.78280442829079	0.0864427242178636	GnRH signaling pathway: ELK1
hsa03320__22	0.0791120218257567	DOWN	-1.75643497372443	0.0914778393911366	PPAR signaling pathway: ACADM
hsa04151__28	0.0804923882959124	UP	1.74840948755206	0.0930167266961989	PI3K-Akt signaling pathway: BCL2L11
hsa05161__68	0.0810899322977676	DOWN	-1.74496999347818	0.0936496513752338	Hepatitis B: JUN
hsa04921__80	0.0820938371052371	UP	1.73923750335506	0.0947508107621257	Oxytocin signaling pathway: KCNJ2
hsa05211__3	0.0835162125971699	DOWN	-1.73121201718269	0.0963333109085833	Renal cell carcinoma: VEGFA
hsa04931__67	0.0855826257065652	DOWN	-1.71974703693645	0.0986562906151141	Insulin resistance: IKBKB**
hsa04622__11	0.086000955153628	UP	1.7174540408872	0.0990777404866137	RIG-I-like receptor signaling pathway: IRF7
hsa05218__14	0.0868423545324395	UP	1.7128680487887	0.0999857746117977	Melanoma: BAD
hsa05145__67	0.0885450870439931	UP	1.70369606459171	0.101883783561337	Toxoplasmosis: BAD
hsa04620__77	0.0887598078521119	UP	1.70254956656708	0.102068346973145	Toll-like receptor signaling pathway: CXCL9
hsa05200__129 130	0.0902746266102605	DOWN	-1.69452408039471	0.103683388386723	Pathways in cancer: CTBP1 HDAC1
hsa05220__12 13	0.0902746266102605	DOWN	-1.69452408039471	0.103683388386723	Chronic myeloid leukemia: HDAC1 CTBP1
hsa05222__32	0.0922527429006588	DOWN	-1.6842055981731	0.105890594936065	Small cell lung cancer: BIRC8
hsa05162__28 34	0.0935907212714658	DOWN	-1.67732661002535	0.107360784657561	Measles: IRF9 STAT1
hsa04110__96 97	0.0942655240049496	UP	1.67388711595148	0.108068895427273	Cell cycle: TFDP1 E2F4
hsa04024__21	0.0947175554499109	UP	1.67159411990223	0.108520906518526	cAMP signaling pathway: AKT3
hsa04152__30	0.0960840789233287	UP	1.66471513175448	0.110019490735487	AMPK signaling pathway: ACACA
hsa04151__73	0.0974663356478731	DOWN	-1.65783614360674	0.111534253765136	PI3K-Akt signaling pathway: MAPK1
hsa04390__88	0.100515746594852	DOWN	-1.64293166928662	0.114953796623084	Hippo signaling pathway: ID1
hsa04210__56	0.102912806186845	UP	1.63146668904038	0.117623578360756	Apoptosis: BAX
hsa04210__24	0.103154991733691	DOWN	-1.63032019101575	0.117828710922556	Apoptosis: CASP10
hsa04010__14	0.10461763536173	UP	1.62344120286801	0.119426814607953	MAPK signaling pathway: MAPT
hsa04725__43	0.106096698907112	DOWN	-1.61656221472026	0.121041710532158	Cholinergic synapse: CREB3
hsa04520__4	0.10684242364776	DOWN	-1.61312272064639	0.121818515797416	Adherens junction: CTNND1
hsa04724__36	0.112438712959825	UP	1.58789976410466	0.128121492814743	Glutamatergic synapse: TRPC1
hsa04015__100 101 48	0.113219431460399	DOWN	-1.58446027003078	0.128932916190357	Rap1 signaling pathway: PRKCI PARD6A PARD3
hsa04913__35	0.113480617998891	UP	1.58331377200616	0.129152078267666	Ovarian steroidogenesis: HSD17B2
hsa05200__173	0.114793676751896	UP	1.57758128188304	0.130488396017431	Pathways in cancer: CCNA1
hsa05221__16	0.114793676751896	UP	1.57758128188304	0.130488396017431	Acute myeloid leukemia: CCNA1
hsa05214__23	0.116652005873911	DOWN	-1.56955579571067	0.132440555309413	Glioma: MAPK1
hsa05214__56	0.116652005873911	DOWN	-1.56955579571067	0.132440555309413	Glioma: MAPK1*
