p.value	UP.DOWN	statistic	FDRp.value	path.name
hsa04211__43 59 60 61	1.55914272090982e-31	UP	11.6833214455479	9.78476610046897e-29	Longevity regulating pathway - mammal: ULK3 RB1CC1 ATG13 ATG101
hsa04750__8	1.55914272090982e-31	DOWN	-11.6833214455479	9.78476610046897e-29	Inflammatory mediator regulation of TRP channels: ASIC2
hsa04530__11 24 23	1.56222981912756e-31	DOWN	-11.6833214455479	9.78476610046897e-29	Tight junction: TJP1 YBX3 CDK4
hsa04922__17	6.23993422092761e-27	DOWN	-10.7458457251608	2.93120910028074e-24	Glucagon signaling pathway: PKM
hsa05131__38	2.18526282802975e-26	UP	10.6295696668182	8.21221770773578e-24	Shigellosis: CXCL8
hsa04910__48	1.95420064281018e-24	DOWN	-10.202012910621	5.79578000077945e-22	Insulin signaling pathway: PPARGC1A
hsa04115__31	2.159151676714e-24	DOWN	-10.1923232390924	5.79578000077945e-22	p53 signaling pathway: ADGRB1
hsa04960__4	3.55015325844556e-24	DOWN	-10.1438748814497	8.18470360944543e-22	Aldosterone-regulated sodium reabsorption: ATP1B4
hsa04726__72	3.92029443773331e-24	DOWN	-10.1341852099212	8.18470360944543e-22	Serotonergic synapse: KCNJ3
hsa04920__40	7.18208635523312e-24	DOWN	-10.0748359718088	1.3495140261483e-21	Adipocytokine signaling pathway: PPARGC1A
hsa04211__42	2.6294030723077e-23	DOWN	-9.94644782405552	4.49149852078743e-21	Longevity regulating pathway - mammal: PPARGC1A
hsa04723__42	3.60593047783877e-23	DOWN	-9.91495639158773	5.21195643681465e-21	Retrograde endocannabinoid signaling: KCNJ3
hsa04723__50	3.60593047783877e-23	DOWN	-9.91495639158773	5.21195643681465e-21	Retrograde endocannabinoid signaling: KCNJ3*
hsa04922__50	5.18500352978093e-23	DOWN	-9.87862012335568	6.95901545175598e-21	Glucagon signaling pathway: PCK1
hsa04152__78	3.08842052590863e-22	UP	9.69814999113645	3.67026290030922e-20	AMPK signaling pathway: CCNA2
hsa04922__59	3.12529038876783e-22	DOWN	-9.69693878219538	3.67026290030922e-20	Glucagon signaling pathway: CPT1C
hsa04152__54	4.45877414286428e-22	DOWN	-9.66060251396332	4.9282568320247e-20	AMPK signaling pathway: SLC2A4*
hsa04152__68	1.16988013004912e-21	DOWN	-9.5612833807957	1.15694987598016e-19	AMPK signaling pathway: PPARGC1A**
hsa05032__37	1.16988013004912e-21	DOWN	-9.5612833807957	1.15694987598016e-19	Morphine addiction: KCNJ3
hsa04066__55	4.77054928918653e-21	DOWN	-9.4147270989264	4.48193105719075e-19	HIF-1 signaling pathway: ANGPT1
hsa05215__22	5.66827094576232e-21	DOWN	-9.39655896481037	5.07175290813686e-19	Prostate cancer: C16038
hsa04014__62	7.2177437623174e-21	DOWN	-9.37112357704792	6.16460933154291e-19	Ras signaling pathway: RASSF5
hsa04916__10	1.02944495028613e-20	DOWN	-9.3335760998748	8.41011765907671e-19	Melanogenesis: CAMK2A
hsa04724__66	1.24999472389099e-20	DOWN	-9.31298554787663	9.78641702579652e-19	Glutamatergic synapse: PLA2G4B
hsa04922__51	1.30833268882598e-20	DOWN	-9.30814071211235	9.83342848921605e-19	Glucagon signaling pathway: G6PC
hsa04728__61	1.36936152470189e-20	DOWN	-9.30329587634808	9.89627040351867e-19	Dopaminergic synapse: KCNJ3
hsa04530__1 5	1.66171034879674e-20	DOWN	-9.28270532434991	1.15642731310706e-18	Tight junction: IGSF5 IGSF5
hsa04114__80	2.83103790262487e-20	UP	9.22577850411969	1.89982864965434e-18	Oocyte meiosis: CDC25C*
hsa04915__28	3.79621559467433e-20	DOWN	-9.1942870716519	2.45968589737692e-18	Estrogen signaling pathway: KCNJ3
hsa04540__1	6.36363158330798e-20	DOWN	-9.13857146036275	3.98575458167857e-18	Gap junction: C00681
hsa04666__41	7.0381479136207e-20	UP	9.12767057989313	4.26602578377203e-18	Fc gamma R-mediated phagocytosis: MARCKS
hsa05166__5	7.78303688790597e-20	DOWN	-9.11676969942351	4.57010197261729e-18	HTLV-I infection: SLC2A1
hsa05120__20	9.62093856605967e-20	UP	9.09375672954321	5.4781041107958e-18	Epithelial cell signaling in Helicobacter pylori infection: CXCL8
hsa05166__64	1.099635388522e-19	UP	9.07922222225039	5.49791348024172e-18	HTLV-I infection: CCNB2
hsa05020__24	1.1118718054773e-19	DOWN	-9.07801101330932	5.49791348024172e-18	Prion diseases: PRNP*
hsa05020__26	1.1118718054773e-19	DOWN	-9.07801101330932	5.49791348024172e-18	Prion diseases: PRNP**
hsa05020__25 8	1.1118718054773e-19	DOWN	-9.07801101330932	5.49791348024172e-18	Prion diseases: PRNP PRNP*
hsa05020__10 34	1.1118718054773e-19	DOWN	-9.07801101330932	5.49791348024172e-18	Prion diseases: PRNP PRNP***
hsa04115__38	1.43561876163308e-19	UP	9.05015320766474	6.91673757207322e-18	p53 signaling pathway: GTSE1
hsa04390__88	1.53436979763802e-19	DOWN	-9.04288595401833	7.20770212440459e-18	Hippo signaling pathway: ID1
hsa04540__18 19	3.04187844651183e-19	DOWN	-8.96779099967207	1.37233765068136e-17	Gap junction: GJA1 GJA1***
hsa05200__146 147	3.21356341830653e-19	DOWN	-8.96173495496673	1.37233765068136e-17	Pathways in cancer: RARB RXRA
hsa05222__14 15	3.21356341830653e-19	DOWN	-8.96173495496673	1.37233765068136e-17	Small cell lung cancer: RXRA RARB
hsa05223__29 34	3.21356341830653e-19	DOWN	-8.96173495496673	1.37233765068136e-17	Non-small cell lung cancer: RARB RXRA
hsa05100__55	4.36865855771726e-19	DOWN	-8.92782110461681	1.82415765110016e-17	Bacterial invasion of epithelial cells: ACTB*
hsa04916__9	5.93194994737565e-19	DOWN	-8.89390725426689	2.42307259806932e-17	Melanogenesis: PRKACA
hsa04510__19 26	6.61491172946316e-19	DOWN	-8.8817951648562	2.64455726375772e-17	Focal adhesion: VCL ACTN4
hsa04971__52 53	6.98495690164039e-19	DOWN	-8.87573912015086	2.73431958712131e-17	Gastric acid secretion: EZR ACTB
hsa04066__88	7.61999131191975e-19	DOWN	-8.86604944862231	2.92203340308106e-17	HIF-1 signaling pathway: BCL2
hsa04910__18	8.7756339719504e-19	DOWN	-8.85030373238842	3.20564010572505e-17	Insulin signaling pathway: LIPE
hsa04971__49	8.7756339719504e-19	DOWN	-8.85030373238842	3.20564010572505e-17	Gastric acid secretion: KCNJ1
hsa05162__13	8.87138294293256e-19	UP	8.84909252344735	3.20564010572505e-17	Measles: IRF7
hsa04110__60 10 11 12 13 14 9	1.07823776496672e-18	DOWN	-8.82729076250811	3.792699406622e-17	Cell cycle: CDC6 ORC3 ORC5 ORC4 ORC2 ORC1 ORC6
hsa05200__189	1.08997215517609e-18	UP	8.82607955356704	3.792699406622e-17	Pathways in cancer: BIRC5
hsa04911__56	1.25449622516773e-18	DOWN	-8.81033383733315	4.18035664448042e-17	Insulin secretion: CAMK2A*
hsa04390__58	1.26812309066197e-18	DOWN	-8.80912262839208	4.18035664448042e-17	Hippo signaling pathway: SMAD7
hsa04390__79	1.26812309066197e-18	DOWN	-8.80912262839208	4.18035664448042e-17	Hippo signaling pathway: SNAI2
hsa04022__23	1.49096225153309e-18	UP	8.79095449427605	4.83020357005288e-17	cGMP-PKG signaling pathway: CACNA1C
hsa04923__66	1.59055644943661e-18	DOWN	-8.78368724062964	5.06551791269728e-17	Regulation of lipolysis in adipocytes: LIPE
hsa04010__134	1.80986418256509e-18	UP	8.76915273333682	5.66789133173299e-17	MAPK signaling pathway: ATF4*
hsa04360__145	1.90982222273082e-18	DOWN	-8.76309668863148	5.88287861723148e-17	Axon guidance: ABLIM3
hsa04015__63	2.14931891352553e-18	DOWN	-8.74977339027972	6.51382296534592e-17	Rap1 signaling pathway: GNAI1
hsa04510__19 23	2.29221261587135e-18	DOWN	-8.74250613663331	6.8366150876544e-17	Focal adhesion: VCL TLN1
hsa05020__49	2.44447882160809e-18	UP	8.7352388829869	7.17683704031499e-17	Prion diseases: BAX
hsa04724__67	2.66313311774643e-18	DOWN	-8.72554921145835	7.6985032742239e-17	Glutamatergic synapse: PLD1
hsa05210__21	2.90107658250149e-18	UP	8.7158595399298	8.25927711897016e-17	Colorectal cancer: BIRC5
hsa04540__14 16	3.95320619592022e-18	DOWN	-8.68073448063881	1.09236388854913e-16	Gap junction: GJA1 GJA1
hsa04540__14 15	3.95320619592022e-18	DOWN	-8.68073448063881	1.09236388854913e-16	Gap junction: GJA1 GJA1*
hsa04919__46	4.16933426245187e-18	DOWN	-8.67467843593347	1.13538827234015e-16	Thyroid hormone signaling pathway: ATP1B4
hsa05133__46	4.35060030233624e-18	DOWN	-8.66983360016919	1.16782542401283e-16	Pertussis: CFL1
hsa04360__33 134	5.73376440158486e-18	DOWN	-8.63834216770141	1.51742863529267e-16	Axon guidance: NCK1 PAK4
hsa05020__62	5.85658679829799e-18	DOWN	-8.63591974981927	1.52840647138916e-16	Prion diseases: NOTCH1
hsa04022__39	6.37438627541524e-18	DOWN	-8.62623007829072	1.6407495632199e-16	cGMP-PKG signaling pathway: KCNJ8
hsa04630__31	6.64997746353281e-18	UP	8.62138524252645	1.68855508837543e-16	Jak-STAT signaling pathway: BCL2L1
hsa04270__28	7.71040490429875e-18	DOWN	-8.60442831735149	1.90629615989176e-16	Vascular smooth muscle contraction: KCNMB2
hsa04916__6	7.71040490429875e-18	DOWN	-8.60442831735149	1.90629615989176e-16	Melanogenesis: DCT
hsa04014__58 59	9.723068617421e-18	DOWN	-8.57778172064798	2.37268128988754e-16	Ras signaling pathway: STK4 STK4
hsa04919__45	1.05768307371179e-17	DOWN	-8.56809204911943	2.5479314044929e-16	Thyroid hormone signaling pathway: SLC9A1
hsa04110__43 83 84 85	1.11475707259515e-17	DOWN	-8.56203600441408	2.65142853089404e-16	Cell cycle: SMC1B SMC3 STAG1 RAD21
hsa04723__9	1.26443150643786e-17	DOWN	-8.54750149712126	2.89267403331804e-16	Retrograde endocannabinoid signaling: PRKCA
hsa04725__20	1.26443150643786e-17	DOWN	-8.54750149712126	2.89267403331804e-16	Cholinergic synapse: PRKCA
hsa04726__18	1.26443150643786e-17	DOWN	-8.54750149712126	2.89267403331804e-16	Serotonergic synapse: PRKCA
hsa04071__11	1.27776447453644e-17	DOWN	-8.54629028818019	2.89267403331804e-16	Sphingolipid signaling pathway: PRKCA
hsa05205__120	1.57553742507369e-17	DOWN	-8.52206610935882	3.51948297953096e-16	Proteoglycans in cancer: PLAU
hsa04630__1	1.59210246546105e-17	UP	8.52085490041775	3.51948297953096e-16	Jak-STAT signaling pathway: MYC
hsa04540__16 17	1.6775405828643e-17	DOWN	-8.51479885571241	3.66523111070002e-16	Gap junction: GJA1 GJA1**
hsa04540__14 31	1.92143057791149e-17	DOWN	-8.49905313947852	4.14984834011e-16	Gap junction: GJA1 TJP1
hsa05200__217	2.17744539663976e-17	UP	8.48451863218569	4.64934079577966e-16	Pathways in cancer: E2F1*
hsa03320__65	2.54520714470185e-17	DOWN	-8.46635049806966	5.36933824837354e-16	PPAR signaling pathway: ME1
hsa04610__11	2.57179586138168e-17	UP	8.4651392891286	5.36933824837354e-16	Complement and coagulation cascades: F2R
hsa04520__44 49	2.85322156802702e-17	DOWN	-8.45302719971791	5.89143222672831e-16	Adherens junction: ACTB VCL
hsa04390__89	3.26490228850438e-17	DOWN	-8.43728148348402	6.66820804358667e-16	Hippo signaling pathway: ID2
hsa04014__26	3.47416430995781e-17	DOWN	-8.4300142298376	7.01930617033412e-16	Ras signaling pathway: PRKCA
hsa04020__64	3.81309967142796e-17	DOWN	-8.41911334936799	7.54190977117173e-16	Calcium signaling pathway: C01330*
hsa04020__12	3.81309967142796e-17	DOWN	-8.41911334936799	7.54190977117173e-16	Calcium signaling pathway: C01330
hsa04360__40 139	3.9331704999095e-17	DOWN	-8.41547972254478	7.69836184305204e-16	Axon guidance: UNC5D DCC
hsa04970__45	5.58394779128896e-17	DOWN	-8.37429861854845	1.08167401029195e-15	Salivary secretion: KCNMA1
hsa04151__4	7.67514426550729e-17	UP	8.33675114137532	1.47159143621308e-15	PI3K-Akt signaling pathway: RPS6
hsa04725__64	7.83390099227028e-17	DOWN	-8.33432872349318	1.48685858227029e-15	Cholinergic synapse: KCNJ3
hsa04340__52	8.32985772971526e-17	DOWN	-8.32706146984677	1.5651802674135e-15	Hedgehog signaling pathway: BCL2*
hsa05110__50	8.58927349585952e-17	DOWN	-8.32342784302357	1.59794503947723e-15	Vibrio cholerae infection: ACTB
hsa05012__70	1.0642638209129e-16	DOWN	-8.29799245526113	1.96054090146602e-15	Parkinson's disease: PRKACA
hsa04914__39	1.15462088667209e-16	DOWN	-8.28830278373258	2.10634237481248e-15	Progesterone-mediated oocyte maturation: PIK3R5
hsa04728__44	1.23986030594048e-16	DOWN	-8.2798243211451	2.24009376429054e-15	Dopaminergic synapse: FOS
hsa04970__28	1.358578142981e-16	DOWN	-8.26892344067548	2.41019858586333e-15	Salivary secretion: AQP5
hsa04310__14	1.37249201004458e-16	DOWN	-8.26771223173441	2.41019858586333e-15	Wnt signaling pathway: PRKCA
hsa04360__108	1.37249201004458e-16	DOWN	-8.26771223173441	2.41019858586333e-15	Axon guidance: CFL1
hsa04722__50	1.40065022751907e-16	UP	8.26528981385227	2.43687201621142e-15	Neurotrophin signaling pathway: RHOA
hsa04961__12	1.42937786788927e-16	DOWN	-8.26286739597013	2.46403762730637e-15	Endocrine and other factor-regulated calcium reabsorption: SLC8A1
hsa03460__25 40	1.50376318108601e-16	UP	8.25681135126479	2.54555947500956e-15	Fanconi anemia pathway: MLH1 PMS2
hsa04972__51	1.50376318108601e-16	DOWN	-8.25681135126479	2.54555947500956e-15	Pancreatic secretion: CLCA1
hsa05205__415	1.69821661183627e-16	DOWN	-8.24227684397197	2.84906161932174e-15	Proteoglycans in cancer: MAPK1******
hsa04022__48	2.49252333109391e-16	DOWN	-8.19625090421136	4.14464720276589e-15	cGMP-PKG signaling pathway: SLC8A2
hsa04014__45	2.56895714303228e-16	DOWN	-8.19261727738816	4.23427234364707e-15	Ras signaling pathway: RAB5A
hsa04066__63	2.64770033663335e-16	DOWN	-8.18898365056495	4.28881804528799e-15	HIF-1 signaling pathway: TIMP1*
hsa04066__57	2.64770033663335e-16	DOWN	-8.18898365056495	4.28881804528799e-15	HIF-1 signaling pathway: TIMP1
hsa04810__21 82	2.81239169961949e-16	DOWN	-8.18171639691854	4.51665299451711e-15	Regulation of actin cytoskeleton: CFL1 ACTB
hsa05034__99	3.10959502947501e-16	DOWN	-8.16960430750785	4.95163479693521e-15	Alcoholism: PDYN
hsa04724__68	3.14096560071956e-16	DOWN	-8.16839309856678	4.95955828886727e-15	Glutamatergic synapse: MAPK1
hsa04931__87	3.57830626804055e-16	DOWN	-8.15264738233289	5.60303123137349e-15	Insulin resistance: C00031*
hsa04726__45	3.76191440554353e-16	DOWN	-8.14659133762755	5.84184889918702e-15	Serotonergic synapse: TRPC1
hsa04914__34	3.79989315869947e-16	DOWN	-8.14538012868648	5.8524583977019e-15	Progesterone-mediated oocyte maturation: MAPK14
hsa04916__8	3.95507512925798e-16	DOWN	-8.1405352929222	6.04193997388272e-15	Melanogenesis: TYR*
hsa04530__20 22	4.11649921539202e-16	DOWN	-8.13569045715793	6.23782421429162e-15	Tight junction: ACTB MYL12B
hsa04520__18	4.59465363768108e-16	DOWN	-8.12236715880618	6.90668334816221e-15	Adherens junction: SNAI2
hsa04068__72	4.68729013692814e-16	DOWN	-8.11994474092404	6.99001441848251e-15	FoxO signaling pathway: SMAD2
hsa04151__103	5.38933131964989e-16	DOWN	-8.10298781574908	7.9736642123009e-15	PI3K-Akt signaling pathway: BCL2*
hsa04022__49	5.6643823403801e-16	DOWN	-8.09693177104373	8.31513626372985e-15	cGMP-PKG signaling pathway: ATP1B4
hsa05169__45	6.25663470200617e-16	DOWN	-8.08481968163305	9.1133462054803e-15	Epstein-Barr virus infection: RB1
hsa05010__61	6.3191136760084e-16	UP	8.08360847269198	9.13354969016906e-15	Alzheimer's disease: GAPDH
hsa05012__71	7.18950188396477e-16	DOWN	-8.06786275645809	1.03122702595189e-14	Parkinson's disease: PRKACA*
hsa04722__70	7.40656164642044e-16	UP	8.06422912963488	1.05431282830485e-14	Neurotrophin signaling pathway: ZNF274
hsa04014__76	7.48033990131245e-16	DOWN	-8.06301792069381	1.05680892289971e-14	Ras signaling pathway: RALBP1*
hsa04723__73	7.93846043094886e-16	DOWN	-8.0557506670474	1.10491608516688e-14	Retrograde endocannabinoid signaling: MAPK14*
hsa04723__68	7.93846043094886e-16	DOWN	-8.0557506670474	1.10491608516688e-14	Retrograde endocannabinoid signaling: MAPK14
hsa05214__35	8.17777732600351e-16	UP	8.05211704022419	1.1298561467324e-14	Glioma: E2F1
hsa04015__30	8.67793344962333e-16	DOWN	-8.04484978657778	1.18158238781465e-14	Rap1 signaling pathway: ITGAL
hsa04066__47	8.67793344962333e-16	DOWN	-8.04484978657778	1.18158238781465e-14	HIF-1 signaling pathway: PGK1
hsa05205__270	9.02799083830419e-16	DOWN	-8.04000495081351	1.22040250253047e-14	Proteoglycans in cancer: MAPK1****
hsa04152__30	9.57931509984528e-16	UP	8.0327376971671	1.28568093375781e-14	AMPK signaling pathway: ACACA
hsa04270__48	9.77035966110229e-16	DOWN	-8.03031527928496	1.30202168817101e-14	Vascular smooth muscle contraction: KCNMB2*
hsa05161__66 67	1.15532960817525e-15	DOWN	-8.00972472728679	1.52877769983189e-14	Hepatitis B: NFKB1 NFKBIA
hsa04360__89	1.16676214617571e-15	DOWN	-8.00851351834572	1.53310914172318e-14	Axon guidance: CAMK2A
hsa04960__3	1.2256177641929e-15	DOWN	-8.00245747364038	1.59926095758227e-14	Aldosterone-regulated sodium reabsorption: SCNN1A
hsa05321__95	1.53626922813155e-15	DOWN	-7.9745996679958	1.99079302045461e-14	Inflammatory bowel disease (IBD): SMAD2
hsa04110__59 15 16 17 18 19 20	1.62932307646801e-15	UP	7.96733241434939	2.09691647992012e-14	Cell cycle: CDC45 MCM7 MCM6 MCM5 MCM4 MCM3 MCM2
hsa05220__19 41	1.64536273504011e-15	DOWN	-7.96612120540832	2.10315413546963e-14	Chronic myeloid leukemia: SMAD4 SMAD3
hsa05212__34	1.72792337700312e-15	UP	7.96006516070298	2.1937621793168e-14	Pancreatic cancer: E2F1
hsa05200__121 122	1.7620783456676e-15	DOWN	-7.95764274282084	2.20729680767295e-14	Pathways in cancer: SMAD2 SMAD4
hsa05212__38 39	1.7620783456676e-15	DOWN	-7.95764274282084	2.20729680767295e-14	Pancreatic cancer: SMAD2 SMAD4
hsa04014__69	1.79689804607831e-15	DOWN	-7.95522032493871	2.23600756859679e-14	Ras signaling pathway: PLCE1*
hsa04910__17	1.94308236343045e-15	DOWN	-7.94553065341016	2.40200773742488e-14	Insulin signaling pathway: C00031
hsa05166__65	1.96215971990221e-15	UP	7.94431944446909	2.40973732921324e-14	HTLV-I infection: PTTG2
hsa04520__1 13	2.04033115983353e-15	DOWN	-7.93947460870481	2.48946899306961e-14	Adherens junction: SMAD4 SMAD2
hsa04919__88	2.0603484201404e-15	DOWN	-7.93826339976374	2.49767398802826e-14	Thyroid hormone signaling pathway: FOXO1
hsa04550__69	2.08055905769947e-15	DOWN	-7.93705219082268	2.50600671116494e-14	Signaling pathways regulating pluripotency of stem cells: ID1
hsa05200__5	2.12156783451349e-15	DOWN	-7.93462977294054	2.52305440572839e-14	Pathways in cancer: CASP3*
hsa05210__7	2.12156783451349e-15	DOWN	-7.93462977294054	2.52305440572839e-14	Colorectal cancer: CASP3*
hsa05231__38	2.31617718068234e-15	UP	7.92372889247092	2.73716787578749e-14	Choline metabolism in cancer: RPS6KB1
hsa05161__125	2.33885675207252e-15	DOWN	-7.92251768352985	2.74669489821516e-14	Hepatitis B: CDKN1A
hsa04921__46	2.36175498333448e-15	DOWN	-7.92130647458878	2.75635876626428e-14	Oxytocin signaling pathway: C00942*
hsa05205__150	2.47959931700519e-15	DOWN	-7.91525042988344	2.87602908435355e-14	Proteoglycans in cancer: PRKCA
hsa05200__168	2.52834177483306e-15	UP	7.9128280120013	2.91457312571246e-14	Pathways in cancer: E2F1
hsa04915__66	2.8969791765685e-15	DOWN	-7.89587108682634	3.31916089803184e-14	Estrogen signaling pathway: AKT3*
hsa05215__25	3.07072121578619e-15	DOWN	-7.88860383317993	3.49690009967409e-14	Prostate cancer: FOXO1
hsa04610__58	3.4162991343552e-15	UP	7.87528053482818	3.8438479481757e-14	Complement and coagulation cascades: F2RL2
hsa04728__74	3.4162991343552e-15	DOWN	-7.87528053482818	3.8438479481757e-14	Dopaminergic synapse: GRIN2A
hsa04015__82	3.44955143251307e-15	DOWN	-7.87406932588711	3.85815901291194e-14	Rap1 signaling pathway: ITGA2B
hsa04010__131	3.55123211429125e-15	UP	7.8704356990639	3.94838174127412e-14	MAPK signaling pathway: MYC
hsa05130__26	3.58577704147406e-15	DOWN	-7.86922449012283	3.96333827113515e-14	Pathogenic Escherichia coli infection: CTNNB1
hsa04520__69	3.69140915076338e-15	DOWN	-7.86559086329963	4.05623262823649e-14	Adherens junction: IQGAP1**
hsa04916__4	3.87431089134753e-15	DOWN	-7.85953481859428	4.23245939816396e-14	Melanogenesis: TYR
hsa04390__77	3.9883044666339e-15	DOWN	-7.85590119177108	4.33180583399139e-14	Hippo signaling pathway: CCND1
hsa04370__16	4.26728802294505e-15	DOWN	-7.8474227291836	4.60818057190445e-14	VEGF signaling pathway: HSPB1
hsa04015__100 101 48	4.30868012618823e-15	DOWN	-7.84621152024253	4.62629140406153e-14	Rap1 signaling pathway: PRKCI PARD6A PARD3
hsa04015__96	4.47823792807574e-15	DOWN	-7.84136668447826	4.7810278788945e-14	Rap1 signaling pathway: PLCE1
hsa04022__50	5.27518262010196e-15	DOWN	-7.82077613248009	5.600038498967e-14	cGMP-PKG signaling pathway: ATP2B1
hsa04024__108	5.32618181813076e-15	UP	7.81956492353902	5.62241327880208e-14	cAMP signaling pathway: AMH
hsa05205__233 234	5.53507699951053e-15	DOWN	-7.81472008777475	5.81028473859234e-14	Proteoglycans in cancer: ITGA2 C00925
hsa04014__64	5.86362729377149e-15	DOWN	-7.80745283412833	6.12097538055369e-14	Ras signaling pathway: PIK3R5*
hsa04550__34	6.03502718651052e-15	DOWN	-7.80381920730513	6.26509175881396e-14	Signaling pathways regulating pluripotency of stem cells: MAPK1*
hsa05120__52	7.52356401707987e-15	DOWN	-7.77596140166055	7.76745977367751e-14	Epithelial cell signaling in Helicobacter pylori infection: LYN
hsa05205__318	8.04446799125247e-15	DOWN	-7.76748293907307	8.25986631451552e-14	Proteoglycans in cancer: HSPB2
hsa04728__54	8.19970926652347e-15	DOWN	-7.76506052119093	8.37350745206391e-14	Dopaminergic synapse: CAMK2A
hsa04066__46	8.2784318113397e-15	DOWN	-7.76384931224986	8.40820182351746e-14	HIF-1 signaling pathway: ENO1
hsa04931__13	9.37208157604235e-15	DOWN	-7.74810359601597	9.46781789321698e-14	Insulin resistance: AKT2
hsa05034__61	9.923655352586e-15	DOWN	-7.74083634236956	9.97141626070006e-14	Alcoholism: CRH
hsa04713__60	1.01145179861141e-14	DOWN	-7.73841392448742	1.01091379233555e-13	Circadian entrainment: PER1
hsa04360__40 142	1.09147594071259e-14	DOWN	-7.72872425295887	1.08512343523755e-13	Axon guidance: UNC5D PTPN11
hsa04022__37 38	1.14462146658992e-14	DOWN	-7.72266820825353	1.13197038722235e-13	cGMP-PKG signaling pathway: ATP2A1 PLN
hsa04114__56	1.31980855420245e-14	DOWN	-7.7045000741375	1.29838757766828e-13	Oocyte meiosis: REC8
hsa05200__227	1.38387199932634e-14	DOWN	-7.69844402943216	1.3543205660074e-13	Pathways in cancer: FOXO1
hsa04390__96	1.64086181059817e-14	DOWN	-7.67664226849292	1.59750224979998e-13	Hippo signaling pathway: FGF1
hsa04918__14	1.76964042140321e-14	DOWN	-7.66695259696437	1.71399708856528e-13	Thyroid hormone synthesis: DUOX2
hsa03320__43	1.83770791863929e-14	DOWN	-7.6621077612001	1.77079650211447e-13	PPAR signaling pathway: ILK
hsa04919__49	2.13663182774182e-14	DOWN	-7.642728418143	2.04833224710555e-13	Thyroid hormone signaling pathway: ACTB
hsa04630__24	2.21862160084626e-14	UP	7.63788358237873	2.11613704974118e-13	Jak-STAT signaling pathway: MCL1
hsa04931__137	2.34734184400696e-14	UP	7.63061632873231	2.22760369943892e-13	Insulin resistance: MLXIP*
hsa04931__61	2.36949790716734e-14	DOWN	-7.62940511979125	2.23732993345097e-13	Insulin resistance: ACACB
hsa04066__48	2.53045542109749e-14	DOWN	-7.62092665720377	2.3773628681211e-13	HIF-1 signaling pathway: PFKFB3
hsa05133__60	2.65196188114292e-14	UP	7.61487061249842	2.47912257446147e-13	Pertussis: C5
hsa04115__43 57	2.85840922704295e-14	UP	7.60518094096987	2.64578863921857e-13	p53 signaling pathway: CDK1 CCNB3
hsa04725__50	2.85840922704295e-14	DOWN	-7.60518094096987	2.64578863921857e-13	Cholinergic synapse: BCL2
hsa05205__45 46	2.93983516675626e-14	DOWN	-7.60154731414667	2.69460989187074e-13	Proteoglycans in cancer: PAK1 FLNA
hsa05321__74	2.93983516675626e-14	DOWN	-7.60154731414667	2.69460989187074e-13	Inflammatory bowel disease (IBD): IL5
hsa04071__65	3.05196092376064e-14	UP	7.59670247838239	2.78380319210982e-13	Sphingolipid signaling pathway: BAX*
hsa04066__11	3.13880528650203e-14	DOWN	-7.59306885155919	2.84918605475232e-13	HIF-1 signaling pathway: SLC2A1
hsa04151__5	3.16828997704533e-14	UP	7.59185764261812	2.86212349368662e-13	PI3K-Akt signaling pathway: EIF4B
hsa04960__27	3.22807887925953e-14	DOWN	-7.58943522473598	2.90218192063572e-13	Aldosterone-regulated sodium reabsorption: KCNJ1
hsa04340__13	3.51115147376583e-14	DOWN	-7.57853434426636	3.14164458057429e-13	Hedgehog signaling pathway: GLI1*
hsa04931__124	3.57729689273227e-14	DOWN	-7.57611192638423	3.17063248181317e-13	Insulin resistance: FOXO1*
hsa05164__36	3.57729689273227e-14	DOWN	-7.57611192638423	3.17063248181317e-13	Influenza A: IL33
hsa04360__123	3.81860030162527e-14	DOWN	-7.56763346379675	3.36861500786567e-13	Axon guidance: ENAH
hsa04620__23	4.2700344738509e-14	DOWN	-7.55309895650392	3.74924989549806e-13	Toll-like receptor signaling pathway: CD40
hsa04340__20 22	4.30994013047997e-14	DOWN	-7.55188774756285	3.76668721170784e-13	Hedgehog signaling pathway: GLI1 SUFU*
hsa04014__66	4.39085472851591e-14	DOWN	-7.54946532968072	3.81963705318583e-13	Ras signaling pathway: RAF1*
hsa04270__65	5.23787892466743e-14	DOWN	-7.52645235980041	4.51471874433196e-13	Vascular smooth muscle contraction: NPR2
hsa04540__22	5.23793872413181e-14	UP	7.52645235980041	4.51471874433196e-13	Gap junction: C00547
hsa04914__11	5.69344840556292e-14	UP	7.5155514793308	4.88492673701038e-13	Progesterone-mediated oocyte maturation: CDK1
hsa04015__67	6.01850344192941e-14	DOWN	-7.50828422568438	5.14034907608426e-13	Rap1 signaling pathway: AKT3
hsa04310__16	6.1308572780366e-14	DOWN	-7.50586180780225	5.1891355069508e-13	Wnt signaling pathway: CAMK2A
hsa05100__24	6.1308572780366e-14	DOWN	-7.50586180780225	5.1891355069508e-13	Bacterial invasion of epithelial cells: ACTB
hsa05205__422	6.36178620009237e-14	DOWN	-7.50101697203797	5.36044675783568e-13	Proteoglycans in cancer: CD63
hsa04976__34	6.48043621539181e-14	UP	7.49859455415583	5.43604448603625e-13	Bile secretion: SLCO1B1
hsa03320__38	6.60126099159101e-14	DOWN	-7.4961721362737	5.51278640142201e-13	PPAR signaling pathway: SORBS1
hsa04620__21	6.66250111931476e-14	UP	7.49496092733263	5.53930955893471e-13	Toll-like receptor signaling pathway: IFNA1
hsa04921__34 35	7.23940060892334e-14	DOWN	-7.48406004686301	5.99243777276077e-13	Oxytocin signaling pathway: MYL9 ACTB
hsa04722__46	7.3741204885546e-14	DOWN	-7.48163762898087	6.0771808763132e-13	Neurotrophin signaling pathway: ATF4*
