p.value	UP.DOWN	statistic	FDRp.value	path.name
hsa04211__43 59 60 61	2.40530085320667e-68	UP	17.4705046140211	1.53856336247143e-65	Longevity regulating pathway - mammal: ULK3 RB1CC1 ATG13 ATG101
hsa04530__11 24 23	2.4099263870722e-68	DOWN	-17.4705046140211	1.53856336247143e-65	Tight junction: TJP1 YBX3 CDK4
hsa04750__8	2.45646092997035e-68	DOWN	-17.4693037888908	1.53856336247143e-65	Inflammatory mediator regulation of TRP channels: ASIC2
hsa03460__7	5.32417132807994e-66	UP	17.1597911115636	2.50102948136555e-63	Fanconi anemia pathway: FANCI
hsa04022__65	1.21924967911056e-64	DOWN	-16.9769654854799	4.58194029409748e-62	cGMP-PKG signaling pathway: PDE2A
hsa04919__28	3.76693036304677e-64	DOWN	-16.9106198970325	1.04253365453183e-61	Thyroid hormone signaling pathway: RCAN1
hsa04114__80	3.88384011800043e-64	UP	16.9088186593371	1.04253365453183e-61	Oocyte meiosis: CDC25C*
hsa04012__29	6.33068052235241e-64	DOWN	-16.8799988562106	1.48691858768752e-61	ErbB signaling pathway: STAT5A*
hsa04914__30	4.3874815890418e-63	UP	16.7653200562698	8.24426010314123e-61	Progesterone-mediated oocyte maturation: CDK1*
hsa05166__65	4.38757855409326e-63	UP	16.7653200562698	8.24426010314123e-61	HTLV-I infection: PTTG2
hsa04022__57	5.36951330616955e-63	DOWN	-16.7533118049671	9.17210500208417e-61	cGMP-PKG signaling pathway: C00144
hsa04152__78	6.37440086681664e-63	UP	16.7431047913598	9.54456969197694e-61	AMPK signaling pathway: CCNA2
hsa04270__10 3 71	6.60348089386377e-63	DOWN	-16.7410033473818	9.54456969197694e-61	Vascular smooth muscle contraction: ACTA2 MYL9 MYH11
hsa05166__64	7.75969828103759e-63	UP	16.7313967463397	1.04146236214783e-60	HTLV-I infection: CCNB2
hsa04925__18	1.47078411060513e-62	DOWN	-16.6932705484536	1.84240222921802e-60	Aldosterone synthesis and secretion: PDE2A
hsa04115__43 57	1.95876909803767e-62	UP	16.6761587903472	2.30032945950799e-60	p53 signaling pathway: CDK1 CCNB3
hsa04520__1 13	3.21962153830115e-62	DOWN	-16.646438368373	3.55862874733404e-60	Adherens junction: SMAD4 SMAD2
hsa05120__20	1.26173674967108e-61	UP	16.5644820532321	1.31711297368443e-59	Epithelial cell signaling in Helicobacter pylori infection: CXCL8
hsa05200__168	2.10866693364371e-61	UP	16.5335608061276	1.99098585110447e-59	Pathways in cancer: E2F1
hsa03320__38	2.1191972869659e-61	DOWN	-16.533260599845	1.99098585110447e-59	PPAR signaling pathway: SORBS1
hsa05034__99	4.14832301666303e-61	DOWN	-16.4927327516984	3.6876853965514e-59	Alcoholism: PDYN
hsa04115__11 12	4.42511734150381e-61	UP	16.488830070025	3.6876853965514e-59	p53 signaling pathway: CDK2 CCNE1
hsa04630__31	4.51393103356478e-61	UP	16.4876292448948	3.6876853965514e-59	Jak-STAT signaling pathway: BCL2L1
hsa04261__37	4.96066050233478e-61	DOWN	-16.481925325526	3.7843744356024e-59	Adrenergic signaling in cardiomyocytes: CREB3
hsa05205__422	5.03509105322299e-61	DOWN	-16.4810247066783	3.7843744356024e-59	Proteoglycans in cancer: CD63
hsa04921__76	6.951936937664e-61	DOWN	-16.4615112983114	5.02411134841179e-59	Oxytocin signaling pathway: CDKN1A
hsa04066__50	1.43279181219028e-60	DOWN	-16.4176811810565	9.97116968557609e-59	HIF-1 signaling pathway: TF
hsa04931__124	1.66194466624171e-60	DOWN	-16.4086749925795	1.10924587980209e-58	Insulin resistance: FOXO1*
hsa04211__56	1.71198140043963e-60	DOWN	-16.4068737548841	1.10924587980209e-58	Longevity regulating pathway - mammal: CAT
hsa03320__31	2.24658596499655e-60	DOWN	-16.3903624093429	1.40711167607617e-58	PPAR signaling pathway: CD36
hsa03320__36	2.79162644540611e-60	DOWN	-16.3771533329099	1.69208583578003e-58	PPAR signaling pathway: SLC27A4
hsa04110__59 15 16 17 18 19 20	2.88973532079275e-60	UP	16.3750518889319	1.69681645867799e-58	Cell cycle: CDC45 MCM7 MCM6 MCM5 MCM4 MCM3 MCM2
hsa05205__415	3.94256570248447e-60	DOWN	-16.3561388931302	2.24487301665707e-58	Proteoglycans in cancer: MAPK1******
hsa04630__24	4.48141795650704e-60	UP	16.3483335297834	2.47664245302257e-58	Jak-STAT signaling pathway: MCL1
hsa04910__17	4.99426872828309e-60	DOWN	-16.3417289915669	2.68120884012683e-58	Insulin signaling pathway: C00031
hsa05164__36	8.53762045553532e-60	DOWN	-16.3090065067671	4.45616356554191e-58	Influenza A: IL33
hsa04919__104	9.23591349811368e-60	DOWN	-16.304203206246	4.69034634133935e-58	Thyroid hormone signaling pathway: MYC
hsa03320__28	1.02898773608407e-59	DOWN	-16.2975986680295	5.08807356868941e-58	PPAR signaling pathway: ACSL1
hsa05205__284	1.11308800232692e-59	DOWN	-16.2927953675084	5.25446393321227e-58	Proteoglycans in cancer: PRKCA*
hsa04921__55	1.11856603155131e-59	DOWN	-16.2924951612258	5.25446393321227e-58	Oxytocin signaling pathway: PTGS2*
hsa04920__6	1.21591099227432e-59	DOWN	-16.2873916544222	5.49341085628463e-58	Adipocytokine signaling pathway: PTPN11
hsa04920__43	1.22790450220306e-59	DOWN	-16.286791241857	5.49341085628463e-58	Adipocytokine signaling pathway: C00162
hsa04152__87	1.30878719019948e-59	DOWN	-16.2828885601837	5.71909565205773e-58	AMPK signaling pathway: CD36
hsa03460__16 49	1.60816520210545e-59	UP	16.2702798963158	6.86759639717306e-58	Fanconi anemia pathway: FANCM C19orf40
hsa05321__152	1.78252519575823e-59	UP	16.2639755643819	7.26738036086009e-58	Inflammatory bowel disease (IBD): FOXP3*
hsa05205__337	1.79128239922151e-59	DOWN	-16.2636753580993	7.26738036086009e-58	Proteoglycans in cancer: CTNNB1**
hsa04920__2	1.81781201149773e-59	DOWN	-16.2627747392516	7.26738036086009e-58	Adipocytokine signaling pathway: C00638
hsa05200__227	4.13565029916229e-59	DOWN	-16.2123400837803	1.60040553545648e-57	Pathways in cancer: FOXO1
hsa04919__88	4.19670762896056e-59	DOWN	-16.2114394649326	1.60040553545648e-57	Thyroid hormone signaling pathway: FOXO1
hsa04114__59	4.25866294693049e-59	UP	16.2105388460849	1.60040553545648e-57	Oocyte meiosis: REC8*
hsa03320__30	4.97897580204324e-59	DOWN	-16.2009322450427	1.83441088863515e-57	PPAR signaling pathway: LPL
hsa04261__39	5.43622612090114e-59	DOWN	-16.1955285319565	1.96435940022562e-57	Adrenergic signaling in cardiomyocytes: SCN1B
hsa03320__40	5.93529591306832e-59	DOWN	-16.1901248188703	2.10423038125573e-57	PPAR signaling pathway: FABP4
hsa04068__52	6.11159438269725e-59	DOWN	-16.1883235811749	2.12660848983113e-57	FoxO signaling pathway: CAT
hsa03460__48	1.07036697952015e-58	UP	16.1537998586796	3.59146349021138e-57	Fanconi anemia pathway: RAD51
hsa04916__6	1.07036697952015e-58	DOWN	-16.1537998586796	3.59146349021138e-57	Melanogenesis: DCT
hsa04919__100	1.2386193240052e-58	DOWN	-16.1447936702026	4.08309773650135e-57	Thyroid hormone signaling pathway: CTNNB1*
hsa04261__36	1.27530678322016e-58	DOWN	-16.1429924325072	4.13155421667358e-57	Adrenergic signaling in cardiomyocytes: MAPK1
hsa03320__7	1.39199188125543e-58	DOWN	-16.137588719421	4.43314024555754e-57	PPAR signaling pathway: AQP7
hsa04931__61	1.67441825024353e-58	DOWN	-16.1261808806834	5.243719820346e-57	Insulin resistance: ACACB
hsa04390__96	2.11408841889969e-58	DOWN	-16.1117709791201	6.51208547395494e-57	Hippo signaling pathway: FGF1
hsa04970__18	2.64288891551366e-58	DOWN	-16.097961490122	7.9208530784567e-57	Salivary secretion: VAMP2
hsa04919__21 53	2.65574105344743e-58	DOWN	-16.0976612838395	7.9208530784567e-57	Thyroid hormone signaling pathway: THRA C02465
hsa05020__49	3.05679614360626e-58	UP	16.088955301645	8.97456242786901e-57	Prion diseases: BAX
hsa04920__16	3.30333153580354e-58	DOWN	-16.0841520011239	9.54916916273053e-57	Adipocytokine signaling pathway: POMC
hsa04540__14 31	3.85739035852174e-58	DOWN	-16.0745454000818	1.09818734600945e-56	Gap junction: GJA1 TJP1
hsa04923__16	4.68181475361291e-58	DOWN	-16.0625371487791	1.29997293283999e-56	Regulation of lipolysis in adipocytes: PLIN1
hsa04020__42	4.70453216780836e-58	DOWN	-16.0622369424965	1.29997293283999e-56	Calcium signaling pathway: MYLK4
hsa04923__66	6.47405706754084e-58	DOWN	-16.042423327847	1.7630077144796e-56	Regulation of lipolysis in adipocytes: LIPE
hsa04213__60	6.63245258397358e-58	DOWN	-16.0409222964342	1.78033977218377e-56	Longevity regulating pathway - multiple species: CAT
hsa04921__33	7.5935152737655e-58	DOWN	-16.0325165205223	2.00960777456414e-56	Oxytocin signaling pathway: C00942
hsa05205__304	1.65905888859624e-57	DOWN	-15.9838831027463	4.32968284954491e-56	Proteoglycans in cancer: MAPK1*****
hsa04630__28	2.34631437821357e-57	UP	15.9622682504015	6.03934892693603e-56	Jak-STAT signaling pathway: CCND1
hsa04115__38	2.52185441188995e-57	UP	15.957765156163	6.40346545938001e-56	p53 signaling pathway: GTSE1
hsa04066__48	2.65884219237881e-57	DOWN	-15.9544628870547	6.66128597263972e-56	HIF-1 signaling pathway: PFKFB3
hsa04930__3	3.28500161820451e-57	DOWN	-15.9412538106218	8.02836374318947e-56	Type II diabetes mellitus: SLC2A4
hsa05205__270	3.30082159599719e-57	DOWN	-15.9409536043392	8.02836374318947e-56	Proteoglycans in cancer: MAPK1****
hsa04270__24	3.33268957939744e-57	DOWN	-15.940353191774	8.02836374318947e-56	Vascular smooth muscle contraction: ACTA2
hsa04152__54	4.31918515021402e-57	DOWN	-15.9241420525154	1.02730998699394e-55	AMPK signaling pathway: SLC2A4*
hsa04931__149	4.59720556554485e-57	DOWN	-15.920239370842	1.07976865720735e-55	Insulin resistance: ACACB*
hsa04922__17	5.4375272782465e-57	DOWN	-15.9097321509522	1.26137206862039e-55	Glucagon signaling pathway: PKM
hsa04916__10	7.17983525134077e-57	DOWN	-15.8923201865632	1.64523298015479e-55	Melanogenesis: CAMK2A
hsa04914__11	1.02314511299178e-56	UP	15.8701049216532	2.31625261121875e-55	Progesterone-mediated oocyte maturation: CDK1
hsa04921__54	1.20953062600355e-56	DOWN	-15.8595977017634	2.70560481697698e-55	Oxytocin signaling pathway: RCAN1
hsa04152__44	1.32449867309061e-56	DOWN	-15.8538937823946	2.92792118439676e-55	AMPK signaling pathway: SLC2A4
hsa04550__34	1.54324891236215e-56	DOWN	-15.8442871813524	3.37181942596335e-55	Signaling pathways regulating pluripotency of stem cells: MAPK1*
hsa05215__25	2.28225364057716e-56	DOWN	-15.8196702661819	4.92914320763735e-55	Prostate cancer: FOXO1
hsa04970__32	2.43977509786974e-56	DOWN	-15.8154673782259	5.20947432829232e-55	Salivary secretion: RYR3
hsa04921__46	2.70946536790417e-56	DOWN	-15.8088628400094	5.68377850436671e-55	Oxytocin signaling pathway: C00942*
hsa04919__26	2.72240588287921e-56	DOWN	-15.8085626337269	5.68377850436671e-55	Thyroid hormone signaling pathway: THRB
hsa04540__14 16	3.20099404914087e-56	DOWN	-15.7983556201196	6.53768241123446e-55	Gap junction: GJA1 GJA1
hsa04540__14 15	3.20099404914087e-56	DOWN	-15.7983556201196	6.53768241123446e-55	Gap junction: GJA1 GJA1*
hsa04921__53	3.40537230941918e-56	DOWN	-15.7944529384462	6.88031674128886e-55	Oxytocin signaling pathway: RGS2
hsa04913__35	4.17856870859237e-56	DOWN	-15.7815440682958	8.35269213132453e-55	Ovarian steroidogenesis: HSD17B2
hsa04932__35	5.71849313167342e-56	DOWN	-15.7617304536463	1.13105774678046e-54	Non-alcoholic fatty liver disease (NAFLD): PRKAG2
hsa04152__64	8.89175954973688e-56	DOWN	-15.7338112693675	1.74037668687038e-54	AMPK signaling pathway: ACACB
hsa04921__23	1.10059536052618e-55	DOWN	-15.720301986652	2.13197802312237e-54	Oxytocin signaling pathway: C00219
hsa05214__35	1.18165343950425e-55	UP	15.7157988924135	2.26563960492702e-54	Glioma: E2F1
hsa04261__52	1.42806210397565e-55	DOWN	-15.7037906411108	2.7104330236063e-54	Adrenergic signaling in cardiomyocytes: MAPK14
hsa03320__10	1.50437748929675e-55	DOWN	-15.7004883720025	2.82672530238859e-54	PPAR signaling pathway: PLIN1
hsa04630__27	1.52588673651292e-55	UP	15.6995877531548	2.83875364149284e-54	Jak-STAT signaling pathway: PIM1
hsa04110__43 83 84 85	2.03615479641935e-55	DOWN	-15.6812751699182	3.75091653183526e-54	Cell cycle: SMC1B SMC3 STAG1 RAD21
hsa03320__59	2.09472209716601e-55	DOWN	-15.6794739322228	3.82134254424751e-54	PPAR signaling pathway: NR1H3
hsa04960__3	2.20648718827604e-55	DOWN	-15.6761716631146	3.98652829497182e-54	Aldosterone-regulated sodium reabsorption: SCNN1A
hsa05212__34	3.69100079553377e-55	UP	15.6434491783147	6.605133804579e-54	Pancreatic cancer: E2F1
hsa04921__58	3.76127477595087e-55	DOWN	-15.6422483531844	6.66739179623743e-54	Oxytocin signaling pathway: MEF2C
hsa04722__53	3.81485332075077e-55	DOWN	-15.6413477343367	6.69916765391654e-54	Neurotrophin signaling pathway: JUN
hsa04960__4	4.27176409223322e-55	DOWN	-15.6341427835551	7.40676616874728e-54	Aldosterone-regulated sodium reabsorption: ATP1B4
hsa05020__24	4.41488989302659e-55	DOWN	-15.6320413395771	7.40676616874728e-54	Prion diseases: PRNP*
hsa05020__26	4.41488989302659e-55	DOWN	-15.6320413395771	7.40676616874728e-54	Prion diseases: PRNP**
hsa05020__25 8	4.41488989302659e-55	DOWN	-15.6320413395771	7.40676616874728e-54	Prion diseases: PRNP PRNP*
hsa05020__10 34	4.41488989302659e-55	DOWN	-15.6320413395771	7.40676616874728e-54	Prion diseases: PRNP PRNP***
hsa04012__56	6.71276511556059e-55	DOWN	-15.6053229804286	1.11621996921578e-53	ErbB signaling pathway: JUN
hsa05205__431	7.06920421078348e-55	DOWN	-15.6020207113204	1.16517848351423e-53	Proteoglycans in cancer: CDKN1A*
hsa04010__13	1.02953257540581e-54	UP	15.578004208715	1.68216670364133e-53	MAPK signaling pathway: STMN1
hsa04910__48	1.09432880727707e-54	DOWN	-15.5741015270416	1.77262399040829e-53	Insulin signaling pathway: PPARGC1A
hsa04620__20	1.43659008321088e-54	UP	15.5566895626527	2.30713911654124e-53	Toll-like receptor signaling pathway: IFNB1*
hsa04921__28	1.70068206916322e-54	UP	15.5458821364802	2.70812000674381e-53	Oxytocin signaling pathway: EEF2
hsa04068__51	1.87651680768675e-54	DOWN	-15.5395778045463	2.93831256803617e-53	FoxO signaling pathway: BCL6
hsa04068__56	1.87651680768675e-54	DOWN	-15.5395778045463	2.93831256803617e-53	FoxO signaling pathway: BCL6*
hsa04110__10 11 12 13 14 9 15 16 17 18 19 20	2.41628929279967e-54	UP	15.5233666652877	3.7522376703889e-53	Cell cycle: ORC3 ORC5 ORC4 ORC2 ORC1 ORC6 MCM7 MCM6 MCM5 MCM4 MCM3 MCM2
hsa04210__74	3.22902468920437e-54	UP	15.5047538757685	4.97322736968443e-53	Apoptosis: BAX*
hsa04066__58	3.68036122120417e-54	DOWN	-15.4963480998566	5.6222753940184e-53	HIF-1 signaling pathway: EDN1
hsa04012__48	3.7673285292326e-54	DOWN	-15.4948470684437	5.70871798905489e-53	ErbB signaling pathway: CAMK2A
hsa03460__25 40	4.23383684933494e-54	UP	15.4873419113796	6.36430355192028e-53	Fanconi anemia pathway: MLH1 PMS2
hsa04931__87	4.60493476426963e-54	DOWN	-15.4819381982933	6.86720033497035e-53	Insulin resistance: C00031*
hsa03320__53	4.82491751846896e-54	DOWN	-15.4789361354677	7.13859843874266e-53	PPAR signaling pathway: ADIPOQ
hsa03320__47	7.7261323266916e-54	DOWN	-15.4486153009283	1.13417208139481e-52	PPAR signaling pathway: PLTP
hsa04270__48	8.55949043968221e-54	DOWN	-15.4420107627118	1.24676608807464e-52	Vascular smooth muscle contraction: KCNMB2*
hsa04066__56	9.17842789332556e-54	DOWN	-15.4375076684733	1.32663584704298e-52	HIF-1 signaling pathway: TEK
hsa04630__30	1.11588317939376e-53	UP	15.4248990046055	1.60056831609228e-52	Jak-STAT signaling pathway: CDKN1A
hsa04713__61	1.19648096171274e-53	DOWN	-15.420395910367	1.70317252049867e-52	Circadian entrainment: FOS
hsa04012__57	1.4408819866307e-53	DOWN	-15.4083876590643	2.0356520698339e-52	ErbB signaling pathway: ABL1
hsa04722__50	1.83431779200855e-53	UP	15.3927769323708	2.57215159043586e-52	Neurotrophin signaling pathway: RHOA
hsa04916__9	1.9303678195674e-53	DOWN	-15.3894746632625	2.6867860244201e-52	Melanogenesis: PRKACA
hsa04012__35	2.21854087433265e-53	DOWN	-15.3804684747855	3.06517522269931e-52	ErbB signaling pathway: CBLC
hsa04066__44	2.49113219509606e-53	DOWN	-15.3729633177213	3.4166696310843e-52	HIF-1 signaling pathway: GAPDH
hsa04713__60	3.3351752748245e-53	DOWN	-15.3540503219195	4.54115531985163e-52	Circadian entrainment: PER1
hsa04390__5	3.41325966670891e-53	DOWN	-15.3525492905067	4.61403950629212e-52	Hippo signaling pathway: SAV1
hsa04921__48	4.03185923148885e-53	DOWN	-15.3417418643343	5.41133106854825e-52	Oxytocin signaling pathway: PRKAG2
hsa04960__27	4.58914515278604e-53	DOWN	-15.3333360884224	6.1156054908404e-52	Aldosterone-regulated sodium reabsorption: KCNJ1
hsa04261__73	5.27157623287199e-53	DOWN	-15.3243298999453	6.97555756448342e-52	Adrenergic signaling in cardiomyocytes: KCNE1
hsa04022__3	5.57203900158052e-53	DOWN	-15.3207274245545	7.2707370027568e-52	cGMP-PKG signaling pathway: MYL9
hsa04024__9 95	5.57203900158052e-53	DOWN	-15.3207274245545	7.2707370027568e-52	cAMP signaling pathway: ATP1B4 FXYD1
hsa04261__72	8.28662654536531e-53	DOWN	-15.2949096842537	1.07383250198217e-51	Adrenergic signaling in cardiomyocytes: ATP2B1
hsa04920__28	1.29551353445576e-52	DOWN	-15.2657896748447	1.66730817208382e-51	Adipocytokine signaling pathway: SLC2A1
hsa04066__45	1.58617158327844e-52	DOWN	-15.2525805984117	2.02749415304774e-51	HIF-1 signaling pathway: ALDOA
hsa04068__59	1.854503060728e-52	DOWN	-15.2423735848044	2.35446706155939e-51	FoxO signaling pathway: S1PR1
hsa03320__33	2.0051614797834e-52	DOWN	-15.2372700780007	2.52865665806242e-51	PPAR signaling pathway: CYP7A1
hsa05210__21	2.32258487324364e-52	UP	15.2276634769586	2.90942465121653e-51	Colorectal cancer: BIRC5
hsa04068__45	3.10102304752449e-52	DOWN	-15.2087504811568	3.85105332813308e-51	FoxO signaling pathway: RBL2
hsa05211__48	3.11527464542964e-52	DOWN	-15.2084502748743	3.85105332813308e-51	Renal cell carcinoma: JUN
hsa03320__20	3.43009076830318e-52	DOWN	-15.2021459429403	4.21251016577888e-51	PPAR signaling pathway: SCP2
hsa04550__36	3.60743776937441e-52	DOWN	-15.1988436738321	4.40154257704838e-51	Signaling pathways regulating pluripotency of stem cells: AKT3*
hsa04921__67	6.16270552609722e-52	DOWN	-15.1637195387717	7.47078947324947e-51	Oxytocin signaling pathway: RYR1
hsa03320__25	6.84586074970336e-52	DOWN	-15.1568147942726	8.24575150557218e-51	PPAR signaling pathway: EHHADH
hsa04742__34	6.94035612334342e-52	UP	15.1559141754249	8.3063243030333e-51	Taste transduction: GRM1
hsa04915__12 14	8.96299185508368e-52	DOWN	-15.1391026236011	1.06591529719634e-50	Estrogen signaling pathway: ESR1 FOS
hsa05110__12	1.28509421326486e-51	UP	15.1153863272783	1.50918251670292e-50	Vibrio cholerae infection: C00080
hsa05120__35	1.28509421326486e-51	UP	15.1153863272783	1.50918251670292e-50	Epithelial cell signaling in Helicobacter pylori infection: C00080
hsa04915__3 11	1.38228596448902e-51	DOWN	-15.1105830267572	1.60328106621905e-50	Estrogen signaling pathway: ESR1 C00951
hsa04915__12 13	1.38228596448902e-51	DOWN	-15.1105830267572	1.60328106621905e-50	Estrogen signaling pathway: ESR1 C00951*
hsa03460__16 34	2.8361788475685e-51	UP	15.0631504341115	3.2694356163075e-50	Fanconi anemia pathway: FANCM STRA13
hsa04270__65	4.65035163860275e-51	DOWN	-15.0304279493117	5.32805532252107e-50	Vascular smooth muscle contraction: NPR2
hsa04610__11	4.69285348037975e-51	UP	15.0298275367465	5.34416466038397e-50	Complement and coagulation cascades: F2R
hsa05211__43	5.52414032958232e-51	DOWN	-15.0190201105741	6.25292751764167e-50	Renal cell carcinoma: RAP1A
hsa04921__11	7.51471596540702e-51	DOWN	-14.9986060833595	8.45518041856276e-50	Oxytocin signaling pathway: PRKACA
hsa04110__60 10 11 12 13 14 9	7.75640020261131e-51	DOWN	-14.9965046393815	8.67516427423015e-50	Cell cycle: CDC6 ORC3 ORC5 ORC4 ORC2 ORC1 ORC6
hsa05012__71	8.04209979661834e-51	DOWN	-14.994102989121	8.94148255493838e-50	Parkinson's disease: PRKACA*
hsa05160__7	9.04497336813662e-51	UP	14.9862976257742	9.99735585807571e-50	Hepatitis C: IRF3
hsa05120__50	1.25200293317913e-50	DOWN	-14.9646827734294	1.37573889558104e-49	Epithelial cell signaling in Helicobacter pylori infection: EGFR
hsa03320__23	1.84498914496202e-50	DOWN	-14.9388650331286	2.01554337406026e-49	PPAR signaling pathway: ACADL
hsa04810__35 81 80	2.0741741498919e-50	DOWN	-14.9310596697818	2.25281689459357e-49	Regulation of actin cytoskeleton: MYL12B MYH9 ACTB
hsa04722__37	2.35276637676318e-50	UP	14.9226538938699	2.54071725398737e-49	Neurotrophin signaling pathway: NFKB1
hsa05133__73	2.66858991831632e-50	DOWN	-14.914248117958	2.86530311800936e-49	Pertussis: FOS
hsa04340__14	6.78720252082983e-50	DOWN	-14.851805211184	7.24610996399957e-49	Hedgehog signaling pathway: PTCH1
hsa05217__10	7.83270520984859e-50	DOWN	-14.8421986101418	8.31505824254548e-49	Basal cell carcinoma: PTCH1*
hsa05162__13	1.00624206952743e-49	UP	14.825387058318	1.06220721833823e-48	Measles: IRF7
hsa04068__60	1.11519023811235e-49	DOWN	-14.818482313819	1.17063824436487e-48	FoxO signaling pathway: RAG1
hsa04932__31 133	1.50410540801973e-49	DOWN	-14.7983684928869	1.57011892314948e-48	Non-alcoholic fatty liver disease (NAFLD): PPARA RXRA
hsa05217__4	1.5176259527604e-49	DOWN	-14.7977680803218	1.57548020178828e-48	Basal cell carcinoma: PTCH1
hsa04066__88	1.60109874700617e-49	DOWN	-14.794165604931	1.65300249759593e-48	HIF-1 signaling pathway: BCL2
hsa05012__70	1.62267140917606e-49	DOWN	-14.7932649860833	1.6661199878917e-48	Parkinson's disease: PRKACA
hsa04066__52	1.63721368811233e-49	DOWN	-14.7926645735181	1.67191549997993e-48	HIF-1 signaling pathway: FLT1
hsa04910__18	1.9921000916584e-49	DOWN	-14.7794554970852	2.02332760660872e-48	Insulin signaling pathway: LIPE
hsa04072__3	2.38070454235366e-49	DOWN	-14.7674472457825	2.40502356724867e-48	Phospholipase D signaling pathway: MAPK1
hsa04066__46	3.04103156286358e-49	DOWN	-14.7509359002412	3.05566754364742e-48	HIF-1 signaling pathway: ENO1
hsa05020__52	3.2220539356037e-49	DOWN	-14.7470332185679	3.22034007712731e-48	Prion diseases: FYN
hsa04960__13	4.26319845224838e-49	DOWN	-14.7281202227661	4.23838618612418e-48	Aldosterone-regulated sodium reabsorption: FXYD4
hsa03460__28	4.30123747918697e-49	UP	14.727519810201	4.25369748599595e-48	Fanconi anemia pathway: RAD51C
hsa05200__189	4.65915602637245e-49	UP	14.7221160971148	4.58353621652033e-48	Pathways in cancer: BIRC5
hsa04390__76	4.97995943127027e-49	DOWN	-14.7176130028762	4.87361654758168e-48	Hippo signaling pathway: MYC
hsa04066__29	5.1599494497546e-49	DOWN	-14.7152113526157	5.01993133982699e-48	HIF-1 signaling pathway: LDHA
hsa04020__8	5.18289877555314e-49	DOWN	-14.7149111463331	5.01993133982699e-48	Calcium signaling pathway: PDE1A
hsa04921__57	8.70553588619593e-49	DOWN	-14.6797870112727	8.38856509239084e-48	Oxytocin signaling pathway: FOS
hsa05211__40	8.9003796366583e-49	UP	14.6782859798599	8.53255782514334e-48	Renal cell carcinoma: PAK4
hsa03320__22	1.22927122026829e-48	DOWN	-14.6563709212325	1.1724876258295e-47	PPAR signaling pathway: ACADM
hsa04931__13	1.3019671739756e-48	DOWN	-14.6524682395591	1.23555369691927e-47	Insulin resistance: AKT2
hsa04726__64	2.18209980062117e-48	UP	14.6173441044987	2.06038468611416e-47	Serotonergic synapse: CASP3
hsa04915__66	2.63734094982596e-48	DOWN	-14.6044352343483	2.47778182236149e-47	Estrogen signaling pathway: AKT3*
hsa03320__60	2.74398036014076e-48	DOWN	-14.6017333778052	2.56514382920621e-47	PPAR signaling pathway: CYP27A1
hsa04012__47	2.94426674614937e-48	DOWN	-14.5969300772841	2.73875109703696e-47	ErbB signaling pathway: PRKCA
hsa04924__49	3.18702820019622e-48	DOWN	-14.5915263641979	2.9499635409698e-47	Renin secretion: PDE1A
hsa04211__23	4.83925526056253e-48	DOWN	-14.5630067673539	4.4573336444103e-47	Longevity regulating pathway - mammal: SOD2
hsa04622__45	6.13379388114094e-48	UP	14.5467956280953	5.6221457086165e-47	RIG-I-like receptor signaling pathway: MAPK14
hsa04620__21	9.54948732500525e-48	UP	14.516474793556	8.71043042897324e-47	Toll-like receptor signaling pathway: IFNA1
hsa04668__40	1.28024636823229e-47	DOWN	-14.4963609726239	1.16211735551134e-46	TNF signaling pathway: JUN
hsa05134__73	1.84783587358482e-47	DOWN	-14.4711436448882	1.66927096464706e-46	Legionellosis: CXCL1
hsa04210__84	2.36946697629761e-47	DOWN	-14.4540318867819	2.13025284615465e-46	Apoptosis: FAS**
hsa04530__11 13	2.49671340377396e-47	DOWN	-14.4504294113911	2.23396404080537e-46	Tight junction: TJP1 EPB41
hsa04261__34	4.87998874877857e-47	DOWN	-14.4041976438757	4.34573405637675e-46	Adrenergic signaling in cardiomyocytes: AKT3
hsa04068__55	5.05257842867414e-47	DOWN	-14.4017959936151	4.45718068895714e-46	FoxO signaling pathway: ATM
hsa04530__5 15	5.05257842867414e-47	DOWN	-14.4017959936151	4.45718068895714e-46	Tight junction: IGSF5 MPDZ
hsa03320__21	6.08978419878888e-47	DOWN	-14.3888871234647	5.3470581820207e-46	PPAR signaling pathway: ACAA1
hsa04623__9	6.38754524619405e-47	UP	14.3855848543565	5.58241745004587e-46	Cytosolic DNA-sensing pathway: IKBKE
hsa05030__73	7.21249131327274e-47	DOWN	-14.3771790784446	6.27419961927754e-46	Cocaine addiction: NFKB1
hsa04211__52	8.65276697387734e-47	DOWN	-14.3645704145768	7.49241896032973e-46	Longevity regulating pathway - mammal: PPARG
hsa04922__78	9.6843055506643e-47	DOWN	-14.35676505123	8.34716060995331e-46	Glucagon signaling pathway: ACACA
hsa04740__21	1.2501633586274e-46	DOWN	-14.3390528805585	1.07262874468534e-45	Olfactory transduction: PDE1A
hsa04390__58	1.26649079829547e-46	DOWN	-14.3381522617108	1.08169827727145e-45	Hippo signaling pathway: SMAD7
hsa04933__52	1.58571230385416e-46	DOWN	-14.3225415350173	1.34821421671582e-45	AGE-RAGE signaling pathway in diabetic complications: FOXO1
hsa04728__44	1.60639831998282e-46	DOWN	-14.3216409161696	1.35964974921069e-45	Dopaminergic synapse: FOS
hsa05031__98	1.7437910856605e-46	DOWN	-14.3159369968008	1.46931993271573e-45	Amphetamine addiction: FOS
hsa04726__10	1.98491274047105e-46	DOWN	-14.3069308083238	1.66502278542192e-45	Serotonergic synapse: PRKACA
hsa04710__7	2.07244310732075e-46	DOWN	-14.3039287454981	1.73072026606919e-45	Circadian rhythm: PER1
hsa04211__38	2.93861542404839e-46	UP	14.2796120366101	2.44321167335705e-45	Longevity regulating pathway - mammal: BAX