hsa04932__35	0.118533882609733	DOWN	-1.5615303095383	0.134495872840392	Non-alcoholic fatty liver disease (NAFLD): PRKAG2
hsa05161__97	0.119075911349667	UP	1.55923731348905	0.135029352701282	Hepatitis B: BCL2
hsa04710__5	0.119619880771124	UP	1.5569443174398	0.135482673881219	Circadian rhythm: RORA
hsa04915__58	0.119619880771124	UP	1.5569443174398	0.135482673881219	Estrogen signaling pathway: CREB3***
hsa05200__190	0.120988321554347	UP	1.55121182731668	0.136950033855794	Pathways in cancer: MYC*
hsa05161__69	0.12153911543713	UP	1.54891883126743	0.13749066701166	Hepatitis B: SMAD4
hsa05162__13	0.123761921303619	DOWN	-1.53974684707043	0.139920968790313	Measles: IRF7
hsa05160__85	0.125167206657735	UP	1.53401435694731	0.141424643000532	Hepatitis C: BAD
hsa04066__50	0.130620978692536	DOWN	-1.51223089447945	0.147498088319276	HIF-1 signaling pathway: TF
hsa04151__24	0.131205621762818	UP	1.5099378984302	0.148069287262664	PI3K-Akt signaling pathway: MYC
hsa04727__26	0.13356450267649	UP	1.50076591423321	0.150370102174431	GABAergic synapse: KCNJ6
hsa05032__81	0.13356450267649	UP	1.50076591423321	0.150370102174431	Morphine addiction: KCNJ6
hsa05032__91	0.13356450267649	UP	1.50076591423321	0.150370102174431	Morphine addiction: KCNJ6**
hsa05032__85	0.13356450267649	UP	1.50076591423321	0.150370102174431	Morphine addiction: KCNJ6*
hsa04010__107	0.135655324155554	DOWN	-1.49274042806084	0.152541205319142	MAPK signaling pathway: MAP3K2
hsa04151__96	0.135655324155554	DOWN	-1.49274042806084	0.152541205319142	PI3K-Akt signaling pathway: BCL2
hsa04950__30	0.137771334375278	UP	1.48471494188847	0.154827952925328	Maturity onset diabetes of the young: PAX6*
hsa04662__36	0.138685947803252	UP	1.4812754478146	0.15566959135144	B cell receptor signaling pathway: CD79A
hsa05100__15	0.138685947803252	UP	1.4812754478146	0.15566959135144	Bacterial invasion of epithelial cells: CTNNA1
hsa04932__14	0.140220687408258	UP	1.47554295769147	0.157298311426936	Non-alcoholic fatty liver disease (NAFLD): PKLR
hsa05161__214	0.142391229227073	UP	1.4675174715191	0.159637899592882	Hepatitis B: CDKN1B
hsa05200__204	0.144587475579853	DOWN	-1.45949198534673	0.162003498279394	Pathways in cancer: TGFB1*
hsa04930__3	0.150354121694405	DOWN	-1.4388550209035	0.168364359156011	Type II diabetes mellitus: SLC2A4
hsa05200__222	0.160352551695963	UP	1.40446008016477	0.179453510802093	Pathways in cancer: CASP9*
hsa04668__38	0.161036568988065	DOWN	-1.40216708411552	0.180111734005104	TNF signaling pathway: CEBPB
hsa04610__17	0.162411212631717	UP	1.39758109201702	0.181541147254608	Complement and coagulation cascades: PLG
hsa05132__48	0.163794691415536	UP	1.39299509991852	0.182978730778712	Salmonella infection: KLC3
hsa04728__36	0.164838115115938	DOWN	-1.38955560584465	0.184034948486541	Dopaminergic synapse: TH
hsa05221__29	0.165536506190522	DOWN	-1.3872626097954	0.18470492585035	Acute myeloid leukemia: RPS6KB1
hsa04390__95	0.169417505015007	UP	1.37465113152454	0.188923140607239	Hippo signaling pathway: AFP
hsa04742__4	0.173004540395721	UP	1.36318615127829	0.192808737487284	Taste transduction: TRPM5