hsa04931__149	7.51130404181504e-14	DOWN	-7.47921521109874	6.16320536880806e-13	Insulin resistance: ACACB*
hsa05223__14	7.8653337056903e-14	DOWN	-7.47315916639339	6.42563566651829e-13	Non-small cell lung cancer: CCND1
hsa04071__59 60	8.31186811352868e-14	DOWN	-7.46589191274698	6.73189663160361e-13	Sphingolipid signaling pathway: TP53 BCL2
hsa04950__31	8.31186811352868e-14	UP	7.46589191274698	6.73189663160361e-13	Maturity onset diabetes of the young: NKX6-1*
hsa04630__27	8.7832970387955e-14	UP	7.45862465910057	7.08318246175826e-13	Jak-STAT signaling pathway: PIM1
hsa05132__6	8.94620540017944e-14	DOWN	-7.45620224121843	7.18372647305007e-13	Salmonella infection: NFKB1
hsa04064__3	9.80635781310422e-14	DOWN	-7.44409015180775	7.84091333226503e-13	NF-kappa B signaling pathway: BCL2
hsa05215__13	9.89671755009334e-14	DOWN	-7.44287894286668	7.87963232060397e-13	Prostate cancer: BCL2
hsa04340__50	1.11485623739843e-13	DOWN	-7.42713322663279	8.76491577435837e-13	Hedgehog signaling pathway: BCL2
hsa04340__31	1.11485623739843e-13	DOWN	-7.42713322663279	8.76491577435837e-13	Hedgehog signaling pathway: GLI1***
hsa05130__28	1.11485623739843e-13	DOWN	-7.42713322663279	8.76491577435837e-13	Pathogenic Escherichia coli infection: ROCK1
hsa04014__103	1.156415153604e-13	DOWN	-7.42228839086851	9.05376697342464e-13	Ras signaling pathway: KSR2
hsa05161__100	1.19949558439066e-13	UP	7.41744355510424	9.35208383016619e-13	Hepatitis B: MMP9*
hsa05205__284	1.22162337334939e-13	DOWN	-7.4150211372221	9.48524925009714e-13	Proteoglycans in cancer: PRKCA*
hsa04014__27	1.27871296113286e-13	DOWN	-7.40896509251676	9.88766112744298e-13	Ras signaling pathway: ABL1
hsa04920__16	1.32626520241035e-13	DOWN	-7.40412025675248	1.02133291611846e-12	Adipocytokine signaling pathway: POMC
hsa04340__51	1.35068870871554e-13	DOWN	-7.40169783887035	1.03589554435776e-12	Hedgehog signaling pathway: CCND1*
hsa05164__78	1.37555404138557e-13	UP	7.39927542098821	1.05067725356239e-12	Influenza A: GSK3B
hsa04530__7 52	1.42664169907223e-13	DOWN	-7.39443058522393	1.08528734921325e-12	Tight junction: PARD6A MPP5
hsa04919__32	1.47959258128336e-13	DOWN	-7.38958574945966	1.12103002428687e-12	Thyroid hormone signaling pathway: PLN
hsa04620__20	1.49312919230159e-13	UP	7.38837454051859	1.12674287242357e-12	Toll-like receptor signaling pathway: IFNB1*
hsa04360__11	1.53447335372196e-13	DOWN	-7.38474091369538	1.15331017265743e-12	Axon guidance: NFATC2
hsa04115__11 12	1.59135301959448e-13	UP	7.37989607793111	1.19129574654105e-12	p53 signaling pathway: CDK2 CCNE1
hsa04071__69	1.72701471457437e-13	DOWN	-7.36899519746149	1.287722479637e-12	Sphingolipid signaling pathway: RAC1
hsa04916__15	1.79089712631297e-13	DOWN	-7.36415036169722	1.33007735191386e-12	Melanogenesis: MITF*
hsa04728__70 73	1.80722707249038e-13	DOWN	-7.36293915275615	1.33692112961001e-12	Dopaminergic synapse: KIF5A GRIA1
hsa04713__14	1.90832382468381e-13	DOWN	-7.35567189910974	1.4061727319925e-12	Circadian entrainment: PRKCA
hsa04066__45	1.96093541057924e-13	DOWN	-7.35203827228653	1.43929595174937e-12	HIF-1 signaling pathway: ALDOA
hsa04919__30	1.99679877340345e-13	DOWN	-7.34961585440439	1.459916301644e-12	Thyroid hormone signaling pathway: MYH6
hsa04910__42	2.20587082350868e-13	DOWN	-7.33629255605264	1.6065237509197e-12	Insulin signaling pathway: PCK1
hsa04066__44	2.24612954732966e-13	DOWN	-7.3338701381705	1.62326054593555e-12	HIF-1 signaling pathway: GAPDH
hsa04152__64	2.24612954732966e-13	DOWN	-7.3338701381705	1.62326054593555e-12	AMPK signaling pathway: ACACB
hsa04724__36	2.9441165566509e-13	DOWN	-7.29753386993844	2.11953831798737e-12	Glutamatergic synapse: TRPC1
hsa04810__48	3.19228116017279e-13	DOWN	-7.28663298946883	2.28942606868881e-12	Regulation of actin cytoskeleton: IQGAP2
hsa04014__44	3.65229033958874e-13	DOWN	-7.2684648553528	2.60937397265675e-12	Ras signaling pathway: ETS1
hsa05200__65	3.71834659978272e-13	DOWN	-7.26604243747066	2.64650502310293e-12	Pathways in cancer: STK4
hsa05211__21	4.36815783569043e-13	DOWN	-7.24424067653143	3.09727115972163e-12	Renal cell carcinoma: TGFB1*
hsa04064__93	4.44690497071021e-13	DOWN	-7.24181825864929	3.14125354885883e-12	NF-kappa B signaling pathway: PLAU
hsa04919__40	4.52704561388268e-13	DOWN	-7.23939584076715	3.18588715673616e-12	Thyroid hormone signaling pathway: RCAN2
hsa04066__89	5.03853642882101e-13	DOWN	-7.22486133347433	3.53261565289354e-12	HIF-1 signaling pathway: CDKN1A
hsa05223__24	6.81608708828757e-13	DOWN	-7.18368022947799	4.76112551631686e-12	Non-small cell lung cancer: STK4
hsa04015__17	6.87676054516493e-13	DOWN	-7.18246902053693	4.78571594976478e-12	Rap1 signaling pathway: ACTB
hsa04713__61	7.44722841381875e-13	DOWN	-7.17156814006731	5.14461109910494e-12	Circadian entrainment: FOS
hsa05217__5	7.44722841381875e-13	DOWN	-7.17156814006731	5.14461109910494e-12	Basal cell carcinoma: BMP2
hsa03320__60	8.06407841090955e-13	DOWN	-7.16066725959769	5.55033089161137e-12	PPAR signaling pathway: CYP27A1
hsa04010__13	8.73100240080612e-13	UP	7.14976637912807	5.987428288728e-12	MAPK signaling pathway: STMN1
hsa03460__7	9.87744388068371e-13	UP	7.13280945395311	6.72453516369735e-12	Fanconi anemia pathway: FANCI
hsa05200__66	9.87744388068371e-13	DOWN	-7.13280945395311	6.72453516369735e-12	Pathways in cancer: CCND1
hsa05031__98	1.117126523479e-12	DOWN	-7.11585252877815	7.57790880006153e-12	Amphetamine addiction: FOS
hsa05020__48	1.16725220975672e-12	DOWN	-7.10979648407281	7.88944928824773e-12	Prion diseases: SOD1
hsa04915__21	1.23032220729773e-12	DOWN	-7.1025292304264	8.28593343194422e-12	Estrogen signaling pathway: CREB3
hsa04010__117	1.2742142359874e-12	UP	7.09768439466212	8.55088767650119e-12	MAPK signaling pathway: JUND
hsa04012__29	1.33124460346764e-12	DOWN	-7.09162834995678	8.90180999969996e-12	ErbB signaling pathway: STAT5A*
hsa04750__62	1.57090302136335e-12	UP	6.83121842762703	1.04671162309991e-11	Inflammatory mediator regulation of TRP channels: TRPM8*
hsa04722__53	1.62752342556356e-12	DOWN	-7.0637705443122	1.08060654298019e-11	Neurotrophin signaling pathway: JUN
hsa04014__30	1.7756902980761e-12	DOWN	-7.05165845490151	1.17070949827543e-11	Ras signaling pathway: C01245
hsa04015__18	1.7756902980761e-12	DOWN	-7.05165845490151	1.17070949827543e-11	Rap1 signaling pathway: CDH1
hsa04390__94	1.87085950670715e-12	DOWN	-7.0443912012551	1.22914161297298e-11	Hippo signaling pathway: GLI2
hsa03320__56	2.00557117205316e-12	DOWN	-7.03470152972655	1.31305513320136e-11	PPAR signaling pathway: FADS2
hsa04310__22	2.02306518430668e-12	DOWN	-7.03349032078548	1.31990954212231e-11	Wnt signaling pathway: ROCK2
hsa04152__57	2.05850342976788e-12	UP	7.03106790290335	1.33838337181102e-11	AMPK signaling pathway: ACACA*
hsa04621__34 35	2.14978458371177e-12	DOWN	-7.025011858198	1.39291214923946e-11	NOD-like receptor signaling pathway: CASP1 PYCARD
hsa04014__24	2.40610437606922e-12	DOWN	-7.00926614196411	1.55363234454779e-11	Ras signaling pathway: PLD1
hsa05030__77	2.57849467385189e-12	DOWN	-6.99957647043556	1.65924366170127e-11	Cocaine addiction: BDNF
hsa04390__18	2.64621626171397e-12	UP	6.99594284361236	1.69701036032783e-11	Hippo signaling pathway: MOB1A
hsa04915__3 11	2.81108944814441e-12	DOWN	-6.98746438102488	1.77846366096409e-11	Estrogen signaling pathway: ESR1 C00951
hsa04915__12 14	2.81108944814441e-12	DOWN	-6.98746438102488	1.77846366096409e-11	Estrogen signaling pathway: ESR1 FOS
hsa04915__12 13	2.81108944814441e-12	DOWN	-6.98746438102488	1.77846366096409e-11	Estrogen signaling pathway: ESR1 C00951*
hsa05200__219	2.81108944814441e-12	UP	6.98746438102488	1.77846366096409e-11	Pathways in cancer: MYC**
hsa04919__21 53	2.93498187507609e-12	DOWN	-6.98140833631953	1.85061441049261e-11	Thyroid hormone signaling pathway: THRA C02465
hsa04722__37	3.19904267942679e-12	UP	6.96929624690885	2.00366706488098e-11	Neurotrophin signaling pathway: NFKB1
hsa05164__90	3.19904267942679e-12	DOWN	-6.96929624690885	2.00366706488098e-11	Influenza A: MAPK1
hsa04012__47	3.57738376943911e-12	DOWN	-6.95355053067496	2.22579606052188e-11	ErbB signaling pathway: PRKCA
hsa04971__56	3.57738376943911e-12	DOWN	-6.95355053067496	2.22579606052188e-11	Gastric acid secretion: CAMK2A
hsa04611__43	3.89795039498045e-12	DOWN	-6.94143844126427	2.41724382579811e-11	Platelet activation: MYL12B
hsa04610__45	4.1389353710254e-12	UP	6.93295997867679	2.55824327702524e-11	Complement and coagulation cascades: C4A
hsa04066__51	4.21043088044828e-12	DOWN	-6.93053756079465	2.59390151618436e-11	HIF-1 signaling pathway: TFRC
hsa04621__23	4.24663126629705e-12	DOWN	-6.92932635185358	2.60765364358567e-11	NOD-like receptor signaling pathway: CASP1
hsa04713__56	4.70556645823895e-12	DOWN	-6.91479184456076	2.88005191369087e-11	Circadian entrainment: KCNJ3
hsa04064__129	5.43994972414033e-12	DOWN	-6.89420129256259	3.31872257521418e-11	NF-kappa B signaling pathway: PTGS2
hsa04210__74	5.53340896325387e-12	UP	6.89177887468046	3.3648140588848e-11	Apoptosis: BAX*
hsa04914__30	6.07615650556425e-12	UP	6.8784555763287	3.6829348625662e-11	Progesterone-mediated oocyte maturation: CDK1*
hsa04530__11 13	6.28633018870252e-12	DOWN	-6.87361074056443	3.7980753776759e-11	Tight junction: TJP1 EPB41
hsa04211__50	6.39401745479946e-12	DOWN	-6.87118832268229	3.8507560248616e-11	Longevity regulating pathway - mammal: PPARGC1A*
hsa04921__77	6.61484350993676e-12	DOWN	-6.86634348691801	3.97101947449558e-11	Oxytocin signaling pathway: KCNJ3
hsa04022__46	7.07914951135882e-12	DOWN	-6.85665381538947	4.23621717574625e-11	cGMP-PKG signaling pathway: VASP
hsa05205__77	7.20003215215011e-12	DOWN	-6.85423139750733	4.28134188109822e-11	Proteoglycans in cancer: MIR21
hsa05211__2	7.20012791073463e-12	DOWN	-6.85423139750733	4.28134188109822e-11	Renal cell carcinoma: TGFB1
hsa04152__81	7.44819375076087e-12	DOWN	-6.84938656174305	4.41487572797466e-11	AMPK signaling pathway: LIPE
hsa04360__125	8.24371986767862e-12	DOWN	-6.83485205445023	4.87105334319752e-11	Axon guidance: ENAH*
hsa04068__60	8.89443488147081e-12	DOWN	-6.82395117398061	5.23907308535537e-11	FoxO signaling pathway: RAG1
hsa04970__32	9.3559306424231e-12	DOWN	-6.8166839203342	5.49368552409781e-11	Salivary secretion: RYR3
hsa04810__82 83	9.51491410658799e-12	UP	6.81426150245206	5.56963352220525e-11	Regulation of actin cytoskeleton: ACTB ARPC5
hsa04919__101	1.21404065266004e-11	DOWN	-6.77913644316107	7.08441734890748e-11	Thyroid hormone signaling pathway: NOTCH1
hsa04611__92	1.27662441205546e-11	DOWN	-6.77186918951466	7.42655501626072e-11	Platelet activation: RHOA*
hsa05217__22	1.29817961473203e-11	DOWN	-6.76944677163253	7.50547537255844e-11	Basal cell carcinoma: LEF1
hsa05218__8	1.29817961473203e-11	UP	6.76944677163253	7.50547537255844e-11	Melanoma: CDK4
hsa04360__122	1.3423648403563e-11	DOWN	-6.76460193586825	7.73712740806594e-11	Axon guidance: CFL1**
hsa04115__24	1.57318224310224e-11	DOWN	-6.74158896598795	9.03978420424803e-11	p53 signaling pathway: SERPINB5
hsa04024__113	1.59962963012632e-11	DOWN	-6.73916654810581	9.16373193599804e-11	cAMP signaling pathway: PTCH1
hsa04390__75	1.61301611081267e-11	DOWN	-6.73795533916474	9.21233213439822e-11	Hippo signaling pathway: NKD1
hsa05161__48	1.65383718554944e-11	DOWN	-6.73432171234153	9.41684870196181e-11	Hepatitis B: STAT1
hsa04012__48	1.79734856371567e-11	DOWN	-6.72220962293085	1.02030753813346e-10	ErbB signaling pathway: CAMK2A
hsa04920__3	1.98571688379511e-11	DOWN	-6.70767511563803	1.12046907647177e-10	Adipocytokine signaling pathway: C15493
hsa05160__15 16	1.98571688379511e-11	DOWN	-6.70767511563803	1.12046907647177e-10	Hepatitis C: TRAF6 RIPK1
hsa05010__47	2.0357504076711e-11	DOWN	-6.70404148881482	1.14526198084252e-10	Alzheimer's disease: C00533
hsa04740__13	2.10438592982034e-11	UP	6.69919665305054	1.18034064541266e-10	Olfactory transduction: CNGA3
hsa04010__66	2.13954818463985e-11	UP	6.69677423516841	1.19294096110928e-10	MAPK signaling pathway: TP53
hsa04722__84	2.13954818463985e-11	DOWN	-6.69677423516841	1.19294096110928e-10	Neurotrophin signaling pathway: NFKB1*
hsa04510__24 69	2.22998965418201e-11	DOWN	-6.69071819046306	1.23968951485444e-10	Focal adhesion: ZYX ACTB
hsa04931__135	2.50360589212202e-11	UP	6.6737612652881	1.38769187943872e-10	Insulin resistance: SREBF1**
hsa04962__10	3.00125976337941e-11	DOWN	-6.64711466858459	1.65863738099703e-10	Vasopressin-regulated water reabsorption: AQP2
hsa04071__24	3.39480681730737e-11	DOWN	-6.62894653446857	1.87062815534327e-10	Sphingolipid signaling pathway: PTEN
hsa04360__114	3.47936912378347e-11	DOWN	-6.62531290764536	1.90604506810179e-10	Axon guidance: RAF1
hsa04550__36	3.47936912378347e-11	DOWN	-6.62531290764536	1.90604506810179e-10	Signaling pathways regulating pluripotency of stem cells: AKT3*
hsa04933__21	3.83871685051961e-11	DOWN	-6.61077840035254	2.09678748899022e-10	AGE-RAGE signaling pathway in diabetic complications: SMAD4
hsa04666__38	3.99894291493656e-11	DOWN	-6.60472235564719	2.17797499627994e-10	Fc gamma R-mediated phagocytosis: CFL1
hsa05142__36	4.03176450485194e-11	DOWN	-6.60351114670612	2.18950448110312e-10	Chagas disease (American trypanosomiasis): SMAD2
hsa04390__17 51	4.16570704591154e-11	DOWN	-6.59866631094185	2.25572436290138e-10	Hippo signaling pathway: YWHAQ YAP1
hsa05321__81	4.3748216323066e-11	DOWN	-6.59139905729544	2.36215225491497e-10	Inflammatory bowel disease (IBD): IL13
hsa04950__22	4.41065854027823e-11	UP	6.59018784835437	2.37467833730166e-10	Maturity onset diabetes of the young: NR5A2
hsa04611__34	4.55690045328205e-11	DOWN	-6.58534301259009	2.44640455763342e-10	Platelet activation: C02198*
hsa05210__9 11	5.02467454267457e-11	DOWN	-6.57080850529727	2.68984714122094e-10	Colorectal cancer: SMAD2 SMAD4
hsa05030__69	5.49453382978966e-11	DOWN	-6.55748520694552	2.93301962107238e-10	Cocaine addiction: PRKACA**
hsa04010__118	5.9106996347865e-11	UP	6.5465843264759	3.13734593609148e-10	MAPK signaling pathway: JUN
hsa05020__52	5.9106996347865e-11	DOWN	-6.5465843264759	3.13734593609148e-10	Prion diseases: FYN
hsa04750__53	6.20511024862146e-11	UP	6.53931707282949	3.28433863581964e-10	Inflammatory mediator regulation of TRP channels: TRPM8
hsa04970__12	7.00356621634879e-11	UP	6.52114893871346	3.68711192365429e-10	Salivary secretion: BEST2
hsa04510__47	7.00531642759224e-11	DOWN	-6.52114893871346	3.68711192365429e-10	Focal adhesion: CCND1
hsa04115__52 53	7.29383574213286e-11	UP	6.51509289400811	3.828245072477e-10	p53 signaling pathway: CDK4 CCND1
hsa04972__39	7.53298887430854e-11	DOWN	-6.51024805824384	3.94275378685954e-10	Pancreatic secretion: KCNMA1*
hsa04022__71	7.71736934734268e-11	UP	6.50661443142063	4.02803805657136e-10	cGMP-PKG signaling pathway: PPIF
hsa04010__67	8.36440913627623e-11	UP	6.49450234200995	4.35366337037757e-10	MAPK signaling pathway: ELK1
hsa05166__60	8.56865974424806e-11	UP	6.49086871518674	4.44765515454202e-10	HTLV-I infection: POLD3
hsa03460__48	8.84859540051122e-11	UP	6.48602387942247	4.58030599381834e-10	Fanconi anemia pathway: RAD51
hsa05110__52	9.21111283234283e-11	DOWN	-6.47996783471713	4.75485742087148e-10	Vibrio cholerae infection: ADCY3
hsa04510__44	9.74313622533952e-11	DOWN	-6.47148937212964	5.01571314175698e-10	Focal adhesion: BCL2
hsa04014__54	1.01414280624968e-10	DOWN	-6.4654333274243	5.20648724847857e-10	Ras signaling pathway: RHOA
hsa04390__78	1.08988438918401e-10	DOWN	-6.45453244695468	5.58008928413284e-10	Hippo signaling pathway: SOX2
hsa04380__68	1.16183281309348e-10	DOWN	-6.44484277542613	5.93229308642022e-10	Osteoclast differentiation: TGFBR1
hsa04115__39	1.18053319367136e-10	UP	6.442420357544	6.01144138457583e-10	p53 signaling pathway: BAX
hsa04919__102	1.2091366163867e-10	DOWN	-6.43878673072079	6.1404532491638e-10	Thyroid hormone signaling pathway: BMP4
hsa04973__5	1.41790265562977e-10	DOWN	-6.41456255189942	7.18123743915996e-10	Carbohydrate digestion and absorption: SLC2A5
hsa04024__93	1.58459304233318e-10	UP	6.39760562672446	8.00389872726893e-10	cAMP signaling pathway: ORAI1
hsa03320__32	1.62272789620275e-10	DOWN	-6.39397199990125	8.17454615808301e-10	PPAR signaling pathway: FABP3
hsa04530__11 36 14	1.70170699521131e-10	DOWN	-6.38670474625484	8.54948514439053e-10	Tight junction: TJP1 CTNNB1 CTNNA1
hsa04270__10 3 71	1.71523033595726e-10	DOWN	-6.38549353731377	8.5944474700365e-10	Vascular smooth muscle contraction: ACTA2 MYL9 MYH11
hsa04015__14	1.85637115665706e-10	DOWN	-6.37338144790309	9.27691862595378e-10	Rap1 signaling pathway: MAPK14
hsa04610__52	2.02474069621248e-10	UP	6.36005814955133	1.00914794912022e-09	Complement and coagulation cascades: CPB2
hsa04066__43	2.12277403995469e-10	DOWN	-6.35279089590492	1.05520963520499e-09	HIF-1 signaling pathway: PFKL
hsa04750__60	2.15624141281656e-10	DOWN	-6.35036847802278	1.06901784028557e-09	Inflammatory mediator regulation of TRP channels: TRPV3
hsa04024__2	2.19068973136444e-10	UP	6.34794606014064	1.08323842242994e-09	cAMP signaling pathway: CACNA1C
hsa04151__105 62	2.48421723546478e-10	UP	6.32856671708355	1.22515595418328e-09	PI3K-Akt signaling pathway: CCND1 CDK2
hsa04340__32	2.66585701635279e-10	DOWN	-6.31766583661393	1.31129458998086e-09	Hedgehog signaling pathway: PTCH1***
hsa05200__194	2.70794914732003e-10	DOWN	-6.31524341873179	1.32852126574787e-09	Pathways in cancer: BCL2
hsa04925__5	2.79408961499038e-10	DOWN	-6.31039858296752	1.36366087962777e-09	Aldosterone synthesis and secretion: KCNK3
hsa05205__400	2.79408961499038e-10	DOWN	-6.31039858296752	1.36366087962777e-09	Proteoglycans in cancer: ITGA2*
hsa04024__92	2.86044537316994e-10	UP	6.30676495614431	1.39242923735397e-09	cAMP signaling pathway: GRIN3A
hsa04540__21	2.95131821112074e-10	DOWN	-6.30192012038004	1.43295269216948e-09	Gap junction: C03758
hsa04071__66	3.14159999888603e-10	DOWN	-6.29223044885149	1.52140886543991e-09	Sphingolipid signaling pathway: C01245
hsa04066__58	3.19101150534816e-10	DOWN	-6.28980803096935	1.54136519757048e-09	HIF-1 signaling pathway: EDN1
hsa05205__17	3.55877855361827e-10	DOWN	-6.27285110579439	1.71460125698685e-09	Proteoglycans in cancer: AKT3
hsa04930__3	3.58657609030099e-10	DOWN	-6.27163989685332	1.72357454569707e-09	Type II diabetes mellitus: SLC2A4
hsa04010__65	3.75786757883253e-10	UP	6.26437264320691	1.80128397464957e-09	MAPK signaling pathway: ELK4
hsa04970__27	4.22179283602221e-10	DOWN	-6.24620450909088	2.01851112948746e-09	Salivary secretion: PRKCA
hsa05205__146	5.88363693030029e-10	DOWN	-6.19412252462493	2.80592735838433e-09	Proteoglycans in cancer: PTK2
hsa04971__37	5.97478723681552e-10	DOWN	-6.19170010674279	2.84218359948769e-09	Gastric acid secretion: KCNQ1
hsa04210__102	6.25658341422138e-10	DOWN	-6.18443285309638	2.96871723114191e-09	Apoptosis: PIDD1
hsa04020__16	6.55133215811233e-10	UP	6.17716559944997	3.10074386022495e-09	Calcium signaling pathway: C06124
hsa04623__25	7.348733754756e-10	DOWN	-6.15899746533394	3.46941475507199e-09	Cytosolic DNA-sensing pathway: NFKB1*
hsa04920__6	7.40513634196345e-10	DOWN	-6.15778625639287	3.48728099913517e-09	Adipocytokine signaling pathway: PTPN11
hsa05216__15	7.46196113123011e-10	DOWN	-6.1565750474518	3.50525624139535e-09	Thyroid cancer: CCND1
hsa04151__73	7.51921119896575e-10	DOWN	-6.15536383851073	3.5233411079443e-09	PI3K-Akt signaling pathway: MAPK1
hsa04068__52	7.57688964335159e-10	DOWN	-6.15415262956967	3.53274829773142e-09	FoxO signaling pathway: CAT
hsa04730__20	7.57688964335159e-10	DOWN	-6.15415262956967	3.53274829773142e-09	Long-term depression: C00025
hsa04610__46	7.99289818889975e-10	UP	6.14567416698219	3.71748903389669e-09	Complement and coagulation cascades: C2
hsa04151__96	8.11579476264572e-10	DOWN	-6.14325174910005	3.76532798987934e-09	PI3K-Akt signaling pathway: BCL2
hsa04022__44	8.17793227121434e-10	DOWN	-6.14204054015898	3.77551222054342e-09	cGMP-PKG signaling pathway: BAD
hsa05161__97	8.17793227121434e-10	DOWN	-6.14204054015898	3.77551222054342e-09	Hepatitis B: BCL2
hsa04630__28	8.30360247059119e-10	UP	6.13961812227684	3.82413456917668e-09	Jak-STAT signaling pathway: CCND1
hsa05205__431	8.49564665358506e-10	DOWN	-6.13598449545364	3.90301224011891e-09	Proteoglycans in cancer: CDKN1A*
hsa04950__15	8.82538809148434e-10	UP	6.12992845074829	4.04461078631685e-09	Maturity onset diabetes of the young: IAPP
hsa04972__23	9.09813771101088e-10	DOWN	-6.12508361498402	4.15946490486361e-09	Pancreatic secretion: KCNMA1
hsa05200__204	9.45065414095174e-10	DOWN	-6.11902757027867	4.31014056573988e-09	Pathways in cancer: TGFB1*
hsa04114__59	9.59535968202891e-10	UP	6.11660515239654	4.36554015557683e-09	Oocyte meiosis: REC8*
hsa04723__40	9.81647748656897e-10	DOWN	-6.11297152557333	4.43393298011132e-09	Retrograde endocannabinoid signaling: GRIA1
hsa04724__4	9.81647748656897e-10	DOWN	-6.11297152557333	4.43393298011132e-09	Glutamatergic synapse: GRIA1
hsa05031__12	9.81647748656897e-10	DOWN	-6.11297152557333	4.43393298011132e-09	Amphetamine addiction: GRIA1
hsa04066__5	1.01960961390682e-09	DOWN	-6.10691548086799	4.59435603005017e-09	HIF-1 signaling pathway: VEGFA
hsa04921__67	1.05900158760702e-09	DOWN	-6.10085943616265	4.74907871864819e-09	Oxytocin signaling pathway: RYR1
hsa05031__55	1.05900158760702e-09	DOWN	-6.10085943616265	4.74907871864819e-09	Amphetamine addiction: GRIA1*
hsa04020__22	1.09156514085232e-09	DOWN	-6.09601460039837	4.8834545230036e-09	Calcium signaling pathway: C00575
hsa04024__77	1.21348241439598e-09	DOWN	-6.07905767522341	5.40315984988161e-09	cAMP signaling pathway: RHOA*
hsa04630__33	1.21348241439598e-09	DOWN	-6.07905767522341	5.40315984988161e-09	Jak-STAT signaling pathway: RAF1
hsa04152__61	1.22268042142219e-09	UP	6.07784646628234	5.43124470887067e-09	AMPK signaling pathway: RPS6KB1
hsa04920__2	1.41092750385129e-09	DOWN	-6.05483349640204	6.25267165032213e-09	Adipocytokine signaling pathway: C00638
hsa04213__55	1.42158138496155e-09	DOWN	-6.05362228746097	6.28506217021822e-09	Longevity regulating pathway - multiple species: CRYAB
hsa05205__369	1.44312489500157e-09	DOWN	-6.05119986957883	6.36533257677922e-09	Proteoglycans in cancer: HOXD10
hsa04913__36	1.46498649501071e-09	DOWN	-6.0487774516967	6.43156454234843e-09	Ovarian steroidogenesis: CYP19A1
hsa04913__37	1.46498649501071e-09	DOWN	-6.0487774516967	6.43156454234843e-09	Ovarian steroidogenesis: CYP19A1*
hsa04910__43	1.6151618178487e-09	DOWN	-6.0330317354628	7.07433346325804e-09	Insulin signaling pathway: G6PC
hsa04064__50	1.62731591346442e-09	DOWN	-6.03182052652173	7.11099209627823e-09	NF-kappa B signaling pathway: NFKBIA*
hsa05200__211	1.6894358350723e-09	UP	6.02576448181639	7.36531307215974e-09	Pathways in cancer: CXCL8
hsa04211__38	1.70213421675227e-09	UP	6.02455327287532	7.40349581777204e-09	Longevity regulating pathway - mammal: BAX
hsa04971__55	1.78030061883989e-09	DOWN	-6.01728601922891	7.72560014503501e-09	Gastric acid secretion: MYLK4
hsa05205__91	1.82068459352728e-09	UP	6.01365239240571	7.88264136229899e-09	Proteoglycans in cancer: RAC1*
hsa04725__61	1.91841616345589e-09	DOWN	-6.00517392981823	8.28667579570946e-09	Cholinergic synapse: FOS
hsa05142__44	2.03637443619429e-09	DOWN	-5.99548425828968	8.7760265266263e-09	Chagas disease (American trypanosomiasis): PLCB1
hsa05231__60	2.21016920339026e-09	DOWN	-5.98216095993792	9.50322181503501e-09	Choline metabolism in cancer: PRKCA
hsa04520__4	2.2600226864151e-09	UP	5.97852733311472	9.69539412733782e-09	Adherens junction: CTNND1
hsa04022__51	2.29386509885538e-09	DOWN	-5.97610491523258	9.81816063951995e-09	cGMP-PKG signaling pathway: GTF2I
hsa05205__236	2.45236402205932e-09	DOWN	-5.96520403476296	1.04727090851124e-08	Proteoglycans in cancer: ITGAV
hsa04012__8	2.47061995956368e-09	DOWN	-5.96399282582189	1.04792210023028e-08	ErbB signaling pathway: STAT5A
hsa05200__129 130	2.47061995956368e-09	DOWN	-5.96399282582189	1.04792210023028e-08	Pathways in cancer: CTBP1 HDAC1
hsa05220__12 13	2.47061995956368e-09	DOWN	-5.96399282582189	1.04792210023028e-08	Chronic myeloid leukemia: HDAC1 CTBP1
hsa05161__69	2.48900823536581e-09	DOWN	-5.96278161688082	1.05334380050729e-08	Hepatitis B: SMAD4
hsa04921__41	2.60216964296521e-09	DOWN	-5.95551436323441	1.09875882227677e-08	Oxytocin signaling pathway: PTGS2
hsa04520__58	2.63091950615893e-09	UP	5.31841846023232	1.10840756772929e-08	Adherens junction: CDH1*
hsa04390__14	2.72033569162277e-09	DOWN	-5.948247109588	1.14351471242935e-08	Hippo signaling pathway: AREG
hsa04152__56	2.74053155033031e-09	UP	5.94703590064693	1.14943276407827e-08	AMPK signaling pathway: FASN
hsa04360__82	3.1300410786315e-09	DOWN	-5.9252341397077	1.30987687900859e-08	Axon guidance: ILK
hsa04350__21	3.17651134030833e-09	DOWN	-5.92281172182556	1.32636995743097e-08	TGF-beta signaling pathway: CDKN2B
hsa04725__53	3.7340488837743e-09	DOWN	-5.89616512512205	1.5557157101135e-08	Cholinergic synapse: CHRNA7
hsa04390__60	3.78931747666392e-09	DOWN	-5.89374270723991	1.57524945545387e-08	Hippo signaling pathway: CTGF*
hsa05205__256	4.0476009213339e-09	DOWN	-5.88284182677029	1.67890554772327e-08	Proteoglycans in cancer: ACTB
hsa03320__40	4.07733536701801e-09	DOWN	-5.88163061782923	1.68751391071076e-08	PPAR signaling pathway: FABP4
hsa04151__110	4.1374434107523e-09	DOWN	-5.87920819994709	1.70862772940738e-08	PI3K-Akt signaling pathway: BCL2**
hsa04971__39	4.19841354226011e-09	DOWN	-5.87678578206495	1.73000417673394e-08	Gastric acid secretion: EZR
hsa04390__12	4.32298823597901e-09	DOWN	-5.87194094630068	1.77355783742458e-08	Hippo signaling pathway: CTGF