hsa03320__44	3.05476709392984e-46	DOWN	-14.276910180067	2.52859355484325e-45	PPAR signaling pathway: FABP1
hsa04022__66	3.1482563165428e-46	UP	14.274808736089	2.59454983279996e-45	cGMP-PKG signaling pathway: PDE3A
hsa05110__50	3.23056625018936e-46	DOWN	-14.2730074983936	2.65075719829948e-45	Vibrio cholerae infection: ACTB
hsa05211__31	3.4759470252558e-46	DOWN	-14.26790399159	2.83969759150246e-45	Renal cell carcinoma: SOS1
hsa05020__62	3.55155802723325e-46	DOWN	-14.2664029601771	2.88890802301787e-45	Prion diseases: NOTCH1
hsa05205__129	3.67595439260273e-46	DOWN	-14.2640013099166	2.96442845652383e-45	Proteoglycans in cancer: AKT3*
hsa05211__46	3.67595439260273e-46	DOWN	-14.2640013099166	2.96442845652383e-45	Renal cell carcinoma: AKT3
hsa04919__101	3.82108971160759e-46	DOWN	-14.2612994533735	3.06830237953447e-45	Thyroid hormone signaling pathway: NOTCH1
hsa04916__15	3.9379031865288e-46	DOWN	-14.2591980093955	3.14864684573941e-45	Melanogenesis: MITF*
hsa04213__52	4.51881913768224e-46	DOWN	-14.2495914083534	3.5978225252987e-45	Longevity regulating pathway - multiple species: SOD2
hsa04540__21	4.71727915948088e-46	DOWN	-14.2465893455277	3.73998630407788e-45	Gap junction: C03758
hsa04115__29	4.94561986931965e-46	DOWN	-14.2432870764194	3.90454610691245e-45	p53 signaling pathway: IGF1
hsa04066__89	5.52999874134948e-46	DOWN	-14.2354817130727	4.34764336192288e-45	HIF-1 signaling pathway: CDKN1A
hsa04910__43	5.57769858741947e-46	DOWN	-14.2348813005076	4.36687318573382e-45	Insulin signaling pathway: G6PC
hsa04152__81	7.24678670472998e-46	DOWN	-14.2165687172709	5.65008805733927e-45	AMPK signaling pathway: LIPE
hsa04962__10	7.46762759440676e-46	DOWN	-14.214467273293	5.79821167350839e-45	Vasopressin-regulated water reabsorption: AQP2
hsa04910__42	8.75108125355543e-46	DOWN	-14.203359640838	6.76678258248175e-45	Insulin signaling pathway: PCK1
hsa04620__48	1.14609228087494e-45	UP	14.1844466450362	8.82584998263943e-45	Toll-like receptor signaling pathway: CD80
hsa04726__45	1.29188204085112e-45	DOWN	-14.1760408691243	9.90794430513978e-45	Serotonergic synapse: TRPC1
hsa04014__24	1.34262438661485e-45	DOWN	-14.1733390125812	1.02552488717452e-44	Ras signaling pathway: PLD1
hsa04390__79	1.74244018645307e-45	DOWN	-14.1550264293446	1.32552433617219e-44	Hippo signaling pathway: SNAI2
hsa05205__434	1.92222172746841e-45	DOWN	-14.1481216848455	1.45639299431982e-44	Proteoglycans in cancer: CASP3
hsa04152__60	2.61318135833207e-45	UP	14.1265068325007	1.97195492863693e-44	AMPK signaling pathway: EEF2
hsa04921__41	2.62434203202974e-45	DOWN	-14.1262066262181	1.97245547127355e-44	Oxytocin signaling pathway: PTGS2
hsa04068__58	2.93176915201016e-45	DOWN	-14.1184012628713	2.19473873969207e-44	FoxO signaling pathway: KLF2
hsa04919__49	3.72093197231878e-45	DOWN	-14.1015897110475	2.77445681586785e-44	Thyroid hormone signaling pathway: ACTB
hsa05034__84	3.96616830098644e-45	DOWN	-14.097086616809	2.94562459982353e-44	Alcoholism: FOSB
hsa04066__55	5.47819248935173e-45	DOWN	-14.0742709393339	4.05256838090232e-44	HIF-1 signaling pathway: ANGPT1
hsa04722__46	5.7645314107347e-45	DOWN	-14.0706684639431	4.24766843951784e-44	Neurotrophin signaling pathway: ATF4*
hsa05200__219	6.04006915929378e-45	DOWN	-14.0673661948348	4.43331638684102e-44	Pathways in cancer: MYC**
hsa04152__27	6.91839531040126e-45	DOWN	-14.0577595937927	5.05823532616497e-44	AMPK signaling pathway: ADIPOR1
hsa04340__32	7.37277138116608e-45	DOWN	-14.0532564995542	5.36954938961669e-44	Hedgehog signaling pathway: PTCH1***
hsa04068__53	7.8568307491748e-45	DOWN	-14.0487534053156	5.69999419988395e-44	FoxO signaling pathway: SOD2
hsa04152__35	1.25170385676118e-44	DOWN	-14.0157307142332	9.04596748790101e-44	AMPK signaling pathway: PFKFB1
hsa04530__11 36 14	1.30025581440782e-44	DOWN	-14.0130288576901	9.36084549912754e-44	Tight junction: TJP1 CTNNB1 CTNNA1
hsa04024__113	1.8385048460384e-44	DOWN	-13.9884119425196	1.3185307655367e-43	cAMP signaling pathway: PTCH1
hsa04662__27	2.61998250382226e-44	DOWN	-13.9631946147839	1.87184301318708e-43	B cell receptor signaling pathway: NFATC1
hsa05219__10	3.56257444623354e-44	DOWN	-13.9412795561564	2.53563537290637e-43	Bladder cancer: EGFR
hsa05205__140	3.63829433910407e-44	DOWN	-13.9397785247436	2.57975662761379e-43	Proteoglycans in cancer: MAPK1***
hsa04919__31	3.73127453529299e-44	DOWN	-13.9379772870482	2.63573866609606e-43	Thyroid hormone signaling pathway: ATP2A2
hsa04014__67	5.22213644748404e-44	DOWN	-13.9139607844428	3.67505407671255e-43	Ras signaling pathway: RAPGEF5*
hsa04261__20	5.44602419704558e-44	DOWN	-13.9109587216171	3.81831323367487e-43	Adrenergic signaling in cardiomyocytes: ATP1B4
hsa04917__31	6.49544210006574e-44	DOWN	-13.8983500577493	4.53715082008309e-43	Prolactin signaling pathway: GALT
hsa04810__82 83	7.58525762805474e-44	UP	13.8872424252943	5.27877743819069e-43	Regulation of actin cytoskeleton: ACTB ARPC5
hsa04022__19	9.43084497461987e-44	DOWN	-13.8716316986008	6.5389511835095e-43	cGMP-PKG signaling pathway: CNGB1
hsa04550__66	1.00418517903817e-43	DOWN	-13.8671286043623	6.9369998213703e-43	Signaling pathways regulating pluripotency of stem cells: MYC
hsa04390__95	1.10099155081204e-43	DOWN	-13.8605240661458	7.57788690101033e-43	Hippo signaling pathway: AFP
hsa04915__21	1.16250242833063e-43	DOWN	-13.8566213844724	7.97205132420893e-43	Estrogen signaling pathway: CREB3
hsa04921__56	1.26387439077913e-43	DOWN	-13.850617258821	8.63570901917812e-43	Oxytocin signaling pathway: JUN
hsa05110__51	1.80238609027186e-43	UP	13.8250997248028	1.22705922594957e-42	Vibrio cholerae infection: PDIA4
hsa04919__40	2.1384495570202e-43	DOWN	-13.8127912672175	1.45059448290287e-42	Thyroid hormone signaling pathway: RCAN2
hsa04933__23	2.14738144928777e-43	DOWN	-13.8124910609349	1.45141357669487e-42	AGE-RAGE signaling pathway in diabetic complications: F3
hsa04933__43	3.04667311439822e-43	UP	13.7872737331993	2.05186336270762e-42	AGE-RAGE signaling pathway in diabetic complications: CASP3
hsa04152__94	4.39219838283446e-43	DOWN	-13.7608555803333	2.94747884333784e-42	AMPK signaling pathway: MLYCD
hsa04213__62	5.22869512525361e-43	DOWN	-13.7482469164655	3.49634097521407e-42	Longevity regulating pathway - multiple species: CAT*
hsa04670__18	5.70448736117941e-43	DOWN	-13.7419425845316	3.80096870626103e-42	Leukocyte transendothelial migration: CDH5
hsa03320__63	6.51382115821875e-43	DOWN	-13.7323359834894	4.32490104462651e-42	PPAR signaling pathway: DBI
hsa04913__12	7.71958014843191e-43	DOWN	-13.7200275259041	5.1074264432759e-42	Ovarian steroidogenesis: HSD3B1
hsa05161__100	7.84848918109152e-43	UP	13.7188267007739	5.17449514781437e-42	Hepatitis B: MMP9*
hsa04620__18	8.63237260089425e-43	UP	13.7119219562748	5.67140843254556e-42	Toll-like receptor signaling pathway: CXCL11
hsa04211__42	9.61262937561344e-43	DOWN	-13.704116592928	6.29342529504448e-42	Longevity regulating pathway - mammal: PPARGC1A
hsa05152__97	9.77296461578184e-43	UP	13.7029157677978	6.37618073369934e-42	Tuberculosis: IL18
hsa05169__31	1.07035513297106e-42	DOWN	-13.6963112295813	6.95916018980144e-42	Epstein-Barr virus infection: MYC
hsa04015__63	1.10177426795293e-42	DOWN	-13.6942097856033	7.13873741201225e-42	Rap1 signaling pathway: GNAI1
hsa05110__46	1.61749506874482e-42	DOWN	-13.6662906013245	1.04442379181152e-41	Vibrio cholerae infection: PLCG1
hsa04261__23	1.74931818050588e-42	DOWN	-13.6605866819557	1.12567426752416e-41	Adrenergic signaling in cardiomyocytes: SLC9A1
hsa05166__60	1.80797023323635e-42	UP	13.6581850316952	1.15944575708229e-41	HTLV-I infection: POLD3
hsa04310__22	2.17622756376143e-42	DOWN	-13.6446757489797	1.39086108581896e-41	Wnt signaling pathway: ROCK2
hsa04211__50	2.96298351362543e-42	DOWN	-13.6221602777871	1.88726983800074e-41	Longevity regulating pathway - mammal: PPARGC1A*
hsa05205__30	3.49234622643877e-42	DOWN	-13.6101520264844	2.21693194576975e-41	Proteoglycans in cancer: FLNA
hsa04932__28	4.63569949024009e-42	UP	13.5894377929872	2.93282132732698e-41	Non-alcoholic fatty liver disease (NAFLD): GSK3A
hsa03320__41	5.03190243588432e-42	DOWN	-13.5834336673359	3.17280022719014e-41	PPAR signaling pathway: ANGPTL4
hsa04066__42	5.05257361671326e-42	DOWN	-13.5831334610533	3.17517920595459e-41	HIF-1 signaling pathway: HK1
hsa05160__56	6.17598764595902e-42	DOWN	-13.5684233532075	3.868226928919e-41	Hepatitis C: MAPK1
hsa05152__98	7.99236542683224e-42	UP	13.5495103574057	4.98925403223182e-41	Tuberculosis: IL23A
hsa04919__29	8.22444847402065e-42	DOWN	-13.5474089134278	5.11713201413404e-41	Thyroid hormone signaling pathway: HIF1A
hsa04620__19	9.68516564762723e-42	UP	13.5354006621251	6.00608127125134e-41	Toll-like receptor signaling pathway: CXCL10
hsa04210__75	1.16387916944551e-41	UP	13.5218913794095	7.19384526114511e-41	Apoptosis: BAK1*
hsa03320__55	1.46253244182872e-41	DOWN	-13.5050798275857	9.01015887933171e-41	PPAR signaling pathway: SCD
hsa04115__31	1.81499948897699e-41	DOWN	-13.4891688946097	1.11450458816594e-40	p53 signaling pathway: ADGRB1
hsa04068__67	2.22453612938986e-41	DOWN	-13.4741585804813	1.36153204792298e-40	FoxO signaling pathway: GABARAP
hsa04923__38	2.52333910502456e-41	DOWN	-13.4648521857217	1.53940070725362e-40	Regulation of lipolysis in adipocytes: PDE3B
hsa03320__9	2.68192990489769e-41	DOWN	-13.4603490914832	1.63085640495235e-40	PPAR signaling pathway: PCK1
hsa05164__90	3.25910486458442e-41	DOWN	-13.4459391899199	1.97543807759811e-40	Influenza A: MAPK1
hsa05231__50	4.05717177087739e-41	DOWN	-13.4297280506613	2.45126230144007e-40	Choline metabolism in cancer: WASF2
hsa04961__5	4.77104171892415e-41	DOWN	-13.4177197993586	2.87332929162131e-40	Endocrine and other factor-regulated calcium reabsorption: TRPV5
hsa04810__48	5.58705975610078e-41	DOWN	-13.4060117543384	3.35402085677743e-40	Regulation of actin cytoskeleton: IQGAP2
hsa03320__58	7.06398644939618e-41	DOWN	-13.3885997899495	4.22714348357179e-40	PPAR signaling pathway: CYP8B1
hsa05152__94	7.44498877843677e-41	UP	13.3846971082761	4.44099489355006e-40	Tuberculosis: CAMP
hsa05231__34	8.57539565122332e-41	DOWN	-13.3741898883863	5.09910393311665e-40	Choline metabolism in cancer: PLD1
hsa04022__39	9.25891849303985e-41	DOWN	-13.3684859690175	5.48817282284602e-40	cGMP-PKG signaling pathway: KCNJ8
hsa04390__17 51	1.0366145767622e-40	DOWN	-13.3600801931056	6.12515342684332e-40	Hippo signaling pathway: YWHAQ YAP1
hsa04152__61	1.05347193486911e-40	UP	13.3588793679753	6.20524691416635e-40	AMPK signaling pathway: RPS6KB1
hsa05160__71	1.16988876368427e-40	DOWN	-13.3510740046286	6.86944058425856e-40	Hepatitis C: MAPK8
hsa04066__64	1.88867652546679e-40	DOWN	-13.315349457003	1.10555239605984e-39	HIF-1 signaling pathway: LTBR
hsa04360__40 142	2.1478295213813e-40	UP	13.3057428559609	1.2533452393402e-39	Axon guidance: UNC5D PTPN11
hsa04350__10	2.26294670133962e-40	DOWN	-13.3018401742875	1.31643246186289e-39	TGF-beta signaling pathway: SMAD4
hsa04971__55	2.3368164699742e-40	DOWN	-13.2994385240269	1.35520930465479e-39	Gastric acid secretion: MYLK4
hsa03460__27	2.5628180954161e-40	UP	13.2925337795279	1.48170313885749e-39	Fanconi anemia pathway: BRCA1
hsa04750__40	3.04522477833265e-40	DOWN	-13.2796249093775	1.75520777867701e-39	Inflammatory mediator regulation of TRP channels: C00219
hsa04390__94	3.23393195716773e-40	DOWN	-13.275121815139	1.85827466284959e-39	Hippo signaling pathway: GLI2
hsa05132__13	3.43426372731595e-40	DOWN	-13.2706187209004	1.9673724218374e-39	Salmonella infection: FOS
hsa04261__4	4.19546020233703e-40	DOWN	-13.2556084067721	2.3961306140399e-39	Adrenergic signaling in cardiomyocytes: SLC8A1
hsa05030__77	4.24612982966347e-40	DOWN	-13.2547077879244	2.4177205908902e-39	Cocaine addiction: BDNF
hsa04068__96	4.50875181755e-40	DOWN	-13.2502046936858	2.55949989884485e-39	FoxO signaling pathway: CCNG2
hsa04670__15	5.4407273043749e-40	DOWN	-13.2360949984052	3.07925500148206e-39	Leukocyte transendothelial migration: PECAM1
hsa05200__205	5.68527004296016e-40	UP	13.2327927292969	3.20799471793457e-39	Pathways in cancer: SLC2A1
hsa04210__83	5.82318147236302e-40	DOWN	-13.2309914916015	3.27597544508087e-39	Apoptosis: TP53*
hsa04068__50	6.03631002663084e-40	DOWN	-13.2282896350584	3.38573926568339e-39	FoxO signaling pathway: TNFSF10
hsa05161__188	6.13350666941247e-40	UP	13.2270888099281	3.43001756899584e-39	Hepatitis B: IFNB1
hsa04064__133	6.96923099143417e-40	DOWN	-13.217482208886	3.88581158246433e-39	NF-kappa B signaling pathway: CXCL2
hsa04530__5 10	8.33931874265916e-40	DOWN	-13.2039729261704	4.63597038978005e-39	Tight junction: IGSF5 MAGI1
hsa05010__59	8.74780545900908e-40	DOWN	-13.2003704507796	4.84870986946256e-39	Alzheimer's disease: LRP1
hsa04072__27	9.17633780849713e-40	DOWN	-13.1967679753888	5.07127610063709e-39	Phospholipase D signaling pathway: C01245
hsa04924__52	9.51131729862989e-40	DOWN	-13.1940661188457	5.24098686337993e-39	Renin secretion: KCNJ2
hsa04728__70 73	1.16989347245058e-39	DOWN	-13.1784553921522	6.42757261618317e-39	Dopaminergic synapse: KIF5A GRIA1
hsa04152__24	1.48509017430159e-39	DOWN	-13.1604430151981	8.1355231414364e-39	AMPK signaling pathway: SIRT1
hsa04610__58	1.71336334652065e-39	UP	13.1496355890257	9.35874920962881e-39	Complement and coagulation cascades: F2RL2
hsa04068__88	1.81127563691224e-39	DOWN	-13.1454327010698	9.86488962828437e-39	FoxO signaling pathway: FBXO32
hsa04530__20 37	1.89961539165275e-39	UP	13.1418302256789	1.03161194246113e-38	Tight junction: ACTB TJP3
hsa04916__8	2.72467816670443e-39	DOWN	-13.1145114539653	1.47540930122122e-38	Melanogenesis: TYR*
hsa04390__60	2.85724999038117e-39	DOWN	-13.1109089785745	1.53393506626463e-38	Hippo signaling pathway: CTGF*
hsa05214__23	2.85724999038117e-39	DOWN	-13.1109089785745	1.53393506626463e-38	Glioma: MAPK1
hsa05214__56	2.85724999038117e-39	DOWN	-13.1109089785745	1.53393506626463e-38	Glioma: MAPK1*
hsa04360__82	3.08039024452225e-39	DOWN	-13.1052050592057	1.64901802548641e-38	Axon guidance: ILK
hsa05211__45	3.93617672172672e-39	DOWN	-13.0865922696865	2.10115797162628e-38	Renal cell carcinoma: ETS1
hsa04622__5 33	4.1600182560362e-39	UP	13.0823893817306	2.21435532665496e-38	RIG-I-like receptor signaling pathway: MAVS TMEM173
hsa04530__5 11 31	4.57357434278243e-39	DOWN	-13.0751844309489	2.42761191810401e-38	Tight junction: IGSF5 TJP1 MLLT4
hsa05212__29	4.72031444262116e-39	DOWN	-13.0727827806884	2.49844248948878e-38	Pancreatic cancer: VEGFA
hsa05218__21	5.35558320022724e-39	UP	13.0631761796462	2.81880695608599e-38	Melanoma: RB1
hsa05220__40	5.35558320022724e-39	UP	13.0631761796462	2.81880695608599e-38	Chronic myeloid leukemia: RB1
hsa04520__4	6.02808235229865e-39	UP	13.0541699911692	3.16390132401373e-38	Adherens junction: CTNND1
hsa04022__50	6.57400474745236e-39	DOWN	-13.0475654529527	3.440823097622e-38	cGMP-PKG signaling pathway: ATP2B1
hsa04921__43	6.67841797487921e-39	DOWN	-13.0463646278225	3.48576315966612e-38	Oxytocin signaling pathway: CACNG3
hsa05210__39	6.78447984320391e-39	UP	13.0451638026922	3.53131236160115e-38	Colorectal cancer: BAD
hsa04728__74	7.34043871840534e-39	DOWN	-13.0391596770408	3.81013379886288e-38	Dopaminergic synapse: GRIN2A
hsa04071__65	8.65969934593228e-39	UP	13.026551013173	4.48252756777046e-38	Sphingolipid signaling pathway: BAX*
hsa05215__39	9.22209988660841e-39	UP	13.0217477126519	4.76052903487286e-38	Prostate cancer: RB1
hsa05212__27	9.74389916488769e-39	DOWN	-13.017544824696	5.01610589885588e-38	Pancreatic cancer: BCL2L1*
hsa05014__49	1.05406315731214e-38	DOWN	-13.0115406990446	5.41143353166532e-38	Amyotrophic lateral sclerosis (ALS): C00001
hsa04972__42	1.09629572984911e-38	DOWN	-13.0085386362189	5.61291464955444e-38	Pancreatic secretion: CFTR
hsa03320__26	1.3184471052372e-38	DOWN	-12.9944289409383	6.73196225744754e-38	PPAR signaling pathway: CPT2
hsa04068__66	2.22874685604765e-38	DOWN	-12.9542012990742	1.13490930691424e-37	FoxO signaling pathway: BNIP3
hsa05223__28	2.28167228006735e-38	UP	12.9524000613788	1.15871951736393e-37	Non-small cell lung cancer: RB1
hsa04151__26	2.4195156955856e-38	DOWN	-12.9478969671403	1.22540970134915e-37	PI3K-Akt signaling pathway: RBL2
hsa05034__61	2.45765176370778e-38	DOWN	-12.94669614201	1.24137840430293e-37	Alcoholism: CRH
hsa04730__7	2.91870480409114e-38	DOWN	-12.933487065577	1.47030732624323e-37	Long-term depression: GNA13
hsa04972__39	3.85053658703503e-38	DOWN	-12.9121724195147	1.93453429065209e-37	Pancreatic secretion: KCNMA1*
hsa05216__11	4.22816754022979e-38	DOWN	-12.9049674687331	2.11859381549114e-37	Thyroid cancer: MYC
hsa04530__11 43	4.43056639622092e-38	DOWN	-12.9013649933423	2.2141048559838e-37	Tight junction: TJP1 ACTN4
hsa03320__57	5.97901383411666e-38	DOWN	-12.8782491095846	2.97999124517379e-37	PPAR signaling pathway: APOC3
hsa04668__120	6.09641044738927e-38	UP	12.8767480781718	3.03046434673133e-37	TNF signaling pathway: DNM1L
hsa04068__72	7.75723447275016e-38	DOWN	-12.8581352886526	3.84586901696505e-37	FoxO signaling pathway: SMAD2
hsa04976__16	7.78741496801033e-38	DOWN	-12.85783508237	3.85067176970826e-37	Bile secretion: CFTR
hsa04919__43	1.06213360046819e-37	DOWN	-12.8338185797646	5.23818644430375e-37	Thyroid hormone signaling pathway: TBC1D4
hsa04024__101	1.13445965254646e-37	UP	12.8287150729609	5.58023478307541e-37	cAMP signaling pathway: HCN4
hsa05205__324	1.2941217389227e-37	DOWN	-12.8185080593536	6.34896800897065e-37	Proteoglycans in cancer: KDR*
hsa04152__63	1.57032879545763e-37	DOWN	-12.8034977452253	7.68397866318981e-37	AMPK signaling pathway: PPARG
hsa05164__24	1.65766776467037e-37	UP	12.7992948572693	8.09027981770294e-37	Influenza A: IRF7
hsa04962__22	1.70313110668591e-37	DOWN	-12.7971934132913	8.29063043902285e-37	Vasopressin-regulated water reabsorption: ARHGDIA
hsa05205__144	2.15558537945234e-37	UP	12.7788808300547	1.04660075658681e-36	Proteoglycans in cancer: NUDT16L1
hsa05140__62	2.79112841691718e-37	DOWN	-12.7587670091227	1.35168306582149e-36	Leishmaniasis: C00584
hsa04390__12	4.89442681886603e-37	DOWN	-12.7149368918678	2.36417172047539e-36	Hippo signaling pathway: CTGF
hsa04920__40	5.59825991775535e-37	DOWN	-12.704429671978	2.69721291934931e-36	Adipocytokine signaling pathway: PPARGC1A
hsa04068__68	6.28102402891312e-37	DOWN	-12.6954234835009	3.01842561389456e-36	FoxO signaling pathway: ATG12
hsa04520__44 49	6.37810202706557e-37	DOWN	-12.6942226583707	3.05725859919801e-36	Adherens junction: ACTB VCL
hsa05014__13	6.42719878577086e-37	UP	12.6936222458055	3.07295331258612e-36	Amyotrophic lateral sclerosis (ALS): CASP3
hsa05200__199	7.43476588988884e-37	DOWN	-12.682214407068	3.53668990053193e-36	Pathways in cancer: BCL2L1**
hsa05220__3	7.43476588988884e-37	DOWN	-12.682214407068	3.53668990053193e-36	Chronic myeloid leukemia: BCL2L1
hsa05168__122	9.07241320627063e-37	UP	12.6666036803744	4.30481424610669e-36	Herpes simplex infection: CASP3
hsa04931__77	9.79125371797508e-37	UP	12.6605995547231	4.63419791840685e-36	Insulin resistance: PPP2R4**
hsa04728__36	9.9446556520848e-37	UP	12.6593987295928	4.69497687695159e-36	Dopaminergic synapse: TH
hsa04630__1	1.05316260083176e-36	UP	12.6548956353543	4.95963039339067e-36	Jak-STAT signaling pathway: MYC
hsa04213__71	1.13247826860743e-36	DOWN	-12.6491917159855	5.3198166667834e-36	Longevity regulating pathway - multiple species: SIRT1**
hsa05166__120	1.63984447679641e-36	UP	12.6200717065765	7.68395953092382e-36	HTLV-I infection: E2F1
hsa04530__8	2.06094550921687e-36	UP	12.6020593296224	9.633125900046e-36	Tight junction: LLGL2
hsa04630__7	2.19034848064722e-36	UP	12.5972560291013	1.02125677298663e-35	Jak-STAT signaling pathway: BCL2
hsa04664__30	2.47386930372731e-36	DOWN	-12.5876494280592	1.15059416378802e-35	Fc epsilon RI signaling pathway: PRKCA
hsa05200__224	2.67945703929611e-36	DOWN	-12.5813450961253	1.24007383665946e-35	Pathways in cancer: MYC***
hsa05221__12	2.67945703929611e-36	DOWN	-12.5813450961253	1.24007383665946e-35	Acute myeloid leukemia: MYC
hsa04976__95 96	2.71844287969065e-36	UP	12.580144270995	1.25502559482524e-35	Bile secretion: SLC51A SLC51B
hsa05205__318	2.76216693612072e-36	DOWN	-12.5789434458647	1.2720861943556e-35	Proteoglycans in cancer: HSPB2
hsa04550__62 63	2.92414611253976e-36	DOWN	-12.5744403516262	1.34339133140885e-35	Signaling pathways regulating pluripotency of stem cells: SMAD2 SMAD4
hsa05161__213	3.21534957951798e-36	UP	12.566935194562	1.47357118534495e-35	Hepatitis B: E2F1
hsa04068__13	3.56228241019584e-36	DOWN	-12.5588296249327	1.62859577828662e-35	FoxO signaling pathway: PCK1
hsa05200__192	3.94639122477996e-36	DOWN	-12.5507240553034	1.79982259984503e-35	Pathways in cancer: PTGS2
hsa04932__58	5.61259471290502e-36	UP	12.5228048710246	2.55352674710618e-35	Non-alcoholic fatty liver disease (NAFLD): BAX
hsa04062__60	6.35858084011183e-36	UP	12.5128980636998	2.88593560351936e-35	Chemokine signaling pathway: GSK3A
hsa03320__42	9.81512435787941e-36	DOWN	-12.4783743412046	4.44400449842299e-35	PPAR signaling pathway: ACOX1
hsa04920__9	1.15849750713244e-35	UP	12.4651652647716	5.2327327305333e-35	Adipocytokine signaling pathway: G6PC
hsa05120__53	1.45743012320776e-35	DOWN	-12.446852681535	6.56717314510165e-35	Epithelial cell signaling in Helicobacter pylori infection: GIT1
hsa05010__12	1.57123934550847e-35	UP	12.4408485558836	7.0630591631828e-35	Alzheimer's disease: CASP3
hsa05166__62 63	1.75212015636966e-35	UP	12.4321425736892	7.85735984204913e-35	HTLV-I infection: ANAPC10 CDC20
hsa04740__42	2.32164323964134e-35	DOWN	-12.4096271024966	1.03865896363954e-34	Olfactory transduction: PDE2A
hsa05014__5	2.40131189893608e-35	UP	12.4069252459535	1.07174941997646e-34	Amyotrophic lateral sclerosis (ALS): TOMM40
hsa04722__84	2.53067284493772e-35	DOWN	-12.4027223579975	1.12680907005639e-34	Neurotrophin signaling pathway: NFKB1*
hsa04152__15	3.0747392687661e-35	DOWN	-12.387111631304	1.36582389740225e-34	AMPK signaling pathway: FOXO1
hsa04066__47	3.10945485732969e-35	DOWN	-12.3862110124563	1.37798718795342e-34	HIF-1 signaling pathway: PGK1
hsa04622__11	3.65203199959984e-35	UP	12.3733021423059	1.61462779464661e-34	RIG-I-like receptor signaling pathway: IRF7
hsa05213__31	4.40215617094711e-35	DOWN	-12.3582918281775	1.94170221718536e-34	Endometrial cancer: MYC
hsa04012__40	5.13003353402442e-35	DOWN	-12.3459833705923	2.25745503757187e-34	ErbB signaling pathway: ELK1*
hsa04922__59	6.53644065652418e-35	DOWN	-12.3264699622254	2.86961962467498e-34	Glucagon signaling pathway: CPT1C
hsa04724__67	7.04180497238559e-35	DOWN	-12.320465836574	3.08427774897728e-34	Glutamatergic synapse: PLD1
hsa04210__102	7.58596974305297e-35	DOWN	-12.3144617109227	3.31489235981315e-34	Apoptosis: PIDD1
hsa04390__14	8.23290232203538e-35	DOWN	-12.3078571727062	3.58923978262285e-34	Hippo signaling pathway: AREG
hsa04622__21 22 23	9.13609967340752e-35	UP	12.2994513967943	3.9737803903548e-34	RIG-I-like receptor signaling pathway: CHUK IKBKB IKBKG
hsa04931__46	9.20425825239773e-35	DOWN	-12.2988509842291	3.99418042869638e-34	Insulin resistance: PIK3R5*
hsa04213__53	9.23852674727734e-35	DOWN	-12.2985507779466	3.99981376915533e-34	Longevity regulating pathway - multiple species: SOD1
hsa04724__66	1.02512500989212e-34	DOWN	-12.2901450020347	4.42806872089034e-34	Glutamatergic synapse: PLA2G4B
hsa05168__123	1.13320556904465e-34	UP	12.2820394324054	4.88370014732776e-34	Herpes simplex infection: CYCS
hsa05034__62	1.17604630187651e-34	DOWN	-12.2790373695797	5.05672997992209e-34	Alcoholism: NPY
hsa05205__91	1.24334230048933e-34	UP	12.2745342753412	5.33388169547819e-34	Proteoglycans in cancer: RAC1*
hsa05016__60	1.60562060872059e-34	UP	12.253820041844	6.85672982678634e-34	Huntington's disease: CASP3*
hsa05134__35	1.60562060872059e-34	UP	12.253820041844	6.85672982678634e-34	Legionellosis: CASP3
hsa05031__97	1.76130087861616e-34	DOWN	-12.2463148847798	7.50449966194959e-34	Amphetamine addiction: ARC
hsa04922__50	1.84808978866652e-34	DOWN	-12.2424122031064	7.85647220114116e-34	Glucagon signaling pathway: PCK1
hsa05169__104	2.27317850163538e-34	UP	12.2256006512827	9.64176615027737e-34	Epstein-Barr virus infection: IRF3
hsa05012__57	2.33272623806382e-34	UP	12.2234992073047	9.8720554083827e-34	Parkinson's disease: CASP3
hsa05169__45	2.48387231479484e-34	DOWN	-12.218395700501	1.0488081077527e-33	Epstein-Barr virus infection: RB1
hsa05162__23	2.53015070757474e-34	UP	12.2168946690882	1.06595362769797e-33	Measles: IRF3
hsa05030__76	2.62529264183568e-34	DOWN	-12.2138926062625	1.10109930223421e-33	Cocaine addiction: PDYN
hsa05205__121	2.62529264183568e-34	UP	12.2138926062625	1.10109930223421e-33	Proteoglycans in cancer: PLAUR
hsa05100__55	2.66433705424812e-34	DOWN	-12.2126917811322	1.11498648662188e-33	Bacterial invasion of epithelial cells: ACTB*
hsa05205__215 216	3.9234400576144e-34	DOWN	-12.1811701214626	1.6382541929461e-33	Proteoglycans in cancer: EIF4B RPS6
hsa04722__70	4.1767578883719e-34	UP	12.176066614659	1.74016143508887e-33	Neurotrophin signaling pathway: ZNF274
hsa04066__30	4.28572816131259e-34	DOWN	-12.173965170681	1.78161133077574e-33	HIF-1 signaling pathway: PDK1
hsa04068__46	6.88355790157864e-34	DOWN	-12.1352385602298	2.85523295740977e-33	FoxO signaling pathway: PLK4
hsa05215__43	9.09351778263427e-34	DOWN	-12.1124228827547	3.7635946946189e-33	Prostate cancer: C05981
hsa04726__38	1.0604417244071e-33	DOWN	-12.0998142188868	4.37927472562846e-33	Serotonergic synapse: PLA2G4B
hsa04340__26	1.1284438251814e-33	DOWN	-12.0947107120832	4.64988146385055e-33	Hedgehog signaling pathway: PTCH1**
hsa04066__60	1.14925648710352e-33	DOWN	-12.0932096806703	4.72527995463352e-33	HIF-1 signaling pathway: NOS3
hsa04068__43	1.25458799005897e-33	DOWN	-12.0860047298887	5.14709788934675e-33	FoxO signaling pathway: CDKN1A
