p.value	UP.DOWN	statistic	FDRp.value	path.name
hsa04530__11 24 23	8.46205130718098e-23	DOWN	-9.82947736541277	6.05962510269655e-20	Tight junction: TJP1 YBX3 CDK4
hsa04211__43 59 60 61	9.16898675455597e-23	UP	9.82135662679762	6.05962510269655e-20	Longevity regulating pathway - mammal: ULK3 RB1CC1 ATG13 ATG101
hsa04750__8	9.67476067487475e-23	DOWN	-9.81594280105419	6.05962510269655e-20	Inflammatory mediator regulation of TRP channels: ASIC2
hsa04610__17	2.94346189243812e-21	UP	9.46539758416718	1.38269122397281e-18	Complement and coagulation cascades: PLG
hsa05150__40	1.35693083650143e-20	DOWN	-9.30433626830018	5.09934608357236e-18	Staphylococcus aureus infection: FCGR1A
hsa04931__35	1.30168856754351e-18	DOWN	-8.80626429990474	4.07645469735709e-16	Insulin resistance: C00369
hsa04151__105 62	3.7830964967893e-18	UP	8.68580667711345	1.01549118820959e-15	PI3K-Akt signaling pathway: CCND1 CDK2
hsa04960__3	8.46575527684967e-18	DOWN	-8.59377163947516	1.98839427065007e-15	Aldosterone-regulated sodium reabsorption: SCNN1A
hsa04530__11 43	6.40105740900795e-17	DOWN	-8.35827021963601	1.33639854128066e-14	Tight junction: TJP1 ACTN4
hsa04950__13	8.81886800271117e-17	DOWN	-8.32037343943201	1.65706529770943e-14	Maturity onset diabetes of the young: INS
hsa05231__59	1.40628770306082e-16	DOWN	-8.26488172556187	2.40219508550116e-14	Choline metabolism in cancer: PLA2G4B
hsa05161__213	1.66682087973427e-16	UP	8.24457987902401	2.60770713966515e-14	Hepatitis B: E2F1
hsa03460__27	1.80416140583539e-16	UP	8.23510568397301	2.60770713966515e-14	Fanconi anemia pathway: BRCA1
hsa04530__11 36 14	2.0199108093046e-16	DOWN	-8.22157111961444	2.71100886477381e-14	Tight junction: TJP1 CTNNB1 CTNNA1
hsa04921__34 35	2.64696601467102e-16	DOWN	-8.18908816515386	3.3157660943779e-14	Oxytocin signaling pathway: MYL9 ACTB
hsa04530__11 13	4.43131675139992e-16	DOWN	-8.12682916910443	5.20402760992528e-14	Tight junction: TJP1 EPB41
hsa05214__52	1.21435872304166e-15	UP	8.00366463344143	1.34222355329134e-13	Glioma: E2F1*
hsa05214__35	1.82180671248963e-15	UP	7.95358674531471	1.90176378487112e-13	Glioma: E2F1
hsa04261__36	1.96656465314839e-15	DOWN	-7.94411255026371	1.94482893856096e-13	Adrenergic signaling in cardiomyocytes: MAPK1
hsa04110__10 11 12 13 14 9 15 16 17 18 19 20	4.02628213484179e-15	UP	7.85478442549714	3.78269206568386e-13	Cell cycle: ORC3 ORC5 ORC4 ORC2 ORC1 ORC6 MCM7 MCM6 MCM5 MCM4 MCM3 MCM2
hsa04010__13	4.34219742523617e-15	UP	7.84531023044614	3.86877542071633e-13	MAPK signaling pathway: STMN1
hsa04540__1	4.63230331696334e-15	DOWN	-7.837189491831	3.86877542071633e-13	Gap junction: C00681
hsa05212__34	4.78444380277974e-15	UP	7.83312912252343	3.86877542071633e-13	Pancreatic cancer: E2F1
hsa04152__44	4.94149069170793e-15	DOWN	-7.82906875321585	3.86877542071633e-13	AMPK signaling pathway: SLC2A4
hsa04115__52 53	6.8192294664234e-15	UP	7.78846506014014	5.12533286696383e-13	p53 signaling pathway: CDK4 CCND1
hsa04022__43	9.49586047025746e-15	DOWN	-7.74650791062857	6.86258531677453e-13	cGMP-PKG signaling pathway: MAPK1
hsa05200__168	1.00151440384961e-14	UP	7.73974062844928	6.96979838827191e-13	Pathways in cancer: E2F1
hsa04360__114	1.30610409700866e-14	DOWN	-7.70590421755285	8.55281766759215e-13	Axon guidance: RAF1
hsa04925__18	1.32001975710576e-14	DOWN	-7.70455076111699	8.55281766759215e-13	Aldosterone synthesis and secretion: PDE2A
hsa04024__9 95	1.4215985632138e-14	DOWN	-7.69507656606599	8.90394566759578e-13	cAMP signaling pathway: ATP1B4 FXYD1
hsa04740__21	2.12269947733847e-14	DOWN	-7.64364522150342	1.28662977997386e-12	Olfactory transduction: PDE1A
hsa04742__54	2.48483655667968e-14	DOWN	-7.62334337496556	1.40236877981714e-12	Taste transduction: P2RX2*
hsa04742__40	2.48483655667968e-14	DOWN	-7.62334337496556	1.40236877981714e-12	Taste transduction: P2RX2
hsa04722__38	2.53754861701877e-14	DOWN	-7.62063646209385	1.40236877981714e-12	Neurotrophin signaling pathway: ATF4
hsa05166__132 136	4.10256592017186e-14	UP	7.55837746604442	2.20249181828655e-12	HTLV-I infection: CREBBP TP53
hsa03460__25 40	4.55190427412777e-14	UP	7.54484290168585	2.29802325729621e-12	Fanconi anemia pathway: MLH1 PMS2
hsa04014__42	4.64741265445749e-14	DOWN	-7.54213598881413	2.29802325729621e-12	Ras signaling pathway: PLA2G4B
hsa04970__18	4.64741265445749e-14	DOWN	-7.54213598881413	2.29802325729621e-12	Salivary secretion: VAMP2
hsa05223__28	6.14680339935921e-14	UP	7.50559266504599	2.96149835574255e-12	Non-small cell lung cancer: RB1
hsa05218__21	6.81524665939146e-14	UP	7.49205810068742	3.12337767634062e-12	Melanoma: RB1
hsa05220__40	6.81524665939146e-14	UP	7.49205810068742	3.12337767634062e-12	Chronic myeloid leukemia: RB1
hsa04261__8 38	7.40101062966385e-14	DOWN	-7.48123044920056	3.31107118408057e-12	Adrenergic signaling in cardiomyocytes: ATP2A2 PLN
hsa05164__20	1.31387709810061e-13	DOWN	-7.40543688879256	5.74133736588613e-12	Influenza A: ATF2
hsa03460__28	1.39674145461442e-13	UP	7.39731615017741	5.96472089368296e-12	Fanconi anemia pathway: RAD51C
hsa03460__48	1.53075304248903e-13	UP	7.3851350422547	6.39174437074864e-12	Fanconi anemia pathway: RAD51
hsa04022__23	1.66042791618979e-13	UP	7.37430739076784	6.78248707504483e-12	cGMP-PKG signaling pathway: CACNA1C
hsa04972__23	2.31934174620367e-13	DOWN	-7.32964332838456	9.27243221514189e-12	Pancreatic secretion: KCNMA1
hsa04664__3 4 5	2.86605489292992e-13	DOWN	-7.30122074323155	1.09904824187417e-11	Fc epsilon RI signaling pathway: FCER1G MS4A2 FCER1A
hsa04261__20	2.86606513314711e-13	DOWN	-7.30122074323155	1.09904824187417e-11	Adrenergic signaling in cardiomyocytes: ATP1B4
hsa04261__23	3.43400746327651e-13	DOWN	-7.27685852738612	1.29050000469931e-11	Adrenergic signaling in cardiomyocytes: SLC9A1
hsa04664__46	4.32272363889971e-13	DOWN	-7.24572902936141	1.59262700342991e-11	Fc epsilon RI signaling pathway: PLA2G4B
hsa04920__3	4.40991043670764e-13	DOWN	-7.2430221164897	1.59350417511032e-11	Adipocytokine signaling pathway: C15493
hsa04911__54	4.97047484760404e-13	DOWN	-7.22678063925941	1.76217400729207e-11	Insulin secretion: RAB3A
hsa04972__51	5.22417878783918e-13	DOWN	-7.22001335708012	1.81782073006478e-11	Pancreatic secretion: CLCA1
hsa05166__60	6.50001717147785e-13	UP	7.19023731549127	2.22064223003762e-11	HTLV-I infection: POLD3
hsa04151__99	7.4663126702651e-13	UP	7.17128892538927	2.48571675663925e-11	PI3K-Akt signaling pathway: MYB
hsa03460__7	7.5404925560637e-13	UP	7.16993546895341	2.48571675663925e-11	Fanconi anemia pathway: FANCI
hsa04919__32	9.84078889613959e-13	DOWN	-7.13339214518526	3.18807626480108e-11	Thyroid hormone signaling pathway: PLN
hsa05221__21	1.12917697738462e-12	DOWN	-7.11444375508326	3.59614159407745e-11	Acute myeloid leukemia: PIM1
hsa04622__5 33	1.29521227168532e-12	UP	7.09549536498126	4.05617309749454e-11	RIG-I-like receptor signaling pathway: MAVS TMEM173
hsa04728__70 73	1.51441057177556e-12	DOWN	-7.07384006200755	4.66488108912504e-11	Dopaminergic synapse: KIF5A GRIA1
hsa04921__56	1.71896599645235e-12	DOWN	-7.0562451283414	5.20957597957091e-11	Oxytocin signaling pathway: JUN
hsa05014__5	2.2342168639986e-12	UP	7.01970180457326	6.6636404562752e-11	Amyotrophic lateral sclerosis (ALS): TOMM40
hsa05211__48	2.32244133553682e-12	DOWN	-7.01428797882983	6.81854260855263e-11	Renal cell carcinoma: JUN
hsa05161__45	2.39084334876708e-12	UP	7.01022760952226	6.91137638820515e-11	Hepatitis B: PCNA
hsa03320__43	2.46122014314714e-12	DOWN	-7.00616724021469	7.00701916511132e-11	PPAR signaling pathway: ILK
hsa04666__38	2.55822444877415e-12	DOWN	-7.00075341447126	7.1375197241575e-11	Fc gamma R-mediated phagocytosis: CFL1
hsa04071__48	2.58303002257962e-12	DOWN	-6.9993999580354	7.1375197241575e-11	Sphingolipid signaling pathway: SMPD1
hsa04261__39	2.63342881043706e-12	DOWN	-6.99669304516369	7.17132280407425e-11	Adrenergic signaling in cardiomyocytes: SCN1B
hsa05212__10	2.84473435715701e-12	UP	6.98586539367683	7.63607979585431e-11	Pancreatic cancer: BCL2L1
hsa05220__25	4.4239743950051e-12	UP	6.9236063976274	1.17079547721332e-10	Chronic myeloid leukemia: BCL2L1*
hsa04022__44	5.10492512587473e-12	DOWN	-6.90330455108954	1.33224365437758e-10	cGMP-PKG signaling pathway: BAD
hsa04020__8	5.20314994091266e-12	DOWN	-6.90059763821783	1.3392765395856e-10	Calcium signaling pathway: PDE1A
hsa05219__21	5.50907265148425e-12	UP	6.89247689960269	1.39340268790784e-10	Bladder cancer: RB1
hsa04916__8	5.5617456941505e-12	DOWN	-6.89112344316683	1.39340268790784e-10	Melanogenesis: TYR*
hsa04068__47	5.94453191620183e-12	DOWN	-6.88164924811583	1.45062019097964e-10	FoxO signaling pathway: GADD45G
hsa04068__54	5.94453191620183e-12	DOWN	-6.88164924811583	1.45062019097964e-10	FoxO signaling pathway: GADD45G*
hsa04014__33	6.17473765885523e-12	UP	6.8762354223724	1.48747846935756e-10	Ras signaling pathway: BCL2L1
hsa04924__49	6.66166424180905e-12	DOWN	-6.86540777088554	1.58446419118471e-10	Renin secretion: PDE1A
hsa05205__431	6.91904446809757e-12	DOWN	-6.85999394514211	1.62511056944442e-10	Proteoglycans in cancer: CDKN1A*
hsa04930__3	7.05136393081476e-12	DOWN	-6.8572870322704	1.63574232419765e-10	Type II diabetes mellitus: SLC2A4
hsa04722__33	8.3594118086548e-12	DOWN	-6.83292481642497	1.9103928921196e-10	Neurotrophin signaling pathway: BAD
hsa04972__39	8.43867003969809e-12	DOWN	-6.83157135998911	1.9103928921196e-10	Pancreatic secretion: KCNMA1*
hsa04911__56	8.84613836257037e-12	DOWN	-6.82480407780983	1.97879690277021e-10	Insulin secretion: CAMK2A*
hsa04728__74	9.44914610110005e-12	DOWN	-6.81532988275883	2.08881712046671e-10	Dopaminergic synapse: GRIN2A
hsa04261__34	9.62870909123616e-12	DOWN	-6.81262296988711	2.10376097470148e-10	Adrenergic signaling in cardiomyocytes: AKT3
hsa05219__27	9.90433829921963e-12	DOWN	-6.80856260057954	2.13910938669353e-10	Bladder cancer: RPS6KA5
hsa04210__58	1.03809921044254e-11	UP	6.80179531840025	2.21657774593356e-10	Apoptosis: BID*
hsa04925__5	1.14026851111665e-11	DOWN	-6.78826075404168	2.40737587908786e-10	Aldosterone synthesis and secretion: KCNK3
hsa04923__16	1.32456746545756e-11	DOWN	-6.76660545106797	2.76540251954973e-10	Regulation of lipolysis in adipocytes: PLIN1
hsa04914__34	1.36223458771726e-11	DOWN	-6.7625450817604	2.81278987947332e-10	Progesterone-mediated oocyte maturation: MAPK14
hsa04923__66	1.4273571893131e-11	DOWN	-6.75577779958111	2.91522191165144e-10	Regulation of lipolysis in adipocytes: LIPE
hsa04210__64	1.45425147111834e-11	UP	6.7530708867094	2.93821345616275e-10	Apoptosis: TNFRSF10D*
hsa05166__136 139	1.7038121789032e-11	UP	6.73006212729982	3.40581179165863e-10	HTLV-I infection: TP53 TBPL2
hsa04710__7	1.81835336399084e-11	DOWN	-6.72058793224882	3.59651154835662e-10	Circadian rhythm: PER1
hsa04022__37 38	2.05141428219511e-11	DOWN	-6.70299299858268	4.01521607942147e-10	cGMP-PKG signaling pathway: ATP2A1 PLN
hsa05222__44	2.29235900597522e-11	UP	6.6867515213524	4.4405593528118e-10	Small cell lung cancer: RB1
hsa03320__65	2.73159294549979e-11	DOWN	-6.66103584907111	5.2374113720348e-10	PPAR signaling pathway: ME1
hsa04622__45	2.8602519602782e-11	UP	6.65426856689182	5.37441343336275e-10	RIG-I-like receptor signaling pathway: MAPK14
hsa05215__39	2.8602519602782e-11	UP	6.65426856689182	5.37441343336275e-10	Prostate cancer: RB1
hsa04022__65	3.22316604421107e-11	DOWN	-6.63667363322568	5.9375774481104e-10	cGMP-PKG signaling pathway: PDE2A
hsa04066__89	3.22316604421107e-11	DOWN	-6.63667363322568	5.9375774481104e-10	HIF-1 signaling pathway: CDKN1A
hsa05164__78	3.31311037423596e-11	UP	6.63261326391811	6.04401397397025e-10	Influenza A: GSK3B
hsa04919__40	4.08925526399061e-11	DOWN	-6.60148376589339	7.38493408776181e-10	Thyroid hormone signaling pathway: RCAN2
hsa04068__58	4.1267593358967e-11	DOWN	-6.60013030945754	7.38493408776181e-10	FoxO signaling pathway: KLF2
hsa04115__11 12	4.35895415285853e-11	UP	6.59200957084239	7.72686306907658e-10	p53 signaling pathway: CDK2 CCNE1
hsa05034__62	4.47979724950232e-11	DOWN	-6.58794920153482	7.86685890823819e-10	Alcoholism: NPY
hsa04650__116	5.83040397898999e-11	UP	6.54869896489496	1.0143823219002e-09	Natural killer cell mediated cytotoxicity: FCGR3A
hsa04012__56	6.38276516132534e-11	DOWN	-6.53516440053639	1.10029502184682e-09	ErbB signaling pathway: JUN
hsa05031__98	7.85464746684948e-11	DOWN	-6.50403490251168	1.34171659911002e-09	Amphetamine addiction: FOS
hsa05168__79	8.14249117385957e-11	UP	6.49862107676825	1.37835503744884e-09	Herpes simplex infection: EIF2S1
hsa04810__8 79	1.01898121544114e-10	DOWN	-6.46478466587182	1.69439442815389e-09	Regulation of actin cytoskeleton: ARPC5 ACTB
hsa04810__8 82	1.01898121544114e-10	DOWN	-6.46478466587182	1.69439442815389e-09	Regulation of actin cytoskeleton: ARPC5 ACTB*
hsa04370__38	1.06558853748625e-10	DOWN	-6.45801738369253	1.75635163327777e-09	VEGF signaling pathway: BAD
hsa04910__17	1.15478870975937e-10	DOWN	-6.44583627576982	1.88682433533726e-09	Insulin signaling pathway: C00031
hsa04261__52	1.27376203576877e-10	DOWN	-6.43094825497539	2.0632748838013e-09	Adrenergic signaling in cardiomyocytes: MAPK14
hsa04723__73	1.29664486781234e-10	DOWN	-6.42824134210367	2.06474212425372e-09	Retrograde endocannabinoid signaling: MAPK14*
hsa04723__68	1.29664486781234e-10	DOWN	-6.42824134210367	2.06474212425372e-09	Retrograde endocannabinoid signaling: MAPK14
hsa04722__46	1.35562410018537e-10	DOWN	-6.42147405992439	2.14051906239354e-09	Neurotrophin signaling pathway: ATF4*
hsa05152__88 89	1.59045712502944e-10	UP	6.39711184407896	2.49039078160859e-09	Tuberculosis: ITGAX ITGB2
hsa04152__94	1.73764759454833e-10	DOWN	-6.38357727972039	2.69838002492258e-09	AMPK signaling pathway: MLYCD
hsa04950__5	2.00124609632905e-10	DOWN	-6.36192197674667	3.08224706147728e-09	Maturity onset diabetes of the young: GCK
hsa04931__104	2.03682556117849e-10	DOWN	-6.35921506387496	3.11154083695478e-09	Insulin resistance: C00369*
hsa04115__9	2.16628705930055e-10	DOWN	-6.34974086882396	3.25636270754058e-09	p53 signaling pathway: RPRM
hsa04668__40	2.16628705930055e-10	DOWN	-6.34974086882396	3.25636270754058e-09	TNF signaling pathway: JUN
hsa04068__43	2.26364590183977e-10	DOWN	-6.34297358664467	3.37570686472772e-09	FoxO signaling pathway: CDKN1A
hsa04916__6	2.34459844554015e-10	DOWN	-6.33755976090124	3.46889801509444e-09	Melanogenesis: DCT
hsa04910__39	2.55955196095844e-10	DOWN	-6.32402519654267	3.75734229268821e-09	Insulin signaling pathway: BAD
hsa04620__18	2.91851053898885e-10	UP	6.30372335000481	4.25107077733338e-09	Toll-like receptor signaling pathway: CXCL11
hsa05031__97	2.96994003420806e-10	DOWN	-6.3010164371331	4.29270563405919e-09	Amphetamine addiction: ARC
hsa04530__14 20 43	3.12959581190892e-10	DOWN	-6.29289569851796	4.48893933631822e-09	Tight junction: CTNNA1 ACTB ACTN4
hsa04211__50	3.15700757616236e-10	DOWN	-6.2915422420821	4.49395245121899e-09	Longevity regulating pathway - mammal: PPARGC1A*
hsa04722__53	3.21253623221921e-10	DOWN	-6.28883532921038	4.53861321830068e-09	Neurotrophin signaling pathway: JUN
hsa04520__44 47	3.38490585757874e-10	DOWN	-6.28071459059524	4.74644634805258e-09	Adherens junction: ACTB TJP1
hsa05160__15 16	3.41449880373007e-10	DOWN	-6.27936113415938	4.75247648311763e-09	Hepatitis C: TRAF6 RIPK1
hsa04611__34	3.53541717675404e-10	DOWN	-6.27394730841595	4.88459476111827e-09	Platelet activation: C02198*
hsa04970__32	3.62883963691366e-10	DOWN	-6.26988693910838	4.97707275748961e-09	Salivary secretion: RYR3
hsa04921__58	3.78992603225582e-10	DOWN	-6.2631196569291	5.13097308186735e-09	Oxytocin signaling pathway: MEF2C
hsa05161__207	3.82297089654832e-10	UP	6.26176620049324	5.13097308186735e-09	Hepatitis B: CDK2
hsa05161__219	3.82297089654832e-10	UP	6.26176620049324	5.13097308186735e-09	Hepatitis B: CDK2*
hsa04622__21 22 23	5.04241491477447e-10	UP	6.21845559454581	6.67232227102904e-09	RIG-I-like receptor signaling pathway: CHUK IKBKB IKBKG
hsa04728__54	5.04241491477447e-10	DOWN	-6.21845559454581	6.67232227102904e-09	Dopaminergic synapse: CAMK2A
hsa04115__30	5.30999937389074e-10	UP	6.21033485593067	6.97726491156692e-09	p53 signaling pathway: SERPINE1
hsa05152__20	5.35589603173401e-10	UP	6.20898139949481	6.98870044696403e-09	Tuberculosis: FCGR1A
hsa04622__44	5.44893864698579e-10	UP	6.2062744866231	7.01270939567555e-09	RIG-I-like receptor signaling pathway: MAPK8
hsa05223__9	5.44893864698579e-10	DOWN	-6.2062744866231	7.01270939567555e-09	Non-small cell lung cancer: BAD
hsa05145__67	5.83701622288548e-10	DOWN	-6.19544683513624	7.46105679102164e-09	Toxoplasmosis: BAD
hsa04664__47	6.04104027397359e-10	DOWN	-6.19003300939281	7.66967207756512e-09	Fc epsilon RI signaling pathway: MAPK8
hsa04922__37	6.41494964907165e-10	DOWN	-6.18055881434181	8.0897250943662e-09	Glucagon signaling pathway: PYGB
hsa04723__40	6.58202283935896e-10	DOWN	-6.17649844503424	8.13659270733913e-09	Retrograde endocannabinoid signaling: GRIA1
hsa04724__4	6.58202283935896e-10	DOWN	-6.17649844503424	8.13659270733913e-09	Glutamatergic synapse: GRIA1
hsa05031__12	6.58202283935896e-10	DOWN	-6.17649844503424	8.13659270733913e-09	Amphetamine addiction: GRIA1
hsa05014__51	6.69575549702361e-10	UP	6.17379153216252	8.22308796007017e-09	Amyotrophic lateral sclerosis (ALS): DERL1
hsa04024__24	6.86995762729371e-10	DOWN	-6.16973116285495	8.38224050758759e-09	cAMP signaling pathway: PLN
hsa05031__55	6.92900158922122e-10	DOWN	-6.1683777064191	8.3997380555785e-09	Amphetamine addiction: GRIA1*
hsa05223__22	7.67731319964245e-10	DOWN	-6.15213622918881	9.24722532187703e-09	Non-small cell lung cancer: BAD*
hsa04550__34	8.01187143491582e-10	DOWN	-6.14536894700952	9.58873020777505e-09	Signaling pathways regulating pluripotency of stem cells: MAPK1*
hsa04620__19	8.14963983895379e-10	UP	6.14266203413781	9.69188180847732e-09	Toll-like receptor signaling pathway: CXCL10
hsa03320__40	8.36063480458076e-10	DOWN	-6.13860166483024	9.88027219987877e-09	PPAR signaling pathway: FABP4
hsa04390__17 51	8.72418980007854e-10	DOWN	-6.13183438265095	1.02454703964672e-08	Hippo signaling pathway: YWHAQ YAP1
hsa04068__88	8.87388927960828e-10	DOWN	-6.12912746977924	1.03565453145242e-08	FoxO signaling pathway: FBXO32
hsa04666__41	8.94967552606114e-10	UP	6.12777401334338	1.03805187120178e-08	Fc gamma R-mediated phagocytosis: MARCKS
hsa04022__3	9.33817599730311e-10	DOWN	-6.12100673116409	1.07646826373819e-08	cGMP-PKG signaling pathway: MYL9
hsa04390__78	9.5791194340323e-10	DOWN	-6.11694636185652	1.0975100863748e-08	Hippo signaling pathway: SOX2
hsa04750__40	9.99422835588811e-10	DOWN	-6.11017907967724	1.13813061095235e-08	Inflammatory mediator regulation of TRP channels: C00219
hsa03320__29	1.01651385135692e-09	UP	6.10747216680552	1.14373025550877e-08	PPAR signaling pathway: OLR1
hsa05166__120	1.01651385135692e-09	UP	6.10747216680552	1.14373025550877e-08	HTLV-I infection: E2F1
hsa05200__53	1.02516589925804e-09	UP	6.10611871036966	1.14659924089634e-08	Pathways in cancer: BCL2L1
hsa05213__12	1.03388973912735e-09	DOWN	-6.10476525393381	1.14951409456822e-08	Endometrial cancer: BAD
hsa05162__27 70	1.16389464541681e-09	UP	6.08581686383181	1.28644590514011e-08	Measles: STAT1 GNB2L1
hsa04620__20	1.18372203162951e-09	UP	6.08310995096009	1.30070976458003e-08	Toll-like receptor signaling pathway: IFNB1*
hsa04152__54	1.22436957522189e-09	DOWN	-6.07769612521666	1.33755257665228e-08	AMPK signaling pathway: SLC2A4*
hsa04630__31	1.38927211519767e-09	UP	6.05739427867881	1.50892618754706e-08	Jak-STAT signaling pathway: BCL2L1
hsa04931__61	1.46112810927979e-09	DOWN	-6.04927354006366	1.57785041226249e-08	Insulin resistance: ACACB
hsa05012__70	1.57575005755086e-09	DOWN	-6.03709243214095	1.69190534750746e-08	Parkinson's disease: PRKACA
hsa04914__29	1.58901227143153e-09	UP	6.03573897570509	1.69645116932946e-08	Progesterone-mediated oocyte maturation: CDK2
hsa04270__48	1.68495852806099e-09	DOWN	-6.02626478065409	1.78872151086249e-08	Vascular smooth muscle contraction: KCNMB2*
hsa04810__23	1.94207364169057e-09	DOWN	-6.00325602124452	2.05008784985201e-08	Regulation of actin cytoskeleton: GSN
hsa04110__59 15 16 17 18 19 20	2.07592790855682e-09	UP	5.99242836975766	2.17914443585378e-08	Cell cycle: CDC45 MCM7 MCM6 MCM5 MCM4 MCM3 MCM2
hsa05160__85	2.11077113484407e-09	DOWN	-5.98972145688595	2.20341053465111e-08	Hepatitis C: BAD
hsa04914__11	2.23726673899269e-09	UP	5.98024726183495	2.32255480804821e-08	Progesterone-mediated oocyte maturation: CDK1
hsa04151__32	2.55475966071407e-09	UP	5.95859195886123	2.63757879257239e-08	PI3K-Akt signaling pathway: BCL2L1
hsa05218__14	2.86823867068253e-09	DOWN	-5.93964356875923	2.94503850394124e-08	Melanoma: BAD
hsa04666__42	2.89201032827811e-09	UP	5.93829011232337	2.95330837327966e-08	Fc gamma R-mediated phagocytosis: MYO10
hsa04510__43	3.11476933225338e-09	DOWN	-5.92610900440066	3.16359544611032e-08	Focal adhesion: BAD
hsa04350__27	3.19266930964927e-09	UP	5.92204863509309	3.22528259829622e-08	TGF-beta signaling pathway: ACVR2A*
hsa05221__41	3.21905503157127e-09	DOWN	-5.92069517865723	3.23454780979809e-08	Acute myeloid leukemia: MAPK1
hsa04024__108	3.35420096673029e-09	UP	5.91392789647795	3.33467916216202e-08	cAMP signaling pathway: AMH
hsa04520__10	3.35420096673029e-09	UP	5.91392789647795	3.33467916216202e-08	Adherens junction: NLK
hsa04921__57	3.43792323361009e-09	DOWN	-5.90986752717037	3.39992513471229e-08	Oxytocin signaling pathway: FOS
hsa04630__28	3.49486463117006e-09	UP	5.90716061429866	3.43814169736572e-08	Jak-STAT signaling pathway: CCND1
hsa04630__24	3.91996998128665e-09	UP	5.88821222419666	3.83626228897792e-08	Jak-STAT signaling pathway: MCL1
hsa04360__108	4.21939710746115e-09	DOWN	-5.87603111627394	4.10790008545052e-08	Axon guidance: CFL1
hsa04210__119	4.65346231343991e-09	DOWN	-5.85978963904366	4.4840285574121e-08	Apoptosis: BCL2*
hsa04261__3	4.65346231343991e-09	DOWN	-5.85978963904366	4.4840285574121e-08	Adrenergic signaling in cardiomyocytes: RYR2
hsa04210__60	4.88649224641585e-09	UP	5.85166890042851	4.68455047500785e-08	Apoptosis: BBC3
hsa05034__61	4.92641886630199e-09	DOWN	-5.85031544399266	4.69885332476216e-08	Alcoholism: CRH
hsa04921__46	4.96666284907896e-09	DOWN	-5.8489619875568	4.71331287546432e-08	Oxytocin signaling pathway: C00942*
hsa04740__37	5.04811271479019e-09	UP	5.84625507468509	4.76653456838732e-08	Olfactory transduction: CNGB1*
hsa03320__42	5.08932354929807e-09	DOWN	-5.84490161824923	4.78141947456554e-08	PPAR signaling pathway: ACOX1
hsa04911__4	5.6557828217586e-09	DOWN	-5.82730668458309	5.28717210053951e-08	Insulin secretion: CACNA1C
hsa04022__49	5.8895996475784e-09	DOWN	-5.8205394024038	5.47849392960387e-08	cGMP-PKG signaling pathway: ATP1B4
hsa05205__195	5.93747860468307e-09	DOWN	-5.81918594596794	5.49582379221649e-08	Proteoglycans in cancer: CDKN1A
hsa04530__5 15	6.38577652904516e-09	DOWN	-5.80700483804523	5.88180102846856e-08	Tight junction: IGSF5 MPDZ
hsa04931__149	6.43757417179595e-09	DOWN	-5.80565138160937	5.90058627746566e-08	Insulin resistance: ACACB*
hsa04015__3	6.54239828018257e-09	DOWN	-5.80294446873766	5.96755648954517e-08	Rap1 signaling pathway: MAPK1
hsa04911__24	6.70275374202182e-09	DOWN	-5.79888409943008	6.08428709239565e-08	Insulin secretion: INS
hsa04530__11 20 16	6.81177420600455e-09	DOWN	-5.79617718655837	6.15352102552046e-08	Tight junction: TJP1 ACTB CTTN
hsa04068__52	6.92251845865534e-09	DOWN	-5.79347027368666	6.22364219321215e-08	FoxO signaling pathway: CAT
hsa04010__54	7.20709508868433e-09	DOWN	-5.78670299150737	6.44863412935137e-08	MAPK signaling pathway: NR4A1
hsa04270__10 3 71	7.74826465061247e-09	DOWN	-5.77452188358466	6.89999491872077e-08	Vascular smooth muscle contraction: ACTA2 MYL9 MYH11
hsa04066__30	8.95167848623738e-09	DOWN	-5.75015966773923	7.93405843190568e-08	HIF-1 signaling pathway: PDK1
hsa04115__49	9.24280334658113e-09	UP	5.7447458419958	8.11552686365699e-08	p53 signaling pathway: MDM2*
hsa05120__53	9.24280334658113e-09	DOWN	-5.7447458419958	8.11552686365699e-08	Epithelial cell signaling in Helicobacter pylori infection: GIT1
hsa04970__45	9.54101632490094e-09	DOWN	-5.73933201625237	8.33840449976227e-08	Salivary secretion: KCNMA1
hsa05152__98	1.00114632877698e-08	UP	5.73121127763723	8.70904607301826e-08	Tuberculosis: IL23A
hsa03460__16 34	1.00916616610642e-08	UP	5.72985782120137	8.73835588070948e-08	Fanconi anemia pathway: FANCM STRA13
hsa03320__23	1.04187453431024e-08	DOWN	-5.72444399545794	8.9391883560226e-08	PPAR signaling pathway: ACADL
hsa04713__60	1.04187453431024e-08	DOWN	-5.72444399545794	8.9391883560226e-08	Circadian entrainment: PER1
hsa05205__30	1.05861280902916e-08	DOWN	-5.72173708258623	9.04151576438992e-08	Proteoglycans in cancer: FLNA
hsa05205__400	1.14630129727005e-08	UP	5.70820251822765	9.70226357951837e-08	Proteoglycans in cancer: ITGA2*
hsa05010__47	1.14630256234863e-08	DOWN	-5.70820251822765	9.70226357951837e-08	Alzheimer's disease: C00533
hsa04110__48	1.1739586244085e-08	UP	5.70414214892008	9.84762613956952e-08	Cell cycle: RB1*
hsa04610__23	1.1739586244085e-08	UP	5.70414214892008	9.84762613956952e-08	Complement and coagulation cascades: BDKRB1
hsa04713__61	1.3327658337333e-08	DOWN	-5.68248684594637	1.1080827440641e-07	Circadian entrainment: FOS