hsa04742__49	4.32298823597901e-09	DOWN	-5.87194094630068	1.77355783742458e-08	Taste transduction: HTR1A
hsa05211__43	4.85825173931504e-09	DOWN	-5.85256160324358	1.98881372944945e-08	Renal cell carcinoma: RAP1A
hsa04064__131	5.37908659718119e-09	DOWN	-5.83560467806862	2.19723993828336e-08	NF-kappa B signaling pathway: CCL4L1
hsa04921__76	6.08486495142336e-09	DOWN	-5.81501412607045	2.48014343681659e-08	Oxytocin signaling pathway: CDKN1A
hsa05217__4	6.2635864382461e-09	DOWN	-5.81016929030618	2.54746296914814e-08	Basal cell carcinoma: PTCH1
hsa04062__42	6.73302050112781e-09	DOWN	-5.79805720089549	2.73247203490694e-08	Chemokine signaling pathway: PAK1
hsa04922__78	6.78180359109139e-09	UP	5.79684599195442	2.74633813527171e-08	Glucagon signaling pathway: ACACA
hsa05212__54	6.98039636202548e-09	DOWN	-5.79200115619015	2.82068059446148e-08	Pancreatic cancer: C00416
hsa05200__223	7.13304101109749e-09	DOWN	-5.78836752936694	2.87001799996835e-08	Pathways in cancer: CCND1****
hsa05221__17	7.13304101109749e-09	DOWN	-5.78836752936694	2.87001799996835e-08	Acute myeloid leukemia: CCND1
hsa04151__99	7.66566479663514e-09	UP	5.77625543995626	3.07773165659774e-08	PI3K-Akt signaling pathway: MYB
hsa05215__43	8.00349699485982e-09	DOWN	-5.76898818630984	3.20651830561655e-08	Prostate cancer: C05981
hsa05205__34	8.47677541567136e-09	DOWN	-5.7592985147813	3.38890659703117e-08	Proteoglycans in cancer: SLC9A1
hsa05014__31 34	8.72345598747506e-09	DOWN	-5.75445367901702	3.4801218260012e-08	Amyotrophic lateral sclerosis (ALS): NEFL PRPH
hsa04390__74	8.91303229004928e-09	DOWN	-5.75082005219381	3.54821772733106e-08	Hippo signaling pathway: AXIN1
hsa05200__192	9.78184679301458e-09	DOWN	-5.73507433595992	3.88585414885294e-08	Pathways in cancer: PTGS2
hsa03320__61	9.8519874238629e-09	DOWN	-5.73386312701885	3.90546083743426e-08	PPAR signaling pathway: APOA1
hsa04064__51	1.01374707071382e-08	DOWN	-5.72901829125458	4.01016999130792e-08	NF-kappa B signaling pathway: TNFAIP3
hsa04911__25	1.06565298790084e-08	DOWN	-5.7205398286671	4.20664278207076e-08	Insulin secretion: PRKCA
hsa05216__5	1.08868084684453e-08	UP	5.71690620184389	4.28853524364962e-08	Thyroid cancer: MAPK1
hsa03320__44	1.14430907257464e-08	DOWN	-5.70842773925641	4.49823587315429e-08	PPAR signaling pathway: FABP1
hsa04064__116	1.15247810151382e-08	DOWN	-5.70721653031534	4.51147156821763e-08	NF-kappa B signaling pathway: GADD45B
hsa05200__200	1.15247810151382e-08	DOWN	-5.70721653031534	4.51147156821763e-08	Pathways in cancer: FIGF
hsa04370__23	1.1607037895276e-08	DOWN	-5.70600532137428	4.52481829983893e-08	VEGF signaling pathway: PTK2
hsa05205__121	1.1607037895276e-08	DOWN	-5.70600532137428	4.52481829983893e-08	Proteoglycans in cancer: PLAUR
hsa04710__7	1.20269553154492e-08	DOWN	-5.69994927666893	4.67880932458159e-08	Circadian rhythm: PER1
hsa05161__68	1.28203045666426e-08	DOWN	-5.68904839619931	4.9771389009755e-08	Hepatitis B: JUN
hsa04064__115	1.36644054042166e-08	DOWN	-5.6781475157297	5.2939005679429e-08	NF-kappa B signaling pathway: XIAP
hsa05020__46	1.37614618246268e-08	DOWN	-5.67693630678863	5.32053225688761e-08	Prion diseases: PRKACA
hsa04024__60	1.4256877614809e-08	UP	5.67088026208329	5.47825624503602e-08	cAMP signaling pathway: PDE3A
hsa04062__60	1.4256877614809e-08	UP	5.67088026208329	5.47825624503602e-08	Chemokine signaling pathway: GSK3A
hsa04066__42	1.4256877614809e-08	DOWN	-5.67088026208329	5.47825624503602e-08	HIF-1 signaling pathway: HK1
hsa05166__62 63	1.4459857740537e-08	UP	5.66845784420115	5.54491279478958e-08	HTLV-I infection: ANAPC10 CDC20
hsa04010__14	1.60742948955751e-08	UP	5.65028971008512	6.15144605066917e-08	MAPK signaling pathway: MAPT
hsa04530__30	1.67679520895093e-08	UP	5.64302245643871	6.40385812524147e-08	Tight junction: AKT3
hsa05152__120	1.70055661192477e-08	DOWN	-5.64060003855657	6.48143179271123e-08	Tuberculosis: TGFB1
hsa04930__9	1.73679493166807e-08	UP	5.63696641173336	6.6061491429237e-08	Type II diabetes mellitus: C00238
hsa04022__43	1.81159124694623e-08	DOWN	-5.62969915808695	6.87672717780196e-08	cGMP-PKG signaling pathway: MAPK1
hsa04931__40	1.88949199756178e-08	UP	5.62243190444054	7.15797472463425e-08	Insulin resistance: PRKCZ
hsa03460__27	1.97064129581009e-08	UP	5.61516465079413	7.45037222299226e-08	Fanconi anemia pathway: BRCA1
hsa04933__12	2.09874422766128e-08	DOWN	-5.60426377032451	7.91875583087457e-08	AGE-RAGE signaling pathway in diabetic complications: EGR1
hsa05222__36	2.128290483648e-08	DOWN	-5.60184135244237	8.01414392539999e-08	Small cell lung cancer: PTGS2
hsa04010__107	2.14321464148038e-08	DOWN	-5.60063014350131	8.05420062268328e-08	MAPK signaling pathway: MAP3K2
hsa04020__42	2.34671956946755e-08	DOWN	-5.58488442726741	8.78383679487952e-08	Calcium signaling pathway: MYLK4
hsa04390__90	2.34671956946755e-08	DOWN	-5.58488442726741	8.78383679487952e-08	Hippo signaling pathway: BBC3
hsa05205__103	2.36312819128187e-08	DOWN	-5.58367321832634	8.82766972449032e-08	Proteoglycans in cancer: CCND1
hsa04370__14	2.42988336593696e-08	DOWN	-5.57882838256207	9.04109078137732e-08	VEGF signaling pathway: PTGS2
hsa04390__80	2.42988336593696e-08	DOWN	-5.57882838256207	9.04109078137732e-08	Hippo signaling pathway: BIRC2
hsa04022__66	2.48114719828886e-08	UP	5.57519475573886	9.2135881138039e-08	cGMP-PKG signaling pathway: PDE3A
hsa05161__32	2.49846723330771e-08	DOWN	-5.5739835467978	9.25960538734751e-08	Hepatitis B: STAT3
hsa05215__14	2.62303569202182e-08	DOWN	-5.56550508421032	9.70213398682875e-08	Prostate cancer: CCND1
hsa04213__62	2.65972000756257e-08	DOWN	-5.56308266632818	9.81849488056989e-08	Longevity regulating pathway - multiple species: CAT*
hsa05213__29	2.71568161794764e-08	DOWN	-5.55944903950497	1.00054230590659e-07	Endometrial cancer: CCND1
hsa05133__73	2.73458812807089e-08	DOWN	-5.5582378305639	1.0055364173474e-07	Pertussis: FOS
hsa04350__27	2.77278507548818e-08	UP	5.55581541268177	1.01759046032076e-07	TGF-beta signaling pathway: ACVR2A*
hsa04066__56	2.87055632652023e-08	DOWN	-5.54975936797642	1.05141819445059e-07	HIF-1 signaling pathway: TEK
hsa04064__4	2.89050807656701e-08	DOWN	-5.54854815903535	1.05666627935203e-07	NF-kappa B signaling pathway: BIRC2
hsa04022__65	2.91059434819113e-08	DOWN	-5.54733695009429	1.05988503493239e-07	cGMP-PKG signaling pathway: PDE2A
hsa04973__36	2.91059434819113e-08	DOWN	-5.54733695009429	1.05988503493239e-07	Carbohydrate digestion and absorption: SLC2A2
hsa05216__14	2.93081601871772e-08	UP	5.54612574115322	1.06518439055524e-07	Thyroid cancer: MAPK1*
hsa04261__62	3.03398644920709e-08	DOWN	-5.54006969644787	1.10055222742473e-07	Adrenergic signaling in cardiomyocytes: BCL2
hsa04072__3	3.16244722508607e-08	DOWN	-5.53280244280146	1.14493994912076e-07	Phospholipase D signaling pathway: MAPK1
hsa04014__68	3.18436415507351e-08	DOWN	-5.53159123386039	1.15065773988137e-07	Ras signaling pathway: RALGDS*
hsa04068__45	3.25100269156603e-08	DOWN	-5.52795760703719	1.17248254461662e-07	FoxO signaling pathway: RBL2
hsa04261__8 38	3.45913636528887e-08	DOWN	-5.51705672656757	1.24515655754364e-07	Adrenergic signaling in cardiomyocytes: ATP2A2 PLN
hsa04360__29	3.55573602519629e-08	DOWN	-5.5122118908033	1.27748145149978e-07	Axon guidance: RASA1
hsa05160__53	3.83507126935746e-08	UP	5.49888859245154	1.37259026954717e-07	Hepatitis C: EIF2S1
hsa05162__74	3.83507126935746e-08	UP	5.49888859245154	1.37259026954717e-07	Measles: EIF2S1
hsa05161__31	3.9418319390531e-08	DOWN	-5.49404375668727	1.40811829153627e-07	Hepatitis B: ELK1
hsa04152__44	3.96896913853686e-08	DOWN	-5.4928325477462	1.41512201353145e-07	AMPK signaling pathway: SLC2A4
hsa05140__62	3.99628746278409e-08	DOWN	-5.49162133880513	1.42216366336578e-07	Leishmaniasis: C00584
hsa04919__91	4.5203576483143e-08	DOWN	-5.46981957786589	1.59957665182346e-07	Thyroid hormone signaling pathway: PFKP
hsa04950__20	4.5203576483143e-08	UP	5.46981957786589	1.59957665182346e-07	Maturity onset diabetes of the young: NKX6-1
hsa05168__79	4.5203576483143e-08	UP	5.46981957786589	1.59957665182346e-07	Herpes simplex infection: EIF2S1
hsa05205__30	4.9396767077305e-08	DOWN	-5.454073861632	1.74467152891459e-07	Proteoglycans in cancer: FLNA
hsa04062__22 41	4.97344946835172e-08	DOWN	-5.45286265269093	1.75330423096302e-07	Chemokine signaling pathway: CRK PTK2B
hsa04210__119	5.11079255242379e-08	DOWN	-5.44801781692666	1.79834816591841e-07	Apoptosis: BCL2*
hsa03320__31	5.18083559030162e-08	DOWN	-5.44559539904452	1.81958692975266e-07	PPAR signaling pathway: CD36
hsa05161__213	5.36003801870541e-08	UP	5.43953935433918	1.87901332782602e-07	Hepatitis B: E2F1
hsa04350__34	5.47042763656791e-08	DOWN	-5.43590572751597	1.91414032199462e-07	TGF-beta signaling pathway: ROCK1
hsa05120__53	5.54524136249713e-08	DOWN	-5.43348330963384	1.9367116208424e-07	Epithelial cell signaling in Helicobacter pylori infection: GIT1
hsa04932__35	5.65932423516379e-08	DOWN	-5.42984968281063	1.97288872687806e-07	Non-alcoholic fatty liver disease (NAFLD): PRKAG2
hsa05110__46	6.01538625777781e-08	DOWN	-5.41894880234101	2.09313162562306e-07	Vibrio cholerae infection: PLCG1
hsa05132__13	6.05626334921403e-08	DOWN	-5.41773759339994	2.1034600431004e-07	Salmonella infection: FOS
hsa04728__32	6.13882650600418e-08	DOWN	-5.41531517551781	2.12820203040256e-07	Dopaminergic synapse: CREB3
hsa04010__12	6.3072369796077e-08	UP	5.41047033975353	2.18255953677401e-07	MAPK signaling pathway: PLA2G4B
hsa04068__46	6.35003397642317e-08	DOWN	-5.40925913081246	2.19332975031234e-07	FoxO signaling pathway: PLK4
hsa04919__18	6.43647360670174e-08	DOWN	-5.40683671293033	2.21910713889772e-07	Thyroid hormone signaling pathway: STAT1
hsa04012__22	6.56827408451689e-08	UP	5.40320308610712	2.25626819100681e-07	ErbB signaling pathway: EIF4EBP1
hsa05164__35	6.56827408451689e-08	DOWN	-5.40320308610712	2.25626819100681e-07	Influenza A: IL18
hsa04210__62	7.07428074865477e-08	DOWN	-5.38987978775537	2.42565210341648e-07	Apoptosis: TP53AIP1
hsa04919__104	7.56690451147119e-08	UP	5.37776769834468	2.58983853862557e-07	Thyroid hormone signaling pathway: MYC
hsa05214__52	7.77311897665822e-08	UP	5.3729228625804	2.65558010129833e-07	Glioma: E2F1*
hsa04064__2	7.9847712407496e-08	DOWN	-5.36807802681613	2.72293741585635e-07	NF-kappa B signaling pathway: BCL2L1
hsa05014__5	8.1471620604419e-08	UP	5.36444439999292	2.77328215789318e-07	Amyotrophic lateral sclerosis (ALS): TOMM40
hsa04020__18	8.31271961902035e-08	DOWN	-5.36081077316972	2.80929051716056e-07	Calcium signaling pathway: C00002
hsa04020__17	8.31271961902035e-08	DOWN	-5.36081077316972	2.80929051716056e-07	Calcium signaling pathway: C00004
hsa04020__15	8.31271961902035e-08	DOWN	-5.36081077316972	2.80929051716056e-07	Calcium signaling pathway: C13051
hsa05034__84	8.31274894912863e-08	DOWN	-5.36081077316972	2.80929051716056e-07	Alcoholism: FOSB
hsa04012__43	8.82929831708346e-08	DOWN	-5.3499098927001	2.97850117375221e-07	ErbB signaling pathway: PTK2
hsa04024__101	8.88857531040505e-08	UP	5.34869868375903	2.99312419502708e-07	cAMP signaling pathway: HCN4
hsa04152__62	8.94823752610118e-08	UP	5.34748747481796	3.00782438489161e-07	AMPK signaling pathway: EIF4EBP1
hsa05030__37	9.37686399543197e-08	DOWN	-5.33900901223048	3.14066442912953e-07	Cocaine addiction: PRKACA
hsa05205__22	9.37686399543197e-08	DOWN	-5.33900901223048	3.14066442912953e-07	Proteoglycans in cancer: PPP1R12A
hsa05205__352	9.63063665918336e-08	DOWN	-5.33416417646621	3.21992282608639e-07	Proteoglycans in cancer: ITGA5*
hsa03460__28	9.69512538024747e-08	UP	5.33295296752514	3.23572657006838e-07	Fanconi anemia pathway: RAD51C
hsa04210__56	9.76002066476422e-08	UP	5.33174175858407	3.25160972147021e-07	Apoptosis: BAX
hsa04210__106	1.00238320741696e-07	DOWN	-5.3268969228198	3.33358946325038e-07	Apoptosis: TUBA1B
hsa04022__60	1.03633144403376e-07	DOWN	-5.32084087811445	3.44040067727816e-07	cGMP-PKG signaling pathway: TRPC6*
hsa05205__129	1.09297530911576e-07	DOWN	-5.3111512065859	3.61567008068402e-07	Proteoglycans in cancer: AKT3*
hsa05211__46	1.09297530911576e-07	DOWN	-5.3111512065859	3.61567008068402e-07	Renal cell carcinoma: AKT3
hsa04014__41	1.12240954121772e-07	DOWN	-5.30630637082163	3.70651586634111e-07	Ras signaling pathway: RAC1*
hsa05200__96	1.15261019440194e-07	DOWN	-5.30146153505736	3.79956939523026e-07	Pathways in cancer: C00416
hsa04071__68	1.19146812873331e-07	DOWN	-5.29540549035201	3.92078566355498e-07	Sphingolipid signaling pathway: NFKB1
hsa04066__64	1.19939040357019e-07	DOWN	-5.29419428141094	3.93307952584362e-07	HIF-1 signaling pathway: LTBR
hsa04540__10	1.19939040357019e-07	UP	5.29419428141094	3.93307952584362e-07	Gap junction: C00533
hsa04370__39	1.28996911295144e-07	DOWN	-5.28087098305919	4.22273861190897e-07	VEGF signaling pathway: RAC1
hsa05221__35	1.29852415875646e-07	UP	5.27965977411812	4.24335112052762e-07	Acute myeloid leukemia: EIF4EBP1
hsa05120__50	1.33329651032501e-07	DOWN	-5.27481493835385	4.34941691475814e-07	Epithelial cell signaling in Helicobacter pylori infection: EGFR
hsa04064__113	1.35101878678868e-07	DOWN	-5.27239252047171	4.39959150845048e-07	NF-kappa B signaling pathway: CFLAR
hsa04550__47	1.40556357058353e-07	DOWN	-5.2651252668253	4.56929748983814e-07	Signaling pathways regulating pluripotency of stem cells: CTNNB1*
hsa04724__51	1.46223558503406e-07	UP	5.25785801317889	4.7453206636943e-07	Glutamatergic synapse: ADRBK1
hsa05164__20	1.50123803863194e-07	DOWN	-5.25301317741461	4.86349357687831e-07	Influenza A: ATF2
hsa04920__43	1.64582798877369e-07	DOWN	-5.23605625223965	5.32273802221302e-07	Adipocytokine signaling pathway: C00162
hsa04022__45	1.67851862016648e-07	DOWN	-5.23242262541644	5.41913485789145e-07	cGMP-PKG signaling pathway: CREB3
hsa04024__114	1.8759627937567e-07	DOWN	-5.21183207341828	6.04619912430332e-07	cAMP signaling pathway: HHIP
hsa04062__8 41	1.91306125424219e-07	DOWN	-5.20819844659507	6.15520906972787e-07	Chemokine signaling pathway: PXN PTK2B
hsa05205__319	1.93818647097415e-07	DOWN	-5.20577602871293	6.22538868198362e-07	Proteoglycans in cancer: KDR
hsa05030__78	2.01549061487566e-07	DOWN	-5.19850877506652	6.46263970196478e-07	Cocaine addiction: GRIA2
hsa04310__34	2.06867330345097e-07	DOWN	-5.19366393930225	6.6106073761639e-07	Wnt signaling pathway: FOSL1
hsa04727__47	2.06867330345097e-07	UP	5.19366393930225	6.6106073761639e-07	GABAergic synapse: CACNA1A*
hsa04151__24	2.22201286378356e-07	UP	5.18034064095049	7.08856056205316e-07	PI3K-Akt signaling pathway: MYC
hsa04932__28	2.34037174553553e-07	UP	5.17065096942194	7.45348899976485e-07	Non-alcoholic fatty liver disease (NAFLD): GSK3A
hsa04730__30	2.35558810512291e-07	DOWN	-5.16943976048088	7.48925558295423e-07	Long-term depression: C00025*
hsa04919__43	2.38630808606225e-07	UP	5.16701734259874	7.574109617755e-07	Thyroid hormone signaling pathway: TBC1D4
hsa04520__9 57	2.4331149252172e-07	UP	5.16338371577553	7.70965083386698e-07	Adherens junction: LEF1 CTNNB1
hsa04340__40	2.44891338347394e-07	DOWN	-5.16217250683446	7.73362730680256e-07	Hedgehog signaling pathway: SUFU
hsa05134__71	2.44891338347394e-07	UP	5.16217250683446	7.73362730680256e-07	Legionellosis: CXCL8
hsa04550__53 64	2.61244700828161e-07	DOWN	-5.15006041742378	8.23622135664622e-07	Signaling pathways regulating pluripotency of stem cells: SMAD1 SMAD4
hsa04390__52	2.62936877487802e-07	DOWN	-5.14884920848271	8.27568497151726e-07	Hippo signaling pathway: ITGB2
hsa05223__28	2.69812069907813e-07	UP	5.14400437271844	8.47787423673548e-07	Non-small cell lung cancer: RB1
hsa04720__32	2.7865049983904e-07	DOWN	-5.13794832801309	8.74097310847341e-07	Long-term potentiation: ITPR1
hsa04340__33	2.82263606992151e-07	DOWN	-5.13552591013095	8.83955529230419e-07	Hedgehog signaling pathway: HHIP*
hsa04630__34	2.99090149263508e-07	DOWN	-5.12462502966134	9.35092163837156e-07	Jak-STAT signaling pathway: AOX1
hsa04210__84	3.20973901260544e-07	DOWN	-5.11130173130958	1.00184378815376e-06	Apoptosis: FAS**
hsa03460__16 34	3.27205546421832e-07	UP	5.10766810448638	1.0196006993808e-06	Fanconi anemia pathway: FANCM STRA13
hsa05145__9	3.29308596503325e-07	DOWN	-5.10645689554531	1.02445505435389e-06	Toxoplasmosis: MAPK1
hsa04510__6 4 5	3.31424692675022e-07	DOWN	-5.10524568660424	1.02594233531527e-06	Focal adhesion: FLNA ITGB1 ITGA11
hsa04510__26 4 5	3.31424692675022e-07	DOWN	-5.10524568660424	1.02594233531527e-06	Focal adhesion: ACTN4 ITGB1 ITGA11
hsa04919__11	3.31424692675022e-07	DOWN	-5.10524568660424	1.02594233531527e-06	Thyroid hormone signaling pathway: CTNNB1
hsa05218__21	3.35696334959649e-07	UP	5.1028232687221	1.03575273134512e-06	Melanoma: RB1
hsa05220__40	3.35696334959649e-07	UP	5.1028232687221	1.03575273134512e-06	Chronic myeloid leukemia: RB1
hsa04010__61	3.3785203802011e-07	UP	5.10161205978103	1.04069504826195e-06	MAPK signaling pathway: ATF4
hsa04210__50	3.4002110107067e-07	DOWN	-5.10040085083997	1.04566227317805e-06	Apoptosis: SPTA1
hsa04919__38	3.48832551930519e-07	DOWN	-5.09555601507569	1.07100713247949e-06	Thyroid hormone signaling pathway: TP53
hsa05168__106 134	3.57864212627441e-07	DOWN	-5.09071117931142	1.09694429939146e-06	Herpes simplex infection: SRSF8 C1QBP
hsa05200__225	3.74215466513943e-07	DOWN	-5.08223271672394	1.14333473427593e-06	Pathways in cancer: PPARD
hsa05221__11	3.74215466513943e-07	DOWN	-5.08223271672394	1.14333473427593e-06	Acute myeloid leukemia: PPARD
hsa05205__140	3.83880326651213e-07	DOWN	-5.07738788095966	1.17095963275589e-06	Proteoglycans in cancer: MAPK1***
hsa04722__38	3.88802649756571e-07	DOWN	-5.07496546307752	1.18405215379675e-06	Neurotrophin signaling pathway: ATF4
hsa05211__31	4.30434710787891e-07	DOWN	-5.05558612002043	1.308716539758e-06	Renal cell carcinoma: SOS1
hsa04664__30	4.35931693091595e-07	DOWN	-5.05316370213829	1.32328861279339e-06	Fc epsilon RI signaling pathway: PRKCA
hsa04919__31	4.49972060242922e-07	DOWN	-5.04710765743295	1.36370564709105e-06	Thyroid hormone signaling pathway: ATP2A2
hsa04014__70	4.52832010413325e-07	DOWN	-5.04589644849188	1.3701632005904e-06	Ras signaling pathway: RIN1*
hsa04530__5 15	4.70363482051506e-07	DOWN	-5.03862919484547	1.42092119417167e-06	Tight junction: IGSF5 MPDZ
hsa04550__67	4.8241290522796e-07	UP	5.03378435908119	1.45498210100054e-06	Signaling pathways regulating pluripotency of stem cells: MYC*
hsa04919__39	4.94759763828112e-07	DOWN	-5.02893952331692	1.48982948114266e-06	Thyroid hormone signaling pathway: ESR1
hsa04921__55	5.07411102971542e-07	DOWN	-5.02409468755264	1.52548073997364e-06	Oxytocin signaling pathway: PTGS2*
hsa04115__40	5.13853197803531e-07	DOWN	-5.0216722696705	1.54238044516427e-06	p53 signaling pathway: PIDD1
hsa05031__11	5.40419233190393e-07	UP	5.01198259814196	1.61695499866998e-06	Amphetamine addiction: GRIN3A
hsa05031__54	5.40419233190393e-07	UP	5.01198259814196	1.61695499866998e-06	Amphetamine addiction: GRIN3A*
hsa05030__76	5.7911860916947e-07	DOWN	-4.9986592997902	1.72999024901341e-06	Cocaine addiction: PDYN
hsa05210__31	5.97579822712689e-07	DOWN	-4.99260325508486	1.78230553472562e-06	Colorectal cancer: BCL2
hsa05014__32 34	6.05122042679135e-07	DOWN	-4.99018083720272	1.80194028239952e-06	Amyotrophic lateral sclerosis (ALS): NEFM PRPH
hsa04360__51	6.4021255661304e-07	DOWN	-4.9792799567331	1.90040978495403e-06	Axon guidance: FYN
hsa04621__30 32	6.4021255661304e-07	DOWN	-4.9792799567331	1.90040978495403e-06	NOD-like receptor signaling pathway: PYCARD CASP1
hsa05215__24	6.73043864520377e-07	DOWN	-4.96959028520455	1.99471517576307e-06	Prostate cancer: CDKN1A
hsa04014__38	6.90062098275285e-07	DOWN	-4.96474544944028	2.04193178371537e-06	Ras signaling pathway: MAPK8
hsa04068__39	7.2988249457391e-07	UP	4.95384456897066	2.15636667815154e-06	FoxO signaling pathway: CCNB3
hsa04068__41	7.91331452950177e-07	DOWN	-4.93809885273677	2.33424144441661e-06	FoxO signaling pathway: CDKN2B
hsa04068__40	8.16268094026235e-07	DOWN	-4.93204280803143	2.40402468444404e-06	FoxO signaling pathway: CCND1
hsa03320__47	8.26453204447962e-07	DOWN	-4.92962039014929	2.43021216143618e-06	PPAR signaling pathway: PLTP
hsa04932__58	9.01254465233716e-07	UP	4.91266346497433	2.64602678152211e-06	Non-alcoholic fatty liver disease (NAFLD): BAX
hsa04115__50	9.23796799377857e-07	UP	4.90781862921005	2.70797844934632e-06	p53 signaling pathway: RCHY1
hsa05219__27	9.76519101733748e-07	DOWN	-4.89691774874044	2.85806758903071e-06	Bladder cancer: RPS6KA5
hsa04115__18	1.01326389731133e-06	UP	4.88965049509402	2.96099978701086e-06	p53 signaling pathway: CCNG1
hsa05164__77	1.01951601516776e-06	UP	4.88843928615296	2.97464377717425e-06	Influenza A: CASP9
hsa04310__33	1.02580525651246e-06	DOWN	-4.88722807721189	2.98835360773164e-06	Wnt signaling pathway: CCND1
hsa04380__51	1.03849595540454e-06	DOWN	-4.88480565932975	3.02064071239185e-06	Osteoclast differentiation: FOS*
hsa04730__7	1.05781574590825e-06	DOWN	-4.88117203250654	3.07208004105348e-06	Long-term depression: GNA13
hsa04261__14 16	1.07088728490681e-06	UP	4.87874961462441	3.10524260546281e-06	Adrenergic signaling in cardiomyocytes: TNNI3 TPM1
hsa05010__51	1.11787295188713e-06	DOWN	-4.87027115203693	3.23649195161159e-06	Alzheimer's disease: ATF6
hsa04913__19	1.18845056929439e-06	DOWN	-4.85815906262624	3.43553633800639e-06	Ovarian steroidogenesis: STAR
hsa04925__18	1.20307159884717e-06	DOWN	-4.8557366447441	3.47246011403046e-06	Aldosterone synthesis and secretion: PDE2A
hsa05132__8	1.21786560372954e-06	UP	4.85331422686197	3.50976912485859e-06	Salmonella infection: TJP1
hsa04024__43	1.22532808314775e-06	UP	4.8521030179209	3.52586748581106e-06	cAMP signaling pathway: MAPK8
hsa04740__33	1.45307242911353e-06	UP	4.81818916757098	4.17480595459378e-06	Olfactory transduction: CNGA3*
hsa04390__95	1.47081149770063e-06	DOWN	-4.81576674968884	4.21932031172441e-06	Hippo signaling pathway: AFP
hsa04068__68	1.55324680396933e-06	DOWN	-4.80486586921922	4.44901028149142e-06	FoxO signaling pathway: ATG12
hsa04152__87	1.57215982543604e-06	DOWN	-4.80244345133708	4.48949591488497e-06	AMPK signaling pathway: CD36
hsa04720__4 15	1.57215982543604e-06	DOWN	-4.80244345133708	4.48949591488497e-06	Long-term potentiation: CREBBP ATF4
hsa04066__52	1.61065218897681e-06	DOWN	-4.79759861557281	4.5924362110583e-06	HIF-1 signaling pathway: FLT1
hsa05205__195	1.68020384631773e-06	DOWN	-4.78912015298533	4.78348943519851e-06	Proteoglycans in cancer: CDKN1A
hsa04024__118	1.73164142072511e-06	UP	4.78306410827999	4.92247235936836e-06	cAMP signaling pathway: MYL9
hsa05220__15	1.78459054954226e-06	UP	4.77700806357464	5.06532574409353e-06	Chronic myeloid leukemia: MYC
hsa05200__199	1.79536547508387e-06	DOWN	-4.77579685463357	5.08055983084727e-06	Pathways in cancer: BCL2L1**
hsa05220__3	1.79536547508387e-06	DOWN	-4.77579685463357	5.08055983084727e-06	Chronic myeloid leukemia: BCL2L1
hsa04062__53	1.88384422294109e-06	DOWN	-4.76610718310503	5.32292224797942e-06	Chemokine signaling pathway: NFKB1
hsa05014__33 34	1.929640015272e-06	DOWN	-4.76126234734075	5.4441345175617e-06	Amyotrophic lateral sclerosis (ALS): NEFH PRPH
hsa04071__57	2.00034462644186e-06	UP	4.75399509369434	5.63515375274999e-06	Sphingolipid signaling pathway: BAX
hsa05211__42	2.01236811580061e-06	DOWN	-4.75278388475327	5.66053845746908e-06	Renal cell carcinoma: SLC2A1*
hsa04933__52	2.06115996440116e-06	DOWN	-4.747939048989	5.78911744859458e-06	AGE-RAGE signaling pathway in diabetic complications: FOXO1
hsa04724__5 71	2.08598003184626e-06	UP	4.74551663110686	5.85008429826735e-06	Glutamatergic synapse: GRIN3A DLG4
hsa04024__44 67	2.11108703076974e-06	UP	4.74309421322472	5.91167292223001e-06	cAMP signaling pathway: CREB3 CREBBP
hsa04724__13	2.16205034646413e-06	UP	4.73824937746045	6.04537589435432e-06	Glutamatergic synapse: GRM5
hsa04211__56	2.2012671510806e-06	DOWN	-4.73461575063724	6.14588555257126e-06	Longevity regulating pathway - mammal: CAT
hsa04064__36	2.26793433592303e-06	UP	4.7285597059319	6.32262406112667e-06	NF-kappa B signaling pathway: PLCG1
hsa05031__96	2.28149844939492e-06	DOWN	-4.72734849699083	6.35101568357489e-06	Amphetamine addiction: PDYN
hsa04960__13	2.32265976957053e-06	DOWN	-4.72371487016762	6.45603211098081e-06	Aldosterone-regulated sodium reabsorption: FXYD4
hsa03460__16 49	2.3645335967594e-06	UP	4.72008124334442	6.56271584684035e-06	Fanconi anemia pathway: FANCM C19orf40
hsa04666__49	2.40713170210062e-06	UP	4.71644761652121	6.6710921360576e-06	Fc gamma R-mediated phagocytosis: ARF6*
hsa05200__191	2.42149408226105e-06	DOWN	-4.71523640758014	6.70101234251622e-06	Pathways in cancer: CCND1*
hsa04919__26	2.45046604104396e-06	DOWN	-4.71281398969801	6.7712142516494e-06	Thyroid hormone signaling pathway: THRB
hsa03320__53	2.60038841037109e-06	DOWN	-4.70070190028732	7.1749336609211e-06	PPAR signaling pathway: ADIPOQ
hsa05161__57	2.72662639917253e-06	DOWN	-4.69101222875877	7.51221554845334e-06	Hepatitis B: STAT3*
hsa04530__4 53	2.77546518631775e-06	UP	4.68737860193557	7.63557699134854e-06	Tight junction: OCLN OCLN
hsa04012__37 7	2.87567303728031e-06	DOWN	-4.68011134828915	7.89969245182705e-06	ErbB signaling pathway: ERBB3 ERBB3
hsa03320__7	2.9443970555715e-06	DOWN	-4.67526651252488	8.07667455097642e-06	PPAR signaling pathway: AQP7
hsa04510__23 4 5	2.99697128030298e-06	DOWN	-4.67163288570167	8.20890529983862e-06	Focal adhesion: TLN1 ITGB1 ITGA11
hsa05205__434	3.06847269287042e-06	DOWN	-4.6667880499374	8.39251847147529e-06	Proteoglycans in cancer: CASP3