hsa04933__19	1.25917902241467e-33	DOWN	-12.0857045236062	5.15467839459078e-33	AGE-RAGE signaling pathway in diabetic complications: TGFBR2
hsa04066__43	1.30601715550128e-33	DOWN	-12.0827024607805	5.33479616344979e-33	HIF-1 signaling pathway: PFKL
hsa04914__29	1.55604469215944e-33	UP	12.0682925592172	6.34231665199041e-33	Progesterone-mediated oocyte maturation: CDK2
hsa04610__57	1.66770786720475e-33	UP	12.0625886398484	6.78273394475698e-33	Complement and coagulation cascades: PLAUR
hsa05130__9	2.20760792836876e-33	DOWN	-12.0394727560907	8.95916910886587e-33	Pathogenic Escherichia coli infection: TLR4
hsa04068__44	2.22373259020428e-33	DOWN	-12.0388723435256	9.00515848490051e-33	FoxO signaling pathway: CDKN1B
hsa04010__54	2.56261571569266e-33	DOWN	-12.0271642985055	1.0355171892014e-32	MAPK signaling pathway: NR4A1
hsa04022__45	2.7759180177205e-33	DOWN	-12.020559760289	1.11930256551434e-32	cGMP-PKG signaling pathway: CREB3
hsa04210__62	3.03977836327396e-33	DOWN	-12.0130546032248	1.22307142282479e-32	Apoptosis: TP53AIP1
hsa04976__34	3.11799026849311e-33	DOWN	-12.0109531592468	1.25185976805525e-32	Bile secretion: SLCO1B1
hsa04970__27	3.16363044309144e-33	DOWN	-12.0097523341166	1.26747582144325e-32	Salivary secretion: PRKCA
hsa05217__22	3.37719708423536e-33	DOWN	-12.0043486210303	1.35016028112303e-32	Basal cell carcinoma: LEF1
hsa05131__38	6.22746125675414e-33	UP	11.9536137592764	2.48437360964778e-32	Shigellosis: CXCL8
hsa05213__27	1.08520317848493e-32	UP	11.907381991761	4.32012028045164e-32	Endometrial cancer: ELK1
hsa05031__101	1.71904551461204e-32	DOWN	-11.8689555875924	6.82893556438907e-32	Amphetamine addiction: FOS*
hsa05166__114 112 113	1.7946664791344e-32	DOWN	-11.8653531122015	7.11430024112561e-32	HTLV-I infection: DLG1 CTNNB1 APC2
hsa04724__44	1.87358986706167e-32	DOWN	-11.8617506368107	7.41152707412395e-32	Glutamatergic synapse: PRKACA*
hsa05211__42	2.24126142549714e-32	UP	11.8467403226824	8.84733239182591e-32	Renal cell carcinoma: SLC2A1*
hsa04933__22	2.48646540196157e-32	DOWN	-11.8380343404879	9.79469285175216e-32	AGE-RAGE signaling pathway in diabetic complications: EDN1
hsa05134__71	3.71035793148637e-32	UP	11.8044112368403	1.45852773080813e-31	Legionellosis: CXCL8
hsa04390__18	3.9283424864305e-32	UP	11.7996079363192	1.54099280417597e-31	Hippo signaling pathway: MOB1A
hsa04550__69	3.99903572245284e-32	DOWN	-11.7981069049064	1.56545585885185e-31	Signaling pathways regulating pluripotency of stem cells: ID1
hsa04931__35	4.38751389100568e-32	DOWN	-11.7903015415596	1.71395812914754e-31	Insulin resistance: C00369
hsa05160__54	4.67818777145241e-32	UP	11.7848978284734	1.82371676816578e-31	Hepatitis C: IRF1
hsa04152__77	4.81343874122363e-32	UP	11.7824961782129	1.87255722458782e-31	AMPK signaling pathway: CCND1
hsa04022__43	5.41361762632154e-32	DOWN	-11.7725893708882	2.10169163633433e-31	cGMP-PKG signaling pathway: MAPK1
hsa03320__66	5.47173130747095e-32	DOWN	-11.7716887520405	2.11987280963668e-31	PPAR signaling pathway: UCP1
hsa05200__216	7.42862885311313e-32	DOWN	-11.7458710117396	2.872097451646e-31	Pathways in cancer: IL6
hsa04360__6	7.77957072640974e-32	UP	11.7419683300663	3.00160439320819e-31	Axon guidance: MAPK1
hsa05210__9 11	9.35573339285409e-32	DOWN	-11.7263576033727	3.60234078794525e-31	Colorectal cancer: SMAD2 SMAD4
hsa05152__51	1.01503958941038e-31	UP	11.7194528588737	3.90032594785707e-31	Tuberculosis: CASP3
hsa04913__19	1.11296480037953e-31	DOWN	-11.7116474955269	4.26787930594519e-31	Ovarian steroidogenesis: STAR
hsa03320__46	1.20737664318556e-31	DOWN	-11.7047427510279	4.62049024958383e-31	PPAR signaling pathway: APOA2
hsa05010__47	1.29133465148068e-31	DOWN	-11.6990388316591	4.93174351652884e-31	Alzheimer's disease: C00533
hsa04068__40	1.44603684687277e-31	DOWN	-11.6894322306169	5.51136558879094e-31	FoxO signaling pathway: CCND1
hsa04630__33	1.46145095704988e-31	DOWN	-11.6885316117692	5.55883876173427e-31	Jak-STAT signaling pathway: RAF1
hsa04540__1	1.61339937148424e-31	DOWN	-11.6801258358573	6.12439882630078e-31	Gap junction: C00681
hsa04072__36	1.61912401943135e-31	DOWN	-11.6798256295748	6.13373796877322e-31	Phospholipase D signaling pathway: MTOR
hsa04024__110	1.86466188937986e-31	DOWN	-11.6678173782721	7.04969756568362e-31	cAMP signaling pathway: FOS
hsa05200__190	1.97292544899965e-31	DOWN	-11.663014077751	7.44402995716937e-31	Pathways in cancer: MYC*
hsa04064__136	1.98688988038633e-31	UP	11.6624136651858	7.48169556161506e-31	NF-kappa B signaling pathway: TNFSF13B*
hsa04066__53	2.13204554207889e-31	DOWN	-11.6564095395345	8.01222714713247e-31	HIF-1 signaling pathway: EGF*
hsa04950__20	2.20852331001779e-31	UP	11.6534074767088	8.28306447010663e-31	Maturity onset diabetes of the young: NKX6-1
hsa05210__22	2.36974354204687e-31	DOWN	-11.6474033510575	8.87001616634674e-31	Colorectal cancer: MYC
hsa05161__207	3.01039092451411e-31	UP	11.6269893238429	1.12232629904008e-30	Hepatitis B: CDK2
hsa05161__219	3.01039092451411e-31	UP	11.6269893238429	1.12232629904008e-30	Hepatitis B: CDK2*
hsa05220__15	3.3334022077979e-31	DOWN	-11.6182833416484	1.24028965315886e-30	Chronic myeloid leukemia: MYC
hsa04666__41	3.47691950944638e-31	UP	11.6146808662576	1.29113275854738e-30	Fc gamma R-mediated phagocytosis: MARCKS
hsa04390__77	3.55096177612746e-31	DOWN	-11.6128796285622	1.31602705667525e-30	Hippo signaling pathway: CCND1
hsa05133__24	4.01514330407013e-31	DOWN	-11.6023724086723	1.48512879298185e-30	Pertussis: NFKB1
hsa04014__44	4.78453761521285e-31	DOWN	-11.587362094544	1.76277376058528e-30	Ras signaling pathway: ETS1
hsa04210__86	4.78453761521285e-31	DOWN	-11.587362094544	1.76277376058528e-30	Apoptosis: BCL2L11
hsa04014__26	4.97253098974827e-31	DOWN	-11.5840598254357	1.82845121912661e-30	Ras signaling pathway: PRKCA
hsa04620__77	7.43496917154363e-31	UP	11.5495361029404	2.72857560025986e-30	Toll-like receptor signaling pathway: CXCL9
hsa04921__65	8.16999127566887e-31	DOWN	-11.5414305333111	2.99247828596137e-30	Oxytocin signaling pathway: TRPM2
hsa04390__80	8.97709219261839e-31	DOWN	-11.5333249636818	3.28170354667898e-30	Hippo signaling pathway: BIRC2
hsa04261__66	9.26333608490735e-31	DOWN	-11.5306231071387	3.37976864146426e-30	Adrenergic signaling in cardiomyocytes: C01245
hsa04666__27	1.05017793419779e-30	UP	11.5198156809662	3.82419445418149e-30	Fc gamma R-mediated phagocytosis: ARPC5
hsa04925__3	1.4872191083668e-30	DOWN	-11.4897950527095	5.4051928522654e-30	Aldosterone synthesis and secretion: ITPR1
hsa05130__26	1.76309967824356e-30	DOWN	-11.4750849448637	6.39549091779855e-30	Pathogenic Escherichia coli infection: CTNNB1
hsa04750__44	1.82531308360069e-30	UP	11.472082882038	6.59569862324171e-30	Inflammatory mediator regulation of TRP channels: TRPA1
hsa04750__63	1.82531308360069e-30	UP	11.472082882038	6.59569862324171e-30	Inflammatory mediator regulation of TRP channels: TRPA1*
hsa03320__37	2.17092348412886e-30	DOWN	-11.4570725679096	7.82949179784671e-30	PPAR signaling pathway: HMGCS2
hsa03320__27	2.20122266596102e-30	DOWN	-11.4558717427793	7.9235582171279e-30	PPAR signaling pathway: CPT1C
hsa05168__79	2.65378559115144e-30	UP	11.4396606035207	9.53434632079072e-30	Herpes simplex infection: EIF2S1
hsa04024__76	2.87354102511742e-30	DOWN	-11.4327558590216	1.03041671492283e-29	cAMP signaling pathway: C00416
hsa05200__146 147	3.69775836644709e-30	DOWN	-11.4108408003942	1.31842276481102e-29	Pathways in cancer: RARB RXRA
hsa05222__14 15	3.69775836644709e-30	DOWN	-11.4108408003942	1.31842276481102e-29	Small cell lung cancer: RXRA RARB
hsa05223__29 34	3.69775836644709e-30	DOWN	-11.4108408003942	1.31842276481102e-29	Non-small cell lung cancer: RARB RXRA
hsa04115__58	3.82765323750731e-30	UP	11.4078387375685	1.36215159721141e-29	p53 signaling pathway: CASP3
hsa04722__35	4.42423596320745e-30	DOWN	-11.3952300737007	1.57148192341527e-29	Neurotrophin signaling pathway: FOXO3
hsa03320__65	5.42113280830098e-30	DOWN	-11.3775179030292	1.92194500882973e-29	PPAR signaling pathway: ME1
hsa04921__77	8.444543789928e-30	DOWN	-11.338791292578	2.98819167255644e-29	Oxytocin signaling pathway: KCNJ3
hsa04662__24	9.6195391686581e-30	DOWN	-11.3273834538404	3.39757783795274e-29	B cell receptor signaling pathway: FOS
hsa05030__69	1.02664966163952e-29	DOWN	-11.3216795344716	3.6192771373746e-29	Cocaine addiction: PRKACA**
hsa05223__7	1.79819507303336e-29	DOWN	-11.2724457041305	6.32735682065485e-29	Non-small cell lung cancer: FOXO3
hsa04014__103	1.99182330271451e-29	DOWN	-11.2634395156535	6.99558128187021e-29	Ras signaling pathway: KSR2
hsa05164__77	2.12501302608366e-29	UP	11.2577355962847	7.44943932091643e-29	Influenza A: CASP9
hsa04550__67	2.21364794740237e-29	DOWN	-11.2541331208939	7.74570669119004e-29	Signaling pathways regulating pluripotency of stem cells: MYC*
hsa04742__31	2.78977373973672e-29	DOWN	-11.2337190936793	9.74346627688717e-29	Taste transduction: C00076*
hsa04919__102	2.83758375451204e-29	DOWN	-11.2322180622665	9.89205913678687e-29	Thyroid hormone signaling pathway: BMP4
hsa04666__29	2.89602999616545e-29	UP	11.2304168245711	1.00771117829535e-28	Fc gamma R-mediated phagocytosis: WAS
hsa05231__48	2.95567054903295e-29	UP	11.2286155868757	1.02656283948852e-28	Choline metabolism in cancer: WAS
hsa05231__60	3.53831515900656e-29	DOWN	-11.2127046538996	1.22665944350061e-28	Choline metabolism in cancer: PRKCA
hsa05134__59	3.7866497332854e-29	UP	11.2067005282482	1.31033422630631e-28	Legionellosis: HSPA1A
hsa04022__60	4.60889989495321e-29	DOWN	-11.1892885638593	1.59193435709873e-28	cGMP-PKG signaling pathway: TRPC6*
hsa05200__204	4.76758265751411e-29	UP	11.1862865010336	1.64372253458147e-28	Pathways in cancer: TGFB1*
hsa05200__96	4.78374601319496e-29	DOWN	-11.1859862947511	1.6462744979475e-28	Pathways in cancer: C00416
hsa04970__21	6.29070849877903e-29	DOWN	-11.1616695858631	2.16092162142702e-28	Salivary secretion: ITPR1
hsa04115__64	7.44709394785473e-29	UP	11.1466592717347	2.55348349051442e-28	p53 signaling pathway: PMAIP1
hsa04666__49	8.81408035243077e-29	UP	11.1316489576063	3.01669526087749e-28	Fc gamma R-mediated phagocytosis: ARF6*
hsa04630__35	9.84984348560033e-29	DOWN	-11.1217421502816	3.36506471080782e-28	Jak-STAT signaling pathway: MTOR
hsa04530__4 53	1.61382960879455e-28	UP	11.0776118267442	5.50342256792187e-28	Tight junction: OCLN OCLN
hsa05010__61	1.72570575400757e-28	UP	11.0716077010928	5.87427737641345e-28	Alzheimer's disease: GAPDH
hsa03320__8	2.04019394887129e-28	DOWN	-11.0565973869644	6.93223224218654e-28	PPAR signaling pathway: GK
hsa04530__4 45	2.29354351210265e-28	UP	11.0460901670746	7.77900407805214e-28	Tight junction: OCLN TJP2
hsa05205__183	2.62147958205607e-28	UP	11.0340819157719	8.87524348591595e-28	Proteoglycans in cancer: VEGFA*
hsa04211__57	2.81185124606426e-28	DOWN	-11.027777583838	9.50264117150134e-28	Longevity regulating pathway - mammal: ATG5
hsa04540__10	3.08716743939647e-28	DOWN	-11.0193718079261	1.04143404284129e-27	Gap junction: C00533
hsa04270__17	3.88508914650148e-28	DOWN	-10.9986575744289	1.30825851366958e-27	Vascular smooth muscle contraction: ITPR1
hsa04068__14	4.19411343245493e-28	DOWN	-10.9917528299298	1.4097923326624e-27	FoxO signaling pathway: G6PC
hsa04668__141	4.29291577605115e-28	DOWN	-10.9896513859519	1.44042656128573e-27	TNF signaling pathway: JUN*
hsa04152__82	4.43807933684331e-28	UP	10.9866493231262	1.48647969232238e-27	AMPK signaling pathway: HMGCR
hsa04022__23	4.82263958890065e-28	UP	10.979144166062	1.61240921486554e-27	cGMP-PKG signaling pathway: CACNA1C
hsa04213__55	4.91974660334747e-28	DOWN	-10.9773429283666	1.64195450580638e-27	Longevity regulating pathway - multiple species: CRYAB
hsa04068__49	5.17108215692853e-28	DOWN	-10.9728398341281	1.72277719377105e-27	FoxO signaling pathway: BCL2L11
hsa04066__62	5.84681767401888e-28	DOWN	-10.9617322016731	1.94445493973124e-27	HIF-1 signaling pathway: NPPA
hsa04022__49	6.24782462766965e-28	DOWN	-10.9557280760217	2.07414531367337e-27	cGMP-PKG signaling pathway: ATP1B4
hsa04213__61	6.63199060991518e-28	DOWN	-10.9503243629355	2.19779724092251e-27	Longevity regulating pathway - multiple species: ATG5
hsa05214__52	7.22860633662965e-28	UP	10.9425189995888	2.39129424410689e-27	Glioma: E2F1*
hsa05200__200	7.25258657775213e-28	DOWN	-10.9422187933062	2.39501057637895e-27	Pathways in cancer: FIGF
hsa05145__35	8.58612432565801e-28	UP	10.9269082728952	2.83040835226516e-27	Toxoplasmosis: CASP3
hsa04151__24	8.70046079941401e-28	DOWN	-10.925707447765	2.86307632961452e-27	PI3K-Akt signaling pathway: MYC
hsa04540__22	8.81614311264925e-28	DOWN	-10.9245066226347	2.89607218683006e-27	Gap junction: C00547
hsa05016__52	1.00291158925529e-27	UP	10.9127985776146	3.28877988867485e-27	Huntington's disease: CASP3
hsa04022__51	1.00955879991614e-27	DOWN	-10.9121981650494	3.30481007847113e-27	cGMP-PKG signaling pathway: GTF2I
hsa05164__20	1.13321791806145e-27	DOWN	-10.9016909451596	3.70315907484775e-27	Influenza A: ATF2
hsa05221__21	1.24697176298165e-27	DOWN	-10.8929849629651	4.06781240042103e-27	Acute myeloid leukemia: PIM1
hsa04976__41	1.36751936429604e-27	DOWN	-10.8845791870532	4.4533256248046e-27	Bile secretion: CYP7A1
hsa05030__37	1.39943091115747e-27	DOWN	-10.8824777430752	4.54936104163475e-27	Cocaine addiction: PRKACA
hsa04933__21	1.58072802442593e-27	DOWN	-10.8713701106202	5.1298583037933e-27	AGE-RAGE signaling pathway in diabetic complications: SMAD4
hsa04024__31	1.65524262560355e-27	DOWN	-10.8671672226643	5.35318570311373e-27	cAMP signaling pathway: C00165
hsa04024__32	1.65524262560355e-27	DOWN	-10.8671672226643	5.35318570311373e-27	cAMP signaling pathway: C01245
hsa04728__24	1.9638011064866e-27	DOWN	-10.8515564959708	6.34017573726515e-27	Dopaminergic synapse: SLC6A3
hsa04950__31	1.98977331052238e-27	UP	10.8503556708405	6.41300866290148e-27	Maturity onset diabetes of the young: NKX6-1*
hsa04723__73	2.14586119585429e-27	DOWN	-10.8434509263415	6.89243279830805e-27	Retrograde endocannabinoid signaling: MAPK14*
hsa04723__68	2.14586119585429e-27	DOWN	-10.8434509263415	6.89243279830805e-27	Retrograde endocannabinoid signaling: MAPK14
hsa04390__88	2.21019221908445e-27	DOWN	-10.8407490697983	7.08694740556259e-27	Hippo signaling pathway: ID1
hsa05160__53	2.3678315048743e-27	UP	10.8344447378644	7.56659081234491e-27	Hepatitis C: EIF2S1
hsa05162__74	2.3678315048743e-27	UP	10.8344447378644	7.56659081234491e-27	Measles: EIF2S1
hsa05321__55	2.39124343004784e-27	DOWN	-10.8335441190167	7.62843192709657e-27	Inflammatory bowel disease (IBD): IL4*
hsa04922__51	2.56168055810259e-27	DOWN	-10.8272397870828	8.15830130283857e-27	Glucagon signaling pathway: G6PC
hsa04919__32	2.62112799174874e-27	DOWN	-10.8251383431048	8.33350168611824e-27	Thyroid hormone signaling pathway: PLN
hsa04742__4	2.80780267394141e-27	UP	10.8188340111709	8.91192774381066e-27	Taste transduction: TRPM5
hsa04923__26 27	2.83548896941777e-27	DOWN	-10.8179333923232	8.98462693682292e-27	Regulation of lipolysis in adipocytes: PNPLA2 ABHD5
hsa04724__68	3.55366661615849e-27	DOWN	-10.797219158826	1.12413124103734e-26	Glutamatergic synapse: MAPK1
hsa05164__78	3.74442322293128e-27	UP	10.792415858305	1.18248256065343e-26	Influenza A: GSK3B
hsa04390__52	6.16638545254454e-27	DOWN	-10.7464842970721	1.94406682304215e-26	Hippo signaling pathway: ITGB2
hsa04024__108	6.47472809869883e-27	UP	10.7419812028336	2.03785830778142e-26	cAMP signaling pathway: AMH
hsa04010__119	6.49581950851411e-27	DOWN	-10.741680996551	2.04107773520034e-26	MAPK signaling pathway: NFATC3
hsa04924__23	6.86497637018193e-27	DOWN	-10.7365774897474	2.15347088473654e-26	Renin secretion: ITPR1
hsa04550__22	8.20778061682336e-27	DOWN	-10.7200661442062	2.57040329650185e-26	Signaling pathways regulating pluripotency of stem cells: SMAD2
hsa04270__28	8.36917481070773e-27	DOWN	-10.7182649065108	2.61658560221628e-26	Vascular smooth muscle contraction: KCNMB2
hsa04024__111	9.55947524737929e-27	DOWN	-10.7059564489255	2.9837631212335e-26	cAMP signaling pathway: JUN
hsa04014__42	1.07420906545597e-26	DOWN	-10.6951490227531	3.34732808290509e-26	Ras signaling pathway: PLA2G4B
hsa04723__40	1.68345065983581e-26	DOWN	-10.6534203494762	5.21980823404535e-26	Retrograde endocannabinoid signaling: GRIA1
hsa04724__4	1.68345065983581e-26	DOWN	-10.6534203494762	5.21980823404535e-26	Glutamatergic synapse: GRIA1
hsa05031__12	1.68345065983581e-26	DOWN	-10.6534203494762	5.21980823404535e-26	Amphetamine addiction: GRIA1
hsa04152__68	1.73303632775386e-26	DOWN	-10.6507184929331	5.36470388772572e-26	AMPK signaling pathway: PPARGC1A**
hsa04520__34	1.7956024641495e-26	DOWN	-10.6474162238248	5.5492385364094e-26	Adherens junction: RHOA
hsa04115__39	1.86042519780705e-26	UP	10.6441139547166	5.7401296332996e-26	p53 signaling pathway: BAX
hsa04610__44	2.03606028235173e-26	DOWN	-10.6357081788047	6.27173323039163e-26	Complement and coagulation cascades: C3
hsa04972__51	2.32329642266901e-26	DOWN	-10.6233997212194	7.14480192830618e-26	Pancreatic secretion: CLCA1
hsa05164__68	2.77259553528818e-26	UP	10.6068883756782	8.51259315491258e-26	Influenza A: EIF2S1
hsa05031__55	3.17278695939895e-26	DOWN	-10.5942797118104	9.72539428500919e-26	Amphetamine addiction: GRIA1*
hsa04750__59	3.25526514119263e-26	DOWN	-10.5918780615498	9.96195960961068e-26	Inflammatory mediator regulation of TRP channels: TRPV2
hsa04620__22	3.7244252415786e-26	UP	10.579269397682	1.13791789088231e-25	Toll-like receptor signaling pathway: CD86
hsa04728__32	4.38500434226529e-26	DOWN	-10.563958877271	1.33756869466177e-25	Dopaminergic synapse: CREB3
hsa05205__81	7.4013790901895e-26	UP	10.5147250469299	2.25400183313875e-25	Proteoglycans in cancer: CTTN
hsa05142__21	7.47242620249727e-26	DOWN	-10.5138244280822	2.27195612208614e-25	Chagas disease (American trypanosomiasis): TICAM1
hsa04010__86	7.91312845077183e-26	UP	10.508420714996	2.40206273974156e-25	MAPK signaling pathway: MAP4K2
hsa04919__45	8.45992805533049e-26	DOWN	-10.5021163830621	2.56390400257516e-25	Thyroid hormone signaling pathway: SLC9A1
hsa03320__39	8.67794349105233e-26	UP	10.4997147328016	2.62574167788846e-25	PPAR signaling pathway: MMP1
hsa04623__8	1.31942808919447e-25	UP	10.4600875035026	3.98586073890099e-25	Cytosolic DNA-sensing pathway: TBK1
hsa04722__38	1.37925892529641e-25	DOWN	-10.4558846155467	4.15991576345417e-25	Neurotrophin signaling pathway: ATF4
hsa04014__65	1.39242551590743e-25	DOWN	-10.454983996699	4.19289670575331e-25	Ras signaling pathway: MLLT4*
hsa04730__8	1.49759486439913e-25	DOWN	-10.4480792521999	4.50236920032955e-25	Long-term depression: GNA13*
hsa04621__21 30	1.58035336484476e-25	DOWN	-10.4429757453963	4.74358462067621e-25	NOD-like receptor signaling pathway: NLRP3 PYCARD
hsa04340__17	2.02843799833794e-25	UP	10.4192594490734	6.07884369836839e-25	Hedgehog signaling pathway: SMO
hsa04921__80	2.38993696557183e-25	DOWN	-10.4036487223799	7.15078273616156e-25	Oxytocin signaling pathway: KCNJ2
hsa04068__47	2.52939532300564e-25	DOWN	-10.3982450092937	7.5440219236946e-25	FoxO signaling pathway: GADD45G
hsa04068__54	2.52939532300564e-25	DOWN	-10.3982450092937	7.5440219236946e-25	FoxO signaling pathway: GADD45G*
hsa04911__24	3.10352093517285e-25	DOWN	-10.3787316009268	9.24170497177462e-25	Insulin secretion: INS
hsa05100__33	3.23297691348387e-25	UP	10.3748289192534	9.61196775385473e-25	Bacterial invasion of epithelial cells: DNM1
hsa05168__39 40	3.42110046574826e-25	UP	10.3694252061672	1.0155209755357e-24	Herpes simplex infection: POU2F3 HCFC2
hsa04932__138	3.7238064271589e-25	DOWN	-10.3613196365379	1.10363285120372e-24	Non-alcoholic fatty liver disease (NAFLD): CEBPA
hsa05211__4	4.02768639799025e-25	UP	10.3538144794737	1.1918146050116e-24	Renal cell carcinoma: SLC2A1
hsa05132__41	4.15600528497474e-25	UP	10.350812416648	1.22785124692886e-24	Salmonella infection: ACTB*
hsa05132__8	6.14620236684618e-25	DOWN	-10.3132866313271	1.81298496817959e-24	Salmonella infection: TJP1
hsa04360__58	6.7710471633847e-25	UP	10.3039802365675	1.99416890595609e-24	Axon guidance: PLXNC1
hsa04210__50	6.81345506995388e-25	DOWN	-10.3033798240024	2.00351832182212e-24	Apoptosis: SPTA1
hsa05132__86	7.29767113773409e-25	DOWN	-10.2967752857859	2.14255063559412e-24	Salmonella infection: MYH9
hsa04015__82	8.63558190343639e-25	DOWN	-10.2805641465272	2.53139756576552e-24	Rap1 signaling pathway: ITGA2B
hsa04022__37 38	1.14969941315802e-24	DOWN	-10.252945168531	3.36493021390019e-24	cGMP-PKG signaling pathway: ATP2A1 PLN
hsa04670__76	1.23482720190425e-24	UP	10.2460404240319	3.6084608279597e-24	Leukocyte transendothelial migration: CDC42
hsa05152__129	1.29367978915636e-24	UP	10.2415373297934	3.77457193140497e-24	Tuberculosis: IFNB1
hsa04933__26	1.65776372934467e-24	DOWN	-10.217520827188	4.82936131385834e-24	AGE-RAGE signaling pathway in diabetic complications: IL6
hsa05169__79	1.76909705329896e-24	DOWN	-10.2112164952541	5.145717280416e-24	Epstein-Barr virus infection: ATF2
hsa05031__10	1.9652578162671e-24	DOWN	-10.2010094816468	5.69864110612018e-24	Amphetamine addiction: CACNA1C
hsa05031__53	1.9652578162671e-24	DOWN	-10.2010094816468	5.69864110612018e-24	Amphetamine addiction: CACNA1C*
hsa04024__118	2.03951498519396e-24	DOWN	-10.197407006256	5.90485155189438e-24	cAMP signaling pathway: MYL9
hsa04020__16	2.10351416724386e-24	UP	10.1944049434303	6.08077403115572e-24	Calcium signaling pathway: C06124
hsa04620__39	2.30769172825388e-24	DOWN	-10.1853987549533	6.6607569237927e-24	Toll-like receptor signaling pathway: IL6
hsa05210__40	2.57875772152169e-24	UP	10.1745913287809	7.4317266238332e-24	Colorectal cancer: CASP9
hsa04068__41	2.80254192265919e-24	DOWN	-10.1664857591515	8.06428219399175e-24	FoxO signaling pathway: CDKN2B
hsa05222__36	2.8460458990271e-24	DOWN	-10.1649847277387	8.17694226952893e-24	Small cell lung cancer: PTGS2
hsa05212__54	3.24888247947646e-24	DOWN	-10.1520758575883	9.32007660906301e-24	Pancreatic cancer: C00416
hsa04976__37	3.31947518404104e-24	DOWN	-10.1499744136103	9.50806992502e-24	Bile secretion: ABCB11
hsa04919__46	3.44440845817613e-24	DOWN	-10.1463719382195	9.85090333776705e-24	Thyroid hormone signaling pathway: ATP1B4
hsa04064__129	3.53018159247137e-24	DOWN	-10.143970287959	1.0080868103729e-23	NF-kappa B signaling pathway: PTGS2
hsa04923__52 53	3.5410509160056e-24	DOWN	-10.1436700816764	1.00965624752269e-23	Regulation of lipolysis in adipocytes: PNPLA2 ABHD5*
hsa04919__103	4.04115421773582e-24	DOWN	-10.130761211526	1.15050435986752e-23	Thyroid hormone signaling pathway: CCND1
hsa04911__25	5.96403010648239e-24	DOWN	-10.0926350136399	1.69537255220581e-23	Insulin secretion: PRKCA
hsa04261__3	6.34019103514982e-24	DOWN	-10.0866308879886	1.799579902575e-23	Adrenergic signaling in cardiomyocytes: RYR2
hsa04213__54	6.57706915939075e-24	DOWN	-10.0830284125977	1.86399893672628e-23	Longevity regulating pathway - multiple species: SOD2*
hsa04066__5	6.90659212614906e-24	DOWN	-10.0782251120767	1.95444075377019e-23	HIF-1 signaling pathway: VEGFA
hsa04924__31	7.09802238442173e-24	DOWN	-10.0755232555336	2.00559158801931e-23	Renin secretion: C02135
hsa04010__79	8.29455617717889e-24	UP	10.0602127351226	2.34016081935723e-23	MAPK signaling pathway: HSPB1
hsa04670__54	1.00495989591688e-23	UP	10.0412997393208	2.83106393467439e-23	Leukocyte transendothelial migration: RAC1*
hsa04022__46	1.02036995352057e-23	DOWN	-10.039798707908	2.87017236925921e-23	cGMP-PKG signaling pathway: VASP
hsa05222__44	1.23955659896944e-23	UP	10.0205855058237	3.48150500667201e-23	Small cell lung cancer: RB1
hsa04064__134	1.24332753021369e-23	DOWN	-10.0202852995411	3.48688422279332e-23	NF-kappa B signaling pathway: CCL21
hsa04723__9	1.25852519896856e-23	DOWN	-10.0190844744108	3.51377243515887e-23	Retrograde endocannabinoid signaling: PRKCA
hsa04725__20	1.25852519896856e-23	DOWN	-10.0190844744108	3.51377243515887e-23	Cholinergic synapse: PRKCA
hsa04726__18	1.25852519896856e-23	DOWN	-10.0190844744108	3.51377243515887e-23	Serotonergic synapse: PRKCA
hsa05160__55	1.35365216466782e-23	UP	10.0118795236292	3.77375729586177e-23	Hepatitis C: MAPK14
hsa04923__43	1.69923830523909e-23	DOWN	-9.98936405243665	4.73017596376926e-23	Regulation of lipolysis in adipocytes: C00219
hsa04925__33	1.86640591761188e-23	DOWN	-9.98005765767706	5.1878353834212e-23	Aldosterone synthesis and secretion: CYP11B2
hsa04670__55	1.8834229121137e-23	UP	9.97915703882936	5.22740273539387e-23	Leukocyte transendothelial migration: RAC2
hsa04022__48	1.91791915142129e-23	DOWN	-9.97735580113395	5.31529511138731e-23	cGMP-PKG signaling pathway: SLC8A2
hsa04550__53 64	2.01909296133409e-23	DOWN	-9.9722522943303	5.58744576487003e-23	Signaling pathways regulating pluripotency of stem cells: SMAD1 SMAD4
hsa04622__44	2.42027365826703e-23	UP	9.95423991737625	6.68778559394668e-23	RIG-I-like receptor signaling pathway: MAPK8
hsa04550__17	3.28126530580881e-23	DOWN	-9.92391908283692	9.05359399356058e-23	Signaling pathways regulating pluripotency of stem cells: AKT3
hsa04740__37	3.36119647879235e-23	UP	9.92151743257638	9.26053985872555e-23	Olfactory transduction: CNGB1*
hsa04910__24	3.46382627871989e-23	DOWN	-9.9185153697507	9.52932588245194e-23	Insulin signaling pathway: ACACA
hsa04024__109	3.72297031574036e-23	DOWN	-9.91131041896908	1.02272824901698e-22	cAMP signaling pathway: BDNF
hsa05231__39	3.74541278111083e-23	UP	9.91071000640394	1.02739133076018e-22	Choline metabolism in cancer: EIF4EBP1
hsa05134__70	4.64901074905778e-23	DOWN	-9.88909515405908	1.27339521829148e-22	Legionellosis: IL6
hsa05200__209	5.0560077212267e-23	DOWN	-9.88068937814718	1.38285858925546e-22	Pathways in cancer: FIGF**