hsa04921__65	1.3327658337333e-08	UP	5.68248684594637	1.1080827440641e-07	Oxytocin signaling pathway: TRPM2
hsa04010__78	1.34335588633814e-08	DOWN	-5.68113338951051	1.1119672733169e-07	MAPK signaling pathway: MAP3K4
hsa04610__45	1.44241860055445e-08	UP	5.6689522815878	1.18873006598325e-07	Complement and coagulation cascades: C4A
hsa03320__41	1.53640432116073e-08	DOWN	-5.65812463010094	1.26065664605285e-07	PPAR signaling pathway: ANGPTL4
hsa04152__64	1.548562758318e-08	DOWN	-5.65677117366508	1.26510844473023e-07	AMPK signaling pathway: ACACB
hsa04022__19	1.75628966182271e-08	DOWN	-5.63511587069137	1.42860098466012e-07	cGMP-PKG signaling pathway: CNGB1
hsa04666__27	1.84096397581954e-08	UP	5.62699513207622	1.49102211662281e-07	Fc gamma R-mediated phagocytosis: ARPC5
hsa04920__43	1.85545647535928e-08	DOWN	-5.62564167564037	1.49631017905583e-07	Adipocytokine signaling pathway: C00162
hsa05132__13	1.96005140051923e-08	DOWN	-5.61616748058937	1.57390452204087e-07	Salmonella infection: FOS
hsa05321__74	2.11946133787587e-08	UP	5.60263291623079	1.69466717185905e-07	Inflammatory bowel disease (IBD): IL5
hsa04611__25	2.2038168003227e-08	DOWN	-5.59586563405151	1.74724547164825e-07	Platelet activation: ORAI1
hsa04620__77	2.2038168003227e-08	UP	5.59586563405151	1.74724547164825e-07	Toll-like receptor signaling pathway: CXCL9
hsa03460__16 49	2.3456068719932e-08	UP	5.58503798256465	1.85184676994757e-07	Fanconi anemia pathway: FANCM C19orf40
hsa05161__100	2.36394141532425e-08	UP	5.58368452612879	1.85851293698505e-07	Hepatitis B: MMP9*
hsa05020__48	2.45772066173604e-08	DOWN	-5.57691724394951	1.92419046808417e-07	Prion diseases: SOD1
hsa03320__22	2.51571083520106e-08	DOWN	-5.57285687464194	1.94527599149909e-07	PPAR signaling pathway: ACADM
hsa04014__104	2.51571083520106e-08	UP	5.57285687464194	1.94527599149909e-07	Ras signaling pathway: BRAP*
hsa04919__26	2.51571083520106e-08	DOWN	-5.57285687464194	1.94527599149909e-07	Thyroid hormone signaling pathway: THRB
hsa04960__27	2.78271741039652e-08	DOWN	-5.55526194097579	2.14292049759633e-07	Aldosterone-regulated sodium reabsorption: KCNJ1
hsa05012__71	3.05345517853231e-08	DOWN	-5.53902046374551	2.34181317569886e-07	Parkinson's disease: PRKACA*
hsa04022__45	3.17365479999559e-08	DOWN	-5.53225318156622	2.42410462162265e-07	cGMP-PKG signaling pathway: CREB3
hsa04728__32	3.24796458739939e-08	DOWN	-5.52819281225865	2.46085704021107e-07	Dopaminergic synapse: CREB3
hsa05030__37	3.24796458739939e-08	DOWN	-5.52819281225865	2.46085704021107e-07	Cocaine addiction: PRKACA
hsa04710__11	3.27310751522399e-08	DOWN	-5.52683935582279	2.46994739803449e-07	Circadian rhythm: CRY1
hsa05169__118	3.29843920257236e-08	UP	5.52548589938693	2.47910690465339e-07	Epstein-Barr virus infection: MDM2
hsa04024__118	3.64556504551605e-08	DOWN	-5.50789096572079	2.72909032690226e-07	cAMP signaling pathway: MYL9
hsa04976__34	3.90637073022079e-08	UP	5.49570985779808	2.90121367671339e-07	Bile secretion: SLCO1B1
hsa05133__73	3.90637073022079e-08	DOWN	-5.49570985779808	2.90121367671339e-07	Pertussis: FOS
hsa04611__43	4.02800969812866e-08	DOWN	-5.49029603205465	2.97977567826132e-07	Platelet activation: MYL12B
hsa04310__31	4.48335108218035e-08	UP	5.47134764195265	3.30361438565368e-07	Wnt signaling pathway: MMP7
hsa04922__70	4.58722392314471e-08	DOWN	-5.46728727264508	3.36695068421442e-07	Glucagon signaling pathway: PFKFB1
hsa04390__12	4.98842497343764e-08	DOWN	-5.45239925185065	3.64717919264176e-07	Hippo signaling pathway: CTGF
hsa04210__61	5.02653979006368e-08	UP	5.45104579541479	3.66080165330607e-07	Apoptosis: APAF1
hsa04931__13	5.38251760331332e-08	DOWN	-5.43886468749208	3.90492300255819e-07	Insulin resistance: AKT2
hsa04152__27	5.98530688162883e-08	DOWN	-5.41991629739007	4.32553524253099e-07	AMPK signaling pathway: ADIPOR1
hsa04022__46	6.31073727013341e-08	DOWN	-5.41044210233907	4.54324725309604e-07	cGMP-PKG signaling pathway: VASP
hsa05145__23	6.40682360459653e-08	UP	5.40773518946736	4.59481738665529e-07	Toxoplasmosis: CIITA
hsa05150__1 2 3	7.01380781424258e-08	DOWN	-5.39149371223707	5.01100565892084e-07	Staphylococcus aureus infection: CFD C3 CFB
hsa04725__61	7.28283795196805e-08	DOWN	-5.38472643005779	5.18350473929847e-07	Cholinergic synapse: FOS
hsa04115__2	7.39322549807336e-08	UP	5.38201951718607	5.24221536259617e-07	p53 signaling pathway: IGFBP3
hsa04610__11	7.61888281690698e-08	UP	5.37660569144264	5.34174657200307e-07	Complement and coagulation cascades: F2R
hsa04726__10	7.61888281690698e-08	DOWN	-5.37660569144264	5.34174657200307e-07	Serotonergic synapse: PRKACA
hsa05223__23	7.61888281690698e-08	DOWN	-5.37660569144264	5.34174657200307e-07	Non-small cell lung cancer: CASP9*
hsa04020__42	7.67633108563795e-08	DOWN	-5.37525223500679	5.36201714123186e-07	Calcium signaling pathway: MYLK4
hsa04066__26	7.85120423408457e-08	UP	5.37119186569922	5.46385657623885e-07	HIF-1 signaling pathway: C01245
hsa04068__67	8.33660372924547e-08	DOWN	-5.36036421421236	5.78025033477942e-07	FoxO signaling pathway: GABARAP
hsa05152__68	8.46242153690268e-08	UP	5.35765730134064	5.8459154661177e-07	Tuberculosis: CD74
hsa05166__114 112 113	8.65460212694807e-08	DOWN	-5.35359693203307	5.95677560312653e-07	HTLV-I infection: DLG1 CTNNB1 APC2
hsa04261__72	9.18797200758158e-08	DOWN	-5.34276928054622	6.30080270154956e-07	Adrenergic signaling in cardiomyocytes: ATP2B1
hsa04510__44	9.53734322076874e-08	DOWN	-5.33600199836693	6.51660651339072e-07	Focal adhesion: BCL2
hsa04920__2	1.01988853567635e-07	DOWN	-5.32382089044421	6.94337158889804e-07	Adipocytokine signaling pathway: C00638
hsa04911__31	1.04291098994648e-07	DOWN	-5.31976052113664	7.04902787809153e-07	Insulin secretion: CAMK2A
hsa04972__18	1.04291098994648e-07	DOWN	-5.31976052113664	7.04902787809153e-07	Pancreatic secretion: PRKCA
hsa04664__23	1.07439129243811e-07	DOWN	-5.31434669539321	7.23577504835561e-07	Fc epsilon RI signaling pathway: AKT3
hsa04910__14	1.11503667833433e-07	DOWN	-5.30757941321393	7.48269256639359e-07	Insulin signaling pathway: C00369
hsa04340__50	1.15716829684773e-07	DOWN	-5.30081213103464	7.73779085329851e-07	Hedgehog signaling pathway: BCL2
hsa04270__24	1.18318236239298e-07	DOWN	-5.29675176172707	7.88368673381706e-07	Vascular smooth muscle contraction: ACTA2
hsa04152__87	1.21874943451533e-07	DOWN	-5.29133793598364	8.09197946096929e-07	AMPK signaling pathway: CD36
hsa04914__39	1.28349595738396e-07	DOWN	-5.28186374093264	8.46206632955952e-07	Progesterone-mediated oocyte maturation: PIK3R5
hsa04933__59	1.28349595738396e-07	UP	5.28186374093264	8.46206632955952e-07	AGE-RAGE signaling pathway in diabetic complications: SERPINE1
hsa04724__66	1.35156446206721e-07	DOWN	-5.27238954588164	8.84874433527627e-07	Glutamatergic synapse: PLA2G4B
hsa05131__38	1.35156446206721e-07	UP	5.27238954588164	8.84874433527627e-07	Shigellosis: CXCL8
hsa04620__21	1.36156918482996e-07	UP	5.27103608944579	8.88329339685938e-07	Toll-like receptor signaling pathway: IFNA1
hsa04520__43	1.38179398698141e-07	DOWN	-5.26832917657407	8.98405156241547e-07	Adherens junction: ACTB
hsa04971__56	1.47645845284575e-07	DOWN	-5.25614806865136	9.56643252723158e-07	Gastric acid secretion: CAMK2A
hsa04115__19	1.5317291003027e-07	UP	5.24938078647207	9.89044322841504e-07	p53 signaling pathway: RFWD2
hsa04911__25	1.5658463490616e-07	DOWN	-5.2453204171645	1.00761140064615e-06	Insulin secretion: PRKCA
hsa04971__55	1.60069792114251e-07	DOWN	-5.24126004785693	1.02652266000914e-06	Gastric acid secretion: MYLK4
hsa04012__29	1.62434776275145e-07	DOWN	-5.23855313498521	1.03814607013945e-06	ErbB signaling pathway: STAT5A*
hsa04920__26	1.6362990348236e-07	DOWN	-5.23719967854936	1.0422392835368e-06	Adipocytokine signaling pathway: NPY
hsa04022__39	1.64833531127087e-07	DOWN	-5.2358462221135	1.04635880063445e-06	cGMP-PKG signaling pathway: KCNJ8
hsa05160__53	1.77350335655224e-07	UP	5.22231165775493	1.11825933119518e-06	Hepatitis C: EIF2S1
hsa05162__74	1.77350335655224e-07	UP	5.22231165775493	1.11825933119518e-06	Measles: EIF2S1
hsa04742__47	1.78651397302375e-07	DOWN	-5.22095820131907	1.12269557033834e-06	Taste transduction: GABRA1
hsa05321__81	1.81281258893814e-07	UP	5.21825128844736	1.13542495153826e-06	Inflammatory bowel disease (IBD): IL13
hsa05212__12	2.23887764336489e-07	DOWN	-5.1790010518075	1.39762494746931e-06	Pancreatic cancer: CASP9
hsa04115__43 57	2.28811169264943e-07	UP	5.17494068249993	1.41893131039217e-06	p53 signaling pathway: CDK1 CCNB3
hsa04270__28	2.28811169264943e-07	DOWN	-5.17494068249993	1.41893131039217e-06	Vascular smooth muscle contraction: KCNMB2
hsa04742__8	2.33838254198696e-07	UP	5.17088031319235	1.44533578828733e-06	Taste transduction: PLCB2
hsa04960__4	2.40709104220143e-07	DOWN	-5.16546648744893	1.48292592403163e-06	Aldosterone-regulated sodium reabsorption: ATP1B4
hsa04520__44 52 45	2.45989541888502e-07	DOWN	-5.16140611814135	1.51050440917809e-06	Adherens junction: ACTB ACTN4 CTNNA1
hsa04913__64	2.47774350285333e-07	DOWN	-5.1600526617055	1.51650815695811e-06	Ovarian steroidogenesis: PLA2G4B
hsa04024__91	2.49571665597458e-07	DOWN	-5.15869920526964	1.52254921966761e-06	cAMP signaling pathway: GRIA1
hsa04261__4	2.72146235099543e-07	DOWN	-5.14245772803935	1.6548957144079e-06	Adrenergic signaling in cardiomyocytes: SLC8A1
hsa05223__8	2.76095534226138e-07	DOWN	-5.13975081516764	1.67349518971262e-06	Non-small cell lung cancer: CASP9
hsa04923__26 27	2.78088631373197e-07	DOWN	-5.13839735873178	1.68015607186571e-06	Regulation of lipolysis in adipocytes: PNPLA2 ABHD5
hsa04370__37	3.09745367157233e-07	DOWN	-5.11809551219392	1.86542161823218e-06	VEGF signaling pathway: CASP9
hsa04024__62	3.11975047292294e-07	DOWN	-5.11674205575807	1.87284700914448e-06	cAMP signaling pathway: BAD
hsa04151__63	3.16480989194695e-07	DOWN	-5.11403514288635	1.8938464289708e-06	PI3K-Akt signaling pathway: CASP9
hsa05030__69	3.44865315127715e-07	DOWN	-5.09779366565607	2.05714897499992e-06	Cocaine addiction: PRKACA**
hsa04151__34	3.47338560864943e-07	DOWN	-5.09644020922021	2.06534542995325e-06	PI3K-Akt signaling pathway: GYS1
hsa04012__21	3.92097758577405e-07	UP	5.07343144981064	2.32413781819225e-06	ErbB signaling pathway: GSK3B
hsa04630__1	3.94897130700828e-07	UP	5.07207799337478	2.33337015278886e-06	Jak-STAT signaling pathway: MYC
hsa04728__68	4.06288706818679e-07	DOWN	-5.06666416763135	2.3931551100699e-06	Dopaminergic synapse: CACNA1C
hsa04064__134	4.09185766820052e-07	DOWN	-5.06531071119549	2.40268767454649e-06	NF-kappa B signaling pathway: CCL21
hsa05030__78	4.12102753692575e-07	DOWN	-5.06395725475964	2.41227748968333e-06	Cocaine addiction: GRIA2
hsa04621__28	4.42397986282643e-07	UP	5.05042269040106	2.58157085784189e-06	NOD-like receptor signaling pathway: CASP8
hsa04261__37	4.55108169667768e-07	DOWN	-5.04500886465764	2.64751780435212e-06	Adrenergic signaling in cardiomyocytes: CREB3
hsa05205__352	4.71319102089522e-07	UP	5.03824158247835	2.73335985440189e-06	Proteoglycans in cancer: ITGA5*
hsa03320__62	5.20448930113195e-07	DOWN	-5.01929319237635	2.99976803866122e-06	PPAR signaling pathway: UBC
hsa04520__69	5.20449377649579e-07	UP	5.01929319237635	2.99976803866122e-06	Adherens junction: IQGAP1**
hsa04066__88	5.27831575197243e-07	DOWN	-5.01658627950464	3.03301385258599e-06	HIF-1 signaling pathway: BCL2
hsa05205__415	5.31560435198602e-07	DOWN	-5.01523282306878	3.0451282248115e-06	Proteoglycans in cancer: MAPK1******
hsa04925__3	5.46731478309403e-07	DOWN	-5.00981899732535	3.12251807824732e-06	Aldosterone synthesis and secretion: ITPR1
hsa04919__28	5.94791140652176e-07	DOWN	-4.99357752009506	3.37647297065087e-06	Thyroid hormone signaling pathway: RCAN1
hsa05030__76	5.94791140652176e-07	DOWN	-4.99357752009506	3.37647297065087e-06	Cocaine addiction: PDYN
hsa05200__226	5.9897499169123e-07	DOWN	-4.99222406365921	3.38998195598741e-06	Pathways in cancer: CDKN1A*
hsa04724__51	6.03187203855736e-07	UP	4.99087060722335	3.40356983797276e-06	Glutamatergic synapse: ADRBK1
hsa04610__52	6.65241517243315e-07	UP	4.97192221712135	3.74248146976104e-06	Complement and coagulation cascades: CPB2
hsa04530__11 62	6.69901938095459e-07	DOWN	-4.97056876068549	3.7462670883374e-06	Tight junction: TJP1 SHROOM1
hsa04724__44	6.69901938095459e-07	DOWN	-4.97056876068549	3.7462670883374e-06	Glutamatergic synapse: PRKACA*
hsa04919__87	6.74593813084496e-07	DOWN	-4.96921530424963	3.76131090440881e-06	Thyroid hormone signaling pathway: BAD
hsa05142__67	6.98532171572759e-07	UP	4.96244802207035	3.88326020824028e-06	Chagas disease (American trypanosomiasis): IFNGR1*
hsa04210__59	7.1328586440865e-07	UP	4.95838765276278	3.95358153163378e-06	Apoptosis: PMAIP1
hsa04916__4	7.23287969180243e-07	DOWN	-4.95568073989106	3.99722968849905e-06	Melanogenesis: TYR
hsa04010__58	7.33425133477557e-07	UP	4.95297382701935	4.04136605807721e-06	MAPK signaling pathway: CDC25B
hsa05169__104	7.54111655996132e-07	UP	4.94756000127592	4.13581764820676e-06	Epstein-Barr virus infection: IRF3
hsa04914__30	7.59368552752309e-07	UP	4.94620654484006	4.13581764820676e-06	Progesterone-mediated oocyte maturation: CDK1*
hsa05152__112	7.59370456961859e-07	UP	4.94620654484006	4.13581764820676e-06	Tuberculosis: IFNGR1
hsa05215__34	7.59370456961859e-07	DOWN	-4.94620654484006	4.13581764820676e-06	Prostate cancer: BAD
hsa04115__38	7.64664576087799e-07	UP	4.94485308840421	4.1526148510664e-06	p53 signaling pathway: GTSE1
hsa04668__102	8.31033022205108e-07	UP	4.92861161117392	4.50003184070143e-06	TNF signaling pathway: AKT3
hsa04917__31	9.02931631150977e-07	DOWN	-4.91237013394363	4.87531188199048e-06	Prolactin signaling pathway: GALT
hsa05213__13	9.28201916772646e-07	DOWN	-4.9069563082002	4.99739656623439e-06	Endometrial cancer: CASP9
hsa04068__44	9.34625094314287e-07	DOWN	-4.90560285176435	5.01760157776156e-06	FoxO signaling pathway: CDKN1B
hsa04725__54	1.0434040693107e-06	DOWN	-4.88394754879063	5.5856303311533e-06	Cholinergic synapse: CHRM1*
hsa04110__60 10 11 12 13 14 9	1.07244630139099e-06	DOWN	-4.8785337230472	5.72479147816381e-06	Cell cycle: CDC6 ORC3 ORC5 ORC4 ORC2 ORC1 ORC6
hsa04014__44	1.07982752120439e-06	DOWN	-4.87718026661135	5.74786377434291e-06	Ras signaling pathway: ETS1
hsa04668__120	1.10226569137565e-06	UP	4.87311989730377	5.85072664998546e-06	TNF signaling pathway: DNM1L
hsa04550__69	1.10984429115282e-06	DOWN	-4.87176644086792	5.8743589382427e-06	Signaling pathways regulating pluripotency of stem cells: ID1
hsa03320__53	1.14066316810312e-06	DOWN	-4.86635261512449	6.02052273276898e-06	PPAR signaling pathway: ADIPOQ
hsa04530__13 45 20	1.18844042804577e-06	DOWN	-4.85823187650935	6.25512482996641e-06	Tight junction: EPB41 TJP2 ACTB
hsa04390__88	1.19658823315364e-06	DOWN	-4.85687842007349	6.28041701144046e-06	Hippo signaling pathway: ID1
hsa04920__28	1.22972014663019e-06	DOWN	-4.85146459433006	6.43633469503656e-06	Adipocytokine signaling pathway: SLC2A1
hsa05222__40	1.23814000950757e-06	UP	4.8501111378942	6.46240299406865e-06	Small cell lung cancer: TRAF1
hsa04972__21	1.3164562045272e-06	DOWN	-4.83793002997149	6.85213631109865e-06	Pancreatic secretion: KCNQ1
hsa04068__45	1.32544650330052e-06	DOWN	-4.83657657353563	6.87987287210409e-06	FoxO signaling pathway: RBL2
hsa04728__44	1.33449583817668e-06	DOWN	-4.83522311709977	6.90776220367488e-06	Dopaminergic synapse: FOS
hsa04650__14	1.38064111637689e-06	UP	4.82845583492049	7.12699081778073e-06	Natural killer cell mediated cytotoxicity: CSF2
hsa04742__18	1.46759715807948e-06	DOWN	-4.81627472699777	7.55510975351054e-06	Taste transduction: PDE1A
hsa05215__13	1.51815699520923e-06	DOWN	-4.80950744481849	7.79403550272716e-06	Prostate cancer: BCL2
hsa05164__36	1.5388462811017e-06	DOWN	-4.80680053194677	7.87872523757519e-06	Influenza A: IL33
hsa04550__17	1.57038924513174e-06	UP	4.8027401626392	8.01837334674605e-06	Signaling pathways regulating pluripotency of stem cells: AKT3
hsa05034__84	1.66879147931929e-06	DOWN	-4.79055905471649	8.49772138114076e-06	Alcoholism: FOSB
hsa04723__42	1.71440379472992e-06	DOWN	-4.78514522897306	8.63636656916227e-06	Retrograde endocannabinoid signaling: KCNJ3
hsa04723__50	1.71440379472992e-06	DOWN	-4.78514522897306	8.63636656916227e-06	Retrograde endocannabinoid signaling: KCNJ3*
hsa04727__49	1.71440379472992e-06	UP	4.78514522897306	8.63636656916227e-06	GABAergic synapse: GABRR3
hsa04930__7	1.71440379472992e-06	DOWN	-4.78514522897306	8.63636656916227e-06	Type II diabetes mellitus: C00002
hsa04012__24	1.72599272850038e-06	DOWN	-4.7837917725372	8.64837423160592e-06	ErbB signaling pathway: CDKN1A
hsa04012__37 7	1.72599272850038e-06	DOWN	-4.7837917725372	8.64837423160592e-06	ErbB signaling pathway: ERBB3 ERBB3
hsa05169__93	1.93491037546571e-06	UP	4.76078301312763	9.66940583909592e-06	Epstein-Barr virus infection: PLCG1
hsa04068__68	1.96102956816309e-06	DOWN	-4.75807610025591	9.72236031287191e-06	FoxO signaling pathway: ATG12
hsa04915__12 14	1.96102956816309e-06	DOWN	-4.75807610025591	9.72236031287191e-06	Estrogen signaling pathway: ESR1 FOS
hsa04971__49	1.96102956816309e-06	DOWN	-4.75807610025591	9.72236031287191e-06	Gastric acid secretion: KCNJ1
hsa05222__39	2.04143516734894e-06	UP	4.74995536164077	1.00943596827596e-05	Small cell lung cancer: BCL2L1
hsa05215__24	2.09678811726188e-06	DOWN	-4.74454153589734	1.03408526832942e-05	Prostate cancer: CDKN1A
hsa04610__46	2.18252869871831e-06	UP	4.7364207972822	1.07355272902924e-05	Complement and coagulation cascades: C2
hsa04915__3 11	2.30210022064095e-06	DOWN	-4.72559314579534	1.12647039442301e-05	Estrogen signaling pathway: ESR1 C00951
hsa04915__12 13	2.30210022064095e-06	DOWN	-4.72559314579534	1.12647039442301e-05	Estrogen signaling pathway: ESR1 C00951*
hsa04725__50	2.44413587889594e-06	DOWN	-4.71341203787263	1.19286527699882e-05	Cholinergic synapse: BCL2
hsa05220__6	2.71766665874106e-06	UP	4.69175673489891	1.32292633465659e-05	Chronic myeloid leukemia: TP53
hsa04932__35	2.75385608126193e-06	DOWN	-4.6890498220272	1.33707896038531e-05	Non-alcoholic fatty liver disease (NAFLD): PRKAG2
hsa04913__47	2.77212376972556e-06	DOWN	-4.68769636559134	1.33902842244584e-05	Ovarian steroidogenesis: INSR
hsa04913__51	2.77212376972556e-06	DOWN	-4.68769636559134	1.33902842244584e-05	Ovarian steroidogenesis: INSR*
hsa04932__55	2.79050771082939e-06	UP	4.68634290915548	1.34445230478165e-05	Non-alcoholic fatty liver disease (NAFLD): CASP3
hsa04024__111	2.90329248006441e-06	DOWN	-4.67822217054034	1.39521395653223e-05	cAMP signaling pathway: JUN
hsa05016__52	2.92251018444429e-06	UP	4.67686871410448	1.40086648892113e-05	Huntington's disease: CASP3
hsa05162__93	2.98089834776117e-06	UP	4.67280834479691	1.42521831945121e-05	Measles: TP53
hsa05168__123	3.08070697410816e-06	UP	4.66604106261763	1.46920010262671e-05	Herpes simplex infection: CYCS
hsa05205__91	3.16285422858172e-06	UP	4.6606272368742	1.50455774569748e-05	Proteoglycans in cancer: RAC1*
hsa04919__99	3.39973535268038e-06	DOWN	-4.64573921607977	1.61315725446627e-05	Thyroid hormone signaling pathway: WNT4
hsa04115__1	3.42209421745114e-06	UP	4.64438575964391	1.61967633113116e-05	p53 signaling pathway: SIAH1
hsa04151__33	3.5129478665327e-06	UP	4.63897193390048	1.65849975909923e-05	PI3K-Akt signaling pathway: TP53
hsa05200__205	3.79959567917862e-06	UP	4.6227304566702	1.78933340380367e-05	Pathways in cancer: SLC2A1
hsa05321__152	3.95119861448071e-06	UP	4.61460971805505	1.85607554915231e-05	Inflammatory bowel disease (IBD): FOXP3*
hsa04740__13	4.24432166656379e-06	DOWN	-4.59972169726062	1.98879810759934e-05	Olfactory transduction: CNGA3
hsa05200__191	4.55821772478876e-06	UP	4.58483367646619	2.13056992658659e-05	Pathways in cancer: CCND1*
hsa04921__43	4.58783141945703e-06	UP	4.58348022003034	2.13909062956818e-05	Oxytocin signaling pathway: CACNG3
hsa04722__73 77	4.7694213261856e-06	DOWN	-4.57535948141519	2.21825313660959e-05	Neurotrophin signaling pathway: NGFRAP1 YWHAE
hsa05205__77	4.92598242991178e-06	DOWN	-4.56859219923591	2.28541258908746e-05	Proteoglycans in cancer: MIR21
hsa04722__84	4.95788409673544e-06	DOWN	-4.56723874280005	2.29454783688815e-05	Neurotrophin signaling pathway: NFKB1*
hsa05162__28 34	5.02227481504478e-06	UP	4.56453182992834	2.31863743918161e-05	Measles: IRF9 STAT1
hsa04919__46	5.05476974017895e-06	DOWN	-4.56317837349248	2.32791969161673e-05	Thyroid hormone signaling pathway: ATP1B4
hsa04012__8	5.15346695877297e-06	DOWN	-4.55911800418491	2.36757076174435e-05	ErbB signaling pathway: STAT5A
hsa05133__46	5.25400047355968e-06	DOWN	-4.55505763487734	2.4078699731265e-05	Pertussis: CFL1
hsa04072__3	5.71180201949666e-06	DOWN	-4.53746270121119	2.61130802789154e-05	Phospholipase D signaling pathway: MAPK1
hsa04660__34	5.74855571588188e-06	DOWN	-4.53610924477534	2.62173208498594e-05	T cell receptor signaling pathway: FOS
hsa04068__59	5.89784685899994e-06	DOWN	-4.53069541903191	2.68330611333193e-05	FoxO signaling pathway: S1PR1
hsa05200__194	6.16807784464012e-06	DOWN	-4.52122122398091	2.79947301209633e-05	Pathways in cancer: BCL2
hsa04970__21	6.28748279801886e-06	DOWN	-4.51716085467334	2.84679040421143e-05	Salivary secretion: ITPR1
hsa05152__69	6.49142114403592e-06	UP	4.51039357249405	2.93206257924122e-05	Tuberculosis: HLA-DMA
hsa05211__3	6.57475573418713e-06	UP	4.50768665962234	2.96258178046465e-05	Renal cell carcinoma: VEGFA
hsa04115__64	6.65911323978581e-06	UP	4.50497974675062	2.99341477931999e-05	p53 signaling pathway: PMAIP1
hsa05221__26	6.78759359816163e-06	DOWN	-4.50091937744305	3.04388743936651e-05	Acute myeloid leukemia: BAD
hsa04022__50	6.96259339994598e-06	DOWN	-4.49550555169962	3.11493166630916e-05	cGMP-PKG signaling pathway: ATP2B1
hsa05205__188	7.00701299873359e-06	UP	4.49415209526376	3.12735805810461e-05	Proteoglycans in cancer: TNF
hsa05321__138	7.09666667936585e-06	UP	4.49144518239205	3.15986651434323e-05	Inflammatory bowel disease (IBD): IFNG**
hsa03320__21	7.32562593077285e-06	DOWN	-4.48467790021276	3.25410192054898e-05	PPAR signaling pathway: ACAA1
hsa04261__66	8.05565879899256e-06	DOWN	-4.46437605367491	3.56994879323279e-05	Adrenergic signaling in cardiomyocytes: C01245
hsa04550__66	8.36672395912738e-06	UP	4.45625531505976	3.69907631040008e-05	Signaling pathways regulating pluripotency of stem cells: MYC
hsa04024__115	8.5265297689989e-06	UP	4.45219494575219	3.76088014928379e-05	cAMP signaling pathway: F2R
hsa04150__33	8.96706566710978e-06	DOWN	-4.44136729426533	3.94592889660405e-05	mTOR signaling pathway: RPS6
hsa04924__31	9.37025618176296e-06	DOWN	-4.43189309921433	4.1137176087693e-05	Renin secretion: C02135
hsa04725__18	1.06200796324044e-05	DOWN	-4.40482397049719	4.65154536813239e-05	Cholinergic synapse: ITPR1
hsa05222__34	1.10250478234431e-05	UP	4.39670323188205	4.81768950238364e-05	Small cell lung cancer: CCND1
hsa04540__14 31	1.10939599677625e-05	DOWN	-4.39534977544619	4.82535897671891e-05	Gap junction: GJA1 TJP1
hsa04724__3	1.10939599677625e-05	DOWN	-4.39534977544619	4.82535897671891e-05	Glutamatergic synapse: GRIK1
hsa04022__48	1.11632832227823e-05	DOWN	-4.39399631901033	4.83313575474838e-05	cGMP-PKG signaling pathway: SLC8A2
hsa05205__146	1.11632832227823e-05	UP	4.39399631901033	4.83313575474838e-05	Proteoglycans in cancer: PTK2
hsa04068__51	1.13737429620875e-05	DOWN	-4.38993594970276	4.9016658315969e-05	FoxO signaling pathway: BCL6
hsa04068__56	1.13737429620875e-05	DOWN	-4.38993594970276	4.9016658315969e-05	FoxO signaling pathway: BCL6*
hsa05205__422	1.15879871354419e-05	DOWN	-4.38587558039519	4.98256929690968e-05	Proteoglycans in cancer: CD63
hsa05014__32 34	1.16602539561035e-05	DOWN	-4.38452212395933	5.00219570399967e-05	Amyotrophic lateral sclerosis (ALS): NEFM PRPH
hsa04015__63	1.17329508351698e-05	DOWN	-4.38316866752348	5.0219167697686e-05	Rap1 signaling pathway: GNAI1
hsa05032__30	1.18060411159389e-05	UP	4.38181521108762	5.04171619473844e-05	Morphine addiction: ADORA1
hsa05132__48	1.20280876345936e-05	DOWN	-4.37775484178005	5.12489266789149e-05	Salmonella infection: KLC3
hsa04152__77	1.21029714430233e-05	UP	4.37640138534419	5.14513197770155e-05	AMPK signaling pathway: CCND1
hsa04530__20 22	1.22540759754763e-05	DOWN	-4.37369447247247	5.19760920043339e-05	Tight junction: ACTB MYL12B
hsa04066__50	1.2561703259046e-05	DOWN	-4.36828064672905	5.31609018552869e-05	HIF-1 signaling pathway: TF
hsa04630__33	1.29566077266282e-05	DOWN	-4.36151336454976	5.47089121760323e-05	Jak-STAT signaling pathway: RAF1
hsa04530__5 10	1.31178626887945e-05	DOWN	-4.35880645167805	5.52656143323874e-05	Tight junction: IGSF5 MAGI1
hsa05215__30	1.31992064319972e-05	UP	4.35745299524219	5.54839124960239e-05	Prostate cancer: TP53
hsa04012__48	1.34461349160219e-05	DOWN	-4.35339262593462	5.62701280784077e-05	ErbB signaling pathway: CAMK2A
hsa04917__75	1.34461349160219e-05	UP	4.35339262593462	5.62701280784077e-05	Prolactin signaling pathway: CCND1**
hsa04014__43	1.36131954051083e-05	DOWN	-4.3506857130629	5.68426537026631e-05	Ras signaling pathway: ELK1
hsa04115__55	1.4301448169357e-05	UP	4.33985806157605	5.95840822843056e-05	p53 signaling pathway: SHISA5
hsa04024__3	1.47483245086112e-05	DOWN	-4.33309077939676	6.13099596276116e-05	cAMP signaling pathway: RYR2