hsa04621__29	3.21641563375271e-06	DOWN	-4.65709837840885	8.78436769741474e-06	NOD-like receptor signaling pathway: CASP5
hsa04530__4 45	3.35145666364873e-06	UP	4.64861991582137	9.13989415238891e-06	Tight junction: OCLN TJP2
hsa04810__30	3.39102783552713e-06	DOWN	-4.64619749793923	9.23440768544271e-06	Regulation of actin cytoskeleton: VCL*
hsa04151__100	3.47151850492346e-06	DOWN	-4.64135266217496	9.42627640281962e-06	PI3K-Akt signaling pathway: PRKCA
hsa04310__57	3.47151850492346e-06	UP	4.64135266217496	9.42627640281962e-06	Wnt signaling pathway: SIAH1
hsa04910__26	3.5330854341091e-06	UP	4.63771903535175	9.57960682639393e-06	Insulin signaling pathway: RPS6
hsa04210__75	3.65937471500133e-06	UP	4.63045178170534	9.90773067649495e-06	Apoptosis: BAK1*
hsa04211__39	3.7024245987507e-06	UP	4.6280293638232	1.00098644907231e-05	Longevity regulating pathway - mammal: TP53*
hsa04520__44 47	3.72413119782755e-06	UP	4.62681815488213	1.00540840814913e-05	Adherens junction: ACTB TJP1
hsa04360__18	3.7679109596976e-06	DOWN	-4.624395737	1.01431299330541e-05	Axon guidance: PTK2
hsa05020__59	3.7679109596976e-06	DOWN	-4.624395737	1.01431299330541e-05	Prion diseases: CCL5
hsa04012__57	3.8569551426809e-06	DOWN	-4.61955090123572	1.03679809915557e-05	ErbB signaling pathway: ABL1
hsa04662__27	4.01765736352256e-06	DOWN	-4.61107243864824	1.07845402657984e-05	B cell receptor signaling pathway: NFATC1
hsa05214__23	4.08847684374316e-06	DOWN	-4.60743881182504	1.09433732042641e-05	Glioma: MAPK1
hsa05214__56	4.08847684374316e-06	DOWN	-4.60743881182504	1.09433732042641e-05	Glioma: MAPK1*
hsa04742__23 45	4.28316940972809e-06	UP	4.59774914029649	1.14481868006815e-05	Taste transduction: PKD1L3 PKD2L1
hsa04610__23	4.35852313568829e-06	UP	4.59411551347328	1.1633046835168e-05	Complement and coagulation cascades: BDKRB1
hsa04014__97	4.51294058965342e-06	DOWN	-4.58684825982687	1.20281069049061e-05	Ras signaling pathway: PAK4
hsa05205__324	4.56556781536028e-06	DOWN	-4.58442584194473	1.21511358711926e-05	Proteoglycans in cancer: KDR*
hsa04064__52	4.59210139873415e-06	DOWN	-4.58321463300366	1.22044675080926e-05	NF-kappa B signaling pathway: TRAF1
hsa04064__130	4.61878266614639e-06	DOWN	-4.5820034240626	1.22580404374139e-05	NF-kappa B signaling pathway: TNF*
hsa04950__11	4.6456124002359e-06	UP	4.58079221512153	1.23118557123318e-05	Maturity onset diabetes of the young: HNF4G
hsa04210__51	4.67259138755971e-06	DOWN	-4.57958100618046	1.23659143904573e-05	Apoptosis: LMNA
hsa04931__77	4.78117114110539e-06	UP	4.57473617041618	1.26354719748763e-05	Insulin resistance: PPP2R4**
hsa05133__59	4.86569029148902e-06	UP	4.57110254359298	1.28407753619493e-05	Pertussis: C3
hsa04270__17	5.18465607608907e-06	DOWN	-4.55777924524122	1.36633503043077e-05	Vascular smooth muscle contraction: ITPR1
hsa05014__54	5.39795648939967e-06	UP	4.54930078265374	1.42055465596386e-05	Amyotrophic lateral sclerosis (ALS): PPP3CA
hsa03320__57	5.49192031470507e-06	DOWN	-4.54566715583054	1.44326129668963e-05	PPAR signaling pathway: APOC3
hsa05222__34	5.55543062172905e-06	DOWN	-4.5432447379484	1.45791258913811e-05	Small cell lung cancer: CCND1
hsa04360__20	5.98571100702572e-06	DOWN	-4.52749902171451	1.56864030435165e-05	Axon guidance: ROCK1
hsa04330__12	6.15954952204568e-06	DOWN	-4.52144297700916	1.61194896266349e-05	Notch signaling pathway: HES1
hsa04620__18	6.1948922183573e-06	UP	4.5202317680681	1.61894332104219e-05	Toll-like receptor signaling pathway: CXCL11
hsa04630__30	6.23042891856876e-06	UP	4.51902055912703	1.62596888027649e-05	Jak-STAT signaling pathway: CDKN1A
hsa04950__13	6.3382131926483e-06	UP	4.51538693230382	1.6518034104003e-05	Maturity onset diabetes of the young: INS
hsa05032__25	6.37453608350998e-06	DOWN	-4.51417572336275	1.6589686012348e-05	Morphine addiction: C00575*
hsa05164__53	6.48470361086956e-06	DOWN	-4.51054209653955	1.68530540592308e-05	Influenza A: MAPK14
hsa04151__101	6.90444295072078e-06	UP	4.49721879818779	1.79191274922712e-05	PI3K-Akt signaling pathway: PKN3
hsa04066__50	7.02335258083072e-06	DOWN	-4.49358517136459	1.82025924129392e-05	HIF-1 signaling pathway: TF
hsa04211__29	7.35009689101046e-06	DOWN	-4.48389549983604	1.902318465318e-05	Longevity regulating pathway - mammal: EIF4E
hsa04064__128	7.60464235895791e-06	DOWN	-4.47662824618962	1.9654914707678e-05	NF-kappa B signaling pathway: IL1B*
hsa04024__111	7.77899879131694e-06	UP	4.47178341042535	2.00779378144018e-05	cAMP signaling pathway: JUN
hsa05162__20	7.82318140902382e-06	UP	4.47057220148428	2.01366546130901e-05	Measles: NFKB1
hsa05211__49	7.82318140902382e-06	DOWN	-4.47057220148428	2.01366546130901e-05	Renal cell carcinoma: TGFA*
hsa04530__14 20 43	8.00232283765617e-06	DOWN	-4.46572736572001	2.05695822324979e-05	Tight junction: CTNNA1 ACTB ACTN4
hsa04666__42	8.23176815527475e-06	UP	4.45967132101466	2.11016266899881e-05	Fc gamma R-mediated phagocytosis: MYO10
hsa05231__17	8.23176815527475e-06	DOWN	-4.45967132101466	2.11016266899881e-05	Choline metabolism in cancer: SLC44A3
hsa04213__60	8.32529575532743e-06	DOWN	-4.45724890313253	2.13123034390466e-05	Longevity regulating pathway - multiple species: CAT
hsa05032__30	8.75877700610643e-06	UP	4.44634802266291	2.23914857067673e-05	Morphine addiction: ADORA1
hsa04510__20 4 5	8.85812669381303e-06	DOWN	-4.44392560478077	2.25534147122963e-05	Focal adhesion: VASP ITGB1 ITGA11
hsa04916__7	8.85812669381303e-06	DOWN	-4.44392560478077	2.25534147122963e-05	Melanogenesis: TYRP1
hsa05200__183	8.85812669381303e-06	DOWN	-4.44392560478077	2.25534147122963e-05	Pathways in cancer: BMP2
hsa04110__96 97	8.90814973559162e-06	DOWN	-4.4427143958397	2.26194775042928e-05	Cell cycle: TFDP1 E2F4
hsa04152__58	8.90814973559162e-06	UP	4.4427143958397	2.26194775042928e-05	AMPK signaling pathway: SCD
hsa04932__31 133	8.95841332786136e-06	DOWN	-4.44150318689863	2.27164084251707e-05	Non-alcoholic fatty liver disease (NAFLD): PPARA RXRA
hsa05205__158	9.11095440660623e-06	DOWN	-4.43786956007543	2.30720799595864e-05	Proteoglycans in cancer: PDCD4
hsa04068__44	9.26594510066852e-06	DOWN	-4.43423593325222	2.34329890230904e-05	FoxO signaling pathway: CDKN1B
hsa05215__46	9.31816612756631e-06	UP	4.43302472431115	2.35333792388402e-05	Prostate cancer: MTOR
hsa04115__36	9.63744602814869e-06	UP	4.42575747066474	2.43070618615992e-05	p53 signaling pathway: EI24
hsa04115__1	9.8009789290403e-06	UP	4.42212384384154	2.46863799030385e-05	p53 signaling pathway: SIAH1
hsa05205__142	9.91146978685241e-06	DOWN	-4.4197014259594	2.49312606820558e-05	Proteoglycans in cancer: CTNNB1
hsa04066__30	1.04235705917117e-05	DOWN	-4.40880054548978	2.61843437724951e-05	HIF-1 signaling pathway: PDK1
hsa04622__44	1.06591939982152e-05	DOWN	-4.40395570972551	2.6740488014214e-05	RIG-I-like receptor signaling pathway: MAPK8
hsa05152__23	1.07188896835384e-05	UP	4.40274450078444	2.68543916204915e-05	Tuberculosis: PPP3CA
hsa05166__39	1.07789045109058e-05	DOWN	-4.40153329184337	2.69329276276489e-05	HTLV-I infection: RRAS2
hsa05200__80	1.07789045109058e-05	UP	4.40153329184337	2.69329276276489e-05	Pathways in cancer: TP53
hsa05145__8	1.10838226670456e-05	DOWN	-4.39547724713803	2.76580382355627e-05	Toxoplasmosis: NFKB1
hsa04152__35	1.12080811385241e-05	DOWN	-4.39305482925589	2.79310138717331e-05	AMPK signaling pathway: PFKFB1
hsa05217__19	1.12707079895474e-05	DOWN	-4.39184362031482	2.80127781909519e-05	Basal cell carcinoma: HHIP
hsa05223__37	1.12707079895474e-05	DOWN	-4.39184362031482	2.80127781909519e-05	Non-small cell lung cancer: CCND1*
hsa05131__12	1.15888858475354e-05	DOWN	-4.38578757560948	2.87655436030633e-05	Shigellosis: ARPC5
hsa05166__53 146	1.18495830811503e-05	DOWN	-4.3809427398452	2.93738345771523e-05	HTLV-I infection: CREB1 CRTC2
hsa04919__84	1.2115871947165e-05	UP	4.37609790408093	2.99943654660383e-05	Thyroid hormone signaling pathway: TP53*
hsa04742__67	1.25260385358717e-05	UP	4.36883065043452	3.09689821169776e-05	Taste transduction: PRKACA
hsa05210__23	1.25956750809883e-05	DOWN	-4.36761944149345	3.11002279594968e-05	Colorectal cancer: CCND1
hsa04360__4	1.33126615611539e-05	DOWN	-4.35550735208276	3.28274161068348e-05	Axon guidance: GNAI1*
hsa04150__31	1.34606566527419e-05	UP	4.35308493420063	3.31054631551074e-05	mTOR signaling pathway: EIF4E
hsa05231__21	1.34606566527419e-05	DOWN	-4.35308493420063	3.31054631551074e-05	Choline metabolism in cancer: PCYT1A
hsa04068__55	1.38375416698902e-05	DOWN	-4.34702888949528	3.39878964676127e-05	FoxO signaling pathway: ATM
hsa05152__15	1.43030946731798e-05	DOWN	-4.33976163584887	3.50397847339047e-05	Tuberculosis: CTSD
hsa05166__99	1.43030946731798e-05	DOWN	-4.33976163584887	3.50397847339047e-05	HTLV-I infection: JUN
hsa04068__43	1.43821248193704e-05	DOWN	-4.3385504269078	3.51875163223919e-05	FoxO signaling pathway: CDKN1A
hsa03320__62	1.47023491867603e-05	DOWN	-4.33370559114353	3.59242056201855e-05	PPAR signaling pathway: UBC
hsa04024__107 64	1.48651216196554e-05	UP	4.33128317326139	3.62747578225098e-05	cAMP signaling pathway: NFKBIA NFKB1
hsa04668__111	1.50295294694396e-05	DOWN	-4.32886075537925	3.66283863464033e-05	TNF signaling pathway: BAG4
hsa05140__21	1.527939574647e-05	DOWN	-4.32522712855605	3.71890992326646e-05	Leishmaniasis: NFKB1
hsa05110__12	1.54481681901906e-05	UP	4.32280471067391	3.75027235521553e-05	Vibrio cholerae infection: C00080
hsa05120__35	1.54481681901906e-05	UP	4.32280471067391	3.75027235521553e-05	Epithelial cell signaling in Helicobacter pylori infection: C00080
hsa04360__3	1.5533219445156e-05	DOWN	-4.32159350173284	3.76605410805781e-05	Axon guidance: GNAI1
hsa05220__6	1.57046630488554e-05	UP	4.3191710838507	3.80271415835042e-05	Chronic myeloid leukemia: TP53
hsa04066__29	1.59652145801021e-05	DOWN	-4.3155374570275	3.85586609203236e-05	HIF-1 signaling pathway: LDHA
hsa04810__32	1.59652145801021e-05	UP	4.3155374570275	3.85586609203236e-05	Regulation of actin cytoskeleton: PXN
hsa04360__6	1.61411992311434e-05	DOWN	-4.31311503914536	3.8883735070921e-05	Axon guidance: MAPK1
hsa04666__23	1.61411992311434e-05	UP	4.31311503914536	3.8883735070921e-05	Fc gamma R-mediated phagocytosis: RPS6KB1
hsa05166__33	1.66349260002829e-05	UP	3.92916180482661	4.00218001978637e-05	HTLV-I infection: HLA-A
hsa04261__66	1.6680315333874e-05	DOWN	-4.30584778549895	4.00796835196281e-05	Adrenergic signaling in cardiomyocytes: C01245
hsa05166__120	1.67718201159827e-05	UP	4.30463657655788	4.01967474463413e-05	HTLV-I infection: E2F1
hsa05200__226	1.67718201159827e-05	DOWN	-4.30463657655788	4.01967474463413e-05	Pathways in cancer: CDKN1A*
hsa04925__34	1.72365654826313e-05	DOWN	-4.29858053185254	4.12579701170244e-05	Aldosterone synthesis and secretion: STAR
hsa04742__54	1.73309090005582e-05	DOWN	-4.29736932291147	4.13783710445347e-05	Taste transduction: P2RX2*
hsa04742__40	1.73309090005582e-05	DOWN	-4.29736932291147	4.13783710445347e-05	Taste transduction: P2RX2
hsa04010__120	1.77135663483197e-05	UP	4.29252448714719	4.22383136655998e-05	MAPK signaling pathway: NFATC1
hsa05152__13	1.83025749032771e-05	DOWN	-4.28525723350078	4.3587500942025e-05	Tuberculosis: LAMP1
hsa04622__45	1.90133350839454e-05	DOWN	-4.2767787709133	4.52228564844726e-05	RIG-I-like receptor signaling pathway: MAPK14
hsa04722__85	1.91169934198029e-05	UP	4.27556756197223	4.54119224220097e-05	Neurotrophin signaling pathway: BAX
hsa04151__2	1.93259270959277e-05	DOWN	-4.2731451440901	4.57924552499976e-05	PI3K-Akt signaling pathway: EIF4E
hsa04360__59	1.93259270959277e-05	UP	4.2731451440901	4.57924552499976e-05	Axon guidance: MAPK1*
hsa04728__64	1.9643409901559e-05	UP	4.26951151726689	4.64861047922285e-05	Dopaminergic synapse: SCN1A
hsa03320__63	2.0183613064184e-05	DOWN	-4.26345547256155	4.77044137705682e-05	PPAR signaling pathway: DBI
hsa04360__21	2.02933379460501e-05	UP	4.26224426362048	4.79034949756634e-05	Axon guidance: PAK4
hsa04622__5 33	2.14222799275269e-05	DOWN	-4.25013217420979	5.05049736308946e-05	RIG-I-like receptor signaling pathway: MAVS TMEM173
hsa04213__71	2.1655130711784e-05	DOWN	-4.24770975632766	5.09899631672206e-05	Longevity regulating pathway - multiple species: SIRT1**
hsa04921__28	2.21280797702594e-05	UP	4.24286492056338	5.20383753295586e-05	Oxytocin signaling pathway: EEF2
hsa04917__48	2.23682252730401e-05	DOWN	-4.24044250268124	5.2537369110053e-05	Prolactin signaling pathway: CCND2
hsa04370__25	2.29794882562559e-05	DOWN	-4.2343864579759	5.38384768497567e-05	VEGF signaling pathway: PXN
hsa05211__27	2.29794882562559e-05	DOWN	-4.2343864579759	5.38384768497567e-05	Renal cell carcinoma: VEGFA*
hsa04211__57	2.33538415412481e-05	DOWN	-4.23075283115269	5.4647407541725e-05	Longevity regulating pathway - mammal: ATG5
hsa04750__51	2.38619250857106e-05	DOWN	-4.22590799538842	5.56975866286339e-05	Inflammatory mediator regulation of TRP channels: TRPV4
hsa04750__61	2.38619250857106e-05	DOWN	-4.22590799538842	5.56975866286339e-05	Inflammatory mediator regulation of TRP channels: TRPV4*
hsa04933__30	2.41200284633288e-05	UP	4.22348557750628	5.62301904250557e-05	AGE-RAGE signaling pathway in diabetic complications: CXCL8
hsa05205__69	2.46440422567517e-05	DOWN	-4.21864074174201	5.73806138791034e-05	Proteoglycans in cancer: MAPK1*
hsa04110__46	2.49100931060927e-05	UP	4.21621832385987	5.7928298200926e-05	Cell cycle: RB1
hsa04151__33	2.57247365785939e-05	UP	4.20895107021346	5.9748801027414e-05	PI3K-Akt signaling pathway: TP53
hsa04066__59	2.78736529943336e-05	DOWN	-4.19078293609743	6.46599925633985e-05	HIF-1 signaling pathway: NOS2
hsa04012__56	2.8022822543709e-05	DOWN	-4.18957172715636	6.49258736863493e-05	ErbB signaling pathway: JUN
hsa04014__67	2.86271248741359e-05	DOWN	-4.18472689139209	6.6244295121307e-05	Ras signaling pathway: RAPGEF5*
hsa04621__6	2.92438022284466e-05	DOWN	-4.17988205562781	6.75050422447803e-05	NOD-like receptor signaling pathway: NFKB1
hsa05168__9	2.92438022284466e-05	DOWN	-4.17988205562781	6.75050422447803e-05	Herpes simplex infection: NFKB1
hsa04390__59	2.95568559502777e-05	DOWN	-4.17745963774568	6.81439660497812e-05	Hippo signaling pathway: SERPINE1
hsa04071__1	2.98730932537173e-05	DOWN	-4.17503721986354	6.87886546859494e-05	Sphingolipid signaling pathway: MAPK1
hsa03320__41	3.00324152693967e-05	DOWN	-4.17382601092247	6.90708791813909e-05	PPAR signaling pathway: ANGPTL4
hsa04933__61	3.03534852189402e-05	DOWN	-4.17140359304033	6.97239593232134e-05	AGE-RAGE signaling pathway in diabetic complications: MMP2
hsa04068__51	3.05152408801748e-05	DOWN	-4.17019238409926	6.99245580656688e-05	FoxO signaling pathway: BCL6
hsa04068__56	3.05152408801748e-05	DOWN	-4.17019238409926	6.99245580656688e-05	FoxO signaling pathway: BCL6*
hsa05211__48	3.06778155126075e-05	DOWN	-4.1689811751582	7.02114681463941e-05	Renal cell carcinoma: JUN
hsa05164__24	3.13363821501299e-05	UP	4.16413633939392	7.15444253464083e-05	Influenza A: IRF7
hsa05205__145	3.13363821501299e-05	DOWN	-4.16413633939392	7.15444253464083e-05	Proteoglycans in cancer: PXN
hsa04310__20	3.15031105879973e-05	DOWN	-4.16292513045285	7.18377970811249e-05	Wnt signaling pathway: MAPK8
hsa05212__29	3.18390994959973e-05	DOWN	-4.16050271257071	7.2515961155126e-05	Pancreatic cancer: VEGFA
hsa04261__52	3.25213183991874e-05	UP	4.15565787680644	7.39800935497254e-05	Adrenergic signaling in cardiomyocytes: MAPK14
hsa04530__8	3.26940304267173e-05	DOWN	-4.15444666786537	7.4193337164012e-05	Tight junction: LLGL2
hsa04919__27	3.26940304267173e-05	UP	4.15444666786537	7.4193337164012e-05	Thyroid hormone signaling pathway: GATA4
hsa04922__24	3.28662183407001e-05	UP	4.1532354589243	7.44941185309716e-05	Glucagon signaling pathway: PFKL
hsa05031__8	3.32172905084678e-05	DOWN	-4.15081304104217	7.50186456235023e-05	Amphetamine addiction: DRD1
hsa04064__133	3.32174098769313e-05	DOWN	-4.15081304104217	7.50186456235023e-05	NF-kappa B signaling pathway: CXCL2
hsa04919__100	3.32174098769313e-05	DOWN	-4.15081304104217	7.50186456235023e-05	Thyroid hormone signaling pathway: CTNNB1*
hsa04510__20 69	3.33936313370037e-05	DOWN	-4.1496018321011	7.52357713216186e-05	Focal adhesion: VASP ACTB
hsa04728__71 72	3.33936313370037e-05	DOWN	-4.1496018321011	7.52357713216186e-05	Dopaminergic synapse: CLOCK ARNTL
hsa04722__73 77	3.42881400674258e-05	DOWN	-4.14354578739575	7.71585810619079e-05	Neurotrophin signaling pathway: NGFRAP1 YWHAE
hsa04919__44	3.46522769595774e-05	UP	4.14112336951362	7.78847229749354e-05	Thyroid hormone signaling pathway: PFKFB2
hsa04350__50	3.48357197461098e-05	DOWN	-4.13991216057255	7.8203485547121e-05	TGF-beta signaling pathway: AMHR2
hsa05034__62	3.57668513879341e-05	DOWN	-4.1338561158672	8.01979877779572e-05	Alcoholism: NPY
hsa04726__64	3.69154124414727e-05	UP	4.12658886222079	8.26746841210097e-05	Serotonergic synapse: CASP3
hsa04310__35	3.78992104649248e-05	DOWN	-4.12053281751545	8.46761194573052e-05	Wnt signaling pathway: JUN
hsa04611__25	3.78992104649248e-05	UP	4.12053281751545	8.46761194573052e-05	Platelet activation: ORAI1
hsa05161__126	3.80989339648548e-05	DOWN	-4.11932160857438	8.50212552493612e-05	Hepatitis B: MYC*
hsa04919__42	3.91126282844642e-05	DOWN	-4.11326556386904	8.71798677894522e-05	Thyroid hormone signaling pathway: SLC2A1
hsa04115__9	3.95252304488404e-05	DOWN	-4.1108431459869	8.79951516746104e-05	p53 signaling pathway: RPRM
hsa04933__35	4.01518870942964e-05	DOWN	-4.1072095191637	8.9284492130394e-05	AGE-RAGE signaling pathway in diabetic complications: CCND1
hsa04010__88 92	4.1217316032664e-05	DOWN	-4.10115347445835	9.15453153964252e-05	MAPK signaling pathway: ECSIT TRAF6
hsa05164__23	4.25312477561047e-05	DOWN	-4.09388622081194	9.43520832747588e-05	Influenza A: IRF3
hsa04015__11	4.38848518515079e-05	UP	4.08661896716553	9.71256026254222e-05	Rap1 signaling pathway: RAC1
hsa05152__68	4.38848518515079e-05	DOWN	-4.08661896716553	9.71256026254222e-05	Tuberculosis: CD74
hsa04660__26	4.4345062763663e-05	UP	4.08419654928339	9.80286740387326e-05	T cell receptor signaling pathway: GRB2
hsa03320__22	4.45768812094756e-05	DOWN	-4.08298534034232	9.84253346564098e-05	PPAR signaling pathway: ACADM
hsa05200__48	4.48098487466404e-05	UP	4.08177413140125	9.88235983508653e-05	Pathways in cancer: MTOR
hsa05221__41	4.62320862475971e-05	DOWN	-4.07450687775484	0.00010184066829922	Acute myeloid leukemia: MAPK1
hsa05152__69	4.79454612378568e-05	DOWN	-4.06602841516736	0.000105367861597582	Tuberculosis: HLA-DMA
hsa05219__12	4.79454612378568e-05	UP	4.06602841516736	0.000105367861597582	Bladder cancer: ERBB2
hsa04921__58	4.81950887061803e-05	DOWN	-4.06481720622629	0.000105792723923964	Oxytocin signaling pathway: MEF2C
hsa04213__61	5.10235610157328e-05	DOWN	-4.05149390787454	0.00011187079480579	Longevity regulating pathway - multiple species: ATG5
hsa05164__68	5.26319628191145e-05	UP	4.04422665422813	0.000115262771721581	Influenza A: EIF2S1
hsa04115__20	5.31786902947808e-05	UP	4.04180423634599	0.00011632451579033	p53 signaling pathway: RRM2B
hsa05220__21	5.513491858363e-05	DOWN	-4.03332577375851	0.000120463386068187	Chronic myeloid leukemia: NFKBIA
hsa04930__26	5.54198832490893e-05	UP	4.03211456481744	0.000120945366579604	Type II diabetes mellitus: INS*
hsa04621__28	5.62831722058663e-05	UP	4.02848093799424	0.000122686868416268	NOD-like receptor signaling pathway: CASP8
hsa04810__31	5.80481094960344e-05	DOWN	-4.02121368434782	0.000126387482900404	Regulation of actin cytoskeleton: MSN
hsa04261__15 16	5.95588035787851e-05	DOWN	-4.01515763964248	0.00012952661102377	Adrenergic signaling in cardiomyocytes: ACTC1 TPM1
hsa04024__59	6.017344360395e-05	UP	4.01273522176034	0.00013071202373621	cAMP signaling pathway: MLLT4
hsa04520__17	6.14207871251702e-05	DOWN	-4.00789038599607	0.0001332675046284	Adherens junction: SNAI1
hsa05031__97	6.26925839274685e-05	DOWN	-4.00304555023179	0.00013587008673554	Amphetamine addiction: ARC
hsa04917__46	6.56458718011953e-05	DOWN	-3.99214466976218	0.000142106674094984	Prolactin signaling pathway: GCK
hsa04360__111	6.63198048821928e-05	DOWN	-3.98972225188004	0.000143400360614086	Axon guidance: RHOA***
hsa05220__4	6.76873625156191e-05	DOWN	-3.98487741611576	0.000146189142720515	Chronic myeloid leukemia: PTPN11
hsa04213__54	6.83811065900327e-05	DOWN	-3.98245499823363	0.000147517909624192	Longevity regulating pathway - multiple species: SOD2*
hsa04950__21	6.94343492939995e-05	UP	3.97882137141042	0.000149618282480992	Maturity onset diabetes of the young: PKLR
hsa03320__9	7.05029275479588e-05	DOWN	-3.97518774458722	0.00015174685093083	PPAR signaling pathway: PCK1
hsa04012__21	7.23185390830575e-05	UP	3.96913169988187	0.000155476584596184	ErbB signaling pathway: GSK3B
hsa04340__46	7.38027785369422e-05	DOWN	-3.9642868641176	0.000158486195281045	Hedgehog signaling pathway: PRKACA
hsa05134__10	7.76404237769029e-05	DOWN	-3.95217477470691	0.000166536936389042	Legionellosis: NFKB1
hsa04740__21	7.96292696819294e-05	DOWN	-3.94611873000157	0.000170608207220462	Olfactory transduction: PDE1A
hsa05142__49	8.003277570161e-05	UP	3.9449075210605	0.000171277432281692	Chagas disease (American trypanosomiasis): ADCY1
hsa04920__12	8.16656781297463e-05	DOWN	-3.94006268529623	0.000174573161781335	Adipocytokine signaling pathway: C00165
hsa04022__63	8.6757638110727e-05	DOWN	-3.9255281780034	0.000185247275011427	cGMP-PKG signaling pathway: C00575
hsa04530__13 45 20	8.80765719529716e-05	DOWN	-3.9218945511802	0.000187850032576202	Tight junction: EPB41 TJP2 ACTB
hsa04014__35	9.16869529607079e-05	DOWN	-3.91220487965165	0.000195328553983186	Ras signaling pathway: NFKB1
hsa04723__7	9.73655867083072e-05	DOWN	-3.89767037235882	0.000207191322112015	Retrograde endocannabinoid signaling: ITPR1
hsa05032__13	0.000101840766302099	DOWN	-3.88676949188921	0.000216469230635344	Morphine addiction: PRKACA
hsa04014__100	0.000103375147015151	DOWN	-3.883135865066	0.000219482374284146	Ras signaling pathway: REL
hsa04972__21	0.000104410160795587	DOWN	-3.88071344718386	0.000221429675095833	Pancreatic secretion: KCNQ1
hsa05132__86	0.000107574192514591	DOWN	-3.87344619353745	0.000227882646826286	Salmonella infection: MYH9
hsa04670__14	0.000108648822587928	UP	3.87102377565531	0.000229899929777835	Leukocyte transendothelial migration: SIPA1
hsa04340__49	0.000113611218730047	DOWN	-3.8601228951857	0.000239860089880627	Hedgehog signaling pathway: CCND1
hsa04919__99	0.000113611218730047	DOWN	-3.8601228951857	0.000239860089880627	Thyroid hormone signaling pathway: WNT4
hsa05205__304	0.000118200983621272	DOWN	-3.85043322365715	0.000249270087793906	Proteoglycans in cancer: MAPK1*****
hsa04022__3	0.000119966793104187	DOWN	-3.84679959683394	0.000252710318657811	cGMP-PKG signaling pathway: MYL9
hsa05164__34	0.000123573292446468	DOWN	-3.83953234318753	0.000260015919940552	Influenza A: IL1B
hsa04068__59	0.000129175187999483	DOWN	-3.82863146271791	0.000271195729889417	FoxO signaling pathway: S1PR1
hsa04662__29	0.000129175187999483	DOWN	-3.82863146271791	0.000271195729889417	B cell receptor signaling pathway: RAC1
hsa05134__59	0.000130452142885889	UP	3.82620904483578	0.000273570955895742	Legionellosis: HSPA1A
hsa04924__23	0.000131740986578758	DOWN	-3.82378662695364	0.00027596579016888	Renin secretion: ITPR1
hsa05145__10	0.000132389898900327	DOWN	-3.82257541801257	0.000277016280661152	Toxoplasmosis: MAPK8
hsa04064__132	0.000137017322804338	DOWN	-3.81409695542509	0.000286379921634429	NF-kappa B signaling pathway: VCAM1
hsa04650__25	0.000139046785859626	DOWN	-3.81046332860188	0.000290298789589152	Natural killer cell mediated cytotoxicity: SH2D1B
hsa05231__34	0.000141104539329815	DOWN	-3.80682970177868	0.000294267957159514	Choline metabolism in cancer: PLD1
hsa05205__109	0.00014389285256473	DOWN	-3.8019848660144	0.00029941823916847	Proteoglycans in cancer: SMAD2
hsa05221__27	0.00014389285256473	DOWN	-3.8019848660144	0.00029941823916847	Acute myeloid leukemia: PIM2
hsa05200__187	0.000146732994022142	DOWN	-3.79714003025013	0.000304990371424342	Pathways in cancer: WNT16*
hsa05014__49	0.000151830654575913	DOWN	-3.78866156766265	0.000315237348008995	Amyotrophic lateral sclerosis (ALS): C00001
hsa04750__7	0.000154064799512078	UP	3.78502794083944	0.000319170626552586	Inflammatory mediator regulation of TRP channels: TRPV1
hsa04750__58	0.000154064799512078	UP	3.78502794083944	0.000319170626552586	Inflammatory mediator regulation of TRP channels: TRPV1**
hsa05166__114 112 113	0.000155573413174281	DOWN	-3.7826055229573	0.000321941016910214	HTLV-I infection: DLG1 CTNNB1 APC2
hsa04062__35 36 37	0.00015940288474762	DOWN	-3.77654947825196	0.000329502772762132	Chemokine signaling pathway: PARD3 PRKCZ TIAM1
hsa04068__13	0.000164115340650239	DOWN	-3.76928222460555	0.000338871126463515	FoxO signaling pathway: PCK1
hsa04917__71	0.000165715071676027	DOWN	-3.76685980672341	0.000341798704368007	Prolactin signaling pathway: CCND1*
hsa04115__29	0.000168142198107774	DOWN	-3.76322617990021	0.000346424550706698	p53 signaling pathway: IGF1
hsa04611__7	0.000168958644025986	DOWN	-3.76201497095914	0.000347725402108246	Platelet activation: ITPR1
hsa04360__131	0.00016977881803692	DOWN	-3.76080376201807	0.000349031071215944	Axon guidance: RAC1****
hsa04115__19	0.000171430413656839	UP	3.75838134413593	0.000351656929324454	p53 signaling pathway: RFWD2
hsa05168__123	0.000171430413656839	UP	3.75838134413593	0.000351656929324454	Herpes simplex infection: CYCS