hsa04068__57	5.13231088268817e-23	DOWN	-9.87918834673435	1.40168781229231e-22	FoxO signaling pathway: IL7R
hsa05221__35	5.87241026975898e-23	UP	9.86567906401881	1.60148895455401e-22	Acute myeloid leukemia: EIF4EBP1
hsa05142__36	7.15285539644911e-23	DOWN	-9.84586544936935	1.94785728839535e-22	Chagas disease (American trypanosomiasis): SMAD2
hsa05030__78	7.48039919866782e-23	DOWN	-9.84136235513083	2.03410565764064e-22	Cocaine addiction: GRIA2
hsa05160__15 16	7.77625224789923e-23	DOWN	-9.83745967345745	2.11149970719692e-22	Hepatitis C: TRAF6 RIPK1
hsa04012__8	1.13837306181596e-22	DOWN	-9.7990332692888	3.086584391273e-22	ErbB signaling pathway: STAT5A
hsa04014__55	1.19734472786285e-22	DOWN	-9.79392976248515	3.24180222428574e-22	Ras signaling pathway: MLLT4
hsa04022__44	1.22613275270626e-22	DOWN	-9.79152811222461	3.31496898177706e-22	cGMP-PKG signaling pathway: BAD
hsa04010__120	1.26308292644899e-22	DOWN	-9.78852604939893	3.40996094654835e-22	MAPK signaling pathway: NFATC1
hsa04726__16	1.32058437581728e-22	DOWN	-9.78402295516042	3.55498286842504e-22	Serotonergic synapse: ITPR1
hsa04726__46	1.32058437581728e-22	DOWN	-9.78402295516042	3.55498286842504e-22	Serotonergic synapse: ITPR1*
hsa04151__98	1.65421724671223e-22	UP	9.76120727768528	4.44674421541098e-22	PI3K-Akt signaling pathway: BCL2L1*
hsa05169__29	1.69385814912498e-22	DOWN	-9.75880562742474	4.54679923172263e-22	Epstein-Barr virus infection: FCER2
hsa05120__19	1.84015003111239e-22	DOWN	-9.75039985151285	4.93244209480767e-22	Epithelial cell signaling in Helicobacter pylori infection: CXCL1
hsa04510__42	2.53871577744947e-22	UP	9.71767736671298	6.79522356955493e-22	Focal adhesion: BIRC2
hsa04933__24	2.63010123045665e-22	DOWN	-9.71407489132217	7.02981537984074e-22	AGE-RAGE signaling pathway in diabetic complications: THBD
hsa04152__56	3.86608915187458e-22	UP	9.67474786830582	1.03187237448471e-21	AMPK signaling pathway: FASN
hsa05161__195	4.2465656274538e-22	DOWN	-9.66514126726365	1.13181515091996e-21	Hepatitis B: IL6
hsa04917__40	4.30927232071505e-22	UP	9.66364023585082	1.14690123096651e-21	Prolactin signaling pathway: TH
hsa04911__56	4.34733527035305e-22	DOWN	-9.66273961700311	1.15539504568506e-21	Insulin secretion: CAMK2A*
hsa05145__13	5.5592859759453e-22	UP	9.63752228926744	1.47540937129961e-21	Toxoplasmosis: GNAI1
hsa04932__96	6.30351141999425e-22	DOWN	-9.62461341911703	1.6705638869068e-21	Non-alcoholic fatty liver disease (NAFLD): IL6*
hsa04911__4	6.34042893267998e-22	DOWN	-9.62401300655189	1.67798112176136e-21	Insulin secretion: CACNA1C
hsa04971__49	6.80048195578296e-22	DOWN	-9.61680805577027	1.79720191208385e-21	Gastric acid secretion: KCNJ1
hsa04012__22	7.23002516155607e-22	UP	9.61050372383635	1.90803613462976e-21	ErbB signaling pathway: EIF4EBP1
hsa04530__11 20 16	8.96886269141475e-22	DOWN	-9.58828845892635	2.36360350591421e-21	Tight junction: TJP1 ACTB CTTN
hsa04917__37	1.01927040069639e-21	UP	9.57507938249338	2.68236566233686e-21	Prolactin signaling pathway: TNFSF11
hsa04330__12	1.02520973921856e-21	DOWN	-9.57447896992824	2.69422251747088e-21	Notch signaling pathway: HES1
hsa04540__16 17	1.19570485496617e-21	DOWN	-9.55856803695216	3.13789025486233e-21	Gap junction: GJA1 GJA1**
hsa04213__13	1.25248360332412e-21	DOWN	-9.55376473643108	3.28231058667506e-21	Longevity regulating pathway - multiple species: RPS6KB1*
hsa04151__73	1.31192856680706e-21	DOWN	-9.54896143590999	3.42853098335252e-21	PI3K-Akt signaling pathway: MAPK1
hsa04910__46	1.31192856680706e-21	DOWN	-9.54896143590999	3.42853098335252e-21	Insulin signaling pathway: FBP1
hsa04727__17 37	1.3157351990317e-21	DOWN	-9.54866122962743	3.433703387473e-21	GABAergic synapse: GABRA1 GPHN
hsa04370__25	1.35440767896468e-21	DOWN	-9.54565916680175	3.52972542132405e-21	VEGF signaling pathway: PXN
hsa04810__32	1.35833623392613e-21	DOWN	-9.54535896051918	3.53506064203213e-21	Regulation of actin cytoskeleton: PXN
hsa04014__30	1.672910586101e-21	DOWN	-9.52374410817432	4.34771644714215e-21	Ras signaling pathway: C01245
hsa04370__14	2.0832730032044e-21	DOWN	-9.50092843069918	5.40672648207329e-21	VEGF signaling pathway: PTGS2
hsa04931__137	2.34450307441482e-21	DOWN	-9.48861997311391	6.0763052094144e-21	Insulin resistance: MLXIP*
hsa05152__90	2.45501047465287e-21	DOWN	-9.48381667259283	6.35394584279993e-21	Tuberculosis: CR1
hsa04210__63	3.54590213015327e-21	DOWN	-9.44539026842418	9.16471816032737e-21	Apoptosis: FAS*
hsa04740__16	3.72293527390995e-21	DOWN	-9.44028676162053	9.60905958746811e-21	Olfactory transduction: PRKG1
hsa04350__12	3.91991508655408e-21	DOWN	-9.43488304853431	1.01035945783746e-20	TGF-beta signaling pathway: ACVR2A
hsa05164__23	4.78888232936644e-21	UP	9.41386860875458	1.23264519135336e-20	Influenza A: IRF3
hsa04151__99	5.26214248621503e-21	UP	9.40396180142985	1.35260817121724e-20	PI3K-Akt signaling pathway: MYB
hsa04115__20	5.41448100534751e-21	UP	9.40095973860417	1.38986472801202e-20	p53 signaling pathway: RRM2B
hsa05020__59	5.42995267635809e-21	DOWN	-9.4006595323216	1.39193466287542e-20	Prion diseases: CCL5
hsa05214__27	6.01702502618202e-21	DOWN	-9.38985210614917	1.53822993526476e-20	Glioma: MTOR
hsa05214__48	6.01702502618202e-21	DOWN	-9.38985210614917	1.53822993526476e-20	Glioma: MTOR*
hsa04914__15	6.08601046343124e-21	UP	9.3886512810189	1.55375185608523e-20	Progesterone-mediated oocyte maturation: ANAPC10
hsa05020__48	7.84024165699626e-21	DOWN	-9.36193292187038	1.9988892908407e-20	Prion diseases: SOD1
hsa04151__100	8.93431935529899e-21	DOWN	-9.34812343287228	2.27474065970282e-20	PI3K-Akt signaling pathway: PRKCA
hsa04930__26	9.42910244589795e-21	UP	9.34241951350349	2.39746732014104e-20	Type II diabetes mellitus: INS*
hsa04360__59	1.00075338303931e-20	UP	9.33611518156957	2.54110217125793e-20	Axon guidance: MAPK1*
hsa04024__59	1.21321117197919e-20	DOWN	-9.31570115435498	3.07641537402011e-20	cAMP signaling pathway: MLLT4
hsa04530__13 45 20	1.44140676655205e-20	DOWN	-9.29738857111835	3.65013923767022e-20	Tight junction: EPB41 TJP2 ACTB
hsa04022__71	1.84719730810985e-20	UP	9.2709704182524	4.67144514392786e-20	cGMP-PKG signaling pathway: PPIF
hsa04742__49	2.00423417128552e-20	UP	9.26226443605794	5.06176882774931e-20	Taste transduction: HTR1A
hsa04930__9	3.73362145615943e-20	UP	9.19561864132794	9.41674458540075e-20	Type II diabetes mellitus: C00238
hsa04728__54	3.83935118715452e-20	DOWN	-9.19261657850226	9.67043013493745e-20	Dopaminergic synapse: CAMK2A
hsa04340__52	4.15134435858231e-20	DOWN	-9.18421080259037	1.04422704816281e-19	Hedgehog signaling pathway: BCL2*
hsa04725__43	5.20205812335609e-20	DOWN	-9.15989409370239	1.30677369168263e-19	Cholinergic synapse: CREB3
hsa04723__10	5.94458320227255e-20	UP	9.14548419213915	1.48931624494268e-19	Retrograde endocannabinoid signaling: CACNA1A
hsa04723__21	5.94458320227255e-20	UP	9.14548419213915	1.48931624494268e-19	Retrograde endocannabinoid signaling: CACNA1A*
hsa04210__114	6.18024355783607e-20	DOWN	-9.1412813041832	1.54629529230013e-19	Apoptosis: HRK
hsa04152__62	6.71676933361939e-20	UP	9.13227511570618	1.67829914599346e-19	AMPK signaling pathway: EIF4EBP1
hsa04530__20 22	7.04097362269125e-20	DOWN	-9.12717160890253	1.75697070876983e-19	Tight junction: ACTB MYL12B
hsa04012__37 7	7.15905268822728e-20	DOWN	-9.12537037120712	1.78406631315372e-19	ErbB signaling pathway: ERBB3 ERBB3
hsa04520__44 47	7.23885724656892e-20	DOWN	-9.12416954607685	1.80156460480834e-19	Adherens junction: ACTB TJP1
hsa05205__77	8.45285303018003e-20	DOWN	-9.10735799425307	2.10091413276565e-19	Proteoglycans in cancer: MIR21
hsa04310__35	9.10815045520814e-20	DOWN	-9.09925242462374	2.26079454495853e-19	Wnt signaling pathway: JUN
hsa04151__36	9.94994653481184e-20	DOWN	-9.08964582358158	2.46648410803581e-19	PI3K-Akt signaling pathway: PCK1
hsa05032__25	1.01721368243845e-19	DOWN	-9.08724417332104	2.51824046021324e-19	Morphine addiction: C00575*
hsa05219__21	1.03705711849413e-19	UP	9.08514272934306	2.56398727059273e-19	Bladder cancer: RB1
hsa05205__120	1.18056437894299e-19	UP	9.07103303406239	2.91495462290917e-19	Proteoglycans in cancer: PLAU
hsa05140__26	1.21020316672155e-19	DOWN	-9.06833117751928	2.98421489536718e-19	Leishmaniasis: C00533
hsa04612__39	1.22024524811689e-19	UP	9.06743055867158	3.00503384169283e-19	Antigen processing and presentation: PSME3
hsa04360__81	1.23716535959839e-19	DOWN	-9.06592952725874	3.04271428100179e-19	Axon guidance: FYN*
hsa04913__21	1.64215229442864e-19	DOWN	-9.03500828015428	4.02820386583737e-19	Ovarian steroidogenesis: CYP17A1
hsa04913__22	1.64215229442864e-19	DOWN	-9.03500828015428	4.02820386583737e-19	Ovarian steroidogenesis: CYP17A1*
hsa04380__68	1.70646836477177e-19	DOWN	-9.03080539219833	4.18051376454517e-19	Osteoclast differentiation: TGFBR1
hsa05014__32 34	1.73003649411158e-19	DOWN	-9.02930436078549	4.23273251619227e-19	Amyotrophic lateral sclerosis (ALS): NEFM PRPH
hsa05133__60	2.36381205216235e-19	UP	8.99508084457279	5.77581644475039e-19	Pertussis: C5
hsa04062__42	2.6583597348636e-19	UP	8.98217197442238	6.4870882361152e-19	Chemokine signaling pathway: PAK1
hsa04611__43	2.71702966521564e-19	DOWN	-8.97977032416184	6.62165854856056e-19	Platelet activation: MYL12B
hsa05200__186	2.98098255593486e-19	DOWN	-8.96956331055454	7.2555261950798e-19	Pathways in cancer: PTCH1*
hsa04350__11	3.17374624841111e-19	DOWN	-8.96265856605549	7.71470789232145e-19	TGF-beta signaling pathway: SMAD4*
hsa04724__51	3.19978046715526e-19	UP	8.96175794720778	7.76794250359785e-19	Glutamatergic synapse: ADRBK1
hsa04726__72	3.36047575140254e-19	UP	8.95635423412157	8.14752766049726e-19	Serotonergic synapse: KCNJ3
hsa04151__109	3.39725449730616e-19	UP	8.9551534089913	8.22608402118335e-19	PI3K-Akt signaling pathway: RXRA
hsa05217__5	3.40651114847594e-19	DOWN	-8.95485320270873	8.23788217244053e-19	Basal cell carcinoma: BMP2
hsa05231__59	3.82902066297088e-19	DOWN	-8.94194433255832	9.24772471172529e-19	Choline metabolism in cancer: PLA2G4B
hsa04530__11 62	3.98826586644105e-19	DOWN	-8.93744123831981	9.61996349556191e-19	Tight junction: TJP1 SHROOM1
hsa04728__68	4.409587730561e-19	DOWN	-8.92633360586481	1.06225837765694e-18	Dopaminergic synapse: CACNA1C
hsa04062__59	4.48193464515272e-19	DOWN	-8.9245323681694	1.07830412269423e-18	Chemokine signaling pathway: FOXO3
hsa04010__62	4.94130279294142e-19	DOWN	-8.91372494199697	1.18730280664155e-18	MAPK signaling pathway: MEF2C
hsa04623__17	5.2446100303207e-19	UP	8.90712040378048	1.25857244533494e-18	Cytosolic DNA-sensing pathway: NFKB1
hsa04917__38	5.34491976749437e-19	UP	8.90501895980251	1.28100819427575e-18	Prolactin signaling pathway: IRF1
hsa04666__23	6.16846807716505e-19	UP	8.88910802682643	1.47650337796091e-18	Fc gamma R-mediated phagocytosis: RPS6KB1
hsa05132__55	7.07884401535113e-19	UP	8.87379750641548	1.69225800316091e-18	Salmonella infection: IL18
hsa05014__33 34	7.15561736452037e-19	DOWN	-8.87259668128521	1.70843774179591e-18	Amyotrophic lateral sclerosis (ALS): NEFH PRPH
hsa04340__33	7.2723219815735e-19	DOWN	-8.8707954435898	1.7340980968752e-18	Hedgehog signaling pathway: HHIP*
hsa04725__61	8.75733381945188e-19	DOWN	-8.85008121009264	2.08555516435362e-18	Cholinergic synapse: FOS
hsa04010__117	1.08277967519223e-18	UP	8.8263649137698	2.57537089833696e-18	MAPK signaling pathway: JUND
hsa05161__126	1.08860502425842e-18	DOWN	-8.82576450120466	2.58595302222702e-18	Hepatitis B: MYC*
hsa05150__40	1.15167120399926e-18	UP	8.81946016927074	2.73231084888208e-18	Staphylococcus aureus infection: FCGR1A
hsa04360__145	1.46148808849036e-18	DOWN	-8.79274181012223	3.46297114536367e-18	Axon guidance: ABLIM3
hsa04921__34 35	1.63936288570427e-18	DOWN	-8.77983293997182	3.87955020433037e-18	Oxytocin signaling pathway: MYL9 ACTB
hsa04922__70	1.67027623573386e-18	DOWN	-8.77773149599385	3.94773465024392e-18	Glucagon signaling pathway: PFKFB1
hsa04261__15 17	1.70631109443141e-18	DOWN	-8.77532984573331	4.02783736989525e-18	Adrenergic signaling in cardiomyocytes: ACTC1 MYH6
hsa04660__34	2.01823761335235e-18	DOWN	-8.75641684993155	4.75817876472907e-18	T cell receptor signaling pathway: FOS
hsa04710__23	2.13423818448864e-18	UP	8.75011251799763	5.02535532412802e-18	Circadian rhythm: BHLHE41
hsa04530__4 37 11	2.58420455546936e-18	UP	8.72849766565276	6.07724700841918e-18	Tight junction: OCLN TJP3 TJP1
hsa04152__53	2.6256782534555e-18	UP	8.72669642795736	6.1670617978036e-18	AMPK signaling pathway: G6PC
hsa04360__111	2.75408293749415e-18	DOWN	-8.72129271487114	6.46057657871599e-18	Axon guidance: RHOA***
hsa04115__24	2.78344858783882e-18	DOWN	-8.72009188974087	6.52132156676951e-18	p53 signaling pathway: SERPINB5
hsa05161__69	3.05394333326289e-18	UP	8.709584669851	7.14615133648939e-18	Hepatitis B: SMAD4
hsa04360__51	3.23708564121529e-18	DOWN	-8.70298013163452	7.56527850726808e-18	Axon guidance: FYN
hsa04725__18	3.32387681051044e-18	DOWN	-8.69997806880884	7.75846525086846e-18	Cholinergic synapse: ITPR1
hsa04932__55	5.50016605884862e-18	UP	8.64263866883843	1.28223474250329e-17	Non-alcoholic fatty liver disease (NAFLD): CASP3
hsa04210__72	5.79692918231536e-18	UP	8.63663454318708	1.34974348619214e-17	Apoptosis: BCL2A1
hsa04919__38	6.37146027785244e-18	DOWN	-8.62582711701465	1.48167993342633e-17	Thyroid hormone signaling pathway: TP53
hsa04210__64	6.96552593735551e-18	DOWN	-8.61562010340735	1.61782734688393e-17	Apoptosis: TNFRSF10D*
hsa04933__35	8.2574014289319e-18	DOWN	-8.59610669504045	1.91551324505716e-17	AGE-RAGE signaling pathway in diabetic complications: CCND1
hsa04012__43	8.7232934958839e-18	DOWN	-8.58980236310654	2.02109352389221e-17	ErbB signaling pathway: PTK2
hsa04950__21	9.16711513398607e-18	UP	8.58409844373775	2.12130656856648e-17	Maturity onset diabetes of the young: PKLR
hsa05140__43	1.12347636565491e-17	UP	8.56068235369748	2.59657083771904e-17	Leishmaniasis: MAPK14
hsa04014__70	1.15913093247082e-17	UP	8.55707987830667	2.67568430234972e-17	Ras signaling pathway: RIN1*
hsa04510__23 4 5	1.16215206233793e-17	DOWN	-8.5567796720241	2.67936653390548e-17	Focal adhesion: TLN1 ITGB1 ITGA11
hsa05205__150	1.22742113429474e-17	DOWN	-8.55047534009018	2.82637783252428e-17	Proteoglycans in cancer: PRKCA
hsa04071__24	1.26632888697597e-17	DOWN	-8.54687286469937	2.91240144262895e-17	Sphingolipid signaling pathway: PTEN
hsa05152__76	1.48372635826809e-17	UP	8.52856028146275	3.4082173926476e-17	Tuberculosis: TNF*
hsa04010__67	1.54659935249259e-17	UP	8.52375698094166	3.54830303215333e-17	MAPK signaling pathway: ELK1
hsa04330__19	1.72442293590813e-17	UP	8.51114831707383	3.95145206898949e-17	Notch signaling pathway: DTX2
hsa04742__47	1.75142030051649e-17	DOWN	-8.50934707937842	4.00842721640742e-17	Taste transduction: GABRA1
hsa04910__26	1.75596083374854e-17	UP	8.50904687309585	4.01392993505293e-17	Insulin signaling pathway: RPS6
hsa04390__74	2.10436482804596e-17	DOWN	-8.48803243331612	4.80449758432365e-17	Hippo signaling pathway: AXIN1
hsa04530__20 31	2.20446627076643e-17	DOWN	-8.4826287202299	5.02693218782782e-17	Tight junction: ACTB MLLT4
hsa05222__40	2.40653210296413e-17	UP	8.47242170662261	5.48105917753892e-17	Small cell lung cancer: TRAF1
hsa04014__97	2.5078413821154e-17	UP	8.46761840610153	5.70488372517535e-17	Ras signaling pathway: PAK4
hsa05133__59	2.53381918576733e-17	UP	8.46641758097125	5.75700876669507e-17	Pertussis: C3
hsa04510__26 4 5	2.6133560235313e-17	DOWN	-8.46281510558044	5.93055068625037e-17	Focal adhesion: ACTN4 ITGB1 ITGA11
hsa04620__66	2.64041178126676e-17	UP	8.46161428045017	5.98472103377593e-17	Toll-like receptor signaling pathway: CASP8
hsa05110__17	2.65404310233776e-17	DOWN	-8.46101386788504	6.00836986661766e-17	Vibrio cholerae infection: C00698*
hsa04210__73	2.95688734704265e-17	UP	8.4484052040172	6.68591013849956e-17	Apoptosis: TRAF1
hsa04510__6 4 5	3.07310809801478e-17	DOWN	-8.44390210977869	6.94034869731944e-17	Focal adhesion: FLNA ITGB1 ITGA11
hsa04550__60	3.1611896779721e-17	UP	8.44059984067044	7.1307027669983e-17	Signaling pathways regulating pluripotency of stem cells: MAPK14
hsa05223__22	3.27690323898978e-17	UP	8.4363969527145	7.38285513916284e-17	Non-small cell lung cancer: BAD*
hsa05031__8	3.32771891177848e-17	DOWN	-8.43459571501909	7.48836387452905e-17	Amphetamine addiction: DRD1
hsa04310__14	3.94130246476423e-17	DOWN	-8.41478210036963	8.85850159245453e-17	Wnt signaling pathway: PRKCA
hsa04530__6 11 45	4.28864639350914e-17	DOWN	-8.4048752930449	9.62767810442494e-17	Tight junction: CLDN24 TJP1 TJP2
hsa05161__57	4.35496728593297e-17	UP	8.40307405534949	9.76489681416235e-17	Hepatitis B: STAT3*
hsa04020__22	4.81135651239473e-17	DOWN	-8.39136601032936	1.07753741201307e-16	Calcium signaling pathway: C00575
hsa04014__63	5.38315217931685e-17	UP	8.37815693389638	1.20415987439719e-16	Ras signaling pathway: TIAM1*
hsa04152__38	5.66471360081449e-17	UP	8.37215280824503	1.26563577359458e-16	AMPK signaling pathway: PFKL
hsa04670__14	6.51609043231687e-17	UP	8.35564146270381	1.45412516892202e-16	Leukocyte transendothelial migration: SIPA1
hsa05152__13	6.66694015462884e-17	DOWN	-8.3529396061607	1.48602379010054e-16	Tuberculosis: LAMP1
hsa04917__44	7.34274844098934e-17	UP	8.34153176742314	1.63471852140035e-16	Prolactin signaling pathway: PRLR**
hsa04910__9	7.98413951699291e-17	UP	8.33162496009841	1.77540806537629e-16	Insulin signaling pathway: ELK1
hsa05164__70	8.08602302732523e-17	UP	8.33012392868557	1.79381785930863e-16	Influenza A: RNASEL
hsa05168__83	8.08602302732523e-17	UP	8.33012392868557	1.79381785930863e-16	Herpes simplex infection: RNASEL
hsa04650__116	8.90339273290832e-17	UP	8.318716089948	1.97281544164325e-16	Natural killer cell mediated cytotoxicity: FCGR3A
hsa04110__96 97	1.16097377590294e-16	DOWN	-8.2871944302784	2.56945786209851e-16	Cell cycle: TFDP1 E2F4
hsa04924__30	1.16390663285664e-16	UP	8.28689422399583	2.57291830957367e-16	Renin secretion: PDE3A
hsa05213__12	1.19967588479992e-16	UP	8.28329174860502	2.64887307583907e-16	Endometrial cancer: BAD
hsa05161__30	1.41310241315348e-16	DOWN	-8.26377834023813	3.11645473511195e-16	Hepatitis B: MYC
hsa04970__12	1.62235506076779e-16	UP	8.24726699469691	3.57374579036656e-16	Salivary secretion: BEST2
hsa04024__77	1.86736830565607e-16	UP	8.23045544287313	4.10864759523156e-16	cAMP signaling pathway: RHOA*
hsa04972__18	2.32736514548758e-16	DOWN	-8.20403729000718	5.11475919107738e-16	Pancreatic secretion: PRKCA
hsa04724__36	2.59111273458361e-16	DOWN	-8.19112841985677	5.68773461247968e-16	Glutamatergic synapse: TRPC1
hsa04211__51	3.3155340542218e-16	UP	8.16140799788258	7.2694148049974e-16	Longevity regulating pathway - mammal: NFKB1
hsa05205__158	3.33205811706584e-16	DOWN	-8.16080758531745	7.29712960602182e-16	Proteoglycans in cancer: PDCD4
hsa04950__13	3.43292071745821e-16	UP	8.15720510992663	7.50926429348542e-16	Maturity onset diabetes of the young: INS
hsa04024__91	3.62571125778245e-16	DOWN	-8.15060057171015	7.9125568564149e-16	cAMP signaling pathway: GRIA1
hsa05211__21	3.62571125778245e-16	UP	8.15060057171015	7.9125568564149e-16	Renal cell carcinoma: TGFB1*
hsa05152__20	3.73529707026921e-16	UP	8.14699809631934	8.14225428658451e-16	Tuberculosis: FCGR1A
hsa04370__16	4.42104172855265e-16	UP	8.12658406910474	9.62588343910826e-16	VEGF signaling pathway: HSPB1
hsa04920__1	4.43199940480027e-16	UP	8.12628386282217	9.63857277965243e-16	Adipocytokine signaling pathway: C00195
hsa04015__17	4.79713404146212e-16	DOWN	-8.11667726178001	1.042059521839e-15	Rap1 signaling pathway: ACTB
hsa04071__11	6.27768494925098e-16	DOWN	-8.08395477698014	1.36209815469314e-15	Sphingolipid signaling pathway: PRKCA
hsa04925__5	7.1170476066256e-16	DOWN	-8.0686442565692	1.54243742247399e-15	Aldosterone synthesis and secretion: KCNK3
hsa04520__18	8.22667009629164e-16	DOWN	-8.05093208589771	1.78086556577558e-15	Adherens junction: SNAI2
hsa04933__56	8.87630316925909e-16	DOWN	-8.04162569113811	1.91928350460735e-15	AGE-RAGE signaling pathway in diabetic complications: NFATC1
hsa03320__64	9.71807590178353e-16	DOWN	-8.03051805868311	2.09888099074152e-15	PPAR signaling pathway: APOA5
hsa05161__45	9.95877355252606e-16	UP	8.02751599585743	2.14839672849558e-15	Hepatitis B: PCNA
hsa04152__58	9.98316391991496e-16	UP	8.02721578957487	2.15118864742204e-15	AMPK signaling pathway: SCD
hsa04152__57	1.05865122310383e-15	UP	8.02001083879324	2.27858608042623e-15	AMPK signaling pathway: ACACA*
hsa04917__56	1.20784784491328e-15	DOWN	-8.00379969953459	2.59673466886963e-15	Prolactin signaling pathway: LHCGR
hsa04621__30 32	1.21968921855859e-15	DOWN	-8.00259887440432	2.61919547619611e-15	NOD-like receptor signaling pathway: PYCARD CASP1
hsa04064__55	1.23766600317188e-15	DOWN	-8.00079763670892	2.654765319589e-15	NF-kappa B signaling pathway: CXCL12
hsa04310__36	1.28063305207206e-15	DOWN	-7.99659474875297	2.74379647074504e-15	Wnt signaling pathway: MYC
hsa05168__27	1.52962300077499e-15	UP	7.97467969012554	3.27353259505263e-15	Herpes simplex infection: IRF3
hsa04210__105	1.59800631068979e-15	DOWN	-7.96927597703932	3.41598846164517e-15	Apoptosis: ACTB
hsa04922__24	1.62931012253613e-15	UP	7.96687432677878	3.47894740936976e-15	Glucagon signaling pathway: PFKL
hsa05211__22	1.66131363031495e-15	DOWN	-7.96447267651824	3.54325574501905e-15	Renal cell carcinoma: TGFA
hsa04971__56	1.69800290464915e-15	DOWN	-7.96177081997513	3.61740074584552e-15	Gastric acid secretion: CAMK2A
hsa05205__146	1.71872946939915e-15	UP	7.96026978856229	3.65740959569764e-15	Proteoglycans in cancer: PTK2
hsa05031__96	1.76520901655326e-15	DOWN	-7.95696751945405	3.75206758156514e-15	Amphetamine addiction: PDYN
hsa05130__28	1.82173731397653e-15	DOWN	-7.95306483778067	3.86784679430724e-15	Pathogenic Escherichia coli infection: ROCK1
hsa04622__9 35	2.00708961675147e-15	UP	7.94105658647797	4.25657041746729e-15	RIG-I-like receptor signaling pathway: IRF3 PIN1
hsa04910__14	2.08632464367983e-15	DOWN	-7.93625328595689	4.41962120121128e-15	Insulin signaling pathway: C00369
hsa04024__114	2.29259523167105e-15	DOWN	-7.92454524093675	4.85111085620484e-15	cAMP signaling pathway: HHIP
hsa05166__33	2.29815376236166e-15	DOWN	-7.54808656259699	4.85740260908613e-15	HTLV-I infection: HLA-A
hsa04810__8 79	2.91073380151257e-15	UP	7.89482481896256	6.13834883618644e-15	Regulation of actin cytoskeleton: ARPC5 ACTB
hsa04810__8 82	2.91073380151257e-15	UP	7.89482481896256	6.13834883618644e-15	Regulation of actin cytoskeleton: ARPC5 ACTB*
hsa04020__7	3.00322807455228e-15	DOWN	-7.89092213728918	6.32630667273961e-15	Calcium signaling pathway: ADCY1
hsa04360__35	3.06895180949402e-15	DOWN	-7.88822028074607	6.4575145017237e-15	Axon guidance: ROCK1*
hsa04211__29	3.12856052336021e-15	DOWN	-7.88581863048553	6.57557631252107e-15	Longevity regulating pathway - mammal: EIF4E
hsa04610__52	3.21238772413635e-15	UP	7.88251636137729	6.74421959067286e-15	Complement and coagulation cascades: CPB2
hsa04520__43	3.7638325425729e-15	DOWN	-7.86270274672783	7.89312650390009e-15	Adherens junction: ACTB
hsa04931__47	4.19222670557333e-15	DOWN	-7.84919346401228	8.78171012237712e-15	Insulin resistance: AKT2*
hsa04213__2	4.22243472712292e-15	DOWN	-7.84829284516458	8.83513903370152e-15	Longevity regulating pathway - multiple species: RPS6KB1
hsa04530__22 33	4.48264472389409e-15	UP	7.84078768810039	9.3691762360367e-15	Tight junction: MYL12B CGN
hsa05205__45 46	4.61309097938836e-15	UP	7.83718521270958	9.63110883363415e-15	Proteoglycans in cancer: PAK1 FLNA
hsa05205__233 234	5.08761144255521e-15	DOWN	-7.82487675512431	1.06100132081701e-14	Proteoglycans in cancer: ITGA2 C00925
hsa04530__7 52	5.33620878797242e-15	UP	7.81887262947296	1.11161156458982e-14	Tight junction: PARD6A MPP5
hsa04261__15 16	5.58343498288046e-15	DOWN	-7.81316871010417	1.16182440009218e-14	Adrenergic signaling in cardiomyocytes: ACTC1 TPM1
hsa04014__41	6.42523598534053e-15	DOWN	-7.79545653943268	1.33551088677598e-14	Ras signaling pathway: RAC1*
hsa04510__20 69	6.44053010938889e-15	UP	7.79515633315012	1.33721061608196e-14	Focal adhesion: VASP ACTB
hsa05221__26	7.84309312303222e-15	UP	7.77023921169701	1.62661942363991e-14	Acute myeloid leukemia: BAD
hsa04024__116	9.14768661888495e-15	DOWN	-7.75072580333011	1.89509406360362e-14	cAMP signaling pathway: ACOX1
hsa05220__4	9.59046612088728e-15	DOWN	-7.74472167767876	1.98463500453163e-14	Chronic myeloid leukemia: PTPN11
hsa05164__41 42	1.17196210805062e-14	UP	7.71920414366052	2.42257073820366e-14	Influenza A: STAT1 IRF9
hsa05213__11	1.21123506847791e-14	DOWN	-7.71500125570457	2.50100076227472e-14	Endometrial cancer: FOXO3
hsa04668__48	1.27858415209467e-14	UP	7.70809651120552	2.63716753214696e-14	TNF signaling pathway: CASP3
hsa05162__81	1.31208406698138e-14	DOWN	-7.70479424209727	2.70329601080923e-14	Measles: TNFRSF10D
hsa04012__31	1.38169555764175e-14	UP	7.69818970388078	2.84359907207979e-14	ErbB signaling pathway: BAD
hsa05221__6	1.5683375597177e-14	DOWN	-7.68197856462213	3.22418629618114e-14	Acute myeloid leukemia: CEBPA
hsa04650__40	1.68646933950143e-14	DOWN	-7.67267216986254	3.46325233762098e-14	Natural killer cell mediated cytotoxicity: TNFRSF10D
hsa04360__114	1.82610997074308e-14	UP	7.66246515625524	3.74591772382777e-14	Axon guidance: RAF1
hsa04723__7	1.90013502038349e-14	DOWN	-7.65736164945159	3.8935154888774e-14	Retrograde endocannabinoid signaling: ITPR1
hsa04970__45	1.90457495286982e-14	DOWN	-7.65706144316902	3.89836202226839e-14	Salivary secretion: KCNMA1
hsa04933__12	2.03328419404133e-14	DOWN	-7.64865566725713	4.15728074059157e-14	AGE-RAGE signaling pathway in diabetic complications: EGR1
hsa04066__51	2.17053451391241e-14	DOWN	-7.64024989134524	4.43308081700153e-14	HIF-1 signaling pathway: TFRC