hsa04270__46	1.5682338236178e-05	UP	4.31955621503819	6.49055364444461e-05	Vascular smooth muscle contraction: ITPR1*
hsa04722__50	1.5682338236178e-05	UP	4.31955621503819	6.49055364444461e-05	Neurotrophin signaling pathway: RHOA
hsa04064__55	1.61702332231753e-05	DOWN	-4.3127889328589	6.66312899700578e-05	NF-kappa B signaling pathway: CXCL12
hsa05164__47	1.61702332231753e-05	UP	4.3127889328589	6.66312899700578e-05	Influenza A: CIITA
hsa04612__39	1.65709318871498e-05	UP	4.30737510711547	6.81330000349115e-05	Antigen processing and presentation: PSME3
hsa04740__42	1.67748127733876e-05	DOWN	-4.30466819424376	6.88206838454047e-05	Olfactory transduction: PDE2A
hsa04740__33	1.69810828692819e-05	DOWN	-4.30196128137204	6.95151518766462e-05	Olfactory transduction: CNGA3*
hsa04066__37	1.72950257575544e-05	UP	4.29790091206447	7.06464204314017e-05	HIF-1 signaling pathway: PDHA1
hsa04620__12	1.7400896841212e-05	DOWN	-4.29654745562862	7.09246966694952e-05	Toll-like receptor signaling pathway: NFKB1
hsa05205__69	1.79395809436815e-05	DOWN	-4.28978017344933	7.28044764431482e-05	Proteoglycans in cancer: MAPK1*
hsa05211__4	1.79395809436815e-05	UP	4.28978017344933	7.28044764431482e-05	Renal cell carcinoma: SLC2A1
hsa04919__84	1.81594722481445e-05	UP	4.28707326057762	7.35380352462575e-05	Thyroid hormone signaling pathway: TP53*
hsa05020__49	1.84941297274574e-05	UP	4.28301289127004	7.47321930277257e-05	Prion diseases: BAX
hsa05211__40	1.87204897726598e-05	UP	4.28030597839833	7.54845499631497e-05	Renal cell carcinoma: PAK4
hsa04068__42	1.97721713429799e-05	DOWN	-4.26812487047562	7.95544110352446e-05	FoxO signaling pathway: CDKN2D
hsa04670__35	2.00134014662156e-05	UP	4.2654179576039	8.03529516132886e-05	Leukocyte transendothelial migration: PTK2
hsa04151__103	2.05042953168851e-05	DOWN	-4.26000413186047	8.17995135890173e-05	PI3K-Akt signaling pathway: BCL2*
hsa05016__48	2.05042953168851e-05	UP	4.26000413186047	8.17995135890173e-05	Huntington's disease: HIP1
hsa05016__46	2.05042953168851e-05	UP	4.26000413186047	8.17995135890173e-05	Huntington's disease: HTT**
hsa04066__56	2.11340452193568e-05	DOWN	-4.25323684968119	8.41332012016343e-05	HIF-1 signaling pathway: TEK
hsa05161__188	2.12621855449666e-05	UP	4.25188339324533	8.44643692156283e-05	Hepatitis B: IFNB1
hsa04012__31	2.20466971035261e-05	DOWN	-4.24376265463019	8.73960840876065e-05	ErbB signaling pathway: BAD
hsa04150__56	2.24492103084702e-05	DOWN	-4.23970228532261	8.86177860706206e-05	mTOR signaling pathway: EIF4B
hsa04810__26 80	2.24492103084702e-05	UP	4.23970228532261	8.86177860706206e-05	Regulation of actin cytoskeleton: PFN3 ACTB
hsa04540__14 16	2.35570541412143e-05	DOWN	-4.22887463383576	9.26018927433927e-05	Gap junction: GJA1 GJA1
hsa04540__14 15	2.35570541412143e-05	DOWN	-4.22887463383576	9.26018927433927e-05	Gap junction: GJA1 GJA1*
hsa04151__98	2.36991375802227e-05	UP	4.2275211773999	9.29659280025853e-05	PI3K-Akt signaling pathway: BCL2L1*
hsa03320__10	2.39857543739673e-05	DOWN	-4.22481426452819	9.36990280014233e-05	PPAR signaling pathway: PLIN1
hsa03320__38	2.39857543739673e-05	DOWN	-4.22481426452819	9.36990280014233e-05	PPAR signaling pathway: SORBS1
hsa04530__5 11 31	2.44218708922314e-05	DOWN	-4.22075389522061	9.52047622541553e-05	Tight junction: IGSF5 TJP1 MLLT4
hsa04261__62	2.48655246794002e-05	DOWN	-4.21669352591304	9.67335835871492e-05	Adrenergic signaling in cardiomyocytes: BCL2
hsa04010__67	2.51655418196067e-05	UP	4.21398661304133	9.7698456774878e-05	MAPK signaling pathway: ELK1
hsa05168__138	2.53168385591139e-05	UP	4.21263315660547	9.80831745413918e-05	Herpes simplex infection: CHUK
hsa05168__106 134	2.577593722092e-05	UP	4.2085727872979	9.96563498726516e-05	Herpes simplex infection: SRSF8 C1QBP
hsa05164__53	2.80251011165663e-05	DOWN	-4.1896243971959	0.000108129702254678	Influenza A: MAPK14
hsa04666__23	2.81927003098252e-05	UP	4.18827094076004	0.0001085534505782	Fc gamma R-mediated phagocytosis: RPS6KB1
hsa04064__93	2.83612521062977e-05	UP	4.18691748432418	0.000108979126191684	NF-kappa B signaling pathway: PLAU
hsa05168__122	2.85307616098912e-05	UP	4.18556402788833	0.000109406736867317	Herpes simplex infection: CASP3
hsa04115__27	2.88726742815952e-05	UP	4.18285711501661	0.00011049237265808	p53 signaling pathway: THBS1
hsa04360__122	2.90450877853951e-05	DOWN	-4.18150365858076	0.00011070125750255	Axon guidance: CFL1**
hsa05210__23	2.90450877853951e-05	UP	4.18150365858076	0.00011070125750255	Colorectal cancer: CCND1
hsa05217__5	3.1191878655959e-05	DOWN	-4.16526218135047	0.000118642793511229	Basal cell carcinoma: BMP2
hsa05200__201	3.17516739503953e-05	UP	4.1612018120429	0.000120528071419783	Pathways in cancer: PDGFB
hsa05221__29	3.21301598020788e-05	DOWN	-4.15849489917118	0.000121718891669569	Acute myeloid leukemia: RPS6KB1
hsa05014__31 34	3.25129295151029e-05	DOWN	-4.15578798629947	0.000122921115812633	Amyotrophic lateral sclerosis (ALS): NEFL PRPH
hsa04024__113	3.29000287395734e-05	DOWN	-4.15308107342775	0.000124134847392888	cAMP signaling pathway: PTCH1
hsa04068__66	3.3291503578138e-05	DOWN	-4.15037416055604	0.000125360190828299	FoxO signaling pathway: BNIP3
hsa04380__20	3.3488896384533e-05	UP	4.14902070412018	0.000125851272613075	Osteoclast differentiation: MAP2K1
hsa04210__56	3.4289640666491e-05	UP	4.14360687837675	0.000128603263098476	Apoptosis: BAX
hsa04024__110	3.59460052359327e-05	DOWN	-4.1327792268899	0.00013454690007633	cAMP signaling pathway: FOS
hsa04916__7	3.68024080654258e-05	DOWN	-4.12736540114647	0.00013747857804162	Melanogenesis: TYRP1
hsa04913__35	3.70195160354893e-05	DOWN	-4.12601194471061	0.000138015219505326	Ovarian steroidogenesis: HSD17B2
hsa05030__73	3.7237839609841e-05	DOWN	-4.12465848827475	0.000138280436021524	Cocaine addiction: NFKB1
hsa05200__80	3.7237839609841e-05	UP	4.12465848827475	0.000138280436021524	Pathways in cancer: TP53
hsa05200__189	3.74573851925695e-05	UP	4.1233050318389	0.000138548084206374	Pathways in cancer: BIRC5
hsa05220__50	3.74573851925695e-05	DOWN	-4.1233050318389	0.000138548084206374	Chronic myeloid leukemia: MAPK1
hsa04921__77	4.21150633240578e-05	UP	4.09623590312175	0.000155469948891758	Oxytocin signaling pathway: KCNJ3
hsa04115__15	4.23618072165056e-05	UP	4.0948824466859	0.000156074187764341	p53 signaling pathway: TSC2
hsa04970__27	4.38713152167691e-05	DOWN	-4.08676170807075	0.000161319376305889	Salivary secretion: PRKCA
hsa03320__31	4.67721807679982e-05	DOWN	-4.07187368727632	0.000171315648466021	PPAR signaling pathway: CD36
hsa05120__19	4.67721807679982e-05	UP	4.07187368727632	0.000171315648466021	Epithelial cell signaling in Helicobacter pylori infection: CXCL1
hsa04919__25	4.73187821013837e-05	UP	4.06916677440461	0.000172980528343385	Thyroid hormone signaling pathway: MTOR
hsa05200__222	4.87119052050376e-05	UP	4.06239949222532	0.000177383081163306	Pathways in cancer: CASP9*
hsa05215__8	4.87119052050376e-05	DOWN	-4.06239949222532	0.000177383081163306	Prostate cancer: NFKBIA
hsa04210__71	4.95663499632703e-05	DOWN	-4.05833912291775	0.000180145399576373	Apoptosis: GADD45G
hsa04650__40	5.10220760903964e-05	UP	4.05157184073847	0.000185078148598175	Natural killer cell mediated cytotoxicity: TNFRSF10D
hsa05210__21	5.22157368728461e-05	UP	4.04615801499504	0.000189043101318069	Colorectal cancer: BIRC5
hsa04924__23	5.25182607062646e-05	DOWN	-4.04480455855918	0.000189772715128983	Renin secretion: ITPR1
hsa04066__43	5.59575125543547e-05	DOWN	-4.02991653776475	0.00020181221898202	HIF-1 signaling pathway: PFKL
hsa03320__20	5.82560695062643e-05	DOWN	-4.02044234271375	0.000209699529889407	PPAR signaling pathway: SCP2
hsa04742__4	5.99523370534501e-05	UP	4.01367506053447	0.000215392813237921	Taste transduction: TRPM5
hsa04064__137	6.16953013201015e-05	UP	4.00690777835518	0.000221231815229906	NF-kappa B signaling pathway: ICAM1
hsa04919__89	6.20496031880064e-05	DOWN	-4.00555432191932	0.000222078484552884	Thyroid hormone signaling pathway: CASP9
hsa04010__129	6.24058307374473e-05	UP	4.00420086548347	0.00022250579877735	MAPK signaling pathway: FOS
hsa04933__24	6.24058307374473e-05	DOWN	-4.00420086548347	0.00022250579877735	AGE-RAGE signaling pathway in diabetic complications: THBD
hsa04540__12	6.31240670283874e-05	UP	4.00149395261175	0.000224640382474128	Gap junction: C00025
hsa04390__18	6.49541725730682e-05	UP	3.99472667043247	0.000230716238685813	Hippo signaling pathway: MOB1A
hsa04270__17	6.72165532124441e-05	DOWN	-3.98660593181732	0.000237405833620644	Vascular smooth muscle contraction: ITPR1
hsa04550__101	6.72165532124441e-05	DOWN	-3.98660593181732	0.000237405833620644	Signaling pathways regulating pluripotency of stem cells: ESRRB
hsa05210__31	6.72165532124441e-05	DOWN	-3.98660593181732	0.000237405833620644	Colorectal cancer: BCL2
hsa05162__23	7.53083389630995e-05	UP	3.95953680310018	0.000264989454890756	Measles: IRF3
hsa05164__90	7.53083389630995e-05	DOWN	-3.95953680310018	0.000264989454890756	Influenza A: MAPK1
hsa04664__25	7.57361896469398e-05	DOWN	-3.95818334666432	0.000265996823077757	Fc epsilon RI signaling pathway: MAPK14
hsa05321__46	7.61663381810335e-05	UP	3.95682989022846	0.000267008487765227	Inflammatory bowel disease (IBD): IFNG*
hsa04210__74	7.79101426006514e-05	UP	3.95141606448504	0.000272106241536476	Apoptosis: BAX*
hsa05231__48	7.79101426006514e-05	DOWN	-3.95141606448504	0.000272106241536476	Choline metabolism in cancer: WAS
hsa04022__9	7.83519546921957e-05	UP	3.95006260804918	0.000272635783086362	cGMP-PKG signaling pathway: ITPR1
hsa04115__16	7.83519546921957e-05	UP	3.95006260804918	0.000272635783086362	p53 signaling pathway: PPM1D
hsa04666__50 52	7.96916462179977e-05	UP	3.94600223874161	0.000276274175726232	Fc gamma R-mediated phagocytosis: DNM2 AMPH
hsa05134__10	7.96916462179977e-05	DOWN	-3.94600223874161	0.000276274175726232	Legionellosis: NFKB1
hsa05200__146 147	8.15114344213721e-05	DOWN	-3.94058841299818	0.000281027495922492	Pathways in cancer: RARB RXRA
hsa05222__14 15	8.15114344213721e-05	DOWN	-3.94058841299818	0.000281027495922492	Small cell lung cancer: RXRA RARB
hsa05223__29 34	8.15114344213721e-05	DOWN	-3.94058841299818	0.000281027495922492	Non-small cell lung cancer: RARB RXRA
hsa04310__57	8.19727019440478e-05	UP	3.93923495656232	0.00028210019588437	Wnt signaling pathway: SIAH1
hsa04066__45	8.57511952993869e-05	DOWN	-3.92840730507546	0.00029456397800283	HIF-1 signaling pathway: ALDOA
hsa04950__15	8.91918116146569e-05	DOWN	-3.91893311002446	0.000305823748218869	Maturity onset diabetes of the young: IAPP
hsa04114__59	8.96938450755182e-05	UP	3.91757965358861	0.000306984945167393	Oocyte meiosis: REC8*
hsa05010__61	9.01985470619657e-05	UP	3.91622619715275	0.000308151036235334	Alzheimer's disease: GAPDH
hsa04064__136	9.07059308289215e-05	UP	3.91487274071689	0.000309322039977393	NF-kappa B signaling pathway: TNFSF13B*
hsa04024__114	9.32835445481363e-05	DOWN	-3.90810545853761	0.000317535833706428	cAMP signaling pathway: HHIP
hsa05220__21	9.48631557601049e-05	DOWN	-3.90404508923003	0.000322328878251785	Chronic myeloid leukemia: NFKBIA
hsa04390__96	9.80984590047306e-05	DOWN	-3.89592435061489	0.000332720224674889	Hippo signaling pathway: FGF1
hsa05161__44	9.97549087006399e-05	UP	3.89186398130732	0.000337728780988293	Hepatitis B: CXCL8
hsa04066__42	0.000101437737539789	DOWN	-3.88780361199975	0.00034280846913177	HIF-1 signaling pathway: HK1
hsa04520__4	0.000102004610101339	DOWN	-3.88645015556389	0.000344105318456762	Adherens junction: CTNND1
hsa05205__369	0.000106057243188815	UP	3.87697596051289	0.000357135412099969	Proteoglycans in cancer: HOXD10
hsa04015__95	0.000107242755067175	UP	3.87426904764118	0.000360481461129198	Rap1 signaling pathway: THBS1
hsa04020__7	0.000108440762994357	UP	3.87156213476946	0.000363857488689995	Calcium signaling pathway: ADCY1
hsa04520__9 57	0.000115898184999542	DOWN	-3.85532065753918	0.000388186612502923	Adherens junction: LEF1 CTNNB1
hsa04630__36	0.000116540995720566	UP	3.85396720110332	0.000389645072880682	Jak-STAT signaling pathway: GFAP
hsa04913__45	0.000121805869680622	DOWN	-3.84313954961646	0.000406524385665876	Ovarian steroidogenesis: ACOT2
hsa04910__32	0.000123837392936999	DOWN	-3.83907918030889	0.000412571739944364	Insulin signaling pathway: EIF4E
hsa04350__12	0.000125209440838527	DOWN	-3.83637226743717	0.000414935695477236	TGF-beta signaling pathway: ACVR2A
hsa04916__10	0.000125209440838527	DOWN	-3.83637226743717	0.000414935695477236	Melanogenesis: CAMK2A
hsa04931__140	0.000125209440838527	DOWN	-3.83637226743717	0.000414935695477236	Insulin resistance: G00369
hsa04740__16	0.000131562887596824	DOWN	-3.82419115951446	0.000434458112116751	Olfactory transduction: PRKG1
hsa05030__77	0.000131562887596824	DOWN	-3.82419115951446	0.000434458112116751	Cocaine addiction: BDNF
hsa04012__23	0.000137464274076322	DOWN	-3.8133635080276	0.000453149773665629	ErbB signaling pathway: RPS6KB1
hsa05205__238	0.000139740901854295	UP	3.80930313872003	0.000459847906452225	Proteoglycans in cancer: ITGAV*
hsa04014__38	0.000143614380339287	DOWN	-3.80253585654075	0.000471768217932727	Ras signaling pathway: MAPK8
hsa04012__40	0.000145191902200759	DOWN	-3.79982894366903	0.000476117948054494	ErbB signaling pathway: ELK1*
hsa04115__50	0.000145986768449542	UP	3.79847548723317	0.000477890484175419	p53 signaling pathway: RCHY1
hsa05200__220	0.000156700024001126	UP	3.78088055356703	0.000512068426257593	Pathways in cancer: CSF1R*
hsa04390__58	0.000157554056564604	DOWN	-3.77952709713117	0.000513965403272382	Hippo signaling pathway: SMAD7
hsa04010__131	0.000159275280003305	UP	3.77682018425946	0.000516888171202436	MAPK signaling pathway: MYC
hsa05031__11	0.000159275280003305	UP	3.77682018425946	0.000516888171202436	Amphetamine addiction: GRIN3A
hsa05031__54	0.000159275280003305	UP	3.77682018425946	0.000516888171202436	Amphetamine addiction: GRIN3A*
hsa04750__60	0.000165439442421644	DOWN	-3.76734598920846	0.000535966745362532	Inflammatory mediator regulation of TRP channels: TRPV3
hsa04261__73	0.000169979945495154	DOWN	-3.76057870702917	0.000549728601696033	Adrenergic signaling in cardiomyocytes: KCNE1
hsa05162__81	0.00017463695492971	UP	3.75381142484989	0.000563819309816021	Measles: TNFRSF10D
hsa05150__13	0.000183323374724794	DOWN	-3.74163031692717	0.000589836679979261	Staphylococcus aureus infection: C5AR1
hsa05217__19	0.000183323374724794	DOWN	-3.74163031692717	0.000589836679979261	Basal cell carcinoma: HHIP
hsa04068__14	0.000184313217723594	DOWN	-3.74027686049132	0.000592007754021595	FoxO signaling pathway: G6PC
hsa04750__51	0.000190358304855375	UP	3.73215612187617	0.000608305745228914	Inflammatory mediator regulation of TRP channels: TRPV4
hsa04750__61	0.000190358304855375	UP	3.73215612187617	0.000608305745228914	Inflammatory mediator regulation of TRP channels: TRPV4*
hsa05150__69	0.00019035858339255	UP	3.73215612187617	0.000608305745228914	Staphylococcus aureus infection: FPR2
hsa05214__23	0.00019977701673319	DOWN	-3.71997501395346	0.000636239007528244	Glioma: MAPK1
hsa05214__56	0.00019977701673319	DOWN	-3.71997501395346	0.000636239007528244	Glioma: MAPK1*
hsa04152__30	0.00020629733918337	UP	3.71185427533831	0.000654784966766134	AMPK signaling pathway: ACACA
hsa05200__217	0.00020629733918337	UP	3.71185427533831	0.000654784966766134	Pathways in cancer: E2F1*
hsa04924__30	0.000207403304320024	UP	3.71050081890246	0.000657185175071374	Renin secretion: PDE3A
hsa04210__69	0.000209631961897751	DOWN	-3.70779390603074	0.000662014212446848	Apoptosis: PTPN13
hsa05145__4 5	0.000209631961897751	UP	3.70779390603074	0.000662014212446848	Toxoplasmosis: MAP3K7 TAB1
hsa04725__53	0.000211882688552541	DOWN	-3.70508699315903	0.000667999281527221	Cholinergic synapse: CHRNA7
hsa05205__183	0.000216453637330398	UP	3.6996731674156	0.000681266975785291	Proteoglycans in cancer: VEGFA*
hsa04530__30	0.000218773469413769	UP	3.69696625454389	0.000687416971619517	Tight junction: AKT3
hsa04919__104	0.000221116629149167	DOWN	-3.69425934167217	0.000693619609634866	Thyroid hormone signaling pathway: MYC
hsa04742__23 45	0.000223483120229938	UP	3.69155242880046	0.000699874638186754	Taste transduction: PKD1L3 PKD2L1
hsa04068__55	0.000228288255814048	DOWN	-3.68613860305703	0.000713733165847914	FoxO signaling pathway: ATM
hsa04064__25	0.000239456126881739	UP	3.67395749513431	0.000747405419287022	NF-kappa B signaling pathway: NFKB2
hsa04962__22	0.000249811484128628	DOWN	-3.66312984364746	0.000778434127160353	Vasopressin-regulated water reabsorption: ARHGDIA
hsa04340__13	0.000251135041859709	DOWN	-3.6617763872116	0.000781262820619856	Hedgehog signaling pathway: GLI1*
hsa04115__23	0.00026058573784248	UP	3.6523021921606	0.000809323308109123	p53 signaling pathway: PTEN
hsa04064__114	0.000264737253431531	UP	3.64824182285303	0.000820860229699417	NF-kappa B signaling pathway: BCL2A1*
hsa05142__64	0.000268950712369206	UP	3.64418145354546	0.00083255088721868	Chagas disease (American trypanosomiasis): CASP8
hsa05222__32	0.000287945868495112	UP	3.62658651987931	0.00088988534029986	Small cell lung cancer: BIRC8
hsa04722__37	0.000289457922680852	UP	3.62523306344346	0.000893089387056355	Neurotrophin signaling pathway: NFKB1
hsa04666__29	0.000290977412742169	UP	3.6238796070076	0.000896305833676288	Fc gamma R-mediated phagocytosis: WAS
hsa05205__189	0.000294038835712037	UP	3.62117269413588	0.000904253637156986	Proteoglycans in cancer: IL12B
hsa05152__76	0.00030025240737231	UP	3.61575886839245	0.000920349548862268	Tuberculosis: TNF*
hsa05211__27	0.00030025240737231	UP	3.61575886839245	0.000920349548862268	Renal cell carcinoma: VEGFA*
hsa04931__46	0.000306588785006848	DOWN	-3.61034504264903	0.000938241574963954	Insulin resistance: PIK3R5*
hsa04024__101	0.000319638946047495	DOWN	-3.59951739116217	0.000976587934346736	cAMP signaling pathway: HCN4
hsa03320__45	0.000333207665261293	DOWN	-3.58868973967531	0.00101474425125765	PPAR signaling pathway: PDPK1
hsa04910__48	0.000333207665261293	DOWN	-3.58868973967531	0.00101474425125765	Insulin signaling pathway: PPARGC1A
hsa05205__318	0.000338433474101443	DOWN	-3.58462937036774	0.001028991096823	Proteoglycans in cancer: HSPB2
hsa04726__38	0.000340192382406924	DOWN	-3.58327591393188	0.00103266799118354	Serotonergic synapse: PLA2G4B
hsa04066__54	0.000345520557484211	UP	3.57921554462431	0.00104715020566586	HIF-1 signaling pathway: SERPINE1
hsa04115__20	0.000347313894088208	UP	3.57786208818845	0.00104920065432756	p53 signaling pathway: RRM2B
hsa04261__14 16	0.000347313894088208	UP	3.57786208818845	0.00104920065432756	Adrenergic signaling in cardiomyocytes: TNNI3 TPM1
hsa04115__34	0.000375280461059255	UP	3.5575602416506	0.00113186514659766	p53 signaling pathway: ZMAT3
hsa04530__1 5	0.000377217815028994	DOWN	-3.55620678521474	0.00113588505519147	Tight junction: IGSF5 IGSF5
hsa04650__110 111	0.000391043302572646	UP	3.54673259016374	0.00117375457753035	Natural killer cell mediated cytotoxicity: ITGAL ITGB2
hsa05132__55	0.000391043302572646	UP	3.54673259016374	0.00117375457753035	Salmonella infection: IL18
hsa04115__39	0.000393056591871773	UP	3.54537913372788	0.00117791600658224	p53 signaling pathway: BAX
hsa04010__66	0.0004137291287239	UP	3.53184456936931	0.00123592533048046	MAPK signaling pathway: TP53
hsa05162__101	0.0004137291287239	DOWN	-3.53184456936931	0.00123592533048046	Measles: CDKN1B
hsa05205__113	0.000422278995085347	UP	3.52643074362588	0.00125946385994503	Proteoglycans in cancer: TP53
hsa05200__65	0.000428799363522428	UP	3.52237037431831	0.00127688431705015	Pathways in cancer: STK4
hsa04510__47	0.000430993626839469	UP	3.52101691788245	0.00128138769751798	Focal adhesion: CCND1
hsa04713__14	0.000433198369947668	DOWN	-3.5196634614466	0.00128590795755398	Circadian entrainment: PRKCA
hsa04015__18	0.000435413638840426	UP	3.51831000501074	0.00129044515359804	Rap1 signaling pathway: CDH1
hsa04210__72	0.000437639479692069	UP	3.51695654857488	0.00129296317978207	Apoptosis: BCL2A1
hsa04920__16	0.000437639479692069	DOWN	-3.51695654857488	0.00129296317978207	Adipocytokine signaling pathway: POMC
hsa04918__14	0.000444380898470244	DOWN	-3.51289617926731	0.00131081900820344	Thyroid hormone synthesis: DUOX2
hsa05169__29	0.000451219144651124	DOWN	-3.50883580995974	0.00132890403260104	Epstein-Barr virus infection: FCER2
hsa03320__63	0.000462834867146643	DOWN	-3.50206852778045	0.00135462105197592	PPAR signaling pathway: DBI
hsa04115__29	0.000462834867146643	DOWN	-3.50206852778045	0.00135462105197592	p53 signaling pathway: IGF1
hsa04915__21	0.000462834867146643	DOWN	-3.50206852778045	0.00135462105197592	Estrogen signaling pathway: CREB3
hsa04971__39	0.000462834867146643	DOWN	-3.50206852778045	0.00135462105197592	Gastric acid secretion: EZR
hsa05130__55	0.000477141915863333	DOWN	-3.49394778916531	0.00139432295475459	Pathogenic Escherichia coli infection: ACTB
hsa04390__79	0.000484449144746402	DOWN	-3.48988741985774	0.00141347817232685	Hippo signaling pathway: SNAI2
hsa04670__86	0.000486907989962031	UP	3.48853396342188	0.00141844978781187	Leukocyte transendothelial migration: ACTB
hsa04510__42	0.000489378469995498	UP	3.48718050698602	0.00142343985312932	Focal adhesion: BIRC2
hsa04930__9	0.000496859586793897	UP	3.48312013767845	0.00144296624974611	Type II diabetes mellitus: C00238
hsa04550__22	0.000507001872488196	UP	3.47770631193502	0.00147014894815636	Signaling pathways regulating pluripotency of stem cells: SMAD2
hsa03320__26	0.000512144755719735	DOWN	-3.47499939906331	0.00148049230153443	PPAR signaling pathway: CPT2
hsa04610__44	0.000512144755719735	DOWN	-3.47499939906331	0.00148049230153443	Complement and coagulation cascades: C3
hsa04115__36	0.000519950328197204	UP	3.47093902975574	0.00150074756786873	p53 signaling pathway: EI24
hsa04530__20 62	0.000522576728984073	DOWN	-3.46958557331988	0.00150601483705686	Tight junction: ACTB SHROOM1
hsa05211__23	0.00052786666382884	UP	3.46687866044816	0.00151893026238038	Renal cell carcinoma: PDGFB
hsa04064__96	0.000533206466129896	UP	3.46417174757645	0.00152727888697877	NF-kappa B signaling pathway: BCL2A1
hsa04742__34	0.000533206466129896	UP	3.46417174757645	0.00152727888697877	Taste transduction: GRM1
hsa04961__5	0.000533206466129896	DOWN	-3.46417174757645	0.00152727888697877	Endocrine and other factor-regulated calcium reabsorption: TRPV5
hsa04068__40	0.000546776975967091	DOWN	-3.45740446539716	0.00156376550660908	FoxO signaling pathway: CCND1
hsa05161__194	0.000549529400348861	UP	3.45605100896131	0.00156924884993238	Hepatitis B: TNF*
hsa04022__51	0.000552294727134609	DOWN	-3.45469755252545	0.00157475234034284	cGMP-PKG signaling pathway: GTF2I
hsa04932__56	0.000555073011716911	UP	3.45334409608959	0.00158027604396375	Non-alcoholic fatty liver disease (NAFLD): CASP7
hsa04010__65	0.000557864309700317	UP	3.45199063965374	0.00158582002712087	MAPK signaling pathway: ELK4
hsa04550__36	0.000566316843296681	DOWN	-3.44793027034616	0.00160499147594942	Signaling pathways regulating pluripotency of stem cells: AKT3*
hsa05200__49	0.000566316843296681	DOWN	-3.44793027034616	0.00160499147594942	Pathways in cancer: CASP9
hsa04068__41	0.000572017961717965	DOWN	-3.44522335747445	0.00161627330837302	FoxO signaling pathway: CDKN2B
hsa05216__15	0.000572017961717965	UP	3.44522335747445	0.00161627330837302	Thyroid cancer: CCND1
hsa03320__57	0.000580669919050127	DOWN	-3.44116298816688	0.00163825642326605	PPAR signaling pathway: APOC3
hsa05160__8	0.000586505412537392	DOWN	-3.43845607529516	0.00165223938554387	Hepatitis C: NFKB1
hsa05016__12	0.00060133385534974	UP	3.43168879311588	0.00169147651826671	Huntington's disease: REST
hsa05160__66	0.000610397641052726	UP	3.42762842380831	0.00171440533264286	Hepatitis C: GSK3B
hsa04921__11	0.000644730510587681	UP	3.41274040301388	0.00180813228267799	Oxytocin signaling pathway: PRKACA
hsa04933__29	0.000647939146610698	UP	3.41138694657802	0.00181172270309747	AGE-RAGE signaling pathway in diabetic complications: ICAM1
hsa05205__215 216	0.000647939146610698	DOWN	-3.41138694657802	0.00181172270309747	Proteoglycans in cancer: EIF4B RPS6
hsa04015__96	0.000680852475529737	DOWN	-3.39785238221945	0.00189810356308661	Rap1 signaling pathway: PLCE1
hsa05132__68	0.000680852475529737	UP	3.39785238221945	0.00189810356308661	Salmonella infection: NOS2
hsa05031__96	0.000704809350574624	DOWN	-3.38837818716845	0.00196198039959958	Amphetamine addiction: PDYN
hsa04380__69	0.000711796687840231	UP	3.38567127429673	0.00197849996516538	Osteoclast differentiation: NFKB2
hsa04390__75	0.000744043476260781	DOWN	-3.37349016637402	0.00206203199394397	Hippo signaling pathway: NKD1
hsa05110__51	0.000744043476260781	UP	3.37349016637402	0.00206203199394397	Vibrio cholerae infection: PDIA4
hsa04650__35	0.000766289534928367	UP	3.36536942775888	0.00212055675424212	Natural killer cell mediated cytotoxicity: BID
hsa05211__31	0.000773841067002485	UP	3.36266251488716	0.00213830494837893	Renal cell carcinoma: SOS1
hsa04066__51	0.000777642686130993	UP	3.36130905845131	0.00214565434249653	HIF-1 signaling pathway: TFRC