hsa03320__62	0.174819174999421	UP	1.35745366115517	0.194715607483054	PPAR signaling pathway: UBC
hsa05152__112	0.177015526105094	DOWN	-1.35057467300743	0.197045126511536	Tuberculosis: IFNGR1
hsa04666__49	0.182596147952328	DOWN	-1.33337720263806	0.203136863234117	Fc gamma R-mediated phagocytosis: ARF6*
hsa05321__138	0.188691455484382	UP	1.31503323424407	0.209793636008967	Inflammatory bowel disease (IBD): IFNG**
hsa04917__47	0.189077335657395	DOWN	-1.31388673621945	0.210098352276904	Prolactin signaling pathway: INS
hsa04913__64	0.189850840756024	DOWN	-1.3115937401702	0.210833173629178	Ovarian steroidogenesis: PLA2G4B
hsa04024__59	0.194935517623353	DOWN	-1.29668926585008	0.216351941886757	cAMP signaling pathway: MLLT4
hsa04950__8	0.195726559041559	DOWN	-1.29439626980083	0.21710165551304	Maturity onset diabetes of the young: NEUROD1
hsa04931__40	0.196519950750509	UP	1.29210327375159	0.217853089947024	Insulin resistance: PRKCZ
hsa05205__431	0.197714451227672	UP	1.28866377967771	0.219048027038205	Proteoglycans in cancer: CDKN1A*
hsa04151__103	0.198513730873602	DOWN	-1.28637078362846	0.219803948327341	PI3K-Akt signaling pathway: BCL2*
hsa04910__17	0.199717076228604	DOWN	-1.28293128955459	0.221006116745316	Insulin signaling pathway: C00031
hsa04071__59 60	0.207049170256508	DOWN	-1.26229432511135	0.228984926964084	Sphingolipid signaling pathway: TP53 BCL2
hsa04913__47	0.209120108408095	DOWN	-1.25656183498823	0.23100334138672	Ovarian steroidogenesis: INSR
hsa04913__51	0.209120108408095	DOWN	-1.25656183498823	0.23100334138672	Ovarian steroidogenesis: INSR*
hsa05215__46	0.21036985169375	UP	1.25312234091436	0.232247327457436	Prostate cancer: MTOR
hsa05223__22	0.211624990651396	DOWN	-1.24968284684049	0.23349580589194	Non-small cell lung cancer: BAD*
hsa04950__5	0.213728902023224	UP	1.24395035671737	0.235678759918802	Maturity onset diabetes of the young: GCK
hsa04015__95	0.214574678305114	DOWN	-1.24165736066812	0.236472622014844	Rap1 signaling pathway: THBS1
hsa04115__18	0.215422864924951	UP	1.23936436461887	0.237129211009949	p53 signaling pathway: CCNG1
hsa04115__16	0.215422864924951	DOWN	-1.23936436461887	0.237129211009949	p53 signaling pathway: PPM1D
hsa04014__24	0.217981910687019	DOWN	-1.23248537647112	0.239805626569618	Ras signaling pathway: PLD1
hsa04012__48	0.221427859703115	UP	1.22331339227413	0.243454036502137	ErbB signaling pathway: CAMK2A
hsa04910__39	0.224037817731127	UP	1.21643440412638	0.246179566968882	Insulin signaling pathway: BAD
hsa05231__50	0.226229525360934	UP	1.21070191400326	0.248442593894328	Choline metabolism in cancer: WASF2
hsa03320__63	0.227110478442261	UP	1.20840891795401	0.249264362729561	PPAR signaling pathway: DBI
hsa04550__9	0.235601683137989	DOWN	-1.18662545548615	0.258432902869983	Signaling pathways regulating pluripotency of stem cells: HNF1A
hsa04917__45	0.237417567364713	DOWN	-1.18203946338765	0.260272817431911	Prolactin signaling pathway: SLC2A2
hsa04668__48	0.239701297771044	UP	1.17630697326453	0.262623171143902	TNF signaling pathway: CASP3
hsa04662__6	0.242000472195419	DOWN	-1.17057448314141	0.26498769653566	B cell receptor signaling pathway: NFKB1