hsa04668__116	2.42732720005162e-14	UP	7.625839989782	4.95216917361237e-14	TNF signaling pathway: PGAM5
hsa05218__14	2.6148899978282e-14	UP	7.61623338873983	5.32904371574749e-14	Melanoma: BAD
hsa05168__106 134	2.65778154109729e-14	UP	7.61413194476186	5.41058669092288e-14	Herpes simplex infection: SRSF8 C1QBP
hsa05205__451	2.72658446678039e-14	DOWN	-7.61082967565362	5.54464525225146e-14	Proteoglycans in cancer: KDR**
hsa05132__20	2.77772034308577e-14	UP	7.60842802539307	5.64252597260341e-14	Salmonella infection: ACTB
hsa05217__19	2.82979918417168e-14	DOWN	-7.60602637513253	5.74210871172634e-14	Basal cell carcinoma: HHIP
hsa05100__24	2.88953629972836e-14	DOWN	-7.60332451858943	5.85699968413116e-14	Bacterial invasion of epithelial cells: ACTB
hsa05205__236	2.98493438193803e-14	UP	7.59912163063348	6.04384881860082e-14	Proteoglycans in cancer: ITGAV
hsa04920__31	4.34129725470682e-14	UP	7.55048821285753	8.78072932356741e-14	Adipocytokine signaling pathway: AGRP
hsa04015__18	4.49398678291032e-14	DOWN	-7.54598511861901	9.07978619901989e-14	Rap1 signaling pathway: CDH1
hsa04970__28	4.64121607321031e-14	DOWN	-7.54178223066307	9.36718045280577e-14	Salivary secretion: AQP5
hsa04550__47	6.67041836718544e-14	DOWN	-7.49434963801739	1.34481932531561e-13	Signaling pathways regulating pluripotency of stem cells: CTNNB1*
hsa05164__53	6.80920888723673e-14	DOWN	-7.49164778147428	1.37132942112731e-13	Influenza A: MAPK14
hsa04621__34 35	7.49535383621178e-14	UP	7.47903911760644	1.50789827176038e-13	NOD-like receptor signaling pathway: CASP1 PYCARD
hsa04917__47	9.47889710322792e-14	UP	7.44811787050198	1.90490349272356e-13	Prolactin signaling pathway: INS
hsa05200__222	9.5004847391983e-14	UP	7.44781766421941	1.90720201121299e-13	Pathways in cancer: CASP9*
hsa04350__41	1.06679374117245e-13	DOWN	-7.43250714380846	2.13928008501925e-13	TGF-beta signaling pathway: SMAD4***
hsa04666__20	1.11886426723548e-13	DOWN	-7.42620281187455	2.24130699161564e-13	Fc gamma R-mediated phagocytosis: PLA2G4B
hsa05014__54	1.12650396502685e-13	DOWN	-7.42530219302684	2.25420761478749e-13	Amyotrophic lateral sclerosis (ALS): PPP3CA
hsa05032__4	1.17077380340976e-13	DOWN	-7.42019868622319	2.34030210277334e-13	Morphine addiction: ADCY1
hsa04012__3	1.24180740443065e-13	UP	7.41239332287644	2.47965580544654e-13	ErbB signaling pathway: ELK1
hsa04071__57	1.40314121364475e-13	UP	7.39618218361779	2.79883475630413e-13	Sphingolipid signaling pathway: BAX
hsa04370__38	1.44822493008084e-13	UP	7.39197929566184	2.88569951603595e-13	VEGF signaling pathway: BAD
hsa05215__12	1.47462297681992e-13	DOWN	-7.3895776454013	2.93518704814051e-13	Prostate cancer: KLK3
hsa04740__10	1.48464365975557e-13	DOWN	-7.3886770265536	2.95200575310129e-13	Olfactory transduction: ANO2
hsa04010__15	1.71895236847465e-13	DOWN	-7.3691636181867	3.41428276994067e-13	MAPK signaling pathway: NFKB1
hsa05031__11	1.74625577616577e-13	UP	7.36706217420873	3.46119683904586e-13	Amphetamine addiction: GRIN3A
hsa05031__54	1.74625577616577e-13	UP	7.36706217420873	3.46119683904586e-13	Amphetamine addiction: GRIN3A*
hsa04530__30	1.78198699289012e-13	UP	7.36436031766562	3.52829669087517e-13	Tight junction: AKT3
hsa04724__5 71	1.78600119645203e-13	UP	7.36406011138305	3.53252236645618e-13	Glutamatergic synapse: GRIN3A DLG4
hsa04064__137	2.13284931838171e-13	UP	7.34034381506021	4.21411553022002e-13	NF-kappa B signaling pathway: ICAM1
hsa04662__16	2.38572223009176e-13	UP	7.32533350093183	4.70879419153615e-13	B cell receptor signaling pathway: VAV3
hsa04724__26	2.51734281597628e-13	DOWN	-7.31812855015021	4.96336532132153e-13	Glutamatergic synapse: PRKACA
hsa04115__40	2.75888543518449e-13	DOWN	-7.30582009256494	5.4339053802009e-13	p53 signaling pathway: PIDD1
hsa04917__68	2.95649284324507e-13	UP	7.29651369780535	5.81701576173559e-13	Prolactin signaling pathway: CCND1
hsa04015__14	2.98298229796504e-13	DOWN	-7.29531287267508	5.86299554171162e-13	Rap1 signaling pathway: MAPK14
hsa04360__11	3.3943157200436e-13	DOWN	-7.27790090828615	6.66449241166345e-13	Axon guidance: NFATC2
hsa05215__22	3.64436486084262e-13	DOWN	-7.26739368839629	7.14797659031658e-13	Prostate cancer: C16038
hsa04720__32	3.75137209492284e-13	DOWN	-7.26439162557061	7.35018578348281e-13	Long-term potentiation: ITPR1
hsa04910__39	3.85265773135722e-13	UP	7.2607891501798	7.54077487210439e-13	Insulin signaling pathway: BAD
hsa04310__16	3.89564832963418e-13	DOWN	-7.25928811876696	7.61698565180295e-13	Wnt signaling pathway: CAMK2A
hsa04931__104	4.69245881976577e-13	DOWN	-7.23407079103129	9.16541592758824e-13	Insulin resistance: C00369*
hsa04210__60	4.89377172768983e-13	UP	7.2283668716625	9.54869893699812e-13	Apoptosis: BBC3
hsa04668__102	5.19450802235167e-13	UP	7.22026130203318	1.01249798485465e-12	TNF signaling pathway: AKT3
hsa04911__31	5.29872964567894e-13	DOWN	-7.21755944549007	1.03174228023116e-12	Insulin secretion: CAMK2A
hsa04066__63	5.99491438317251e-13	DOWN	-7.20074789366628	1.16488563867437e-12	HIF-1 signaling pathway: TIMP1*
hsa04066__57	5.99491438317251e-13	DOWN	-7.20074789366628	1.16488563867437e-12	HIF-1 signaling pathway: TIMP1
hsa04390__89	6.37592744401003e-13	DOWN	-7.19234211775439	1.23764128794368e-12	Hippo signaling pathway: ID2
hsa04066__59	6.63331385137978e-13	DOWN	-7.18693840466817	1.28627417200646e-12	HIF-1 signaling pathway: NOS2
hsa04918__14	9.96785755392363e-13	DOWN	-7.1311000361106	1.9308870457549e-12	Thyroid hormone synthesis: DUOX2
hsa04015__96	1.0947176082295e-12	DOWN	-7.1181911659602	2.11840822436996e-12	Rap1 signaling pathway: PLCE1
hsa04919__91	1.21785289980689e-12	DOWN	-7.10348105811438	2.35426501927691e-12	Thyroid hormone signaling pathway: PFKP
hsa04012__65	1.34576526946257e-12	DOWN	-7.08967156911627	2.59886222129514e-12	ErbB signaling pathway: MYC
hsa04920__37	1.45183461847492e-12	DOWN	-7.07916434922641	2.80081852989156e-12	Adipocytokine signaling pathway: IRS1
hsa04913__36	1.47401215016033e-12	DOWN	-7.07706290524844	2.83777544072876e-12	Ovarian steroidogenesis: CYP19A1
hsa04913__37	1.47401215016033e-12	DOWN	-7.07706290524844	2.83777544072876e-12	Ovarian steroidogenesis: CYP19A1*
hsa04350__34	1.51608425720733e-12	DOWN	-7.07316022357506	2.91578538310395e-12	TGF-beta signaling pathway: ROCK1
hsa04610__46	1.66741166615879e-12	UP	7.05995114714208	3.20354449970589e-12	Complement and coagulation cascades: C2
hsa04725__53	1.71857731361954e-12	DOWN	-7.05574825918614	3.2984747418704e-12	Cholinergic synapse: CHRNA7
hsa05211__2	1.82170528996895e-12	UP	7.04764268955681	3.49284106107311e-12	Renal cell carcinoma: TGFB1
hsa04022__63	2.06414233264588e-12	DOWN	-7.03023072516789	3.9536426534573e-12	cGMP-PKG signaling pathway: C00575
hsa04072__57	2.46169143082354e-12	DOWN	-7.00561380999735	4.71030366447804e-12	Phospholipase D signaling pathway: C06124
hsa04664__3 4 5	2.58054000228187e-12	DOWN	-6.99900927178086	4.93269040110645e-12	Fc epsilon RI signaling pathway: FCER1G MS4A2 FCER1A
hsa05145__67	2.6819704260181e-12	UP	6.99360555869464	5.12136425862602e-12	Toxoplasmosis: BAD
hsa04360__21	2.70503345236505e-12	UP	6.99240473356437	5.16016026090754e-12	Axon guidance: PAK4
hsa04151__32	2.71082953134407e-12	UP	6.99210452728181	5.16597230161817e-12	PI3K-Akt signaling pathway: BCL2L1
hsa04115__55	2.82329784694128e-12	UP	6.98640060791302	5.37484970050928e-12	p53 signaling pathway: SHISA5
hsa05200__196	2.90287337469589e-12	UP	6.98249792623964	5.52074804762508e-12	Pathways in cancer: TRAF1
hsa04024__112	2.94033839558648e-12	DOWN	-6.98069668854424	5.5863456474287e-12	cAMP signaling pathway: GLI1
hsa04151__103	2.95924830744859e-12	DOWN	-6.97979606969654	5.61659350474333e-12	PI3K-Akt signaling pathway: BCL2*
hsa05152__126	2.97192111560132e-12	UP	6.9791956571314	5.63495436550442e-12	Tuberculosis: NOS2
hsa04610__23	3.02961044758822e-12	UP	6.97649380058829	5.73854640223615e-12	Complement and coagulation cascades: BDKRB1
hsa04666__40	3.38506864973433e-12	DOWN	-6.96088307389478	6.40538166450233e-12	Fc gamma R-mediated phagocytosis: PLA2G6
hsa04340__31	3.48013764545707e-12	DOWN	-6.9569803922214	6.57865053904812e-12	Hedgehog signaling pathway: GLI1***
hsa05030__80 81	3.63926828010342e-12	DOWN	-6.95067606028748	6.87254783750183e-12	Cocaine addiction: GRIN3A DLG4
hsa04724__13	3.89551435095918e-12	UP	6.94106945924532	7.34906773639788e-12	Glutamatergic synapse: GRM5
hsa04972__23	4.030265503538e-12	DOWN	-6.93626615872423	7.59565584869399e-12	Pancreatic secretion: KCNMA1
hsa05219__19	4.21401080411411e-12	DOWN	-6.92996182679031	7.93399428950943e-12	Bladder cancer: TP53
hsa05211__49	4.28614820731826e-12	DOWN	-6.92756017652977	8.06173421576677e-12	Renal cell carcinoma: TGFA*
hsa05217__3	4.87746695462914e-12	DOWN	-6.90924759329315	9.16476040774815e-12	Basal cell carcinoma: GLI1
hsa04913__64	4.90852491863725e-12	DOWN	-6.90834697444545	9.21390441770169e-12	Ovarian steroidogenesis: PLA2G4B
hsa05169__103	5.0028665598164e-12	UP	6.90564511790234	9.3816230198553e-12	Epstein-Barr virus infection: NFKB1*
hsa05150__69	5.88611030701069e-12	UP	6.88252923414464	1.1026920505357e-11	Staphylococcus aureus infection: FPR2
hsa04925__34	5.92345108727425e-12	DOWN	-6.88162861529693	1.10858213077573e-11	Aldosterone synthesis and secretion: STAR
hsa04650__36	7.11328737986978e-12	UP	6.85551066871355	1.32993701360948e-11	Natural killer cell mediated cytotoxicity: CASP3
hsa04919__87	8.50075946559404e-12	UP	6.82999313469531	1.58776610694346e-11	Thyroid hormone signaling pathway: BAD
hsa04930__15	8.73512222525757e-12	UP	6.82609045302193	1.62992002594429e-11	Type II diabetes mellitus: C00031*
hsa04915__58	1.06953334798075e-11	UP	6.79697044361287	1.99370353259507e-11	Estrogen signaling pathway: CREB3***
hsa05205__69	1.11269084966469e-11	UP	6.79126652424409	2.07209723143701e-11	Proteoglycans in cancer: MAPK1*
hsa04380__72	1.28691650664141e-11	DOWN	-6.77025208446435	2.39417437225665e-11	Osteoclast differentiation: MAPK1
hsa04210__85	1.3138934283766e-11	DOWN	-6.76725002163868	2.44194436391655e-11	Apoptosis: FASLG*
hsa04390__59	1.36385453722969e-11	DOWN	-6.76184630855246	2.53229513384841e-11	Hippo signaling pathway: SERPINE1
hsa05205__319	1.42744977497019e-11	DOWN	-6.75524177033598	2.64775728249654e-11	Proteoglycans in cancer: KDR
hsa04310__13	1.49394649929357e-11	DOWN	-6.74863723211949	2.76836831575208e-11	Wnt signaling pathway: NFATC1
hsa05200__76	1.5764515098709e-11	UP	6.74083186877273	2.91837673600731e-11	Pathways in cancer: RAC1
hsa04022__59	1.87468145244528e-11	DOWN	-6.71561454103705	3.46705359167784e-11	cGMP-PKG signaling pathway: NPPB
hsa05110__52	1.89407828458783e-11	DOWN	-6.71411350962422	3.4994819043663e-11	Vibrio cholerae infection: ADCY3
hsa04725__54	1.90581056396573e-11	DOWN	-6.71321289077651	3.51769945942202e-11	Cholinergic synapse: CHRM1*
hsa05205__22	2.09057313803151e-11	DOWN	-6.69970360806097	3.85494300918666e-11	Proteoglycans in cancer: PPP1R12A
hsa04530__1 5	2.23710028591662e-11	DOWN	-6.68979680073624	4.12108964435032e-11	Tight junction: IGSF5 IGSF5
hsa05205__400	2.30225805249491e-11	DOWN	-6.68559391278029	4.23696658240738e-11	Proteoglycans in cancer: ITGA2*
hsa05152__82	2.40842121929563e-11	DOWN	-6.67898937456381	4.4280073102314e-11	Tuberculosis: IL6
hsa04520__69	2.51937167212659e-11	DOWN	-6.67238483634732	4.62746761674083e-11	Adherens junction: IQGAP1**
hsa05166__136 139	2.68424566308588e-11	UP	6.66307844158772	4.92548593841638e-11	HTLV-I infection: TP53 TBPL2
hsa05160__58	2.80761354336056e-11	DOWN	-6.65647390337124	5.14683497363366e-11	Hepatitis C: EIF3E
hsa04115__2	3.26469548618708e-11	DOWN	-6.63425863846124	5.97891112918668e-11	p53 signaling pathway: IGFBP3
hsa05166__99	3.37957071205452e-11	DOWN	-6.62915513165759	6.18326520735193e-11	HTLV-I infection: JUN
hsa04621__4 7 8	4.66439646906093e-11	UP	6.58142233272934	8.52568187292362e-11	NOD-like receptor signaling pathway: IKBKG CHUK IKBKB
hsa05140__21	4.83699846747887e-11	DOWN	-6.57601861964312	8.83257543284043e-11	Leishmaniasis: NFKB1
hsa05160__85	5.30697982105992e-11	UP	6.56220913064501	9.67271654211993e-11	Hepatitis C: BAD
hsa05032__31	5.31767758808403e-11	DOWN	-6.56190892436245	9.67271654211993e-11	Morphine addiction: GABRR3
hsa05032__33	5.31767758808403e-11	DOWN	-6.56190892436245	9.67271654211993e-11	Morphine addiction: GABRR3*
hsa05032__55	5.31767758808403e-11	DOWN	-6.56190892436245	9.67271654211993e-11	Morphine addiction: GABRR3**
hsa04976__38	5.52498826265751e-11	DOWN	-6.55620500499366	1.00400898892973e-10	Bile secretion: ABCC2
hsa05152__23	5.59208412322832e-11	UP	6.55440376729826	1.01521990990783e-10	Tuberculosis: PPP3CA
hsa05219__27	6.48805147298531e-11	DOWN	-6.53218850238825	1.17674215422195e-10	Bladder cancer: RPS6KA5
hsa05205__189	6.59293925965737e-11	UP	6.52978685212771	1.19461261995142e-10	Proteoglycans in cancer: IL12B
hsa04610__7	7.72190823743131e-11	DOWN	-6.50607055580487	1.39782905377008e-10	Complement and coagulation cascades: C00290
hsa05223__14	8.26408299724477e-11	UP	6.49586354219757	1.49453435532463e-10	Non-small cell lung cancer: CCND1
hsa05200__214	8.89640741209965e-11	UP	6.48475590974257	1.60734130070531e-10	Pathways in cancer: CSF3R
hsa04115__19	9.11146600874154e-11	UP	6.48115343435176	1.64303691270877e-10	p53 signaling pathway: RFWD2
hsa05223__21	9.11146600874154e-11	DOWN	-6.48115343435176	1.64303691270877e-10	Non-small cell lung cancer: FOXO3*
hsa04015__95	1.01639683672641e-10	UP	6.46464208881055	1.83107349588583e-10	Rap1 signaling pathway: THBS1
hsa05212__31	1.03266417276397e-10	UP	6.46224043855	1.85859768258957e-10	Pancreatic cancer: RAC1*
hsa04912__15	1.10468618917263e-10	DOWN	-6.45203342494271	1.98632090856973e-10	GnRH signaling pathway: CAMK2A
hsa05152__15	1.16305294719933e-10	DOWN	-6.44422806159595	2.08927006480644e-10	Tuberculosis: CTSD
hsa04924__58	1.20999143085638e-10	DOWN	-6.4382239359446	2.16944074291903e-10	Renin secretion: PPP3CA
hsa05031__59	1.20999143085638e-10	DOWN	-6.4382239359446	2.16944074291903e-10	Amphetamine addiction: PPP3CA
hsa05168__10	1.21959888161385e-10	DOWN	-6.43702311081433	2.18458179080308e-10	Herpes simplex infection: FOS
hsa04725__64	1.22928088146319e-10	UP	6.43582228568406	2.1998274059708e-10	Cholinergic synapse: KCNJ3
hsa04115__30	1.36219341697586e-10	UP	6.42021155899054	2.43304318488369e-10	p53 signaling pathway: SERPINE1
hsa04810__23	1.36219341697586e-10	DOWN	-6.42021155899054	2.43304318488369e-10	Regulation of actin cytoskeleton: GSN
hsa04550__9	1.38385064919361e-10	UP	6.41780990873	2.46937831893144e-10	Signaling pathways regulating pluripotency of stem cells: HNF1A
hsa04917__45	1.4366441293547e-10	UP	6.41210598936122	2.56115210536764e-10	Prolactin signaling pathway: SLC2A2
hsa05215__34	1.58515797973385e-10	UP	6.39709567523284	2.82323397527953e-10	Prostate cancer: BAD
hsa04064__96	1.60080937715107e-10	UP	6.39559464382	2.84840986710876e-10	NF-kappa B signaling pathway: BCL2A1
hsa05231__21	1.69793836781349e-10	DOWN	-6.38658845534297	3.01837861222474e-10	Choline metabolism in cancer: PCYT1A
hsa05162__27 28	1.75895511953296e-10	UP	6.38118474225675	3.12389099206279e-10	Measles: STAT1 IRF9
hsa04015__30	1.80081772111165e-10	DOWN	-6.37758226686594	3.1952186005371e-10	Rap1 signaling pathway: ITGAL
hsa04550__101	2.01333333830921e-10	DOWN	-6.36047050875959	3.56891824781416e-10	Signaling pathways regulating pluripotency of stem cells: ESRRB
hsa04933__30	2.03707969067995e-10	UP	6.35866927106419	3.60760861337193e-10	AGE-RAGE signaling pathway in diabetic complications: CXCL8
hsa04064__52	2.05306236731106e-10	UP	6.35746844593391	3.63248981937616e-10	NF-kappa B signaling pathway: TRAF1
hsa05032__13	2.23280233099597e-10	DOWN	-6.34455957578351	3.94678793973793e-10	Morphine addiction: PRKACA
hsa04540__11	2.34427473408619e-10	DOWN	-6.33705441871932	4.13993630201876e-10	Gap junction: C00780
hsa04932__56	2.34884488998499e-10	UP	6.33675421243675	4.14411225190779e-10	Non-alcoholic fatty liver disease (NAFLD): CASP7
hsa05215__14	2.35342374791238e-10	DOWN	-6.33645400615418	4.148295705748e-10	Prostate cancer: CCND1
hsa04950__7	2.49491712314711e-10	UP	6.32744781767716	4.39357945116535e-10	Maturity onset diabetes of the young: FOXA3
hsa04261__62	2.55878042468174e-10	DOWN	-6.32354513600378	4.50182436140168e-10	Adrenergic signaling in cardiomyocytes: BCL2
hsa05110__14	2.61406335377237e-10	DOWN	-6.32024286689553	4.58620452076404e-10	Vibrio cholerae infection: C00238*
hsa05110__15	2.61406335377237e-10	DOWN	-6.32024286689553	4.58620452076404e-10	Vibrio cholerae infection: C01330
hsa05110__16	2.61406335377237e-10	DOWN	-6.32024286689553	4.58620452076404e-10	Vibrio cholerae infection: C00698
hsa04510__24 69	2.80326878565815e-10	DOWN	-6.3094354407231	4.91356534351834e-10	Focal adhesion: ZYX ACTB
hsa05200__188	2.95388550557821e-10	DOWN	-6.30132987109377	5.17274078749437e-10	Pathways in cancer: KLK3
hsa04151__101	2.97686082852573e-10	UP	6.3001290459635	5.20812057430154e-10	PI3K-Akt signaling pathway: PKN3
hsa04210__59	3.01748824190954e-10	UP	6.29802760198553	5.27428875027723e-10	Apoptosis: PMAIP1
hsa04071__59 60	3.03506527544883e-10	DOWN	-6.29712698313783	5.30008146149475e-10	Sphingolipid signaling pathway: TP53 BCL2
hsa04310__31	3.37560710162676e-10	DOWN	-6.28061563759661	5.88929038436089e-10	Wnt signaling pathway: MMP7
hsa04710__5	3.7245470814774e-10	UP	6.26530511718566	6.49204449545087e-10	Circadian rhythm: RORA
hsa04010__88 92	3.94600207527972e-10	DOWN	-6.25629892870864	6.87167553239165e-10	MAPK signaling pathway: ECSIT TRAF6
hsa04151__34	4.09285094065955e-10	DOWN	-6.25059500933985	7.12080270138824e-10	PI3K-Akt signaling pathway: GYS1
hsa05218__8	4.531249882463e-10	UP	6.23468407636377	7.8762428576762e-10	Melanoma: CDK4
hsa05200__53	4.69931206631792e-10	UP	6.22898015699498	8.16082012256133e-10	Pathways in cancer: BCL2L1
hsa05032__37	5.16130925147712e-10	UP	6.21427004914917	8.95484772255356e-10	Morphine addiction: KCNJ3
hsa05120__52	5.36236257884856e-10	DOWN	-6.20826592349782	9.29509159193399e-10	Epithelial cell signaling in Helicobacter pylori infection: LYN
hsa05321__95	5.45531101815095e-10	UP	6.20556406695471	9.44749253742455e-10	Inflammatory bowel disease (IBD): SMAD2
hsa04930__8	5.60303062843819e-10	UP	6.20136117899877	9.69437803944324e-10	Type II diabetes mellitus: C00022
hsa04014__104	5.66752731134498e-10	UP	6.19955994130336	9.79694923460646e-10	Ras signaling pathway: BRAP*
hsa04919__11	6.3295378585985e-10	DOWN	-6.18214797691444	1.09312515039583e-09	Thyroid hormone signaling pathway: CTNNB1
hsa04728__60	6.53747808532805e-10	UP	6.17704447011079	1.12800012142621e-09	Dopaminergic synapse: CACNA1A
hsa04152__89	7.1612358334516e-10	DOWN	-6.16263456854755	1.23449193862895e-09	AMPK signaling pathway: CFTR
hsa04913__45	7.17482933549859e-10	DOWN	-6.16233436226498	1.23570158766286e-09	Ovarian steroidogenesis: ACOT2
hsa05205__109	8.0229895889831e-10	DOWN	-6.14462219159349	1.38051258586989e-09	Proteoglycans in cancer: SMAD2
hsa05200__207	8.55537657979839e-10	DOWN	-6.13441517798619	1.47077333883268e-09	Pathways in cancer: CDK4
hsa05222__39	9.26075501053299e-10	UP	6.12180651411835	1.59058123078533e-09	Small cell lung cancer: BCL2L1
hsa04370__28	9.89162391225646e-10	DOWN	-6.11129929422849	1.69738459645022e-09	VEGF signaling pathway: SHC2
hsa04611__7	1.04655673772091e-09	DOWN	-6.10229310575146	1.79423367716933e-09	Platelet activation: ITPR1
hsa04724__52	1.1155329222955e-09	DOWN	-6.09208609214416	1.91074417592821e-09	Glutamatergic synapse: CACNA1A
hsa04014__38	1.14735439932927e-09	DOWN	-6.08758299790565	1.9634598509469e-09	Ras signaling pathway: MAPK8
hsa05166__132 136	1.18227265525904e-09	UP	6.08277969738457	2.02137426681687e-09	HTLV-I infection: CREBBP TP53
hsa04024__93	1.22967862380239e-09	UP	6.07647536545065	2.10051466738609e-09	cAMP signaling pathway: ORAI1
hsa04520__10	1.54976486996478e-09	UP	6.03924978641227	2.64487574083907e-09	Adherens junction: NLK
hsa05168__29	1.74539434733814e-09	UP	6.02003658432794	2.97603990802937e-09	Herpes simplex infection: IKBKG
hsa04151__25	1.83836395211034e-09	DOWN	-6.01163080841605	3.13171882684979e-09	PI3K-Akt signaling pathway: CDKN1B
hsa04950__18	1.89363758428108e-09	UP	6.00682750789497	3.22295744643492e-09	Maturity onset diabetes of the young: SLC2A2
hsa04917__57	2.28183269284491e-09	UP	5.97650667335564	3.88014808131727e-09	Prolactin signaling pathway: ESR1
hsa04115__56	2.44710865023722e-09	DOWN	-5.96509883461807	4.15742961464352e-09	p53 signaling pathway: SESN3
hsa04068__39	2.45612302715063e-09	UP	5.96449842205294	4.16897485818974e-09	FoxO signaling pathway: CCNB3
hsa04950__5	2.46516974304438e-09	DOWN	-5.9638980094878	4.18055410395342e-09	Maturity onset diabetes of the young: GCK
hsa04360__4	2.67751836831149e-09	DOWN	-5.95038872677226	4.53657079716617e-09	Axon guidance: GNAI1*
hsa04024__92	3.03813384105911e-09	UP	5.92967449327509	5.14293106968474e-09	cAMP signaling pathway: GRIN3A
hsa04917__34	3.38364156878676e-09	DOWN	-5.91196232260361	5.72264852182748e-09	Prolactin signaling pathway: ELF5
hsa04913__40	3.67259241111446e-09	DOWN	-5.89845303988807	6.20575642129863e-09	Ovarian steroidogenesis: HSD17B1
hsa05145__9	3.71964724378304e-09	DOWN	-5.89635159591009	6.27962009979185e-09	Toxoplasmosis: MAPK1
hsa05161__92	4.90775881953064e-09	UP	5.85042003467725	8.27798817046505e-09	Hepatitis B: NFKBIA
hsa04650__110 111	5.01518679481649e-09	UP	5.84681755928644	8.4516017824755e-09	Natural killer cell mediated cytotoxicity: ITGAL ITGB2
hsa04340__40	5.20871647906906e-09	DOWN	-5.84051322735252	8.76987299656878e-09	Hedgehog signaling pathway: SUFU
hsa04662__32 51	5.30340864792395e-09	DOWN	-5.83751116452684	8.92131141400993e-09	B cell receptor signaling pathway: BLNK GRB2
hsa05160__12 13 14	5.50774542145044e-09	UP	5.83120683259292	9.25675639258083e-09	Hepatitis C: IKBKG CHUK IKBKB
hsa05152__81	5.62792699855653e-09	UP	5.82760435720211	9.45029028622673e-09	Tuberculosis: IFNA1
hsa04115__23	5.74033198484097e-09	DOWN	-5.82430208809387	9.63043196385374e-09	p53 signaling pathway: PTEN
hsa04922__36	5.86544649262242e-09	DOWN	-5.82069961270306	9.83155571778549e-09	Glucagon signaling pathway: GYS1
hsa04914__23	6.05810613427428e-09	UP	5.81529589961684	1.01454379913559e-08	Progesterone-mediated oocyte maturation: PRKACA
hsa04210__3	6.12368342535753e-09	UP	5.81349466192144	1.02461274766223e-08	Apoptosis: BCL2L1
hsa04010__129	6.17885816800428e-09	DOWN	-5.8119936305086	1.03292477737367e-08	MAPK signaling pathway: FOS
hsa04810__21 82	6.5436010518098e-09	UP	5.80238702946644	1.09292678900894e-08	Regulation of actin cytoskeleton: CFL1 ACTB
hsa04012__21	6.89217793549539e-09	UP	5.79368104727198	1.15012454181135e-08	ErbB signaling pathway: GSK3B
hsa04068__48	7.16859658638373e-09	DOWN	-5.78707650905549	1.1951901495843e-08	FoxO signaling pathway: FASLG
hsa05223__24	7.40274928970249e-09	UP	5.78167279596927	1.2331352761836e-08	Non-small cell lung cancer: STK4
hsa04742__18	7.48244032688132e-09	DOWN	-5.77987155827387	1.24530605617449e-08	Taste transduction: PDE1A
hsa04350__21	7.57646784079497e-09	DOWN	-5.77777011429589	1.25983920998706e-08	TGF-beta signaling pathway: CDKN2B
hsa05166__34 35 36	8.52137603931385e-09	DOWN	-5.75795649964643	1.41570871599211e-08	HTLV-I infection: MYC TRRAP KAT5
hsa04211__62	8.94015031094993e-09	UP	5.74985093001711	1.48397017970626e-08	Longevity regulating pathway - mammal: EHMT2
hsa05150__48	9.08412825158004e-09	UP	5.747149073474	1.5065381275127e-08	Staphylococcus aureus infection: C3AR1
hsa05140__16	9.24674771361732e-09	DOWN	-5.74414701064832	1.53215511057204e-08	Leishmaniasis: STAT1
hsa05200__212	1.0139054478879e-08	DOWN	-5.72853628395481	1.67852716879415e-08	Pathways in cancer: CCND1***
hsa04024__43	1.05412733357749e-08	DOWN	-5.72193174573832	1.74357857376066e-08	cAMP signaling pathway: MAPK8
hsa05168__92 93	1.05599197793479e-08	UP	5.72163153945575	1.74512658446744e-08	Herpes simplex infection: IRF9 STAT1
hsa04664__23	1.07671580911188e-08	DOWN	-5.71832927034751	1.77781107673219e-08	Fc epsilon RI signaling pathway: AKT3
hsa05168__91 92	1.19269422046909e-08	UP	5.70091730595859	1.96757896423302e-08	Herpes simplex infection: STAT1 IRF9
hsa04360__31	1.3872960565222e-08	UP	5.67509956565778	2.28660464053088e-08	Axon guidance: CDC42*
hsa05210__53	1.43176616278492e-08	DOWN	-5.66969585257156	2.3578340226756e-08	Colorectal cancer: CCND1*
hsa04710__11	1.5626835752835e-08	DOWN	-5.65468553844318	2.57117551484911e-08	Circadian rhythm: CRY1
hsa04950__15	1.66406893783062e-08	UP	5.64387811227075	2.73559539298665e-08	Maturity onset diabetes of the young: IAPP
hsa04340__15	1.71413863505015e-08	DOWN	-5.6387746054671	2.81544274061122e-08	Hedgehog signaling pathway: HHIP
hsa05200__203	1.79668216399223e-08	DOWN	-5.63066903583777	2.94844173462131e-08	Pathways in cancer: TGFA*
hsa04380__32	1.87003051693623e-08	DOWN	-5.62376429133872	3.06613206049143e-08	Osteoclast differentiation: AKT3
hsa05216__15	1.9194241259169e-08	DOWN	-5.6192611971002	3.14437483225619e-08	Thyroid cancer: CCND1
hsa04932__97	1.94966586902474e-08	UP	5.6165593405571	3.19113429259363e-08	Non-alcoholic fatty liver disease (NAFLD): TNF*
hsa04520__9 57	2.45855280795615e-08	UP	5.57633169869304	4.02055763807624e-08	Adherens junction: LEF1 CTNNB1
hsa04010__78	2.46279695331275e-08	DOWN	-5.57603149241047	4.02399606545623e-08	MAPK signaling pathway: MAP3K4
hsa05200__66	2.60691244904757e-08	UP	5.56612468508574	4.2557675862384e-08	Pathways in cancer: CCND1
hsa05205__238	2.70284791773552e-08	UP	5.55982035315182	4.40855142137591e-08	Proteoglycans in cancer: ITGAV*
hsa04151__2	2.73558160205559e-08	DOWN	-5.55771890917385	4.45807270621201e-08	PI3K-Akt signaling pathway: EIF4E