hsa04720__4 15	0.000785297989160853	DOWN	-3.35860214557959	0.0021635995918376	Long-term potentiation: CREBBP ATF4
hsa04540__18 19	0.000793023193083458	DOWN	-3.35589523270788	0.00218168459707733	Gap junction: GJA1 GJA1***
hsa04014__26	0.000796912189321344	DOWN	-3.35454177627202	0.0021859824872041	Ras signaling pathway: PRKCA
hsa04933__19	0.000796912189321344	DOWN	-3.35454177627202	0.0021859824872041	AGE-RAGE signaling pathway in diabetic complications: TGFBR2
hsa04014__70	0.000804743335563244	UP	3.3518348634003	0.00220424595848883	Ras signaling pathway: RIN1*
hsa04360__59	0.000812645843566747	UP	3.34912795052859	0.00221619962273137	Axon guidance: MAPK1*
hsa05152__97	0.000812645843566747	UP	3.34912795052859	0.00221619962273137	Tuberculosis: IL18
hsa05205__434	0.000812645843566747	DOWN	-3.34912795052859	0.00221619962273137	Proteoglycans in cancer: CASP3
hsa04024__31	0.000816624043015279	DOWN	-3.34777449409273	0.00222060286081868	cAMP signaling pathway: C00165
hsa04024__32	0.000816624043015279	DOWN	-3.34777449409273	0.00222060286081868	cAMP signaling pathway: C01245
hsa05130__26	0.000840874846764665	UP	3.33965375547759	0.00228324253911966	Pathogenic Escherichia coli infection: CTNNB1
hsa05160__37	0.000904350619640524	UP	3.31935190893973	0.0024488073141806	Hepatitis C: STAT3
hsa05169__60	0.000904455708377506	DOWN	-3.31935190893973	0.0024488073141806	Epstein-Barr virus infection: NFKB1
hsa04390__59	0.000967789953176287	UP	3.30040351883773	0.00261651413240035	Hippo signaling pathway: SERPINE1
hsa05161__97	0.00106541433854397	DOWN	-3.27333439012059	0.00287631256052317	Hepatitis B: BCL2
hsa05205__81	0.0011122516246691	UP	3.26115328219787	0.00299845165387839	Proteoglycans in cancer: CTTN
hsa05145__35	0.00112291520262238	UP	3.25844636932616	0.00302286198528287	Toxoplasmosis: CASP3
hsa04066__61	0.0011282823641082	DOWN	-3.2570929128903	0.00303296503885453	HIF-1 signaling pathway: HMOX1
hsa04916__15	0.00113908790445145	DOWN	-3.25438600001859	0.00305763738923469	Melanogenesis: MITF*
hsa04914__23	0.00114998903495163	DOWN	-3.25167908714687	0.00308249557300158	Progesterone-mediated oocyte maturation: PRKACA
hsa05205__284	0.00117208113195075	DOWN	-3.24626526140344	0.0031327744622126	Proteoglycans in cancer: PRKCA*
hsa05217__4	0.00117208113195075	DOWN	-3.24626526140344	0.0031327744622126	Basal cell carcinoma: PTCH1
hsa04623__8	0.00118327364460378	UP	3.24355834853173	0.00315819769632174	Cytosolic DNA-sensing pathway: TBK1
hsa04020__22	0.00121168612317081	DOWN	-3.23679106635244	0.00322487602610193	Calcium signaling pathway: C00575
hsa04010__86	0.0012116883844747	UP	3.23679106635244	0.00322487602610193	MAPK signaling pathway: MAP4K2
hsa04950__31	0.00122322973932168	DOWN	-3.23408415348073	0.00325098823222834	Maturity onset diabetes of the young: NKX6-1*
hsa04621__21 30	0.00122903841386481	UP	3.23273069704487	0.00326181240063838	NOD-like receptor signaling pathway: NLRP3 PYCARD
hsa04261__15 16	0.0012348725537848	DOWN	-3.23137724060902	0.00326806412473471	Adrenergic signaling in cardiomyocytes: ACTC1 TPM1
hsa04621__33 35	0.0012348725537848	UP	3.23137724060902	0.00326806412473471	NOD-like receptor signaling pathway: NLRC4 PYCARD
hsa04024__76	0.00124073225998845	DOWN	-3.23002378417316	0.00327895346908339	cAMP signaling pathway: C00416
hsa04110__46	0.0012644287779867	UP	3.22460995842973	0.00333688437336659	Cell cycle: RB1
hsa05168__39 40	0.00127041784143546	UP	3.22325650199387	0.0033479875512724	Herpes simplex infection: POU2F3 HCFC2
hsa04722__85	0.00130690561290128	DOWN	-3.21513576337873	0.00343451139390421	Neurotrophin signaling pathway: BAX
hsa04919__11	0.00130690561290128	UP	3.21513576337873	0.00343451139390421	Thyroid hormone signaling pathway: CTNNB1
hsa04350__41	0.00131308011299899	DOWN	-3.21378230694287	0.00344591834123617	TGF-beta signaling pathway: SMAD4***
hsa04152__57	0.00133804827515224	UP	3.20836848119944	0.00349679097219896	AMPK signaling pathway: ACACA*
hsa04380__48	0.00133804827515224	UP	3.20836848119944	0.00349679097219896	Osteoclast differentiation: NFATC1
hsa05200__209	0.00133804827515224	DOWN	-3.20836848119944	0.00349679097219896	Pathways in cancer: FIGF**
hsa03320__61	0.0013763227595569	DOWN	-3.2002477425843	0.00359182009056586	PPAR signaling pathway: APOA1
hsa04210__99	0.00140239734621258	UP	3.19483391684087	0.00365479141960255	Apoptosis: BID**
hsa05200__215	0.00141560475205617	DOWN	-3.19212700396916	0.00368410156386918	Pathways in cancer: CSF1R
hsa04915__58	0.00142892675058522	DOWN	-3.18942009109744	0.00371362844308387	Estrogen signaling pathway: CREB3***
hsa04340__46	0.00144912657086174	DOWN	-3.18535972178987	0.00376092379371438	Hedgehog signaling pathway: PRKACA
hsa05200__200	0.0014695892905439	UP	3.1812993524823	0.00380877003714758	Pathways in cancer: FIGF
hsa04014__30	0.00149031798950304	DOWN	-3.17723898317473	0.00385717286814905	Ras signaling pathway: C01245
hsa05161__69	0.00150428642345009	UP	3.17453207030301	0.00388796999953608	Hepatitis B: SMAD4
hsa05031__10	0.00153258580101705	DOWN	-3.16911824455959	0.00395024515790265	Amphetamine addiction: CACNA1C
hsa05031__53	0.00153258580101705	DOWN	-3.16911824455959	0.00395024515790265	Amphetamine addiction: CACNA1C*
hsa05161__30	0.00156864943584704	DOWN	-3.1623509623803	0.00403766067117342	Hepatitis B: MYC
hsa04919__21 53	0.00165075611264074	DOWN	-3.14746294158587	0.0042431884208645	Thyroid hormone signaling pathway: THRA C02465
hsa04012__35	0.00167382532025904	DOWN	-3.1434025722783	0.00429660898465401	ErbB signaling pathway: CBLC
hsa05200__202	0.00168936917269671	UP	3.14069565940658	0.00433059300886373	Pathways in cancer: FIGF*
hsa04024__116	0.00169719079127011	DOWN	-3.13934220297073	0.00434471593569009	cAMP signaling pathway: ACOX1
hsa04923__43	0.00172881151337206	DOWN	-3.1339283772273	0.0044196419505117	Regulation of lipolysis in adipocytes: C00219
hsa04922__51	0.00175288160303906	DOWN	-3.12986800791973	0.00447508767949781	Glucagon signaling pathway: G6PC
hsa04610__57	0.00176909909981754	UP	3.12716109504801	0.00451036256249276	Complement and coagulation cascades: PLAUR
hsa04115__37	0.00179368410985471	UP	3.12310072574044	0.00456684612793631	p53 signaling pathway: FAS
hsa05164__19	0.00181858279723112	DOWN	-3.11904035643287	0.0046239743924185	Influenza A: NFKB1
hsa04390__90	0.00191262000679335	UP	3.10415233563844	0.00485650404427663	Hippo signaling pathway: BBC3
hsa05221__13	0.00193903051380349	DOWN	-3.10009196633087	0.00491692083054894	Acute myeloid leukemia: NFKB1
hsa04340__33	0.00194790815641272	DOWN	-3.09873850989501	0.00492613650861306	Hedgehog signaling pathway: HHIP*
hsa04670__10	0.00194790815641272	UP	3.09873850989501	0.00492613650861306	Leukocyte transendothelial migration: BCAR1
hsa04066__29	0.00197476546356294	DOWN	-3.09467814058744	0.0049739736005828	HIF-1 signaling pathway: LDHA
hsa04370__39	0.00197476546356294	UP	3.09467814058744	0.0049739736005828	VEGF signaling pathway: RAC1
hsa04370__23	0.00197476546356294	UP	3.09467814058744	0.0049739736005828	VEGF signaling pathway: PTK2
hsa04370__36	0.00198379316170665	UP	3.09332468415158	0.00499002322737188	VEGF signaling pathway: NOS3
hsa04919__39	0.00199285872685689	DOWN	-3.09197122771573	0.00500612506385573	Thyroid hormone signaling pathway: ESR1
hsa05215__35	0.00202028404821218	DOWN	-3.08791085840815	0.00506824262562174	Prostate cancer: CASP9
hsa04915__66	0.0020667636154217	DOWN	-3.08114357622887	0.0051779317778365	Estrogen signaling pathway: AKT3*
hsa04360__6	0.00210465133994837	UP	3.07572975048544	0.0052658320476205	Axon guidance: MAPK1
hsa04022__59	0.00211422227986928	UP	3.07437629404958	0.00527572863728338	cGMP-PKG signaling pathway: NPPB
hsa04921__60	0.00211422227986928	DOWN	-3.07437629404958	0.00527572863728338	Oxytocin signaling pathway: ELK1
hsa05132__41	0.00213348328346145	DOWN	-3.07166938117787	0.00531673088809558	Salmonella infection: ACTB*
hsa04115__17	0.00214317508974975	UP	3.07031592474201	0.00533380926309904	p53 signaling pathway: TP73
hsa04910__24	0.00215290652016515	DOWN	-3.06896246830615	0.00535094094099249	Insulin signaling pathway: ACACA
hsa05160__7	0.00216267844720063	UP	3.0676090118703	0.00536812787620869	Hepatitis C: IRF3
hsa05216__14	0.00217249102140469	DOWN	-3.06625555543444	0.00538537022324462	Thyroid cancer: MAPK1*
hsa05160__70	0.00219223871589887	DOWN	-3.06354864256273	0.0054271627762503	Hepatitis C: CDKN1A
hsa05231__17	0.0022626583893607	UP	3.05407444751173	0.00559412514948521	Choline metabolism in cancer: SLC44A3
hsa04932__97	0.00227288582092948	UP	3.05272099107587	0.00561202688242641	Non-alcoholic fatty liver disease (NAFLD): TNF*
hsa04068__13	0.0022934678452297	DOWN	-3.05001407820415	0.00565541480470683	FoxO signaling pathway: PCK1
hsa04066__44	0.00233514493345137	DOWN	-3.04460025246073	0.00575063870243136	HIF-1 signaling pathway: GAPDH
hsa05164__65 66	0.00234567201013177	UP	3.04324679602487	0.00576900223434241	Influenza A: DNAJC3 HSPA1A
hsa04152__56	0.00236685664248881	UP	3.04053988315315	0.00579833589470206	AMPK signaling pathway: FASN
hsa04670__28 41 49	0.00236685664248881	UP	3.04053988315315	0.00579833589470206	Leukocyte transendothelial migration: ACTB CTNNA1 CTNNB1
hsa05205__233 234	0.00236685664248881	DOWN	-3.04053988315315	0.00579833589470206	Proteoglycans in cancer: ITGA2 C00925
hsa04330__19	0.00240975231534888	UP	3.03512605740972	0.00589573515695382	Notch signaling pathway: DTX2
hsa04620__48	0.00246437228181175	UP	3.02835877523044	0.00602152863137097	Toll-like receptor signaling pathway: CD80
hsa04923__52 53	0.00249768565334306	DOWN	-3.02429840592287	0.00609500174367742	Regulation of lipolysis in adipocytes: PNPLA2 ABHD5*
hsa04723__46	0.00252012290578402	UP	3.02159149305115	0.00613382246109868	Retrograde endocannabinoid signaling: ADCY1
hsa05200__185	0.00252012290578402	DOWN	-3.02159149305115	0.00613382246109868	Pathways in cancer: HHIP
hsa04360__58	0.00255412463483114	UP	3.01753112374358	0.00620853840730624	Axon guidance: PLXNC1
hsa04976__16	0.002694368333314	DOWN	-3.0012896465133	0.00654097945516409	Bile secretion: CFTR
hsa04650__15	0.00279173629757001	UP	2.99046199502644	0.00675988724630676	Natural killer cell mediated cytotoxicity: TNF
hsa04933__58	0.00279173629757001	DOWN	-2.99046199502644	0.00675988724630676	AGE-RAGE signaling pathway in diabetic complications: CCL2
hsa04922__78	0.00280413065406327	DOWN	-2.98910853859058	0.00678116023035377	Glucagon signaling pathway: ACACA
hsa04071__59 60	0.00284161584560719	DOWN	-2.98504816928301	0.0068629770872698	Sphingolipid signaling pathway: TP53 BCL2
hsa04010__57	0.002854212220971	UP	2.98369471284715	0.00688455040205969	MAPK signaling pathway: NLK
hsa04015__92	0.00299617235889536	UP	2.96880669205272	0.00721770238764664	Rap1 signaling pathway: C00076*
hsa04071__65	0.0030359961677325	UP	2.96474632274515	0.00729493196824728	Sphingolipid signaling pathway: BAX*
hsa05169__45	0.0030359961677325	DOWN	-2.96474632274515	0.00729493196824728	Epstein-Barr virus infection: RB1
hsa05161__227	0.00310343679688538	UP	2.95797904056587	0.00743795630273933	Hepatitis B: MYD88*
hsa05162__13	0.00310343679688538	UP	2.95797904056587	0.00743795630273933	Measles: IRF7
hsa04610__58	0.00315836969373318	UP	2.95256521482244	0.00755035197776672	Complement and coagulation cascades: F2RL2
hsa05134__71	0.00315836969373318	UP	2.95256521482244	0.00755035197776672	Legionellosis: CXCL8
hsa05134__73	0.00318616720852236	UP	2.94985830195072	0.00760712602898795	Legionellosis: CXCL1
hsa05120__52	0.00325663920391223	UP	2.94309101977144	0.00776551404080087	Epithelial cell signaling in Helicobacter pylori infection: LYN
hsa04390__60	0.00329960110760927	DOWN	-2.93903065046386	0.00785798540075769	Hippo signaling pathway: CTGF*
hsa04919__49	0.00331402572690765	DOWN	-2.93767719402801	0.00788234726691072	Thyroid hormone signaling pathway: ACTB
hsa04261__15 17	0.00340186026279451	DOWN	-2.92955645541286	0.00808103088974828	Adrenergic signaling in cardiomyocytes: ACTC1 MYH6
hsa04380__16	0.0035069966989291	UP	2.92008226036186	0.00832026110768659	Osteoclast differentiation: NFKB1
hsa04710__5	0.00352225520660783	DOWN	-2.91872880392601	0.00833541251034775	Circadian rhythm: RORA
hsa05211__42	0.00352225520660783	UP	2.91872880392601	0.00833541251034775	Renal cell carcinoma: SLC2A1*
hsa05142__44	0.00356839386511652	DOWN	-2.91466843461844	0.00842338200069591	Chagas disease (American trypanosomiasis): PLCB1
hsa05150__48	0.00356839386511652	DOWN	-2.91466843461844	0.00842338200069591	Staphylococcus aureus infection: C3AR1
hsa04211__56	0.00363076730148853	DOWN	-2.90925460887501	0.00855986419008401	Longevity regulating pathway - mammal: CAT
hsa04930__26	0.00366232438557155	DOWN	-2.90654769600329	0.00862344300813152	Type II diabetes mellitus: INS*
hsa04115__54	0.00369413067444742	UP	2.90384078313158	0.00868744873252404	p53 signaling pathway: PERP
hsa05020__52	0.00371012781187523	DOWN	-2.90248732669572	0.00871416269814195	Prion diseases: FYN
hsa04668__138	0.00392389927071291	UP	2.88489239302958	0.00920475247149757	TNF signaling pathway: NFKB1*
hsa04360__123	0.00395776243166722	DOWN	-2.88218548015786	0.00927261297893105	Axon guidance: ENAH
hsa04742__46	0.00400904770510589	DOWN	-2.87812511085029	0.00938107177819921	Taste transduction: P2RY1
hsa04630__35	0.00409588502127338	DOWN	-2.87135782867101	0.00957234820270234	Jak-STAT signaling pathway: MTOR
hsa04924__52	0.00413109235460184	UP	2.86865091579929	0.009630673119475	Renin secretion: KCNJ2
hsa05223__37	0.00413109235460184	DOWN	-2.86865091579929	0.009630673119475	Non-small cell lung cancer: CCND1*
hsa04742__27	0.00420233206959097	DOWN	-2.86323709005586	0.00978461209264119	Taste transduction: CALHM1
hsa04114__80	0.00422031525454792	UP	2.86188363362001	0.00981432223180142	Oocyte meiosis: CDC25C*
hsa04810__29	0.00429294812529749	UP	2.85646980787658	0.00997088940350308	Regulation of actin cytoskeleton: ACTN4
hsa04151__96	0.00438533244799843	DOWN	-2.84970252569729	0.0101728884812211	PI3K-Akt signaling pathway: BCL2
hsa04210__75	0.00442278804081432	UP	2.84699561282558	0.010247125436116	Apoptosis: BAK1*
hsa04917__37	0.00444162435232389	UP	2.84564215638972	0.0102780937906608	Prolactin signaling pathway: TNFSF11
hsa04922__36	0.00446053333355135	DOWN	-2.84428869995386	0.010309153916043	Glucagon signaling pathway: GYS1
hsa04932__31 133	0.00449856237238612	DOWN	-2.84158178708215	0.0103842735844146	Non-alcoholic fatty liver disease (NAFLD): PPARA RXRA
hsa04730__30	0.00453690087753559	DOWN	-2.83887487421043	0.0104599223912753	Long-term depression: C00025*
hsa04062__25	0.00461445090638324	UP	2.833461048467	0.0106256780062428	Chemokine signaling pathway: ROCK1
hsa04727__35	0.00465367434626367	DOWN	-2.83075413559529	0.0107028813912233	GABAergic synapse: PRKACA
hsa04919__29	0.00471307570606586	DOWN	-2.82669376628772	0.0108262460289704	Thyroid hormone signaling pathway: HIF1A
hsa05221__27	0.00477316260172435	DOWN	-2.82263339698015	0.0109508822083517	Acute myeloid leukemia: PIM2
hsa04211__39	0.00479334510085776	UP	2.82127994054429	0.0109837749323314	Longevity regulating pathway - mammal: TP53*
hsa04666__20	0.00483394194278112	DOWN	-2.81857302767258	0.0110633092697756	Fc gamma R-mediated phagocytosis: PLA2G4B
hsa04670__45	0.00497849248631887	UP	2.80909883262158	0.0113802766201863	Leukocyte transendothelial migration: PXN
hsa04621__21 31 41	0.004999458632415	UP	2.80774537618572	0.0114004645270725	NOD-like receptor signaling pathway: NLRP3 CARD8 CASP1
hsa05321__55	0.004999458632415	DOWN	-2.80774537618572	0.0114004645270725	Inflammatory bowel disease (IBD): IL4*
hsa04724__5 71	0.00523541217612106	UP	2.79285735539129	0.0119240478532503	Glutamatergic synapse: GRIN3A DLG4
hsa04925__33	0.0053014860074419	DOWN	-2.78879698608372	0.0120599179273406	Aldosterone synthesis and secretion: CYP11B2
hsa05034__99	0.00541328441967829	DOWN	-2.78202970390443	0.012284494474125	Alcoholism: PDYN
hsa05223__24	0.00541328441967829	UP	2.78202970390443	0.012284494474125	Non-small cell lung cancer: STK4
hsa04913__19	0.00552720704439462	DOWN	-2.77526242172515	0.0125278914793938	Ovarian steroidogenesis: STAR
hsa05210__39	0.00555024955061231	DOWN	-2.77390896528929	0.0125649625368681	Colorectal cancer: BAD
hsa05145__13	0.00559659480050654	UP	2.77120205241757	0.0126546349339973	Toxoplasmosis: GNAI1
hsa04068__50	0.00561989811157758	DOWN	-2.76984859598172	0.0126768169887806	FoxO signaling pathway: TNFSF10
hsa04932__28	0.00561989811157758	UP	2.76984859598172	0.0126768169887806	Non-alcoholic fatty liver disease (NAFLD): GSK3A
hsa05200__187	0.00566676753005479	DOWN	-2.76714168311	0.0127672136558429	Pathways in cancer: WNT16*
hsa04310__22	0.00578548582497109	UP	2.76037440093072	0.0130035058470141	Wnt signaling pathway: ROCK2
hsa05205__270	0.00578548743379657	DOWN	-2.76037440093072	0.0130035058470141	Proteoglycans in cancer: MAPK1****
hsa04540__16 17	0.00583359999833611	DOWN	-2.757667488059	0.0130959789687856	Gap junction: GJA1 GJA1**
hsa05321__19	0.00585779128595734	UP	2.75631403162315	0.0131345940648136	Inflammatory bowel disease (IBD): TNF
hsa04310__16	0.00590644533368258	DOWN	-2.75360711875143	0.0132121556928447	Wnt signaling pathway: CAMK2A
hsa04550__62 63	0.00590644533368258	UP	2.75360711875143	0.0132121556928447	Signaling pathways regulating pluripotency of stem cells: SMAD2 SMAD4
hsa04012__57	0.00598010949465807	DOWN	-2.74954674944386	0.0133610294179102	ErbB signaling pathway: ABL1
hsa05134__68	0.006155221778521	UP	2.74007255439286	0.0137196461706299	Legionellosis: TNF
hsa05166__89 90	0.006155221778521	DOWN	-2.74007255439286	0.0137196461706299	HTLV-I infection: CHUK IKBKG
hsa05161__32	0.00620609500203258	DOWN	-2.73736564152115	0.0138166498919659	Hepatitis B: STAT3
hsa04022__66	0.00630897868395855	UP	2.73195181577772	0.0140290780439741	cGMP-PKG signaling pathway: PDE3A
hsa05140__21	0.00654610062019269	UP	2.719770707855	0.0145297804908835	Leishmaniasis: NFKB1
hsa05020__24	0.00657281182397604	DOWN	-2.71841725141914	0.0145297804908835	Prion diseases: PRNP*
hsa05020__26	0.00657281182397604	DOWN	-2.71841725141914	0.0145297804908835	Prion diseases: PRNP**
hsa05020__25 8	0.00657281182397604	DOWN	-2.71841725141914	0.0145297804908835	Prion diseases: PRNP PRNP*
hsa05020__10 34	0.00657281182397604	DOWN	-2.71841725141914	0.0145297804908835	Prion diseases: PRNP PRNP***
hsa04022__57	0.0065998707402796	DOWN	-2.71706379498329	0.0145553487335509	cGMP-PKG signaling pathway: C00144
hsa04064__52	0.0065998707402796	UP	2.71706379498329	0.0145553487335509	NF-kappa B signaling pathway: TRAF1
hsa04390__94	0.00679120782252548	DOWN	-2.70758959993229	0.0149422476563529	Hippo signaling pathway: GLI2
hsa04530__20 37	0.00679120782252548	DOWN	-2.70758959993229	0.0149422476563529	Tight junction: ACTB TJP3
hsa04920__40	0.00684678367533416	DOWN	-2.70488268706057	0.0150469082174888	Adipocytokine signaling pathway: PPARGC1A
hsa05160__12 13 14	0.00690276783851324	DOWN	-2.70217577418886	0.0151522205240261	Hepatitis C: IKBKG CHUK IKBKB
hsa05216__12	0.00692010267542782	UP	2.700822317753	0.0151725471728458	Thyroid cancer: CDH1
hsa04210__57	0.00698751532692357	UP	2.69811540488129	0.0153024956868175	Apoptosis: BAK1
hsa04340__49	0.00701597145527255	UP	2.69676194844543	0.0153469270831864	Hedgehog signaling pathway: CCND1
hsa04972__42	0.00707319612088694	DOWN	-2.69405503557372	0.0154541110594727	Pancreatic secretion: CFTR
hsa04727__17 37	0.00730630857972057	DOWN	-2.68322738408686	0.0159448941013879	GABAergic synapse: GABRA1 GPHN
hsa05221__5	0.00733592716840578	DOWN	-2.681873927651	0.0159909595701096	Acute myeloid leukemia: SPI1
hsa04010__64	0.00739548771553723	UP	2.67916701477929	0.0161021105648835	MAPK signaling pathway: DDIT3
hsa03320__47	0.00751591174844114	DOWN	-2.67375318903586	0.0163264718789837	PPAR signaling pathway: PLTP
hsa04110__96 97	0.00751591174844114	UP	2.67375318903586	0.0163264718789837	Cell cycle: TFDP1 E2F4
hsa04350__44 45	0.00760738055183155	DOWN	-2.66969281972829	0.0165060832065721	TGF-beta signaling pathway: TGFBR2 TGFBR1
hsa04024__92	0.00763809117289919	UP	2.66833936329243	0.0165536024381518	cAMP signaling pathway: GRIN3A
hsa04724__52	0.00769984600945921	DOWN	-2.66563245042071	0.0166682150366058	Glutamatergic synapse: CACNA1A
hsa05010__51	0.00840927548325398	UP	2.63585640883186	0.0181830018792109	Alzheimer's disease: ATF6
hsa04919__42	0.00854436947023089	UP	2.63044258308843	0.018453873832832	Thyroid hormone signaling pathway: SLC2A1
hsa04530__4 53	0.0087854593385575	UP	2.62096838803743	0.0189527877119972	Tight junction: OCLN OCLN
hsa05162__105	0.00882039243919737	UP	2.61961493160157	0.0190063272858393	Measles: GSK3B
hsa03320__60	0.00889063114915957	DOWN	-2.61690801872986	0.0191138397360078	PPAR signaling pathway: CYP27A1
hsa05132__8	0.00889063114915957	DOWN	-2.61690801872986	0.0191138397360078	Salmonella infection: TJP1
hsa04620__66	0.00896136904857144	UP	2.61420110585814	0.019243899934018	Toll-like receptor signaling pathway: CASP8
hsa04724__68	0.00903260916318848	DOWN	-2.61149419298643	0.0193747404310858	Glutamatergic synapse: MAPK1
hsa04370__14	0.00910435453286213	UP	2.60878728011471	0.0195063650709783	VEGF signaling pathway: PTGS2
hsa05200__129 130	0.00924937326746198	UP	2.60337345437128	0.0197719822179307	Pathways in cancer: CTBP1 HDAC1
hsa05220__12 13	0.00924937326746198	UP	2.60337345437128	0.0197719822179307	Chronic myeloid leukemia: HDAC1 CTBP1
hsa04931__67	0.00928594620610913	UP	2.60201999793543	0.0198051047418609	Insulin resistance: IKBKB**
hsa04010__68	0.00928594852452341	UP	2.60201999793543	0.0198051047418609	MAPK signaling pathway: ATF2
hsa04390__14	0.00932265278286634	DOWN	-2.60066654149957	0.0198608441938842	Hippo signaling pathway: AREG
hsa04610__7	0.00935948643000593	DOWN	-2.59931308506371	0.0199167327315755	Complement and coagulation cascades: C00290
hsa05200__216	0.00954560912312464	DOWN	-2.59254580288443	0.0202898184868226	Pathways in cancer: IL6
hsa04360__21	0.00958322729083959	UP	2.59119234644857	0.0203467616717374	Axon guidance: PAK4
hsa04360__31	0.00992778403858332	UP	2.57901123852586	0.0210545216800204	Axon guidance: CDC42*
hsa04530__4 45	0.00996674133878223	UP	2.57765778209	0.0211133111336774	Tight junction: OCLN TJP2
hsa04510__26 4 5	0.010005832299201	UP	2.57630432565414	0.0211246780902417	Focal adhesion: ACTN4 ITGB1 ITGA11
hsa04066__46	0.0100058347526956	DOWN	-2.57630432565414	0.0211246780902417	HIF-1 signaling pathway: ENO1
hsa04360__11	0.0100058347526956	DOWN	-2.57630432565414	0.0211246780902417	Axon guidance: NFATC2
hsa04210__106	0.0100844290693494	DOWN	-2.57359741278243	0.0212428776443744	Apoptosis: TUBA1B
hsa04550__60	0.0100844315374039	DOWN	-2.57359741278243	0.0212428776443744	Signaling pathways regulating pluripotency of stem cells: MAPK14
hsa05205__140	0.010444961922162	UP	2.56141630485971	0.021977697034426	Proteoglycans in cancer: MAPK1***
hsa04921__48	0.0105266204116876	UP	2.558709391988	0.0221247424536476	Oxytocin signaling pathway: PRKAG2
hsa04064__2	0.0105676622216343	UP	2.55735593555214	0.0221614255741639	NF-kappa B signaling pathway: BCL2L1
hsa04115__21	0.0105676622216343	UP	2.55735593555214	0.0221614255741639	p53 signaling pathway: DDB2
hsa04612__17 28	0.010858961757038	UP	2.54788174050114	0.0227469221198153	Antigen processing and presentation: CD4 HLA-DMA
hsa04910__57	0.0109011534282732	DOWN	-2.54652828406528	0.0227845019930203	Insulin signaling pathway: GCK
hsa04961__12	0.0109011534282732	DOWN	-2.54652828406528	0.0227845019930203	Endocrine and other factor-regulated calcium reabsorption: SLC8A1
hsa05321__83	0.0109859740872047	UP	2.54382137119357	0.0229362725665084	Inflammatory bowel disease (IBD): IL2
hsa05205__319	0.011243965301515	UP	2.53570063257843	0.023448846616589	Proteoglycans in cancer: KDR
hsa05205__103	0.0114630531080114	UP	2.52893335039914	0.0238792425609239	Proteoglycans in cancer: CCND1
hsa04914__42	0.0115963170314161	DOWN	-2.52487298109157	0.0241300993377971	Progesterone-mediated oocyte maturation: ARAF
hsa04510__6 4 5	0.0116410318369989	UP	2.52351952465571	0.0241429574899462	Focal adhesion: FLNA ITGB1 ITGA11
hsa04211__42	0.0116410428344285	DOWN	-2.52351952465571	0.0241429574899462	Longevity regulating pathway - mammal: PPARGC1A
hsa04916__9	0.0116410428344285	DOWN	-2.52351952465571	0.0241429574899462	Melanogenesis: PRKACA
hsa05164__31 32 33	0.0117309399946713	UP	2.520812611784	0.0242758394594715	Influenza A: NLRP3 PYCARD CASP1
hsa04910__43	0.0117309538207558	DOWN	-2.520812611784	0.0242758394594715	Insulin signaling pathway: G6PC
hsa04520__17	0.0121898116316087	UP	2.50727804742542	0.0251976414255147	Adherens junction: SNAI1
hsa04931__124	0.0125682765365239	DOWN	-2.49645039593857	0.0259514193539872	Insulin resistance: FOXO1*
hsa04064__130	0.012907929224385	UP	2.48697620088757	0.0266234895857512	NF-kappa B signaling pathway: TNF*
hsa04750__53	0.0131056409899774	UP	2.48156237514414	0.0270016441010608	Inflammatory mediator regulation of TRP channels: TRPM8
hsa04750__62	0.0131554643939511	UP	2.48020891870828	0.0270154723542381	Inflammatory mediator regulation of TRP channels: TRPM8*