hsa04913__35	0.000172261867078929	DOWN	-3.75717013519486	0.000352977151844392	Ovarian steroidogenesis: HSD17B2
hsa04064__94	0.000173936165141814	DOWN	-3.75474771731273	0.000356019666995065	NF-kappa B signaling pathway: BCL2L1*
hsa04310__13	0.000176476332124337	DOWN	-3.75111409048952	0.000360825928249868	Wnt signaling pathway: NFATC1
hsa05030__80 81	0.000179917515605084	UP	3.74626925472525	0.000367461969371688	Cocaine addiction: GRIN3A DLG4
hsa04151__35	0.000182539700219309	DOWN	-3.74263562790204	0.000372412700013117	PI3K-Akt signaling pathway: CCND1
hsa04012__31	0.000186990005418533	UP	3.7365795831967	0.000381078329914775	ErbB signaling pathway: BAD
hsa05132__41	0.000189708821339443	DOWN	-3.73294595637349	0.00038620029826307	Salmonella infection: ACTB*
hsa05145__11	0.000192464985204102	DOWN	-3.72931232955029	0.000391387129002714	Toxoplasmosis: MAPK14
hsa04062__44	0.000199999550241561	DOWN	-3.71962265802174	0.000405830620846537	Chemokine signaling pathway: MAPK1
hsa04621__4 7 8	0.000199999550241561	DOWN	-3.71962265802174	0.000405830620846537	NOD-like receptor signaling pathway: IKBKG CHUK IKBKB
hsa05169__31	0.000200960620121993	UP	3.71841144908067	0.000407340890193339	Epstein-Barr virus infection: MYC
hsa04920__5	0.000205831396036023	DOWN	-3.71235540437532	0.000416764216758283	Adipocytokine signaling pathway: NFKBIA
hsa04728__68	0.00020681876456438	DOWN	-3.71114419543426	0.000418312657283606	Dopaminergic synapse: CACNA1C
hsa04380__72	0.00020781058054735	DOWN	-3.70993298649319	0.000419866753600507	Osteoclast differentiation: MAPK1
hsa04310__32	0.000217977471152062	DOWN	-3.6978208970825	0.000439935196879402	Wnt signaling pathway: PPARD
hsa04923__38	0.000228609987398616	UP	3.68570880767181	0.000460899320087983	Regulation of lipolysis in adipocytes: PDE3B
hsa05211__45	0.000229699600197957	DOWN	-3.68449759873075	0.000462599730730934	Renal cell carcinoma: ETS1
hsa05211__22	0.000235221158993444	DOWN	-3.6784415540254	0.000473212588596019	Renal cell carcinoma: TGFA
hsa03320__64	0.000243160847647417	DOWN	-3.66996309143792	0.000488140205907581	PPAR signaling pathway: APOA5
hsa04932__7	0.000243160847647417	UP	3.66996309143792	0.000488140205907581	Non-alcoholic fatty liver disease (NAFLD): SREBF1
hsa04918__10	0.000244315400912824	DOWN	-3.66875188249685	0.000489934512609601	Thyroid hormone synthesis: TG
hsa05016__52	0.00025980021150145	UP	3.65300616626296	0.000520431340523693	Huntington's disease: CASP3
hsa04064__53	0.000262262623267565	DOWN	-3.65058374838082	0.000524804546453412	NF-kappa B signaling pathway: CXCL8
hsa04750__39	0.000263502018691207	DOWN	-3.64937253943976	0.000526723716085933	Inflammatory mediator regulation of TRP channels: C01245*
hsa04621__33 35	0.000264746903643359	UP	3.64816133049869	0.000528649768274039	NOD-like receptor signaling pathway: NLRC4 PYCARD
hsa04062__43	0.000269781789585467	DOWN	-3.64331649473441	0.000538131616381202	Chemokine signaling pathway: STAT1
hsa04210__105	0.000277502664259229	DOWN	-3.636049241088	0.00055294539357698	Apoptosis: ACTB
hsa04010__58	0.000294947139567415	UP	3.62030352485411	0.000587082283100819	MAPK signaling pathway: CDC25B
hsa04115__22	0.00031195657066048	DOWN	-3.60576901756129	0.000620281900815918	p53 signaling pathway: STEAP3
hsa04724__3	0.000325311692252343	DOWN	-3.59486813709167	0.000645470612188124	Glutamatergic synapse: GRIK1
hsa05162__101	0.000325311692252343	UP	3.59486813709167	0.000645470612188124	Measles: CDKN1B
hsa04115__55	0.000334510377643977	UP	3.58760088344526	0.000663022151469443	p53 signaling pathway: SHISA5
hsa04022__58	0.000339200456550424	DOWN	-3.58396725662205	0.000671609755382769	cGMP-PKG signaling pathway: MYH7
hsa05169__11	0.000339811239055953	UP	3.19638039548009	0.000672110861248565	Epstein-Barr virus infection: HLA-A
hsa04930__8	0.000340777439012582	UP	3.58275604768098	0.000673313152370812	Type II diabetes mellitus: C00022
hsa04710__23	0.000342361278443712	DOWN	-3.58154483873991	0.00067573197709636	Circadian rhythm: BHLHE41
hsa04976__16	0.000343952002325362	DOWN	-3.58033362979885	0.000678159299443185	Bile secretion: CFTR
hsa04066__37	0.000360244003196178	DOWN	-3.56822154038816	0.000709537192878008	HIF-1 signaling pathway: PDHA1
hsa05205__144	0.000363587815684781	DOWN	-3.56579912250602	0.000715373304368277	Proteoglycans in cancer: NUDT16L1
hsa05221__5	0.000372074744365878	UP	3.55974307780068	0.000731305904459713	Acute myeloid leukemia: SPI1
hsa04730__8	0.000375521086066396	DOWN	-3.55732065991854	0.000737308381106331	Long-term depression: GNA13*
hsa04015__95	0.00040233576965886	UP	3.53915252580251	0.000788309604993742	Rap1 signaling pathway: THBS1
hsa05200__213	0.00040233576965886	UP	3.53915252580251	0.000788309604993742	Pathways in cancer: CSF2RA
hsa05150__69	0.000413554241348225	UP	3.5318852721561	0.000809446270305536	Staphylococcus aureus infection: FPR2
hsa05134__7	0.000415452152604255	DOWN	-3.53067406321503	0.000812314874863055	Legionellosis: IL18
hsa05200__209	0.000425064333970869	DOWN	-3.52461801850969	0.000830245201175948	Pathways in cancer: FIGF**
hsa05150__13	0.000434883858454727	UP	3.51856197380435	0.00084854285569723	Staphylococcus aureus infection: C5AR1
hsa04024__112	0.000451036643767097	DOWN	-3.5088723022758	0.000879147151077153	cAMP signaling pathway: GLI1
hsa05222__32	0.000455161428177756	DOWN	-3.50644988439366	0.000886267692793785	Small cell lung cancer: BIRC8
hsa05010__49	0.00045723699548204	UP	3.50523867545259	0.000889387489141567	Alzheimer's disease: EIF2AK3
hsa04115__25	0.000461414652124079	DOWN	-3.50281625757045	0.000894734913664752	p53 signaling pathway: CD82
hsa05168__122	0.000461414652124079	UP	3.50281625757045	0.000894734913664752	Herpes simplex infection: CASP3
hsa05231__48	0.000461414652124079	DOWN	-3.50281625757045	0.000894734913664752	Choline metabolism in cancer: WAS
hsa04210__60	0.000469877023413954	UP	3.49797142180618	0.000909267690004964	Apoptosis: BBC3
hsa04650__35	0.000469877023413954	UP	3.49797142180618	0.000909267690004964	Natural killer cell mediated cytotoxicity: BID
hsa04261__4	0.000472015123458756	DOWN	-3.49676021286511	0.000912465449566875	Adrenergic signaling in cardiomyocytes: SLC8A1
hsa04068__67	0.000516730228636096	DOWN	-3.47253603404374	0.000997878827962204	FoxO signaling pathway: GABARAP
hsa04913__40	0.0005454228775792	DOWN	-3.45800152675091	0.00105220696814304	Ovarian steroidogenesis: HSD17B1
hsa04620__40	0.000547879737133984	DOWN	-3.45679031780985	0.0010558625908459	Toll-like receptor signaling pathway: CCL5
hsa03320__46	0.000560319424455731	DOWN	-3.4507342731045	0.00107872971163147	PPAR signaling pathway: APOA2
hsa05215__8	0.000562838718933365	DOWN	-3.44952306416343	0.001082470780835	Prostate cancer: NFKBIA
hsa04620__19	0.000588618409231868	UP	3.43741097475275	0.00112973849943481	Toll-like receptor signaling pathway: CXCL10
hsa05211__3	0.000588618409231868	DOWN	-3.43741097475275	0.00112973849943481	Renal cell carcinoma: VEGFA
hsa04064__142	0.000596564085767455	DOWN	-3.43377734792954	0.00114382032362964	NF-kappa B signaling pathway: NFKB2*
hsa05169__93	0.000612755809256565	UP	3.42651009428313	0.00117366785483495	Epstein-Barr virus infection: PLCG1
hsa04727__8	0.000632162707100249	DOWN	-3.41803163169565	0.00120837612069315	GABAergic synapse: ADCY1
hsa04727__35	0.000632162707100249	DOWN	-3.41803163169565	0.00120837612069315	GABAergic synapse: PRKACA
hsa05321__46	0.00065504151140558	DOWN	-3.4083419601671	0.00125083638204378	Inflammatory bowel disease (IBD): IFNG*
hsa04014__104	0.000672703379767444	DOWN	-3.40107470652069	0.00128325852851069	Ras signaling pathway: BRAP*
hsa05221__13	0.00068472283917978	DOWN	-3.39622987075641	0.00130486228683449	Acute myeloid leukemia: NFKB1
hsa04622__11	0.00071250016743405	UP	3.3853289902868	0.00135642129139674	RIG-I-like receptor signaling pathway: IRF7
hsa03320__66	0.000718813447246711	DOWN	-3.38290657240466	0.00136705512892365	PPAR signaling pathway: UCP1
hsa04014__63	0.000731596214570127	DOWN	-3.37806173664039	0.00138995883435518	Ras signaling pathway: TIAM1*
hsa05215__9	0.000751166768377053	DOWN	-3.37079448299397	0.00142569935129342	Prostate cancer: CDKN1B
hsa05221__26	0.000757797580932779	UP	3.36837206511184	0.00143683315294923	Acute myeloid leukemia: BAD
hsa04750__40	0.000788314278684648	DOWN	-3.35747118464222	0.00149318803391981	Inflammatory mediator regulation of TRP channels: C00219
hsa04064__137	0.000809288259427941	UP	3.35020393099581	0.00153137224518137	NF-kappa B signaling pathway: ICAM1
hsa05161__195	0.000816393868233271	DOWN	-3.34778151311367	0.00154326366037255	Hepatitis B: IL6
hsa04010__87	0.000830779059303966	DOWN	-3.3429366773494	0.00156887824365041	MAPK signaling pathway: STK3
hsa04210__63	0.00083805950152405	DOWN	-3.34051425946726	0.00158103795518443	Apoptosis: FAS*
hsa05200__202	0.000875357632468052	DOWN	-3.32840217005657	0.00164974623009776	Pathways in cancer: FIGF*
hsa05211__4	0.000898469237527788	DOWN	-3.32113491641016	0.00169160691113699	Renal cell carcinoma: SLC2A1
hsa04610__57	0.000906297935487691	DOWN	-3.31871249852802	0.00170463845924061	Complement and coagulation cascades: PLAUR
hsa05010__37	0.000910235947853807	UP	3.31750128958695	0.0017103333460173	Alzheimer's disease: MAPT
hsa04012__35	0.000918159588385501	DOWN	-3.31507887170482	0.00172349836820815	ErbB signaling pathway: CBLC
hsa05205__337	0.000942315635330457	DOWN	-3.3078116180584	0.00176707692493606	Proteoglycans in cancer: CTNNB1**
hsa04370__38	0.000950497595048202	UP	3.30538920017627	0.00178064305193975	VEGF signaling pathway: BAD
hsa04550__9	0.000967059286532946	UP	3.30054436441199	0.00180986493963686	Signaling pathways regulating pluripotency of stem cells: HNF1A
hsa04068__66	0.000971241262611431	DOWN	-3.29933315547092	0.00181407786525535	FoxO signaling pathway: BNIP3
hsa04910__20	0.000971241262611431	UP	3.29933315547092	0.00181407786525535	Insulin signaling pathway: PKLR
hsa04110__10 11 12 13 14 9 15 16 17 18 19 20	0.000996686843491984	UP	3.29206590182451	0.00185975628492695	Cell cycle: ORC3 ORC5 ORC4 ORC2 ORC1 ORC6 MCM7 MCM6 MCM5 MCM4 MCM3 MCM2
hsa05200__76	0.0010009873001131	DOWN	-3.29085469288344	0.00186592771519099	Pathways in cancer: RAC1
hsa04742__34	0.00101399195271563	UP	3.28722106606024	0.00188829621323358	Taste transduction: GRM1
hsa04210__58	0.00102274841465837	UP	3.2847986481781	0.00190271710014167	Apoptosis: BID*
hsa04972__42	0.00104047166946394	DOWN	-3.27995381241383	0.0019337747447307	Pancreatic secretion: CFTR
hsa04370__37	0.00104943947842662	UP	3.27753139453169	0.00194851460470713	VEGF signaling pathway: CASP9
hsa05200__196	0.00110949555870375	UP	3.2617856782978	0.00205798830681575	Pathways in cancer: TRAF1
hsa04932__14	0.00111901212353365	UP	3.25936326041566	0.00207359347151846	Non-alcoholic fatty liver disease (NAFLD): PKLR
hsa05218__14	0.00113342855543523	UP	3.25572963359245	0.00209823867552985	Melanoma: BAD
hsa04620__87	0.00114801651576058	DOWN	-3.25209600676925	0.00212315259164776	Toll-like receptor signaling pathway: CCL4L1
hsa04024__116	0.00116773714457461	UP	3.24725117100497	0.00215750058471552	cAMP signaling pathway: ACOX1
hsa04066__49	0.0011928281137487	DOWN	-3.24119512629963	0.00219953290062199	HIF-1 signaling pathway: EPO
hsa04925__33	0.0011928281137487	DOWN	-3.24119512629963	0.00219953290062199	Aldosterone synthesis and secretion: CYP11B2
hsa05169__118	0.00121325850284041	UP	3.23635029053536	0.0022350124772913	Epstein-Barr virus infection: MDM2
hsa04810__29	0.001228792883292	DOWN	-3.23271666371215	0.00226141217209175	Regulation of actin cytoskeleton: ACTN4
hsa04115__15	0.00124451077925982	UP	3.22908303688894	0.00228809760687789	p53 signaling pathway: TSC2
hsa04920__1	0.00126041414872853	UP	3.22544941006574	0.00231507154003998	Adipocytokine signaling pathway: C00195
hsa04921__53	0.00130374497999902	DOWN	-3.21575973853719	0.00239232111075993	Oxytocin signaling pathway: RGS2
hsa04921__65	0.00134844696750869	DOWN	-3.20607006700864	0.00247193351409642	Oxytocin signaling pathway: TRPM2
hsa04921__57	0.00138871666525594	DOWN	-3.19759160442116	0.00254327350293949	Oxytocin signaling pathway: FOS
hsa04970__21	0.00140042433414574	DOWN	-3.19516918653902	0.0025622174526386	Salivary secretion: ITPR1
hsa04668__141	0.00144212161083677	DOWN	-3.18669072395154	0.00263594018167538	TNF signaling pathway: JUN*
hsa04211__52	0.00145424360394688	DOWN	-3.18426830606941	0.00265293566195747	Longevity regulating pathway - mammal: PPARG
hsa04670__73	0.00145424360394688	DOWN	-3.18426830606941	0.00265293566195747	Leukocyte transendothelial migration: MYL12B*
hsa04924__52	0.00148496060477659	UP	3.17821226136406	0.00270634430298275	Renin secretion: KCNJ2
hsa04620__66	0.00150367662089123	UP	3.17457863454086	0.00273779880877385	Toll-like receptor signaling pathway: CASP8
hsa04012__65	0.00154819552815592	UP	3.16610017195338	0.00281340367253866	ErbB signaling pathway: MYC
hsa05221__6	0.00154819552815592	UP	3.16610017195338	0.00281340367253866	Acute myeloid leukemia: CEBPA
hsa04024__115	0.00157417673254238	UP	3.1612553361891	0.00285785321782332	cAMP signaling pathway: F2R
hsa05152__9	0.00158731732892864	DOWN	-3.15883291830696	0.00287892785816305	Tuberculosis: TCIRG1
hsa04664__3 4 5	0.00162734393928872	DOWN	-3.15156566466055	0.00294867816964659	Fc epsilon RI signaling pathway: FCER1G MS4A2 FCER1A
hsa04976__95 96	0.00168216080177774	UP	3.141875993132	0.00304506757855527	Bile secretion: SLC51A SLC51B
hsa04380__20	0.00169613420820526	UP	3.13945357524987	0.00306740729279853	Osteoclast differentiation: MAP2K1
hsa04924__31	0.00174586103379485	UP	3.13097511266239	0.00315127876767268	Renin secretion: C02135
hsa04062__33	0.00174586545883303	DOWN	-3.13097511266239	0.00315127876767268	Chemokine signaling pathway: WAS
hsa04950__5	0.00176758644837729	DOWN	-3.12734148583918	0.00318742316362852	Maturity onset diabetes of the young: GCK
hsa05166__136 139	0.00177488180593004	UP	3.12613027689811	0.00319750998402929	HTLV-I infection: TP53 TBPL2
hsa05222__39	0.00179693427616161	DOWN	-3.12249665007491	0.00323413745680811	Small cell lung cancer: BCL2L1
hsa04024__110	0.00181177553271733	UP	3.12007423219277	0.00325772844590992	cAMP signaling pathway: FOS
hsa05110__17	0.00181923832889377	DOWN	-3.1188630232517	0.00326801990438948	Vibrio cholerae infection: C00698*
hsa04380__32	0.00183424873478276	DOWN	-3.11644060536956	0.00329183703214594	Osteoclast differentiation: AKT3
hsa04917__40	0.0018722739865995	DOWN	-3.11038456066422	0.00335687292063022	Prolactin signaling pathway: TH
hsa05016__55	0.00195849151456494	UP	3.09706126231247	0.00350810825154197	Huntington's disease: TGM2
hsa05222__35	0.00203172796218351	DOWN	-3.08616038184285	0.00363582556280269	Small cell lung cancer: NOS2
hsa05160__58	0.00206507713666126	UP	3.08131554607857	0.00369198852501096	Hepatitis C: EIF3E
hsa04742__37	0.00209890720067028	UP	3.0764707103143	0.00374890364074093	Taste transduction: P2RY4
hsa05215__39	0.0021246489420588	UP	3.07283708349109	0.00379127764684567	Prostate cancer: RB1
hsa04010__57	0.00217696035208692	DOWN	-3.06556982984468	0.0038809378572783	MAPK signaling pathway: NLK
hsa05200__222	0.00222145224396879	UP	3.05951378513934	0.00395650120039559	Pathways in cancer: CASP9*
hsa04370__15	0.00224854580171563	DOWN	-3.05588015831613	0.00400096359983302	VEGF signaling pathway: PLA2G4B
hsa05212__19	0.0023222821751435	UP	3.04619048678758	0.00412825752799871	Pancreatic cancer: MAPK8
hsa05321__55	0.00235049954437763	DOWN	-3.04255685996438	0.00417446941766121	Inflammatory bowel disease (IBD): IL4*
hsa05231__39	0.00239822697033595	UP	3.03650081525903	0.00425521102668673	Choline metabolism in cancer: EIF4EBP1
hsa04810__8 79	0.00243704584940018	DOWN	-3.03165597949476	0.00431187302356209	Regulation of actin cytoskeleton: ARPC5 ACTB
hsa04810__8 82	0.00243704584940018	DOWN	-3.03165597949476	0.00431187302356209	Regulation of actin cytoskeleton: ARPC5 ACTB*
hsa05120__19	0.00243704584940018	DOWN	-3.03165597949476	0.00431187302356209	Epithelial cell signaling in Helicobacter pylori infection: CXCL1
hsa04742__31	0.00248637788225033	DOWN	-3.02559993478942	0.00439501791227504	Taste transduction: C00076*
hsa04933__63	0.00251641393832583	DOWN	-3.02196630796621	0.00444393025386676	AGE-RAGE signaling pathway in diabetic complications: SELE
hsa04915__30	0.00254678156152101	DOWN	-3.018332681143	0.00449333573154739	Estrogen signaling pathway: CREB3*
hsa04360__81	0.00267163322714511	DOWN	-3.00379817385018	0.00470919215178768	Axon guidance: FYN*
hsa04380__69	0.00268228598871671	UP	3.00258696490911	0.00471911551760178	Osteoclast differentiation: NFKB2
hsa04972__18	0.00268228598871671	DOWN	-3.00258696490911	0.00471911551760178	Pancreatic secretion: PRKCA
hsa05168__27	0.00276891562773538	DOWN	-2.99289729338056	0.00486697143546752	Herpes simplex infection: IRF3
hsa04620__86	0.00285809378230753	DOWN	-2.98320762185201	0.00501902637098678	Toll-like receptor signaling pathway: IL12A
hsa04210__4	0.00289220612663164	DOWN	-2.97957399502881	0.00507418796633133	Apoptosis: DFFA
hsa04724__26	0.0029967850270915	DOWN	-2.96867311455919	0.0052527603226725	Glutamatergic synapse: PRKACA
hsa05212__31	0.00310480282873889	DOWN	-2.95777223408957	0.00543702191537779	Pancreatic cancer: RAC1*
hsa04068__49	0.00315394060708099	DOWN	-2.9529273983253	0.00551792774739774	FoxO signaling pathway: BCL2L11
hsa05032__4	0.00322897738462256	DOWN	-2.94566014467889	0.00564395209833098	Morphine addiction: ADCY1
hsa04151__51	0.00339716715711707	UP	2.929914428445	0.0059269053743946	PI3K-Akt signaling pathway: NOS3
hsa04921__56	0.00339716715711707	DOWN	-2.929914428445	0.0059269053743946	Oxytocin signaling pathway: JUN
hsa04917__75	0.00341042954567631	DOWN	-2.92870321950393	0.00594452422664729	Prolactin signaling pathway: CCND1**
hsa04620__12	0.00342373905330032	DOWN	-2.92749201056286	0.00596219247558044	Toll-like receptor signaling pathway: NFKB1
hsa04620__22	0.00345050001737449	DOWN	-2.92506959268072	0.00599767764352143	Toll-like receptor signaling pathway: CD86
hsa05161__78	0.00345050001737449	DOWN	-2.92506959268072	0.00599767764352143	Hepatitis B: TNF
hsa04660__41 46	0.00358718262303472	DOWN	-2.91295750327003	0.00622949736477101	T cell receptor signaling pathway: GRAP2 LCP2
hsa05133__24	0.00365735463360814	DOWN	-2.90690145856469	0.00634549340401633	Pertussis: NFKB1
hsa04950__7	0.00377222962076475	UP	2.89721178703614	0.00653876333710052	Maturity onset diabetes of the young: FOXA3
hsa03320__21	0.00383088824765757	DOWN	-2.89236695127187	0.00663432167497564	PPAR signaling pathway: ACAA1
hsa05200__203	0.0039506985495952	DOWN	-2.88267727974332	0.00683550881647272	Pathways in cancer: TGFA*
hsa05150__35	0.00399644130549733	DOWN	-2.87904365292011	0.00690829182431416	Staphylococcus aureus infection: FCAR
hsa04670__35	0.00404277835154707	DOWN	-2.87541002609691	0.00698196739205601	Leukocyte transendothelial migration: PTK2
hsa04976__38	0.00410524265048757	DOWN	-2.87056519033263	0.00708333419675496	Bile secretion: ABCC2
hsa04152__63	0.0042652532852727	DOWN	-2.85845310092195	0.00735267057158477	AMPK signaling pathway: PPARG
hsa05169__104	0.00429792619885216	UP	2.85603068303981	0.00740220286676738	Epstein-Barr virus infection: IRF3
hsa04010__15	0.00431434761317068	DOWN	-2.85481947409874	0.00742368055416457	MAPK signaling pathway: NFKB1
hsa04664__23	0.00438060367810815	DOWN	-2.84997463833447	0.00753079076959306	Fc epsilon RI signaling pathway: AKT3
hsa04024__31	0.00439731116287452	DOWN	-2.8487634293934	0.00754570563930705	cAMP signaling pathway: C00165
hsa04024__32	0.00439731116287452	DOWN	-2.8487634293934	0.00754570563930705	cAMP signaling pathway: C01245
hsa03320__20	0.00449877465284868	DOWN	-2.84149617574699	0.00771277150794039	PPAR signaling pathway: SCP2
hsa04068__47	0.00456759045809442	DOWN	-2.83665133998271	0.00781648676754045	FoxO signaling pathway: GADD45G
hsa04068__54	0.00456759045809442	DOWN	-2.83665133998271	0.00781648676754045	FoxO signaling pathway: GADD45G*
hsa04068__53	0.0047438204689355	DOWN	-2.82453925057203	0.00811068122031829	FoxO signaling pathway: SOD2
hsa04510__42	0.00477979642461735	UP	2.82211683268989	0.00815734557843415	Focal adhesion: BIRC2
hsa05152__98	0.00477979642461735	UP	2.82211683268989	0.00815734557843415	Tuberculosis: IL23A
hsa04210__70	0.00490766501337109	DOWN	-2.81363837010241	0.00835281028996765	Apoptosis: CFLAR*
hsa04920__37	0.00490766501337109	UP	2.81363837010241	0.00835281028996765	Adipocytokine signaling pathway: IRS1
hsa05166__89 90	0.00490766501337109	DOWN	-2.81363837010241	0.00835281028996765	HTLV-I infection: CHUK IKBKG
hsa05134__73	0.00492618239921189	DOWN	-2.81242716116134	0.0083767391204698	Legionellosis: CXCL1
hsa04660__30	0.00501972068190481	UP	2.806371116456	0.00852807880768458	T cell receptor signaling pathway: CD40LG
hsa05213__27	0.00505758349145088	UP	2.80394869857386	0.0085846426200869	Endometrial cancer: ELK1
hsa05166__34 35 36	0.00517271894046474	UP	2.79668144492745	0.00877214701185311	HTLV-I infection: MYC TRRAP KAT5
hsa04620__39	0.00519214512223083	DOWN	-2.79547023598638	0.00879715120349119	Toll-like receptor signaling pathway: IL6
hsa04933__57	0.00521163005664911	DOWN	-2.79425902704531	0.00882220979859791	AGE-RAGE signaling pathway in diabetic complications: FIGF
hsa04911__31	0.00523118103386443	DOWN	-2.79304781810424	0.00884733497986612	Insulin secretion: CAMK2A
hsa04550__22	0.00527048189742582	DOWN	-2.7906254002221	0.00890578730689129	Signaling pathways regulating pluripotency of stem cells: SMAD2
hsa04012__24	0.00529023217530795	DOWN	-2.78941419128104	0.00893112871285143	ErbB signaling pathway: CDKN1A
hsa04210__10	0.00531004927906064	DOWN	-2.78820298233997	0.00894850456982506	Apoptosis: BIRC2
hsa04620__77	0.00531004927906064	UP	2.78820298233997	0.00894850456982506	Toll-like receptor signaling pathway: CXCL9
hsa04062__40	0.0053299334056214	DOWN	-2.7869917733989	0.00896593094822078	Chemokine signaling pathway: PRKACA
hsa05150__48	0.0053299334056214	UP	2.7869917733989	0.00896593094822078	Staphylococcus aureus infection: C3AR1
hsa04550__62 63	0.00543036630623351	DOWN	-2.78093572869355	0.00912670687782896	Signaling pathways regulating pluripotency of stem cells: SMAD2 SMAD4
hsa04213__53	0.00549144302682156	DOWN	-2.77730210187035	0.00922110942573522	Longevity regulating pathway - multiple species: SOD1
hsa04151__102	0.0056573570599294	DOWN	-2.7676124303418	0.0094912267103637	PI3K-Akt signaling pathway: C8orf44-SGK3
hsa04010__63	0.00567841116296711	UP	2.76640122140073	0.00951805046852381	MAPK signaling pathway: MAX
hsa04668__116	0.00576333612312077	DOWN	-2.76155638563646	0.0096431955256847	TNF signaling pathway: PGAM5
hsa05168__138	0.00576333612312077	DOWN	-2.76155638563646	0.0096431955256847	Herpes simplex infection: CHUK
hsa04668__38	0.00580622662744421	DOWN	-2.75913396775432	0.00970631657737337	TNF signaling pathway: CEBPB
hsa04620__34	0.00584940469894209	DOWN	-2.75671154987218	0.00976980571494416	Toll-like receptor signaling pathway: IL1B
hsa04919__28	0.00595861898217536	DOWN	-2.75065550516684	0.00994337927842584	Thyroid hormone signaling pathway: RCAN1
hsa05200__207	0.00598068108525776	UP	2.74944429622577	0.00997133962661874	Pathways in cancer: CDK4
hsa04660__40 41	0.0060696673916727	DOWN	-2.7445994604615	0.0101107314086463	T cell receptor signaling pathway: LAT GRAP2
hsa05160__37	0.00618235625300512	DOWN	-2.73854341575615	0.0102893245344523	Hepatitis C: STAT3
hsa05100__15	0.00622826731829478	DOWN	-2.73612099787402	0.0103565613195362	Bacterial invasion of epithelial cells: CTNNA1
hsa04950__18	0.00625122649082743	UP	2.73490978893295	0.0103855478127893	Maturity onset diabetes of the young: SLC2A2
hsa04010__64	0.00632056185916548	UP	2.73127616210974	0.0104914626619893	MAPK signaling pathway: DDIT3
hsa04210__52	0.00634382699635748	DOWN	-2.73006495316867	0.0105207863425911	Apoptosis: PARP2
hsa04115__2	0.00636716917409299	DOWN	-2.7288537442276	0.0105501859595421	p53 signaling pathway: IGFBP3
hsa03320__59	0.0063905886131283	DOWN	-2.72764253528654	0.010579661677593	PPAR signaling pathway: NR1H3
hsa04151__26	0.00641408553472336	DOWN	-2.72643132634547	0.0106092136617475	PI3K-Akt signaling pathway: RBL2
hsa04610__44	0.00646131271315473	DOWN	-2.72400890846333	0.0106779301565679	Complement and coagulation cascades: C3
hsa04022__59	0.00648504341503524	DOWN	-2.72279769952226	0.0107077298566355	cGMP-PKG signaling pathway: NPPB
hsa04064__136	0.00655670665223551	UP	2.71916407269905	0.0108165511848556	NF-kappa B signaling pathway: TNFSF13B*
hsa04360__117	0.00658075218947647	DOWN	-2.71795286375799	0.0108466959333564	Axon guidance: CFL1*
hsa05145__67	0.00660487699757	UP	2.71674165481692	0.010876918386007	Toxoplasmosis: BAD
hsa04921__54	0.00665336533011963	DOWN	-2.71431923693478	0.0109375970737487	Oxytocin signaling pathway: RCAN1
hsa05222__44	0.00665336533011963	UP	2.71431923693478	0.0109375970737487	Small cell lung cancer: RB1
hsa04115__34	0.00680075641922082	DOWN	-2.70705198328837	0.0111701235242272	p53 signaling pathway: ZMAT3
hsa04911__54	0.00687554671430858	UP	2.70341835646516	0.0112732567855025	Insulin secretion: RAB3A
hsa05200__214	0.00687554671430858	UP	2.70341835646516	0.0112732567855025	Pathways in cancer: CSF3R
hsa05168__10	0.00726069639494336	DOWN	-2.68525022234913	0.0118943753496936	Herpes simplex infection: FOS
hsa04014__79	0.00734001050900721	DOWN	-2.68161659552593	0.0120138325317287	Ras signaling pathway: RAC1**