hsa04115__37	2.79739558250444e-08	DOWN	-5.55381622750047	4.5548581451697e-08	p53 signaling pathway: FAS
hsa04662__35	2.90510436452533e-08	DOWN	-5.54721168928398	4.72613948133601e-08	B cell receptor signaling pathway: CD79B
hsa04621__33 35	2.98083782731661e-08	UP	5.54270859504547	4.8451507591072e-08	NOD-like receptor signaling pathway: NLRC4 PYCARD
hsa05200__225	3.12201269604168e-08	DOWN	-5.53460302541614	5.06585652492428e-08	Pathways in cancer: PPARD
hsa05221__11	3.12201269604168e-08	DOWN	-5.53460302541614	5.06585652492428e-08	Acute myeloid leukemia: PPARD
hsa04066__61	3.26407740066643e-08	DOWN	-5.52679766206939	5.29180451756015e-08	HIF-1 signaling pathway: HMOX1
hsa04621__23	3.32605170810413e-08	DOWN	-5.52349539296114	5.38763030993763e-08	NOD-like receptor signaling pathway: CASP1
hsa04115__52 53	3.54905056088052e-08	UP	5.51208755422357	5.7438983668342e-08	p53 signaling pathway: CDK4 CCND1
hsa04931__140	3.98481460864107e-08	DOWN	-5.49167352700898	6.44360296870617e-08	Insulin resistance: G00369
hsa04730__30	4.09465098406908e-08	DOWN	-5.4868702264879	6.61551951768341e-08	Long-term depression: C00025*
hsa04064__114	4.12256545785794e-08	UP	5.48566940135763	6.65489733274491e-08	NF-kappa B signaling pathway: BCL2A1*
hsa05162__28 34	4.17894903507787e-08	UP	5.48326775109708	6.74012466687666e-08	Measles: IRF9 STAT1
hsa05212__19	4.58733365320822e-08	UP	5.46675640555587	7.39245277390931e-08	Pancreatic cancer: MAPK8
hsa04340__50	4.68144503743226e-08	DOWN	-5.46315393016506	7.53764800799933e-08	Hedgehog signaling pathway: BCL2
hsa04210__4	4.76129851974227e-08	DOWN	-5.46015186733938	7.65965746455113e-08	Apoptosis: DFFA
hsa04150__31	4.77742690891373e-08	UP	5.45955145477424	7.67902922313849e-08	mTOR signaling pathway: EIF4E
hsa04350__50	4.78551095071447e-08	DOWN	-5.45925124849168	7.68544878324144e-08	TGF-beta signaling pathway: AMHR2
hsa04115__34	4.90837453948084e-08	DOWN	-5.45474815425316	7.87603395361614e-08	p53 signaling pathway: ZMAT3
hsa04010__14	5.08553268926613e-08	UP	5.44844382231924	8.15334123134049e-08	MAPK signaling pathway: MAPT
hsa05145__11	5.25114735548714e-08	DOWN	-5.44273990295046	8.41168446799687e-08	Toxoplasmosis: MAPK14
hsa04064__25	5.29559167509269e-08	UP	5.44123887153762	8.47565311541667e-08	NF-kappa B signaling pathway: NFKB2
hsa04210__31 32 33	5.41285985863928e-08	UP	5.43733618986424	8.65596908458145e-08	Apoptosis: TRAF2 RIPK1 TRADD
hsa04660__26	5.63600090228287e-08	UP	5.43013123908262	9.00514089744006e-08	T cell receptor signaling pathway: GRB2
hsa04360__117	5.89769321762245e-08	DOWN	-5.4220256694533	9.41526385379149e-08	Axon guidance: CFL1*
hsa04210__61	6.39227920725092e-08	DOWN	-5.40761576789005	1.01961737100378e-07	Apoptosis: APAF1
hsa04727__13	6.44605159898614e-08	UP	5.40611473647721	1.02732238799788e-07	GABAergic synapse: CACNA1A
hsa04151__105 62	6.63217548911656e-08	UP	5.40101122967356	1.05608963932627e-07	PI3K-Akt signaling pathway: CCND1 CDK2
hsa05161__68	6.71031869271143e-08	UP	5.39890978569559	1.0676281815076e-07	Hepatitis B: JUN
hsa05169__30	7.03190620094456e-08	DOWN	-5.3905040097837	1.11784701789973e-07	Epstein-Barr virus infection: FGR
hsa05219__12	7.35611687403453e-08	DOWN	-5.38239844015437	1.16839759985722e-07	Bladder cancer: ERBB2
hsa04390__13	7.43010713664533e-08	UP	5.38059720245897	1.17915298224295e-07	Hippo signaling pathway: BIRC5
hsa04024__25	7.70761628022796e-08	DOWN	-5.37399266424248	1.22216126502518e-07	cAMP signaling pathway: CFTR
hsa04660__30	8.08879889350608e-08	UP	5.36528668204802	1.28152218557318e-07	T cell receptor signaling pathway: CD40LG
hsa05142__53	9.85312309179426e-08	UP	5.32956213442248	1.55973195362101e-07	Chagas disease (American trypanosomiasis): AKT3
hsa04917__75	9.86942183030408e-08	UP	5.32926192813991	1.56099693763816e-07	Prolactin signaling pathway: CCND1**
hsa05222__34	1.03194853920867e-07	UP	5.32115635851058	1.63080849888401e-07	Small cell lung cancer: CCND1
hsa04650__35	1.10593193521129e-07	UP	5.30854769464275	1.74625723215295e-07	Natural killer cell mediated cytotoxicity: BID
hsa04918__10	1.22259522641742e-07	UP	5.29023511140612	1.92884670901623e-07	Thyroid hormone synthesis: TG
hsa05215__13	1.24895413998299e-07	DOWN	-5.28633242973274	1.96877921898326e-07	Prostate cancer: BCL2
hsa04261__8 38	1.30760775278536e-07	DOWN	-5.27792665382085	2.0595096123082e-07	Adrenergic signaling in cardiomyocytes: ATP2A2 PLN
hsa04210__107	1.38467895782488e-07	DOWN	-5.26741943393098	2.17907182726377e-07	Apoptosis: MCL1
hsa04740__33	1.45897767873244e-07	UP	5.25781283288882	2.29407452580606e-07	Olfactory transduction: CNGA3*
hsa04211__39	1.49268233716997e-07	UP	5.25360994493288	2.34510878891503e-07	Longevity regulating pathway - mammal: TP53*
hsa04014__69	1.52217026170951e-07	DOWN	-5.25000746954206	2.38943853112128e-07	Ras signaling pathway: PLCE1*
hsa04340__20 22	1.53462246908538e-07	DOWN	-5.24850643812923	2.40697464057715e-07	Hedgehog signaling pathway: GLI1 SUFU*
hsa05222__19	1.65659128420249e-07	UP	5.23439674284855	2.59610927691116e-07	Small cell lung cancer: CASP9
hsa04010__58	1.73084323108617e-07	UP	5.22629117321922	2.7102120260091e-07	MAPK signaling pathway: CDC25B
hsa05142__64	1.80830810675211e-07	UP	5.2181856035899	2.82915148425248e-07	Chagas disease (American trypanosomiasis): CASP8
hsa05210__31	1.97023088821668e-07	UP	5.20227467061382	3.07991999913407e-07	Colorectal cancer: BCL2
hsa04114__56	2.03162262892499e-07	DOWN	-5.19657075124503	3.17324930985043e-07	Oocyte meiosis: REC8
hsa04340__49	2.0513906920548e-07	UP	5.19476951354963	3.20146437738452e-07	Hedgehog signaling pathway: CCND1
hsa05222__35	2.09486124914671e-07	UP	5.19086683187625	3.26659276941633e-07	Small cell lung cancer: NOS2
hsa04668__47	2.12890457213067e-07	UP	5.18786476905057	3.31692511694323e-07	TNF signaling pathway: CASP7
hsa04713__14	2.16696969412036e-07	DOWN	-5.18456249994233	3.37343500849392e-07	Circadian entrainment: PRKCA
hsa04810__30	2.35599753728362e-07	DOWN	-5.16895177324881	3.66466835476483e-07	Regulation of actin cytoskeleton: VCL*
hsa04971__39	2.65693965234666e-07	UP	5.14643630205625	4.12594182376807e-07	Gastric acid secretion: EZR
hsa05166__53 146	2.65693965234666e-07	DOWN	-5.14643630205625	4.12594182376807e-07	HTLV-I infection: CREB1 CRTC2
hsa04621__29	2.68255740042409e-07	UP	5.14463506436084	4.1622835304681e-07	NOD-like receptor signaling pathway: CASP5
hsa04722__73 77	2.73014421974748e-07	DOWN	-5.1413327952526	4.23262457830488e-07	Neurotrophin signaling pathway: NGFRAP1 YWHAE
hsa04014__66	2.79635106622892e-07	UP	5.13682970101408	4.33169303663986e-07	Ras signaling pathway: RAF1*
hsa05161__125	3.23764472538035e-07	DOWN	-5.10921072301786	5.01114863178722e-07	Hepatitis B: CDKN1A
hsa05205__17	3.54401701736537e-07	DOWN	-5.09209896491151	5.48082960957164e-07	Proteoglycans in cancer: AKT3
hsa04210__56	3.6522231408556e-07	UP	5.08639504554273	5.64352572505566e-07	Apoptosis: BAX
hsa05014__31 34	3.69288674558967e-07	DOWN	-5.08429360156475	5.70167148312489e-07	Amyotrophic lateral sclerosis (ALS): NEFL PRPH
hsa04610__45	3.9399781106372e-07	UP	5.07198514397948	6.07817641205854e-07	Complement and coagulation cascades: C4A
hsa04024__62	3.95243118486216e-07	UP	5.07138473141435	6.09238572301559e-07	cAMP signaling pathway: BAD
hsa04713__56	4.02160254889856e-07	UP	5.0680824623061	6.19392720441016e-07	Circadian entrainment: KCNJ3
hsa05152__78	4.15037265834569e-07	UP	5.06207833665475	6.38701902131987e-07	Tuberculosis: IL1A
hsa04612__18	4.21624057447307e-07	UP	5.05907627382908	6.48307368202528e-07	Antigen processing and presentation: KIR2DS2
hsa04916__7	4.56099932262668e-07	DOWN	-5.0440659597007	7.00745521440354e-07	Melanogenesis: TYRP1
hsa04064__54	4.57534052960152e-07	DOWN	-5.04346554713556	7.02374579666769e-07	NF-kappa B signaling pathway: CCL13
hsa04151__97	4.78074221686558e-07	UP	5.03505977122367	7.33307316366565e-07	PI3K-Akt signaling pathway: MCL1
hsa05161__78	5.4262578785111e-07	UP	5.01074306233569	8.31642622652721e-07	Hepatitis B: TNF
hsa05169__60	5.8113309851512e-07	UP	4.99753398590272	8.89934060399276e-07	Epstein-Barr virus infection: NFKB1
hsa04064__53	5.93928494413078e-07	UP	4.99333109794677	9.08787981272128e-07	NF-kappa B signaling pathway: CXCL8
hsa04742__48	6.21302739697039e-07	DOWN	-4.98462511575231	9.49900608535994e-07	Taste transduction: GABBR1
hsa04014__64	6.38901045222413e-07	DOWN	-4.9792214026661	9.7601224713245e-07	Ras signaling pathway: PIK3R5*
hsa05223__9	6.5291977289269e-07	UP	4.97501851471015	9.96617589979988e-07	Non-small cell lung cancer: BAD
hsa04730__20	6.71379921290041e-07	DOWN	-4.96961480162393	1.02396337021428e-06	Long-term depression: C00025
hsa04024__21	6.88210334989432e-07	DOWN	-4.96481150110285	1.04878119987441e-06	cAMP signaling pathway: AKT3
hsa04014__61	7.69111118796761e-07	DOWN	-4.94319664875798	1.17111814604466e-06	Ras signaling pathway: RAP1A
hsa04520__17	8.04220081973194e-07	DOWN	-4.93449066656352	1.22311535393415e-06	Adherens junction: SNAI1
hsa04520__58	8.04561243992874e-07	UP	4.74325926456797	1.22311535393415e-06	Adherens junction: CDH1*
hsa04930__7	8.68408429859221e-07	UP	4.91948035243515	1.31911029887266e-06	Type II diabetes mellitus: C00002
hsa04360__18	8.88608217179037e-07	DOWN	-4.91497725819663	1.34870342494298e-06	Axon guidance: PTK2
hsa05164__34	9.10653145393583e-07	DOWN	-4.91017395767555	1.38104702194878e-06	Influenza A: IL1B
hsa05162__25 70	9.24697624686782e-07	DOWN	-4.90717189484987	1.40121519095683e-06	Measles: IFNAR1 GNB2L1
hsa05032__30	9.31796481867306e-07	DOWN	-4.90567086343704	1.41083447979748e-06	Morphine addiction: ADORA1
hsa04062__40	9.85995184968683e-07	DOWN	-4.89456323098204	1.49169480882138e-06	Chemokine signaling pathway: PRKACA
hsa04933__58	1.04799798243657e-06	DOWN	-4.88255497967933	1.58422221158352e-06	AGE-RAGE signaling pathway in diabetic complications: CCL2
hsa04950__11	1.05279649811261e-06	UP	4.88165436083163	1.59019663983408e-06	Maturity onset diabetes of the young: HNF4G
hsa05152__88 89	1.09029354975095e-06	UP	4.87474961633257	1.64551130922251e-06	Tuberculosis: ITGAX ITGB2
hsa04062__43	1.10195933473632e-06	DOWN	-4.8726481723546	1.66178297750365e-06	Chemokine signaling pathway: STAT1
hsa04728__64	1.10363556353489e-06	UP	4.87234796607203	1.66297612179797e-06	Dopaminergic synapse: SCN1A
hsa04666__50 52	1.11205357970518e-06	DOWN	-4.87084693465919	1.67431784957214e-06	Fc gamma R-mediated phagocytosis: DNM2 AMPH
hsa05150__14	1.30970707006644e-06	UP	4.83842465614189	1.97032793006792e-06	Staphylococcus aureus infection: FPR1
hsa04340__51	1.33365297516961e-06	DOWN	-4.83482218075108	2.00474715227496e-06	Hedgehog signaling pathway: CCND1*
hsa05221__41	1.44669840999548e-06	DOWN	-4.81861104149243	2.17293869894604e-06	Acute myeloid leukemia: MAPK1
hsa04912__26	1.4554290567038e-06	DOWN	-4.81741021636216	2.18430606832783e-06	GnRH signaling pathway: PLD1
hsa04668__128	1.54325067041508e-06	UP	4.80570217134203	2.31426018332796e-06	TNF signaling pathway: CHUK*
hsa04210__99	1.58073476667533e-06	DOWN	-4.80089887082095	2.36858104193218e-06	Apoptosis: BID**
hsa04510__20 4 5	1.7318336794641e-06	UP	4.78258628758432	2.59292070415383e-06	Focal adhesion: VASP ITGB1 ITGA11
hsa04919__30	1.76578343889851e-06	DOWN	-4.77868360591094	2.64164576567699e-06	Thyroid hormone signaling pathway: MYH6
hsa04010__118	1.83561149670303e-06	UP	4.77087824256419	2.74392522060858e-06	MAPK signaling pathway: JUN
hsa05010__50	1.85486006321687e-06	DOWN	-4.76877679858621	2.77049448234061e-06	Alzheimer's disease: ERN1
hsa04723__42	2.06750380054172e-06	DOWN	-4.74686173995878	3.08320606445865e-06	Retrograde endocannabinoid signaling: KCNJ3
hsa04723__50	2.06750380054172e-06	DOWN	-4.74686173995878	3.08320606445865e-06	Retrograde endocannabinoid signaling: KCNJ3*
hsa04360__29	2.08289506683617e-06	DOWN	-4.74536070854594	3.10369534542835e-06	Axon guidance: RASA1
hsa05161__48	2.14874857305687e-06	UP	4.73905637661202	3.19928571218213e-06	Hepatitis B: STAT1
hsa04621__42	2.32739601635034e-06	UP	4.72284523735337	3.46253136557584e-06	NOD-like receptor signaling pathway: MAPK8
hsa05160__77	2.43630775730354e-06	UP	4.71353884259378	3.62169483858651e-06	Hepatitis C: NFKB1*
hsa05200__65	2.50915222219403e-06	UP	4.70753471694242	3.72703322174117e-06	Pathways in cancer: STK4
hsa04727__8	2.64946215290515e-06	DOWN	-4.69642708448742	3.93233758713174e-06	GABAergic synapse: ADCY1
hsa05223__23	2.76466801134932e-06	UP	4.68772110229296	4.10008776110921e-06	Non-small cell lung cancer: CASP9*
hsa04015__92	2.91863506805161e-06	DOWN	-4.67661346983796	4.32501206062222e-06	Rap1 signaling pathway: C00076*
hsa04724__3	2.94437953955348e-06	DOWN	-4.67481223214256	4.35972352625768e-06	Glutamatergic synapse: GRIK1
hsa05152__77	3.40667493290845e-06	UP	4.6447916038858	5.04026944798029e-06	Tuberculosis: IL12A
hsa05161__10	3.62092704786797e-06	UP	4.63218294001796	5.35304635951527e-06	Hepatitis B: CASP3
hsa04621__28	3.68447718428568e-06	UP	4.62858046462715	5.4427143311893e-06	NOD-like receptor signaling pathway: CASP8
hsa04727__35	3.87599750477269e-06	DOWN	-4.61807324473728	5.71663996190571e-06	GABAergic synapse: PRKACA
hsa05321__138	3.87599750477269e-06	UP	4.61807324473728	5.71663996190571e-06	Inflammatory bowel disease (IBD): IFNG**
hsa04540__12	4.30661999145646e-06	UP	4.59615818610985	6.34677565799741e-06	Gap junction: C00025
hsa05164__31 32 33	4.38163735463929e-06	DOWN	-4.59255571071904	6.45227005436303e-06	Influenza A: NLRP3 PYCARD CASP1
hsa04810__26 80	4.54855826027899e-06	UP	4.58475034737228	6.69282769856243e-06	Regulation of actin cytoskeleton: PFN3 ACTB
hsa04930__13	4.61435874343425e-06	UP	4.5817482845466	6.78433496002579e-06	Type II diabetes mellitus: C00162
hsa04210__106	4.69452327772964e-06	DOWN	-4.57814580915579	6.89680159410008e-06	Apoptosis: TUBA1B
hsa04970__39	4.70125465393733e-06	DOWN	-4.57784560287322	6.90129491777206e-06	Salivary secretion: KCNN4
hsa05231__18	4.70801306916515e-06	DOWN	-4.57754539659066	6.90582088755763e-06	Choline metabolism in cancer: CHKA
hsa04620__12	4.75552034018826e-06	UP	4.57544395261268	6.97006452356767e-06	Toll-like receptor signaling pathway: NFKB1
hsa04722__33	5.007186022347e-06	UP	4.56463652644025	7.33320540607171e-06	Neurotrophin signaling pathway: BAD
hsa04664__25	5.37796391126277e-06	DOWN	-4.54962621231187	7.87008893244762e-06	Fc epsilon RI signaling pathway: MAPK14
hsa05010__37	5.38564107591167e-06	UP	4.5493260060293	7.87519033590508e-06	Alzheimer's disease: MAPT
hsa04950__22	5.50991191319843e-06	DOWN	-4.54452270550822	8.05064112356131e-06	Maturity onset diabetes of the young: NR5A2
hsa05211__27	5.66105008791246e-06	UP	4.53881878613944	8.26504515554585e-06	Renal cell carcinoma: VEGFA*
hsa05130__55	5.72586740081367e-06	UP	4.5364171358789	8.35318699233609e-06	Pathogenic Escherichia coli infection: ACTB
hsa05166__39	5.74218238111252e-06	UP	4.53581672331376	8.37048928945728e-06	HTLV-I infection: RRAS2
hsa04064__135	5.81615203327713e-06	UP	4.53311486677065	8.47174393064166e-06	NF-kappa B signaling pathway: CCL19
hsa04912__20	6.0008257441305e-06	DOWN	-4.52651032855417	8.73396713649977e-06	GnRH signaling pathway: PLA2G4B
hsa04727__26	6.08661131463412e-06	UP	4.52350826572849	8.83146151366604e-06	GABAergic synapse: KCNJ6
hsa05032__81	6.08661131463412e-06	UP	4.52350826572849	8.83146151366604e-06	Morphine addiction: KCNJ6
hsa05032__91	6.08661131463412e-06	UP	4.52350826572849	8.83146151366604e-06	Morphine addiction: KCNJ6**
hsa05032__85	6.08661131463412e-06	UP	4.52350826572849	8.83146151366604e-06	Morphine addiction: KCNJ6*
hsa04722__85	6.3062399006216e-06	DOWN	-4.5160031086643	9.14307467073148e-06	Neurotrophin signaling pathway: BAX
hsa04914__42	6.84535743606052e-06	DOWN	-4.49859114427538	9.91705984761581e-06	Progesterone-mediated oocyte maturation: ARAF
hsa04913__47	6.92309162363274e-06	DOWN	-4.49618949401484	1.00065301236969e-05	Ovarian steroidogenesis: INSR
hsa04913__51	6.92309162363274e-06	DOWN	-4.49618949401484	1.00065301236969e-05	Ovarian steroidogenesis: INSR*
hsa04961__12	6.92309162363274e-06	DOWN	-4.49618949401484	1.00065301236969e-05	Endocrine and other factor-regulated calcium reabsorption: SLC8A1
hsa04933__59	6.94265669365197e-06	UP	4.4955890814497	1.00270960241138e-05	AGE-RAGE signaling pathway in diabetic complications: SERPINE1
hsa04071__1	7.2732170802916e-06	UP	4.48568227412497	1.04964476911428e-05	Sphingolipid signaling pathway: MAPK1
hsa04724__33 70 69	7.5974141712796e-06	UP	4.47637587936538	1.09559027074707e-05	Glutamatergic synapse: ITPR1 HOMER3 HOMER3
hsa04340__13	7.77010271039686e-06	DOWN	-4.4715725788443	1.11963366509476e-05	Hedgehog signaling pathway: GLI1*
hsa05032__38	8.12680414611066e-06	UP	4.46196597780213	1.17013524831739e-05	Morphine addiction: CACNA1A
hsa05166__32	8.49912711470247e-06	DOWN	-4.45235937675997	1.22280703281209e-05	HTLV-I infection: STAT5A
hsa04920__3	8.93747121999488e-06	DOWN	-4.44155195058754	1.28488970331832e-05	Adipocytokine signaling pathway: C15493
hsa04151__110	9.03777338234058e-06	UP	4.439150300327	1.29831622212675e-05	PI3K-Akt signaling pathway: BCL2**
hsa05216__5	9.13915057834313e-06	UP	4.43674865006646	1.31187654214719e-05	Thyroid cancer: MAPK1
hsa04662__10	9.74348609969554e-06	UP	4.42293916106835	1.39755804437618e-05	B cell receptor signaling pathway: GSK3B
hsa04668__20	1.0045833947856e-05	UP	4.41633462285186	1.43982623859813e-05	TNF signaling pathway: IKBKG
hsa04024__12	1.02003479841832e-05	UP	4.41303235374362	1.46085776389331e-05	cAMP signaling pathway: SLC9A1
hsa04620__23	1.02145067134048e-05	UP	4.41273214746105	1.46177137200973e-05	Toll-like receptor signaling pathway: CD40
hsa04151__102	1.07072265613877e-05	DOWN	-4.40252513385375	1.52995275352453e-05	PI3K-Akt signaling pathway: C8orf44-SGK3
hsa05166__89 90	1.07072265613877e-05	DOWN	-4.40252513385375	1.52995275352453e-05	HTLV-I infection: CHUK IKBKG
hsa04151__35	1.13629257781035e-05	UP	4.38961626370334	1.62241166694958e-05	PI3K-Akt signaling pathway: CCND1
hsa04064__113	1.23082960712969e-05	DOWN	-4.37220429931442	1.75605833849407e-05	NF-kappa B signaling pathway: CFLAR
hsa04723__46	1.26687390202971e-05	UP	4.3658999673805	1.80611233832612e-05	Retrograde endocannabinoid signaling: ADCY1
hsa04150__56	1.35122893289925e-05	DOWN	-4.35179027209983	1.92491217961918e-05	mTOR signaling pathway: EIF4B
hsa05200__220	1.39443625221422e-05	DOWN	-4.34488552760077	1.98495887720494e-05	Pathways in cancer: CSF1R*
hsa05169__118	1.44092561218759e-05	UP	4.33768057681915	2.04958306230165e-05	Epstein-Barr virus infection: MDM2
hsa05210__16	1.48079223290579e-05	UP	4.3316764511678	2.10469637339636e-05	Colorectal cancer: MAPK8
hsa04917__65	1.62214939099156e-05	DOWN	-4.31156263023577	2.30386901411424e-05	Prolactin signaling pathway: CYP17A1
hsa04010__66	1.63319894987228e-05	UP	4.31006159882293	2.31781029215258e-05	MAPK signaling pathway: TP53
hsa05200__211	1.78112163018283e-05	DOWN	-4.29084839673861	2.52583210801021e-05	Pathways in cancer: CXCL8
hsa04742__55	1.78821010574445e-05	UP	4.2899477778909	2.53397193717483e-05	Taste transduction: P2RX3
hsa04670__45	1.97337114499239e-05	DOWN	-4.26803271926347	2.79424595436376e-05	Leukocyte transendothelial migration: PXN
hsa04015__67	1.97868791675153e-05	DOWN	-4.26743230669833	2.79966460510251e-05	Rap1 signaling pathway: AKT3
hsa05200__226	2.40588536542223e-05	DOWN	-4.22360218944346	3.4015489854239e-05	Pathways in cancer: CDKN1A*
hsa04152__103	2.41874259059433e-05	UP	4.22240136431319	3.41715588550883e-05	AMPK signaling pathway: ULK1
hsa05218__9	2.51727672234454e-05	UP	4.21339517583617	3.55369118052997e-05	Melanoma: CCND1
hsa05169__64	2.72952872912399e-05	UP	4.19508259259954	3.85043880031831e-05	Epstein-Barr virus infection: NFKB2
hsa04520__73	2.92379766596036e-05	DOWN	-4.17947186590603	4.12139220880683e-05	Adherens junction: PARD3
hsa04310__34	3.07804966254713e-05	DOWN	-4.16776382088589	4.3355737000945e-05	Wnt signaling pathway: FOSL1
hsa04360__40 139	3.08210474999269e-05	DOWN	-4.16746361460332	4.338033576956e-05	Axon guidance: UNC5D DCC
hsa04210__51	3.50509299409802e-05	DOWN	-4.1380433989117	4.92600578602107e-05	Apoptosis: LMNA
hsa05200__210	3.50509299409802e-05	DOWN	-4.1380433989117	4.92600578602107e-05	Pathways in cancer: MMP1
hsa05132__68	3.58386476234827e-05	UP	4.13293989210805	5.03294610497189e-05	Salmonella infection: NOS2
hsa05321__123	4.09295582706201e-05	DOWN	-4.10231885128616	5.74358775134393e-05	Inflammatory bowel disease (IBD): IL5*
hsa04110__48	4.13030001198075e-05	UP	4.10021740730818	5.79166695709837e-05	Cell cycle: RB1*
hsa05160__66	4.14640343326196e-05	UP	4.09931678846048	5.80991204407101e-05	Hepatitis C: GSK3B
hsa04620__87	4.33312171538248e-05	DOWN	-4.08910977485318	6.06701617228292e-05	Toll-like receptor signaling pathway: CCL4L1
hsa04650__15	4.56300214185952e-05	UP	4.07710152355048	6.38412585595981e-05	Natural killer cell mediated cytotoxicity: TNF
hsa05161__26	4.69431868556067e-05	UP	4.07049698533399	6.56296488851822e-05	Hepatitis B: MMP9
hsa04912__14	4.74906521365791e-05	DOWN	-4.06779512879088	6.63456768510276e-05	GnRH signaling pathway: ATF4
hsa04726__39	4.77974096776427e-05	DOWN	-4.06629409737805	6.67246157387003e-05	Serotonergic synapse: CACNA1C
hsa05145__23	4.89173642469376e-05	UP	4.06089038429183	6.82373625983636e-05	Toxoplasmosis: CIITA
hsa04915__28	4.99337224679032e-05	UP	4.05608708377075	6.9603460324325e-05	Estrogen signaling pathway: KCNJ3
hsa05166__74	5.30362915947968e-05	DOWN	-4.04197738849007	7.38733816950505e-05	HTLV-I infection: NFKB1
hsa04066__11	5.40643331251288e-05	DOWN	-4.03747429425156	7.52495421793459e-05	HIF-1 signaling pathway: SLC2A1
hsa04210__10	5.42721944625888e-05	UP	4.03657367540385	7.54829410771312e-05	Apoptosis: BIRC2
hsa04152__30	5.66092050096079e-05	UP	4.02666686807912	7.8675071163501e-05	AMPK signaling pathway: ACACA
hsa05200__191	5.85172927133535e-05	DOWN	-4.01886150473237	8.12668093188406e-05	Pathways in cancer: CCND1*
hsa05213__13	5.9721606282702e-05	UP	4.01405820421128	8.28780636670584e-05	Endometrial cancer: CASP9
hsa05014__53	6.54373771857627e-05	DOWN	-3.99244335186642	9.06761326637389e-05	Amyotrophic lateral sclerosis (ALS): RAB5A
hsa05205__256	6.54373793996966e-05	DOWN	-3.99244335186642	9.06761326637389e-05	Proteoglycans in cancer: ACTB
hsa04664__46	6.97072055176494e-05	DOWN	-3.97743303773804	9.65216206099213e-05	Fc epsilon RI signaling pathway: PLA2G4B
hsa04933__61	7.00599440510591e-05	DOWN	-3.97623221260777	9.69386118350074e-05	AGE-RAGE signaling pathway in diabetic complications: MMP2
hsa05223__37	7.08597897801463e-05	UP	3.97353035606466	9.79731751264863e-05	Non-small cell lung cancer: CCND1*
hsa03320__62	7.11281952188746e-05	UP	3.97262973721696	9.82719697178422e-05	PPAR signaling pathway: UBC
hsa04210__57	7.28514890476921e-05	UP	3.96692581784817	0.000100578947774146	Apoptosis: BAK1
hsa04621__44	7.31271517291169e-05	UP	3.96602519900047	0.000100885402422181	NOD-like receptor signaling pathway: MAPK14
hsa04115__17	7.43331304103453e-05	UP	3.96212251732709	0.00010247391932578	p53 signaling pathway: TP73
hsa04961__20	8.57440294083971e-05	DOWN	-3.92789900111439	0.000118118058107315	Endocrine and other factor-regulated calcium reabsorption: CALB1*
hsa05213__29	8.90120687359293e-05	DOWN	-3.91889281263736	0.000122530166413781	Endometrial cancer: CCND1
hsa04360__125	9.55467468834738e-05	UP	3.901781054531	0.000131429236745276	Axon guidance: ENAH*
hsa05200__198	0.0001035507996014	UP	3.88226764616411	0.000142335005450644	Pathways in cancer: BCL2L1*
hsa04064__36	0.000105615908624795	UP	3.87746434564303	0.000145067465135958	NF-kappa B signaling pathway: PLCG1
hsa04062__38	0.000106400296665556	UP	3.87566310794762	0.000146038098929569	Chemokine signaling pathway: NCF1
hsa04611__92	0.000110541300937624	DOWN	-3.86635671318803	0.000151611025154596	Platelet activation: RHOA*
hsa04919__27	0.000115399226428513	DOWN	-3.85584949329816	0.000158158385455271	Thyroid hormone signaling pathway: GATA4
hsa05200__185	0.000116537535365342	DOWN	-3.85344784303762	0.000159602061917987	Pathways in cancer: HHIP
hsa04670__39	0.000119283602795363	UP	3.84774392366884	0.000163243910890376	Leukocyte transendothelial migration: MAPK14
hsa04972__21	0.000121941326255647	DOWN	-3.84234021058262	0.000166759644857613	Pancreatic secretion: KCNQ1
hsa05134__6	0.000124654806290532	DOWN	-3.8369364974964	0.00017034645892357	Legionellosis: IL1B
hsa04912__17	0.000127580727630973	DOWN	-3.83123257812762	0.000174218159315841	GnRH signaling pathway: MAPK14
hsa04340__46	0.000135099068249924	UP	3.81712288284694	0.000184350870908938	Hedgehog signaling pathway: PRKACA
hsa04510__19 23	0.000137752367305837	UP	3.81231958232586	0.000187835049468554	Focal adhesion: VCL TLN1
hsa05200__197	0.000140966912251617	UP	3.80661566295708	0.000192078918144154	Pathways in cancer: CCND1**
hsa04610__17	0.000143380592308382	UP	3.80241277500113	0.000195226183295253	Complement and coagulation cascades: PLG
hsa04510__19 26	0.000144426895364998	UP	3.80061153730573	0.000196508426061427	Focal adhesion: VCL ACTN4
hsa04620__86	0.000154545185409628	DOWN	-3.78379998548194	0.000210123302014971	Toll-like receptor signaling pathway: IL12A
hsa05205__195	0.000156609550150834	DOWN	-3.7804977163737	0.000212776098867258	Proteoglycans in cancer: CDKN1A
hsa05142__18	0.000163942434816981	DOWN	-3.76908987763613	0.000222577915477679	Chagas disease (American trypanosomiasis): FOS
hsa05169__32	0.000164534898800537	DOWN	-3.76818925878843	0.000223220992668743	Epstein-Barr virus infection: CR2
hsa05200__183	0.000169754634473538	DOWN	-3.76038389544167	0.000230136333460157	Pathways in cancer: BMP2
hsa04919__44	0.000189502270958993	UP	3.73276491744545	0.000256722975581794	Thyroid hormone signaling pathway: PFKFB2