hsa04933__30	0.0131554854731921	UP	2.48020891870828	0.0270154723542381	AGE-RAGE signaling pathway in diabetic complications: CXCL8
hsa05161__48	0.0131554854731921	UP	2.48020891870828	0.0270154723542381	Hepatitis B: STAT1
hsa05140__16	0.013205497512413	UP	2.47885546227242	0.0270885696788473	Leishmaniasis: STAT1
hsa04068__53	0.0134072306704685	DOWN	-2.473441636529	0.0274723952342533	FoxO signaling pathway: SOD2
hsa04913__40	0.0134580875790197	DOWN	-2.47208818009314	0.0275465648812397	Ovarian steroidogenesis: HSD17B1
hsa05032__13	0.013560313068773	DOWN	-2.46938126722142	0.0277256020198308	Morphine addiction: PRKACA
hsa04726__41	0.0136632239745227	DOWN	-2.46667435434971	0.0278753505408559	Serotonergic synapse: HTR3C
hsa04742__57	0.0136632239745227	DOWN	-2.46667435434971	0.0278753505408559	Taste transduction: HTR3C
hsa04151__25	0.0137668241328238	DOWN	-2.46396744147799	0.0280258532454777	PI3K-Akt signaling pathway: CDKN1B
hsa04520__18	0.0137668241328238	DOWN	-2.46396744147799	0.0280258532454777	Adherens junction: SNAI2
hsa04213__2	0.0138188838848588	DOWN	-2.46261398504214	0.0280710084536754	Longevity regulating pathway - multiple species: RPS6KB1
hsa04919__103	0.0138188838848588	DOWN	-2.46261398504214	0.0280710084536754	Thyroid hormone signaling pathway: CCND1
hsa04925__34	0.0140288653263447	DOWN	-2.45720015929871	0.0284667796416866	Aldosterone synthesis and secretion: STAR
hsa04740__39	0.0141349083062786	DOWN	-2.45449324642699	0.0286510169444417	Olfactory transduction: PRKG1*
hsa04933__65	0.0145116498555472	UP	2.44501905137599	0.0293829634467383	AGE-RAGE signaling pathway in diabetic complications: COL1A1
hsa04360__96	0.0146209040214982	DOWN	-2.44231213850428	0.0295723128701777	Axon guidance: GSK3B
hsa04922__59	0.0146758025367891	DOWN	-2.44095868206842	0.0296514332974482	Glucagon signaling pathway: CPT1C
hsa03320__33	0.0148972177929409	DOWN	-2.43554485632499	0.0300664578227024	PPAR signaling pathway: CYP7A1
hsa04810__30	0.015234859517549	UP	2.42742411770985	0.0307149152719684	Regulation of actin cytoskeleton: VCL*
hsa04310__20	0.0154636804559342	DOWN	-2.42201029196642	0.0311428248410508	Wnt signaling pathway: MAPK8
hsa04660__26	0.0155213561698835	UP	2.42065683553057	0.0311921157681403	T cell receptor signaling pathway: GRB2
hsa05010__37	0.0155213561698835	DOWN	-2.42065683553057	0.0311921157681403	Alzheimer's disease: MAPT
hsa04910__18	0.0156372757635439	DOWN	-2.41794992265885	0.0313914969654905	Insulin signaling pathway: LIPE
hsa05162__27 28	0.0162283715046402	UP	2.40441535830028	0.0325433405093052	Measles: STAT1 IRF9
hsa04062__40	0.0162885474492913	DOWN	-2.40306190186442	0.0326291904661177	Chemokine signaling pathway: PRKACA
hsa04931__137	0.0165923774628664	DOWN	-2.39629461968514	0.0331671034603468	Insulin resistance: MLXIP*
hsa05222__19	0.0165923774628664	DOWN	-2.39629461968514	0.0331671034603468	Small cell lung cancer: CASP9
hsa04664__30	0.0166537372288579	DOWN	-2.39494116324928	0.0332190788248663	Fc epsilon RI signaling pathway: PRKCA
hsa05162__20	0.0166537372288579	UP	2.39494116324928	0.0332190788248663	Measles: NFKB1
hsa05161__92	0.0167152961556608	DOWN	-2.39358770681342	0.03330651270041	Hepatitis B: NFKBIA
hsa05200__218	0.0168390136259044	UP	2.39088079394171	0.0335174858083414	Pathways in cancer: CSF3R*
hsa04014__79	0.0170260969023098	UP	2.38682042463414	0.0338540064332699	Ras signaling pathway: RAC1**
hsa04024__12	0.0175983334811138	DOWN	-2.37463931671142	0.0349548293985337	cAMP signaling pathway: SLC9A1
hsa04668__111	0.0176629443752141	UP	2.37328586027556	0.0350461166642315	TNF signaling pathway: BAG4
hsa04064__53	0.0178580261363872	UP	2.36922549096799	0.0353585153954389	NF-kappa B signaling pathway: CXCL8
hsa04390__89	0.0178580261363872	DOWN	-2.36922549096799	0.0353585153954389	Hippo signaling pathway: ID2
hsa04933__27	0.0179891270482945	UP	2.36651857809628	0.0355805997092057	AGE-RAGE signaling pathway in diabetic complications: TNF
hsa04919__27	0.0184546423662367	DOWN	-2.35704438304528	0.0364629579454876	Thyroid hormone signaling pathway: GATA4
hsa05205__304	0.0185895685984177	DOWN	-2.35433747017356	0.0366909657525493	Proteoglycans in cancer: MAPK1*****
hsa05200__5	0.0186573548253291	DOWN	-2.35298401373771	0.0367475573551292	Pathways in cancer: CASP3*
hsa05210__7	0.0186573548253291	DOWN	-2.35298401373771	0.0367475573551292	Colorectal cancer: CASP3*
hsa04151__101	0.0187935763173858	UP	2.35027710086599	0.0369384203978745	PI3K-Akt signaling pathway: PKN3
hsa05030__80 81	0.0187935763173858	DOWN	-2.35027710086599	0.0369384203978745	Cocaine addiction: GRIN3A DLG4
hsa04920__5	0.01899953963093	DOWN	-2.34621673155842	0.0373042162659535	Adipocytokine signaling pathway: NFKBIA
hsa04360__40 139	0.019558452567969	DOWN	-2.33538908007156	0.0383615160492836	Axon guidance: UNC5D DCC
hsa05020__46	0.0196293167249826	DOWN	-2.33403562363571	0.0384603609241317	Prion diseases: PRKACA
hsa04520__34	0.0197003606047722	DOWN	-2.33268216719985	0.0385193143129308	Adherens junction: RHOA
hsa04919__102	0.0197004050317863	DOWN	-2.33268216719985	0.0385193143129308	Thyroid hormone signaling pathway: BMP4
hsa04071__1	0.0200592290907982	DOWN	-2.32591488502056	0.0391801366544801	Sphingolipid signaling pathway: MAPK1
hsa04068__46	0.0201316744772795	DOWN	-2.32456142858471	0.0392400584468965	FoxO signaling pathway: PLK4
hsa04072__27	0.0201316744772795	UP	2.32456142858471	0.0392400584468965	Phospholipase D signaling pathway: C01245
hsa04152__103	0.0202043480832309	DOWN	-2.32320797214885	0.0393409016045501	AMPK signaling pathway: ULK1
hsa04213__13	0.0204973364247363	DOWN	-2.31779414640542	0.0398288470962559	Longevity regulating pathway - multiple species: RPS6KB1*
hsa04923__38	0.0204973364247363	DOWN	-2.31779414640542	0.0398288470962559	Regulation of lipolysis in adipocytes: PDE3B
hsa04621__43	0.0206452151803021	UP	2.31508723353371	0.0400747513675493	NOD-like receptor signaling pathway: MAPK1
hsa04115__58	0.0208687773346211	UP	2.31102686422613	0.0404251882595392	p53 signaling pathway: CASP3
hsa04662__24	0.0208687773346211	UP	2.31102686422613	0.0404251882595392	B cell receptor signaling pathway: FOS
hsa05205__337	0.0210189883747451	DOWN	-2.30831995135442	0.0406742318806859	Proteoglycans in cancer: CTNNB1**
hsa04912__20	0.0210944465622644	DOWN	-2.30696649491856	0.0407782562659411	GnRH signaling pathway: PLA2G4B
hsa03320__28	0.0212460712593812	DOWN	-2.30425958204685	0.0410291550836354	PPAR signaling pathway: ACSL1
hsa04020__64	0.0213986443805112	DOWN	-2.30155266917513	0.0411967754005949	Calcium signaling pathway: C01330*
hsa04020__12	0.0213986443805112	DOWN	-2.30155266917513	0.0411967754005949	Calcium signaling pathway: C01330
hsa05014__33 34	0.0213986443805112	DOWN	-2.30155266917513	0.0411967754005949	Amyotrophic lateral sclerosis (ALS): NEFH PRPH
hsa04340__52	0.0215521707331698	DOWN	-2.29884575630342	0.0414498759545815	Hedgehog signaling pathway: BCL2*
hsa04630__27	0.0217066551408953	UP	2.2961388434317	0.0417042996009635	Jak-STAT signaling pathway: PIM1
hsa04930__13	0.0220970894501044	UP	2.28937156125242	0.0424110634083209	Type II diabetes mellitus: C00162
hsa05215__43	0.0221758436827649	DOWN	-2.28801810481656	0.042432307346796	Prostate cancer: C05981
hsa05200__223	0.0221759051700658	UP	2.28801810481656	0.042432307346796	Pathways in cancer: CCND1****
hsa05221__17	0.0221759051700658	UP	2.28801810481656	0.042432307346796	Acute myeloid leukemia: CCND1
hsa05220__22	0.0222549652671065	DOWN	-2.2866646483807	0.0425402642287824	Chronic myeloid leukemia: CDKN1B
hsa04210__63	0.0226539528789995	UP	2.27989736620142	0.043258920182561	Apoptosis: FAS*
hsa04071__11	0.0231409310946348	DOWN	-2.27177662758628	0.044054518264254	Sphingolipid signaling pathway: PRKCA
hsa04724__67	0.0231409310946348	DOWN	-2.27177662758628	0.044054518264254	Glutamatergic synapse: PLD1
hsa05222__35	0.0231409310946348	UP	2.27177662758628	0.044054518264254	Small cell lung cancer: NOS2
hsa05152__24 25	0.0237205339114429	UP	2.26230243253528	0.0451122299793534	Tuberculosis: ITGB2 ITGAM
hsa05169__83	0.0239727718835844	UP	2.2582420632277	0.0455458426382761	Epstein-Barr virus infection: GSK3B
hsa05164__24	0.0240573649909706	UP	2.25688860679185	0.0456603927454886	Influenza A: IRF7
hsa04340__15	0.0241422168137936	DOWN	-2.25553515035599	0.0457752022130355	Hedgehog signaling pathway: HHIP
hsa05212__19	0.0242273279873857	DOWN	-2.25418169392013	0.0458902714599776	Pancreatic cancer: MAPK8
hsa04530__11 33	0.0243983309331566	DOWN	-2.25147478104842	0.046167637284392	Tight junction: TJP1 CGN
hsa05020__59	0.0248304215997991	DOWN	-2.24470749886913	0.0469379901267833	Prion diseases: CCL5
hsa05169__117	0.0251808507429304	DOWN	-2.2392936731257	0.0475525814532323	Epstein-Barr virus infection: CDKN1A
hsa04012__47	0.0253576650403335	DOWN	-2.23658676025399	0.0478384062357296	ErbB signaling pathway: PRKCA
hsa05152__126	0.0255355527353942	UP	2.23387984738227	0.0481256806317009	Tuberculosis: NOS2
hsa05200__183	0.0256249007329902	DOWN	-2.23252639094642	0.0482456798369626	Pathways in cancer: BMP2
hsa04662__32 51	0.0257145190330974	DOWN	-2.23117293451056	0.0483659472104005	B cell receptor signaling pathway: BLNK GRB2
hsa04922__50	0.0258044082887928	DOWN	-2.2298194780747	0.0484864831746416	Glucagon signaling pathway: PCK1
hsa05200__224	0.0258945691541335	UP	2.22846602163885	0.0485587778848472	Pathways in cancer: MYC***
hsa05221__12	0.0258945691541335	UP	2.22846602163885	0.0485587778848472	Acute myeloid leukemia: MYC
hsa04014__103	0.0263494705860656	DOWN	-2.22169873945956	0.0493625675286314	Ras signaling pathway: KSR2
hsa04350__11	0.0266257128339667	DOWN	-2.21763837015199	0.0498303928436488	TGF-beta signaling pathway: SMAD4*
hsa04620__76	0.0267183477801274	UP	2.21628491371613	0.0499540054516014	Toll-like receptor signaling pathway: CCL3L3
hsa04115__3	0.0270916762575237	DOWN	-2.2108710879727	0.0505513998886664	p53 signaling pathway: GADD45G
hsa04662__10	0.0270916762575237	UP	2.2108710879727	0.0505513998886664	B cell receptor signaling pathway: GSK3B
hsa04662__27	0.0271857088813335	DOWN	-2.20951763153685	0.0506765347103429	B cell receptor signaling pathway: NFATC1
hsa04152__38	0.0273746194116755	DOWN	-2.20681071866513	0.0509276335391468	AMPK signaling pathway: PFKL
hsa04973__5	0.0273746194116755	DOWN	-2.20681071866513	0.0509276335391468	Carbohydrate digestion and absorption: SLC2A5
hsa04550__47	0.0279481616011748	UP	2.19868998004999	0.0519432202261202	Signaling pathways regulating pluripotency of stem cells: CTNNB1*
hsa04530__20 31	0.0280447522528319	DOWN	-2.19733652361413	0.0520712346670663	Tight junction: ACTB MLLT4
hsa05100__33	0.0281416305038185	UP	2.19598306717827	0.0521995298288993	Bacterial invasion of epithelial cells: DNM1
hsa04152__58	0.0282387970324697	UP	2.19462961074242	0.0523281061380775	AMPK signaling pathway: SCD
hsa04520__7 68	0.0283362525180811	UP	2.19327615430656	0.0524569640211571	Adherens junction: CDH1 CTNNB1
hsa04390__77	0.0287289776496192	DOWN	-2.18786232856313	0.0531316427201127	Hippo signaling pathway: CCND1
hsa04064__116	0.0295285055594618	DOWN	-2.17703467707627	0.0545030078057256	NF-kappa B signaling pathway: GADD45B
hsa04919__45	0.0295285055594618	DOWN	-2.17703467707627	0.0545030078057256	Thyroid hormone signaling pathway: SLC9A1
hsa04114__56	0.0297313524819409	DOWN	-2.17432776420456	0.0548235636050707	Oocyte meiosis: REC8
hsa04670__54	0.0300378690623691	UP	2.17026739489699	0.0553344666354818	Leukocyte transendothelial migration: RAC1*
hsa05168__92 93	0.0301406430226327	UP	2.16891393846113	0.0554694106165787	Herpes simplex infection: IRF9 STAT1
hsa05215__14	0.030659057477733	UP	2.16214665628184	0.0563682671239338	Prostate cancer: CCND1
hsa05150__35	0.0308685075237476	UP	2.15943974341013	0.0566425966091183	Staphylococcus aureus infection: FCAR
hsa04910__46	0.0308685571728244	DOWN	-2.15943974341013	0.0566425966091183	Insulin signaling pathway: FBP1
hsa05200__211	0.0310792846800225	DOWN	-2.15673283053842	0.0569736350378169	Pathways in cancer: CXCL8
hsa04072__36	0.0312912456420268	UP	2.1540259176667	0.0572504874015271	Phospholipase D signaling pathway: MTOR
hsa04152__68	0.0312912456420268	DOWN	-2.1540259176667	0.0572504874015271	AMPK signaling pathway: PPARGC1A**
hsa04530__7 52	0.0313976904360001	DOWN	-2.15267246123084	0.0573335863257961	Tight junction: PARD6A MPP5
hsa05211__41	0.0313976904360001	UP	2.15267246123084	0.0573335863257961	Renal cell carcinoma: PDGFB*
hsa04064__3	0.0316115121928583	DOWN	-2.14996554835913	0.0576679916605638	NF-kappa B signaling pathway: BCL2
hsa04360__19	0.0318265815763755	DOWN	-2.14725863548742	0.0580040220970025	Axon guidance: CDC42
hsa04211__23	0.0319345859071423	UP	2.14590517905156	0.0581444640693028	Longevity regulating pathway - mammal: SOD2
hsa04071__66	0.0325892318287333	DOWN	-2.13778444043641	0.0592789608966019	Sphingolipid signaling pathway: C01245
hsa04062__60	0.032699449491929	UP	2.13643098400056	0.0593645078215793	Chemokine signaling pathway: GSK3A
hsa04213__52	0.032699449491929	UP	2.13643098400056	0.0593645078215793	Longevity regulating pathway - multiple species: SOD2
hsa05200__186	0.0328099862167276	DOWN	-2.1350775275647	0.0595076873564006	Pathways in cancer: PTCH1*
hsa05142__29	0.0330320197342751	UP	2.13237061469299	0.0598526182070423	Chagas disease (American trypanosomiasis): NOS2
hsa05168__10	0.0333674810161481	DOWN	-2.12831024538541	0.0604022127450312	Herpes simplex infection: FOS
hsa04920__6	0.033479947274123	DOWN	-2.12695678894956	0.0605474696131637	Adipocytokine signaling pathway: PTPN11
hsa04014__41	0.0339330608255789	UP	2.12154296320613	0.0613079050877527	Ras signaling pathway: RAC1*
hsa04064__142	0.0340471549846303	UP	2.12018950677027	0.0614549512162538	NF-kappa B signaling pathway: NFKB2*
hsa04742__67	0.0347386287002823	DOWN	-2.11206876815513	0.0626428822723901	Taste transduction: PRKACA
hsa05200__190	0.0350888399382736	UP	2.10800839884756	0.0632137394477624	Pathways in cancer: MYC*
hsa04068__49	0.0360375037634447	DOWN	-2.0971807473607	0.0648606030378473	FoxO signaling pathway: BCL2L11
hsa04152__60	0.036885438707349	UP	2.0877065523097	0.0662597890354769	AMPK signaling pathway: EEF2
hsa04630__30	0.036885438707349	UP	2.0877065523097	0.0662597890354769	Jak-STAT signaling pathway: CDKN1A
hsa04010__15	0.0370079485292047	UP	2.08635309587384	0.0664163660805881	MAPK signaling pathway: NFKB1
hsa04380__38	0.0372540078804639	UP	2.08364618300213	0.0667941610757554	Osteoclast differentiation: FOS
hsa05166__5	0.0375014585347477	UP	2.08093927013041	0.067173727918771	HTLV-I infection: SLC2A1
hsa04151__26	0.0381262118150305	DOWN	-2.07417198795113	0.0681628468129802	PI3K-Akt signaling pathway: RBL2
hsa04152__49	0.0381262118150305	DOWN	-2.07417198795113	0.0681628468129802	AMPK signaling pathway: GYS1
hsa04115__40	0.0386323662132512	UP	2.0687581622077	0.0690021065729078	p53 signaling pathway: PIDD1
hsa05161__31	0.0387597933482187	DOWN	-2.06740470577184	0.0691639617296324	Hepatitis B: ELK1
hsa04668__153	0.0390157192076619	UP	2.06469779290013	0.0694886600864423	TNF signaling pathway: MAPK14*
hsa05010__49	0.0390157192076619	DOWN	-2.06469779290013	0.0694886600864423	Alzheimer's disease: EIF2AK3
hsa04727__47	0.0394022984596417	UP	2.06063742359256	0.0701107185659724	GABAergic synapse: CACNA1A*
hsa04933__43	0.0395318787365849	UP	2.0592839671567	0.0702747399678742	AGE-RAGE signaling pathway in diabetic complications: CASP3
hsa04660__30	0.0404491071018815	UP	2.0498097721057	0.0718373083595797	T cell receptor signaling pathway: CD40LG
hsa04213__53	0.0405816013421689	UP	2.04845631566984	0.072004559888513	Longevity regulating pathway - multiple species: SOD1
hsa04620__39	0.041654858793834	DOWN	-2.03762866418298	0.0738391317675605	Toll-like receptor signaling pathway: IL6
hsa05205__220	0.0423377731512505	UP	2.0308613820037	0.0749789592377	Proteoglycans in cancer: FAS
hsa04510__23 4 5	0.0424754865352327	UP	2.02950792556784	0.0750107511275397	Focal adhesion: TLN1 ITGB1 ITGA11
hsa05031__101	0.0424754865352327	DOWN	-2.02950792556784	0.0750107511275397	Amphetamine addiction: FOS*
hsa05164__68	0.0424754865352327	UP	2.02950792556784	0.0750107511275397	Influenza A: EIF2S1
hsa04550__53 64	0.0433097465340702	DOWN	-2.0213871869527	0.0763405382153076	Signaling pathways regulating pluripotency of stem cells: SMAD1 SMAD4
hsa04930__10	0.0433097465340702	DOWN	-2.0213871869527	0.0763405382153076	Type II diabetes mellitus: C00031
hsa04151__73	0.0435908920367556	DOWN	-2.01868027408098	0.0767640919747551	PI3K-Akt signaling pathway: MAPK1
hsa04960__13	0.0437320418821401	DOWN	-2.01732681764513	0.0769405493413307	Aldosterone-regulated sodium reabsorption: FXYD4
hsa04310__33	0.0438735775148886	UP	2.01597336120927	0.0770452823836222	Wnt signaling pathway: CCND1
hsa04930__15	0.0438735775148886	DOWN	-2.01597336120927	0.0770452823836222	Type II diabetes mellitus: C00031*
hsa04950__22	0.0443005070855261	UP	2.0119129919017	0.0777223649054188	Maturity onset diabetes of the young: NR5A2
hsa05032__31	0.0444435938196873	DOWN	-2.01055953546584	0.0777555984983169	Morphine addiction: GABRR3
hsa05032__33	0.0444435938196873	DOWN	-2.01055953546584	0.0777555984983169	Morphine addiction: GABRR3*
hsa05032__55	0.0444435938196873	DOWN	-2.01055953546584	0.0777555984983169	Morphine addiction: GABRR3**
hsa04750__44	0.0445870492631761	DOWN	-2.00920607902998	0.0778615850980557	Inflammatory mediator regulation of TRP channels: TRPA1
hsa04750__63	0.0445870492631761	DOWN	-2.00920607902998	0.0778615850980557	Inflammatory mediator regulation of TRP channels: TRPA1*
hsa03320__36	0.0457490098822574	DOWN	-1.99837842754313	0.0797424764088698	PPAR signaling pathway: SLC27A4
hsa05164__41 42	0.0457490098822574	UP	1.99837842754313	0.0797424764088698	Influenza A: STAT1 IRF9
hsa05132__54	0.045896030293637	UP	1.99702497110727	0.0799245977031918	Salmonella infection: IL1B
hsa04022__60	0.0461912652675402	UP	1.99431805823555	0.0803642476275075	cGMP-PKG signaling pathway: TRPC6*
hsa04211__52	0.0463394814417205	DOWN	-1.9929646017997	0.0805475352719637	Longevity regulating pathway - mammal: PPARG
hsa04750__7	0.0466370790917463	UP	1.99025768892798	0.0808013769614054	Inflammatory mediator regulation of TRP channels: TRPV1
hsa04750__58	0.0466370790917463	UP	1.99025768892798	0.0808013769614054	Inflammatory mediator regulation of TRP channels: TRPV1**
hsa04072__57	0.0467865343980889	UP	1.98890423249213	0.0808013769614054	Phospholipase D signaling pathway: C06124
hsa04380__72	0.0467865343980889	DOWN	-1.98890423249213	0.0808013769614054	Osteoclast differentiation: MAPK1
hsa05200__173	0.0467865343980889	DOWN	-1.98890423249213	0.0808013769614054	Pathways in cancer: CCNA1
hsa05221__16	0.0467865343980889	DOWN	-1.98890423249213	0.0808013769614054	Acute myeloid leukemia: CCNA1
hsa05221__6	0.0467865343980889	DOWN	-1.98890423249213	0.0808013769614054	Acute myeloid leukemia: CEBPA
hsa04620__46	0.046936356222544	UP	1.98755077605627	0.0809856871828836	Toll-like receptor signaling pathway: TNF
hsa04310__34	0.0473882455490527	UP	1.9834904067487	0.0816155026458937	Wnt signaling pathway: FOSL1
hsa04931__144	0.0473882455490527	DOWN	-1.9834904067487	0.0816155026458937	Insulin resistance: C00533*
hsa04360__3	0.047539685979348	DOWN	-1.98213695031284	0.0818013461128159	Axon guidance: GNAI1
hsa04064__36	0.0479964506097605	UP	1.97807658100527	0.0824363169065264	NF-kappa B signaling pathway: PLCG1
hsa04921__41	0.0479964506097605	DOWN	-1.97807658100527	0.0824363169065264	Oxytocin signaling pathway: PTGS2
hsa04390__76	0.0483030046202365	DOWN	-1.97536966813355	0.082887073681666	Hippo signaling pathway: MYC
hsa04213__60	0.0484568973482999	DOWN	-1.9740162116977	0.0830752829538827	Longevity regulating pathway - multiple species: CAT
hsa04210__51	0.0486112016468377	DOWN	-1.97266275526184	0.0832638540514202	Apoptosis: LMNA
hsa04213__54	0.0487659183331362	UP	1.97130929882598	0.0834527873843014	Longevity regulating pathway - multiple species: SOD2*
hsa04921__59	0.0495457162329061	DOWN	-1.9645420166467	0.0847101008204099	Oxytocin signaling pathway: CCND1
hsa05205__145	0.0497029244461888	UP	1.96318856021084	0.0849016318494444	Proteoglycans in cancer: PXN
hsa04071__69	0.0498605507868826	UP	1.96183510377498	0.0850935285454609	Sphingolipid signaling pathway: RAC1
hsa03320__46	0.0500185960775682	UP	1.96048164733912	0.0851312880704264	PPAR signaling pathway: APOA2
hsa04024__59	0.0500185960775682	DOWN	-1.96048164733912	0.0851312880704264	cAMP signaling pathway: MLLT4
hsa04623__9	0.0500185960775682	UP	1.96048164733912	0.0851312880704264	Cytosolic DNA-sensing pathway: IKBKE
hsa04670__73	0.0501770611414759	UP	1.95912819090327	0.0853237084930618	Leukocyte transendothelial migration: MYL12B*
hsa04151__110	0.0506549832145148	DOWN	-1.9550678215957	0.086058511265889	PI3K-Akt signaling pathway: BCL2**
hsa04210__62	0.0508151356165015	UP	1.95371436515984	0.0862526104999153	Apoptosis: TP53AIP1
hsa04151__51	0.052604971637394	UP	1.93882634436541	0.0891296138022213	PI3K-Akt signaling pathway: NOS3
hsa04810__48	0.052604971637394	DOWN	-1.93882634436541	0.0891296138022213	Regulation of actin cytoskeleton: IQGAP2
hsa04068__96	0.0529359933293964	DOWN	-1.9361194314937	0.0896096679873296	FoxO signaling pathway: CCNG2
hsa04630__7	0.0536032597875267	UP	1.93070560575027	0.0906575383805245	Jak-STAT signaling pathway: BCL2
hsa03320__37	0.0537711694177542	DOWN	-1.92935214931441	0.0907781018292544	PPAR signaling pathway: HMGCS2
hsa04612__18	0.0537711694177542	UP	1.92935214931441	0.0907781018292544	Antigen processing and presentation: KIR2DS2
hsa05145__33	0.0549588724382538	UP	1.91987795426341	0.0926167904138824	Toxoplasmosis: STAT3
hsa05169__125	0.0549588724382538	UP	1.91987795426341	0.0926167904138824	Epstein-Barr virus infection: STAT3
hsa03320__39	0.0551303166040678	UP	1.91852449782755	0.0928224595869565	PPAR signaling pathway: MMP1
hsa04360__51	0.0553022063695245	DOWN	-1.91717104139169	0.0929453003294603	Axon guidance: FYN
hsa04650__39	0.0553022063695245	UP	1.91717104139169	0.0929453003294603	Natural killer cell mediated cytotoxicity: FAS
hsa04010__107	0.0565179823534932	UP	1.90769684634069	0.0947344235880586	MAPK signaling pathway: MAP3K2
hsa04066__63	0.0565179823534932	UP	1.90769684634069	0.0947344235880586	HIF-1 signaling pathway: TIMP1*
hsa04066__57	0.0565179823534932	UP	1.90769684634069	0.0947344235880586	HIF-1 signaling pathway: TIMP1
hsa05166__34 35 36	0.0566934591456093	DOWN	-1.90634338990484	0.0949438589434937	HTLV-I infection: MYC TRRAP KAT5
hsa05212__31	0.0570457976160272	UP	1.90363647703312	0.0954488456994792	Pancreatic cancer: RAC1*
hsa04670__55	0.0577559238148357	UP	1.89822265128969	0.0964652274205123	Leukocyte transendothelial migration: RAC2
hsa04740__10	0.0577559238148357	UP	1.89822265128969	0.0964652274205123	Olfactory transduction: ANO2
hsa05205__129	0.0579345989727147	UP	1.89686919485384	0.096591935643062	Proteoglycans in cancer: AKT3*
hsa05211__46	0.0579345989727147	UP	1.89686919485384	0.096591935643062	Renal cell carcinoma: AKT3
hsa04350__32	0.0584733827099245	DOWN	-1.89280882554627	0.0974037997446348	TGF-beta signaling pathway: RPS6KB1
hsa04064__51	0.0588348789359981	UP	1.89010191267455	0.097746010186331	NF-kappa B signaling pathway: TNFAIP3
hsa04913__36	0.0588348789359981	UP	1.89010191267455	0.097746010186331	Ovarian steroidogenesis: CYP19A1
hsa04913__37	0.0588348789359981	UP	1.89010191267455	0.097746010186331	Ovarian steroidogenesis: CYP19A1*
hsa04064__115	0.0601147577434866	UP	1.88062771762355	0.0997841252650276	NF-kappa B signaling pathway: XIAP
hsa05162__78	0.060670300913261	UP	1.87656734831598	0.100617383421022	Measles: FAS
hsa05140__26	0.0610430213833309	UP	1.87386043544426	0.101057125268087	Leishmaniasis: C00533
hsa05142__21	0.0610430213833309	DOWN	-1.87386043544426	0.101057125268087	Chagas disease (American trypanosomiasis): TICAM1
hsa04920__31	0.061605656787672	UP	1.86980006613669	0.101809172474965	Adipocytokine signaling pathway: AGRP
hsa05161__66 67	0.061605656787672	DOWN	-1.86980006613669	0.101809172474965	Hepatitis B: NFKB1 NFKBIA
hsa05014__49	0.0617941532790034	DOWN	-1.86844660970084	0.102030943770868	Amyotrophic lateral sclerosis (ALS): C00001
hsa04730__7	0.0623625088649252	DOWN	-1.86438624039326	0.102878976433007	Long-term depression: GNA13
hsa05014__54	0.0625529189675868	UP	1.86303278395741	0.103102574333417	Amyotrophic lateral sclerosis (ALS): PPP3CA
hsa05213__29	0.0638992935809059	UP	1.85355858890641	0.1052294238725	Endometrial cancer: CCND1
hsa05014__2	0.0642883384865458	DOWN	-1.85085167603469	0.105777397562364	Amyotrophic lateral sclerosis (ALS): SLC1A2
hsa04151__28	0.0650722952009749	UP	1.84543785029126	0.106973615645347	PI3K-Akt signaling pathway: BCL2L11
hsa04723__9	0.0656654235703609	DOWN	-1.84137748098369	0.10766608279992	Retrograde endocannabinoid signaling: PRKCA
hsa04725__20	0.0656654235703609	DOWN	-1.84137748098369	0.10766608279992	Cholinergic synapse: PRKCA
hsa04726__18	0.0656654235703609	DOWN	-1.84137748098369	0.10766608279992	Serotonergic synapse: PRKCA
hsa05145__29	0.0662629747411475	UP	1.83731711167612	0.108551115552412	Toxoplasmosis: C06314