hsa04152__103	0.00742010105973602	UP	2.67798296870272	0.012134351515443	AMPK signaling pathway: ULK1
hsa05150__1 2 3	0.00755532848932609	UP	2.67192692399738	0.0123447497664728	Staphylococcus aureus infection: CFD C3 CFB
hsa04666__20	0.00761003526600893	DOWN	-2.66950450611524	0.0124233329842144	Fc gamma R-mediated phagocytosis: PLA2G4B
hsa04012__40	0.00766509687794004	DOWN	-2.6670820882331	0.0125023585361539	ErbB signaling pathway: ELK1*
hsa05161__207	0.00774835893744765	UP	2.6634484614099	0.0126053389120902	Hepatitis B: CDK2
hsa05161__219	0.00774835893744765	UP	2.6634484614099	0.0126053389120902	Hepatitis B: CDK2*
hsa05200__52	0.00774835893744765	DOWN	-2.6634484614099	0.0126053389120902	Pathways in cancer: CDKN1B
hsa04668__40	0.0078043163026659	DOWN	-2.66102604352776	0.0126744255252457	TNF signaling pathway: JUN
hsa05205__188	0.0078043163026659	DOWN	-2.66102604352776	0.0126744255252457	Proteoglycans in cancer: TNF
hsa04932__56	0.00791731840965471	UP	2.65618120776349	0.0128468404937316	Non-alcoholic fatty liver disease (NAFLD): CASP7
hsa05014__53	0.00794579693864031	UP	2.65496999882242	0.0128819261843875	Amyotrophic lateral sclerosis (ALS): RAB5A
hsa05161__26	0.00797436717313454	UP	2.65375878988135	0.0129059740898534	Hepatitis B: MMP9
hsa05220__22	0.00797436717313454	DOWN	-2.65375878988135	0.0129059740898534	Chronic myeloid leukemia: CDKN1B
hsa04115__37	0.00817694791128541	DOWN	-2.64528032729387	0.013222448472724	p53 signaling pathway: FAS
hsa05200__173	0.00832445574954381	DOWN	-2.63922428258853	0.0134378456644268	Pathways in cancer: CCNA1
hsa05221__16	0.00832445574954381	DOWN	-2.63922428258853	0.0134378456644268	Acute myeloid leukemia: CCNA1
hsa04115__54	0.00859597943719254	DOWN	-2.62832340211891	0.0138642449463389	p53 signaling pathway: PERP
hsa05200__220	0.00868823111352689	DOWN	-2.6246897752957	0.0140010173776304	Pathways in cancer: CSF1R*
hsa04350__12	0.00884395151919342	DOWN	-2.61863373059036	0.0142275555689764	TGF-beta signaling pathway: ACVR2A
hsa05030__73	0.00884395151919342	DOWN	-2.61863373059036	0.0142275555689764	Cocaine addiction: NFKB1
hsa04010__129	0.00887539315328796	UP	2.61742252164929	0.0142415574167618	MAPK signaling pathway: FOS
hsa04910__12	0.00887539315328796	UP	2.61742252164929	0.0142415574167618	Insulin signaling pathway: FASN
hsa05166__132 136	0.00887539315328796	UP	2.61742252164929	0.0142415574167618	HTLV-I infection: CREBBP TP53
hsa04933__19	0.00900216052410227	DOWN	-2.61257768588502	0.0144326447310479	AGE-RAGE signaling pathway in diabetic complications: TGFBR2
hsa05134__6	0.00909829453231985	DOWN	-2.60894405906181	0.0145743354017298	Legionellosis: IL1B
hsa04064__114	0.00916289200403437	DOWN	-2.60652164117967	0.014665310115486	NF-kappa B signaling pathway: BCL2A1*
hsa04933__22	0.00922789854447494	DOWN	-2.60409922329754	0.0147567841404838	AGE-RAGE signaling pathway in diabetic complications: EDN1
hsa04962__22	0.00929331636022268	UP	2.6016768054154	0.0148487597286211	Vasopressin-regulated water reabsorption: ARHGDIA
hsa04210__107	0.00932617738788781	DOWN	-2.60046559647433	0.0148886043431106	Apoptosis: MCL1
hsa05166__32	0.00945867479207739	DOWN	-2.59562076071006	0.0150873089425411	HTLV-I infection: STAT5A
hsa05200__197	0.00952554958003803	DOWN	-2.59319834282792	0.0151682268312639	Pathways in cancer: CCND1**
hsa05200__212	0.00952554958003803	DOWN	-2.59319834282792	0.0151682268312639	Pathways in cancer: CCND1***
hsa04668__128	0.00972871088913953	DOWN	-2.58593108918151	0.0154655226401804	TNF signaling pathway: CHUK*
hsa04976__59	0.00972871088913953	DOWN	-2.58593108918151	0.0154655226401804	Bile secretion: ABCB4
hsa04022__57	0.009762944051352	DOWN	-2.58471988024044	0.0154937262436574	cGMP-PKG signaling pathway: C00144
hsa04390__13	0.009762944051352	UP	2.58471988024044	0.0154937262436574	Hippo signaling pathway: BIRC5
hsa04650__119	0.00979728452785905	DOWN	-2.58350867129937	0.0155351034834153	Natural killer cell mediated cytotoxicity: KLRC4-KLRK1
hsa04014__43	0.00990095270477707	DOWN	-2.57987504447616	0.0156862480036055	Ras signaling pathway: ELK1
hsa05152__97	0.010253607188244	DOWN	-2.56776295506548	0.0162312787756618	Tuberculosis: IL18
hsa03320__55	0.010289480345991	DOWN	-2.56655174612441	0.0162743548570009	PPAR signaling pathway: SCD
hsa05161__194	0.0103977709792643	DOWN	-2.5629181193012	0.0164318012363646	Hepatitis B: TNF*
hsa05160__54	0.0105070745582004	UP	2.559284492478	0.0165766524725933	Hepatitis C: IRF1
hsa05161__45	0.0105070745582004	DOWN	-2.559284492478	0.0165766524725933	Hepatitis B: PCNA
hsa04261__73	0.0105437355680685	UP	2.55807328353693	0.0166205361848999	Adrenergic signaling in cardiomyocytes: KCNE1
hsa05012__57	0.0109545794164468	UP	2.54474998518517	0.0172392418119795	Parkinson's disease: CASP3
hsa05205__238	0.0109545794164468	DOWN	-2.54474998518517	0.0172392418119795	Proteoglycans in cancer: ITGAV*
hsa04933__24	0.0110690689577575	DOWN	-2.54111635836197	0.017404837298432	AGE-RAGE signaling pathway in diabetic complications: THBD
hsa05214__27	0.0113012416745979	UP	2.53384910471556	0.0177402114507681	Glioma: MTOR
hsa05214__48	0.0113012416745979	UP	2.53384910471556	0.0177402114507681	Glioma: MTOR*
hsa04530__5 11 31	0.0115775667345991	DOWN	-2.52537064212808	0.0181588045862369	Tight junction: IGSF5 TJP1 MLLT4
hsa04931__46	0.0121066862090636	DOWN	-2.50962492589418	0.018972863541977	Insulin resistance: PIK3R5*
hsa04910__39	0.0121482618128497	UP	2.50841371695312	0.0190221532886206	Insulin signaling pathway: BAD
hsa04742__18	0.0122317927748784	UP	2.50599129907098	0.0191210803860204	Taste transduction: PDE1A
hsa05140__43	0.0122317927748784	DOWN	-2.50599129907098	0.0191210803860204	Leishmaniasis: MAPK14
hsa04150__56	0.012273748780514	UP	2.50478009012991	0.0191707181700631	mTOR signaling pathway: EIF4B
hsa04970__18	0.0123580434640938	UP	2.50235767224777	0.0192863485623191	Salivary secretion: VAMP2
hsa04115__58	0.0126571271930714	UP	2.49387920966029	0.0197367153491961	p53 signaling pathway: CASP3
hsa04024__21	0.0127437483310351	UP	2.49145679177815	0.0198553093814386	cAMP signaling pathway: AKT3
hsa04921__59	0.0130067678371429	DOWN	-2.48418953813174	0.0202483154647817	Oxytocin signaling pathway: CCND1
hsa04917__68	0.0133649246159097	DOWN	-2.47449986660319	0.0207886534381575	Prolactin signaling pathway: CCND1
hsa05133__94	0.0137782459155461	DOWN	-2.46359898613358	0.0214138329820604	Pertussis: IL12A
hsa05221__21	0.0138716136282317	DOWN	-2.46117656825144	0.0215411256259896	Acute myeloid leukemia: PIM1
hsa04530__11 33	0.0142506941820775	DOWN	-2.45148689672289	0.0221115230124885	Tight junction: TJP1 CGN
hsa04350__32	0.0146388849056688	DOWN	-2.44179722519434	0.022695102918937	TGF-beta signaling pathway: RPS6KB1
hsa04976__41	0.0148862109575839	UP	2.435741180489	0.0230595139235781	Bile secretion: CYP7A1
hsa04914__15	0.0149861676867669	UP	2.43331876260686	0.0231952298875083	Progesterone-mediated oocyte maturation: ANAPC10
hsa05219__21	0.0151372114144239	UP	2.42968513578365	0.0234097285989321	Bladder cancer: RB1
hsa04350__11	0.0151878564091341	DOWN	-2.42847392684259	0.0234687353558906	TGF-beta signaling pathway: SMAD4*
hsa04115__21	0.0153919315228908	DOWN	-2.42362909107831	0.0237645351943401	p53 signaling pathway: DDB2
hsa04064__95	0.0154433259123351	DOWN	-2.42241788213724	0.0238243098434136	NF-kappa B signaling pathway: BCL2L1**
hsa04520__44 52 45	0.0155465679914938	DOWN	-2.41999546425511	0.0239639058703993	Adherens junction: ACTB ACTN4 CTNNA1
hsa04520__43	0.0156504169253543	DOWN	-2.41757304637297	0.0240844663413111	Adherens junction: ACTB
hsa04650__36	0.0156504169253543	UP	2.41757304637297	0.0240844663413111	Natural killer cell mediated cytotoxicity: CASP3
hsa05014__13	0.0165034117950289	UP	2.39819370331587	0.0253763590530764	Amyotrophic lateral sclerosis (ALS): CASP3
hsa05152__94	0.0165580547701293	DOWN	-2.3969824943748	0.025439562480027	Tuberculosis: CAMP
hsa04062__25	0.0168892614588463	DOWN	-2.38971524072839	0.025927224085925	Chemokine signaling pathway: ROCK1
hsa04068__57	0.0169450242847351	DOWN	-2.38850403178732	0.0259915923518508	FoxO signaling pathway: IL7R
hsa04066__61	0.0171132833839464	DOWN	-2.38487040496412	0.0262282703739277	HIF-1 signaling pathway: HMOX1
hsa04064__135	0.0171696945781047	UP	2.38365919602305	0.0262932812650845	NF-kappa B signaling pathway: CCL19
hsa04115__49	0.0172262688313613	UP	2.38244798708198	0.0263584357769771	p53 signaling pathway: MDM2*
hsa04360__96	0.0172830065318102	UP	2.38123677814091	0.0264237341523771	Axon guidance: GSK3B
hsa04650__110 111	0.0176847796908616	UP	2.37275831555343	0.0270160171049829	Natural killer cell mediated cytotoxicity: ITGAL ITGB2
hsa04360__35	0.0186339872740192	DOWN	-2.35337897249633	0.0284198555908134	Axon guidance: ROCK1*
hsa05210__22	0.0186339872740192	UP	2.35337897249633	0.0284198555908134	Colorectal cancer: MYC
hsa04064__55	0.0187557176913942	DOWN	-2.35095655461419	0.0285823143082966	NF-kappa B signaling pathway: CXCL12
hsa04340__17	0.0188781431612511	UP	2.34853413673206	0.0287455680713053	Hedgehog signaling pathway: SMO
hsa04062__38	0.0190012669296731	DOWN	-2.34611171884992	0.0289096198873325	Chemokine signaling pathway: NCF1
hsa05134__9	0.0191872690182622	UP	2.34247809202671	0.0291689955382804	Legionellosis: CASP7
hsa03320__42	0.0192496223980292	DOWN	-2.34126688308565	0.0292401297379926	PPAR signaling pathway: ACOX1
hsa04360__58	0.019374860641617	DOWN	-2.33884446520351	0.029406593817123	Axon guidance: PLXNC1
hsa04010__54	0.0194377463272566	DOWN	-2.33763325626244	0.0294782286916184	MAPK signaling pathway: NR4A1
hsa05134__69	0.0196910757800484	DOWN	-2.33278842049817	0.0298383317667023	Legionellosis: IL1B*
hsa04620__46	0.0198188183236198	DOWN	-2.33036600261603	0.0300077031668668	Toll-like receptor signaling pathway: TNF
hsa04668__120	0.0201413449821466	UP	2.32430995791068	0.0304714872958562	TNF signaling pathway: DNM1L
hsa04014__65	0.0203370516101733	DOWN	-2.32067633108748	0.0307428157486048	Ras signaling pathway: MLLT4*
hsa05134__72	0.0209341581336741	DOWN	-2.30977545061786	0.0316200025186283	Legionellosis: IL12A
hsa05217__3	0.0219633146434341	DOWN	-2.29160731650183	0.0331478459558335	Basal cell carcinoma: GLI1
hsa04210__86	0.0220334639559834	DOWN	-2.29039610756076	0.0332270295130761	Apoptosis: BCL2L11
hsa05152__88 89	0.0221038080916834	UP	2.28918489861969	0.0333063796345414	Tuberculosis: ITGAX ITGB2
hsa04742__47	0.0222450825835447	DOWN	-2.28676248073756	0.0334655806040677	Taste transduction: GABRA1
hsa05213__12	0.0222450825835447	UP	2.28676248073756	0.0334655806040677	Endometrial cancer: BAD
hsa04064__134	0.0223871416274451	DOWN	-2.28434006285542	0.0336523512943754	NF-kappa B signaling pathway: CCL21
hsa04933__25	0.0225299887420617	DOWN	-2.28191764497328	0.03384000707141	AGE-RAGE signaling pathway in diabetic complications: IL1A
hsa04210__57	0.0228180613093738	UP	2.27707280920901	0.0342453172526465	Apoptosis: BAK1
hsa05161__227	0.0232561692464462	UP	2.2698055555626	0.0348749736744393	Hepatitis B: MYD88*
hsa05031__10	0.0233298928498131	DOWN	-2.26859434662153	0.034929775828525	Amphetamine addiction: CACNA1C
hsa05031__53	0.0233298928498131	DOWN	-2.26859434662153	0.034929775828525	Amphetamine addiction: CACNA1C*
hsa04660__35	0.0236268197348676	DOWN	-2.26374951085725	0.0352899795562926	T cell receptor signaling pathway: NFATC1
hsa04724__44	0.0236268197348676	DOWN	-2.26374951085725	0.0352899795562926	Glutamatergic synapse: PRKACA*
hsa04920__26	0.0236268197348676	UP	2.26374951085725	0.0352899795562926	Adipocytokine signaling pathway: NPY
hsa04623__8	0.0238516616043882	UP	2.26011588403405	0.0355975156113149	Cytosolic DNA-sensing pathway: TBK1
hsa04020__7	0.0243069183987524	DOWN	-2.25284863038764	0.0362481743422664	Calcium signaling pathway: ADCY1
hsa04620__76	0.0244603352855772	DOWN	-2.2504262125055	0.0364480333081678	Toll-like receptor signaling pathway: CCL3L3
hsa04020__8	0.0245373579016518	DOWN	-2.24921500356443	0.0364760249186739	Calcium signaling pathway: PDE1A
hsa04151__25	0.0245373579016518	DOWN	-2.24921500356443	0.0364760249186739	PI3K-Akt signaling pathway: CDKN1B
hsa04910__24	0.0245373579016518	UP	2.24921500356443	0.0364760249186739	Insulin signaling pathway: ACACA
hsa04917__37	0.0249256310732475	DOWN	-2.24315895885909	0.0369946767666919	Prolactin signaling pathway: TNFSF11
hsa05134__70	0.0249256310732475	DOWN	-2.24315895885909	0.0369946767666919	Legionellosis: IL6
hsa05200__215	0.0250824236508183	UP	2.24073654097695	0.0371980063456097	Pathways in cancer: CSF1R
hsa05016__60	0.0253985719754486	UP	2.23589170521267	0.0376074994025752	Huntington's disease: CASP3*
hsa05134__35	0.0253985719754486	UP	2.23589170521267	0.0376074994025752	Legionellosis: CASP3
hsa05223__9	0.0254781457597709	UP	2.23468049627161	0.0376956188052043	Non-small cell lung cancer: BAD
hsa05212__27	0.0257986016964085	DOWN	-2.22983566050733	0.0381397109264765	Pancreatic cancer: BCL2L1*
hsa05016__12	0.0258792582193899	DOWN	-2.22862445156626	0.0382288727942088	Huntington's disease: REST
hsa04530__6 11 45	0.0260412255953199	DOWN	-2.22620203368413	0.0384379127208218	Tight junction: CLDN24 TJP1 TJP2
hsa04390__5	0.0261225373888896	DOWN	-2.22499082474306	0.0385276669966434	Hippo signaling pathway: SAV1
hsa04071__48	0.0263677133005707	UP	2.22135719791985	0.0388587712092333	Sphingolipid signaling pathway: SMPD1
hsa04068__58	0.0267809686011883	DOWN	-2.21530115321451	0.0394368652050414	FoxO signaling pathway: KLF2
hsa04024__12	0.0269477984768778	UP	2.21287873533237	0.0396514591527435	cAMP signaling pathway: SLC9A1
hsa04261__23	0.0272841514030984	UP	2.2080338995681	0.0401149612569812	Adrenergic signaling in cardiomyocytes: SLC9A1
hsa04921__43	0.027368803506343	UP	2.20682269062703	0.0402079607415312	Oxytocin signaling pathway: CACNG3
hsa04115__56	0.0274536821185545	UP	2.20561148168596	0.0403011474224718	p53 signaling pathway: SESN3
hsa04622__6	0.0277096818244109	DOWN	-2.20197785486275	0.0406134884150297	RIG-I-like receptor signaling pathway: NFKB1
hsa05133__96	0.0277096818244109	DOWN	-2.20197785486275	0.0406134884150297	Pertussis: IL1B
hsa04742__48	0.0277954712910087	UP	2.20076664592169	0.0406757714609076	Taste transduction: GABBR1
hsa04933__78	0.0277954712910087	DOWN	-2.20076664592169	0.0406757714609076	AGE-RAGE signaling pathway in diabetic complications: TGFB1
hsa04210__71	0.0279677374725012	DOWN	-2.19834422803955	0.0408642136165083	Apoptosis: GADD45G
hsa04921__48	0.0279677374725012	UP	2.19834422803955	0.0408642136165083	Oxytocin signaling pathway: PRKAG2
hsa04726__10	0.0281409232169946	DOWN	-2.19592181015741	0.041085310586428	Serotonergic synapse: PRKACA
hsa04066__54	0.028490068952707	DOWN	-2.19107697439314	0.0415627636351991	HIF-1 signaling pathway: SERPINE1
hsa05160__85	0.0285779361988297	UP	2.18986576545207	0.0416586052114826	Hepatitis C: BAD
hsa04924__49	0.028666036747419	DOWN	-2.188654556511	0.0417546380220158	Renin secretion: PDE1A
hsa04068__14	0.0293792989377906	DOWN	-2.17896488498245	0.0427604203749872	FoxO signaling pathway: G6PC
hsa03320__36	0.0302923027561164	DOWN	-2.16685279557176	0.0440551369030516	PPAR signaling pathway: SLC27A4
hsa05168__39 40	0.0304778001053537	DOWN	-2.16443037768963	0.0442906313982673	Herpes simplex infection: POU2F3 HCFC2
hsa04931__35	0.0306642723260652	UP	2.16200795980749	0.0445271775121148	Insulin resistance: C00369
hsa04068__88	0.03085172344165	DOWN	-2.15958554192535	0.0447647786462241	FoxO signaling pathway: FBXO32
hsa04668__102	0.0309458173449583	UP	2.15837433298428	0.0448666595610931	TNF signaling pathway: AKT3
hsa04211__51	0.0317074756452358	UP	2.14868466145573	0.0459355024960663	Longevity regulating pathway - mammal: NFKB1
hsa05133__30	0.0331789681891739	DOWN	-2.1305165273397	0.0480302628871015	Pertussis: NOS2
hsa04150__33	0.0337837226704427	UP	2.12324927369329	0.0488680638165987	mTOR signaling pathway: RPS6
hsa04726__39	0.0338854260315762	UP	2.12203806475222	0.0489774734717935	Serotonergic synapse: CACNA1C
hsa04152__49	0.0340896182648012	UP	2.11961564687009	0.0492347369097322	AMPK signaling pathway: GYS1
hsa05169__29	0.0347085167974775	DOWN	-2.11234839322368	0.0500900945180186	Epstein-Barr virus infection: FCER2
hsa05161__188	0.0358681050444696	DOWN	-2.09902509487192	0.0517238444962075	Hepatitis B: IFNB1
hsa04915__58	0.036082450638015	UP	2.09660267698978	0.0519930404515569	Estrogen signaling pathway: CREB3***
hsa04151__97	0.0362978873127993	UP	2.09418025910765	0.0522633948358237	PI3K-Akt signaling pathway: MCL1
hsa05200__224	0.0371706306231563	UP	2.0844905875791	0.0534381139563204	Pathways in cancer: MYC***
hsa05221__12	0.0371706306231563	UP	2.0844905875791	0.0534381139563204	Acute myeloid leukemia: MYC
hsa04750__59	0.0372809695333991	DOWN	-2.08327937863803	0.0535557658664044	Inflammatory mediator regulation of TRP channels: TRPV2
hsa04961__20	0.0373911571014904	DOWN	-2.08206816969696	0.0536730207744083	Endocrine and other factor-regulated calcium reabsorption: CALB1*
hsa04910__57	0.0378368552230153	UP	2.07722333393269	0.0542299397132309	Insulin signaling pathway: GCK
hsa05200__185	0.0378368552230153	DOWN	-2.07722333393269	0.0542299397132309	Pathways in cancer: HHIP
hsa04350__10	0.0383997759031011	DOWN	-2.07116728922734	0.0549948010075663	TGF-beta signaling pathway: SMAD4
hsa04064__97	0.0391998134126161	DOWN	-2.06268882663986	0.056055136531435	NF-kappa B signaling pathway: PLCG2
hsa05222__19	0.0391998134126161	UP	2.06268882663986	0.056055136531435	Small cell lung cancer: CASP9
hsa05010__12	0.0393152519363837	UP	2.06147761769879	0.0561774588505437	Alzheimer's disease: CASP3
hsa04726__16	0.0395469950689198	DOWN	-2.05905519981666	0.0564227818788917	Serotonergic synapse: ITPR1
hsa04726__46	0.0395469950689198	DOWN	-2.05905519981666	0.0564227818788917	Serotonergic synapse: ITPR1*
hsa05160__55	0.0398967832511312	UP	2.05542157299345	0.0568786462282819	Hepatitis C: MAPK14
hsa04920__31	0.0401314308067189	UP	2.05299915511131	0.0571264837013824	Adipocytokine signaling pathway: AGRP
hsa05216__11	0.0401314308067189	UP	2.05299915511131	0.0571264837013824	Thyroid cancer: MYC
hsa04550__101	0.0402491928752153	UP	2.05178794617024	0.0572507444455182	Signaling pathways regulating pluripotency of stem cells: ESRRB
hsa04976__37	0.0403672399470507	DOWN	-2.05057673722918	0.0573318660320086	Bile secretion: ABCB11
hsa04912__14	0.0403672478767149	UP	2.05057673722918	0.0573318660320086	GnRH signaling pathway: ATF4
hsa05152__51	0.0413223001912402	UP	2.04088706570063	0.0586439592593205	Tuberculosis: CASP3
hsa04022__9	0.0414430166288932	UP	2.03967585675956	0.0587708892420305	cGMP-PKG signaling pathway: ITPR1
hsa05321__19	0.041806959223002	DOWN	-2.03604222993635	0.059242289879352	Inflammatory bowel disease (IBD): TNF
hsa04152__89	0.0426666914666544	DOWN	-2.02756376734887	0.0604150062289704	AMPK signaling pathway: CFTR
hsa04727__26	0.0432898986052098	DOWN	-2.02150772264353	0.061113237775499	GABAergic synapse: KCNJ6
hsa05032__81	0.0432898986052098	DOWN	-2.02150772264353	0.061113237775499	Morphine addiction: KCNJ6
hsa05032__91	0.0432898986052098	DOWN	-2.02150772264353	0.061113237775499	Morphine addiction: KCNJ6**
hsa05032__85	0.0432898986052098	DOWN	-2.02150772264353	0.061113237775499	Morphine addiction: KCNJ6*
hsa04914__23	0.0436675018998032	DOWN	-2.01787409582032	0.061600027079377	Progesterone-mediated oocyte maturation: PRKACA
hsa05164__65 66	0.043793986239016	UP	2.01666288687925	0.0617321081343669	Influenza A: DNAJC3 HSPA1A
hsa04750__44	0.0439204366223607	DOWN	-2.01545167793819	0.0618176033059294	Inflammatory mediator regulation of TRP channels: TRPA1
hsa04750__63	0.0439204366223607	DOWN	-2.01545167793819	0.0618176033059294	Inflammatory mediator regulation of TRP channels: TRPA1*
hsa04910__32	0.0446880671299914	DOWN	-2.00818442429177	0.0628509566895612	Insulin signaling pathway: EIF4E
hsa04932__55	0.0465224713291741	UP	1.99122749911681	0.0653819922419731	Non-alcoholic fatty liver disease (NAFLD): CASP3
hsa05200__190	0.046655891146133	UP	1.99001629017574	0.0655204928726337	Pathways in cancer: MYC*
hsa04623__17	0.0471927949639203	UP	1.98517145441147	0.066224990095001	Cytosolic DNA-sensing pathway: NFKB1
hsa04340__14	0.0481448806658205	UP	1.97669299182399	0.0674602764884987	Hedgehog signaling pathway: PTCH1
hsa04914__42	0.0481448806658205	DOWN	-1.97669299182399	0.0674602764884987	Progesterone-mediated oocyte maturation: ARAF
hsa04660__56	0.0482822013501678	DOWN	-1.97548178288292	0.0676022774493035	T cell receptor signaling pathway: CD3E
hsa03320__37	0.0488347785663575	DOWN	-1.97063694711865	0.068274217951031	PPAR signaling pathway: HMGCS2
hsa05169__79	0.0488347785663575	DOWN	-1.97063694711865	0.068274217951031	Epstein-Barr virus infection: ATF2
hsa04917__38	0.0492526870898003	DOWN	-1.96700332029544	0.0688072855328882	Prolactin signaling pathway: IRF1
hsa04650__16	0.0502394883268586	DOWN	-1.95852485770796	0.070133728503839	Natural killer cell mediated cytotoxicity: PRKCA
hsa05160__66	0.0503818035851019	UP	1.95731364876689	0.0702801848080226	Hepatitis C: GSK3B
hsa04933__26	0.0510984569810178	DOWN	-1.95125760406155	0.0712270034624128	AGE-RAGE signaling pathway in diabetic complications: IL6
hsa05160__8	0.0512428072272286	DOWN	-1.95004639512048	0.0713752667012324	Hepatitis C: NFKB1
hsa04914__29	0.0513874248258759	UP	1.94883518617941	0.0715236824057933	Progesterone-mediated oocyte maturation: CDK2
hsa05150__40	0.051969688936422	UP	1.94399035041514	0.07228056662586	Staphylococcus aureus infection: FCGR1A
hsa05205__113	0.0521160955368377	UP	1.94277914147407	0.0724305795219807	Proteoglycans in cancer: TP53
hsa04950__16	0.0522628469462718	UP	1.941567932533	0.0725808495284883	Maturity onset diabetes of the young: PAX4
hsa05212__12	0.053150629811102	UP	1.93430067888659	0.0737592565842397	Pancreatic cancer: CASP9
hsa03320__33	0.0534493429813072	DOWN	-1.93187826100445	0.0741190520013846	PPAR signaling pathway: CYP7A1
hsa04072__27	0.0535992245508342	DOWN	-1.93066705206338	0.0742173492490917	Phospholipase D signaling pathway: C01245
hsa04660__44	0.0535992245508342	DOWN	-1.93066705206338	0.0742173492490917	T cell receptor signaling pathway: PAK4
hsa04152__60	0.054202264722858	UP	1.92582221629911	0.0749970952976805	AMPK signaling pathway: EEF2
hsa04742__8	0.0545058058026065	UP	1.92339979841697	0.0753063154580109	Taste transduction: PLCB2
hsa05161__214	0.0545059015555587	UP	1.92339979841697	0.0753063154580109	Hepatitis B: CDKN1B
hsa05134__68	0.054964016275218	DOWN	-1.91976617159376	0.0758834581786441	Legionellosis: TNF
hsa04666__51	0.0554253368254066	DOWN	-1.91613254477056	0.0764641761343164	Fc gamma R-mediated phagocytosis: NCF1
hsa04666__30 44	0.0569864347159512	DOWN	-1.90402045535987	0.0785601693552988	Fc gamma R-mediated phagocytosis: C04637 GSN
hsa04924__30	0.0576210339767125	UP	1.8991756195956	0.0793767762773041	Renin secretion: PDE3A
hsa04810__35 81 80	0.0577805985389136	DOWN	-1.89796441065453	0.079480047331346	Regulation of actin cytoskeleton: MYL12B MYH9 ACTB
hsa04917__56	0.0577805985389136	DOWN	-1.89796441065453	0.079480047331346	Prolactin signaling pathway: LHCGR
hsa05010__59	0.05923327305082	UP	1.88706353018491	0.0814186686631242	Alzheimer's disease: LRP1
hsa05152__126	0.059888567627076	DOWN	-1.88221869442064	0.0822592241018098	Tuberculosis: NOS2
hsa05321__123	0.060053327399274	DOWN	-1.88100748547957	0.0824252755173381	Inflammatory bowel disease (IBD): IL5*
hsa04610__7	0.0605498632381467	DOWN	-1.87737385865636	0.0830461262952391	Complement and coagulation cascades: C00290
hsa04664__25	0.0612171991759568	DOWN	-1.87252902289209	0.083900158462161	Fc epsilon RI signaling pathway: MAPK14
hsa04913__12	0.0617216887721021	DOWN	-1.86889539606888	0.0845299221594605	Ovarian steroidogenesis: HSD3B1
hsa04912__46	0.0622296148280884	DOWN	-1.86526176924568	0.0851634714216883	GnRH signaling pathway: JUN
hsa04950__30	0.0625701495675959	UP	1.86283935136354	0.0855671841612173	Maturity onset diabetes of the young: PAX6*
hsa04310__36	0.063083840081684	UP	1.85920572454033	0.0861442845301484	Wnt signaling pathway: MYC
hsa04912__15	0.063083840081684	DOWN	-1.85920572454033	0.0861442845301484	GnRH signaling pathway: CAMK2A
hsa04151__36	0.0646458640475708	DOWN	-1.84830484407072	0.0882132015580142	PI3K-Akt signaling pathway: PCK1
hsa04210__83	0.0653502710734961	DOWN	-1.84346000830644	0.0891096947366467	Apoptosis: TP53*
hsa03320__45	0.06588271990958	DOWN	-1.83982638148324	0.0897705806454683	PPAR signaling pathway: PDPK1
hsa04740__37	0.0669583452701191	UP	1.83255912783682	0.0911700947554738	Olfactory transduction: CNGB1*
hsa04540__12	0.0673200404960509	DOWN	-1.83013670995469	0.0915962028183053	Gap junction: C00025
hsa04961__26	0.0675015554434548	UP	1.82892550101362	0.0917767168438868	Endocrine and other factor-regulated calcium reabsorption: TRPV5*
hsa04115__23	0.0678657060681455	DOWN	-1.82650308313148	0.0922051060752316	p53 signaling pathway: PTEN
hsa04115__17	0.0684149602606143	DOWN	-1.82286945630828	0.0928841837642299	p53 signaling pathway: TP73
hsa05152__78	0.0693385009440848	DOWN	-1.81681341160293	0.0940700673458017	Tuberculosis: IL1A
hsa03320__30	0.0702722557228879	UP	1.81075736689759	0.0952680869432225	PPAR signaling pathway: LPL
hsa04710__5	0.0704602392621997	UP	1.80954615795652	0.0954540660228357	Circadian rhythm: RORA
hsa04110__48	0.0708374439412994	UP	1.80712374007438	0.0958959345574219	Cell cycle: RB1*