hsa04919__99	0.000191317838225737	DOWN	-3.73036326718491	0.000258995834312796	Thyroid hormone signaling pathway: WNT4
hsa04668__36	0.000202318757717953	UP	3.71625357190423	0.000273691105653012	TNF signaling pathway: CREB3
hsa04062__35 36 37	0.000204007159758014	UP	3.71415212792626	0.000275776585025401	Chemokine signaling pathway: PARD3 PRKCZ TIAM1
hsa05150__1 2 3	0.000213911869122107	UP	3.70214387662356	0.00028895787353015	Staphylococcus aureus infection: CFD C3 CFB
hsa04917__71	0.000216201815036321	UP	3.69944202008045	0.00029163188115811	Prolactin signaling pathway: CCND1*
hsa05221__27	0.000216201815036321	DOWN	-3.69944202008045	0.00029163188115811	Acute myeloid leukemia: PIM2
hsa05162__93	0.000242672235756581	UP	3.67002180438882	0.000327102676460987	Measles: TP53
hsa04151__5	0.000244387839827183	DOWN	-3.66822056669342	0.000329179033000198	PI3K-Akt signaling pathway: EIF4B
hsa05134__7	0.000277605660296378	UP	3.63549808189355	0.000373654037032159	Legionellosis: IL18
hsa05134__68	0.000294218799404583	UP	3.62048776776517	0.000395731656464718	Legionellosis: TNF
hsa05205__369	0.000298342243448633	DOWN	-3.61688529237436	0.000400990754964221	Proteoglycans in cancer: HOXD10
hsa05152__69	0.000300772516897676	UP	3.61478384839639	0.000403968233917608	Tuberculosis: HLA-DMA
hsa04620__76	0.000306397221573429	DOWN	-3.6099805478753	0.000411228842383196	Toll-like receptor signaling pathway: CCL3L3
hsa05200__223	0.000323121781408851	DOWN	-3.5961710588772	0.000433056938136398	Pathways in cancer: CCND1****
hsa05221__17	0.000323121781408851	DOWN	-3.5961710588772	0.000433056938136398	Acute myeloid leukemia: CCND1
hsa04010__134	0.000329516000484337	UP	3.59106755207355	0.000441311878054219	MAPK signaling pathway: ATF4*
hsa05321__122	0.000341874606448533	DOWN	-3.58146095103138	0.000457537311621648	Inflammatory bowel disease (IBD): IL4**
hsa04660__35	0.000346619870159173	DOWN	-3.57785847564057	0.000463557819237784	T cell receptor signaling pathway: NFATC1
hsa05200__187	0.000356295799690425	UP	3.57065352485895	0.000476159180382865	Pathways in cancer: WNT16*
hsa04115__49	0.000366643104084623	UP	3.56314836779476	0.000489639227132201	p53 signaling pathway: MDM2*
hsa04064__142	0.000367062783157155	UP	3.56284816151219	0.000489851540875209	NF-kappa B signaling pathway: NFKB2*
hsa05200__201	0.000378565338318941	UP	3.55474259188287	0.000504843343294032	Pathways in cancer: PDGFB
hsa04728__71 72	0.000389515448623787	DOWN	-3.54723743481868	0.00051907767940716	Dopaminergic synapse: CLOCK ARNTL
hsa04933__28	0.000395776085173875	DOWN	-3.54303454686273	0.000527046962467549	AGE-RAGE signaling pathway in diabetic complications: VCAM1
hsa05222__32	0.000447833830274819	UP	3.51031206206286	0.000595948843545598	Small cell lung cancer: BIRC8
hsa04750__51	0.000497789545754376	DOWN	-3.48209267150151	0.000661489785341211	Inflammatory mediator regulation of TRP channels: TRPV4
hsa04750__61	0.000497789545754376	DOWN	-3.48209267150151	0.000661489785341211	Inflammatory mediator regulation of TRP channels: TRPV4*
hsa04015__27	0.000507362265925869	DOWN	-3.47698916469786	0.000673734061960924	Rap1 signaling pathway: RALA
hsa04064__2	0.000509639259463551	UP	3.47578833956759	0.000676279780036732	NF-kappa B signaling pathway: BCL2L1
hsa04380__69	0.000512498897655735	UP	3.47428730815475	0.000679594515663462	Osteoclast differentiation: NFKB2
hsa04015__100 101 48	0.000522917907508471	DOWN	-3.46888359506854	0.000692921543165316	Rap1 signaling pathway: PRKCI PARD6A PARD3
hsa04022__9	0.000533534053012398	UP	3.46347988198232	0.000706490828478009	cGMP-PKG signaling pathway: ITPR1
hsa04071__68	0.000581899726813869	DOWN	-3.44006379194205	0.000769992666678353	Sphingolipid signaling pathway: NFKB1
hsa04666__38	0.000594942657097013	DOWN	-3.4340596662907	0.000786697574022018	Fc gamma R-mediated phagocytosis: CFL1
hsa05321__46	0.000598908285046674	UP	3.43225842859529	0.000791384435726231	Inflammatory bowel disease (IBD): IFNG*
hsa04151__28	0.000608257292131315	DOWN	-3.42805554063934	0.000803173191788293	PI3K-Akt signaling pathway: BCL2L11
hsa05133__27	0.000612305435718348	DOWN	-3.42625430294394	0.000807950782103073	Pertussis: IRF3
hsa05205__103	0.000623223382725573	UP	3.42145100242286	0.000821780165713229	Proteoglycans in cancer: CCND1
hsa04914__39	0.000641352092386134	DOWN	-3.4136456390761	0.000845091571944983	Progesterone-mediated oocyte maturation: PIK3R5
hsa04014__27	0.000662878857237394	DOWN	-3.40463945059907	0.000872844690083436	Ras signaling pathway: ABL1
hsa04973__5	0.000663607855222308	UP	3.4043392443165	0.000873192689049522	Carbohydrate digestion and absorption: SLC2A5
hsa05150__13	0.000690353658943763	UP	3.39353181814407	0.000907749842655934	Staphylococcus aureus infection: C5AR1
hsa04750__60	0.000712622202559024	DOWN	-3.38482583594961	0.000936375607418466	Inflammatory mediator regulation of TRP channels: TRPV3
hsa04022__58	0.000718883806362667	DOWN	-3.38242418568907	0.000943943167124704	cGMP-PKG signaling pathway: MYH7
hsa04064__93	0.000741198182884136	UP	3.37401840977718	0.000972563816787214	NF-kappa B signaling pathway: PLAU
hsa04728__61	0.000772511863294175	UP	3.36261057103961	0.00101294472514289	Dopaminergic synapse: KCNJ3
hsa05220__19 41	0.000825357283412018	DOWN	-3.34429798780298	0.00108148280023095	Chronic myeloid leukemia: SMAD4 SMAD3
hsa04115__16	0.000868340735480109	DOWN	-3.33018829252231	0.0011370120153081	p53 signaling pathway: PPM1D
hsa04662__6	0.000955473454737218	UP	3.30346993337379	0.00125023302329473	B cell receptor signaling pathway: NFKB1
hsa04020__64	0.00102306207528737	DOWN	-3.28425673128947	0.00133681059768078	Calcium signaling pathway: C01330*
hsa04020__12	0.00102306207528737	DOWN	-3.28425673128947	0.00133681059768078	Calcium signaling pathway: C01330
hsa05200__5	0.00102633633467982	UP	3.28335611244176	0.00133922637004401	Pathways in cancer: CASP3*
hsa05210__7	0.00102633633467982	UP	3.28335611244176	0.00133922637004401	Colorectal cancer: CASP3*
hsa05161__44	0.00103842510570983	UP	3.28005384333352	0.00135406021764662	Hepatitis B: CXCL8
hsa04380__38	0.00112086239055355	DOWN	-3.25843899098865	0.00146054121487526	Osteoclast differentiation: FOS
hsa05142__44	0.00128655594121998	UP	3.2191119679723	0.00167528663447841	Chagas disease (American trypanosomiasis): PLCB1
hsa04024__24	0.0013840951206598	DOWN	-3.19809752819257	0.00180104898318543	cAMP signaling pathway: PLN
hsa05133__96	0.00140002860720194	DOWN	-3.19479525908432	0.00182052162832696	Pertussis: IL1B
hsa04014__62	0.0014176033705551	DOWN	-3.19119278369351	0.00184210009216669	Ras signaling pathway: RASSF5
hsa05200__194	0.00142055219631667	DOWN	-3.19059237112838	0.00184465623834072	Pathways in cancer: BCL2
hsa05152__68	0.00149458875590382	UP	3.17588226328257	0.00193945598918734	Tuberculosis: CD74
hsa04621__21 31 41	0.00170333693801998	DOWN	-3.13775606539648	0.0022088130479914	NOD-like receptor signaling pathway: NLRP3 CARD8 CASP1
hsa04066__54	0.00170508212882502	DOWN	-3.13745585911391	0.00220955125521532	HIF-1 signaling pathway: SERPINE1
hsa05215__24	0.00172438806896519	DOWN	-3.13415359000567	0.00223302907069992	Prostate cancer: CDKN1A
hsa04152__52	0.00180363905619327	UP	3.1209445135727	0.00233404806238785	AMPK signaling pathway: PCK1
hsa04910__12	0.00185580017136003	DOWN	-3.1125387376608	0.00239989574809738	Insulin signaling pathway: FASN
hsa04933__63	0.00187095588091466	DOWN	-3.11013708740026	0.00241783088049426	AGE-RAGE signaling pathway in diabetic complications: SELE
hsa04390__90	0.00187857629682862	UP	3.10893626226999	0.00242601021425497	Hippo signaling pathway: BBC3
hsa04720__4 15	0.00199635665223159	UP	3.09092388531594	0.00257634213567524	Long-term potentiation: CREBBP ATF4
hsa04510__43	0.0020515374732389	UP	3.08281831568661	0.00264573707084138	Focal adhesion: BAD
hsa04550__25	0.00206815406081165	UP	3.08041666542607	0.00266533709208854	Signaling pathways regulating pluripotency of stem cells: MAPK1
hsa04725__50	0.00207441704634714	DOWN	-3.07951604657837	0.00267157616866776	Cholinergic synapse: BCL2
hsa04622__6	0.0022122413791268	UP	3.06030284449404	0.00284712435025977	RIG-I-like receptor signaling pathway: NFKB1
hsa04930__10	0.00239154296769518	UP	3.03688675445377	0.00307577634243617	Type II diabetes mellitus: C00031
hsa04370__15	0.00253841439833787	UP	3.01887437749971	0.00326243546817843	VEGF signaling pathway: PLA2G4B
hsa04520__64	0.00256114323786573	DOWN	-3.01617252095661	0.00328939722758011	Adherens junction: CTNND1**
hsa04740__13	0.00258917561938125	DOWN	-3.01287025184836	0.00332312909072225	Olfactory transduction: CNGA3
hsa05220__21	0.00277969626509128	DOWN	-2.9912553995035	0.00356522135297372	Chronic myeloid leukemia: NFKBIA
hsa05211__3	0.00287968214518681	UP	2.98044797333106	0.00369094321337381	Renal cell carcinoma: VEGFA
hsa05161__32	0.00299462021402815	DOWN	-2.96843972202836	0.00383564511394608	Hepatitis B: STAT3
hsa04010__87	0.00308055070652944	UP	2.9597337398339	0.00394302096564634	MAPK signaling pathway: STK3
hsa05169__93	0.00308956720462374	DOWN	-2.9588331209862	0.0039518698281062	Epstein-Barr virus infection: PLCG1
hsa04062__22 41	0.00309257804736391	DOWN	-2.95853291470363	0.00395303003469169	Chemokine signaling pathway: CRK PTK2B
hsa04010__12	0.00316257005915161	UP	2.95162817020457	0.00403974788657095	MAPK signaling pathway: PLA2G4B
hsa05200__193	0.00345387946963099	UP	2.92430939849092	0.00440885837189988	Pathways in cancer: NOS2
hsa04670__2	0.00349069980258718	UP	2.92100712938268	0.00445283430350394	Leukocyte transendothelial migration: MMP2
hsa04068__42	0.0036345955488079	DOWN	-2.90839846551484	0.00463324629322255	FoxO signaling pathway: CDKN2D
hsa04024__2	0.00374424188637929	UP	2.89909207075524	0.00476978339288589	cAMP signaling pathway: CACNA1C
hsa04510__47	0.00375860669565267	UP	2.89789124562497	0.00478483874060391	Focal adhesion: CCND1
hsa05164__35	0.00397260160503368	UP	2.88047928123605	0.00505383779001915	Influenza A: IL18
hsa05134__10	0.00401059607321037	DOWN	-2.87747721841038	0.0050987212595144	Legionellosis: NFKB1
hsa04360__123	0.00412265300634485	DOWN	-2.86877123621592	0.00523763691610681	Axon guidance: ENAH
hsa04976__59	0.00416589527946451	UP	2.86546896710767	0.00528899812845528	Bile secretion: ABCB4
hsa04931__135	0.00417380157882134	UP	2.86486855454254	0.00529545791127975	Insulin resistance: SREBF1**
hsa04115__54	0.00421353764698327	DOWN	-2.86186649171686	0.00534226534323992	p53 signaling pathway: PERP
hsa05162__105	0.00424959316698775	UP	2.85916463517375	0.00538434629856372	Measles: GSK3B
hsa04064__130	0.00427378539348055	UP	2.85736339747835	0.00540770555848481	NF-kappa B signaling pathway: TNF*
hsa05020__46	0.00427378539348055	DOWN	-2.85736339747835	0.00540770555848481	Prion diseases: PRKACA
hsa04914__34	0.00446765457289589	DOWN	-2.84325370219767	0.00564920790206688	Progesterone-mediated oocyte maturation: MAPK14
hsa04064__3	0.00467384081773144	DOWN	-2.82884380063443	0.00590594949328674	NF-kappa B signaling pathway: BCL2
hsa05166__26	0.00467822651702879	DOWN	-2.82854359435186	0.00590751856552224	HTLV-I infection: NFATC1
hsa04012__25	0.00468700909484793	UP	2.82794318178673	0.00591463404245753	ErbB signaling pathway: CDKN1B
hsa04670__28 41 49	0.00483409291605314	UP	2.81803637446199	0.00609614804648581	Leukocyte transendothelial migration: ACTB CTNNA1 CTNNB1
hsa04064__95	0.00513130623933824	UP	2.79882317237767	0.00646661597834779	NF-kappa B signaling pathway: BCL2L1**
hsa04310__20	0.0051695965239355	UP	2.79642152211713	0.0065105039332941	Wnt signaling pathway: MAPK8
hsa05169__11	0.0052959029479551	DOWN	-2.59738475677481	0.00666510491574524	Epstein-Barr virus infection: HLA-A
hsa05215__8	0.00551581050925694	DOWN	-2.7754070823374	0.00693722084798781	Prostate cancer: NFKBIA
hsa05132__6	0.00554643843692887	DOWN	-2.77360584464199	0.0069710754668825	Salmonella infection: NFKB1
hsa04210__71	0.00559266814193968	UP	2.77090398809888	0.00702448090822504	Apoptosis: GADD45G
hsa05221__29	0.0056496430963898	DOWN	-2.76760171899064	0.00709130218979053	Acute myeloid leukemia: RPS6KB1
hsa04630__34	0.00565484851273405	UP	2.76730151270807	0.00709309770055226	Jak-STAT signaling pathway: AOX1
hsa04510__44	0.00566005825509876	DOWN	-2.7670013064255	0.0070948962383793	Focal adhesion: BCL2
hsa04750__90	0.0058290729356415	DOWN	-2.75739470538334	0.00730188536404691	Inflammatory mediator regulation of TRP channels: C01245**
hsa05161__31	0.00593700421012492	UP	2.75139057973199	0.00743213251887057	Hepatitis B: ELK1
hsa04725__25	0.00638696696992432	UP	2.72737407712658	0.00799008717475885	Cholinergic synapse: CACNA1A
hsa04010__131	0.00667749875992046	DOWN	-2.71266396928077	0.00834798414497043	MAPK signaling pathway: MYC
hsa04151__37	0.00692341683774721	DOWN	-2.70065571797807	0.00864966771152061	PI3K-Akt signaling pathway: G6PC
hsa05210__23	0.00694845069459698	DOWN	-2.6994548928478	0.00867517531903503	Colorectal cancer: CCND1
hsa05161__194	0.0069735658276589	UP	2.69825406771752	0.00870075045828092	Hepatitis B: TNF*
hsa04620__34	0.0071388110627022	DOWN	-2.69044870437077	0.00890101259908257	Toll-like receptor signaling pathway: IL1B
hsa04727__49	0.00779370966458365	DOWN	-2.66102848867914	0.00971112762583069	GABAergic synapse: GABRR3
hsa04210__58	0.00829393162195779	DOWN	-2.64001404889941	0.0103275662807546	Apoptosis: BID*
hsa04668__138	0.0084196683802268	UP	2.63491054209576	0.0104771899910239	TNF signaling pathway: NFKB1*
hsa04933__65	0.00863809963599156	DOWN	-2.6262045599013	0.0107418856492575	AGE-RAGE signaling pathway in diabetic complications: COL1A1
hsa04015__3	0.00877621205389951	UP	2.62080084681509	0.0109064169638077	Rap1 signaling pathway: MAPK1
hsa05162__27 70	0.00917026736685865	UP	2.60579053268671	0.011388587166112	Measles: STAT1 GNB2L1
hsa05160__37	0.00927541397890183	DOWN	-2.60068702588306	0.0115115606779105	Hepatitis C: STAT3
hsa05110__13	0.00935676988957766	DOWN	-2.59888578818765	0.0116048650973706	Vibrio cholerae infection: C00238
hsa05200__129 130	0.00980803849841789	DOWN	-2.582674648929	0.0121485196694313	Pathways in cancer: CTBP1 HDAC1
hsa05220__12 13	0.00980803849841789	DOWN	-2.582674648929	0.0121485196694313	Chronic myeloid leukemia: HDAC1 CTBP1
hsa04620__29	0.00999737719270056	UP	2.57607011071251	0.0123748825725193	Toll-like receptor signaling pathway: CXCL8
hsa04530__20 62	0.0104038205898192	UP	2.56226062171441	0.012869505522232	Tight junction: ACTB SHROOM1
hsa04360__33 134	0.0110032020684889	DOWN	-2.54274721334751	0.0136019846622965	Axon guidance: NCK1 PAK4
hsa04931__67	0.0110221124713926	UP	2.54214680078238	0.013616403243752	Insulin resistance: IKBKB**
hsa05200__75	0.0113287877752285	UP	2.53254019974021	0.0139860658539121	Pathways in cancer: MAPK8
hsa04660__41 46	0.0115242792874912	DOWN	-2.52653607408886	0.0142180701124071	T cell receptor signaling pathway: GRAP2 LCP2
hsa05200__202	0.0117527907552675	UP	2.51963132958981	0.0144904815151888	Pathways in cancer: FIGF*
hsa04520__44 52 45	0.0117628165762156	DOWN	-2.51933112330724	0.0144933326863667	Adherens junction: ACTB ACTN4 CTNNA1
hsa04010__68	0.0120057229659529	DOWN	-2.51212617252562	0.0147829314895318	MAPK signaling pathway: ATF2
hsa04210__119	0.0120159398706518	DOWN	-2.51182596624305	0.0147858225389356	Apoptosis: BCL2*
hsa04668__38	0.0121288355393535	UP	2.50852369713481	0.0149149751167836	TNF signaling pathway: CEBPB
hsa04330__11	0.0123365107639961	UP	2.50251957148345	0.015160434091268	Notch signaling pathway: PTCRA
hsa04650__14	0.0138225690477822	UP	2.46199172333683	0.0169755602880933	Natural killer cell mediated cytotoxicity: CSF2
hsa04024__107 64	0.0138805220380428	UP	2.46049069192399	0.0170355982426404	cAMP signaling pathway: NFKBIA NFKB1
hsa05160__70	0.0139736930889075	DOWN	-2.45808904166345	0.0171387528159642	Hepatitis C: CDKN1A
hsa04668__153	0.0142684204599928	UP	2.45058388459926	0.0174888206420916	TNF signaling pathway: MAPK14*
hsa03320__45	0.0144840065969014	UP	2.44518017151304	0.0177414917832971	PPAR signaling pathway: PDPK1
hsa05200__218	0.014532302898353	DOWN	-2.44397934638277	0.0177890535153129	Pathways in cancer: CSF3R*
hsa05016__48	0.014985817877865	DOWN	-2.43287171392777	0.0183203329814628	Huntington's disease: HIP1
hsa05016__46	0.014985817877865	DOWN	-2.43287171392777	0.0183203329814628	Huntington's disease: HTT**
hsa04152__49	0.0153245849053547	UP	2.42476614429845	0.0187222984636941	AMPK signaling pathway: GYS1
hsa04024__34	0.0156700755009458	DOWN	-2.41666057466912	0.0191319505303945	cAMP signaling pathway: ATP2B1
hsa04726__41	0.0159697603554979	UP	2.40975583017007	0.0194725371239329	Serotonergic synapse: HTR3C
hsa04742__57	0.0159697603554979	UP	2.40975583017007	0.0194725371239329	Taste transduction: HTR3C
hsa05212__10	0.0161413793296705	UP	2.40585314849669	0.0196690348641057	Pancreatic cancer: BCL2L1
hsa04380__16	0.0161546470764169	UP	2.40555294221412	0.01967244449552	Osteoclast differentiation: NFKB1
hsa04920__10	0.0164220223498578	UP	2.39954881656277	0.0199850906705848	Adipocytokine signaling pathway: PCK1
hsa04723__67	0.0169269292364577	UP	2.38844118410777	0.0205862136150836	Retrograde endocannabinoid signaling: PRKACA
hsa04950__8	0.0187802373755577	UP	2.35001477993912	0.0228253984661532	Maturity onset diabetes of the young: NEUROD1
hsa05161__66 67	0.0188409075268298	DOWN	-2.34881395480885	0.0228843343522387	Hepatitis B: NFKB1 NFKBIA
hsa04660__43	0.01931694136669	UP	2.33950756004925	0.0234473726279138	T cell receptor signaling pathway: RHOA
hsa05200__121 122	0.0199626574838771	DOWN	-2.32719910246398	0.0241998925240033	Pathways in cancer: SMAD2 SMAD4
hsa05212__38 39	0.0199626574838771	DOWN	-2.32719910246398	0.0241998925240033	Pancreatic cancer: SMAD2 SMAD4
hsa04151__51	0.0200426781160381	UP	2.32569807105114	0.0242812328691396	PI3K-Akt signaling pathway: NOS3
hsa04012__24	0.0206271356250264	DOWN	-2.31489064487871	0.0249731880408664	ErbB signaling pathway: CDKN1A
hsa04115__22	0.0209915732443657	DOWN	-2.30828610666222	0.0253980464431185	p53 signaling pathway: STEAP3
hsa05212__14	0.0210751782101747	UP	2.30678507524938	0.0254827927007196	Pancreatic cancer: MAPK1
hsa05142__49	0.0213108173592675	DOWN	-2.30258218729344	0.0257511420051857	Chagas disease (American trypanosomiasis): ADCY1
hsa05142__67	0.021927311350126	UP	2.291774761121	0.0264790604285904	Chagas disease (American trypanosomiasis): IFNGR1*
hsa04931__144	0.0220663984548232	DOWN	-2.28937311086046	0.0266299053928149	Insulin resistance: C00533*
hsa04920__12	0.0222062314288389	DOWN	-2.28697146059992	0.0267814562610965	Adipocytokine signaling pathway: C00165
hsa04727__47	0.0224351591768003	UP	2.28306877892654	0.0270401950565797	GABAergic synapse: CACNA1A*
hsa04912__46	0.0228991332749555	DOWN	-2.27526341557979	0.0275817124510522	GnRH signaling pathway: JUN
hsa05164__99	0.0230616704345676	UP	2.27256155903668	0.0277596917018274	Influenza A: FDPS
hsa04660__40 41	0.0237033206058667	DOWN	-2.26205433914681	0.028513789640476	T cell receptor signaling pathway: LAT GRAP2
hsa04210__24	0.0260222550470446	UP	2.2260295852387	0.0312833123694157	Apoptosis: CASP10
hsa05200__184	0.0264272297799066	DOWN	-2.22002545958735	0.0317498495885195	Pathways in cancer: GLI1
hsa04210__52	0.0265293202361034	DOWN	-2.21852442817451	0.0318521359256474	Apoptosis: PARP2
hsa05162__44	0.0273793881658123	UP	2.20621597058924	0.0328517690699626	Measles: PRKCQ
hsa05145__33	0.0277812253276422	DOWN	-2.20051205122046	0.0332914045858671	Toxoplasmosis: STAT3
hsa05169__125	0.0277812253276422	DOWN	-2.20051205122046	0.0332914045858671	Epstein-Barr virus infection: STAT3
hsa05016__12	0.0280590876326412	DOWN	-2.19660936954708	0.0336029481591668	Huntington's disease: REST
hsa04933__57	0.0281235488165353	DOWN	-2.19570875069937	0.0336586931377515	AGE-RAGE signaling pathway in diabetic complications: FIGF
hsa05133__30	0.0282312677532686	DOWN	-2.19420771928654	0.0337661057341768	Pertussis: NOS2
hsa04650__25	0.0283176987035416	DOWN	-2.19300689415627	0.0338479363002256	Natural killer cell mediated cytotoxicity: SH2D1B
hsa04360__3	0.0294622130412824	DOWN	-2.17739616746275	0.0351935780702922	Axon guidance: GNAI1
hsa05212__8	0.0305768886736894	UP	2.16268605961694	0.0365018893379049	Pancreatic cancer: NFKB1
hsa03320__56	0.0307855144732255	DOWN	-2.15998420307383	0.0367276074255179	PPAR signaling pathway: FADS2
hsa04920__26	0.0319429346449388	DOWN	-2.14527409522802	0.0380842475874619	Adipocytokine signaling pathway: NPY
hsa05150__66	0.0331870160299675	UP	2.12996357481707	0.0395424242994984	Staphylococcus aureus infection: IL10
hsa04912__43	0.0344979545335728	DOWN	-2.11435284812356	0.0410783628444762	GnRH signaling pathway: PTK2B
hsa05161__97	0.0356942617823016	UP	2.10054335912545	0.0424759454648161	Hepatitis B: BCL2
hsa04014__58 59	0.0364664996681031	DOWN	-2.09183737693099	0.0433674385293454	Ras signaling pathway: STK4 STK4
hsa04014__35	0.0370617911034701	UP	2.0852328387145	0.0440475050496017	Ras signaling pathway: NFKB1
hsa04014__54	0.0373351015956844	UP	2.08223077588882	0.0443442831215493	Ras signaling pathway: RHOA
hsa04660__14	0.0392680941098967	UP	2.06151654239166	0.0466107067798458	T cell receptor signaling pathway: NFKB1
hsa04010__61	0.0400763927391737	UP	2.05311076647977	0.047540114871785	MAPK signaling pathway: ATF4
hsa04370__39	0.0407508693173015	DOWN	-2.04620602198071	0.0483097056449271	VEGF signaling pathway: RAC1
hsa04670__10	0.0432033008546537	UP	2.02188931309274	0.0511847429419258	Leukocyte transendothelial migration: BCAR1
hsa04115__21	0.0440795632977661	DOWN	-2.01348353718085	0.0521899807413375	p53 signaling pathway: DDB2
hsa04923__31	0.0441427234962953	UP	2.01288312461571	0.0522318497793066	Regulation of lipolysis in adipocytes: PRKACA*
hsa04014__79	0.0445869872354083	DOWN	-2.00868023665976	0.0527243228542053	Ras signaling pathway: RAC1**
hsa04062__44	0.0455192557157035	UP	1.9999742544653	0.0537928814401301	Chemokine signaling pathway: MAPK1
hsa04932__7	0.0484835105100647	DOWN	-1.97325589531679	0.0572599096470217	Non-alcoholic fatty liver disease (NAFLD): SREBF1
hsa04650__16	0.0501132438835785	DOWN	-1.95914620003611	0.0591474781766608	Natural killer cell mediated cytotoxicity: PRKCA
hsa05321__83	0.0507139210757835	DOWN	-1.95404269323246	0.0598188686135576	Inflammatory bowel disease (IBD): IL2
hsa04921__59	0.0510700697414819	DOWN	-1.95104063040679	0.0602011675308936	Oxytocin signaling pathway: CCND1
hsa04912__19	0.0521511037528613	DOWN	-1.94203444192976	0.0614369429163802	GnRH signaling pathway: MAPK7
hsa05321__94	0.0528456077593828	UP	1.93633052256097	0.0622161008645866	Inflammatory bowel disease (IBD): IL22
hsa04921__60	0.0533622791681295	DOWN	-1.93212763460503	0.0627850485641298	Oxytocin signaling pathway: ELK1
hsa04724__65	0.0543329415922768	DOWN	-1.92432227125827	0.063887107166388	Glutamatergic synapse: GRM3
hsa04742__46	0.05463458368145	DOWN	-1.92192062099773	0.0642016152204156	Taste transduction: P2RY1
hsa05220__22	0.0572160505104059	UP	1.9018068000657	0.0671930993181579	Chronic myeloid leukemia: CDKN1B
hsa04115__25	0.0572946407459394	DOWN	-1.90120638750057	0.0672433666218739	p53 signaling pathway: CD82
hsa05321__81	0.0582447457133073	DOWN	-1.89400143671894	0.0683157785239104	Inflammatory bowel disease (IBD): IL13
hsa04115__18	0.0582846157997263	DOWN	-1.89370123043638	0.0683198958750379	p53 signaling pathway: CCNG1
hsa04630__36	0.0583644239943495	DOWN	-1.89310081787124	0.0683707934447523	Jak-STAT signaling pathway: GFAP
hsa04115__15	0.0584443229466505	UP	1.89250040530611	0.0684217338422157	p53 signaling pathway: TSC2
hsa04933__27	0.0587648278203862	UP	1.89009875504556	0.0687541167338143	AGE-RAGE signaling pathway in diabetic complications: TNF
hsa05016__55	0.0598981085279667	UP	1.88169297913367	0.0700364318133476	Huntington's disease: TGM2
hsa05220__50	0.0599389157518192	DOWN	-1.8813927728511	0.0700405613791469	Chronic myeloid leukemia: MAPK1
hsa05215__46	0.060718643697413	DOWN	-1.87568885348232	0.0709076019312859	Prostate cancer: MTOR
hsa04662__29	0.0617155582205874	UP	1.8684839027007	0.0720270396872569	B cell receptor signaling pathway: RAC1
hsa05145__29	0.062895690351122	DOWN	-1.86007812678881	0.0733587847112094	Toxoplasmosis: C06314
hsa04370__37	0.0685762457489426	UP	1.82135151633759	0.0799347182148034	VEGF signaling pathway: CASP9
hsa04380__20	0.0692633192935114	UP	1.81684842209907	0.0806855405781202	Osteoclast differentiation: MAP2K1
hsa04910__57	0.0728798421568264	DOWN	-1.79373253834137	0.0848458633287961	Insulin signaling pathway: GCK
hsa05211__23	0.0730238156845709	DOWN	-1.79283191949366	0.0849608357097887	Renal cell carcinoma: PDGFB
hsa05223__8	0.0748677034632747	DOWN	-1.7814240807561	0.087052236885825	Non-small cell lung cancer: CASP9
hsa04010__63	0.0754578227512877	UP	1.77782160536529	0.0876841366417251	MAPK signaling pathway: MAX
hsa04950__16	0.0761013974951783	UP	1.77391892369191	0.0883773336795056	Maturity onset diabetes of the young: PAX4
hsa04010__57	0.0763999385387879	UP	1.7721176859965	0.0886144966138164	MAPK signaling pathway: NLK
hsa05131__12	0.0763999385387879	DOWN	-1.7721176859965	0.0886144966138164	Shigellosis: ARPC5
hsa04932__14	0.0772007195140357	UP	1.76731438547542	0.0894880641374911	Non-alcoholic fatty liver disease (NAFLD): PKLR
hsa04919__39	0.079283971944371	DOWN	-1.75500592789015	0.0918462289047307	Thyroid hormone signaling pathway: ESR1
hsa04742__67	0.079438182898502	UP	1.75410530904245	0.0919681735466946	Taste transduction: PRKACA
hsa05221__13	0.0808370832780056	DOWN	-1.74599973941312	0.0935300982015841	Acute myeloid leukemia: NFKB1