hsa04152__78	0.0672689165288228	UP	1.83054982949684	0.11010304369134	AMPK signaling pathway: CCNA2
hsa04115__31	0.0678784748324534	DOWN	-1.82648946018926	0.110907525400156	p53 signaling pathway: ADGRB1
hsa05321__94	0.0678784748324534	UP	1.82648946018926	0.110907525400156	Inflammatory bowel disease (IBD): IL22
hsa05161__10	0.0680826677112455	UP	1.82513600375341	0.111144511406977	Hepatitis B: CASP3
hsa04015__11	0.0689044963684004	UP	1.81972217800998	0.112388497114778	Rap1 signaling pathway: RAC1
hsa05205__120	0.0695262023001596	UP	1.81566180870241	0.113304192647008	Proteoglycans in cancer: PLAU
hsa05120__50	0.0701525068173524	DOWN	-1.81160143939483	0.114225788829987	Epithelial cell signaling in Helicobacter pylori infection: EGFR
hsa04621__29	0.070362300978182	UP	1.81024798295898	0.114468193539397	NOD-like receptor signaling pathway: CASP5
hsa04650__36	0.0709947736769579	UP	1.80618761365141	0.115397214307097	Natural killer cell mediated cytotoxicity: CASP3
hsa05161__214	0.0731367591090898	UP	1.79265304929283	0.118776119590302	Hepatitis B: CDKN1B
hsa04015__82	0.0735714383153178	UP	1.78994613642112	0.119275869365386	Rap1 signaling pathway: ITGA2B
hsa04350__21	0.0735714383153178	DOWN	-1.78994613642112	0.119275869365386	TGF-beta signaling pathway: CDKN2B
hsa04210__107	0.0748881570561807	DOWN	-1.78182539780598	0.121305902679796	Apoptosis: MCL1
hsa04510__20 69	0.0755537128311936	DOWN	-1.77776502849841	0.122068294419443	Focal adhesion: VASP ACTB
hsa04950__8	0.0755537128311936	DOWN	-1.77776502849841	0.122068294419443	Maturity onset diabetes of the young: NEUROD1
hsa05161__130	0.0755537128311936	UP	1.77776502849841	0.122068294419443	Hepatitis B: FASLG*
hsa04621__42	0.0757766314345496	UP	1.77641157206255	0.122323273595806	NOD-like receptor signaling pathway: MAPK8
hsa04360__125	0.0760000864402125	DOWN	-1.77505811562669	0.122578680189836	Axon guidance: ENAH*
hsa05200__76	0.0764486091802427	UP	1.77235120275498	0.123196343610357	Pathways in cancer: RAC1
hsa04115__22	0.0771254383224778	UP	1.7682908334474	0.124074228260219	p53 signaling pathway: STEAP3
hsa04152__82	0.0771254383224778	DOWN	-1.7682908334474	0.124074228260219	AMPK signaling pathway: HMGCR
hsa04380__51	0.0778071426472333	UP	1.76423046413983	0.12495694105483	Osteoclast differentiation: FOS*
hsa04670__76	0.0778071426472333	UP	1.76423046413983	0.12495694105483	Leukocyte transendothelial migration: CDC42
hsa04068__57	0.0791852720371202	DOWN	-1.75610972552469	0.126953179315485	FoxO signaling pathway: IL7R
hsa04917__47	0.0791852720371202	DOWN	-1.75610972552469	0.126953179315485	Prolactin signaling pathway: INS
hsa04976__36	0.0796490360669061	UP	1.75340281265298	0.12758784208842	Bile secretion: SLC10A1
hsa04912__19	0.0815262182182123	DOWN	-1.74257516116612	0.130483615018757	GnRH signaling pathway: MAPK7
hsa04915__30	0.0820010805632676	UP	1.7398682482944	0.131131940747557	Estrogen signaling pathway: CREB3*
hsa04010__79	0.0824781837534867	UP	1.73716133542269	0.131782744279593	MAPK signaling pathway: HSPB1
hsa04064__4	0.0836807917716426	UP	1.7303940532434	0.133590660780728	NF-kappa B signaling pathway: BIRC2
hsa05160__77	0.0839230090163243	UP	1.72904059680755	0.13386361115592	Hepatitis C: NFKB1*
hsa03320__44	0.0841657935345339	DOWN	-1.72768714037169	0.134137002588116	PPAR signaling pathway: FABP1
hsa04066__64	0.0844091462090434	DOWN	-1.72633368393583	0.134410835361689	HIF-1 signaling pathway: LTBR
hsa03320__7	0.0846530679226062	DOWN	-1.72498022749998	0.134685109760014	PPAR signaling pathway: AQP7
hsa04520__1 13	0.0848975595579531	DOWN	-1.72362677106412	0.134959826065477	Adherens junction: SMAD4 SMAD2
hsa05134__70	0.0853882561247765	DOWN	-1.7209198581924	0.135625133777223	Legionellosis: IL6
hsa04722__34	0.0858812429707104	UP	1.71821294532069	0.136292952315849	Neurotrophin signaling pathway: GSK3B
hsa04014__58 59	0.0876248348075881	UP	1.70873875026969	0.138942670551441	Ras signaling pathway: STK4 STK4
hsa04210__4	0.0881282152697526	DOWN	-1.70603183739797	0.139623032455198	Apoptosis: DFFA
hsa04210__24	0.0883807784721241	UP	1.70467838096212	0.13990520871872	Apoptosis: CASP10
hsa05142__84	0.0891419705455436	UP	1.70061801165455	0.140991382706293	Chagas disease (American trypanosomiasis): NFKB1*
hsa05169__79	0.0904223517764992	DOWN	-1.69385072947526	0.142896214455881	Epstein-Barr virus infection: ATF2
hsa04728__36	0.0919782957539542	DOWN	-1.68572999086012	0.145232956068639	Dopaminergic synapse: TH
hsa04064__95	0.0930274897710493	UP	1.68031616511669	0.146766291586735	NF-kappa B signaling pathway: BCL2L1**
hsa04933__35	0.0948866748613941	UP	1.67084197006569	0.149573877570939	AGE-RAGE signaling pathway in diabetic complications: CCND1
hsa04950__11	0.0954233038222407	UP	1.66813505719397	0.150293703170151	Maturity onset diabetes of the young: HNF4G
hsa04151__27	0.095962360419295	UP	1.66542814432226	0.151016143406914	PI3K-Akt signaling pathway: FASLG
hsa04933__22	0.0965038516671291	UP	1.66272123145054	0.151741202746892	AGE-RAGE signaling pathway in diabetic complications: EDN1
hsa05161__78	0.0967755124760321	UP	1.66136777501469	0.152041127042194	Hepatitis B: TNF
hsa04210__31 32 33	0.097047784576237	UP	1.66001431857883	0.15221434659328	Apoptosis: TRAF2 RIPK1 TRADD
hsa04921__55	0.097047784576237	UP	1.66001431857883	0.15221434659328	Oxytocin signaling pathway: PTGS2*
hsa04973__36	0.0981430033988207	DOWN	-1.6546004928354	0.153803755951947	Carbohydrate digestion and absorption: SLC2A2
hsa04014__69	0.0989708789528787	DOWN	-1.65054012352783	0.154971901293716	Ras signaling pathway: PLCE1*
hsa04115__56	0.0992480728828465	UP	1.64918666709197	0.155276543669333	p53 signaling pathway: SESN3
hsa04933__12	0.0998043191008555	DOWN	-1.64647975422026	0.156016901489607	AGE-RAGE signaling pathway in diabetic complications: EGR1
hsa04917__56	0.100363048947732	DOWN	-1.64377284134854	0.156759907708054	Prolactin signaling pathway: LHCGR
hsa04932__58	0.100643347412542	UP	1.64241938491269	0.157067150986849	Non-alcoholic fatty liver disease (NAFLD): BAX
hsa04750__39	0.10120581578302	DOWN	-1.63971247204097	0.157813882038418	Inflammatory mediator regulation of TRP channels: C01245*
hsa05168__27	0.101770785214709	DOWN	-1.63700555916926	0.158563271491243	Herpes simplex infection: IRF3
hsa04933__26	0.102054210004687	DOWN	-1.6356521027334	0.158873123942674	AGE-RAGE signaling pathway in diabetic complications: IL6
hsa04390__74	0.102908255107949	DOWN	-1.63159173342583	0.160070042506487	Hippo signaling pathway: AXIN1
hsa04919__88	0.103194196617043	DOWN	-1.63023827698997	0.160382047513171	Thyroid hormone signaling pathway: FOXO1
hsa04064__132	0.103767974557566	UP	1.62753136411826	0.161140515862534	NF-kappa B signaling pathway: VCAM1
hsa04724__33 70 69	0.104344284845126	UP	1.62482445124654	0.16190166079603	Glutamatergic synapse: ITPR1 HOMER3 HOMER3
hsa04933__62	0.105213513595538	UP	1.62076408193897	0.163115670004964	AGE-RAGE signaling pathway in diabetic complications: AGER**
hsa04950__20	0.107264063972237	UP	1.61128988688797	0.166157606103737	Maturity onset diabetes of the young: NKX6-1
hsa04340__31	0.107559566690616	DOWN	-1.60993643045211	0.166478110223779	Hedgehog signaling pathway: GLI1***
hsa04950__1	0.107855713733841	UP	1.60858297401626	0.166799083214722	Maturity onset diabetes of the young: HNF1B
hsa04012__65	0.108152505963142	DOWN	-1.6072295175804	0.167120525250612	ErbB signaling pathway: MYC
hsa04370__25	0.109046762372437	UP	1.60316914827283	0.168363900162538	VEGF signaling pathway: PXN
hsa04360__4	0.109346143948474	DOWN	-1.60181569183697	0.168687524202941	Axon guidance: GNAI1*
hsa05169__30	0.109646175009278	UP	1.60046223540111	0.169011618410528	Epstein-Barr virus infection: FGR
hsa04710__23	0.110248189017484	UP	1.5977553225294	0.169661217988413	Circadian rhythm: BHLHE41
hsa05205__256	0.110248189017484	DOWN	-1.5977553225294	0.169661217988413	Proteoglycans in cancer: ACTB
hsa05160__22 23	0.110852811256351	UP	1.59504840965769	0.170452072300068	Hepatitis C: STAT1 IRF9
hsa04310__36	0.111460048576591	UP	1.59234149678597	0.17124565108374	Wnt signaling pathway: MYC
hsa05161__57	0.111764650030678	UP	1.59098804035011	0.171573347555264	Hepatitis B: STAT3*
hsa05205__17	0.112375822798809	DOWN	-1.5882811274784	0.17237075186854	Proteoglycans in cancer: AKT3
hsa04921__54	0.113297519399878	UP	1.58422075817083	0.17364277239182	Oxytocin signaling pathway: RCAN1
hsa04724__13	0.114225066041264	UP	1.58016038886326	0.17492167815121	Glutamatergic synapse: GRM5
hsa04360__145	0.114846903709054	DOWN	-1.57745347599154	0.175730726440809	Axon guidance: ABLIM3
hsa04976__95 96	0.115158735825369	UP	1.57610001955569	0.176064495212261	Bile secretion: SLC51A SLC51B
hsa04912__17	0.115471305420243	DOWN	-1.57474656311983	0.176398847873688	GnRH signaling pathway: MAPK14
hsa04620__29	0.116098373300324	UP	1.57203965024811	0.177212707905206	Toll-like receptor signaling pathway: CXCL8
hsa05010__50	0.116412909169748	DOWN	-1.57068619381226	0.177548584683407	Alzheimer's disease: ERN1
hsa04062__43	0.116728114119363	UP	1.5693327373764	0.177884936277602	Chemokine signaling pathway: STAT1
hsa05217__22	0.1170439889938	DOWN	-1.56797928094054	0.178221762819571	Basal cell carcinoma: LEF1
hsa04152__35	0.11736053463703	UP	1.56662582450469	0.178559064439659	AMPK signaling pathway: PFKFB1
hsa04917__46	0.117677751892355	DOWN	-1.56527236806883	0.178896841266776	Prolactin signaling pathway: GCK
hsa04933__28	0.118953353876942	UP	1.5598585423254	0.18054390301678	AGE-RAGE signaling pathway in diabetic complications: VCAM1
hsa05217__10	0.118953353876942	DOWN	-1.5598585423254	0.18054390301678	Basal cell carcinoma: PTCH1*
hsa04066__55	0.119595206417562	UP	1.55715162945368	0.181225316821451	HIF-1 signaling pathway: ANGPT1
hsa04360__20	0.119595206417562	DOWN	-1.55715162945368	0.181225316821451	Axon guidance: ROCK1
hsa04726__45	0.120239683498887	DOWN	-1.55444471658197	0.18205508887543	Serotonergic synapse: TRPC1
hsa04024__77	0.120887048147696	UP	1.55173780371026	0.182593861309904	cAMP signaling pathway: RHOA*
hsa04921__33	0.120887048147696	UP	1.55173780371026	0.182593861309904	Oxytocin signaling pathway: C00942
hsa05166__62 63	0.120887048147696	DOWN	-1.55173780371026	0.182593861309904	HTLV-I infection: ANAPC10 CDC20
hsa05213__27	0.121863075361729	DOWN	-1.54767743440268	0.183920255907381	Endometrial cancer: ELK1
hsa04210__3	0.122189783344662	UP	1.54632397796683	0.184265331384125	Apoptosis: BCL2L1
hsa05164__70	0.124828147364699	UP	1.53549632647997	0.187942378924895	Influenza A: RNASEL
hsa05168__83	0.124828147364699	UP	1.53549632647997	0.187942378924895	Herpes simplex infection: RNASEL
hsa04062__38	0.12516104282247	DOWN	-1.53414287004411	0.188292713741731	Chemokine signaling pathway: NCF1
hsa04015__14	0.126499549246788	DOWN	-1.52872904430068	0.190154122427771	Rap1 signaling pathway: MAPK14
hsa05210__22	0.127172968739116	UP	1.52602213142897	0.191013595732053	Colorectal cancer: MYC
hsa05140__43	0.128868721776844	UP	1.51925484924968	0.193406012954225	Leishmaniasis: MAPK14
hsa04064__135	0.129551921888724	DOWN	-1.51654793637797	0.194276186136403	NF-kappa B signaling pathway: CCL19
hsa04330__11	0.130581991253477	UP	1.5124875670704	0.195664722141375	Notch signaling pathway: PTCRA
hsa04912__33	0.130926756078299	DOWN	-1.51113411063454	0.196024999737948	GnRH signaling pathway: ELK1
hsa04724__36	0.13127222643987	UP	1.50978065419868	0.196385759140538	Glutamatergic synapse: TRPC1
hsa05161__68	0.131965287011075	UP	1.50707374132697	0.197265532453309	Hepatitis B: JUN
hsa04666__49	0.133359910157762	UP	1.50165991558354	0.199191789496371	Fc gamma R-mediated phagocytosis: ARF6*
hsa04931__135	0.133710341895046	DOWN	-1.50030645914768	0.199398200333961	Insulin resistance: SREBF1**
hsa05134__59	0.133710341895046	UP	1.50030645914768	0.199398200333961	Legionellosis: HSPA1A
hsa04064__113	0.136183344556518	UP	1.49083226409668	0.202925062983107	NF-kappa B signaling pathway: CFLAR
hsa04919__44	0.137253950599144	UP	1.48677189478911	0.204358298871467	Thyroid hormone signaling pathway: PFKFB2
hsa04919__100	0.138691508486212	DOWN	-1.48135806904568	0.206171949719615	Thyroid hormone signaling pathway: CTNNB1*
hsa05142__18	0.138691508486212	DOWN	-1.48135806904568	0.206171949719615	Chagas disease (American trypanosomiasis): FOS
hsa04670__2	0.139414623015637	UP	1.47865115617397	0.207083064542594	Leukocyte transendothelial migration: MMP2
hsa05222__36	0.140140636337103	UP	1.47594424330225	0.207832877409168	Small cell lung cancer: PTGS2
hsa05321__122	0.140140636337103	DOWN	-1.47594424330225	0.207832877409168	Inflammatory bowel disease (IBD): IL4**
hsa05200__66	0.141601384456559	UP	1.47053041755883	0.209833597313781	Pathways in cancer: CCND1
hsa04932__7	0.14196839302186	DOWN	-1.46917696112297	0.210211670991391	Non-alcoholic fatty liver disease (NAFLD): SREBF1
hsa04064__131	0.142336131760713	UP	1.46782350468711	0.210590229589275	NF-kappa B signaling pathway: CCL4L1
hsa04014__97	0.143443736790104	UP	1.46376313537954	0.212061983814795	Ras signaling pathway: PAK4
hsa05150__66	0.143814403988987	UP	1.46240967894368	0.212442818471153	Staphylococcus aureus infection: IL10
hsa05032__38	0.144557941310958	DOWN	-1.45970276607197	0.213373426334084	Morphine addiction: CACNA1A
hsa04728__60	0.144930812976841	DOWN	-1.45834930963611	0.213755885073379	Dopaminergic synapse: CACNA1A
hsa05210__40	0.145678766166597	DOWN	-1.4556423967644	0.214690511080028	Colorectal cancer: CASP9
hsa05168__91 92	0.147183533453242	UP	1.45022857102097	0.216738134293606	Herpes simplex infection: STAT1 IRF9
hsa04720__32	0.147561575757231	DOWN	-1.44887511458511	0.217124667852652	Long-term potentiation: ITPR1
hsa04620__23	0.148700156011412	DOWN	-1.44481474527754	0.21845785234202	Toll-like receptor signaling pathway: CD40
hsa05010__12	0.148700156011412	UP	1.44481474527754	0.21845785234202	Alzheimer's disease: CASP3
hsa04950__21	0.149462928217376	UP	1.44210783240582	0.219406907906601	Maturity onset diabetes of the young: PKLR
hsa04340__32	0.149845432200181	DOWN	-1.44075437596997	0.219796695631647	Hedgehog signaling pathway: PTCH1***
hsa05166__32	0.150228682441661	UP	1.43940091953411	0.220186969038909	HTLV-I infection: STAT5A
hsa04912__15	0.153321639718567	DOWN	-1.42857326804725	0.224545098231635	GnRH signaling pathway: CAMK2A
hsa04151__5	0.153711639997144	DOWN	-1.4272198116114	0.224940943578374	PI3K-Akt signaling pathway: EIF4B
hsa05132__6	0.15410239400147	DOWN	-1.42586635517554	0.225162051577575	Salmonella infection: NFKB1
hsa05160__54	0.15410239400147	UP	1.42586635517554	0.225162051577575	Hepatitis C: IRF1
hsa04115__24	0.155279185757133	UP	1.42180598586797	0.226705198164454	p53 signaling pathway: SERPINB5
hsa05231__60	0.155672962045924	UP	1.42045252943211	0.227103645717617	Choline metabolism in cancer: PRKCA
hsa05211__43	0.156462787585446	UP	1.4177456165604	0.228078803625332	Renal cell carcinoma: RAP1A
hsa04621__44	0.158051550980459	UP	1.41233179081697	0.230037849955292	NOD-like receptor signaling pathway: MAPK14
hsa04742__31	0.158051550980459	DOWN	-1.41233179081697	0.230037849955292	Taste transduction: C00076*
hsa05142__36	0.159251119720698	UP	1.4082714215094	0.23160437612631	Chagas disease (American trypanosomiasis): SMAD2
hsa04924__58	0.162076885338465	DOWN	-1.39879722645839	0.235349665804464	Renin secretion: PPP3CA
hsa05031__59	0.162076885338465	DOWN	-1.39879722645839	0.235349665804464	Amphetamine addiction: PPP3CA
hsa04971__37	0.162483636294753	DOWN	-1.39744377002254	0.235758110114163	Gastric acid secretion: KCNQ1
hsa04310__35	0.162891156925988	DOWN	-1.39609031358668	0.236167040018466	Wnt signaling pathway: JUN
hsa04670__15	0.16452890865983	DOWN	-1.39067648784325	0.238357609384596	Leukocyte transendothelial migration: PECAM1
hsa04340__20 22	0.164940329951443	DOWN	-1.38932303140739	0.238769553142344	Hedgehog signaling pathway: GLI1 SUFU*
hsa04024__43	0.165352483458456	DOWN	-1.38796957497154	0.239181921800184	cAMP signaling pathway: MAPK8
hsa04660__14	0.167424883973853	DOWN	-1.38120229279225	0.241993351528361	T cell receptor signaling pathway: NFKB1
hsa03320__9	0.167841695537114	DOWN	-1.37984883635639	0.242409335829544	PPAR signaling pathway: PCK1
hsa04062__22 41	0.168259285867913	UP	1.37849537992054	0.242639446005993	Chemokine signaling pathway: CRK PTK2B
hsa05133__24	0.168259285867913	DOWN	-1.37849537992054	0.242639446005993	Pertussis: NFKB1
hsa04923__31	0.168677655654905	DOWN	-1.37714192348468	0.243056223140772	Regulation of lipolysis in adipocytes: PRKACA*
hsa04152__81	0.170781220425177	DOWN	-1.37037464130539	0.245522504344995	AMPK signaling pathway: LIPE
hsa04727__13	0.170781220425177	DOWN	-1.37037464130539	0.245522504344995	GABAergic synapse: CACNA1A
hsa05134__7	0.170781220425177	UP	1.37037464130539	0.245522504344995	Legionellosis: IL18
hsa04210__84	0.171204281322513	DOWN	-1.36902118486954	0.245942541746944	Apoptosis: FAS**
hsa04066__62	0.171628126452205	UP	1.36766772843368	0.246363063104425	HIF-1 signaling pathway: NPPA
hsa05321__75	0.1729043739861	UP	1.36360735912611	0.24800558680907	Inflammatory bowel disease (IBD): IL10
hsa04912__43	0.173759139184818	DOWN	-1.36090044625439	0.24904151222599	GnRH signaling pathway: PTK2B
hsa04151__37	0.174617057434349	DOWN	-1.35819353338268	0.249699734337247	PI3K-Akt signaling pathway: G6PC
hsa04360__89	0.174617057434349	DOWN	-1.35819353338268	0.249699734337247	Axon guidance: CAMK2A
hsa04728__71 72	0.174617057434349	DOWN	-1.35819353338268	0.249699734337247	Dopaminergic synapse: CLOCK ARNTL
hsa04520__64	0.175047200617181	UP	1.35684007694682	0.250124479056793	Adherens junction: CTNND1**
hsa04010__119	0.176342374345052	UP	1.35277970763925	0.251783678871089	MAPK signaling pathway: NFATC3
hsa04932__96	0.182925545606726	DOWN	-1.33247786110139	0.260984890049384	Non-alcoholic fatty liver disease (NAFLD): IL6*
hsa05162__44	0.183370815027174	UP	1.33112440466554	0.261421670285326	Measles: PRKCQ
hsa04917__34	0.185159924179632	UP	1.32571057892211	0.26377217402087	Prolactin signaling pathway: ELF5
hsa04970__39	0.185609169023714	UP	1.32435712248625	0.264011892667488	Salivary secretion: KCNN4
hsa05161__125	0.185609212460751	DOWN	-1.32435712248625	0.264011892667488	Hepatitis B: CDKN1A
hsa04066__11	0.186961913622541	UP	1.32029675317868	0.265734822766078	HIF-1 signaling pathway: SLC2A1
hsa05205__109	0.187867750825833	UP	1.31758984030696	0.26682048662263	Proteoglycans in cancer: SMAD2
hsa04920__1	0.189232573516947	DOWN	-1.31352947099939	0.268555895497239	Adipocytokine signaling pathway: C00195
hsa04810__31	0.190146506988848	UP	1.31082255812768	0.269649272929846	Regulation of actin cytoskeleton: MSN
hsa05160__55	0.19060469103918	DOWN	-1.30946910169182	0.270095184360949	Hepatitis C: MAPK14
hsa04666__40	0.192445556644282	UP	1.30405527594839	0.272498267471444	Fc gamma R-mediated phagocytosis: PLA2G6
hsa04922__24	0.196634633201587	DOWN	-1.29187416802568	0.277802694269066	Glucagon signaling pathway: PFKL
hsa04014__64	0.19663522265985	UP	1.29187416802568	0.277802694269066	Ras signaling pathway: PIK3R5*
hsa04933__78	0.19663522265985	DOWN	-1.29187416802568	0.277802694269066	AGE-RAGE signaling pathway in diabetic complications: TGFB1
hsa04210__73	0.198991486555199	UP	1.28510688584639	0.280709461889804	Apoptosis: TRAF1
hsa04390__95	0.198991486555199	DOWN	-1.28510688584639	0.280709461889804	Hippo signaling pathway: AFP
hsa04151__102	0.199939747798037	DOWN	-1.28239997297468	0.281835548471502	PI3K-Akt signaling pathway: C8orf44-SGK3
hsa04530__22 33	0.200891304757674	DOWN	-1.27969306010296	0.282964588935285	Tight junction: MYL12B CGN
hsa04064__133	0.201846161891875	UP	1.27698614723125	0.283883935774576	NF-kappa B signaling pathway: CXCL2
hsa05152__120	0.201846161891875	DOWN	-1.27698614723125	0.283883935774576	Tuberculosis: TGFB1
hsa04360__35	0.202324829408475	UP	1.27563269079539	0.284344318966735	Axon guidance: ROCK1*
hsa04010__14	0.203765794349885	DOWN	-1.27157232148782	0.28615540178134	MAPK signaling pathway: MAPT
hsa04730__20	0.205214214318874	DOWN	-1.26751195218025	0.287974241004603	Long-term depression: C00025
hsa04064__54	0.205698680170645	DOWN	-1.26615849574439	0.288438671672121	NF-kappa B signaling pathway: CCL13
hsa05133__60	0.206670103882206	DOWN	-1.26345158287268	0.289584731688788	Pertussis: C5
hsa04919__43	0.210096308488099	UP	1.25397738782168	0.294166142808597	Thyroid hormone signaling pathway: TBC1D4
hsa05200__204	0.211577199685763	UP	1.24991701851411	0.296019030684698	Pathways in cancer: TGFB1*
hsa05032__4	0.212072502899475	DOWN	-1.24856356207825	0.29649124475306	Morphine addiction: ADCY1
hsa04068__60	0.213065621594589	DOWN	-1.24585664920653	0.297658217826195	FoxO signaling pathway: RAG1
hsa04611__92	0.213563438083565	UP	1.24450319277068	0.297910690541216	Platelet activation: RHOA*
hsa05200__195	0.213563438083565	DOWN	-1.24450319277068	0.297910690541216	Pathways in cancer: BIRC8
hsa04010__134	0.216567968384677	UP	1.23638245415553	0.301430527848006	MAPK signaling pathway: ATF4*
hsa05219__19	0.216567968384677	DOWN	-1.23638245415553	0.301430527848006	Bladder cancer: TP53
hsa05223__21	0.216567968384677	DOWN	-1.23638245415553	0.301430527848006	Non-small cell lung cancer: FOXO3*
hsa03320__32	0.217071666593695	DOWN	-1.23502899771968	0.301907965602925	PPAR signaling pathway: FABP3
hsa04024__25	0.219094886268247	UP	1.22961517197625	0.304496517232276	cAMP signaling pathway: CFTR
hsa04310__14	0.220111558906282	DOWN	-1.22690825910453	0.305683384467778	Wnt signaling pathway: PRKCA
hsa05161__26	0.220621162583817	UP	1.22555480266868	0.305938866785971	Hepatitis B: MMP9
hsa05164__99	0.220621162583817	DOWN	-1.22555480266868	0.305938866785971	Influenza A: FDPS
hsa05152__94	0.222668037257796	UP	1.22014097692525	0.308549588501032	Tuberculosis: CAMP
hsa04713__56	0.22369655704391	DOWN	-1.21743406405353	0.309746374860359	Circadian entrainment: KCNJ3
hsa04919__18	0.225245700052064	UP	1.21337369474596	0.311432428548807	Thyroid hormone signaling pathway: STAT1
hsa05212__29	0.225245700052064	UP	1.21337369474596	0.311432428548807	Pancreatic cancer: VEGFA
hsa04010__63	0.226802489836983	UP	1.20931332543839	0.313354322355655	MAPK signaling pathway: MAX
hsa04012__43	0.229414164692499	UP	1.2025460432591	0.316729768888469	ErbB signaling pathway: PTK2
hsa04961__20	0.23046461940449	UP	1.19983913038739	0.317946416931745	Endocrine and other factor-regulated calcium reabsorption: CALB1*
hsa04919__30	0.233106352877826	DOWN	-1.1930718482081	0.321354979499218	Thyroid hormone signaling pathway: MYH6
hsa05120__20	0.235234998978017	UP	1.18765802246467	0.324051732463118	Epithelial cell signaling in Helicobacter pylori infection: CXCL8
hsa04670__14	0.235769303711955	UP	1.18630456602882	0.324549832728765	Leukocyte transendothelial migration: SIPA1
hsa04933__23	0.236304466530532	DOWN	-1.18495110959296	0.325048384048953	AGE-RAGE signaling pathway in diabetic complications: F3
hsa04380__32	0.237377368003732	DOWN	-1.18224419672125	0.326285350752752	Osteoclast differentiation: AKT3
hsa05321__123	0.237915107443135	DOWN	-1.18089074028539	0.326785443629862	Inflammatory bowel disease (IBD): IL5*
hsa04022__63	0.238993165670574	DOWN	-1.17818382741367	0.328026412195039	cGMP-PKG signaling pathway: C00575
hsa04668__20	0.239533485228223	DOWN	-1.17683037097782	0.32828841629747	TNF signaling pathway: IKBKG
hsa05145__11	0.239533485228223	DOWN	-1.17683037097782	0.32828841629747	Toxoplasmosis: MAPK14
hsa04550__9	0.242248002618955	UP	1.17006308879853	0.331042906851648	Signaling pathways regulating pluripotency of stem cells: HNF1A
hsa04921__76	0.242248002618955	UP	1.17006308879853	0.331042906851648	Oxytocin signaling pathway: CDKN1A
hsa05200__225	0.242248002618955	DOWN	-1.17006308879853	0.331042906851648	Pathways in cancer: PPARD
hsa05221__11	0.242248002618955	DOWN	-1.17006308879853	0.331042906851648	Acute myeloid leukemia: PPARD
hsa03320__58	0.243339845679802	UP	1.16735617592682	0.332051975332133	PPAR signaling pathway: CYP8B1
hsa04722__70	0.243339845679802	UP	1.16735617592682	0.332051975332133	Neurotrophin signaling pathway: ZNF274
hsa04726__71	0.243887062128776	DOWN	-1.16600271949096	0.332557176879514	Serotonergic synapse: CACNA1A
hsa05162__25 70	0.245533895467249	UP	1.16194235018339	0.334317528683305	Measles: IFNAR1 GNB2L1
hsa05212__8	0.245533895467249	UP	1.16194235018339	0.334317528683305	Pancreatic cancer: NFKB1
hsa04921__23	0.246636107898254	UP	1.15923543731167	0.335332305890607	Oxytocin signaling pathway: C00219
hsa05160__71	0.246636107898254	DOWN	-1.15923543731167	0.335332305890607	Hepatitis C: MAPK8
hsa04728__64	0.247188512225359	DOWN	-1.15788198087582	0.335840357535394	Dopaminergic synapse: SCN1A
hsa03320__30	0.247741782420744	DOWN	-1.15652852443996	0.336348850555331	PPAR signaling pathway: LPL
hsa05120__18	0.248295918826524	UP	1.1551750680041	0.336857784458511	Epithelial cell signaling in Helicobacter pylori infection: CCL5
hsa04750__59	0.249406791624525	DOWN	-1.15246815513239	0.338120751415932	Inflammatory mediator regulation of TRP channels: TRPV2
hsa04066__5	0.251079605800251	UP	1.14840778582482	0.340143171808703	HIF-1 signaling pathway: VEGFA