hsa04064__135	0.242462162874308	UP	1.16942798511679	0.265338616214807	NF-kappa B signaling pathway: CCL19
hsa05205__337	0.247581670485961	DOWN	-1.15681650684592	0.2707834451939	Proteoglycans in cancer: CTNNB1**
hsa04723__67	0.255641643501779	DOWN	-1.13732604042731	0.279436095485656	Retrograde endocannabinoid signaling: PRKACA
hsa04540__18 19	0.257564153533202	UP	1.13274004832881	0.281373863074934	Gap junction: GJA1 GJA1***
hsa04151__99	0.275320024651386	UP	1.09146611944233	0.300596354631002	PI3K-Akt signaling pathway: MYB
hsa05132__6	0.277850628483422	UP	1.08573362931921	0.303183119001365	Salmonella infection: NFKB1
hsa04115__23	0.279376569560045	UP	1.08229413524534	0.304671256066933	p53 signaling pathway: PTEN
hsa04931__77	0.283987999993275	UP	1.07197565302372	0.309520563797775	Insulin resistance: PPP2R4**
hsa04668__36	0.292314210910281	UP	1.05363168462973	0.318410668000243	TNF signaling pathway: CREB3
hsa04912__14	0.293366332397062	UP	1.05133868858048	0.31918664653971	GnRH signaling pathway: ATF4
hsa05200__219	0.293366332397062	UP	1.05133868858048	0.31918664653971	Pathways in cancer: MYC**
hsa04014__104	0.298665021295792	DOWN	-1.03987370833424	0.324763642948376	Ras signaling pathway: BRAP*
hsa05169__117	0.302949699806773	UP	1.03070172413725	0.329232207019622	Epstein-Barr virus infection: CDKN1A
hsa04015__14	0.305107290700478	DOWN	-1.02611573203875	0.331385317471791	Rap1 signaling pathway: MAPK14
hsa04742__37	0.307818267563719	DOWN	-1.02038324191563	0.334136640526995	Taste transduction: P2RY4
hsa04612__39	0.312189717155771	DOWN	-1.01121125771863	0.338686188531001	Antigen processing and presentation: PSME3
hsa05215__34	0.316047851436804	UP	1.00318577154626	0.342673925475912	Prostate cancer: BAD
hsa04390__59	0.321054109678699	DOWN	-0.992867289324644	0.347700675554049	Hippo signaling pathway: SERPINE1
hsa05020__62	0.321054109678699	UP	0.992867289324644	0.347700675554049	Prion diseases: NOTCH1
hsa05211__27	0.322734312161918	DOWN	-0.989427795250771	0.349318993405671	Renal cell carcinoma: VEGFA*
hsa04724__33 70 69	0.323857627379362	UP	0.987134799201522	0.350333035029258	Glutamatergic synapse: ITPR1 HOMER3 HOMER3
hsa05142__36	0.324983486615293	DOWN	-0.984841803152273	0.351348660155429	Chagas disease (American trypanosomiasis): SMAD2
hsa04728__24	0.329512359907581	DOWN	-0.975669818955279	0.356040094460233	Dopaminergic synapse: SLC6A3
hsa04380__48	0.330650936120395	DOWN	-0.97337682290603	0.3570650051553	Osteoclast differentiation: NFATC1
hsa04152__27	0.339271276721771	DOWN	-0.956179352536666	0.366163543343025	AMPK signaling pathway: ADIPOR1
hsa03320__44	0.342176475792333	DOWN	-0.950446862413544	0.369087025266242	PPAR signaling pathway: FABP1
hsa04010__86	0.34451205638065	DOWN	-0.945860870315047	0.371393088892278	MAPK signaling pathway: MAP4K2
hsa04917__33	0.350987206222391	DOWN	-0.93324939204418	0.378156514043505	Prolactin signaling pathway: CSN2
hsa04310__14	0.351579657191476	UP	0.932102894019556	0.378577751210764	Wnt signaling pathway: PRKCA
hsa04742__27	0.354551406037483	UP	0.926370403896434	0.381559044641713	Taste transduction: CALHM1
hsa04920__2	0.370259062137914	UP	0.896561455256202	0.398235133232479	Adipocytokine signaling pathway: C00638