hsa04370__23	0.0821501333586058	DOWN	-1.73849458234893	0.0949908311266586	VEGF signaling pathway: PTK2
hsa04360__89	0.0827333290521344	DOWN	-1.73519231324069	0.0956063501162119	Axon guidance: CAMK2A
hsa04062__8 41	0.0836948834470942	DOWN	-1.72978860015447	0.0966580737535894	Chemokine signaling pathway: PXN PTK2B
hsa04062__33	0.0839635819025748	UP	1.72828756874163	0.0969088270239177	Chemokine signaling pathway: WAS
hsa05166__5	0.0854812246650606	DOWN	-1.71988179282974	0.098599890206046	HTLV-I infection: SLC2A1
hsa05152__6	0.0861933432335222	DOWN	-1.71597911115636	0.0993603018010971	Tuberculosis: IL10
hsa05205__145	0.0873538016727539	DOWN	-1.70967477922244	0.100636292668979	Proteoglycans in cancer: PXN
hsa04062__25	0.0881344261865017	UP	1.7054718912665	0.101473398777228	Chemokine signaling pathway: ROCK1
hsa04151__27	0.0888643160261054	UP	1.70156920959312	0.102251102151287	PI3K-Akt signaling pathway: FASLG
hsa04115__50	0.0898261277743545	DOWN	-1.69646570278947	0.103294549625466	p53 signaling pathway: RCHY1
hsa04360__108	0.0930538506405717	DOWN	-1.67965415096568	0.106940786149012	Axon guidance: CFL1
hsa05152__120	0.0932879192456365	DOWN	-1.67845332583541	0.107144254439212	Tuberculosis: TGFB1
hsa04912__33	0.0934051305868583	UP	1.67785291327028	0.107213341705991	GnRH signaling pathway: ELK1
hsa05161__29	0.0936986759181117	UP	1.67635188185744	0.107484622741228	Hepatitis B: NFKB1
hsa03320__43	0.0941698871046777	DOWN	-1.6739502315969	0.107959254343923	PPAR signaling pathway: ILK
hsa04666__30 44	0.0946429963163038	DOWN	-1.67154858133636	0.108435481755082	Fc gamma R-mediated phagocytosis: C04637 GSN
hsa05145__4 5	0.0967956072991668	UP	1.66074115516392	0.110834214573513	Toxoplasmosis: MAP3K7 TAB1
hsa04933__25	0.0969767449419579	DOWN	-1.65984053631622	0.11097399740922	AGE-RAGE signaling pathway in diabetic complications: IL1A
hsa04726__71	0.0974611040385266	UP	1.65743888605568	0.111460386176745	Serotonergic synapse: CACNA1A
hsa04670__35	0.100221757298966	UP	1.64392960334014	0.114547860075886	Leukocyte transendothelial migration: PTK2
hsa04012__23	0.100283806007817	DOWN	-1.64362939705757	0.114549101208929	ErbB signaling pathway: RPS6KB1
hsa04971__37	0.10323480056305	DOWN	-1.62951970177689	0.11784823223449	Gastric acid secretion: KCNQ1
hsa04810__29	0.104961026010661	DOWN	-1.62141413214757	0.119746064282958	Regulation of actin cytoskeleton: ACTN4
hsa04911__54	0.105218700643054	DOWN	-1.6202133070173	0.119967195696783	Insulin secretion: RAB3A
hsa04932__95	0.106319423016345	UP	1.61510980021365	0.121148693661438	Non-alcoholic fatty liver disease (NAFLD): IL1A
hsa04961__17	0.107363717736692	DOWN	-1.61030649969257	0.122264500380148	Endocrine and other factor-regulated calcium reabsorption: CALB1
hsa04071__69	0.107691720788078	UP	1.60880546827973	0.122563745221562	Sphingolipid signaling pathway: RAC1
hsa04919__18	0.107954694108936	DOWN	-1.60760464314946	0.122788662367246	Thyroid hormone signaling pathway: STAT1
hsa04066__26	0.12176362013891	DOWN	-1.54756338663594	0.138411277822754	HIF-1 signaling pathway: C01245
hsa04915__40	0.122270853062526	UP	1.54546194265797	0.138903828841891	Estrogen signaling pathway: CREB3**
hsa05120__18	0.126090728066885	DOWN	-1.52985121596445	0.143156784312796	Epithelial cell signaling in Helicobacter pylori infection: CCL5
hsa04360__131	0.12788480634251	UP	1.52264626518283	0.145018437608676	Axon guidance: RAC1****
hsa05100__15	0.12788480634251	DOWN	-1.52264626518283	0.145018437608676	Bacterial invasion of epithelial cells: CTNNA1
hsa04666__42	0.130383999875801	UP	1.5127394578581	0.14776036329836	Fc gamma R-mediated phagocytosis: MYO10
hsa04950__1	0.130460054663107	DOWN	-1.51243925157553	0.14776036329836	Maturity onset diabetes of the young: HNF1B
hsa04664__47	0.131302135823002	DOWN	-1.50913698246729	0.148624526030976	Fc epsilon RI signaling pathway: MAPK8
hsa05160__22 23	0.13486815259882	UP	1.49532749346918	0.152569090146407	Hepatitis C: STAT1 IRF9
hsa04014__37	0.136362734140404	DOWN	-1.4896235741004	0.154167014109398	Ras signaling pathway: FASLG
hsa04210__70	0.141735265527289	DOWN	-1.46950975316837	0.160144656599986	Apoptosis: CFLAR*
hsa04922__37	0.143205988108827	DOWN	-1.46410604008215	0.161709165658946	Glucagon signaling pathway: PYGB
hsa05142__7	0.147772412689389	DOWN	-1.44759469454093	0.166765383449467	Chagas disease (American trypanosomiasis): C1QA
hsa05215__30	0.149884535049486	UP	1.44008953747674	0.169047443792307	Prostate cancer: TP53
hsa04670__73	0.155658456205715	UP	1.41997571654471	0.175454252675788	Leukocyte transendothelial migration: MYL12B*
hsa05010__49	0.162862431481287	UP	1.39565900765674	0.183456277346569	Alzheimer's disease: EIF2AK3
hsa04370__36	0.16295291479054	UP	1.39535880137417	0.183456277346569	VEGF signaling pathway: NOS3
hsa05321__92	0.164132650145739	UP	1.39145611970079	0.184673802169967	Inflammatory bowel disease (IBD): IL17F
hsa03320__32	0.166511407174158	UP	1.38365075635404	0.187238141280816	PPAR signaling pathway: FABP3
hsa04668__111	0.16845155889996	UP	1.37734642442012	0.189297590232377	TNF signaling pathway: BAG4
hsa04310__57	0.168544368525156	DOWN	-1.37704621813755	0.189297590232377	Wnt signaling pathway: SIAH1
hsa04064__94	0.172193947006978	DOWN	-1.36533817311741	0.193281019370437	NF-kappa B signaling pathway: BCL2L1*
hsa04390__78	0.174278596547032	DOWN	-1.35873363490093	0.195504168902611	Hippo signaling pathway: SOX2
hsa04151__4	0.174945830763647	UP	1.35663219092295	0.196135570408647	PI3K-Akt signaling pathway: RPS6
hsa05161__214	0.176574191439349	UP	1.3515286841193	0.197843116108847	Hepatitis B: CDKN1B
hsa04742__8	0.179086380780326	UP	1.34372332077255	0.200538325081188	Taste transduction: PLCB2
hsa05221__5	0.180059727776937	DOWN	-1.34072125794687	0.20150817658896	Acute myeloid leukemia: SPI1
hsa05169__83	0.184587534938063	UP	1.32691176894876	0.206452367945608	Epstein-Barr virus infection: GSK3B
hsa05160__8	0.187585516534683	UP	1.31790558047173	0.20968065768511	Hepatitis C: NFKB1
hsa04621__43	0.191332339378458	UP	1.30679794801673	0.213741656178433	NOD-like receptor signaling pathway: MAPK1
hsa05164__47	0.1957555980207	UP	1.29388907786633	0.21855304140279	Influenza A: CIITA
hsa04064__115	0.202052182911333	UP	1.27587670091227	0.225448961811399	NF-kappa B signaling pathway: XIAP
hsa05014__2	0.206762625576305	UP	1.2626676244793	0.230567936770254	Amyotrophic lateral sclerosis (ALS): SLC1A2
hsa04360__19	0.210347413800433	DOWN	-1.25276081715457	0.23442632890333	Axon guidance: CDC42
hsa05200__213	0.215196795300104	UP	1.23955174072159	0.239688665304621	Pathways in cancer: CSF2RA
hsa04066__37	0.220691466725966	UP	1.22484163287578	0.245663072261902	HIF-1 signaling pathway: PDHA1
hsa05164__19	0.222734971157518	UP	1.21943791978956	0.247791006989329	Influenza A: NFKB1
hsa04917__46	0.224104810330414	UP	1.21583544439875	0.24916741929636	Prolactin signaling pathway: GCK
hsa04810__31	0.229993803216488	DOWN	-1.2005249239878	0.255563782521455	Regulation of actin cytoskeleton: MSN
hsa04024__44 67	0.230460296473805	UP	1.19932409885753	0.255930790233026	cAMP signaling pathway: CREB3 CREBBP
hsa04014__43	0.234216467443511	UP	1.18971749781537	0.259948459732048	Ras signaling pathway: ELK1
hsa04360__101 103	0.238613364672612	UP	1.17860986536037	0.264672085135678	Axon guidance: DPYSL2 DPYSL5
hsa04650__119	0.240292151457954	DOWN	-1.17440697740442	0.266376963179643	Natural killer cell mediated cytotoxicity: KLRC4-KLRK1
hsa04064__131	0.253772482862213	UP	1.14138428632199	0.281154773171049	NF-kappa B signaling pathway: CCL4L1
hsa04024__123	0.254397491166841	UP	1.13988325490915	0.281681134886561	cAMP signaling pathway: PAK1
hsa04919__89	0.265444300497586	UP	1.11376530832577	0.293739599902806	Thyroid hormone signaling pathway: CASP9
hsa04360__122	0.268678890103055	UP	1.10626015126158	0.29714398734764	Axon guidance: CFL1**
hsa05321__19	0.273252623479163	UP	1.09575293137171	0.302024517363145	Inflammatory bowel disease (IBD): TNF
hsa04350__27	0.28202153737734	UP	1.07593931672225	0.311533491318061	TGF-beta signaling pathway: ACVR2A*
hsa05205__352	0.284986411331068	UP	1.06933477850577	0.314623658572901	Proteoglycans in cancer: ITGA5*
hsa05162__101	0.291116543202382	UP	1.05582549579022	0.321202574678377	Measles: CDKN1B
hsa04071__89	0.292078021569809	DOWN	-1.05372405181225	0.322074297259197	Sphingolipid signaling pathway: C00533
hsa05132__48	0.29469849234389	UP	1.04802013244347	0.324773294495113	Salmonella infection: KLC3
hsa05215__9	0.299426969086519	UP	1.03781311883617	0.32979089971487	Prostate cancer: CDKN1B
hsa04390__75	0.30054686734281	DOWN	-1.03541146857563	0.330830441556614	Hippo signaling pathway: NKD1
hsa05200__49	0.300967547921189	DOWN	-1.03451084972793	0.331099544814938	Pathways in cancer: CASP9
hsa04115__9	0.301669553505208	DOWN	-1.03300981831509	0.331638099603281	p53 signaling pathway: RPRM
hsa04015__11	0.301810085322837	DOWN	-1.03270961203252	0.331638099603281	Rap1 signaling pathway: RAC1
hsa04933__29	0.319427942480847	UP	0.995784239276706	0.350791995278499	AGE-RAGE signaling pathway in diabetic complications: ICAM1
hsa04071__48	0.324561686940228	UP	0.98527701938684	0.35622161785087	Sphingolipid signaling pathway: SMPD1
hsa04910__32	0.331988374470047	DOWN	-0.97026670525846	0.364160044150157	Insulin signaling pathway: EIF4E
hsa04010__65	0.337554226544222	UP	0.959159072803459	0.370049236684127	MAPK signaling pathway: ELK4
hsa05134__72	0.342874082452402	DOWN	-0.948651852913594	0.375662041357472	Legionellosis: IL12A
hsa05016__22 9	0.349173676219835	UP	0.936343395328322	0.382287570234458	Huntington's disease: DLG4 HTT
hsa05205__34	0.34932823740956	DOWN	-0.936043189045755	0.382287570234458	Proteoglycans in cancer: SLC9A1
hsa05215__35	0.354609147980855	UP	0.925836175438457	0.387840855096639	Prostate cancer: CASP9
hsa04066__49	0.360097744693706	DOWN	-0.915328955548591	0.393614695915924	HIF-1 signaling pathway: EPO
hsa04742__23 45	0.361833551830081	UP	0.912026686440347	0.395282118539955	Taste transduction: PKD1L3 PKD2L1
hsa04660__44	0.362941108060502	UP	0.909925242462374	0.396261674634331	T cell receptor signaling pathway: PAK4
hsa05212__12	0.378667067532843	DOWN	-0.88050502677075	0.413191300751574	Pancreatic cancer: CASP9
hsa04024__60	0.379643316844218	DOWN	-0.878703789075344	0.414016130209104	cAMP signaling pathway: PDE3A
hsa04064__51	0.381600453102825	DOWN	-0.875101313684533	0.415845930723482	NF-kappa B signaling pathway: TNFAIP3
hsa05142__84	0.381763826768497	UP	0.874801107401966	0.415845930723482	Chagas disease (American trypanosomiasis): NFKB1*
hsa05014__51	0.382417749476322	UP	0.873600282271695	0.416316889493632	Amyotrophic lateral sclerosis (ALS): DERL1
hsa05216__14	0.386849673089676	UP	0.86549471264237	0.420897820344818	Thyroid cancer: MAPK1*
hsa05162__62	0.388333916530415	DOWN	-0.862792856099262	0.422268188171672	Measles: IL12A
hsa04530__11 33	0.391976642010457	DOWN	-0.856188317882775	0.425982712745892	Tight junction: TJP1 CGN
hsa04971__52 53	0.402016192398695	DOWN	-0.838175940928719	0.436640708391415	Gastric acid secretion: EZR ACTB
hsa05142__29	0.408283423938345	DOWN	-0.827068308473718	0.443191538752253	Chagas disease (American trypanosomiasis): NOS2
hsa05200__80	0.412722035686375	DOWN	-0.819262945126961	0.447750984442666	Pathways in cancer: TP53
hsa04931__40	0.419779192749114	DOWN	-0.80695448754169	0.455144318047078	Insulin resistance: PRKCZ
hsa05211__41	0.422552331270215	UP	0.802151187020608	0.45788686877551	Renal cell carcinoma: PDGFB*
hsa04612__17 28	0.428830991947093	UP	0.791343760848175	0.464422728454517	Antigen processing and presentation: CD4 HLA-DMA
hsa04919__25	0.43076023865324	UP	0.788041491739931	0.466243368910966	Thyroid hormone signaling pathway: MTOR
hsa05133__94	0.43392802555553	DOWN	-0.782637778653715	0.469401704098354	Pertussis: IL12A
hsa04662__36	0.435516954810944	DOWN	-0.779935922110606	0.470849458049347	B cell receptor signaling pathway: CD79A
hsa05150__35	0.439059795309255	UP	0.773931796459254	0.47440675985399	Staphylococcus aureus infection: FCAR
hsa05166__83	0.440481700676049	UP	0.771530146198714	0.475669606649595	HTLV-I infection: NFKB2
hsa05216__12	0.442804869970595	DOWN	-0.764625401699659	0.477903705154938	Thyroid cancer: CDH1
hsa04950__30	0.443154680127468	UP	0.7670270519602	0.478006684247711	Maturity onset diabetes of the young: PAX6*
hsa04110__46	0.445299722312744	UP	0.763424576569389	0.480044852682528	Cell cycle: RB1
hsa04020__18	0.454300780253489	UP	0.748414262441009	0.488906738886773	Calcium signaling pathway: C00002
hsa04020__17	0.454300780253489	UP	0.748414262441009	0.488906738886773	Calcium signaling pathway: C00004
hsa04020__15	0.454300780253489	UP	0.748414262441009	0.488906738886773	Calcium signaling pathway: C13051
hsa05145__8	0.45683940799279	DOWN	-0.744211374485063	0.4913573254828	Toxoplasmosis: NFKB1
hsa05205__220	0.461027167066647	UP	0.737306629986008	0.495577830044754	Proteoglycans in cancer: FAS
hsa04115__27	0.462671677471512	UP	0.7346047734429	0.496973599012115	p53 signaling pathway: THBS1
hsa05220__6	0.462854602592443	UP	0.734304567160332	0.496973599012115	Chronic myeloid leukemia: TP53
hsa05168__138	0.464686070184246	UP	0.731302504334656	0.498655126142889	Herpes simplex infection: CHUK
hsa04740__39	0.485659435844057	DOWN	-0.697379194404518	0.520864200885265	Olfactory transduction: PRKG1*
hsa04360__20	0.489046997217007	DOWN	-0.691975481318302	0.524198121945668	Axon guidance: ROCK1
hsa04933__62	0.498713816002133	DOWN	-0.676664960907354	0.534254994451544	AGE-RAGE signaling pathway in diabetic complications: AGER**
hsa04064__4	0.501003034142738	DOWN	-0.673062485516543	0.536401539119205	NF-kappa B signaling pathway: BIRC2
hsa04621__6	0.501767342357361	DOWN	-0.671861660386273	0.536608330272898	NOD-like receptor signaling pathway: NFKB1
hsa05168__9	0.501767342357361	DOWN	-0.671861660386273	0.536608330272898	Herpes simplex infection: NFKB1
hsa04623__25	0.502149727782199	DOWN	-0.671261247821138	0.536711796645479	Cytosolic DNA-sensing pathway: NFKB1*
hsa05205__188	0.502532267317824	DOWN	-0.670660835256003	0.536815310000109	Proteoglycans in cancer: TNF
hsa04014__33	0.506174064622964	UP	0.664956915887218	0.540398333765084	Ras signaling pathway: BCL2L1
hsa04620__40	0.507903959716379	DOWN	-0.66225505934411	0.541937274450355	Toll-like receptor signaling pathway: CCL5
hsa04750__7	0.513112144107031	DOWN	-0.654149489714785	0.546873351546859	Inflammatory mediator regulation of TRP channels: TRPV1
hsa04750__58	0.513112144107031	DOWN	-0.654149489714785	0.546873351546859	Inflammatory mediator regulation of TRP channels: TRPV1**
hsa04976__36	0.514079582282928	DOWN	-0.652648458301947	0.547593840765092	Bile secretion: SLC10A1
hsa05205__142	0.517182203454303	DOWN	-0.647845157780865	0.550376531794405	Proteoglycans in cancer: CTNNB1
hsa04973__36	0.517376429227156	DOWN	-0.647544951498298	0.550376531794405	Carbohydrate digestion and absorption: SLC2A2
hsa04611__25	0.517570692751844	UP	0.64724474521573	0.550376531794405	Platelet activation: ORAI1
hsa04071__66	0.518542576296448	UP	0.645743713802892	0.551098133971168	Sphingolipid signaling pathway: C01245
hsa04064__132	0.532247293797159	DOWN	-0.624729274023161	0.56534350765679	NF-kappa B signaling pathway: VCAM1
hsa05164__65 66	0.535603048170807	DOWN	-0.619625767219512	0.568586512719178	Influenza A: DNAJC3 HSPA1A
hsa04611__34	0.540557270899215	DOWN	-0.612120610155322	0.573521802382623	Platelet activation: C02198*
hsa04917__48	0.542545355339642	UP	0.609118547329646	0.575306276909248	Prolactin signaling pathway: CCND2
hsa05200__217	0.553544540826406	UP	0.592607201788428	0.586638574288109	Pathways in cancer: E2F1*
hsa04742__27	0.558176374585873	UP	0.585702457289374	0.591213871390562	Taste transduction: CALHM1
hsa04620__46	0.568717289850032	UP	0.570091730595859	0.602039316973639	Toll-like receptor signaling pathway: TNF
hsa04961__26	0.573000999531384	UP	0.563787398661939	0.606232476418621	Endocrine and other factor-regulated calcium reabsorption: TRPV5*
hsa04530__14 20 43	0.574023182289874	DOWN	-0.562286367249102	0.606846957512372	Tight junction: CTNNA1 ACTB ACTN4
hsa04024__3	0.574227722435869	UP	0.561986160966534	0.606846957512372	cAMP signaling pathway: RYR2
hsa04014__76	0.589458574060584	UP	0.539770896056532	0.622592839044316	Ras signaling pathway: RALBP1*
hsa04151__96	0.592776065975225	DOWN	-0.534967595535451	0.625612778981847	PI3K-Akt signaling pathway: BCL2
hsa05161__130	0.592983693116908	UP	0.534667389252883	0.625612778981847	Hepatitis B: FASLG*
hsa04115__36	0.59464590863376	UP	0.532265738992342	0.627014400854565	p53 signaling pathway: EI24
hsa04115__3	0.600271538510012	UP	0.524160169363017	0.632591262400624	p53 signaling pathway: GADD45G
hsa04261__14 16	0.606550310274623	DOWN	-0.515153980885989	0.638849794285884	Adrenergic signaling in cardiomyocytes: TNNI3 TPM1
hsa04150__33	0.609490416022112	UP	0.510951092930043	0.641586830087142	mTOR signaling pathway: RPS6
hsa04742__54	0.616445522614704	DOWN	-0.501044285605313	0.648181945715181	Taste transduction: P2RX2*
hsa04742__40	0.616445522614704	DOWN	-0.501044285605313	0.648181945715181	Taste transduction: P2RX2
hsa04540__18 19	0.625135019328575	DOWN	-0.488735828020041	0.656951175234	Gap junction: GJA1 GJA1***
hsa04310__32	0.649568148026033	DOWN	-0.454512311807336	0.682246254969768	Wnt signaling pathway: PPARD
hsa04062__53	0.651513684849556	DOWN	-0.451810455264227	0.683907382029227	Chemokine signaling pathway: NFKB1
hsa04010__64	0.652379131102277	UP	0.450609630133957	0.684433493769502	MAPK signaling pathway: DDIT3
hsa04660__56	0.65497827547359	DOWN	-0.447007154743146	0.686776885945801	T cell receptor signaling pathway: CD3E
hsa04750__39	0.65736450369542	DOWN	-0.443704885634902	0.688894535662964	Inflammatory mediator regulation of TRP channels: C01245*
hsa04014__45	0.662365167996148	UP	0.436800141135848	0.693748133034984	Ras signaling pathway: RAB5A
hsa05200__215	0.675480961306115	UP	0.418787764181792	0.707091212420162	Pathways in cancer: CSF1R
hsa03320__29	0.68207630617474	DOWN	-0.409781575704764	0.713597649945621	PPAR signaling pathway: OLR1
hsa04919__42	0.687812005636454	DOWN	-0.401976212358007	0.719028894776615	Thyroid hormone signaling pathway: SLC2A1
hsa04210__69	0.688032971159316	DOWN	-0.401676006075439	0.719028894776615	Apoptosis: PTPN13
hsa04024__115	0.69112927774471	UP	0.397473118119493	0.721863208939583	cAMP signaling pathway: F2R
hsa05132__54	0.701116509309549	UP	0.383963835403951	0.731887733884801	Salmonella infection: IL1B
hsa04064__97	0.708696934593215	DOWN	-0.373756821796653	0.739212708197625	NF-kappa B signaling pathway: PLCG2
hsa04014__100	0.708920330054348	UP	0.373456615514086	0.739212708197625	Ras signaling pathway: REL
hsa04151__63	0.710708393622328	UP	0.371054965253545	0.740666151756159	PI3K-Akt signaling pathway: CASP9
hsa04350__44 45	0.712945712879411	UP	0.368052902427869	0.742585917128832	TGF-beta signaling pathway: TGFBR2 TGFBR1
hsa05200__52	0.719447857558291	DOWN	-0.359346920233409	0.748943226787827	Pathways in cancer: CDKN1B
hsa04064__116	0.721694720158595	UP	0.356344857407733	0.750502927675634	NF-kappa B signaling pathway: GADD45B
hsa04742__37	0.721919439861662	DOWN	-0.356044651125165	0.750502927675634	Taste transduction: P2RY4
hsa05152__9	0.722144381712371	UP	0.355744444842598	0.750502927675634	Tuberculosis: TCIRG1
hsa04915__30	0.724619232716105	DOWN	-0.352442175734354	0.752061047436068	Estrogen signaling pathway: CREB3*
hsa05200__173	0.724844362377179	DOWN	-0.352141969451786	0.752061047436068	Pathways in cancer: CCNA1
hsa05221__16	0.724844362377179	DOWN	-0.352141969451786	0.752061047436068	Acute myeloid leukemia: CCNA1
hsa05152__24 25	0.728449656723143	DOWN	-0.347338668930705	0.755384605398889	Tuberculosis: ITGB2 ITGAM
hsa04014__68	0.733868867079233	UP	0.340133718149083	0.760584446355146	Ras signaling pathway: RALGDS*
hsa04920__5	0.73658347010096	UP	0.336531242758272	0.762977034354853	Adipocytokine signaling pathway: NFKBIA
hsa04064__50	0.743157288755752	DOWN	-0.327825260563811	0.76936228406174	NF-kappa B signaling pathway: NFKBIA*
hsa04151__33	0.753167074184609	UP	0.314616184130837	0.779102540892615	PI3K-Akt signaling pathway: TP53
hsa04115__1	0.753395059500735	DOWN	-0.31431597784827	0.779102540892615	p53 signaling pathway: SIAH1
hsa03320__61	0.755219714593768	UP	0.311914327587729	0.780559870033933	PPAR signaling pathway: APOA1
hsa04310__33	0.758873115420176	DOWN	-0.307111027066648	0.783904664032167	Wnt signaling pathway: CCND1
hsa04916__4	0.769635869105254	UP	0.293001331785971	0.794585603323501	Melanogenesis: TYR
hsa04750__53	0.772391025811147	UP	0.28939885639516	0.796992167764495	Inflammatory mediator regulation of TRP channels: TRPM8
hsa05134__69	0.775149054915225	DOWN	-0.285796381004348	0.799399052791277	Legionellosis: IL1B*
hsa05220__25	0.784824301883289	UP	0.27318771713651	0.808933002325124	Chronic myeloid leukemia: BCL2L1*
hsa05200__48	0.79476446653917	DOWN	-0.260278846986103	0.818729403852577	Pathways in cancer: MTOR
hsa04360__96	0.805667486970992	UP	0.246169151705426	0.829506415352599	Axon guidance: GSK3B
hsa04917__33	0.806364733290816	UP	0.245268532857723	0.829769624235182	Prolactin signaling pathway: CSN2
hsa04666__51	0.809155252648971	DOWN	-0.241666057466912	0.8321853966762	Fc gamma R-mediated phagocytosis: NCF1
hsa04650__39	0.810318687887238	UP	0.240165026054074	0.832926047341423	Natural killer cell mediated cytotoxicity: FAS
hsa05162__78	0.811482542351681	UP	0.238663994641236	0.833666318796506	Measles: FAS
hsa04961__13	0.820341274043293	DOWN	-0.227256155903668	0.842306696135163	Endocrine and other factor-regulated calcium reabsorption: ATP2B1
hsa05133__46	0.821742144929246	UP	0.225454918208262	0.843284265604617	Pertussis: CFL1
hsa05162__20	0.836015925227405	DOWN	-0.207142334971639	0.857463932042737	Measles: NFKB1
hsa05145__10	0.847286084279745	DOWN	-0.192732433408395	0.868549128402422	Toxoplasmosis: MAPK8
hsa04722__34	0.86897282745903	UP	0.165113455412176	0.890294407194939	Neurotrophin signaling pathway: GSK3B
hsa04933__78	0.881512270286263	DOWN	-0.149202522436094	0.902649349246805	AGE-RAGE signaling pathway in diabetic complications: TGFB1
hsa04064__128	0.883407678961328	UP	0.146800872175553	0.904097510222405	NF-kappa B signaling pathway: IL1B*
hsa04670__86	0.887200488443824	UP	0.141997571654471	0.907484876312436	Leukocyte transendothelial migration: ACTB
hsa04910__20	0.889809550060632	UP	0.138695302546228	0.90965840291835	Insulin signaling pathway: PKLR
hsa05321__75	0.899069288261279	UP	0.126987257526092	0.918624900839012	Inflammatory bowel disease (IBD): IL10
hsa05200__195	0.911912917015828	UP	0.110776118267442	0.931241506017794	Pathways in cancer: BIRC8
hsa04350__32	0.926210508623416	UP	0.0927637413133862	0.945328378980662	TGF-beta signaling pathway: RPS6KB1
hsa05231__17	0.927164581041949	UP	0.0915629161831158	0.945788408131282	Choline metabolism in cancer: SLC44A3
hsa04380__51	0.929788816128332	UP	0.0882606470748723	0.947950724636536	Osteoclast differentiation: FOS*
hsa05152__112	0.930504650339177	UP	0.0873600282271695	0.948166072661233	Tuberculosis: IFNGR1
hsa05169__117	0.931459183316546	UP	0.0861592030968992	0.948624284797719	Epstein-Barr virus infection: CDKN1A
hsa04010__107	0.93336854367791	DOWN	-0.0837575528363584	0.95005389684225	MAPK signaling pathway: MAP3K2
hsa05162__58	0.935039548900365	UP	0.0816561088583853	0.951210228821237	Measles: STAT3
hsa05321__74	0.935517031858247	UP	0.0810556962932501	0.951210228821237	Inflammatory bowel disease (IBD): IL5
hsa05010__51	0.943159797369667	DOWN	-0.0714490952510871	0.958462552329694	Alzheimer's disease: ATF6
hsa05205__113	0.952481428732211	UP	0.059741050230951	0.967412218696121	Proteoglycans in cancer: TP53
hsa05161__227	0.954633544722322	UP	0.0570391936878427	0.969074246641407	Hepatitis B: MYD88*
hsa04380__48	0.959895633651091	DOWN	-0.0504346554713556	0.973889792457019	Osteoclast differentiation: NFATC1
hsa04520__7 68	0.963245160191546	UP	0.0462317675154093	0.976760742579555	Adherens junction: CDH1 CTNNB1
hsa04750__62	0.964441570401631	DOWN	-0.0447307361025713	0.977161919960164	Inflammatory mediator regulation of TRP channels: TRPM8*
hsa05134__9	0.964680873616872	UP	0.0444305298200037	0.977161919960164	Legionellosis: CASP7
hsa05231__38	0.966595335517015	UP	0.042028879559463	0.978573618230858	Choline metabolism in cancer: RPS6KB1
hsa04270__46	0.981198638590769	DOWN	-0.0237162963228398	0.992822962795937	Vascular smooth muscle contraction: ITPR1*
hsa04919__84	0.995568718558939	UP	0.00570391936878427	1	Thyroid hormone signaling pathway: TP53*
hsa04152__33	1	0	0	1	AMPK signaling pathway: CPT1C
hsa04152__41	1	0	0	1	AMPK signaling pathway: FBP1
hsa04211__2	1	0	0	1	Longevity regulating pathway - mammal: RPS6KB1
hsa04911__41	1	0	0	1	Insulin secretion: ABCC8
hsa04911__35	1	0	0	1	Insulin secretion: TRPM4
hsa04922__67	1	0	0	1	Glucagon signaling pathway: FBP1
hsa04922__60	1	0	0	1	Glucagon signaling pathway: CPT1C*
hsa04924__34	1	0	0	1	Renin secretion: REN
hsa04924__47	1	0	0	1	Renin secretion: KCNMA1
hsa04931__151	1	0	0	1	Insulin resistance: CPT1A
hsa04931__29	1	0	0	1	Insulin resistance: CPT1B
hsa04960__15	1	0	0	1	Aldosterone-regulated sodium reabsorption: C00762
hsa05030__13	1	0	0	1	Cocaine addiction: SLC6A3
hsa05031__15	1	0	0	1	Amphetamine addiction: MAOA
hsa05031__77	1	0	0	1	Amphetamine addiction: MAOA*
hsa05034__7	1	0	0	1	Alcoholism: GRIN3A
hsa05034__75	1	0	0	1	Alcoholism: SLC29A1
hsa05140__37	1	0	0	1	Leishmaniasis: ELK1
hsa05140__55	1	0	0	1	Leishmaniasis: JUN
hsa05140__41 57	1	0	0	1	Leishmaniasis: NOS2 CYBA
hsa05211__12	1	0	0	1	Renal cell carcinoma: EGLN2