hsa04726__72	0.252760233826828	DOWN	-1.14434741651725	0.342173256023495	Serotonergic synapse: KCNJ3
hsa04962__10	0.253322181083753	DOWN	-1.14299396008139	0.342687097376797	Vasopressin-regulated water reabsorption: AQP2
hsa05152__51	0.255013241014888	UP	1.13893359077382	0.3447265322784	Tuberculosis: CASP3
hsa04933__57	0.255578668078842	UP	1.13758013433796	0.345242499870701	AGE-RAGE signaling pathway in diabetic complications: FIGF
hsa04014__68	0.256712134668832	UP	1.13487322146624	0.346524497875528	Ras signaling pathway: RALGDS*
hsa04022__71	0.257849086540513	UP	1.13216630859453	0.347559851943776	cGMP-PKG signaling pathway: PPIF
hsa05218__9	0.257849086540513	DOWN	-1.13216630859453	0.347559851943776	Melanoma: CCND1
hsa04660__44	0.259561054402551	UP	1.12810593928696	0.349616646037558	T cell receptor signaling pathway: PAK4
hsa05132__86	0.261280877229695	UP	1.12404556997939	0.351681066127935	Salmonella infection: MYH9
hsa04211__62	0.262431793391648	UP	1.12133865710767	0.352977336995638	Longevity regulating pathway - mammal: EHMT2
hsa04919__38	0.263586206195916	DOWN	-1.11863174423596	0.354276453105955	Thyroid hormone signaling pathway: TP53
hsa05152__81	0.26532438627302	DOWN	-1.11457137492839	0.356357771127238	Tuberculosis: IFNA1
hsa05220__4	0.267070445626092	UP	1.11051100562082	0.358446690951018	Chronic myeloid leukemia: PTPN11
hsa05200__227	0.268238865938032	DOWN	-1.1078040927491	0.35975790799255	Pathways in cancer: FOXO1
hsa05219__12	0.268824391055573	UP	1.10645063631324	0.360286041935393	Bladder cancer: ERBB2
hsa04152__61	0.269410793135789	UP	1.10509717987739	0.360814597506876	AMPK signaling pathway: RPS6KB1
hsa04350__10	0.270586229132007	UP	1.10239026700567	0.362130715483648	TGF-beta signaling pathway: SMAD4
hsa04350__34	0.271765175793561	DOWN	-1.09968335413396	0.363449655029254	TGF-beta signaling pathway: ROCK1
hsa04961__17	0.274133608350252	UP	1.09426952839053	0.366356365640202	Endocrine and other factor-regulated calcium reabsorption: CALB1
hsa05152__6	0.274727913444556	DOWN	-1.09291607195467	0.366889658395396	Tuberculosis: IL10
hsa05215__46	0.28253396083772	DOWN	-1.07532113828853	0.377046386657725	Prostate cancer: MTOR
hsa04071__89	0.285575940983505	UP	1.06855385610924	0.380565385182983	Sphingolipid signaling pathway: C00533
hsa04810__21 82	0.285575940983505	DOWN	-1.06855385610924	0.380565385182983	Regulation of actin cytoskeleton: CFL1 ACTB
hsa05152__15	0.288639983921224	UP	1.06178657392996	0.384375995597434	Tuberculosis: CTSD
hsa04115__25	0.289255441721001	UP	1.0604331174941	0.384922786822776	p53 signaling pathway: CD82
hsa04066__48	0.291107116098931	DOWN	-1.05637274818653	0.387112718435875	HIF-1 signaling pathway: PFKFB3
hsa04622__11	0.291726108332117	UP	1.05501929175067	0.38766149756439	RIG-I-like receptor signaling pathway: IRF7
hsa04550__25	0.292345984501791	DOWN	-1.05366583531481	0.388210674826054	Signaling pathways regulating pluripotency of stem cells: MAPK1
hsa04064__129	0.29421091786589	UP	1.04960546600724	0.390411239173734	NF-kappa B signaling pathway: PTGS2
hsa04390__5	0.295458628670314	UP	1.04689855313553	0.391790235195145	Hippo signaling pathway: SAV1
hsa04360__40 142	0.296083810979623	DOWN	-1.04554509669967	0.392342370120389	Axon guidance: UNC5D PTPN11
hsa04068__72	0.299853488061467	DOWN	-1.03742435808453	0.396777960610912	FoxO signaling pathway: SMAD2
hsa05200__96	0.299853488061467	UP	1.03742435808453	0.396777960610912	Pathways in cancer: C00416
hsa05219__10	0.301117128694494	DOWN	-1.03471744521281	0.398169658562248	Bladder cancer: EGFR
hsa04726__39	0.301750277204841	UP	1.03336398877696	0.398726280497818	Serotonergic synapse: CACNA1C
hsa04662__6	0.303019231006616	UP	1.03065707590524	0.400121669052307	B cell receptor signaling pathway: NFKB1
hsa04014__65	0.303655036445996	UP	1.02930361946938	0.400398465601423	Ras signaling pathway: MLLT4*
hsa05218__8	0.303655036445996	UP	1.02930361946938	0.400398465601423	Melanoma: CDK4
hsa03320__59	0.306207116706041	DOWN	-1.02388979372596	0.403197738115382	PPAR signaling pathway: NR1H3
hsa04014__27	0.306207116706041	UP	1.02388979372596	0.403197738115382	Ras signaling pathway: ABL1
hsa04961__13	0.307488472785686	DOWN	-1.02118288085424	0.404601428826543	Endocrine and other factor-regulated calcium reabsorption: ATP2B1
hsa04310__13	0.308773373401915	DOWN	-1.01847596798253	0.405723894141398	Wnt signaling pathway: NFATC1
hsa05212__14	0.308773373401915	DOWN	-1.01847596798253	0.405723894141398	Pancreatic cancer: MAPK1
hsa05220__19 41	0.310061818918807	UP	1.01576905511081	0.407132185708203	Chronic myeloid leukemia: SMAD4 SMAD3
hsa05166__26	0.311353809649423	UP	1.0130621422391	0.408543162242505	HTLV-I infection: NFATC1
hsa04970__28	0.31200110269297	DOWN	-1.01170868580324	0.40882157031133	Salivary secretion: AQP5
hsa04660__35	0.312001134553724	DOWN	-1.01170868580324	0.40882157031133	T cell receptor signaling pathway: NFATC1
hsa04921__53	0.314599298378404	DOWN	-1.00629486005981	0.411938732859248	Oxytocin signaling pathway: RGS2
hsa04014__24	0.315251055485897	DOWN	-1.00494140362396	0.41250468889833	Ras signaling pathway: PLD1
hsa04670__18	0.316557213244289	DOWN	-1.00223449075224	0.413350266589822	Leukocyte transendothelial migration: CDH5
hsa04213__61	0.316557229176559	UP	1.00223449075224	0.413350266589822	Longevity regulating pathway - multiple species: ATG5
hsa04912__46	0.316557229176559	DOWN	-1.00223449075224	0.413350266589822	GnRH signaling pathway: JUN
hsa04931__87	0.317866948875882	DOWN	-0.999527577880527	0.414772220095682	Insulin resistance: C00031*
hsa05142__7	0.31983553247976	UP	0.995467208572955	0.417051329305669	Chagas disease (American trypanosomiasis): C1QA
hsa05110__50	0.320496946605992	DOWN	-0.994113752137098	0.417623968566338	Vibrio cholerae infection: ACTB
hsa05169__31	0.321156761809639	UP	0.992760295701241	0.417904124266144	Epstein-Barr virus infection: MYC
hsa05200__52	0.321156761809639	DOWN	-0.992760295701241	0.417904124266144	Pathways in cancer: CDKN1B
hsa05169__11	0.326016986330205	DOWN	-0.929147843215954	0.423934890875056	Epstein-Barr virus infection: HLA-A
hsa04068__48	0.32780286748254	DOWN	-0.979225731342669	0.425962370677519	FoxO signaling pathway: FASLG
hsa04010__88 92	0.328472352290495	DOWN	-0.977872274906812	0.426537353112537	MAPK signaling pathway: ECSIT TRAF6
hsa04666__51	0.329142723139106	UP	0.976518818470955	0.42711269114529	Fc gamma R-mediated phagocytosis: NCF1
hsa04550__67	0.331159151342306	DOWN	-0.972458449163383	0.429432743528084	Signaling pathways regulating pluripotency of stem cells: MYC*
hsa05205__22	0.33250786588079	UP	0.969751536291669	0.430868474583024	Proteoglycans in cancer: PPP1R12A
hsa04360__131	0.333183551659997	DOWN	-0.968398079855812	0.430868474583024	Axon guidance: RAC1****
hsa04662__36	0.333183551659997	DOWN	-0.968398079855812	0.430868474583024	B cell receptor signaling pathway: CD79A
hsa04912__26	0.333183551659997	DOWN	-0.968398079855812	0.430868474583024	GnRH signaling pathway: PLD1
hsa05215__25	0.333860123010967	DOWN	-0.967044623419955	0.431135879660126	Prostate cancer: FOXO1
hsa04726__16	0.33453757985336	DOWN	-0.965691166984098	0.431135879660126	Serotonergic synapse: ITPR1
hsa04726__46	0.33453757985336	DOWN	-0.965691166984098	0.431135879660126	Serotonergic synapse: ITPR1*
hsa05110__12	0.33453757985336	DOWN	-0.965691166984098	0.431135879660126	Vibrio cholerae infection: C00080
hsa05120__35	0.33453757985336	DOWN	-0.965691166984098	0.431135879660126	Epithelial cell signaling in Helicobacter pylori infection: C00080
hsa04024__21	0.335895149674279	DOWN	-0.962984254112383	0.432292456327377	cAMP signaling pathway: AKT3
hsa04620__86	0.335895149674279	DOWN	-0.962984254112383	0.432292456327377	Toll-like receptor signaling pathway: IL12A
hsa05152__77	0.337938143389841	UP	0.958923884804812	0.434624073531492	Tuberculosis: IL12A
hsa04151__100	0.339989101534803	UP	0.95486351549724	0.436962737198287	PI3K-Akt signaling pathway: PRKCA
hsa05166__64	0.340674523630306	UP	0.953510059061383	0.437544381340633	HTLV-I infection: CCNB2
hsa04066__52	0.342048021212972	DOWN	-0.950803146189669	0.438708690688856	HIF-1 signaling pathway: FLT1
hsa05200__184	0.342048021212972	UP	0.950803146189669	0.438708690688856	Pathways in cancer: GLI1
hsa04015__17	0.344114899253883	UP	0.946742776882097	0.441058591881341	Rap1 signaling pathway: ACTB
hsa04530__8	0.344805626538309	UP	0.94538932044624	0.441642653214371	Tight junction: LLGL2
hsa04910__42	0.346189732211901	DOWN	-0.942682407574525	0.443113424268502	Insulin signaling pathway: PCK1
hsa04668__48	0.348272516365329	UP	0.938622038266954	0.445475873553746	TNF signaling pathway: CASP3
hsa04062__44	0.351061923478207	UP	0.933208212523525	0.448738336201055	Chemokine signaling pathway: MAPK1
hsa04071__57	0.35246192198607	DOWN	-0.930501299651811	0.449915727861294	Sphingolipid signaling pathway: BAX
hsa04725__64	0.35246192198607	DOWN	-0.930501299651811	0.449915727861294	Cholinergic synapse: KCNJ3
hsa05215__9	0.353163244390403	DOWN	-0.929147843215954	0.450504912565898	Prostate cancer: CDKN1B
hsa04920__37	0.354568534621867	DOWN	-0.926440930344239	0.451990689657047	Adipocytokine signaling pathway: IRS1
hsa04910__12	0.356683080788365	DOWN	-0.922380561036668	0.454070127914185	Insulin signaling pathway: FASN
hsa04931__47	0.356683080788365	DOWN	-0.922380561036668	0.454070127914185	Insulin resistance: AKT2*
hsa04722__35	0.357389691641395	DOWN	-0.921027104600811	0.454354012580637	Neurotrophin signaling pathway: FOXO3
hsa04917__65	0.357389691641395	DOWN	-0.921027104600811	0.454354012580637	Prolactin signaling pathway: CYP17A1
hsa04726__64	0.363788797952787	UP	0.908845996678096	0.462176572923115	Serotonergic synapse: CASP3
hsa04210__102	0.36737462570718	UP	0.90207871449881	0.466101905269271	Apoptosis: PIDD1
hsa04723__67	0.36737462570718	UP	0.90207871449881	0.466101905269271	Retrograde endocannabinoid signaling: PRKACA
hsa04620__22	0.369536655780797	UP	0.898018345191238	0.468528593935302	Toll-like receptor signaling pathway: CD86
hsa04210__105	0.370259086549318	DOWN	-0.896664888755381	0.469127999747922	Apoptosis: ACTB
hsa04725__43	0.371706577651383	UP	0.893957975883667	0.470644649196057	Cholinergic synapse: CREB3
hsa04115__18	0.372431637455593	UP	0.89260451944781	0.471245149346168	p53 signaling pathway: CCNG1
hsa04662__16	0.373884384220538	UP	0.889897606576095	0.472129541633328	B cell receptor signaling pathway: VAV3
hsa04917__45	0.373884384220538	DOWN	-0.889897606576095	0.472129541633328	Prolactin signaling pathway: SLC2A2
hsa05133__27	0.373884384220538	DOWN	-0.889897606576095	0.472129541633328	Pertussis: IRF3
hsa04380__68	0.374612070630729	DOWN	-0.888544150140238	0.472413476990027	Osteoclast differentiation: TGFBR1
hsa05162__58	0.374612070630729	UP	0.888544150140238	0.472413476990027	Measles: STAT3
hsa04024__93	0.376800378594516	DOWN	-0.884483780832667	0.474185700036873	cAMP signaling pathway: ORAI1
hsa04062__8 41	0.376800378594516	UP	0.884483780832667	0.474185700036873	Chemokine signaling pathway: PXN PTK2B
hsa05133__96	0.376800378594516	UP	0.884483780832667	0.474185700036873	Pertussis: IL1B
hsa04024__123	0.377531563201257	DOWN	-0.883130324396809	0.474185700036873	cAMP signaling pathway: PAK1
hsa04340__17	0.377531563201257	DOWN	-0.883130324396809	0.474185700036873	Hedgehog signaling pathway: SMO
hsa05205__142	0.377531563201257	DOWN	-0.883130324396809	0.474185700036873	Proteoglycans in cancer: CTNNB1
hsa04024__107 64	0.378996553579605	DOWN	-0.880423411525095	0.475390203054791	cAMP signaling pathway: NFKBIA NFKB1
hsa04660__40 41	0.378996553579605	DOWN	-0.880423411525095	0.475390203054791	T cell receptor signaling pathway: LAT GRAP2
hsa04010__87	0.379730358750981	UP	0.879069955089238	0.475992891322944	MAPK signaling pathway: STK3
hsa05100__15	0.38120058753086	UP	0.876363042217524	0.477517269313657	Bacterial invasion of epithelial cells: CTNNA1
hsa04360__29	0.382674305482289	DOWN	-0.873656129345809	0.479043984011473	Axon guidance: RASA1
hsa04151__97	0.385632198668593	UP	0.868242303602381	0.482425367042801	PI3K-Akt signaling pathway: MCL1
hsa04015__67	0.386373848653904	UP	0.866888847166523	0.483031577924608	Rap1 signaling pathway: AKT3
hsa05130__9	0.387116368644853	UP	0.865535390730666	0.48363806960351	Pathogenic Escherichia coli infection: TLR4
hsa05205__158	0.387859758300242	UP	0.864181934294809	0.48424484109379	Proteoglycans in cancer: PDCD4
hsa04360__101 103	0.388604017275281	UP	0.862828477858952	0.484530158235072	Axon guidance: DPYSL2 DPYSL5
hsa04660__41 46	0.388604017275281	DOWN	-0.862828477858952	0.484530158235072	T cell receptor signaling pathway: GRAP2 LCP2
hsa04921__28	0.389349145221595	DOWN	-0.861475021423095	0.485137296996935	Oxytocin signaling pathway: EEF2
hsa05166__74	0.391589739350511	UP	0.857414652115523	0.487605778820153	HTLV-I infection: NFKB1
hsa04510__19 23	0.39233833962627	UP	0.856061195679666	0.488214397455472	Focal adhesion: VCL TLN1
hsa04723__7	0.396094341183577	UP	0.84929391350038	0.49256205630969	Retrograde endocannabinoid signaling: ITPR1
hsa04510__19 26	0.396848138890489	UP	0.847940457064523	0.4928470938369	Focal adhesion: VCL ACTN4
hsa05231__50	0.396848138890489	DOWN	-0.847940457064523	0.4928470938369	Choline metabolism in cancer: WASF2
hsa04024__2	0.39835832861734	UP	0.845233544192808	0.494395838488759	cAMP signaling pathway: CACNA1C
hsa04213__55	0.404433619731572	UP	0.834405892705951	0.501604469620874	Longevity regulating pathway - multiple species: CRYAB
hsa04071__68	0.407491938315442	UP	0.828992066962522	0.505064216421316	Sphingolipid signaling pathway: NFKB1
hsa04340__51	0.408258666776009	DOWN	-0.827638610526665	0.50568097222948	Hedgehog signaling pathway: CCND1*
hsa04064__128	0.409026253882984	UP	0.826285154090808	0.506297978291256	NF-kappa B signaling pathway: IL1B*
hsa04922__17	0.409794699190278	DOWN	-0.824931697654951	0.506581736696403	Glucagon signaling pathway: PKM
hsa05134__9	0.409794699190278	UP	0.824931697654951	0.506581736696403	Legionellosis: CASP7
hsa05142__49	0.41133416260324	UP	0.822224784783236	0.508150487528921	Chagas disease (American trypanosomiasis): ADCY1
hsa04520__58	0.41312789017235	DOWN	-0.810043676860522	0.509336790301389	Adherens junction: CDH1*
hsa04014__35	0.413649782863182	UP	0.818164415475665	0.509336790301389	Ras signaling pathway: NFKB1
hsa04210__114	0.413649782863182	DOWN	-0.818164415475665	0.509336790301389	Apoptosis: HRK
hsa04662__29	0.413649782863182	UP	0.818164415475665	0.509336790301389	B cell receptor signaling pathway: RAC1
hsa05205__236	0.413649782863182	UP	0.818164415475665	0.509336790301389	Proteoglycans in cancer: ITGAV
hsa04350__50	0.414423367800297	DOWN	-0.816810959039808	0.509955146101348	TGF-beta signaling pathway: AMHR2
hsa04931__77	0.41830398498015	DOWN	-0.810043676860522	0.514393447498497	Insulin resistance: PPP2R4**
hsa04014__55	0.419862374803296	DOWN	-0.807336763988807	0.515972140127791	Ras signaling pathway: MLLT4
hsa04213__71	0.421424048331141	DOWN	-0.804629851117093	0.517552801839355	Longevity regulating pathway - multiple species: SIRT1**
hsa04724__26	0.42298912412005	UP	0.801922938245379	0.519135574279278	Glutamatergic synapse: PRKACA
hsa04668__116	0.423772936589487	UP	0.800569481809522	0.519758059955383	TNF signaling pathway: PGAM5
hsa04210__86	0.426916671560574	DOWN	-0.795155656066093	0.523272293452263	Apoptosis: BCL2L11
hsa04917__40	0.427704723952845	DOWN	-0.793802199630236	0.523567873014265	Prolactin signaling pathway: TH
hsa05166__33	0.42771510648052	DOWN	-0.769439983784806	0.523567873014265	HTLV-I infection: HLA-A
hsa05200__75	0.428493622742524	UP	0.792448743194379	0.524179373133596	Pathways in cancer: MAPK8
hsa04390__52	0.430865392101337	DOWN	-0.788388373886807	0.526053327978175	Hippo signaling pathway: ITGB2
hsa05205__150	0.430865392101337	UP	0.788388373886807	0.526053327978175	Proteoglycans in cancer: PRKCA
hsa05211__45	0.430865392101337	DOWN	-0.788388373886807	0.526053327978175	Renal cell carcinoma: ETS1
hsa04919__31	0.438826079529612	UP	0.774853809528235	0.535424807426065	Thyroid hormone signaling pathway: ATP2A2
hsa05152__82	0.448489534476672	DOWN	-0.758612332297949	0.54686037331711	Tuberculosis: IL6
hsa04370__28	0.450924142538395	DOWN	-0.754551962990378	0.549116308379549	VEGF signaling pathway: SHC2
hsa04728__24	0.450924142538395	UP	0.754551962990378	0.549116308379549	Dopaminergic synapse: SLC6A3
hsa04064__97	0.45255136219349	UP	0.751845050118663	0.550384472208135	NF-kappa B signaling pathway: PLCG2
hsa04930__8	0.45255136219349	DOWN	-0.751845050118663	0.550384472208135	Type II diabetes mellitus: C00022
hsa05160__58	0.454998400168935	UP	0.747784680811092	0.552645115654446	Hepatitis C: EIF3E
hsa05216__11	0.454998400168935	UP	0.747784680811092	0.552645115654446	Thyroid cancer: MYC
hsa04010__61	0.455815732473289	UP	0.746431224375234	0.553280207569322	MAPK signaling pathway: ATF4
hsa04066__53	0.456633890165272	DOWN	-0.745077767939377	0.553915480710488	HIF-1 signaling pathway: EGF*
hsa04014__62	0.459914761419522	DOWN	-0.739663942195949	0.557535378520826	Ras signaling pathway: RASSF5
hsa05032__25	0.460737035974839	DOWN	-0.738310485760091	0.558172076464682	Morphine addiction: C00575*
hsa04915__40	0.461560131861996	UP	0.736957029324234	0.558449122838821	Estrogen signaling pathway: CREB3**
hsa05169__103	0.461560131861996	UP	0.736957029324234	0.558449122838821	Epstein-Barr virus infection: NFKB1*
hsa05134__6	0.469004839891783	UP	0.72477592140152	0.567091437681249	Legionellosis: IL1B
hsa04520__44 49	0.470668194855684	UP	0.722069008529805	0.568736680471916	Adherens junction: ACTB VCL
hsa05032__37	0.471501091934263	DOWN	-0.720715552093948	0.569376961275373	Morphine addiction: KCNJ3
hsa04623__25	0.47316932161857	UP	0.718008639222234	0.57102450566557	Cytosolic DNA-sensing pathway: NFKB1*
hsa04213__62	0.474004652746777	DOWN	-0.716655182786377	0.571665431650317	Longevity regulating pathway - multiple species: CAT*
hsa04510__24 69	0.477354068423356	UP	0.711241357042948	0.575335660402492	Focal adhesion: ZYX ACTB
hsa04024__60	0.478193441365839	UP	0.709887900607091	0.575977869440007	cAMP signaling pathway: PDE3A
hsa04152__89	0.479874604752533	UP	0.707180987735376	0.577632531921852	AMPK signaling pathway: CFTR
hsa04151__24	0.481558986346915	DOWN	-0.704474074863662	0.579288947084414	PI3K-Akt signaling pathway: MYC
hsa04151__36	0.48493737927923	DOWN	-0.699060249120233	0.582979741308812	PI3K-Akt signaling pathway: PCK1
hsa05200__192	0.485783979125204	DOWN	-0.697706792684376	0.583624102798119	Pathways in cancer: PTGS2
hsa04630__34	0.489178361083744	UP	0.692292966940947	0.587326607333135	Jak-STAT signaling pathway: AOX1
hsa05211__22	0.490880330323578	DOWN	-0.689586054069233	0.588993704136656	Renal cell carcinoma: TGFA
hsa04623__17	0.492585476384707	UP	0.686879141197519	0.589909566683789	Cytosolic DNA-sensing pathway: NFKB1
hsa04933__25	0.492585476384707	DOWN	-0.686879141197519	0.589909566683789	AGE-RAGE signaling pathway in diabetic complications: IL1A
hsa05016__22 9	0.492585476384707	DOWN	-0.686879141197519	0.589909566683789	Huntington's disease: DLG4 HTT
hsa04015__30	0.49857840942496	UP	0.677404946146518	0.596326436225016	Rap1 signaling pathway: ITGAL
hsa05166__53 146	0.49857840942496	DOWN	-0.677404946146518	0.596326436225016	HTLV-I infection: CREB1 CRTC2
hsa04933__63	0.503745900255438	UP	0.669284207531375	0.602123757366392	AGE-RAGE signaling pathway in diabetic complications: SELE
hsa05160__56	0.504609889035947	DOWN	-0.667930751095518	0.60277303337479	Hepatitis C: MAPK1
hsa05223__14	0.505474658436394	UP	0.666577294659661	0.603422416265555	Non-small cell lung cancer: CCND1
hsa05231__21	0.50720653557242	DOWN	-0.663870381787946	0.605105447835287	Choline metabolism in cancer: PCYT1A
hsa04742__37	0.508073529811199	DOWN	-0.662516925352089	0.605755179260941	Taste transduction: P2RY4
hsa04742__48	0.50894152457765	DOWN	-0.661163468916232	0.606405278808754	Taste transduction: GABBR1
hsa05016__55	0.50981018380092	DOWN	-0.659810012480375	0.60705534560325	Huntington's disease: TGM2
hsa05140__62	0.511549827196274	UP	0.657103099608661	0.608741054655984	Leishmaniasis: C00584
hsa05031__8	0.512420781791237	DOWN	-0.655749643172803	0.609391549990971	Amphetamine addiction: DRD1
hsa03320__8	0.513292564490885	DOWN	-0.654396186736946	0.610042206627687	PPAR signaling pathway: GK
hsa05200__188	0.517662895553192	DOWN	-0.64762890455766	0.614847396172217	Pathways in cancer: KLK3
hsa04810__35 81 80	0.518539266579896	DOWN	-0.646275448121803	0.615499230513977	Regulation of actin cytoskeleton: MYL12B MYH9 ACTB
hsa05210__16	0.523813547836157	DOWN	-0.63815470950666	0.621367207313218	Colorectal cancer: MAPK8
hsa03320__66	0.525577735052835	UP	0.635447796634946	0.623066601996389	PPAR signaling pathway: UCP1
hsa05200__197	0.529115203594221	UP	0.630033970891517	0.626864733640316	Pathways in cancer: CCND1**
hsa04660__43	0.530001459665912	UP	0.62868051445566	0.627519056529457	T cell receptor signaling pathway: RHOA
hsa04730__8	0.530888455827589	DOWN	-0.627327058019803	0.628173431045365	Long-term depression: GNA13*
hsa04931__40	0.531776231672782	UP	0.625973601583945	0.628827903910105	Insulin resistance: PRKCZ
hsa04621__30 32	0.534444024506662	DOWN	-0.621913232276374	0.63118813453678	NOD-like receptor signaling pathway: PYCARD CASP1
hsa04933__21	0.534444024506662	UP	0.621913232276374	0.63118813453678	AGE-RAGE signaling pathway in diabetic complications: SMAD4
hsa04014__63	0.535334787423064	UP	0.620559775840517	0.63184300601001	Ras signaling pathway: TIAM1*
hsa04917__57	0.5362262979894	DOWN	-0.61920631940466	0.632101137968684	Prolactin signaling pathway: ESR1
hsa04921__67	0.5362262979894	UP	0.61920631940466	0.632101137968684	Oxytocin signaling pathway: RYR1
hsa04530__4 37 11	0.547883508455827	DOWN	-0.601611385738516	0.645033278438909	Tight junction: OCLN TJP3 TJP1
hsa05211__49	0.547883508455827	DOWN	-0.601611385738516	0.645033278438909	Renal cell carcinoma: TGFA*
hsa03320__56	0.549687981248109	UP	0.598904472866802	0.646347757675343	PPAR signaling pathway: FADS2
hsa04919__101	0.549687981248109	UP	0.598904472866802	0.646347757675343	Thyroid hormone signaling pathway: NOTCH1
hsa04062__42	0.550591314840433	DOWN	-0.597551016430945	0.647005053524186	Chemokine signaling pathway: PAK1
hsa04976__38	0.552400171097929	UP	0.59484410355923	0.648724950933131	Bile secretion: ABCC2
hsa04620__40	0.554211938985308	UP	0.592137190687516	0.650040095726213	Toll-like receptor signaling pathway: CCL5
hsa05164__77	0.554211938985308	UP	0.592137190687516	0.650040095726213	Influenza A: CASP9
hsa04510__20 4 5	0.556935031272377	DOWN	-0.588076821379944	0.652419528529175	Focal adhesion: VASP ITGB1 ITGA11
hsa05205__45 46	0.556935031272377	DOWN	-0.588076821379944	0.652419528529175	Proteoglycans in cancer: PAK1 FLNA
hsa04066__58	0.557844175152908	DOWN	-0.586723364944087	0.653077386362813	HIF-1 signaling pathway: EDN1
hsa05110__13	0.559664613118156	DOWN	-0.584016452072373	0.654800627676846	Vibrio cholerae infection: C00238
hsa04742__55	0.560575724364676	UP	0.582662995636516	0.655458485427023	Taste transduction: P2RX3
hsa04330__12	0.561487953786508	DOWN	-0.581309539200659	0.656116831570179	Notch signaling pathway: HES1
hsa05162__62	0.562400693718424	UP	0.579956082764801	0.656774955560546	Measles: IL12A
hsa05205__121	0.566975109494479	UP	0.573188800585515	0.66170573337896	Proteoglycans in cancer: PLAUR
hsa04921__80	0.569728291467313	UP	0.569128431277944	0.664506182288691	Oxytocin signaling pathway: KCNJ2
hsa05169__64	0.572487835455711	UP	0.565068061970372	0.667310572469777	Epstein-Barr virus infection: NFKB2
hsa04915__28	0.575253710560745	DOWN	-0.561007692662801	0.670118860597421	Estrogen signaling pathway: KCNJ3
hsa05166__99	0.578025885603604	UP	0.556947323355229	0.672931003128359	HTLV-I infection: JUN
hsa04914__15	0.578951338508276	UP	0.555593866919372	0.67359106195483	Progesterone-mediated oocyte maturation: ANAPC10
hsa05134__72	0.580804329126494	DOWN	-0.552886954047658	0.675328796057353	Legionellosis: IL12A
hsa04360__111	0.582660091636717	DOWN	-0.550180041175943	0.677067601846252	Axon guidance: RHOA***
hsa04650__16	0.583589009393565	UP	0.548826584740086	0.67730929502811	Natural killer cell mediated cytotoxicity: PRKCA
hsa04910__20	0.583589009393565	DOWN	-0.548826584740086	0.67730929502811	Insulin signaling pathway: PKLR
hsa04151__4	0.586379894391858	DOWN	-0.544766215432515	0.680128284915	PI3K-Akt signaling pathway: RPS6
hsa05161__195	0.587311562647551	DOWN	-0.543412758996658	0.680788665154071	Hepatitis B: IL6
hsa04370__16	0.593852342200681	DOWN	-0.533938563945657	0.687946085693638	VEGF signaling pathway: HSPB1
hsa05210__9 11	0.594789453508196	UP	0.5325851075098	0.688607136871165	Colorectal cancer: SMAD2 SMAD4
hsa05133__30	0.596665699539489	UP	0.529878194638086	0.689318280503658	Pertussis: NOS2
hsa04020__18	0.597604807669019	DOWN	-0.528524738202229	0.689318280503658	Calcium signaling pathway: C00002
hsa04020__17	0.597604807669019	DOWN	-0.528524738202229	0.689318280503658	Calcium signaling pathway: C00004
hsa04020__15	0.597604807669019	DOWN	-0.528524738202229	0.689318280503658	Calcium signaling pathway: C13051