hsa05216__11	0.374560804903155	UP	0.888535969083832	0.402401230653532	Thyroid cancer: MYC
hsa05222__19	0.374560804903155	DOWN	-0.888535969083832	0.402401230653532	Small cell lung cancer: CASP9
hsa05120__19	0.385763548637667	DOWN	-0.867899004640595	0.414199833080101	Epithelial cell signaling in Helicobacter pylori infection: CXCL1
hsa05169__104	0.38639186641868	UP	0.866752506615971	0.414637531125471	Epstein-Barr virus infection: IRF3
hsa04919__99	0.389542815277813	DOWN	-0.861020016492849	0.417780222549663	Thyroid hormone signaling pathway: WNT4
hsa05161__10	0.390174875563621	UP	0.859873518468225	0.418219390293237	Hepatitis B: CASP3
hsa04919__46	0.391440864928117	DOWN	-0.857580522418976	0.419337163739984	Thyroid hormone signaling pathway: ATP1B4
hsa04724__26	0.397808129503905	DOWN	-0.846115542172733	0.42591537056287	Glutamatergic synapse: PRKACA
hsa04015__67	0.403591705551703	UP	0.835797059951114	0.431861511806178	Rap1 signaling pathway: AKT3
hsa04910__18	0.404237418614462	DOWN	-0.83465056192649	0.432306266122126	Insulin signaling pathway: LIPE
hsa04340__26	0.408774692958954	DOWN	-0.82662507575412	0.436909924954423	Hedgehog signaling pathway: PTCH1**
hsa04024__3	0.413342146780728	DOWN	-0.81859958958175	0.441540587720857	cAMP signaling pathway: RYR2
hsa03320__57	0.421242004003396	DOWN	-0.804841613286258	0.449723707683171	PPAR signaling pathway: APOC3
hsa04540__1	0.423894756775147	DOWN	-0.800255621187761	0.452298834741909	Gap junction: C00681
hsa05222__35	0.425890879688024	DOWN	-0.796816127113888	0.454170807567422	Small cell lung cancer: NOS2
hsa05161__48	0.427224608611269	DOWN	-0.79452313106464	0.455334679285635	Hepatitis B: STAT1
hsa05152__9	0.428560767830422	DOWN	-0.792230135015391	0.456499820154968	Tuberculosis: TCIRG1
hsa04920__16	0.440015867584931	UP	0.772739668596778	0.468436155916195	Adipocytokine signaling pathway: POMC
hsa03320__46	0.460653327671649	UP	0.738344727858049	0.489851501242234	PPAR signaling pathway: APOA2
hsa05200__76	0.460653327671649	UP	0.738344727858049	0.489851501242234	Pathways in cancer: RAC1
hsa05132__20	0.461350439183764	UP	0.737198229833425	0.49031531404202	Salmonella infection: ACTB
hsa04917__46	0.46344530595643	DOWN	-0.733758735759552	0.492263272974636	Prolactin signaling pathway: GCK
hsa04024__43	0.464144770885618	UP	0.732612237734927	0.492727697454281	cAMP signaling pathway: MAPK8
hsa04024__76	0.470466331744058	UP	0.722293755513309	0.498874851776007	cAMP signaling pathway: C00416
hsa05142__67	0.470466331744058	DOWN	-0.722293755513309	0.498874851776007	Chagas disease (American trypanosomiasis): IFNGR1*
hsa05213__12	0.472584035255384	UP	0.718854261439436	0.500837790324234	Endometrial cancer: BAD
hsa04360__51	0.475415786294222	DOWN	-0.714268269340939	0.503554826632944	Axon guidance: FYN
hsa04918__14	0.476125175743444	UP	0.713121771316314	0.504022087448976	Thyroid hormone synthesis: DUOX2
hsa05020__48	0.477545693468096	UP	0.710828775267066	0.505241192582519	Prion diseases: SOD1
hsa04024__2	0.479680810189636	DOWN	-0.707389281193193	0.506644318350942	cAMP signaling pathway: CACNA1C
hsa04913__36	0.479680810189636	UP	0.707389281193193	0.506644318350942	Ovarian steroidogenesis: CYP19A1