hsa04933__29	0.0714063543746672	UP	1.80349011325118	0.0965965009863208	AGE-RAGE signaling pathway in diabetic complications: ICAM1
hsa05223__8	0.0715968212744344	UP	1.80227890431011	0.0967844799817714	Non-small cell lung cancer: CASP9
hsa05211__41	0.07197900397587	DOWN	-1.79985648642797	0.0972311635303089	Renal cell carcinoma: PDGFB*
hsa04742__4	0.0725554097101473	DOWN	-1.79622285960477	0.097939378480867	Taste transduction: TRPM5
hsa04151__109	0.0727483825851153	DOWN	-1.7950116506637	0.0981293688998074	PI3K-Akt signaling pathway: RXRA
hsa03320__28	0.0729417753235037	DOWN	-1.79380044172263	0.0982491726400455	PPAR signaling pathway: ACSL1
hsa04662__10	0.0729417753235037	UP	1.79380044172263	0.0982491726400455	B cell receptor signaling pathway: GSK3B
hsa05205__215 216	0.0733298229074518	DOWN	-1.79137802384049	0.0987011011770071	Proteoglycans in cancer: EIF4B RPS6
hsa05014__2	0.0745041078443518	UP	1.78411077019408	0.100209891653212	Amyotrophic lateral sclerosis (ALS): SLC1A2
hsa04530__11 20 16	0.075494374951203	UP	1.77805472548874	0.101396662282566	Tight junction: TJP1 ACTB CTTN
hsa04810__23	0.075494374951203	UP	1.77805472548874	0.101396662282566	Regulation of actin cytoskeleton: GSN
hsa04724__65	0.0756935147083034	DOWN	-1.77684351654767	0.101519260999309	Glutamatergic synapse: GRM3
hsa04932__138	0.0756937118999638	UP	1.77684351654767	0.101519260999309	Non-alcoholic fatty liver disease (NAFLD): CEBPA
hsa04920__9	0.0758934781628816	UP	1.7756323076066	0.101714583072792	Adipocytokine signaling pathway: G6PC
hsa04664__46	0.077507139306204	DOWN	-1.76594263607805	0.103803217930404	Fc epsilon RI signaling pathway: PLA2G4B
hsa04015__3	0.0781194222985711	DOWN	-1.76230900925484	0.104548714030638	Rap1 signaling pathway: MAPK1
hsa04151__32	0.0789419190448152	UP	1.75746417349057	0.105574281768831	PI3K-Akt signaling pathway: BCL2L1
hsa04152__38	0.0795634032913137	UP	1.75383054666736	0.106329754469686	AMPK signaling pathway: PFKL
hsa05212__8	0.0799799316460213	DOWN	-1.75140812878523	0.106734582075905	Pancreatic cancer: NFKB1
hsa05222__40	0.0799799316460213	DOWN	-1.75140812878523	0.106734582075905	Small cell lung cancer: TRAF1
hsa04662__32 51	0.0801888593773396	DOWN	-1.75019691984416	0.106937449801292	B cell receptor signaling pathway: BLNK GRB2
hsa05169__83	0.0806080451097652	UP	1.74777450196202	0.107420224653368	Epstein-Barr virus infection: GSK3B
hsa04014__55	0.080818304375734	DOWN	-1.74656329302095	0.107624092077962	Ras signaling pathway: MLLT4
hsa04151__98	0.0810290087515067	UP	1.74535208407988	0.10782826306238	PI3K-Akt signaling pathway: BCL2L1*
hsa04015__27	0.0812401588695986	UP	1.74414087513881	0.108032737803238	Rap1 signaling pathway: RALA
hsa05200__218	0.0820892294164129	UP	1.73929603937454	0.109084626643168	Pathways in cancer: CSF3R*
hsa05200__186	0.0823026177347421	DOWN	-1.73808483043347	0.109290896624438	Pathways in cancer: PTCH1*
hsa04151__63	0.0829454824479009	UP	1.73445120361027	0.110066780734185	PI3K-Akt signaling pathway: CASP9
hsa04621__42	0.0831606727139061	UP	1.7332399946692	0.1102744559135	NOD-like receptor signaling pathway: MAPK8
hsa05161__44	0.0844613298944201	UP	1.72597274102279	0.111920196665455	Hepatitis B: CXCL8
hsa05145__35	0.0846796979268372	UP	1.72476153208172	0.112130480905234	Toxoplasmosis: CASP3
hsa05145__33	0.0853375435380199	DOWN	-1.72112790525851	0.112842536458789	Toxoplasmosis: STAT3
hsa05169__125	0.0853375435380199	DOWN	-1.72112790525851	0.112842536458789	Epstein-Barr virus infection: STAT3
hsa05205__183	0.0855577413550275	UP	1.71991669631744	0.113054146277143	Proteoglycans in cancer: VEGFA*
hsa04933__65	0.086221091501445	DOWN	-1.71628306949424	0.113850619066209	AGE-RAGE signaling pathway in diabetic complications: COL1A1
hsa04261__15 17	0.0868885899726118	DOWN	-1.71264944267103	0.114651447021445	Adrenergic signaling in cardiomyocytes: ACTC1 MYH6
hsa05133__27	0.0871120142640681	DOWN	-1.71143823372996	0.11486559635241	Pertussis: IRF3
hsa05160__70	0.0902889046339329	DOWN	-1.694481308555	0.118971144324797	Hepatitis C: CDKN1A
hsa05031__101	0.090519347096462	DOWN	-1.69327009961393	0.119191207564297	Amphetamine addiction: FOS*
hsa04024__24	0.0937954863372968	DOWN	-1.67631317443897	0.123332203518391	cAMP signaling pathway: PLN
hsa04750__90	0.0937954863372968	UP	1.67631317443897	0.123332203518391	Inflammatory mediator regulation of TRP channels: C01245**
hsa05160__12 13 14	0.0954688569967344	DOWN	-1.66783471185149	0.12544474286494	Hepatitis C: IKBKG CHUK IKBKB
hsa04068__50	0.0969221267650404	DOWN	-1.66056745820508	0.127265322286171	FoxO signaling pathway: TNFSF10
hsa04670__86	0.0974104627535551	UP	1.65814504032294	0.127728024782924	Leukocyte transendothelial migration: ACTB
hsa04726__38	0.0974104627535551	DOWN	-1.65814504032294	0.127728024782924	Serotonergic synapse: PLA2G4B
hsa04921__33	0.0976553672092934	UP	1.65693383138187	0.127959857033656	Oxytocin signaling pathway: C00942
hsa04015__92	0.0979005905102821	UP	1.65572262244081	0.128191783671652	Rap1 signaling pathway: C00076*
hsa04923__26 27	0.0991349430553809	DOWN	-1.64966657773546	0.129627651626942	Regulation of lipolysis in adipocytes: PNPLA2 ABHD5
hsa05200__210	0.0991351438999019	DOWN	-1.64966657773546	0.129627651626942	Pathways in cancer: MMP1
hsa05168__29	0.100131564722382	DOWN	-1.64482174197119	0.130839506337522	Herpes simplex infection: IKBKG
hsa05213__13	0.100632761057337	UP	1.64239932408905	0.131403028510587	Endometrial cancer: CASP9
hsa04620__48	0.101388302023152	DOWN	-1.63876569726584	0.132297652431599	Toll-like receptor signaling pathway: CD80
hsa04924__58	0.101641150565766	DOWN	-1.63755448832478	0.132443635168568	Renin secretion: PPP3CA
hsa05031__59	0.101641150565766	DOWN	-1.63755448832478	0.132443635168568	Amphetamine addiction: PPP3CA
hsa04380__48	0.102402709588246	DOWN	-1.63392086150157	0.133343514425721	Osteoclast differentiation: NFATC1
hsa04664__47	0.102657569138229	DOWN	-1.6327096525605	0.133582806378624	Fc epsilon RI signaling pathway: MAPK8
hsa04710__11	0.103168801789073	DOWN	-1.63028723467836	0.134155140873127	Circadian rhythm: CRY1
hsa04066__26	0.103939443976947	DOWN	-1.62665360785516	0.135063772636711	HIF-1 signaling pathway: C01245
hsa04923__52 53	0.106016861795958	DOWN	-1.61696393632661	0.137668060341814	Regulation of lipolysis in adipocytes: PNPLA2 ABHD5*
hsa04922__70	0.106541327675054	UP	1.61454151844447	0.138253559876676	Glucagon signaling pathway: PFKFB1
hsa04068__42	0.106804330734819	DOWN	-1.6133303095034	0.1384036810005	FoxO signaling pathway: CDKN2D
hsa04932__95	0.106804330734819	DOWN	-1.6133303095034	0.1384036810005	Non-alcoholic fatty liver disease (NAFLD): IL1A
hsa04152__27	0.107067848032728	DOWN	-1.61211910056234	0.138554054031334	AMPK signaling pathway: ADIPOR1
hsa05152__82	0.107067848032728	DOWN	-1.61211910056234	0.138554054031334	Tuberculosis: IL6
hsa04612__17 28	0.110000654588875	UP	1.59879580221058	0.142251362678937	Antigen processing and presentation: CD4 HLA-DMA
hsa04725__18	0.112996578544631	DOWN	-1.58547250385883	0.14592479112396	Cholinergic synapse: ITPR1
hsa05162__62	0.112996578544631	DOWN	-1.58547250385883	0.14592479112396	Measles: IL12A
hsa05216__12	0.11403183620859	DOWN	-1.57941645915348	0.147160590821388	Thyroid cancer: CDH1
hsa04340__26	0.114657613827866	UP	1.57820525021241	0.147866613852135	Hedgehog signaling pathway: PTCH1**
hsa05205__220	0.114936311588605	DOWN	-1.57699404127135	0.148124368638538	Proteoglycans in cancer: FAS
hsa05162__105	0.11577560311574	UP	1.57336041444814	0.149103741092855	Measles: GSK3B
hsa03320__58	0.116056435063505	DOWN	-1.57214920550707	0.149363042112551	PPAR signaling pathway: CYP8B1
hsa05145__4 5	0.117468632866877	DOWN	-1.56609316080173	0.151077043912978	Toxoplasmosis: MAP3K7 TAB1
hsa04913__21	0.118608073070182	DOWN	-1.56124832503745	0.152229897062071	Ovarian steroidogenesis: CYP17A1
hsa04913__22	0.118608073070182	DOWN	-1.56124832503745	0.152229897062071	Ovarian steroidogenesis: CYP17A1*
hsa04933__23	0.118608073070182	DOWN	-1.56124832503745	0.152229897062071	AGE-RAGE signaling pathway in diabetic complications: F3
hsa04917__31	0.119181033767289	UP	1.55882590715532	0.152860861739751	Prolactin signaling pathway: GALT
hsa05132__48	0.119756161282505	DOWN	-1.55640348927318	0.153493742871642	Salmonella infection: KLC3
hsa04350__44 45	0.120333460422624	DOWN	-1.55398107139104	0.154128542695372	TGF-beta signaling pathway: TGFBR2 TGFBR1
hsa03320__8	0.120622925852129	DOWN	-1.55276986244997	0.15418399841915	PPAR signaling pathway: GK
hsa04115__16	0.120622925852129	UP	1.55276986244997	0.15418399841915	p53 signaling pathway: PPM1D
hsa04917__57	0.120622925852129	DOWN	-1.55276986244997	0.15418399841915	Prolactin signaling pathway: ESR1
hsa04742__55	0.121200571003353	UP	1.55034744456784	0.154715598090859	Taste transduction: P2RX3
hsa04668__153	0.121203491426154	UP	1.55034744456784	0.154715598090859	TNF signaling pathway: MAPK14*
hsa04014__61	0.122664469107158	UP	1.54429139986249	0.156474227734115	Ras signaling pathway: RAP1A
hsa04010__78	0.123252698211277	DOWN	-1.54186898198036	0.156905027058937	MAPK signaling pathway: MAP3K4
hsa04630__36	0.123252698211277	UP	1.54186898198036	0.156905027058937	Jak-STAT signaling pathway: GFAP
hsa04724__52	0.123252698211277	UP	1.54186898198036	0.156905027058937	Glutamatergic synapse: CACNA1A
hsa05130__9	0.125328858660072	DOWN	-1.53339051939287	0.159440030753064	Pathogenic Escherichia coli infection: TLR4
hsa04922__36	0.127734878715165	UP	1.52370084786433	0.162390958799591	Glucagon signaling pathway: GYS1
hsa04330__19	0.128341961343287	UP	1.52127842998219	0.163052430942554	Notch signaling pathway: DTX2
hsa04923__43	0.128646342528261	UP	1.52006722104112	0.163328701088245	Regulation of lipolysis in adipocytes: C00219
hsa05223__22	0.131411074481132	UP	1.5091663405715	0.166726137035818	Non-small cell lung cancer: BAD*
hsa04722__33	0.131721088850861	UP	1.50795513163043	0.166894083581097	Neurotrophin signaling pathway: BAD
hsa05321__83	0.131721088850861	DOWN	-1.50795513163043	0.166894083581097	Inflammatory bowel disease (IBD): IL2
hsa05168__92 93	0.132031669735465	DOWN	-1.50674392268937	0.167174870237829	Herpes simplex infection: IRF9 STAT1
hsa04932__96	0.132654533363797	DOWN	-1.50432150480723	0.16785041628995	Non-alcoholic fatty liver disease (NAFLD): IL6*
hsa04727__13	0.135803038569154	DOWN	-1.49220941539654	0.171718647019812	GABAergic synapse: CACNA1A
hsa04115__30	0.137078480300211	UP	1.48736457963227	0.173214838254268	p53 signaling pathway: SERPINE1
hsa04923__16	0.137398779982685	DOWN	-1.4861533706912	0.173502894884049	Regulation of lipolysis in adipocytes: PLIN1
hsa04650__14	0.139657060907944	UP	1.47767490810372	0.176236143348573	Natural killer cell mediated cytotoxicity: CSF2
hsa04213__2	0.140633596201795	UP	1.47404128128051	0.177230400578922	Longevity regulating pathway - multiple species: RPS6KB1
hsa05169__32	0.140633596201795	DOWN	-1.47404128128051	0.177230400578922	Epstein-Barr virus infection: CR2
hsa03320__39	0.140960272175159	DOWN	-1.47283007233944	0.177523023738018	PPAR signaling pathway: MMP1
hsa03320__23	0.141615373798124	DOWN	-1.47040765445731	0.178109295426155	PPAR signaling pathway: ACADL
hsa04350__41	0.141615373798124	DOWN	-1.47040765445731	0.178109295426155	TGF-beta signaling pathway: SMAD4***
hsa04623__9	0.141943800566272	DOWN	-1.46919644551624	0.178402943989315	Cytosolic DNA-sensing pathway: IKBKE
hsa05152__20	0.142602345493424	UP	1.4667740276341	0.179110833677904	Tuberculosis: FCGR1A
hsa04270__24	0.143263360366067	DOWN	-1.46435160975196	0.179820877840909	Vascular smooth muscle contraction: ACTA2
hsa04919__25	0.144592311209087	UP	1.45950677398769	0.181367792230891	Thyroid hormone signaling pathway: MTOR
hsa05140__26	0.147278527507532	DOWN	-1.44981710245914	0.184613978109842	Leishmaniasis: C00533
hsa04722__35	0.147956006091701	DOWN	-1.447394684577	0.185339556964204	Neurotrophin signaling pathway: FOXO3
hsa05231__59	0.148635863218331	DOWN	-1.44497226669487	0.186067146560455	Choline metabolism in cancer: PLA2G4B
hsa04933__62	0.148976685094096	UP	1.4437610577538	0.186369634681629	AGE-RAGE signaling pathway in diabetic complications: AGER**
hsa04010__68	0.151379163902994	UP	1.43528259516632	0.189249134380389	MAPK signaling pathway: ATF2
hsa05212__14	0.152070978694001	UP	1.43286017728418	0.189987612344433	Pancreatic cancer: MAPK1
hsa05219__19	0.152417787484444	DOWN	-1.43164896834311	0.190294367231409	Bladder cancer: TP53
hsa05142__53	0.152765197917155	DOWN	-1.43043775940204	0.190601465395972	Chagas disease (American trypanosomiasis): AKT3
hsa05142__18	0.155566204304103	DOWN	-1.42074808787349	0.193967417310823	Chagas disease (American trypanosomiasis): FOS
hsa04919__87	0.159122070212181	UP	1.40863599846281	0.198269476080032	Thyroid hormone signaling pathway: BAD
hsa04360__101 103	0.162374628121936	UP	1.39773511799319	0.202188155229368	Axon guidance: DPYSL2 DPYSL5
hsa04630__7	0.163104184295599	UP	1.39531270011105	0.202962094232736	Jak-STAT signaling pathway: BCL2
hsa05032__38	0.163469888011379	DOWN	-1.39410149116998	0.20314809495594	Morphine addiction: CACNA1A
hsa05321__138	0.163469888011379	UP	1.39410149116998	0.20314809495594	Inflammatory bowel disease (IBD): IFNG**
hsa05211__40	0.164938885534139	UP	1.38925665540571	0.204838179721511	Renal cell carcinoma: PAK4
hsa04151__27	0.16530768309868	UP	1.38804544646464	0.205160592168044	PI3K-Akt signaling pathway: FASLG
hsa04024__9 95	0.166417799459188	DOWN	-1.38441181964143	0.20640201002232	cAMP signaling pathway: ATP1B4 FXYD1
hsa04261__20	0.167160985080131	UP	1.3819894017593	0.207186999317656	Adrenergic signaling in cardiomyocytes: ATP1B4
hsa05205__189	0.167533511797056	UP	1.38077819281823	0.207511844869261	Proteoglycans in cancer: IL12B
hsa05161__10	0.169029856256193	UP	1.37593335705395	0.209227338541098	Hepatitis B: CASP3
hsa04930__7	0.170536204485385	UP	1.37108852128968	0.210952948142224	Type II diabetes mellitus: C00002
hsa04930__10	0.171293139801019	UP	1.36866610340754	0.211749874793497	Type II diabetes mellitus: C00031
hsa04152__15	0.173196479412816	DOWN	-1.3626100587022	0.213961988702617	AMPK signaling pathway: FOXO1
hsa04917__65	0.173962225910968	UP	1.36018764082006	0.214766769045144	Prolactin signaling pathway: CYP17A1
hsa04662__35	0.174346046217976	DOWN	-1.35897643187899	0.215099291427168	B cell receptor signaling pathway: CD79B
hsa04933__27	0.174730498533055	DOWN	-1.35776522293792	0.215432156655912	AGE-RAGE signaling pathway in diabetic complications: TNF
hsa04066__62	0.175115583331955	UP	1.35655401399686	0.215623971874668	HIF-1 signaling pathway: NPPA
hsa04650__39	0.175115583331955	DOWN	-1.35655401399686	0.215623971874668	Natural killer cell mediated cytotoxicity: FAS
hsa04670__10	0.178609886257788	DOWN	-1.34565313352724	0.219782564687875	Leukocyte transendothelial migration: BCAR1
hsa05162__78	0.180968073562738	DOWN	-1.33838587988083	0.222538619256796	Measles: FAS
hsa05120__18	0.181363341916116	DOWN	-1.33717467093976	0.222878822407052	Epithelial cell signaling in Helicobacter pylori infection: CCL5
hsa04917__33	0.181759250673507	DOWN	-1.33596346199869	0.223219367330405	Prolactin signaling pathway: CSN2
hsa04210__99	0.182155800290728	UP	1.33475225305762	0.223560253916576	Apoptosis: BID**
hsa04310__31	0.183748416434138	DOWN	-1.32990741729335	0.22536767263691	Wnt signaling pathway: MMP7
hsa04740__39	0.184148177147595	DOWN	-1.32869620835228	0.225710648963033	Olfactory transduction: PRKG1*
hsa05200__193	0.184949629733962	DOWN	-1.32627379047014	0.226545211388601	Pathways in cancer: NOS2
hsa05152__24 25	0.186156643210486	DOWN	-1.32264016364693	0.227875135239416	Tuberculosis: ITGB2 ITGAM
hsa05321__152	0.187369468857115	DOWN	-1.31900653682373	0.229210437488619	Inflammatory bowel disease (IBD): FOXP3*
hsa04912__33	0.188181254150789	UP	1.31658411894159	0.230053725796573	GnRH signaling pathway: ELK1
hsa04621__43	0.190632175805743	DOWN	-1.30931686529518	0.232747146419098	NOD-like receptor signaling pathway: MAPK1
hsa04919__103	0.190632175805743	DOWN	-1.30931686529518	0.232747146419098	Thyroid hormone signaling pathway: CCND1
hsa04530__20 37	0.19104293730463	DOWN	-1.30810565635411	0.233097194282727	Tight junction: ACTB TJP3
hsa04072__57	0.191866413789975	DOWN	-1.30568323847197	0.233950026937938	Phospholipase D signaling pathway: C06124
hsa04012__3	0.195186428493096	DOWN	-1.29599356694342	0.23784390346208	ErbB signaling pathway: ELK1
hsa04917__45	0.196022976177013	DOWN	-1.29357114906129	0.238708471961508	Prolactin signaling pathway: SLC2A2
hsa05169__30	0.198548377936509	DOWN	-1.28630389541488	0.241627203460298	Epstein-Barr virus infection: FGR
hsa05200__205	0.200245144033525	DOWN	-1.2814590596506	0.243534385526857	Pathways in cancer: SLC2A1
hsa05200__53	0.201952472171294	UP	1.27661422388633	0.245451937393183	Pathways in cancer: BCL2L1
hsa04213__13	0.203670387772421	DOWN	-1.27176938812205	0.247379869828299	Longevity regulating pathway - multiple species: RPS6KB1*
hsa04931__104	0.20410152391066	UP	1.27055817918098	0.247743387227474	Insulin resistance: C00369*
hsa04921__23	0.204533323723197	DOWN	-1.26934697023992	0.248107240333045	Oxytocin signaling pathway: C00219
hsa05217__10	0.204965787597229	UP	1.26813576129885	0.248471428964641	Basal cell carcinoma: PTCH1*
hsa04210__69	0.208887908445072	DOWN	-1.25723488082923	0.253062785279362	Apoptosis: PTPN13
hsa05161__29	0.209766827645596	UP	1.25481246294709	0.253963833212677	Hepatitis B: NFKB1
hsa04931__47	0.211090221874718	UP	1.25117883612389	0.255401498327492	Insulin resistance: AKT2*
hsa04213__52	0.212864125068247	DOWN	-1.24633400035961	0.257382040542623	Longevity regulating pathway - multiple species: SOD2
hsa04370__28	0.213309277854346	DOWN	-1.24512279141854	0.257754426423354	VEGF signaling pathway: SHC2
hsa05231__18	0.21644416975079	UP	1.23664432883106	0.261374418355871	Choline metabolism in cancer: CHKA
hsa04950__8	0.217797797685286	UP	1.23301070200786	0.262671413254591	Maturity onset diabetes of the young: NEUROD1
hsa05169__64	0.217797797685286	UP	1.23301070200786	0.262671413254591	Epstein-Barr virus infection: NFKB2
hsa05161__130	0.222813147242797	UP	1.2196874036561	0.268547725252864	Hepatitis B: FASLG*
hsa04520__34	0.225119974002473	DOWN	-1.21363135895076	0.270980417136865	Adherens junction: RHOA
hsa05160__7	0.225119974002473	DOWN	-1.21363135895076	0.270980417136865	Hepatitis C: IRF3
hsa05200__75	0.22931515048756	UP	1.20273047848114	0.275853500490477	Pathways in cancer: MAPK8
hsa03320__27	0.229784692914875	DOWN	-1.20151926954007	0.276064858047986	PPAR signaling pathway: CPT1C
hsa05210__39	0.229784692914875	UP	1.20151926954007	0.276064858047986	Colorectal cancer: BAD
hsa05132__20	0.23166970038936	DOWN	-1.1966744337758	0.278151672224669	Salmonella infection: ACTB
hsa04066__60	0.232616311003826	DOWN	-1.19425201589366	0.279109864863466	HIF-1 signaling pathway: NOS3
hsa05200__195	0.23356566271244	DOWN	-1.19182959801152	0.280070121401835	Pathways in cancer: BIRC8
hsa04723__46	0.239319465773207	UP	1.1772950907187	0.286786528181031	Retrograde endocannabinoid signaling: ADCY1
hsa04210__3	0.240288069517553	DOWN	-1.17487267283656	0.287763723788071	Apoptosis: BCL2L1
hsa04210__24	0.241259432439859	DOWN	-1.17245025495443	0.288742976786302	Apoptosis: CASP10
hsa05016__48	0.243699925151355	DOWN	-1.16639421024908	0.291292722238802	Huntington's disease: HIP1
hsa05016__46	0.243699925151355	DOWN	-1.16639421024908	0.291292722238802	Huntington's disease: HTT**
hsa04072__36	0.244680961903725	DOWN	-1.16397179236695	0.292279419845581	Phospholipase D signaling pathway: MTOR
hsa04211__23	0.247640691923909	DOWN	-1.15670453872053	0.295626975937119	Longevity regulating pathway - mammal: SOD2
hsa05213__31	0.255149378964293	UP	1.1385364046045	0.304397259094544	Endometrial cancer: MYC
hsa05220__50	0.256162371817847	DOWN	-1.13611398672237	0.305411863353893	Chronic myeloid leukemia: MAPK1
hsa05152__77	0.256669914480691	DOWN	-1.1349027777813	0.305822935516309	Tuberculosis: IL12A
hsa05205__451	0.257178154920752	DOWN	-1.13369156884023	0.30623431755139	Proteoglycans in cancer: KDR**
hsa04152__82	0.262814912625651	DOWN	-1.12036827048847	0.312748081585559	AMPK signaling pathway: HMGCR
hsa04024__91	0.263331542476989	DOWN	-1.11915706154741	0.313164536907761	cAMP signaling pathway: GRIA1
hsa05110__14	0.263848872732466	UP	1.11794585260634	0.313185111727293	Vibrio cholerae infection: C00238*
hsa05110__15	0.263848872732466	UP	1.11794585260634	0.313185111727293	Vibrio cholerae infection: C01330
hsa05110__16	0.263848872732466	UP	1.11794585260634	0.313185111727293	Vibrio cholerae infection: C00698
hsa04152__24	0.264885635212373	DOWN	-1.1155234347242	0.314217240255081	AMPK signaling pathway: SIRT1
hsa03320__29	0.266446036644306	UP	1.11188980790099	0.315868834608613	PPAR signaling pathway: OLR1
hsa04728__24	0.269060738329729	DOWN	-1.10583376319565	0.318767419496571	Dopaminergic synapse: SLC6A3
hsa04915__40	0.270111534521172	UP	1.10341134531351	0.319810695252225	Estrogen signaling pathway: CREB3**
hsa04666__27	0.271165141620332	UP	1.10098892743138	0.320855983063352	Fc gamma R-mediated phagocytosis: ARPC5
hsa04917__47	0.273811465679668	DOWN	-1.09493288272603	0.32378335054254	Prolactin signaling pathway: INS
hsa04530__5 10	0.275407705051747	DOWN	-1.09129925590283	0.325466086661781	Tight junction: IGSF5 MAGI1
hsa04662__24	0.278619203882166	DOWN	-1.08403200225642	0.329054358324696	B cell receptor signaling pathway: FOS
hsa04261__72	0.280234471044586	DOWN	-1.08039837543321	0.33075412757084	Adrenergic signaling in cardiomyocytes: ATP2B1
hsa04621__21 30	0.285118386531735	DOWN	-1.06949749496359	0.336307249399329	NOD-like receptor signaling pathway: NLRP3 PYCARD
hsa05168__91 92	0.290059540987654	DOWN	-1.05859661449398	0.341920876735133	Herpes simplex infection: STAT1 IRF9
hsa04930__13	0.297859729367625	DOWN	-1.04163968931901	0.350895568327127	Type II diabetes mellitus: C00162
hsa04970__39	0.298422122425444	UP	1.04042848037795	0.351337824584843	Salivary secretion: KCNN4
hsa05200__188	0.301811770874418	DOWN	-1.03316122673153	0.355106022212293	Pathways in cancer: KLK3
hsa05140__16	0.30579883159118	DOWN	-1.02468276414405	0.359571967809654	Leishmaniasis: STAT1
hsa04530__20 62	0.309820525571474	UP	1.01620430155657	0.364073025358849	Tight junction: ACTB SHROOM1
hsa04917__44	0.310975968585794	DOWN	-1.01378188367444	0.365202403107942	Prolactin signaling pathway: PRLR**
hsa04961__5	0.313876998527396	DOWN	-1.00772583896909	0.368379063231091	Endocrine and other factor-regulated calcium reabsorption: TRPV5
hsa04622__21 22 23	0.314459334214005	DOWN	-1.00651463002802	0.368602051770502	RIG-I-like receptor signaling pathway: CHUK IKBKB IKBKG
hsa05210__53	0.314459334214005	DOWN	-1.00651463002802	0.368602051770502	Colorectal cancer: CCND1*
hsa04919__89	0.315626135387241	UP	1.00409221214589	0.369739095007871	Thyroid hormone signaling pathway: CASP9
hsa05142__67	0.31738166175247	UP	1.00045858532268	0.371563951671583	Chagas disease (American trypanosomiasis): IFNGR1*
hsa04662__6	0.319143577700479	DOWN	-0.996824958499475	0.373394011518805	B cell receptor signaling pathway: NFKB1
hsa04068__48	0.320321738062545	DOWN	-0.994402540617338	0.374539231997213	FoxO signaling pathway: FASLG
hsa05142__7	0.321502738133201	UP	0.991980122735201	0.375452855781407	Chagas disease (American trypanosomiasis): C1QA
hsa05160__77	0.321502738133201	DOWN	-0.991980122735201	0.375452855781407	Hepatitis C: NFKB1*
hsa04961__17	0.325062775404627	DOWN	-0.984712869088789	0.379374506202046	Endocrine and other factor-regulated calcium reabsorption: CALB1
hsa03320__10	0.328648364346217	UP	0.977445615442378	0.383321090382708	PPAR signaling pathway: PLIN1
hsa05321__122	0.329849237622224	DOWN	-0.97502319756024	0.384483075367344	Inflammatory bowel disease (IBD): IL4**
hsa05169__117	0.330450738511746	DOWN	-0.973811988619172	0.384945404627137	Epstein-Barr virus infection: CDKN1A
hsa05142__29	0.331052948842176	UP	0.972600779678103	0.385407986911059	Chagas disease (American trypanosomiasis): NOS2
hsa04068__96	0.334074640361806	DOWN	-0.96654473497276	0.388444461163264	FoxO signaling pathway: CCNG2
hsa05200__201	0.334074640361806	UP	0.96654473497276	0.388444461163264	Pathways in cancer: PDGFB
hsa05152__76	0.335288281219873	DOWN	-0.964122317090623	0.389614520972258	Tuberculosis: TNF*
hsa05142__21	0.337724070388284	DOWN	-0.959277481326348	0.391960178047922	Chagas disease (American trypanosomiasis): TICAM1
hsa05200__184	0.337724070388284	UP	0.959277481326348	0.391960178047922	Pathways in cancer: GLI1
hsa05164__47	0.338946217608033	DOWN	-0.956855063444211	0.393135767213268	Influenza A: CIITA
hsa04530__22 33	0.341399014332604	DOWN	-0.952010227679936	0.395736426854388	Tight junction: MYL12B CGN
hsa04668__20	0.345099455132237	DOWN	-0.944742974033525	0.399779208503991	TNF signaling pathway: IKBKG
hsa05160__56	0.346959230749901	DOWN	-0.941109347210319	0.401686010215073	Hepatitis C: MAPK1
hsa05169__60	0.351949749650104	UP	0.93141967568177	0.407212795315606	Epstein-Barr virus infection: NFKB1
hsa05014__51	0.352576744927142	DOWN	-0.930208466740701	0.407687202288062	Amyotrophic lateral sclerosis (ALS): DERL1
hsa04510__43	0.355722314136047	UP	0.924152422035358	0.411071481095715	Focal adhesion: BAD
hsa04210__85	0.357618125180301	DOWN	-0.920518795212152	0.413008271182413	Apoptosis: FASLG*