hsa04210__83	0.597604831793752	DOWN	-0.528524738202229	0.689318280503658	Apoptosis: TP53*
hsa04810__82 83	0.597604831793752	DOWN	-0.528524738202229	0.689318280503658	Regulation of actin cytoskeleton: ACTB ARPC5
hsa05152__129	0.604197480591365	UP	0.519050543151228	0.696495132534463	Tuberculosis: IFNB1
hsa04066__47	0.606087075027395	DOWN	-0.516343630279514	0.698050641966689	HIF-1 signaling pathway: PGK1
hsa04210__70	0.607032862678856	DOWN	-0.514990173843657	0.698050641966689	Apoptosis: CFLAR*
hsa05200__121 122	0.607032862678856	UP	0.514990173843657	0.698050641966689	Pathways in cancer: SMAD2 SMAD4
hsa05212__38 39	0.607032862678856	UP	0.514990173843657	0.698050641966689	Pancreatic cancer: SMAD2 SMAD4
hsa04932__14	0.609874172080646	DOWN	-0.510929804536085	0.700460616955706	Non-alcoholic fatty liver disease (NAFLD): PKLR
hsa05200__219	0.609874172080646	DOWN	-0.510929804536085	0.700460616955706	Pathways in cancer: MYC**
hsa04010__62	0.613671745128543	UP	0.505515978792657	0.703961666115099	MAPK signaling pathway: MEF2C
hsa04932__95	0.613671745128543	DOWN	-0.505515978792657	0.703961666115099	Non-alcoholic fatty liver disease (NAFLD): IL1A
hsa04340__26	0.61843331734159	UP	0.498748696613371	0.7089909721079	Hedgehog signaling pathway: PTCH1**
hsa05217__3	0.622254157980946	UP	0.493334870869942	0.712728791794734	Basal cell carcinoma: GLI1
hsa04066__59	0.623210965896087	UP	0.491981414434085	0.712728791794734	HIF-1 signaling pathway: NOS2
hsa05214__27	0.623210965896087	UP	0.491981414434085	0.712728791794734	Glioma: MTOR
hsa05214__48	0.623210965896087	UP	0.491981414434085	0.712728791794734	Glioma: MTOR*
hsa05200__193	0.624168410261217	UP	0.490627957998228	0.713389563796123	Pathways in cancer: NOS2
hsa04970__12	0.628004355768417	UP	0.485214132254799	0.716901885473097	Salivary secretion: BEST2
hsa04390__13	0.628004525539498	UP	0.485214132254799	0.716901885473097	Hippo signaling pathway: BIRC5
hsa04211__38	0.631850716904901	UP	0.47980030651137	0.720417170548732	Longevity regulating pathway - mammal: BAX
hsa04810__32	0.631850716904901	UP	0.47980030651137	0.720417170548732	Regulation of actin cytoskeleton: PXN
hsa05152__13	0.633777564102676	UP	0.477093393639656	0.722175890205536	Tuberculosis: LAMP1
hsa04360__18	0.634741920821682	UP	0.475739937203799	0.722836405590266	Axon guidance: PTK2
hsa04010__12	0.635706897799513	DOWN	-0.474386480767941	0.723496826750626	MAPK signaling pathway: PLA2G4B
hsa05130__28	0.637638707048975	DOWN	-0.471679567896227	0.724817380849984	Pathogenic Escherichia coli infection: ROCK1
hsa05231__39	0.637638707048975	DOWN	-0.471679567896227	0.724817380849984	Choline metabolism in cancer: EIF4EBP1
hsa04621__4 7 8	0.639572980854278	DOWN	-0.468972655024513	0.726576560474721	NOD-like receptor signaling pathway: IKBKG CHUK IKBKB
hsa05231__38	0.640541038515152	DOWN	-0.467619198588655	0.727236623184273	Choline metabolism in cancer: RPS6KB1
hsa04152__24	0.643448877894603	UP	0.463558829281084	0.730096885002391	AMPK signaling pathway: SIRT1
hsa05211__2	0.644419375180729	UP	0.462205372845227	0.730756792978026	Renal cell carcinoma: TGFB1
hsa04660__56	0.645390478885925	UP	0.46085191640937	0.731416592175304	T cell receptor signaling pathway: CD3E
hsa05200__196	0.646362187609097	UP	0.459498459973512	0.732076281204034	Pathways in cancer: TRAF1
hsa04211__57	0.649280929829167	UP	0.455438090665941	0.734939076595786	Longevity regulating pathway - mammal: ATG5
hsa04022__58	0.652205066475514	UP	0.451377721358369	0.736917209806068	cGMP-PKG signaling pathway: MYH7
hsa04024__34	0.652205066475514	DOWN	-0.451377721358369	0.736917209806068	cAMP signaling pathway: ATP2B1
hsa04210__50	0.652205066475514	UP	0.451377721358369	0.736917209806068	Apoptosis: SPTA1
hsa04310__32	0.655134559220426	DOWN	-0.447317352050798	0.739782353831238	Wnt signaling pathway: PPARD
hsa04668__128	0.659048814548169	UP	0.441903526307369	0.743755388910517	TNF signaling pathway: CHUK*
hsa04064__94	0.665921230991562	UP	0.432429331256369	0.750609473925102	NF-kappa B signaling pathway: BCL2L1*
hsa04650__25	0.665921230991562	DOWN	-0.432429331256369	0.750609473925102	Natural killer cell mediated cytotoxicity: SH2D1B
hsa04211__51	0.666905316018229	DOWN	-0.431075874820512	0.751268038847873	Longevity regulating pathway - mammal: NFKB1
hsa04210__52	0.670847375628702	DOWN	-0.425662049077083	0.755255972921709	Apoptosis: PARP2
hsa05016__60	0.673809884472228	DOWN	-0.421601679769511	0.757683287207251	Huntington's disease: CASP3*
hsa05134__35	0.673809884472228	DOWN	-0.421601679769511	0.757683287207251	Legionellosis: CASP3
hsa04540__22	0.678758600644928	DOWN	-0.414834397590226	0.762791513523816	Gap junction: C00547
hsa04014__67	0.680742042597855	UP	0.412127484718511	0.764563238518452	Ras signaling pathway: RAPGEF5*
hsa05205__324	0.681734573209446	DOWN	-0.410774028282654	0.765220587252419	Proteoglycans in cancer: KDR*
hsa04015__100 101 48	0.682727654876825	DOWN	-0.409420571846797	0.765420801619066	Rap1 signaling pathway: PRKCI PARD6A PARD3
hsa04750__90	0.682727654876825	DOWN	-0.409420571846797	0.765420801619066	Inflammatory mediator regulation of TRP channels: C01245**
hsa04662__35	0.683721286085761	UP	0.40806711541094	0.766077696216544	B cell receptor signaling pathway: CD79B
hsa04010__120	0.686705461776857	UP	0.404006746103368	0.768962790630938	MAPK signaling pathway: NFATC1
hsa03320__27	0.688697632056441	DOWN	-0.401299833231654	0.770275506329794	PPAR signaling pathway: CPT1C
hsa04950__16	0.688697632056441	UP	0.401299833231654	0.770275506329794	Maturity onset diabetes of the young: PAX4
hsa05200__48	0.68969452855663	DOWN	-0.399946376795797	0.770931599737007	Pathways in cancer: MTOR
hsa04919__91	0.691689936607552	UP	0.397239463924082	0.772702372702491	Thyroid hormone signaling pathway: PFKP
hsa04725__25	0.692688445081777	UP	0.395886007488225	0.773358044152501	Cholinergic synapse: CACNA1A
hsa05132__20	0.693687487799518	DOWN	-0.394532551052368	0.774013533001956	Salmonella infection: ACTB
hsa05161__126	0.695687169781871	DOWN	-0.391825638180653	0.775784090219666	Hepatitis B: MYC*
hsa04066__49	0.697688970159537	DOWN	-0.389118725308939	0.777554908024775	HIF-1 signaling pathway: EPO
hsa04668__141	0.698690660861062	UP	0.387765268873082	0.77820969280257	TNF signaling pathway: JUN*
hsa04917__44	0.69969287649325	DOWN	-0.386411812437225	0.778864286096455	Prolactin signaling pathway: PRLR**
hsa05200__198	0.700695615494325	UP	0.385058356001368	0.77951868650908	Pathways in cancer: BCL2L1*
hsa05133__59	0.702702657342372	DOWN	-0.382351443129653	0.780365421481274	Pertussis: C3
hsa05200__214	0.702702657342372	UP	0.382351443129653	0.780365421481274	Pathways in cancer: CSF3R
hsa05220__15	0.702702657342372	DOWN	-0.382351443129653	0.780365421481274	Chronic myeloid leukemia: MYC
hsa04668__36	0.704711773856452	UP	0.379644530257939	0.781672622831331	TNF signaling pathway: CREB3
hsa04950__30	0.704711773856452	DOWN	-0.379644530257939	0.781672622831331	Maturity onset diabetes of the young: PAX6*
hsa05166__39	0.708736180470995	DOWN	-0.37423070451451	0.78493710858168	HTLV-I infection: RRAS2
hsa04727__26	0.709743559063478	UP	0.372877248078653	0.78493710858168	GABAergic synapse: KCNJ6
hsa05032__81	0.709743559063478	UP	0.372877248078653	0.78493710858168	Morphine addiction: KCNJ6
hsa05032__91	0.709743559063478	UP	0.372877248078653	0.78493710858168	Morphine addiction: KCNJ6**
hsa05032__85	0.709743559063478	UP	0.372877248078653	0.78493710858168	Morphine addiction: KCNJ6*
hsa04621__6	0.71276873408433	DOWN	-0.368816878771081	0.787355938474107	NOD-like receptor signaling pathway: NFKB1
hsa05168__9	0.71276873408433	DOWN	-0.368816878771081	0.787355938474107	Herpes simplex infection: NFKB1
hsa05014__13	0.71680933275981	DOWN	-0.363403053027653	0.790889451706214	Amyotrophic lateral sclerosis (ALS): CASP3
hsa05110__17	0.71680933275981	DOWN	-0.363403053027653	0.790889451706214	Vibrio cholerae infection: C00698*
hsa05164__23	0.719844999636058	UP	0.359342683720081	0.793772743143282	Influenza A: IRF3
hsa04152__52	0.724914254181201	UP	0.352575401540795	0.798893773376233	AMPK signaling pathway: PCK1
hsa04621__34 35	0.725929561959467	DOWN	-0.351221945104938	0.799075364336168	NOD-like receptor signaling pathway: CASP1 PYCARD
hsa05161__29	0.725929561959467	DOWN	-0.351221945104938	0.799075364336168	Hepatitis B: NFKB1
hsa05200__213	0.72694535156237	UP	0.349868488669081	0.799725009125113	Pathways in cancer: CSF2RA
hsa05152__78	0.731013295522533	UP	0.344454662925652	0.803729656106987	Tuberculosis: IL1A
hsa05221__35	0.73406923238298	UP	0.340394293618081	0.806617595115567	Acute myeloid leukemia: EIF4EBP1
hsa05100__55	0.7350888175835	UP	0.339040837182223	0.807265861039974	Bacterial invasion of epithelial cells: ACTB*
hsa04668__47	0.738150368783832	UP	0.334980467874652	0.809681577901238	TNF signaling pathway: CASP7
hsa05152__23	0.738150368783832	DOWN	-0.334980467874652	0.809681577901238	Tuberculosis: PPP3CA
hsa05169__32	0.747359793670394	UP	0.322799359951937	0.81882743574733	Epstein-Barr virus infection: CR2
hsa05223__7	0.747359793670394	DOWN	-0.322799359951937	0.81882743574733	Non-small cell lung cancer: FOXO3
hsa04012__22	0.750437708534013	UP	0.318738990644366	0.821241965250676	ErbB signaling pathway: EIF4EBP1
hsa04340__14	0.750437708534013	DOWN	-0.318738990644366	0.821241965250676	Hedgehog signaling pathway: PTCH1
hsa04024__44 67	0.752491864338069	UP	0.316032077772651	0.823010601333662	cAMP signaling pathway: CREB3 CREBBP
hsa04370__15	0.753519600933924	UP	0.314678621336794	0.823655224057501	VEGF signaling pathway: PLA2G4B
hsa04917__71	0.754547774398139	DOWN	-0.313325164900937	0.824299574473316	Prolactin signaling pathway: CCND1*
hsa05150__14	0.755576351870864	UP	0.31197170846508	0.824464589847523	Staphylococcus aureus infection: FPR1
hsa04910__9	0.755576383032163	UP	0.31197170846508	0.824464589847523	Insulin signaling pathway: ELK1
hsa04010__118	0.758664802932949	DOWN	-0.307911339157508	0.826874225470425	MAPK signaling pathway: JUN
hsa05213__31	0.758664802932949	DOWN	-0.307911339157508	0.826874225470425	Endometrial cancer: MYC
hsa04727__8	0.76072589413873	DOWN	-0.305204426285794	0.82815988127849	GABAergic synapse: ADCY1
hsa05211__21	0.76072589413873	DOWN	-0.305204426285794	0.82815988127849	Renal cell carcinoma: TGFB1*
hsa04724__65	0.764853079333584	DOWN	-0.299790600542365	0.831689288982427	Glutamatergic synapse: GRM3
hsa04918__10	0.764853161980646	UP	0.299790600542365	0.831689288982427	Thyroid hormone synthesis: TG
hsa04020__16	0.766919311129762	UP	0.297083687670651	0.833131468207686	Calcium signaling pathway: C06124
hsa04211__29	0.767953008480954	DOWN	-0.295730231234794	0.833131468207686	Longevity regulating pathway - mammal: EIF4E
hsa05152__90	0.767953008480954	UP	0.295730231234794	0.833131468207686	Tuberculosis: CR1
hsa05212__27	0.767953008480954	DOWN	-0.295730231234794	0.833131468207686	Pancreatic cancer: BCL2L1*
hsa04062__35 36 37	0.768987118713349	UP	0.294376774798937	0.833771953873274	Chemokine signaling pathway: PARD3 PRKCZ TIAM1
hsa04062__33	0.77002164009678	UP	0.293023318363079	0.833931217142276	Chemokine signaling pathway: WAS
hsa05110__46	0.77002164009678	UP	0.293023318363079	0.833931217142276	Vibrio cholerae infection: PLCG1
hsa04360__82	0.77105657089888	DOWN	-0.291669861927222	0.83409055654519	Axon guidance: ILK
hsa04670__39	0.77105657089888	UP	0.291669861927222	0.83409055654519	Leukocyte transendothelial migration: MAPK14
hsa04010__117	0.7720919093851	DOWN	-0.290316405491365	0.834249969945142	MAPK signaling pathway: JUND
hsa04920__10	0.7720919093851	UP	0.290316405491365	0.834249969945142	Adipocytokine signaling pathway: PCK1
hsa05215__12	0.773127653818712	UP	0.288962949055508	0.834889000876644	Prostate cancer: KLK3
hsa04976__59	0.774163802460821	DOWN	-0.287609492619651	0.835527733959726	Bile secretion: ABCB4
hsa03320__55	0.776237305404154	UP	0.284902579747936	0.836324482141287	PPAR signaling pathway: SCD
hsa05166__83	0.776237305404154	UP	0.284902579747936	0.836324482141287	HTLV-I infection: NFKB2
hsa05200__212	0.776237305404154	DOWN	-0.284902579747936	0.836324482141287	Pathways in cancer: CCND1***
hsa05164__34	0.777274656216821	DOWN	-0.283549123312079	0.836482863133681	Influenza A: IL1B
hsa05321__95	0.777274656216821	UP	0.283549123312079	0.836482863133681	Inflammatory bowel disease (IBD): SMAD2
hsa05100__24	0.779350547786756	UP	0.280842210440365	0.838236794099207	Bacterial invasion of epithelial cells: ACTB
hsa05168__29	0.781428014274867	DOWN	-0.27813529756865	0.839990411225673	Herpes simplex infection: IKBKG
hsa04668__38	0.783507041642136	UP	0.275428384696936	0.841743699968881	TNF signaling pathway: CEBPB
hsa05020__62	0.787669722691194	DOWN	-0.270014558953507	0.845732233678145	Prion diseases: NOTCH1
hsa04917__38	0.791838477958281	UP	0.264600733210079	0.849237728358224	Prolactin signaling pathway: IRF1
hsa05166__65	0.791838477958281	UP	0.264600733210079	0.849237728358224	HTLV-I infection: PTTG2
hsa04620__87	0.793925097975934	DOWN	-0.261893820338364	0.850504708721083	Toll-like receptor signaling pathway: CCL4L1
hsa05200__210	0.793925097975934	DOWN	-0.261893820338364	0.850504708721083	Pathways in cancer: MMP1
hsa04933__52	0.798102751603178	DOWN	-0.256479994594935	0.854492917528417	AGE-RAGE signaling pathway in diabetic complications: FOXO1
hsa05231__18	0.801239797462921	UP	0.252419625287364	0.857363086237374	Choline metabolism in cancer: CHKA
hsa04913__21	0.803332946710778	DOWN	-0.24971271241565	0.858624918583363	Ovarian steroidogenesis: CYP17A1
hsa04913__22	0.803332946710778	DOWN	-0.24971271241565	0.858624918583363	Ovarian steroidogenesis: CYP17A1*
hsa04068__39	0.804380051549098	DOWN	-0.248359255979792	0.859255325105603	FoxO signaling pathway: CCNB3
hsa04917__48	0.805427507464555	DOWN	-0.247005799543935	0.859885390071533	Prolactin signaling pathway: CCND2
hsa04012__25	0.806475312655442	DOWN	-0.245652343108078	0.860026738070134	ErbB signaling pathway: CDKN1B
hsa04950__18	0.806475312655442	UP	0.245652343108078	0.860026738070134	Maturity onset diabetes of the young: SLC2A2
hsa05200__203	0.808571963647286	UP	0.242945430236364	0.861773522230998	Pathways in cancer: TGFA*
hsa04933__61	0.809620805835462	DOWN	-0.241591973800507	0.862402207576436	AGE-RAGE signaling pathway in diabetic complications: MMP2
hsa04014__76	0.811719514550465	DOWN	-0.238885060928792	0.864147857133328	Ras signaling pathway: RALBP1*
hsa05205__34	0.815920978562596	UP	0.233471235185363	0.868128832796783	Proteoglycans in cancer: SLC9A1
hsa05014__53	0.819075560069218	UP	0.229410865877792	0.870992064159627	Amyotrophic lateral sclerosis (ALS): RAB5A
hsa04024__109	0.820127741042403	DOWN	-0.228057409441935	0.871617661435902	cAMP signaling pathway: BDNF
hsa04611__7	0.821180245873901	DOWN	-0.226703953006078	0.871750102823198	Platelet activation: ITPR1
hsa05212__54	0.821180245873901	UP	0.226703953006078	0.871750102823198	Pancreatic cancer: C00416
hsa05145__9	0.825393467178332	UP	0.221290127262649	0.875728020795079	Toxoplasmosis: MAPK1
hsa05012__57	0.82644756383275	DOWN	-0.219936670826792	0.876351564583373	Parkinson's disease: CASP3
hsa05205__451	0.827501973345976	UP	0.218583214390934	0.876974736557862	Proteoglycans in cancer: KDR**
hsa04540__11	0.831722703177244	UP	0.213169388647506	0.880950935326968	Gap junction: C00780
hsa04014__100	0.8327786493626	UP	0.211815932211649	0.881076059770453	Ras signaling pathway: REL
hsa04666__30 44	0.8327786493626	DOWN	-0.211815932211649	0.881076059770453	Fc gamma R-mediated phagocytosis: C04637 GSN
hsa03320__64	0.835948291310751	UP	0.207755562904077	0.883557982984366	PPAR signaling pathway: APOA5
hsa04012__3	0.83700543358817	DOWN	-0.20640210646822	0.883557982984366	ErbB signaling pathway: ELK1
hsa04066__60	0.83700543358817	DOWN	-0.20640210646822	0.883557982984366	HIF-1 signaling pathway: NOS3
hsa04910__26	0.83700543358817	UP	0.20640210646822	0.883557982984366	Insulin signaling pathway: RPS6
hsa04210__10	0.83806287025758	UP	0.205048650032363	0.884177503208306	Apoptosis: BIRC2
hsa05321__92	0.842295523719112	UP	0.199634824288934	0.887766345110917	Inflammatory bowel disease (IBD): IL17F
hsa04622__9 35	0.843354404482696	DOWN	-0.198281367853077	0.887766345110917	RIG-I-like receptor signaling pathway: IRF3 PIN1
hsa04723__10	0.843354404482696	UP	0.198281367853077	0.887766345110917	Retrograde endocannabinoid signaling: CACNA1A
hsa04723__21	0.843354404482696	UP	0.198281367853077	0.887766345110917	Retrograde endocannabinoid signaling: CACNA1A*
hsa05134__69	0.849713571665805	UP	0.190160629237934	0.893959575117607	Legionellosis: IL1B*
hsa05215__22	0.851677396069555	UP	0.186100259930362	0.895189528529726	Prostate cancer: C16038
hsa04976__37	0.85183548537049	UP	0.187453716366219	0.895189528529726	Bile secretion: ABCB11
hsa05152__9	0.852896852801719	DOWN	-0.186100259930362	0.895803905206501	Tuberculosis: TCIRG1
hsa04014__61	0.856082531490994	DOWN	-0.182039890622791	0.898647528866803	Ras signaling pathway: RAP1A
hsa04950__7	0.857144948408038	DOWN	-0.180686434186933	0.899260389759186	Maturity onset diabetes of the young: FOXA3
hsa03320__25	0.858207624198835	UP	0.179332977751076	0.899370956982494	PPAR signaling pathway: EHHADH
hsa05200__207	0.858207624198835	DOWN	-0.179332977751076	0.899370956982494	Pathways in cancer: CDK4
hsa04728__61	0.861397185966269	DOWN	-0.175272608443505	0.902210319080613	Dopaminergic synapse: KCNJ3
hsa04152__62	0.864589009688376	DOWN	-0.171212239135933	0.904544960581548	AMPK signaling pathway: EIF4EBP1
hsa04360__117	0.864589009688376	DOWN	-0.171212239135933	0.904544960581548	Axon guidance: CFL1*
hsa04340__40	0.867783044310148	UP	0.167151869828362	0.907381380221908	Hedgehog signaling pathway: SUFU
hsa04650__119	0.868848204988475	DOWN	-0.165798413392504	0.907989864946242	Natural killer cell mediated cytotoxicity: KLRC4-KLRK1
hsa04917__33	0.872045107870748	UP	0.161738044084933	0.91082421216739	Prolactin signaling pathway: CSN2
hsa04151__109	0.873111209446769	DOWN	-0.160384587649076	0.911431090305822	PI3K-Akt signaling pathway: RXRA
hsa05142__53	0.880580266955209	DOWN	-0.150910392598076	0.918717557806129	Chagas disease (American trypanosomiasis): AKT3
hsa04152__15	0.884853118382261	DOWN	-0.145496566854647	0.922151419545351	AMPK signaling pathway: FOXO1
hsa04621__23	0.884853118382261	DOWN	-0.145496566854647	0.922151419545351	NOD-like receptor signaling pathway: CASP1
hsa04620__34	0.888059962984425	UP	0.141436197547075	0.924980415990984	Toll-like receptor signaling pathway: IL1B
hsa04152__63	0.889129321155747	UP	0.140082741111218	0.925581160361024	AMPK signaling pathway: PPARG
hsa04530__6 11 45	0.891268640933237	DOWN	-0.137375828239504	0.92729444978602	Tight junction: CLDN24 TJP1 TJP2
hsa04062__53	0.892338598695196	DOWN	-0.136022371803647	0.927893872135182	Chemokine signaling pathway: NFKB1
hsa05200__199	0.894479100346897	DOWN	-0.133315458931932	0.929091337507916	Pathways in cancer: BCL2L1**
hsa05220__3	0.894479100346897	DOWN	-0.133315458931932	0.929091337507916	Chronic myeloid leukemia: BCL2L1
hsa04014__37	0.895549640385977	UP	0.131962002496075	0.929689378058149	Ras signaling pathway: FASLG
hsa04151__35	0.898762394230103	UP	0.127901633188503	0.932509408480598	PI3K-Akt signaling pathway: CCND1
hsa04920__12	0.900905136132846	DOWN	-0.125194720316789	0.933701482285827	Adipocytokine signaling pathway: C00165
hsa04742__49	0.900905155606282	UP	0.125194720316789	0.933701482285827	Taste transduction: HTR1A
hsa05010__59	0.903048636165446	DOWN	-0.122487807445075	0.935407049258474	Alzheimer's disease: LRP1
hsa04540__10	0.9041206472607	DOWN	-0.121134351009218	0.936001485511215	Gap junction: C00533
hsa04913__12	0.905192829967996	DOWN	-0.11978089457336	0.936595444664022	Ovarian steroidogenesis: HSD3B1
hsa04071__24	0.911629488286694	DOWN	-0.111660155958217	0.942736273247495	Sphingolipid signaling pathway: PTEN
hsa04961__26	0.912702840253636	DOWN	-0.11030669952236	0.943327082968417	Endocrine and other factor-regulated calcium reabsorption: TRPV5*
hsa04360__81	0.919146228791902	DOWN	-0.102185960907217	0.949464411159969	Axon guidance: FYN*
hsa04520__73	0.921295226560202	DOWN	-0.0994790480355027	0.951161390498143	Adherens junction: PARD3
hsa04014__66	0.924519796133536	DOWN	-0.0954186787279312	0.953966335494187	Ras signaling pathway: RAF1*
hsa04920__9	0.926670201706899	UP	0.0927117658562168	0.955660433044601	Adipocytokine signaling pathway: G6PC
hsa04976__41	0.929896809805291	DOWN	-0.0886513965486452	0.958461933968263	Bile secretion: CYP7A1
hsa04014__54	0.939583339439366	DOWN	-0.0764702886259306	0.966854925961976	Ras signaling pathway: RHOA
hsa04151__2	0.939583339439366	DOWN	-0.0764702886259306	0.966854925961976	PI3K-Akt signaling pathway: EIF4E
hsa04971__52 53	0.939583339439366	DOWN	-0.0764702886259306	0.966854925961976	Gastric acid secretion: EZR ACTB
hsa04064__50	0.942814241513895	DOWN	-0.0724099193183591	0.968588277640573	NF-kappa B signaling pathway: NFKBIA*
hsa05164__35	0.942814241513895	DOWN	-0.0724099193183591	0.968588277640573	Influenza A: IL18
hsa05213__11	0.942814241513895	UP	0.0724099193183591	0.968588277640573	Endometrial cancer: FOXO3
hsa04622__6	0.94604608476722	DOWN	-0.0683495500107876	0.971377373375741	RIG-I-like receptor signaling pathway: NFKB1
hsa04270__65	0.947123551933362	DOWN	-0.0669960935749304	0.971422041600497	Vascular smooth muscle contraction: NPR2
hsa05110__52	0.947123565839335	UP	0.0669960935749304	0.971422041600497	Vibrio cholerae infection: ADCY3
hsa04360__33 134	0.948201143630877	UP	0.0656426371390732	0.97199669879019	Axon guidance: NCK1 PAK4
hsa04152__53	0.950356581509933	UP	0.0629357242673588	0.973144423246411	AMPK signaling pathway: G6PC
hsa05231__34	0.950356581509933	UP	0.0629357242673588	0.973144423246411	Choline metabolism in cancer: PLD1
hsa05133__94	0.953590414571354	DOWN	-0.0588753549597873	0.975923959139202	Pertussis: IL12A
hsa04024__112	0.954668531387234	UP	0.0575218985239301	0.976495465692223	cAMP signaling pathway: GLI1
hsa04210__85	0.960060320344037	DOWN	-0.0507546163446442	0.981476246967598	Apoptosis: FASLG*
hsa04062__59	0.961138905322758	DOWN	-0.049401159908787	0.982044591137282	Chemokine signaling pathway: FOXO3
hsa05210__53	0.96437507915983	DOWN	-0.0453407906012155	0.984815637902891	Colorectal cancer: CCND1*
hsa05205__144	0.965453936833344	DOWN	-0.0439873341653583	0.985381829065645	Proteoglycans in cancer: NUDT16L1
hsa05216__5	0.968690881422794	UP	0.0399269648577868	0.98764108013844	Thyroid cancer: MAPK1
hsa05110__14	0.969769980231731	DOWN	-0.0385735084219296	0.98764108013844	Vibrio cholerae infection: C00238*
hsa05110__15	0.969769980231731	DOWN	-0.0385735084219296	0.98764108013844	Vibrio cholerae infection: C01330
hsa05110__16	0.969769980231731	DOWN	-0.0385735084219296	0.98764108013844	Vibrio cholerae infection: C00698
hsa04390__80	0.970849134390827	UP	0.0372200519860724	0.988204508949276	Hippo signaling pathway: BIRC2
hsa05145__8	0.97624566633508	DOWN	-0.0304527698067865	0.993159505708509	Toxoplasmosis: NFKB1
hsa04150__31	0.979484123318196	UP	0.026392400499215	0.995914863482084	mTOR signaling pathway: EIF4E
hsa04933__56	0.982722918462397	UP	0.0223320311916435	0.998667584527228	AGE-RAGE signaling pathway in diabetic complications: NFATC1
hsa04110__43 83 84 85	0.98812151688606	DOWN	-0.0155647490123576	1	Cell cycle: SMC1B SMC3 STAG1 RAD21
hsa04932__138	0.990281122402442	DOWN	-0.0128578361406432	1	Non-alcoholic fatty liver disease (NAFLD): CEBPA
hsa04540__21	0.991360952853367	UP	0.011504379704786	1	Gap junction: C03758
hsa04912__14	0.991360952853367	DOWN	-0.011504379704786	1	GnRH signaling pathway: ATF4
hsa04917__68	0.994600531243025	DOWN	-0.00744401039721449	1	Prolactin signaling pathway: CCND1
hsa04014__45	0.99568041312528	UP	0.00609055396135731	1	Ras signaling pathway: RAB5A
hsa04015__27	0.996760302920264	UP	0.00473709752550013	1	Rap1 signaling pathway: RALA
hsa05131__12	0.997840198649834	DOWN	-0.00338364108964295	1	Shigellosis: ARPC5
hsa04152__33	1	0	0	1	AMPK signaling pathway: CPT1C
hsa04152__41	1	0	0	1	AMPK signaling pathway: FBP1
hsa04211__2	1	0	0	1	Longevity regulating pathway - mammal: RPS6KB1
hsa04911__41	1	0	0	1	Insulin secretion: ABCC8
hsa04911__35	1	0	0	1	Insulin secretion: TRPM4
hsa04922__67	1	0	0	1	Glucagon signaling pathway: FBP1
hsa04922__60	1	0	0	1	Glucagon signaling pathway: CPT1C*
hsa04924__34	1	0	0	1	Renin secretion: REN
hsa04924__47	1	0	0	1	Renin secretion: KCNMA1
hsa04931__151	1	0	0	1	Insulin resistance: CPT1A
hsa04931__29	1	0	0	1	Insulin resistance: CPT1B
hsa04960__15	1	0	0	1	Aldosterone-regulated sodium reabsorption: C00762
hsa05030__13	1	0	0	1	Cocaine addiction: SLC6A3
hsa05031__15	1	0	0	1	Amphetamine addiction: MAOA
hsa05031__77	1	0	0	1	Amphetamine addiction: MAOA*
hsa05034__7	1	0	0	1	Alcoholism: GRIN3A
hsa05034__75	1	0	0	1	Alcoholism: SLC29A1
hsa05140__37	1	0	0	1	Leishmaniasis: ELK1
hsa05140__55	1	0	0	1	Leishmaniasis: JUN
hsa05140__41 57	1	0	0	1	Leishmaniasis: NOS2 CYBA
hsa05145__10	1	DOWN	-0.00067672821792859	1	Toxoplasmosis: MAPK8
hsa05211__12	1	0	0	1	Renal cell carcinoma: EGLN2