hsa04913__37	0.479680810189636	UP	0.707389281193193	0.506644318350942	Ovarian steroidogenesis: CYP19A1*
hsa05152__15	0.481821123880599	UP	0.70394978711932	0.508619040321149	Tuberculosis: CTSD
hsa04950__7	0.488992871895782	UP	0.692484806873077	0.515899835088251	Maturity onset diabetes of the young: FOXA3
hsa04115__50	0.506437144882561	UP	0.664968854282094	0.534004149963149	p53 signaling pathway: RCHY1
hsa04210__99	0.507905463746587	UP	0.662675858232845	0.535252028255657	Apoptosis: BID**
hsa04931__46	0.51011212360527	UP	0.659236364158972	0.537276166061828	Insulin resistance: PIK3R5*
hsa04917__44	0.525698032962845	DOWN	-0.635159905641862	0.553381850945202	Prolactin signaling pathway: PRLR**
hsa05162__62	0.529444534563783	DOWN	-0.62942741551874	0.557013594874215	Measles: IL12A
hsa04014__79	0.533204566265087	UP	0.623694925395619	0.560655500846166	Ras signaling pathway: RAC1**
hsa04024__112	0.536222282842223	UP	0.619108933297122	0.563513237953321	cAMP signaling pathway: GLI1
hsa05152__129	0.543043427030327	DOWN	-0.608790451075503	0.570362548569024	Tuberculosis: IFNB1
hsa05217__4	0.544565084787203	UP	0.606497455026255	0.571641225874388	Basal cell carcinoma: PTCH1
hsa05212__19	0.549142731495319	UP	0.599618466878509	0.576124618916641	Pancreatic cancer: MAPK8
hsa04064__25	0.557584076671572	DOWN	-0.587006988607641	0.584654285751051	NF-kappa B signaling pathway: NFKB2
hsa04921__34 35	0.579351794488041	UP	0.554905043918161	0.607140001027903	Oxytocin signaling pathway: MYL9 ACTB
hsa04012__24	0.580921771205944	DOWN	-0.552612047868912	0.608445935393517	ErbB signaling pathway: CDKN1A
hsa04261__62	0.584067684594207	UP	0.548026055770415	0.611400099917836	Adrenergic signaling in cardiomyocytes: BCL2
hsa04810__48	0.58959203382532	DOWN	-0.540000569598045	0.616839327147982	Regulation of actin cytoskeleton: IQGAP2
hsa05212__31	0.59991493377994	UP	0.525096095277929	0.627290017013081	Pancreatic cancer: RAC1*
hsa04072__3	0.602308707631271	DOWN	-0.521656601204056	0.629442748408875	Phospholipase D signaling pathway: MAPK1
hsa04380__20	0.628105271469345	DOWN	-0.484968664416079	0.656036578705336	Osteoclast differentiation: MAP2K1
hsa05166__33	0.650669954486666	UP	0.444841233554228	0.679227135822469	HTLV-I infection: HLA-A
hsa04115__40	0.656020248016836	UP	0.445987731578853	0.684432007786582	p53 signaling pathway: PIDD1
hsa04152__82	0.665157890580403	DOWN	-0.433376253307985	0.693580286570798	AMPK signaling pathway: HMGCR
hsa05205__422	0.670163214334366	UP	0.426497265160239	0.698411913330157	Proteoglycans in cancer: CD63
hsa04919__27	0.672671395866009	DOWN	-0.423057771086367	0.70063722440811	Thyroid hormone signaling pathway: GATA4
hsa04620__23	0.676021307367332	DOWN	-0.418471778987869	0.703736308334192	Toll-like receptor signaling pathway: CD40
hsa04622__44	0.678537961361491	UP	0.415032284913996	0.705965021815195	RIG-I-like receptor signaling pathway: MAPK8
hsa04670__14	0.681058205474666	UP	0.411592790840124	0.708195001708299	Leukocyte transendothelial migration: SIPA1
hsa04360__81	0.683582014971206	UP	0.408153296766251	0.710426220205141	Axon guidance: FYN*