hsa04920__10	0.360155746566797	DOWN	-0.915673959447878	0.415683444593987	Adipocytokine signaling pathway: PCK1
hsa04921__80	0.362704643084834	UP	0.910829123683603	0.418111671384296	Oxytocin signaling pathway: KCNJ2
hsa04976__36	0.362704643084834	UP	0.910829123683603	0.418111671384296	Bile secretion: SLC10A1
hsa05162__81	0.363983316416754	UP	0.908406705801466	0.419328419096922	Measles: TNFRSF10D
hsa04550__17	0.365264804738142	DOWN	-0.905984287919329	0.420289386468443	Signaling pathways regulating pluripotency of stem cells: AKT3
hsa04550__25	0.365264804738142	UP	0.905984287919329	0.420289386468443	Signaling pathways regulating pluripotency of stem cells: MAPK1
hsa05110__13	0.367835898185693	DOWN	-0.901139452155054	0.422988771536669	Vibrio cholerae infection: C00238
hsa05164__31 32 33	0.369125918345746	DOWN	-0.898717034272917	0.423953562627638	Influenza A: NLRP3 PYCARD CASP1
hsa05223__21	0.369126146066427	DOWN	-0.898717034272917	0.423953562627638	Non-small cell lung cancer: FOXO3*
hsa04330__11	0.369772162244459	UP	0.897505825331848	0.424436098263493	Notch signaling pathway: PTCRA
hsa04152__53	0.373012771923591	UP	0.891449780626505	0.427894382444706	AMPK signaling pathway: G6PC
hsa05164__19	0.376924641273773	DOWN	-0.884182526980094	0.432117999361452	Influenza A: NFKB1
hsa04668__36	0.378234199872897	UP	0.881760109097956	0.433354915586081	TNF signaling pathway: CREB3
hsa05145__13	0.380203783983987	DOWN	-0.878126482274751	0.435346075628222	Toxoplasmosis: GNAI1
hsa04064__25	0.384161816722004	DOWN	-0.870859228628339	0.439610264080783	NF-kappa B signaling pathway: NFKB2
hsa04210__31 32 33	0.390145933099595	DOWN	-0.859958348158721	0.446186371451088	Apoptosis: TRAF2 RIPK1 TRADD
hsa04152__94	0.39551243476248	DOWN	-0.850268676630172	0.452048579634246	AMPK signaling pathway: MLYCD
hsa05150__66	0.396860997603223	DOWN	-0.847846258748035	0.453314172946174	Staphylococcus aureus infection: IL10
hsa04210__59	0.400244521104309	DOWN	-0.841790214042692	0.456901248575332	Apoptosis: PMAIP1
hsa04024__109	0.405010476891109	DOWN	-0.833311751455212	0.462061133016632	cAMP signaling pathway: BDNF
hsa04810__26 80	0.407063372336524	UP	0.829678124632006	0.464121405716219	Regulation of actin cytoskeleton: PFN3 ACTB
hsa04727__49	0.411877515114015	UP	0.821199662044525	0.469041142862455	GABAergic synapse: GABRR3
hsa05164__41 42	0.41187753364718	UP	0.821199662044525	0.469041142862455	Influenza A: STAT1 IRF9
hsa04666__50 52	0.413951041219364	DOWN	-0.817566035221319	0.470831723033406	Fc gamma R-mediated phagocytosis: DNM2 AMPH
hsa05215__34	0.413951041219364	UP	0.817566035221319	0.470831723033406	Prostate cancer: BAD
hsa05161__92	0.414643580729248	DOWN	-0.816354826280251	0.471334112637784	Hepatitis B: NFKBIA
hsa04722__34	0.415336804835841	UP	0.815143617339182	0.471551574795496	Neurotrophin signaling pathway: GSK3B
hsa05016__22 9	0.415336804835841	UP	0.815143617339182	0.471551574795496	Huntington's disease: DLG4 HTT
hsa05162__27 28	0.419510506732724	UP	0.80787636369277	0.476002561685259	Measles: STAT1 IRF9
hsa04670__54	0.420208513330213	UP	0.806665154751702	0.476506817469807	Leukocyte transendothelial migration: RAC1*
hsa04064__96	0.427226018184786	UP	0.794553065341016	0.484172308907848	NF-kappa B signaling pathway: BCL2A1
hsa04270__46	0.428637668336084	UP	0.792130647458878	0.485186854700905	Vascular smooth muscle contraction: ITPR1*
hsa05100__33	0.428637668336084	DOWN	-0.792130647458878	0.485186854700905	Bacterial invasion of epithelial cells: DNM1
hsa04650__40	0.430760222527397	UP	0.788497020635673	0.487295880872353	Natural killer cell mediated cytotoxicity: TNFRSF10D
hsa04340__15	0.432888862086343	DOWN	-0.784863393812467	0.489409249013381	Hedgehog signaling pathway: HHIP
hsa03320__25	0.434311330590323	DOWN	-0.782440975930329	0.490722182909932	PPAR signaling pathway: EHHADH
hsa05215__12	0.440745761901959	DOWN	-0.771540095460712	0.497693080897705	Prostate cancer: KLK3
hsa04022__19	0.441464056357685	UP	0.770328886519643	0.498204781919574	cGMP-PKG signaling pathway: CNGB1
hsa04662__36	0.442183020788437	UP	0.769117677578575	0.498716624286598	B cell receptor signaling pathway: CD79A
hsa05162__23	0.442902654763395	UP	0.767906468637506	0.4992286072588	Measles: IRF3
hsa04010__119	0.446510852557024	UP	0.761850423932163	0.502993940020772	MAPK signaling pathway: NFATC3
hsa04742__46	0.447234422589714	DOWN	-0.760639214991094	0.503507177978474	Taste transduction: P2RY1
hsa05110__51	0.448683777675371	UP	0.758216797108957	0.504836418114984	Vibrio cholerae infection: PDIA4
hsa04014__42	0.453777209492959	DOWN	-0.749738334521477	0.510261745444207	Ras signaling pathway: PLA2G4B
hsa04520__64	0.458903094972389	DOWN	-0.741259871933996	0.515717054696841	Adherens junction: CTNND1**
hsa04740__16	0.460373571746547	UP	0.738837454051859	0.517060335512111	Olfactory transduction: PRKG1
hsa05223__23	0.461109797384755	UP	0.73762624511079	0.5175778430621	Non-small cell lung cancer: CASP9*
hsa04210__64	0.46332241738788	DOWN	-0.733992618287585	0.519440824744527	Apoptosis: TNFRSF10D*
hsa04530__11 62	0.46332241738788	DOWN	-0.733992618287585	0.519440824744527	Tight junction: TJP1 SHROOM1
hsa05142__64	0.46702323105035	UP	0.727936573582242	0.523277669137512	Chagas disease (American trypanosomiasis): CASP8
hsa04725__25	0.469995647752133	UP	0.723091737817967	0.525980835096044	Cholinergic synapse: CACNA1A
hsa04930__15	0.469995647752133	DOWN	-0.723091737817967	0.525980835096044	Type II diabetes mellitus: C00031*
hsa04666__29	0.471485766685745	DOWN	-0.72066931993583	0.527334378334831	Fc gamma R-mediated phagocytosis: WAS
hsa05200__49	0.472231801969079	UP	0.719458110994761	0.527854584116537	Pathways in cancer: CASP9
hsa04370__36	0.474473804742775	DOWN	-0.715824484171555	0.529730409454352	VEGF signaling pathway: NOS3
hsa04728__36	0.474473804742775	UP	0.715824484171555	0.529730409454352	Dopaminergic synapse: TH
hsa04660__34	0.476721641690945	DOWN	-0.712190857348349	0.531923969558958	T cell receptor signaling pathway: FOS
hsa04933__56	0.481989200801464	DOWN	-0.703712394760869	0.537482319469407	AGE-RAGE signaling pathway in diabetic complications: NFATC1
hsa05213__11	0.488808027901724	DOWN	-0.692811514291251	0.544762920775409	Endometrial cancer: FOXO3
hsa04933__58	0.491092468275972	DOWN	-0.689177887468046	0.546984438583611	AGE-RAGE signaling pathway in diabetic complications: CCL2
hsa04014__37	0.491855220930979	DOWN	-0.687966678526977	0.547185293149384	Ras signaling pathway: FASLG
hsa05162__58	0.491855220930979	DOWN	-0.687966678526977	0.547185293149384	Measles: STAT3
hsa05162__93	0.504918724595519	UP	0.66737612652881	0.561385966576912	Measles: TP53
hsa04740__42	0.506467539526342	UP	0.664953708646673	0.562774989219395	Olfactory transduction: PDE2A
hsa05166__74	0.509572647961554	DOWN	-0.660108872882399	0.565890665200804	HTLV-I infection: NFKB1
hsa05145__29	0.512687610087307	DOWN	-0.655264037118124	0.569013596783254	Toxoplasmosis: C06314
hsa04668__138	0.514248929985769	DOWN	-0.652841619235987	0.570409527416328	TNF signaling pathway: NFKB1*
hsa04152__77	0.515812635014541	DOWN	-0.65041920135385	0.571806454980721	AMPK signaling pathway: CCND1
hsa05200__216	0.516595411634542	DOWN	-0.649207992412781	0.572336543904071	Pathways in cancer: IL6
hsa04620__29	0.519732663289853	UP	0.644363156648507	0.575472996064605	Toll-like receptor signaling pathway: CXCL8
hsa04520__73	0.52209203566802	UP	0.640729529825301	0.577744955842291	Adherens junction: PARD3
hsa04024__34	0.525246408868191	UP	0.635884694061026	0.580893468077299	cAMP signaling pathway: ATP2B1
hsa05152__90	0.527618572265487	DOWN	-0.63225106723782	0.583173704286383	Tuberculosis: CR1
hsa05142__84	0.532379232372425	UP	0.624983813591409	0.588089698781767	Chagas disease (American trypanosomiasis): NFKB1*
hsa04210__114	0.535565043383978	DOWN	-0.620138977827134	0.591261290551407	Apoptosis: HRK
hsa04010__62	0.537161543032556	DOWN	-0.617716559944997	0.592675595630166	MAPK signaling pathway: MEF2C
hsa04621__21 31 41	0.537960688866907	DOWN	-0.616505351003928	0.593208999049835	NOD-like receptor signaling pathway: NLRP3 CARD8 CASP1
hsa04922__37	0.545179750136755	DOWN	-0.605604470534311	0.600816862467427	Glucagon signaling pathway: PYGB
hsa04630__35	0.547596745727345	DOWN	-0.601970843711105	0.603126779145183	Jak-STAT signaling pathway: MTOR
hsa04151__37	0.557317394662838	UP	0.587436336418281	0.613114393777209	PI3K-Akt signaling pathway: G6PC
hsa05215__30	0.557317394662838	DOWN	-0.587436336418281	0.613114393777209	Prostate cancer: TP53
hsa04913__45	0.558945634440101	DOWN	-0.585013918536144	0.614545843834377	Ovarian steroidogenesis: ACOT2
hsa05010__50	0.559760619734866	DOWN	-0.583802709595076	0.615081990925037	Alzheimer's disease: ERN1
hsa04261__37	0.560576180916987	DOWN	-0.582591500654007	0.615618143742267	Adrenergic signaling in cardiomyocytes: CREB3
hsa04210__72	0.56384416867817	UP	0.577746664889732	0.618845322982641	Apoptosis: BCL2A1
hsa05145__23	0.569585134840078	UP	0.569268202302252	0.624781359232053	Toxoplasmosis: CIITA
hsa04261__34	0.571230519361343	UP	0.566845784420115	0.625855478647209	Adrenergic signaling in cardiomyocytes: AKT3
hsa04530__20 31	0.571230519361343	UP	0.566845784420115	0.625855478647209	Tight junction: ACTB MLLT4
hsa04520__10	0.572054058959738	DOWN	-0.565634575479046	0.626392527264189	Adherens junction: NLK
hsa05166__83	0.57287816235523	DOWN	-0.564423366537978	0.626929567306626	HTLV-I infection: NFKB2
hsa04024__76	0.576180197398305	DOWN	-0.559578530773703	0.629809535143348	cAMP signaling pathway: C00416
hsa05166__26	0.576180197398305	DOWN	-0.559578530773703	0.629809535143348	HTLV-I infection: NFATC1
hsa04725__43	0.577834576177671	UP	0.557156112891566	0.630883886483349	Cholinergic synapse: CREB3
hsa04910__14	0.577834576177671	UP	0.557156112891566	0.630883886483349	Insulin signaling pathway: C00369
hsa04115__3	0.581980273116991	UP	0.551100068186223	0.635041192326845	p53 signaling pathway: GADD45G
hsa05152__81	0.583642434171639	DOWN	-0.548677650304086	0.636485277892344	Tuberculosis: IFNA1
hsa04913__47	0.584474343219182	DOWN	-0.547466441363017	0.63665350197614	Ovarian steroidogenesis: INSR
hsa04913__51	0.584474343219182	DOWN	-0.547466441363017	0.63665350197614	Ovarian steroidogenesis: INSR*
hsa04540__11	0.585306803474739	DOWN	-0.546255232421948	0.637190894396891	Gap junction: C00780
hsa05321__75	0.586139814081481	DOWN	-0.54504402348088	0.637728263265259	Inflammatory bowel disease (IBD): IL10
hsa04530__4 37 11	0.591149386839774	DOWN	-0.537776769834468	0.642806538120333	Tight junction: OCLN TJP3 TJP1
hsa05221__29	0.593661532890549	UP	0.534143143011262	0.645164846906502	Acute myeloid leukemia: RPS6KB1
hsa04261__3	0.594499999404713	UP	0.532931934070193	0.645702600509512	Adrenergic signaling in cardiomyocytes: RYR2
hsa04670__39	0.597018640109173	UP	0.529298307246988	0.648063561389449	Leukocyte transendothelial migration: MAPK14
hsa04261__39	0.607141392723428	UP	0.514763799954164	0.658291215768795	Adrenergic signaling in cardiomyocytes: SCN1B
hsa04740__10	0.607141392723428	UP	0.514763799954164	0.658291215768795	Olfactory transduction: ANO2
hsa04660__14	0.607988404615796	DOWN	-0.513552591013095	0.65844969007094	T cell receptor signaling pathway: NFKB1
hsa04723__67	0.607988404615796	DOWN	-0.513552591013095	0.65844969007094	Retrograde endocannabinoid signaling: PRKACA
hsa04912__26	0.608835942908216	UP	0.512341382072027	0.658987751569435	GnRH signaling pathway: PLD1
hsa04919__29	0.611381707005368	DOWN	-0.508707755248821	0.66136224954697	Thyroid hormone signaling pathway: HIF1A
hsa04662__16	0.617340075055508	DOWN	-0.500229292661341	0.66703967856774	B cell receptor signaling pathway: VAV3
hsa04912__20	0.617340075055508	UP	0.500229292661341	0.66703967856774	GnRH signaling pathway: PLA2G4B
hsa04660__43	0.619047125730718	DOWN	-0.497806874779203	0.668499740947137	T cell receptor signaling pathway: RHOA
hsa04921__60	0.621611556743122	UP	0.494173247955998	0.670498343926708	Oxytocin signaling pathway: ELK1
hsa05219__10	0.621611556743122	UP	0.494173247955998	0.670498343926708	Bladder cancer: EGFR
hsa04925__3	0.625037954304926	UP	0.489328412191723	0.673807410292	Aldosterone synthesis and secretion: ITPR1
hsa04650__116	0.625895825240459	UP	0.488117203250654	0.674345330061251	Natural killer cell mediated cytotoxicity: FCGR3A
hsa04932__97	0.626754202879778	DOWN	-0.486905994309586	0.674883178917537	Non-alcoholic fatty liver disease (NAFLD): TNF*
hsa04912__43	0.628472474424842	UP	0.484483576427449	0.676345807241855	GnRH signaling pathway: PTK2B
hsa04360__19	0.631915055551518	UP	0.479638740663174	0.679661356257185	Axon guidance: CDC42
hsa04071__89	0.637093905698523	DOWN	-0.472371487016762	0.684839501606135	Sphingolipid signaling pathway: C00533
hsa04726__71	0.63795878231827	DOWN	-0.471160278075694	0.685377102330492	Serotonergic synapse: CACNA1A
hsa04725__54	0.639690013773344	UP	0.468737860193557	0.686844306217207	Cholinergic synapse: CHRM1*
hsa04064__54	0.649246685534297	UP	0.455414561841802	0.696707322740688	NF-kappa B signaling pathway: CCL13
hsa04933__43	0.654483983763255	DOWN	-0.44814730819539	0.701526186817545	AGE-RAGE signaling pathway in diabetic complications: CASP3
hsa05211__23	0.654483983763255	DOWN	-0.44814730819539	0.701526186817545	Renal cell carcinoma: PDGFB
hsa04950__1	0.655358531538688	UP	0.446936099254321	0.702063101916302	Maturity onset diabetes of the young: HNF1B
hsa05162__27 70	0.656233552221955	DOWN	-0.445724890313253	0.702599911467267	Measles: STAT1 GNB2L1
hsa04917__34	0.657109044784409	DOWN	-0.444513681372184	0.70313661455006	Prolactin signaling pathway: ELF5
hsa05162__44	0.661493549646168	UP	0.438457636666841	0.707425372672254	Measles: PRKCQ
hsa04921__11	0.665889696079031	UP	0.432401591961498	0.711721694500853	Oxytocin signaling pathway: PRKACA
hsa05231__50	0.666770310869463	UP	0.431190383020429	0.712257768120364	Choline metabolism in cancer: WASF2
hsa04380__16	0.668532917552075	UP	0.428767965138292	0.713734859136562	Osteoclast differentiation: NFKB1
hsa04380__38	0.669414907335187	UP	0.427556756197223	0.713865272918738	Osteoclast differentiation: FOS
hsa04668__47	0.669414907335187	UP	0.427556756197223	0.713865272918738	TNF signaling pathway: CASP7
hsa04910__9	0.670297353336971	UP	0.426345547256155	0.714400866091985	Insulin signaling pathway: ELK1
hsa04520__7 68	0.675601550489875	UP	0.419078293609743	0.719645869257639	Adherens junction: CDH1 CTNNB1
hsa04550__60	0.676487160258036	UP	0.417867084668674	0.720180948512663	Signaling pathways regulating pluripotency of stem cells: MAPK14
hsa04961__13	0.679146671416585	DOWN	-0.414233457845469	0.722602828760908	Endocrine and other factor-regulated calcium reabsorption: ATP2B1
hsa05321__94	0.680921902968781	UP	0.411811039963331	0.724081638754012	Inflammatory bowel disease (IBD): IL22
hsa05132__55	0.684477665024009	DOWN	-0.406966204199057	0.727451093088299	Salmonella infection: IL18
hsa05223__7	0.686258178148207	DOWN	-0.40454378631692	0.728931100475117	Non-small cell lung cancer: FOXO3
hsa04530__11 43	0.68804043436892	UP	0.402121368434782	0.730411285976949	Tight junction: TJP1 ACTN4
hsa04066__53	0.693397573843717	UP	0.394854114788371	0.735682688454175	HIF-1 signaling pathway: EGF*
hsa05200__198	0.694291931261708	UP	0.393642905847302	0.73621587970697	Pathways in cancer: BCL2L1*
hsa05130__55	0.696081922568425	DOWN	-0.391220487965165	0.737697649467609	Pathogenic Escherichia coli infection: ACTB
hsa04360__31	0.70415772445884	UP	0.380319607495547	0.745835605557024	Axon guidance: CDC42*
hsa05160__71	0.70595692499838	DOWN	-0.37789718961341	0.747320034970116	Hepatitis C: MAPK8
hsa04931__67	0.70685704302735	UP	0.376685980672341	0.747851567482202	Insulin resistance: IKBKB**
hsa04666__40	0.709560252437733	DOWN	-0.373052353849135	0.750289090788127	Fc gamma R-mediated phagocytosis: PLA2G6
hsa05212__10	0.714977422992897	UP	0.365785100202724	0.755592001014428	Pancreatic cancer: BCL2L1
hsa04115__27	0.720408988946916	DOWN	-0.358517846556312	0.760904154149104	p53 signaling pathway: THBS1
hsa04024__3	0.725854700943036	UP	0.3512505929099	0.766225271388744	cAMP signaling pathway: RYR2
hsa05164__99	0.726763677290277	UP	0.350039383968832	0.766754042464026	Influenza A: FDPS
hsa04931__140	0.729492910408	UP	0.346405757145626	0.769201559291039	Insulin resistance: G00369
hsa04724__33 70 69	0.730403418894753	UP	0.345194548204557	0.769729682615391	Glutamatergic synapse: ITPR1 HOMER3 HOMER3
hsa05164__70	0.736787554941334	DOWN	-0.336716085617077	0.775587571840206	Influenza A: RNASEL
hsa05168__83	0.736787554941334	DOWN	-0.336716085617077	0.775587571840206	Herpes simplex infection: RNASEL
hsa04911__24	0.738614957944952	DOWN	-0.33429366773494	0.777075871208603	Insulin secretion: INS
hsa04024__62	0.740443838693221	DOWN	-0.331871249852802	0.778128620192708	cAMP signaling pathway: BAD
hsa04650__15	0.740443838693221	UP	0.331871249852802	0.778128620192708	Natural killer cell mediated cytotoxicity: TNF
hsa04621__44	0.741358830239535	UP	0.330660040911734	0.778654690899993	NOD-like receptor signaling pathway: MAPK14
hsa04024__123	0.743189909698764	UP	0.328237623029596	0.780141810236859	cAMP signaling pathway: PAK1
hsa05161__30	0.745939251824355	DOWN	-0.324603996206391	0.782590650015613	Hepatitis B: MYC
hsa05210__16	0.76712272008483	UP	0.296746190561812	0.804365843213949	Colorectal cancer: MAPK8
hsa04923__31	0.768047829848163	DOWN	-0.295534981620744	0.804886710699776	Regulation of lipolysis in adipocytes: PRKACA*
hsa04115__64	0.772678311758764	UP	0.2894789369154	0.808837073980344	p53 signaling pathway: PMAIP1
hsa04390__76	0.772678311758764	DOWN	-0.2894789369154	0.808837073980344	Hippo signaling pathway: MYC
hsa04670__28 41 49	0.77453278342725	DOWN	-0.287056519033263	0.810326893129066	Leukocyte transendothelial migration: ACTB CTNNA1 CTNNB1
hsa05132__68	0.775460502612805	DOWN	-0.285845310092195	0.810395041384572	Salmonella infection: NOS2
hsa05220__25	0.775460502612805	UP	0.285845310092195	0.810395041384572	Chronic myeloid leukemia: BCL2L1*
hsa04728__60	0.77824557857319	DOWN	-0.282211683268989	0.81246893549617	Dopaminergic synapse: CACNA1A
hsa05032__31	0.779174572519477	UP	0.28100047432792	0.81246893549617	Morphine addiction: GABRR3
hsa05032__33	0.779174572519477	UP	0.28100047432792	0.81246893549617	Morphine addiction: GABRR3*
hsa05032__55	0.779174572519477	UP	0.28100047432792	0.81246893549617	Morphine addiction: GABRR3**
hsa04012__25	0.791279750628744	UP	0.265254758094028	0.823720028493856	ErbB signaling pathway: CDKN1B
hsa04910__46	0.791279750628744	UP	0.265254758094028	0.823720028493856	Insulin signaling pathway: FBP1
hsa04933__59	0.791279750628744	UP	0.265254758094028	0.823720028493856	AGE-RAGE signaling pathway in diabetic complications: SERPINE1
hsa05218__9	0.795014720130057	UP	0.260409922329754	0.827149866624794	Melanoma: CCND1
hsa05162__25 70	0.796883974067709	DOWN	-0.257987504447616	0.828635853499294	Measles: IFNAR1 GNB2L1
hsa05215__35	0.803435476311056	UP	0.249509041860136	0.834575379729658	Prostate cancer: CASP9
hsa04670__18	0.804372507353975	DOWN	-0.248297832919067	0.834575379729658	Leukocyte transendothelial migration: CDH5
hsa05132__54	0.804372545338164	DOWN	-0.248297832919067	0.834575379729658	Salmonella infection: IL1B
hsa05152__129	0.804372545338164	DOWN	-0.248297832919067	0.834575379729658	Tuberculosis: IFNB1
hsa04726__41	0.812818664015449	UP	0.23739695244945	0.841943919341251	Serotonergic synapse: HTR3C
hsa04742__57	0.812818664015449	UP	0.23739695244945	0.841943919341251	Taste transduction: HTR3C
hsa05162__28 34	0.812818664015449	DOWN	-0.23739695244945	0.841943919341251	Measles: IRF9 STAT1
hsa04062__59	0.817520445398631	DOWN	-0.231340907744107	0.846347612619299	Chemokine signaling pathway: FOXO3
hsa05205__81	0.821286612048011	UP	0.226496071979832	0.849778383280954	Proteoglycans in cancer: CTTN
hsa04210__73	0.824113947969942	DOWN	-0.222862445156626	0.852234511962312	Apoptosis: TRAF1
hsa04210__61	0.835445778492979	UP	0.208327937863803	0.863477787562326	Apoptosis: APAF1
hsa05169__103	0.844915241642693	DOWN	-0.196215848453117	0.87278490326917	Epstein-Barr virus infection: NFKB1*
hsa05150__14	0.853456932619379	DOWN	-0.185314967983499	0.881123943072425	Staphylococcus aureus infection: FPR1
hsa05210__40	0.858209925558009	UP	0.179258923278156	0.885544453664744	Colorectal cancer: CASP9
hsa04912__17	0.861064160437268	UP	0.17562529645495	0.888001952503637	GnRH signaling pathway: MAPK14
hsa04727__17 37	0.865825235495422	UP	0.169569251749607	0.892422170869939	GABAergic synapse: GABRA1 GPHN
hsa04211__62	0.866778040849487	UP	0.168358042808538	0.892914440107558	Longevity regulating pathway - mammal: EHMT2
hsa04911__4	0.870591184808774	DOWN	-0.163513207044264	0.896351143153801	Insulin secretion: CACNA1C
hsa04931__144	0.878226417699499	DOWN	-0.153823535515715	0.903717107807973	Insulin resistance: C00533*
hsa04014__33	0.87918163379337	DOWN	-0.152612326574646	0.904204865844413	Ras signaling pathway: BCL2L1
hsa04612__18	0.883004243298673	UP	0.147767490810372	0.90763948203403	Antigen processing and presentation: KIR2DS2
hsa04612__39	0.883960325104474	UP	0.146556281869303	0.908125451542541	Antigen processing and presentation: PSME3
hsa04010__86	0.890657553577481	DOWN	-0.138077819281823	0.914505761296223	MAPK signaling pathway: MAP4K2
hsa04920__28	0.893530212882052	UP	0.134444192458617	0.91695427089316	Adipocytokine signaling pathway: SLC2A1
hsa04151__34	0.907913723430122	UP	0.116276058342588	0.931206269828165	PI3K-Akt signaling pathway: GYS1
hsa04010__79	0.910794206616035	DOWN	-0.112642431519382	0.933651017038478	MAPK signaling pathway: HSPB1
hsa04670__15	0.911754612756096	DOWN	-0.111431222578313	0.934125909143241	Leukocyte transendothelial migration: PECAM1
hsa04668__48	0.912715182660313	UP	0.110220013637245	0.934600451345356	TNF signaling pathway: CASP3
hsa04913__64	0.915597599772221	DOWN	-0.106586386814039	0.937041334407409	Ovarian steroidogenesis: PLA2G4B
hsa04012__23	0.917519830290459	UP	0.104163968931901	0.938497420313431	ErbB signaling pathway: RPS6KB1
hsa04670__55	0.918481127099966	DOWN	-0.102952759990833	0.938969552677277	Leukocyte transendothelial migration: RAC2
hsa04670__2	0.924251361725972	DOWN	-0.0956855063444211	0.944354708364927	Leukocyte transendothelial migration: MMP2
hsa05152__6	0.925213463418904	UP	0.0944742974033525	0.944823966176153	Tuberculosis: IL10
hsa04151__28	0.926175674503809	DOWN	-0.0932630884622838	0.945292825851525	PI3K-Akt signaling pathway: BCL2L11
hsa04670__76	0.934840265866818	DOWN	-0.0823622079926663	0.953618273378801	Leukocyte transendothelial migration: CDC42
hsa05160__22 23	0.939657331399562	UP	0.0763061632873231	0.958012005263037	Hepatitis C: STAT1 IRF9
hsa03320__26	0.953156304703602	UP	0.0593492381123625	0.971247666235395	PPAR signaling pathway: CPT2
hsa04933__28	0.957015794430188	DOWN	-0.054504402348088	0.974651857850582	AGE-RAGE signaling pathway in diabetic complications: VCAM1
hsa04261__36	0.968599949815711	DOWN	-0.0399698950552645	0.985915116849253	Adrenergic signaling in cardiomyocytes: MAPK1
hsa04024__25	0.974394666375062	DOWN	-0.0327026414088528	0.991185804571975	cAMP signaling pathway: CFTR
hsa04550__66	0.975360592151986	UP	0.0314914324677842	0.991185804571975	Signaling pathways regulating pluripotency of stem cells: MYC
hsa04742__27	0.975360592151986	DOWN	-0.0314914324677842	0.991185804571975	Taste transduction: CALHM1
hsa04912__19	0.977292550695562	UP	0.0290690145856469	0.992076014455409	GnRH signaling pathway: MAPK7
hsa05321__92	0.977292550695562	DOWN	-0.0290690145856469	0.992076014455409	Inflammatory bowel disease (IBD): IL17F
hsa04152__52	0.979224642452736	DOWN	-0.0266465967035097	0.992964437759682	AMPK signaling pathway: PCK1
hsa04670__45	0.979224642452736	DOWN	-0.0266465967035097	0.992964437759682	Leukocyte transendothelial migration: PXN
hsa04610__17	0.985021603702502	DOWN	-0.0193793430570979	0.997228229179419	Complement and coagulation cascades: PLG
hsa04723__10	0.985021603702502	DOWN	-0.0193793430570979	0.997228229179419	Retrograde endocannabinoid signaling: CACNA1A
hsa04723__21	0.985021603702502	DOWN	-0.0193793430570979	0.997228229179419	Retrograde endocannabinoid signaling: CACNA1A*
hsa05152__112	0.989853021932156	UP	0.0133232983517548	1	Tuberculosis: IFNGR1
hsa04622__9 35	0.995651199418931	DOWN	-0.00605604470534311	1	RIG-I-like receptor signaling pathway: IRF3 PIN1
hsa04152__33	1	0	0	1	AMPK signaling pathway: CPT1C
hsa04152__41	1	0	0	1	AMPK signaling pathway: FBP1
hsa04211__2	1	0	0	1	Longevity regulating pathway - mammal: RPS6KB1
hsa04911__41	1	0	0	1	Insulin secretion: ABCC8
hsa04911__35	1	0	0	1	Insulin secretion: TRPM4
hsa04922__67	1	0	0	1	Glucagon signaling pathway: FBP1
hsa04922__60	1	0	0	1	Glucagon signaling pathway: CPT1C*
hsa04924__34	1	0	0	1	Renin secretion: REN
hsa04924__47	1	0	0	1	Renin secretion: KCNMA1
hsa04931__151	1	0	0	1	Insulin resistance: CPT1A
hsa04931__29	1	0	0	1	Insulin resistance: CPT1B
hsa04960__15	1	0	0	1	Aldosterone-regulated sodium reabsorption: C00762
hsa05030__13	1	0	0	1	Cocaine addiction: SLC6A3
hsa05031__15	1	0	0	1	Amphetamine addiction: MAOA
hsa05031__77	1	0	0	1	Amphetamine addiction: MAOA*
hsa05034__7	1	0	0	1	Alcoholism: GRIN3A
hsa05034__75	1	0	0	1	Alcoholism: SLC29A1
hsa05140__37	1	0	0	1	Leishmaniasis: ELK1
hsa05140__55	1	0	0	1	Leishmaniasis: JUN
hsa05140__41 57	1	0	0	1	Leishmaniasis: NOS2 CYBA
hsa05211__12	1	0	0	1	Renal cell carcinoma: EGLN2