hsa05160__12 13 14	0.698798344849571	UP	0.387516332323013	0.725838634589466	Hepatitis C: IKBKG CHUK IKBKB
hsa05169__32	0.703897837394357	UP	0.380637344175268	0.730731511858562	Epstein-Barr virus infection: CR2
hsa05200__202	0.715848210082129	UP	0.364586371830527	0.74231721122755	Pathways in cancer: FIGF*
hsa05205__91	0.715848210082129	DOWN	-0.364586371830527	0.74231721122755	Proteoglycans in cancer: RAC1*
hsa04919__30	0.72270860704145	DOWN	-0.355414387633533	0.749017910993318	Thyroid hormone signaling pathway: MYH6
hsa04921__76	0.724427220414458	UP	0.353121391584284	0.750385196890168	Oxytocin signaling pathway: CDKN1A
hsa04810__8 79	0.746024576772588	DOWN	-0.324458940968677	0.771905385328025	Regulation of actin cytoskeleton: ARPC5 ACTB
hsa04810__8 82	0.746024576772588	DOWN	-0.324458940968677	0.771905385328025	Regulation of actin cytoskeleton: ARPC5 ACTB*
hsa05321__122	0.755592168719701	UP	0.311847462697809	0.781374620266549	Inflammatory bowel disease (IBD): IL4**
hsa04630__35	0.763448251563193	DOWN	-0.301528980476191	0.789064502028184	Jak-STAT signaling pathway: MTOR
hsa03320__26	0.765197392791233	DOWN	-0.299235984426942	0.790437548683193	PPAR signaling pathway: CPT2
hsa04510__23 4 5	0.776595643043959	UP	0.284331510106826	0.801770996307472	Focal adhesion: TLN1 ITGB1 ITGA11
hsa04550__62 63	0.78187280842872	DOWN	-0.27745252195908	0.806775951146383	Signaling pathways regulating pluripotency of stem cells: SMAD2 SMAD4
hsa04015__92	0.784515112775536	UP	0.274013027885208	0.809058121243267	Rap1 signaling pathway: C00076*
hsa04068__60	0.787160034500829	DOWN	-0.270573533811335	0.811340485368655	FoxO signaling pathway: RAG1
hsa05169__31	0.792457089776424	UP	0.263694545663589	0.816352451584375	Epstein-Barr virus infection: MYC
hsa04210__107	0.793340871609518	UP	0.262548047638965	0.816815067262622	Apoptosis: MCL1
hsa05218__9	0.818190570920204	UP	0.230446102949484	0.84193870906849	Melanoma: CCND1
hsa05142__29	0.822648085587556	DOWN	-0.224713612826363	0.846062262079375	Chagas disease (American trypanosomiasis): NOS2
hsa05152__13	0.826218230363158	DOWN	-0.220127620727866	0.849269176615085	Tuberculosis: LAMP1
hsa04722__84	0.842327352577377	UP	0.199490656284628	0.865354344173259	Neurotrophin signaling pathway: NFKB1*
hsa04920__26	0.846814150610599	DOWN	-0.193758166161507	0.869488409288151	Adipocytokine signaling pathway: NPY
hsa05223__9	0.849508624871376	DOWN	-0.190318672087634	0.871778648898589	Non-small cell lung cancer: BAD
hsa04668__111	0.864809633386648	UP	0.170828205669021	0.886996343413488	TNF signaling pathway: BAG4
hsa04620__18	0.867515251784391	UP	0.167388711595148	0.889285956411822	Toll-like receptor signaling pathway: CXCL11
hsa04917__40	0.873834346277418	DOWN	-0.159363225422778	0.895275210826209	Prolactin signaling pathway: TH
hsa04724__51	0.880161498704461	DOWN	-0.151337739250408	0.901266188591652	Glutamatergic synapse: ADRBK1
hsa05321__95	0.887401886605201	UP	0.142165755053413	0.908185264123732	Inflammatory bowel disease (IBD): SMAD2
hsa05161__125	0.890119489923061	UP	0.13872626097954	0.910470615985537	Hepatitis B: CDKN1A
hsa04950__18	0.893744964787214	DOWN	-0.134140268881043	0.913681604371695	Maturity onset diabetes of the young: SLC2A2
hsa04623__8	0.901002503780459	UP	0.124968284684049	0.92060016563539	Cytosolic DNA-sensing pathway: TBK1
hsa05145__13	0.904634417814973	UP	0.120382292585551	0.923808734279529	Toxoplasmosis: GNAI1
hsa04370__37	0.921911980402753	DOWN	-0.0985988301176898	0.940941125028122	VEGF signaling pathway: CASP9
hsa04913__40	0.927376110866556	UP	0.091719841969944	0.946004186926308	Ovarian steroidogenesis: HSD17B1
hsa05132__68	0.933755243132029	UP	0.0836943557975739	0.951994629324515	Salmonella infection: NOS2
hsa04914__23	0.936490483877767	UP	0.080254861723701	0.954265520176966	Progesterone-mediated oocyte maturation: PRKACA
hsa04932__56	0.940138632232411	UP	0.0756688696252038	0.956945010815114	Non-alcoholic fatty liver disease (NAFLD): CASP7
hsa04950__16	0.940138632232411	DOWN	-0.0756688696252038	0.956945010815114	Maturity onset diabetes of the young: PAX4
hsa04152__44	0.946525869605355	DOWN	-0.0676433834528337	0.962924801834576	AMPK signaling pathway: SLC2A4
hsa04662__29	0.950177289840278	UP	0.0630573913543365	0.965593903520758	B cell receptor signaling pathway: RAC1
hsa04950__22	0.950177289840278	UP	0.0630573913543365	0.965593903520758	Maturity onset diabetes of the young: NR5A2
hsa05160__70	0.952003397165738	UP	0.0607643953050879	0.966926693661849	Hepatitis C: CDKN1A
hsa04919__89	0.958396694915607	DOWN	-0.0527389091327178	0.972894321851121	Thyroid hormone signaling pathway: CASP9
hsa04010__62	0.970276753231164	DOWN	-0.0378344348126019	0.984422256653	MAPK signaling pathway: MEF2C
hsa04024__24	0.972105106254074	UP	0.0355414387633533	0.985745005208529	cAMP signaling pathway: PLN
hsa04152__77	0.973933605883655	DOWN	-0.0332484427141047	0.987066475434405	AMPK signaling pathway: CCND1
hsa05200__224	0.979419888372497	DOWN	-0.0263694545663589	0.991557096040906	Pathways in cancer: MYC***
hsa05221__12	0.979419888372497	DOWN	-0.0263694545663589	0.991557096040906	Acute myeloid leukemia: MYC
hsa04115__27	0.986736401378474	DOWN	-0.0171974703693645	0.998426331820222	p53 signaling pathway: THBS1
hsa05210__31	0.989480414445496	UP	0.0137579762954916	1	Colorectal cancer: BCL2
hsa04152__33	1	0	0	1	AMPK signaling pathway: CPT1C
hsa04152__41	1	0	0	1	AMPK signaling pathway: FBP1
hsa04211__2	1	0	0	1	Longevity regulating pathway - mammal: RPS6KB1
hsa04911__41	1	0	0	1	Insulin secretion: ABCC8
hsa04911__35	1	0	0	1	Insulin secretion: TRPM4
hsa04922__67	1	0	0	1	Glucagon signaling pathway: FBP1
hsa04922__60	1	0	0	1	Glucagon signaling pathway: CPT1C*
hsa04924__34	1	0	0	1	Renin secretion: REN
hsa04924__47	1	0	0	1	Renin secretion: KCNMA1
hsa04931__151	1	0	0	1	Insulin resistance: CPT1A
hsa04931__29	1	0	0	1	Insulin resistance: CPT1B
hsa04960__15	1	0	0	1	Aldosterone-regulated sodium reabsorption: C00762
hsa05030__13	1	0	0	1	Cocaine addiction: SLC6A3
hsa05031__15	1	0	0	1	Amphetamine addiction: MAOA
hsa05031__77	1	0	0	1	Amphetamine addiction: MAOA*
hsa05034__7	1	0	0	1	Alcoholism: GRIN3A
hsa05034__75	1	0	0	1	Alcoholism: SLC29A1
hsa05140__37	1	0	0	1	Leishmaniasis: ELK1
hsa05140__55	1	0	0	1	Leishmaniasis: JUN
hsa05140__41 57	1	0	0	1	Leishmaniasis: NOS2 CYBA
hsa05211__12	1	0	0	1	Renal cell carcinoma: EGLN2